Incidental Mutation 'R7447:Clip1'
| ID |
577350 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Clip1
|
| Ensembl Gene |
ENSMUSG00000049550 |
| Gene Name |
CAP-GLY domain containing linker protein 1 |
| Synonyms |
Rsn, CLIP-170, 4631429H07Rik, restin, Clip 170, 1110007I12Rik, Clip50, cytoplasmic linker protein 50 |
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7447 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
5 |
| Chromosomal Location |
123715857-123822527 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 123791696 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Phenylalanine
at position 158
(S158F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000107190
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000031382]
[ENSMUST00000063905]
[ENSMUST00000111561]
[ENSMUST00000111564]
[ENSMUST00000111566]
[ENSMUST00000149410]
|
| AlphaFold |
Q922J3 |
| PDB Structure |
Solution structure of the 1st CAP-Gly domain in mouse CLIP-170/restin [SOLUTION NMR]
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000031382
AA Change: S158F
PolyPhen 2
Score 0.592 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000031382
Gene: ENSMUSG00000049550
AA Change: S158F
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
2.28e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
2.28e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
451 |
N/A |
INTRINSIC |
|
coiled coil region
|
474 |
535 |
N/A |
INTRINSIC |
|
coiled coil region
|
581 |
620 |
N/A |
INTRINSIC |
|
coiled coil region
|
652 |
1352 |
N/A |
INTRINSIC |
|
low complexity region
|
1362 |
1373 |
N/A |
INTRINSIC |
|
Pfam:CLIP1_ZNF
|
1375 |
1392 |
5.8e-9 |
PFAM |
|
ZnF_C2HC
|
1417 |
1433 |
1.45e0 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000063905
AA Change: S158F
PolyPhen 2
Score 0.641 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000068241
Gene: ENSMUSG00000049550
AA Change: S158F
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
3.3e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
3.3e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
524 |
N/A |
INTRINSIC |
|
coiled coil region
|
570 |
609 |
N/A |
INTRINSIC |
|
coiled coil region
|
641 |
1075 |
N/A |
INTRINSIC |
|
coiled coil region
|
1115 |
1235 |
N/A |
INTRINSIC |
|
low complexity region
|
1245 |
1256 |
N/A |
INTRINSIC |
|
ZnF_C2HC
|
1300 |
1316 |
1.45e0 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000111561
AA Change: S158F
PolyPhen 2
Score 0.598 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000107186
Gene: ENSMUSG00000049550
AA Change: S158F
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
1.93e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
1.93e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
524 |
N/A |
INTRINSIC |
|
coiled coil region
|
570 |
609 |
N/A |
INTRINSIC |
|
coiled coil region
|
641 |
1341 |
N/A |
INTRINSIC |
|
low complexity region
|
1351 |
1362 |
N/A |
INTRINSIC |
|
ZnF_C2HC
|
1406 |
1422 |
1.45e0 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000111564
AA Change: S158F
PolyPhen 2
Score 0.034 (Sensitivity: 0.95; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000107190
Gene: ENSMUSG00000049550
AA Change: S158F
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
2.5e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
2.5e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
489 |
N/A |
INTRINSIC |
|
coiled coil region
|
535 |
574 |
N/A |
INTRINSIC |
|
coiled coil region
|
606 |
1230 |
N/A |
INTRINSIC |
|
low complexity region
|
1240 |
1251 |
N/A |
INTRINSIC |
|
ZnF_C2HC
|
1295 |
1311 |
1.45e0 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000111566
AA Change: S158F
PolyPhen 2
Score 0.870 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000107192
Gene: ENSMUSG00000049550
AA Change: S158F
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
2e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
