Incidental Mutation 'R7427:Ttn'
ID 576148
Institutional Source Beutler Lab
Gene Symbol Ttn
Ensembl Gene ENSMUSG00000051747
Gene Name titin
Synonyms 1100001C23Rik, L56, mdm, shru, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, connectin
MMRRC Submission
Accession Numbers

NCBI RefSeq: NM_011652.3, NM_028004.2; MGI: 98864
Essential gene? Essential (E-score: 1.000) question?
Stock # R7427 (G1)
Quality Score 225.009
Status Validated
Chromosome 2
Chromosomal Location 76703980-76982547 bp(-) (GRCm38)
Type of Mutation missense
DNA Base Change (assembly) T to G at 76720354 bp (GRCm38)
Zygosity Heterozygous
Amino Acid Change Aspartic acid to Alanine at position 31528 (D31528A)
Ref Sequence ENSEMBL: ENSMUSP00000097561 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000011934] [ENSMUST00000099981] [ENSMUST00000111846] [ENSMUST00000111882]
AlphaFold no structure available at present
Predicted Effect probably damaging
Transcript: ENSMUST00000011934
AA Change: D23201A

PolyPhen 2 Score 0.987 (Sensitivity: 0.73; Specificity: 0.96)
SMART Domains Protein: ENSMUSP00000011934
Gene: ENSMUSG00000051747
AA Change: D23201A

DomainStartEndE-ValueType
IGc2 18 87 3.97e-7 SMART
IG 110 194 4.03e-8 SMART
low complexity region 251 270 N/A INTRINSIC
low complexity region 388 407 N/A INTRINSIC
Pfam:Titin_Z 412 454 4.1e-15 PFAM
Pfam:Titin_Z 463 504 2e-14 PFAM
Pfam:Titin_Z 509 548 7.5e-14 PFAM
Pfam:Titin_Z 553 594 2.3e-13 PFAM
Pfam:Titin_Z 599 640 4.1e-10 PFAM
Pfam:Titin_Z 644 686 7.3e-8 PFAM
low complexity region 885 901 N/A INTRINSIC
IGc2 912 979 7.57e-13 SMART
IGc2 1050 1119 9.12e-7 SMART
low complexity region 1169 1177 N/A INTRINSIC
low complexity region 1223 1233 N/A INTRINSIC
IGc2 1259 1327 6.55e-8 SMART
low complexity region 1355 1374 N/A INTRINSIC
IG 1423 1508 8.72e-4 SMART
IG 1522 1610 1.63e-3 SMART
low complexity region 1657 1668 N/A INTRINSIC
IG_like 1669 1755 7.06e0 SMART
IG 1807 1890 7.94e-7 SMART
low complexity region 1988 1999 N/A INTRINSIC
low complexity region 2002 2016 N/A INTRINSIC
IG 2044 2129 6.51e-3 SMART
IG 2140 2223 1.81e-1 SMART
IG 2233 2312 1.34e-4 SMART
IG 2322 2403 2.94e0 SMART
IG 2411 2491 8.99e-6 SMART
IG 2499 2578 1.97e0 SMART
IG 2586 2665 2.18e-4 SMART
IG 2673 2753 5e0 SMART
IG 2761 2840 2.41e-6 SMART
IG 2848 2927 3.3e-4 SMART
IG 2935 3014 6.35e-6 SMART
IG 3024 3103 1.17e-4 SMART
IG 3113 3194 6.97e-3 SMART
IGc2 3211 3278 8.26e-5 SMART
low complexity region 3287 3296 N/A INTRINSIC
IG 3311 3394 1.66e-9 SMART
IG 3469 3553 1.54e-4 SMART
IGc2 3591 3659 8.13e-4 SMART
low complexity region 3876 3887 N/A INTRINSIC
low complexity region 3950 3963 N/A INTRINSIC
low complexity region 4016 4030 N/A INTRINSIC
low complexity region 4148 4160 N/A INTRINSIC
IGc2 4217 4282 1.68e-5 SMART
IGc2 4310 4377 6.02e-7 SMART
low complexity region 4398 4414 N/A INTRINSIC
low complexity region 4419 4461 N/A INTRINSIC
low complexity region 4474 4491 N/A INTRINSIC
low complexity region 4497 4516 N/A INTRINSIC
low complexity region 4518 4532 N/A INTRINSIC
IGc2 4593 4659 3.85e-5 SMART
IG 4681 4763 4.49e-6 SMART
IG 4774 4862 1.1e0 SMART
IG_like 4865 4944 9.78e1 SMART
IG 4954 5032 5.45e-5 SMART
IG 5042 5121 3.08e-4 SMART
IG 5131 5209 1.93e-5 SMART
IG 5219 5298 1.81e-1 SMART
IG 5308 5394 9.49e-5 SMART
IG 5397 5476 2.94e-1 SMART
IG 5486 5574 4.29e-3 SMART
IG_like 5575 5654 7.3e1 SMART
IG 5664 5743 1.85e-7 SMART
IG 5753 5832 5.62e-7 SMART
IG 5842 5921 2.1e-6 SMART
IGc2 5937 6003 1.03e-5 SMART
IG 6020 6099 6.02e-7 SMART
IG 6108 6192 1e-3 SMART
IG 6202 6281 7.36e-2 SMART
IG 6291 6370 1.25e-4 SMART
IG 6380 6459 2.08e-1 SMART
IG 6468 6549 1.56e-5 SMART
FN3 6552 6635 1.85e-14 SMART
FN3 6653 6736 1.75e-15 SMART
FN3 6754 6837 4.44e-17 SMART
IG_like 6869 6936 1.79e0 SMART
FN3 6950 7032 7.73e-17 SMART
FN3 7050 7132 1.22e-14 SMART
IG 7159 7243 2.92e-5 SMART
FN3 7246 7328 4.08e-16 SMART
FN3 7345 7428 3.05e-15 SMART
FN3 7446 7528 1.09e-16 SMART
FN3 7546 7628 2.34e-16 SMART
FN3 7646 7729 3.7e-14 SMART
FN3 7747 7831 2.21e-12 SMART
IG 7855 7939 8.26e-5 SMART
FN3 7942 8024 1.15e-15 SMART
FN3 8042 8125 3.37e-17 SMART
IG 8148 8261 3.74e-3 SMART
FN3 8264 8348 7.62e-16 SMART
FN3 8365 8447 8.75e-16 SMART
FN3 8464 8547 1.95e-13 SMART
IG 8573 8656 3.79e-4 SMART
FN3 8659 8740 6.59e-11 SMART
FN3 8757 8840 3.7e-14 SMART
IGc2 8873 8946 2.21e-5 SMART
FN3 8960 9044 6.73e-17 SMART
FN3 9061 9149 4.95e-15 SMART
FN3 9167 9252 7.11e-16 SMART
IG 9279 9371 1.81e-1 SMART
FN3 9374 9456 3.81e-16 SMART
FN3 9474 9562 3.93e-18 SMART
IG 9585 9676 3.65e-6 SMART
FN3 9679 9762 2.19e-16 SMART
FN3 9779 9866 4.21e-18 SMART
FN3 9880 9966 5.95e-18 SMART
IG 9993 10075 5.28e-3 SMART
FN3 10078 10161 1.51e-10 SMART
FN3 10179 10262 2.34e-16 SMART
IG 10287 10371 2.5e-4 SMART
FN3 10374 10457 1.82e-13 SMART
FN3 10474 10557 6.73e-17 SMART
FN3 10575 10660 8.42e-18 SMART
IG 10687 10769 9.12e-7 SMART
FN3 10772 10854 1.14e-14 SMART
FN3 10872 10953 1.14e-14 SMART
IG 10979 11063 7.3e-6 SMART
FN3 11066 11149 2.19e-16 SMART
FN3 11166 11248 4.38e-16 SMART
FN3 11266 11350 4.88e-14 SMART
IGc2 11383 11450 1.44e-4 SMART
FN3 11464 11545 1.58e-13 SMART
FN3 11563 11646 6.05e-10 SMART
IG 11670 11756 9.12e-7 SMART
FN3 11759 11841 4.76e-17 SMART
FN3 11858 11941 1.14e-14 SMART
FN3 11959 12048 1.66e-16 SMART
IG 12075 12158 9.34e-4 SMART
FN3 12161 12243 6.14e-20 SMART
FN3 12261 12344 4.83e-18 SMART
IG 12367 12451 6.02e-7 SMART
FN3 12454 12537 2.44e-14 SMART
FN3 12554 12637 2.03e-11 SMART
FN3 12652 12737 7.06e-11 SMART
IG 12764 12848 2.44e-7 SMART
FN3 12851 12933 1.38e-13 SMART
FN3 12950 13033 4.69e-16 SMART
FN3 13051 13135 1.93e-17 SMART
IG 13162 13246 3.02e0 SMART
FN3 13249 13331 1.39e-18 SMART
FN3 13346 13426 5.69e-15 SMART
IG 13451 13535 7.08e-4 SMART
FN3 13538 13621 1.22e-14 SMART
FN3 13638 13721 3.5e-15 SMART
FN3 13736 13819 1.92e-12 SMART
IG 13847 13932 1.46e-5 SMART
FN3 13935 14017 1.2e-13 SMART
FN3 14034 14117 3.72e-19 SMART
FN3 14135 14219 1.38e-13 SMART
IG 14245 14327 8.59e-3 SMART
FN3 14330 14412 1.37e-17 SMART
FN3 14427 14508 7.5e-15 SMART
IG 14534 14618 1.81e-1 SMART
FN3 14621 14704 2.15e-15 SMART
FN3 14721 14804 5.31e-15 SMART
FN3 14819 14902 6.95e-10 SMART
IG 14930 15014 7.25e-1 SMART
FN3 15017 15100 8.75e-16 SMART
FN3 15117 15200 5.86e-17 SMART
FN3 15218 15302 4.31e-15 SMART
IG 15329 15411 4.78e-1 SMART
IG_like 15345 15400 1.79e0 SMART
FN3 15414 15496 1.02e-16 SMART
FN3 15511 15592 3.14e-17 SMART
IGc2 15622 15689 4.43e-5 SMART
FN3 15703 15786 3.22e-14 SMART
FN3 15803 15886 1.12e-13 SMART
FN3 15901 15984 1.58e-13 SMART
IG 16012 16096 6.97e-3 SMART
FN3 16099 16182 5.23e-14 SMART
FN3 16199 16282 3.05e-15 SMART
FN3 16300 16384 1.98e-14 SMART
IG 16411 16493 2.5e-4 SMART
FN3 16496 16578 2.69e-16 SMART
FN3 16593 16674 5.86e-17 SMART
IGc2 16704 16771 1.09e-4 SMART
FN3 16785 16868 2.07e-17 SMART
FN3 16885 16968 1.29e-13 SMART
FN3 16983 17066 2.33e-11 SMART
IG 17094 17178 8.72e-4 SMART
FN3 17181 17264 4.62e-15 SMART
FN3 17281 17364 1.47e-17 SMART
FN3 17382 17466 2.61e-14 SMART
IG 17493 17575 3.23e-7 SMART
FN3 17578 17660 1.22e-14 SMART
FN3 17675 17756 1.66e-16 SMART
IGc2 17786 17853 5.16e-6 SMART
FN3 17867 17950 1.88e-15 SMART
FN3 17967 18050 4.8e-13 SMART
FN3 18065 18149 6e-14 SMART
IG 18176 18261 2.08e0 SMART
FN3 18264 18347 2.04e-16 SMART
FN3 18364 18447 6.84e-18 SMART
FN3 18465 18549 1.9e-16 SMART
IG 18576 18658 2.3e-3 SMART
FN3 18661 18743 5.86e-17 SMART
FN3 18758 18839 1.17e-16 SMART
IG 18863 18947 2.08e-1 SMART
FN3 18950 19032 1.38e-13 SMART
FN3 19049 19132 3.64e-13 SMART
FN3 19147 19231 2.72e-12 SMART
IG 19258 19342 3.27e0 SMART
FN3 19345 19428 1.09e-11 SMART
FN3 19445 19528 6.53e-15 SMART
FN3 19546 19628 1.67e-12 SMART
IGc2 19661 19726 8.26e-5 SMART
FN3 19740 19822 2.8e-14 SMART
FN3 19837 19918 4.08e-16 SMART
IG 19945 20029 8.33e-1 SMART
FN3 20032 20115 1.42e-15 SMART
FN3 20132 20215 1.16e-11 SMART
FN3 20230 20313 4.31e-15 SMART
IG 20341 20425 4.16e-1 SMART
FN3 20428 20511 6.34e-13 SMART
FN3 20528 20611 4.24e-14 SMART
FN3 20629 20713 9.52e-17 SMART
IGc2 20746 20813 7.7e-5 SMART
FN3 20828 20910 9.99e-11 SMART
FN3 20925 21006 1.3e-9 SMART
IG 21032 21114 2.64e0 SMART
FN3 21119 21202 4.48e-13 SMART
FN3 21219 21302 1.72e-14 SMART
FN3 21317 21399 1.27e-12 SMART
IGc2 21433 21500 4.07e-4 SMART
FN3 21514 21597 2.46e-10 SMART
FN3 21614 21698 5.1e-17 SMART
FN3 21716 21799 2.93e-17 SMART
IG 21826 21908 2.03e-4 SMART