2e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
489 |
N/A |
INTRINSIC |
|
coiled coil region
|
535 |
574 |
N/A |
INTRINSIC |
|
coiled coil region
|
606 |
1306 |
N/A |
INTRINSIC |
|
low complexity region
|
1316 |
1327 |
N/A |
INTRINSIC |
|
ZnF_C2HC
|
1371 |
1387 |
1.45e0 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000144121
AA Change: S134F
PolyPhen 2
Score 0.651 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000119641
Gene: ENSMUSG00000049550
AA Change: S134F
| Domain | Start | End | E-Value | Type |
|---|
|
CAP_GLY
|
37 |
102 |
1.05e-31 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000149410
AA Change: S158F
PolyPhen 2
Score 0.924 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000115965
Gene: ENSMUSG00000049550
AA Change: S158F
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
26 |
32 |
N/A |
INTRINSIC |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
334 |
458 |
N/A |
INTRINSIC |
|
coiled coil region
|
504 |
543 |
N/A |
INTRINSIC |
|
coiled coil region
|
575 |
827 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.4%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene links endocytic vesicles to microtubules. This gene is highly expressed in Reed-Sternberg cells of Hodgkin disease. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
PHENOTYPE: Mice homozygous for a targeted allele display reduced male fertility and teratozoospermia. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 88 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adck5 |
A |
T |
15: 76,479,396 (GRCm39) |
I484F |
possibly damaging |
Het |
| Ago2 |
A |
T |
15: 73,009,881 (GRCm39) |
N100K |
probably benign |
Het |
| Appl1 |
T |
A |
14: 26,681,409 (GRCm39) |
K130* |
probably null |
Het |
| Arhgap39 |
G |
A |
15: 76,649,797 (GRCm39) |
|
probably benign |
Het |
| Axdnd1 |
A |
G |
1: 156,245,802 (GRCm39) |
|
probably null |
Het |
| Camta1 |
A |
T |
4: 151,168,327 (GRCm39) |
V1332E |
probably benign |
Het |
| Cd3g |
A |
G |
9: 44,884,857 (GRCm39) |
L129P |
probably damaging |
Het |
| Cd80 |
T |
G |
16: 38,294,251 (GRCm39) |
S45A |
probably benign |
Het |
| Cdk12 |
A |
T |
11: 98,136,106 (GRCm39) |
Q1120L |
unknown |
Het |
| Cntn3 |
C |
A |
6: 102,255,416 (GRCm39) |
E161* |
probably null |
Het |
| Cyp3a59 |
A |
C |
5: 146,024,215 (GRCm39) |
K67T |
probably benign |
Het |
| Dmxl1 |
T |
C |
18: 49,997,681 (GRCm39) |
L623P |
probably damaging |
Het |
| Drd3 |
T |
A |
16: 43,637,426 (GRCm39) |
Y208* |
probably null |
Het |
| Dusp10 |
A |
T |
1: 183,801,153 (GRCm39) |
M307L |
probably benign |
Het |
| Dync2li1 |
A |
T |
17: 84,955,141 (GRCm39) |
I267L |
possibly damaging |
Het |
| Dynlt2b |
T |
A |
16: 32,244,089 (GRCm39) |
V95E |
probably damaging |
Het |
| Edn3 |
C |
A |
2: 174,603,544 (GRCm39) |
C97* |
probably null |
Het |
| Ehbp1l1 |
T |
A |
19: 5,769,456 (GRCm39) |
T616S |
possibly damaging |
Het |
| Eif2a |
C |
T |
3: 58,452,963 (GRCm39) |
T246I |
probably damaging |
Het |
| Enpp5 |
G |
A |
17: 44,396,155 (GRCm39) |
G356S |
probably damaging |
Het |
| Errfi1 |
A |
G |
4: 150,951,108 (GRCm39) |
T179A |
probably damaging |
Het |
| Esyt3 |
G |
A |
9: 99,203,615 (GRCm39) |
L450F |
probably damaging |
Het |
| Evx2 |
A |
G |
2: 74,489,448 (GRCm39) |
S106P |
probably benign |
Het |
| Fam83a |
T |
G |
15: 57,873,086 (GRCm39) |
V305G |
probably benign |
Het |
| Fem1al |
T |
C |
11: 29,774,122 (GRCm39) |
D445G |
probably benign |
Het |
| Gpr171 |
T |
A |
3: 59,005,860 (GRCm39) |
|
probably null |
Het |
| Grip1 |
A |
G |
10: 119,922,871 (GRCm39) |
T1106A |
probably benign |
Het |
| Hecw1 |
A |
G |
13: 14,531,789 (GRCm39) |
Y162H |
probably damaging |
Het |
| Hephl1 |
C |
T |
9: 15,009,178 (GRCm39) |
|
probably null |
Het |
| Hsp90aa1 |
A |
G |
12: 110,658,562 (GRCm39) |
I693T |
possibly damaging |
Het |
| Ifit1bl2 |
T |
A |
19: 34,596,974 (GRCm39) |
D214V |
probably damaging |