FN3 21911 21993 1.2e-13 SMART
FN3 22008 22089 2.48e-15 SMART
IG 22116 22200 2.18e-4 SMART
FN3 22203 22286 3.96e-14 SMART
FN3 22303 22386 9.75e-14 SMART
FN3 22401 22487 6.24e-12 SMART
IG 22516 22600 2.94e0 SMART
FN3 22603 22685 1.2e-13 SMART
FN3 22702 22786 1.07e-10 SMART
FN3 22804 22888 8.88e-17 SMART
IG 22915 22997 3.28e-8 SMART
FN3 23000 23082 5.07e-12 SMART
FN3 23097 23180 2.4e-13 SMART
IG 23207 23291 8.26e-5 SMART
FN3 23294 23377 1.44e-16 SMART
FN3 23394 23477 2.76e-13 SMART
FN3 23495 23578 6.63e-16 SMART
IG 23605 23685 5.66e-3 SMART
FN3 23690 23773 9.9e-15 SMART
FN3 23791 23875 9.16e-19 SMART
FN3 23893 23976 3.32e-16 SMART
IGc2 24007 24074 3.51e-8 SMART
IG 24097 24182 2.79e0 SMART
FN3 24185 24269 6.79e-13 SMART
FN3 24287 24370 3.7e-14 SMART
IG 24396 24482 1.85e-7 SMART
IG 24496 24581 1.55e0 SMART
FN3 24584 24665 1.33e-15 SMART
low complexity region 24687 24699 N/A INTRINSIC
S_TKc 24713 24967 9.98e-74 SMART
IG 25036 25121 7.36e-2 SMART
IG 25157 25244 1.78e-9 SMART
IG 25262 25347 1.11e-5 SMART
low complexity region 25533 25549 N/A INTRINSIC
low complexity region 25571 25583 N/A INTRINSIC
low complexity region 25585 25603 N/A INTRINSIC
low complexity region 25688 25698 N/A INTRINSIC
low complexity region 25704 25715 N/A INTRINSIC
low complexity region 25716 25738 N/A INTRINSIC
low complexity region 25767 25799 N/A INTRINSIC
IG 25842 25926 4.6e-3 SMART
IGc2 26035 26102 2.42e-11 SMART
IG 26183 26281 2.64e-3 SMART
IGc2 26326 26393 2.1e-6 SMART
IG 26507 26589 4.53e-2 SMART
IGc2 26608 26675 4.59e-12 SMART
low complexity region 26701 26720 N/A INTRINSIC
low complexity region 26724 26736 N/A INTRINSIC
low complexity region 26743 26771 N/A INTRINSIC
IG 26797 26884 8.51e-7 SMART
Predicted Effect probably damaging
Transcript: ENSMUST00000099981
AA Change: D31528A

PolyPhen 2 Score 0.987 (Sensitivity: 0.73; Specificity: 0.96)
SMART Domains Protein: ENSMUSP00000097561
Gene: ENSMUSG00000051747
AA Change: D31528A

DomainStartEndE-ValueType
IGc2 18 87 3.97e-7 SMART
IG 110 194 4.03e-8 SMART
low complexity region 251 270 N/A INTRINSIC
Pfam:Titin_Z 382 454 4.6e-13 PFAM
Pfam:Titin_Z 463 504 1.2e-10 PFAM
Pfam:Titin_Z 509 548 2e-11 PFAM
Pfam:Titin_Z 553 594 8.3e-8 PFAM
Pfam:Titin_Z 599 640 5.4e-12 PFAM
Pfam:Titin_Z 645 686 5.4e-10 PFAM
Pfam:Titin_Z 696 730 5.8e-9 PFAM
low complexity region 931 947 N/A INTRINSIC
IGc2 958 1025 7.57e-13 SMART
IGc2 1096 1165 9.12e-7 SMART
low complexity region 1215 1223 N/A INTRINSIC
low complexity region 1269 1279 N/A INTRINSIC
IGc2 1305 1373 6.55e-8 SMART
low complexity region 1401 1420 N/A INTRINSIC
IG 1469 1554 8.72e-4 SMART
IG 1568 1656 1.63e-3 SMART
low complexity region 1703 1714 N/A INTRINSIC
IG_like 1715 1801 7.06e0 SMART
IG 1853 1936 7.94e-7 SMART
low complexity region 2034 2045 N/A INTRINSIC
low complexity region 2048 2062 N/A INTRINSIC
IG 2090 2175 6.51e-3 SMART
IG 2186 2269 1.81e-1 SMART
IG 2279 2358 1.34e-4 SMART
IG 2368 2449 2.94e0 SMART
IG 2457 2537 8.99e-6 SMART
IG 2545 2624 1.97e0 SMART
IG 2632 2711 2.18e-4 SMART
IG 2719 2799 5e0 SMART
IG 2807 2886 2.41e-6 SMART
IG 2894 2973 3.3e-4 SMART
IG 2981 3060 6.35e-6 SMART
IG 3070 3149 1.17e-4 SMART
IG 3159 3240 6.97e-3 SMART
IGc2 3257 3324 8.26e-5 SMART
low complexity region 3333 3342 N/A INTRINSIC
IG 3357 3440 1.66e-9 SMART
IG 3515 3599 1.54e-4 SMART
IGc2 3637 3705 8.13e-4 SMART
low complexity region 3922 3933 N/A INTRINSIC
low complexity region 3996 4009 N/A INTRINSIC
low complexity region 4062 4076 N/A INTRINSIC
low complexity region 4194 4206 N/A INTRINSIC
IGc2 4263 4328 1.68e-5 SMART
IGc2 4356 4423 6.02e-7 SMART
IGc2 4451 4518 1.69e-10 SMART
IGc2 4544 4611 5.79e-9 SMART
IGc2 4638 4705 3.5e-17 SMART
IGc2 4731 4798 2.92e-5 SMART
IGc2 4824 4891 1.7e-6 SMART
IG 4911 4995 2.83e-3 SMART
IGc2 5013 5080 2.35e-9 SMART
IGc2 5106 5173 4.82e-6 SMART
IGc2 5200 5267 7.13e-9 SMART
IG 5287 5371 9.34e-4 SMART
IG 5380 5464 1.32e-3 SMART
IG 5473 5557 5.75e-4 SMART
IGc2 5575 5642 3.03e-12 SMART
IGc2 5668 5735 2.68e-4 SMART
IGc2 5762 5829 1.47e-10 SMART
IGc2 5855 5922 2.28e-7 SMART
IGc2 5948 6015 3.76e-8 SMART
IGc2 6041 6108 1.31e-7 SMART
IGc2 6137 6204 2.44e-7 SMART
IG 6224 6308 2.1e-6 SMART
IGc2 6324 6391 7.13e-9 SMART
IGc2 6417 6484 5.04e-9 SMART
IG 6504 6589 3.46e-7 SMART
IGc2 6604 6671 9.55e-10 SMART
IGc2 6700 6767 4.7e-9 SMART
IGc2 6793 6860 8.26e-5 SMART
IGc2 6886 6953 2.58e-6 SMART
IGc2 6979 7046 1.85e-16 SMART
IGc2 7075 7142 1.33e-8 SMART
IGc2 7171 7238 1.3e-11 SMART
IGc2 7265 7332 1.6e-11 SMART
IGc2 7358 7425 6.21e-9 SMART
IGc2 7451 7519 8.13e-4 SMART
IGc2 7545 7612 1.03e-5 SMART
IGc2 7641 7708 1.28e-10 SMART
IGc2 7734 7801 7.19e-5 SMART
IGc2 7827 7894 2.34e-4 SMART
IGc2 7920 7987 1.54e-13 SMART
IGc2 8016 8083 9.12e-7 SMART
IGc2 8112 8179 1.53e-8 SMART
IGc2 8206 8273 3.01e-7 SMART
IGc2 8299 8366 5.16e-6 SMART
IGc2 8392 8460 1.65e-4 SMART
IGc2 8486 8553 4.63e-8 SMART
IGc2 8582 8649 3.38e-10 SMART
IGc2 8675 8742 1.04e-10 SMART
IGc2 8768 8835 2.54e-5 SMART
IGc2 8861 8928 3.79e-13 SMART
IGc2 8957 9024 1.18e-9 SMART
IGc2 9053 9120 8e-12 SMART
IGc2 9150 9217 5.32e-8 SMART
IGc2 9246 9313 8.57e-12 SMART
low complexity region 9326 9337 N/A INTRINSIC
IGc2 9354 9422 9.26e-8 SMART
low complexity region 9506 9530 N/A INTRINSIC
IG 9550 9631 2.08e-1 SMART
IGc2 9645 9711 1.54e-4 SMART
IG 9728 9812 1.3e-11 SMART
low complexity region 9836 9868 N/A INTRINSIC
low complexity region 9871 9912 N/A INTRINSIC
low complexity region 9938 9955 N/A INTRINSIC
low complexity region 9958 9990 N/A INTRINSIC
low complexity region 10000 10036 N/A INTRINSIC
low complexity region 10049 10077 N/A INTRINSIC
low complexity region 10140 10150 N/A INTRINSIC
Pfam:PPAK 10198 10224 9.4e-8 PFAM
Pfam:PPAK 10255 10281 4e-10 PFAM
low complexity region 10282 10338 N/A INTRINSIC
low complexity region 10370 10416 N/A INTRINSIC
low complexity region 10428 10484 N/A INTRINSIC
Pfam:PPAK 10561 10587 3.5e-10 PFAM
low complexity region 10606 10725 N/A INTRINSIC
low complexity region 10761 10775 N/A INTRINSIC
Pfam:PPAK 10904 10930 1.3e-8 PFAM
Pfam:PPAK 10932 10958 1.4e-8 PFAM
Pfam:PPAK 10960 10986 2.8e-8 PFAM
low complexity region 11147 11280 N/A INTRINSIC
low complexity region 11299 11346 N/A INTRINSIC
low complexity region 11355 11368 N/A INTRINSIC
low complexity region 11369 11378 N/A INTRINSIC
low complexity region 11383 11416 N/A INTRINSIC
low complexity region 11419 11436 N/A INTRINSIC
Pfam:PPAK 11454 11480 7.1e-10 PFAM
low complexity region 11590 11603 N/A INTRINSIC
low complexity region 11647 11658 N/A INTRINSIC
low complexity region 11659 11683 N/A INTRINSIC
low complexity region 11700 11738 N/A INTRINSIC
Pfam:PPAK 11755 11781 9.1e-8 PFAM
Pfam:PPAK 11811 11837 8.9e-8 PFAM
low complexity region 11963 11979 N/A INTRINSIC
low complexity region 12044 12066 N/A INTRINSIC
low complexity region 12090 12109 N/A INTRINSIC
low complexity region 12137 12194 N/A INTRINSIC
Pfam:PPAK 12211 12237 9.1e-8 PFAM
Pfam:PPAK 12267 12293 8.9e-8 PFAM
low complexity region 12459 12570 N/A INTRINSIC
low complexity region 12583 12614 N/A INTRINSIC
low complexity region 12638 12681 N/A INTRINSIC
low complexity region 12691 12717 N/A INTRINSIC
low complexity region 12725 12741 N/A INTRINSIC
low complexity region 12746 12788 N/A INTRINSIC
low complexity region 12801 12818 N/A INTRINSIC
low complexity region 12824 12843 N/A INTRINSIC
low complexity region 12845 12859 N/A INTRINSIC
IGc2 12920 12986 3.85e-5 SMART
IG 13008 13090 4.49e-6 SMART
IG 13101 13189 1.1e0 SMART
IG_like 13192 13271 9.78e1 SMART
IG 13281 13359 5.45e-5 SMART
IG 13369 13448 3.08e-4 SMART
IG 13458 13536 1.93e-5 SMART
IG 13546 13625 1.81e-1 SMART
IG 13635 13721 9.49e-5 SMART
IG 13724 13803 2.94e-1 SMART
IG 13813 13901 4.29e-3 SMART
IG_like 13902 13981 7.3e1 SMART
IG 13991 14070 1.85e-7 SMART
IG 14080 14159 5.62e-7 SMART
IG 14169 14248 2.1e-6 SMART
IGc2 14264 14330 1.03e-5 SMART
IG 14347 14426 6.02e-7 SMART
IG 14435 14519 1e-3 SMART
IG 14529 14608 7.36e-2 SMART
IG 14618 14697 1.25e-4 SMART
IG 14707 14786 2.08e-1 SMART
IG 14795 14876 1.56e-5 SMART
FN3 14879 14962 1.85e-14 SMART
FN3 14980 15063 1.75e-15 SMART
FN3 15081 15164 4.44e-17 SMART
IG_like 15196 15263 1.79e0 SMART
FN3 15277 15359 7.73e-17 SMART
FN3 15377 15459 1.22e-14 SMART
IG 15486 15570 2.92e-5 SMART
FN3 15573 15655 4.08e-16 SMART
FN3 15672 15755 3.05e-15 SMART
FN3 15773 15855 1.09e-16 SMART