Het |
| Igsf10 |
T |
C |
3: 59,239,222 (GRCm39) |
M320V |
probably benign |
Het |
| Kcnq2 |
A |
G |
2: 180,754,887 (GRCm39) |
L220P |
probably damaging |
Het |
| Kpna1 |
C |
A |
16: 35,850,009 (GRCm39) |
Q372K |
probably damaging |
Het |
| Lilrb4a |
T |
G |
10: 51,367,149 (GRCm39) |
|
probably null |
Het |
| Ly75 |
C |
A |
2: 60,164,818 (GRCm39) |
E787* |
probably null |
Het |
| Magi1 |
T |
G |
6: 93,722,562 (GRCm39) |
S666R |
possibly damaging |
Het |
| Mif |
C |
A |
10: 75,695,687 (GRCm39) |
A39S |
possibly damaging |
Het |
| Mob4 |
G |
A |
1: 55,170,625 (GRCm39) |
|
probably benign |
Het |
| Mtmr4 |
G |
T |
11: 87,502,727 (GRCm39) |
C927F |
probably damaging |
Het |
| Myh1 |
A |
G |
11: 67,110,006 (GRCm39) |
K1398R |
probably benign |
Het |
| Myo3a |
T |
C |
2: 22,436,464 (GRCm39) |
V873A |
probably benign |
Het |
| Naip5 |
T |
C |
13: 100,356,204 (GRCm39) |
Q1137R |
probably benign |
Het |
| Naip5 |
G |
T |
13: 100,356,205 (GRCm39) |
Q1137K |
not run |
Het |
| Nckap5l |
G |
A |
15: 99,325,357 (GRCm39) |
P382L |
probably damaging |
Het |
| Ngly1 |
T |
C |
14: 16,290,844 (GRCm38) |
I442T |
probably damaging |
Het |
| Nhsl3 |
C |
A |
4: 129,115,835 (GRCm39) |
R988L |
possibly damaging |
Het |
| Nlrp1a |
T |
C |
11: 70,983,237 (GRCm39) |
Y1243C |
probably damaging |
Het |
| Or8k53 |
T |
A |
2: 86,177,150 (GRCm39) |
H320L |
possibly damaging |
Het |
| Pcsk5 |
C |
T |
19: 17,487,600 (GRCm39) |
G1027D |
probably benign |
Het |
| Pla2g2c |
T |
A |
4: 138,458,927 (GRCm39) |
I11N |
probably benign |
Het |
| Polr3d |
A |
G |
14: 70,677,240 (GRCm39) |
I331T |
probably damaging |
Het |
| Ppp4r4 |
A |
G |
12: 103,551,985 (GRCm39) |
I293M |
possibly damaging |
Het |
| Prkce |
G |
T |
17: 86,866,687 (GRCm39) |
V516F |
probably damaging |
Het |
| Prss27 |
T |
A |
17: 24,264,683 (GRCm39) |
L282Q |
probably damaging |
Het |
| Pxdn |
A |
G |
12: 30,034,926 (GRCm39) |
Y261C |
probably damaging |
Het |
| R3hcc1l |
T |
C |
19: 42,551,101 (GRCm39) |
S33P |
probably benign |
Het |
| Rab11fip3 |
G |
C |
17: 26,287,848 (GRCm39) |
R102G |
possibly damaging |
Het |
| Rabggta |
A |
T |
14: 55,956,773 (GRCm39) |
N310K |
probably null |
Het |
| Rbbp8 |
T |
A |
18: 11,793,934 (GRCm39) |
D15E |
probably benign |
Het |
| Rbm5 |
T |
C |
9: 107,623,378 (GRCm39) |
Y486C |
probably damaging |
Het |
| Rptor |
T |
A |
11: 119,775,805 (GRCm39) |
F992Y |
probably benign |
Het |
| Slc29a2 |
T |
G |
19: 5,076,445 (GRCm39) |
L111R |
probably damaging |
Het |
| Slc39a11 |
T |
A |
11: 113,452,849 (GRCm39) |
I31L |
probably benign |
Het |
| Slc6a20a |
T |
A |
9: 123,485,289 (GRCm39) |
N311I |
possibly damaging |
Het |
| Slc8a1 |
A |
G |
17: 81,956,435 (GRCm39) |
F201S |
probably damaging |
Het |
| Smtn |
C |
A |
11: 3,480,196 (GRCm39) |
V342L |
probably benign |
Het |
| Syne2 |
A |
G |
12: 76,074,853 (GRCm39) |
T4598A |
probably benign |
Het |
| Tchp |
A |
G |
5: 114,853,716 (GRCm39) |
T267A |
probably benign |
Het |
| Tes3-ps |
A |
G |
13: 49,647,508 (GRCm39) |
E128G |
possibly damaging |
Het |
| Tigar |
C |
T |
6: 127,065,129 (GRCm39) |
G173E |
probably benign |
Het |
| Tmem171 |
T |
C |
13: 98,824,862 (GRCm39) |
N256S |
probably benign |
Het |
| Tmem204 |
A |
G |
17: 25,277,270 (GRCm39) |
I205T |
probably damaging |
Het |
| Tmem63a |
A |
G |
1: 180,785,588 (GRCm39) |
K240R |
probably benign |
Het |
| Tns2 |
C |
T |
15: 102,019,351 (GRCm39) |
T446M |
probably damaging |
Het |
| Tnxb |
A |
T |
17: 34,937,444 (GRCm39) |
N2931I |
probably damaging |
Het |
| Trrap |
G |
T |
5: 144,776,284 (GRCm39) |
R2941L |
probably damaging |
Het |
| Ttc8 |
A |
T |
12: 98,910,131 (GRCm39) |
R179S |
probably damaging |
Het |
| Ttll12 |
G |
T |
15: 83,471,176 (GRCm39) |
T234N |
probably damaging |
Het |
| Ttn |
G |
T |
2: 76,577,576 (GRCm39) |
T24439K |
probably damaging |
Het |
| Ube2z |
A |
T |
11: 95,946,736 (GRCm39) |
I246N |
possibly damaging |
Het |
| Usp15 |
A |
G |