FN3 15873 15955 2.34e-16 SMART
FN3 15973 16056 3.7e-14 SMART
FN3 16074 16158 2.21e-12 SMART
IG 16182 16266 8.26e-5 SMART
FN3 16269 16351 1.15e-15 SMART
FN3 16369 16452 3.37e-17 SMART
IG 16475 16588 3.74e-3 SMART
FN3 16591 16675 7.62e-16 SMART
FN3 16692 16774 8.75e-16 SMART
FN3 16791 16874 1.95e-13 SMART
IG 16900 16983 3.79e-4 SMART
FN3 16986 17067 6.59e-11 SMART
FN3 17084 17167 3.7e-14 SMART
IGc2 17200 17273 2.21e-5 SMART
FN3 17287 17371 6.73e-17 SMART
FN3 17388 17476 4.95e-15 SMART
FN3 17494 17579 7.11e-16 SMART
IG 17606 17698 1.81e-1 SMART
FN3 17701 17783 3.81e-16 SMART
FN3 17801 17889 3.93e-18 SMART
IG 17912 18003 3.65e-6 SMART
FN3 18006 18089 2.19e-16 SMART
FN3 18106 18193 4.21e-18 SMART
FN3 18207 18293 5.95e-18 SMART
IG 18320 18402 5.28e-3 SMART
FN3 18405 18488 1.51e-10 SMART
FN3 18506 18589 2.34e-16 SMART
IG 18614 18698 2.5e-4 SMART
FN3 18701 18784 1.82e-13 SMART
FN3 18801 18884 6.73e-17 SMART
FN3 18902 18987 8.42e-18 SMART
IG 19014 19096 9.12e-7 SMART
FN3 19099 19181 1.14e-14 SMART
FN3 19199 19280 1.14e-14 SMART
IG 19306 19390 7.3e-6 SMART
FN3 19393 19476 2.19e-16 SMART
FN3 19493 19575 4.38e-16 SMART
FN3 19593 19677 4.88e-14 SMART
IGc2 19710 19777 1.44e-4 SMART
FN3 19791 19872 1.58e-13 SMART
FN3 19890 19973 6.05e-10 SMART
IG 19997 20083 9.12e-7 SMART
FN3 20086 20168 4.76e-17 SMART
FN3 20185 20268 1.14e-14 SMART
FN3 20286 20375 1.66e-16 SMART
IG 20402 20485 9.34e-4 SMART
FN3 20488 20570 6.14e-20 SMART
FN3 20588 20671 4.83e-18 SMART
IG 20694 20778 6.02e-7 SMART
FN3 20781 20864 2.44e-14 SMART
FN3 20881 20964 2.03e-11 SMART
FN3 20979 21064 7.06e-11 SMART
IG 21091 21175 2.44e-7 SMART
FN3 21178 21260 1.38e-13 SMART
FN3 21277 21360 4.69e-16 SMART
FN3 21378 21462 1.93e-17 SMART
IG 21489 21573 3.02e0 SMART
FN3 21576 21658 1.39e-18 SMART
FN3 21673 21753 5.69e-15 SMART
IG 21778 21862 7.08e-4 SMART
FN3 21865 21948 1.22e-14 SMART
FN3 21965 22048 3.5e-15 SMART
FN3 22063 22146 1.92e-12 SMART
IG 22174 22259 1.46e-5 SMART
FN3 22262 22344 1.2e-13 SMART
FN3 22361 22444 3.72e-19 SMART
FN3 22462 22546 1.38e-13 SMART
IG 22572 22654 8.59e-3 SMART
FN3 22657 22739 1.37e-17 SMART
FN3 22754 22835 7.5e-15 SMART
IG 22861 22945 1.81e-1 SMART
FN3 22948 23031 2.15e-15 SMART
FN3 23048 23131 5.31e-15 SMART
FN3 23146 23229 6.95e-10 SMART
IG 23257 23341 7.25e-1 SMART
FN3 23344 23427 8.75e-16 SMART
FN3 23444 23527 5.86e-17 SMART
FN3 23545 23629 4.31e-15 SMART
IG 23656 23738 4.78e-1 SMART
IG_like 23672 23727 1.79e0 SMART
FN3 23741 23823 1.02e-16 SMART
FN3 23838 23919 3.14e-17 SMART
IGc2 23949 24016 4.43e-5 SMART
FN3 24030 24113 3.22e-14 SMART
FN3 24130 24213 1.12e-13 SMART
FN3 24228 24311 1.58e-13 SMART
IG 24339 24423 6.97e-3 SMART
FN3 24426 24509 5.23e-14 SMART
FN3 24526 24609 3.05e-15 SMART
FN3 24627 24711 1.98e-14 SMART
IG 24738 24820 2.5e-4 SMART
FN3 24823 24905 2.69e-16 SMART
FN3 24920 25001 5.86e-17 SMART
IGc2 25031 25098 1.09e-4 SMART
FN3 25112 25195 2.07e-17 SMART
FN3 25212 25295 1.29e-13 SMART
FN3 25310 25393 2.33e-11 SMART
IG 25421 25505 8.72e-4 SMART
FN3 25508 25591 4.62e-15 SMART
FN3 25608 25691 1.47e-17 SMART
FN3 25709 25793 2.61e-14 SMART
IG 25820 25902 3.23e-7 SMART
FN3 25905 25987 1.22e-14 SMART
FN3 26002 26083 1.66e-16 SMART
IGc2 26113 26180 5.16e-6 SMART
FN3 26194 26277 1.88e-15 SMART
FN3 26294 26377 4.8e-13 SMART
FN3 26392 26476 6e-14 SMART
IG 26503 26588 2.08e0 SMART
FN3 26591 26674 2.04e-16 SMART
FN3 26691 26774 6.84e-18 SMART
FN3 26792 26876 1.9e-16 SMART
IG 26903 26985 2.3e-3 SMART
FN3 26988 27070 5.86e-17 SMART
FN3 27085 27166 1.17e-16 SMART
IG 27190 27274 2.08e-1 SMART
FN3 27277 27359 1.38e-13 SMART
FN3 27376 27459 3.64e-13 SMART
FN3 27474 27558 2.72e-12 SMART
IG 27585 27669 3.27e0 SMART
FN3 27672 27755 1.09e-11 SMART
FN3 27772 27855 6.53e-15 SMART
FN3 27873 27955 1.67e-12 SMART
IGc2 27988 28053 8.26e-5 SMART
FN3 28067 28149 2.8e-14 SMART
FN3 28164 28245 4.08e-16 SMART
IG 28272 28356 8.33e-1 SMART
FN3 28359 28442 1.42e-15 SMART
FN3 28459 28542 1.16e-11 SMART
FN3 28557 28640 4.31e-15 SMART
IG 28668 28752 4.16e-1 SMART
FN3 28755 28838 6.34e-13 SMART
FN3 28855 28938 4.24e-14 SMART
FN3 28956 29040 9.52e-17 SMART
IGc2 29073 29140 7.7e-5 SMART
FN3 29155 29237 9.99e-11 SMART
FN3 29252 29333 1.3e-9 SMART
IG 29359 29441 2.64e0 SMART
FN3 29446 29529 4.48e-13 SMART
FN3 29546 29629 1.72e-14 SMART
FN3 29644 29726 1.27e-12 SMART
IGc2 29760 29827 4.07e-4 SMART
FN3 29841 29924 2.46e-10 SMART
FN3 29941 30025 5.1e-17 SMART
FN3 30043 30126 2.93e-17 SMART
IG 30153 30235 2.03e-4 SMART
FN3 30238 30320 1.2e-13 SMART
FN3 30335 30416 2.48e-15 SMART
IG 30443 30527 2.18e-4 SMART
FN3 30530 30613 3.96e-14 SMART
FN3 30630 30713 9.75e-14 SMART
FN3 30728 30814 6.24e-12 SMART
IG 30843 30927 2.94e0 SMART
FN3 30930 31012 1.2e-13 SMART
FN3 31029 31113 1.07e-10 SMART
FN3 31131 31215 8.88e-17 SMART
IG 31242 31324 3.28e-8 SMART
FN3 31327 31409 5.07e-12 SMART
FN3 31424 31507 2.4e-13 SMART
IG 31534 31618 8.26e-5 SMART
FN3 31621 31704 1.44e-16 SMART
FN3 31721 31804 2.76e-13 SMART
FN3 31822 31905 6.63e-16 SMART
IG 31932 32012 5.66e-3 SMART
FN3 32017 32100 9.9e-15 SMART
FN3 32118 32202 9.16e-19 SMART
FN3 32220 32303 3.32e-16 SMART
IGc2 32334 32401 3.51e-8 SMART
IG 32424 32509 2.79e0 SMART
FN3 32512 32596 6.79e-13 SMART
FN3 32614 32697 3.7e-14 SMART
IG 32723 32809 1.85e-7 SMART
IG 32823 32908 1.55e0 SMART
FN3 32911 32992 1.33e-15 SMART
low complexity region 33014 33026 N/A INTRINSIC
S_TKc 33040 33294 9.98e-74 SMART
IG 33363 33448 7.36e-2 SMART
IG 33484 33571 1.78e-9 SMART
IG 33589 33674 1.11e-5 SMART
low complexity region 33860 33876 N/A INTRINSIC
low complexity region 33898 33910 N/A INTRINSIC
low complexity region 33912 33930 N/A INTRINSIC
low complexity region 34015 34025 N/A INTRINSIC
low complexity region 34031 34042 N/A INTRINSIC
low complexity region 34043 34065 N/A INTRINSIC
low complexity region 34094 34126 N/A INTRINSIC
IG 34169 34253 4.6e-3 SMART
IGc2 34362 34429 2.42e-11 SMART
IG 34510 34608 2.64e-3 SMART
IG_like 34521 34582 3.02e-1 SMART
IGc2 34653 34720 2.1e-6 SMART
IG 34834 34916 4.53e-2 SMART
IGc2 34935 35002 4.59e-12 SMART
low complexity region 35028 35047 N/A INTRINSIC
low complexity region 35051 35063 N/A INTRINSIC
low complexity region 35070 35098 N/A INTRINSIC
IG 35124 35211 8.51e-7 SMART
Predicted Effect probably damaging
Transcript: ENSMUST00000111846
AA Change: D29782A

PolyPhen 2 Score 0.993 (Sensitivity: 0.70; Specificity: 0.97)
SMART Domains Protein: ENSMUSP00000107477
Gene: ENSMUSG00000051747
AA Change: D29782A

DomainStartEndE-ValueType
IGc2 18 87 3.97e-7 SMART
IG 110 194 4.03e-8 SMART
low complexity region 251 270 N/A INTRINSIC
low complexity region 388 407 N/A INTRINSIC
Pfam:Titin_Z 412 454 1.3e-15 PFAM
Pfam:Titin_Z 463 504 6.4e-15 PFAM
Pfam:Titin_Z 509 548 2.4e-14 PFAM
Pfam:Titin_Z 553 594 7.8e-13 PFAM
Pfam:Titin_Z 599 640 8.2e-15 PFAM
Pfam:Titin_Z 645 686 1.3e-10 PFAM
Pfam:Titin_Z 690 732 2.3e-8 PFAM
low complexity region 931 947 N/A INTRINSIC
IGc2 958 1025 7.57e-13 SMART
IGc2 1096 1165 9.12e-7 SMART
low complexity region 1215 1223 N/A INTRINSIC
low complexity region 1269 1279 N/A INTRINSIC
IGc2 1305 1373 6.55e-8 SMART
low complexity region 1401 1420 N/A INTRINSIC
IG 1469 1554 8.72e-4 SMART
IG 1568 1656 1.63e-3 SMART
low complexity region 1703 1714 N/A INTRINSIC
IG_like 1715 1801 7.06e0 SMART
IG 1853 1936 7.94e-7 SMART
low complexity region 2034 2045 N/A INTRINSIC
low complexity region 2048 2062 N/A INTRINSIC
IG 2090 2175 6.51e-3 SMART
IG 2186 2269 1.81e-1 SMART
IG 2279 2358 1.34e-4 SMART
IG 2368 2449 2.94e0 SMART
IG 2457 2537 8.99e-6 SMART
IG 2545 2624 1.97e0 SMART
IG 2632 2711 2.18e-4 SMART
IG 2719 2799 5e0 SMART
IG 2807 2886 2.41e-6 SMART
IG 2894 2973 3.3e-4 SMART
IG 2981 3060 6.35e-6 SMART
IG 3070 3149 1.17e-4 SMART
IG 3159 3240 6.97e-3 SMART
IGc2 3257 3324 8.26e-5 SMART
low complexity region 3333 3342 N/A INTRINSIC
IG 3357 3440 1.66e-9 SMART
IGc2 3474 3541 6.02e-7 SMART
IGc2 3569 3636 1.69e-10 SMART
IGc2 3662 3729 5.79e-9 SMART
IGc2 3756 3823 3.5e-17 SMART
IGc2 3849 3916 2.92e-5 SMART
IGc2 3942 4009 1.7e-6 SMART
IG 4029 4113 2.83e-3 SMART
IGc2 4131 4198 2.35e-9 SMART
IGc2 4224 4291 4.82e-6 SMART
IGc2 4318 4385 7.13e-9 SMART
IG 4405 4489 9.34e-4 SMART
IG 4498 4582 1.32e-3 SMART
IG 4591 4675 5.75e-4 SMART
IGc2 4693 4760 3.03e-12 SMART
IGc2 4786 4853 2.68e-4 SMART
IGc2 4880 4947 1.47e-10 SMART
IGc2 4973 5040 2.28e-7 SMART
IGc2 5066 5133 3.76e-8 SMART
IGc2 5159 5226 1.31e-7 SMART
IGc2 5255 5322 2.44e-7 SMART
IG 5342 5423 2.71e0 SMART
IGc2 5430 5497 7.13e-9 SMART
IGc2 5523 5590 5.04e-9 SMART
IG 5610 5695 3.46e-7 SMART
IGc2 5710 5777 9.55e-10 SMART
IGc2 5806 5873 4.7e-9 SMART
IGc2 5899 5966 8.26e-5 SMART
IGc2 5992 6059 2.58e-6 SMART
IGc2 6085 6152 1.85e-16 SMART
IGc2 6181 6248 1.33e-8 SMART
IGc2 6277 6344 1.3e-11 SMART
IGc2 6371 6438 1.6e-11 SMART
IGc2 6464 6531 6.21e-9 SMART
IGc2 6557 6625 8.13e-4 SMART
IGc2 6651 6718 1.03e-5 SMART
IGc2 6747 6814 1.28e-10 SMART
IGc2 6840 6907 7.19e-5 SMART
IGc2 6933 7000 2.34e-4 SMART
IGc2 7026 7093 1.54e-13 SMART
IGc2 7122 7189 9.12e-7 SMART
IGc2 7218 7285 1.53e-8 SMART
IGc2 7312 7379 3.01e-7 SMART
IGc2 7405 7472 5.16e-6 SMART
IGc2 7498 7566 1.65e-4 SMART
IGc2 7592 7659 4.63e-8 SMART
IGc2 7688 7755 3.38e-10 SMART
IGc2 7781 7848 1.04e-10 SMART
IGc2 7874 7941 2.54e-5 SMART
IGc2 7967 8034 3.79e-13 SMART
IGc2 8063 8130 1.18e-9 SMART
IGc2 8159 8226 8e-12 SMART
IGc2 8256 8323 5.32e-8 SMART
IGc2 8352 8419 8.57e-12 SMART
low complexity region 8432 8443 N/A INTRINSIC
IGc2 8460 8528 9.26e-8 SMART
low complexity region 8612 8636 N/A INTRINSIC
IG 8656 8737 2.08e-1 SMART
IGc2 8751 8817 1.54e-4 SMART
IG 8834 8918 1.3e-11 SMART
low complexity region 8942 8974 N/A INTRINSIC
low complexity region 8977 9021 N/A INTRINSIC
low complexity region 9047 9064 N/A INTRINSIC
low complexity region 9067 9099 N/A INTRINSIC
low complexity region 9109 9145 N/A INTRINSIC
low complexity region 9158 9186 N/A INTRINSIC
low complexity region 9249 9259 N/A INTRINSIC
Pfam:PPAK 9307 9334 2.4e-8 PFAM
Pfam:PPAK 9364 9390 3.6e-10 PFAM
low complexity region 9391 9447 N/A INTRINSIC
low complexity region 9479 9525 N/A INTRINSIC
low complexity region 9537 9593 N/A INTRINSIC
Pfam:PPAK 9614 9641 4e-10 PFAM
Pfam:PPAK 9670 9697 1.5e-9 PFAM
low complexity region 9715 9834 N/A INTRINSIC
Pfam:PPAK 10046 10073 4.6e-8 PFAM
Pfam:PPAK 10074 10101 2.4e-8 PFAM
Pfam:PPAK 10102 10129 1.4e-9 PFAM
low complexity region 10263 10403 N/A INTRINSIC
low complexity region 10422 10469 N/A INTRINSIC
low complexity region 10478 10491 N/A INTRINSIC
low complexity region 10492 10501 N/A INTRINSIC
low complexity region 10506 10539 N/A INTRINSIC
Pfam:PPAK 10599 10626 6.1e-8 PFAM
Pfam:PPAK 10683 10710 1.5e-7 PFAM
low complexity region 10847 10935 N/A INTRINSIC
low complexity region 10945 10971 N/A INTRINSIC
low complexity region 10979 10995 N/A INTRINSIC
low complexity region 11000 11042 N/A INTRINSIC
low complexity region 11055 11072 N/A INTRINSIC
low complexity region 11078 11097 N/A INTRINSIC
low complexity region 11099 11113 N/A INTRINSIC
IGc2 11174 11240 3.85e-5 SMART
IG 11262 11344 4.49e-6 SMART
IG 11355 11443 1.1e0 SMART
IG_like 11446 11525 9.78e1 SMART
IG 11535 11613 5.45e-5 SMART
IG 11623 11702 3.08e-4 SMART
IG 11712 11790 1.93e-5 SMART
IG 11800 11879 1.81e-1 SMART
IG 11889 11975 9.49e-5 SMART
IG 11978 12057 2.94e-1 SMART
IG 12067 12155 4.29e-3 SMART
IG_like 12156 12235 7.3e1 SMART
IG 12245 12324 1.85e-7 SMART
IG 12334 12413 5.62e-7 SMART
IG 12423 12502 2.1e-6 SMART
IGc2 12518 12584 1.03e-5 SMART
IG 12601 12680 6.02e-7 SMART
IG 12689 12773 1e-3 SMART
IG 12783 12862 7.36e-2 SMART
IG 12872 12951 1.25e-4 SMART
IG 12961 13040 2.08e-1 SMART
IG 13049 13130 1.56e-5 SMART
FN3 13133 13216 1.85e-14 SMART
FN3 13234 13317 1.75e-15 SMART
FN3 13335 13418 4.44e-17 SMART
IG_like 13450 13517 1.79e0 SMART
FN3 13531 13613 7.73e-17 SMART
FN3 13631 13713 1.22e-14 SMART
IG 13740 13824 2.92e-5 SMART
FN3 13827 13909 4.08e-16 SMART
FN3 13926 14009 3.05e-15 SMART
FN3 14027 14109 1.09e-16 SMART
FN3 14127 14209 2.34e-16 SMART
FN3 14227 14310 3.7e-14 SMART
FN3 14328 14412 2.21e-12 SMART
IG 14436 14520 8.26e-5 SMART
FN3 14523 14605 1.15e-15 SMART
FN3 14623 14706 3.37e-17 SMART
IG 14729 14842 3.74e-3 SMART
FN3 14845 14929 7.62e-16 SMART
FN3 14946 15028 8.75e-16 SMART
FN3 15045 15128 1.95e-13 SMART
IG 15154 15237 3.79e-4 SMART
FN3 15240 15321 6.59e-11 SMART
FN3 15338 15421 3.7e-14 SMART
IGc2 15454 15527 2.21e-5 SMART
FN3 15541 15625 6.73e-17 SMART
FN3 15642 15730 4.95e-15 SMART
FN3 15748 15833 7.11e-16 SMART
IG 15860 15952 1.81e-1 SMART
FN3 15955 16037 3.81e-16 SMART
FN3 16055 16143 3.93e-18 SMART
IG 16166 16257 3.65e-6 SMART
FN3 16260 16343 2.19e-16 SMART
FN3 16360 16447 4.21e-18 SMART
FN3 16461 16547 5.95e-18 SMART
IG 16574 16656 5.28e-3 SMART
FN3 16659 16742 1.51e-10 SMART
FN3 16760 16843 2.34e-16 SMART
IG 16868 16952 2.5e-4 SMART
FN3 16955 17038 1.82e-13 SMART
FN3 17055 17138 6.73e-17 SMART
FN3 17156 17241 8.42e-18 SMART
IG 17268 17350 9.12e-7 SMART
FN3 17353 17435 1.14e-14 SMART
FN3 17453 17534 1.14e-14 SMART
IG 17560 17644 7.3e-6 SMART
FN3 17647 17730 2.19e-16 SMART
FN3 17747 17829 4.38e-16 SMART
FN3 17847 17931 4.88e-14 SMART
IGc2 17964 18031 1.44e-4 SMART
FN3 18045 18126 1.58e-13 SMART
FN3 18144 18227 6.05e-10 SMART
IG 18251 18337 9.12e-7 SMART
FN3 18340 18422 4.76e-17 SMART
FN3 18439 18522 1.14e-14 SMART
FN3 18540 18629 1.66e-16 SMART
IG 18656 18739 9.34e-4 SMART
FN3 18742 18824 6.14e-20 SMART
FN3 18842 18925 4.83e-18 SMART
IG 18948 19032 6.02e-7 SMART
FN3 19035 19118 2.44e-14 SMART
FN3 19135 19218 2.03e-11 SMART
FN3 19233 19318 7.06e-11 SMART
IG 19345 19429 2.44e-7 SMART
FN3 19432 19514 1.38e-13 SMART
FN3 19531 19614 4.69e-16 SMART
FN3 19632 19716 1.93e-17 SMART
IG 19743 19827 3.02e0 SMART
FN3 19830 19912 1.39e-18 SMART
FN3 19927 20007 5.69e-15 SMART
IG 20032 20116 7.08e-4 SMART
FN3 20119 20202 1.22e-14 SMART
FN3 20219 20302 3.5e-15 SMART
FN3 20317 20400 1.92e-12 SMART
IG 20428 20513 1.46e-5 SMART
FN3 20516 20598 1.2e-13 SMART
FN3 20615 20698 3.72e-19 SMART
FN3 20716 20800 1.38e-13 SMART
IG 20826 20908 8.59e-3 SMART
FN3 20911 20993 1.37e-17 SMART
FN3 21008 21089 7.5e-15 SMART
IG 21115 21199 1.81e-1 SMART
FN3 21202 21285 2.15e-15 SMART
FN3 21302 21385 5.31e-15 SMART
FN3 21400 21483 6.95e-10 SMART
IG 21511 21595 7.25e-1 SMART
FN3 21598 21681 8.75e-16 SMART
FN3 21698 21781 5.86e-17 SMART
FN3 21799 21883 4.31e-15 SMART
IG 21910 21992 4.78e-1 SMART
IG_like 21926 21981 1.79e0 SMART
FN3 21995 22077 1.02e-16 SMART
FN3 22092 22173 3.14e-17 SMART
IGc2 22203 22270 4.43e-5 SMART
FN3 22284 22367 3.22e-14 SMART
FN3 22384 22467 1.12e-13 SMART
FN3 22482 22565 1.58e-13 SMART
IG 22593 22677 6.97e-3 SMART
FN3 22680 22763 5.23e-14 SMART
FN3 22780 22863 3.05e-15 SMART
FN3 22881 22965 1.98e-14 SMART
IG 22992 23074 2.5e-4 SMART
FN3 23077 23159 2.69e-16 SMART
FN3 23174 23255 5.86e-17 SMART
IGc2 23285 23352 1.09e-4 SMART
FN3 23366 23449 2.07e-17 SMART
FN3 23466 23549 1.29e-13 SMART
FN3 23564 23647 2.33e-11 SMART
IG 23675 23759 8.72e-4 SMART
FN3 23762 23845 4.62e-15 SMART
FN3 23862 23945 1.47e-17 SMART
FN3 23963 24047 2.61e-14 SMART
IG 24074 24156 3.23e-7 SMART
FN3 24159 24241 1.22e-14 SMART
FN3 24256 24337 1.66e-16 SMART
IGc2 24367 24434 5.16e-6 SMART
FN3 24448 24531 1.88e-15 SMART
FN3 24548 24631 4.8e-13 SMART
FN3 24646 24730 6e-14 SMART
IG 24757 24842 2.08e0 SMART
FN3 24845 24928 2.04e-16 SMART
FN3 24945 25028 6.84e-18 SMART
FN3 25046 25130 1.9e-16 SMART
IG 25157 25239 2.3e-3 SMART
FN3 25242 25324 5.86e-17 SMART
FN3 25339 25420 1.17e-16 SMART
IG 25444 25528 2.08e-1 SMART
FN3 25531 25613 1.38e-13 SMART
FN3 25630 25713 3.64e-13 SMART
FN3 25728 25812 2.72e-12 SMART
IG 25839 25923 3.27e0 SMART
FN3 25926 26009 1.09e-11 SMART
FN3 26026 26109 6.53e-15 SMART
FN3 26127 26209 1.67e-12 SMART
IGc2 26242 26307 8.26e-5 SMART
FN3 26321 26403 2.8e-14 SMART
FN3 26418 26499 4.08e-16 SMART
IG 26526 26610 8.33e-1 SMART
FN3 26613 26696 1.42e-15 SMART
FN3 26713 26796 1.16e-11 SMART
FN3 26811 26894 4.31e-15 SMART
IG 26922 27006 4.16e-1 SMART
FN3 27009 27092 6.34e-13 SMART
FN3 27109 27192 4.24e-14 SMART
FN3 27210 27294 9.52e-17 SMART
IGc2 27327 27394 7.7e-5 SMART
FN3 27409 27491 9.99e-11 SMART
FN3 27506 27587 1.3e-9 SMART
IG 27613 27695 2.64e0 SMART
FN3 27700 27783 4.48e-13 SMART
FN3 27800 27883 1.72e-14 SMART
FN3 27898 27980 1.27e-12 SMART
IGc2 28014 28081 4.07e-4 SMART
FN3 28095 28178 2.46e-10 SMART
FN3 28195 28279 5.1e-17 SMART
FN3 28297 28380 2.93e-17 SMART
IG 28407 28489 2.03e-4 SMART
FN3 28492 28574 1.2e-13 SMART
FN3 28589 28670 2.48e-15 SMART
IG 28697 28781 2.18e-4 SMART
FN3 28784 28867 3.96e-14 SMART
FN3 28884 28967 9.75e-14 SMART
FN3 28982 29068 6.24e-12 SMART
IG 29097 29181 2.94e0 SMART
FN3 29184 29266 1.2e-13 SMART