10: 123,011,786 (GRCm39) |
Y104H |
probably damaging |
Het |
| Usp29 |
A |
C |
7: 6,964,219 (GRCm39) |
T21P |
possibly damaging |
Het |
| Usp5 |
G |
A |
6: 124,798,077 (GRCm39) |
A436V |
probably damaging |
Het |
| Utp20 |
A |
G |
10: 88,608,354 (GRCm39) |
L1561S |
probably damaging |
Het |
| Xrn1 |
A |
G |
9: 95,927,547 (GRCm39) |
M1444V |
probably benign |
Het |
| Zfp236 |
G |
T |
18: 82,651,815 (GRCm39) |
Q885K |
probably damaging |
Het |
| Zfp831 |
C |
A |
2: 174,487,896 (GRCm39) |
P857Q |
possibly damaging |
Het |
|
| Other mutations in Clip1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00159:Clip1
|
APN |
5 |
123,741,717 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01067:Clip1
|
APN |
5 |
123,768,867 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01524:Clip1
|
APN |
5 |
123,717,442 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01632:Clip1
|
APN |
5 |
123,755,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01798:Clip1
|
APN |
5 |
123,721,612 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01874:Clip1
|
APN |
5 |
123,741,729 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
IGL01908:Clip1
|
APN |
5 |
123,761,270 (GRCm39) |
splice site |
probably benign |
|
|
IGL02120:Clip1
|
APN |
5 |
123,785,946 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02309:Clip1
|
APN |
5 |
123,755,763 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02555:Clip1
|
APN |
5 |
123,759,857 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03027:Clip1
|
APN |
5 |
123,759,919 (GRCm39) |
missense |
probably benign |
0.43 |
|
IGL03336:Clip1
|
APN |
5 |
123,791,633 (GRCm39) |
nonsense |
probably null |
|
|
IGL03365:Clip1
|
APN |
5 |
123,721,649 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02802:Clip1
|
UTSW |
5 |
123,769,186 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4812001:Clip1
|
UTSW |
5 |
123,768,738 (GRCm39) |
missense |
probably benign |
0.08 |
|
R0254:Clip1
|
UTSW |
5 |
123,755,395 (GRCm39) |
splice site |
probably benign |
|
|
R0401:Clip1
|
UTSW |
5 |
123,791,852 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0530:Clip1
|
UTSW |
5 |
123,778,594 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0744:Clip1
|
UTSW |
5 |
123,768,784 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0833:Clip1
|
UTSW |
5 |
123,768,784 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1116:Clip1
|
UTSW |
5 |
123,717,554 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1182:Clip1
|
UTSW |
5 |
123,785,928 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1656:Clip1
|
UTSW |
5 |
123,768,466 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R1700:Clip1
|
UTSW |
5 |
123,768,433 (GRCm39) |
missense |
probably benign |
|
|
R1889:Clip1
|
UTSW |
5 |
123,791,559 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1975:Clip1
|
UTSW |
5 |
123,761,281 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2406:Clip1
|
UTSW |
5 |
123,741,723 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3545:Clip1
|
UTSW |
5 |
123,769,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3547:Clip1
|
UTSW |
5 |
123,769,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3548:Clip1
|
UTSW |
5 |
123,769,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3911:Clip1
|
UTSW |
5 |
123,728,897 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3944:Clip1
|
UTSW |
5 |
123,755,892 (GRCm39) |
unclassified |
probably benign |
|
|
R4660:Clip1
|
UTSW |
5 |
123,717,437 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4784:Clip1
|
UTSW |
5 |
123,717,356 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4785:Clip1
|
UTSW |
5 |
123,717,356 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4824:Clip1
|
UTSW |
5 |
123,769,086 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4831:Clip1
|
UTSW |
5 |
123,721,664 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4951:Clip1
|
UTSW |
5 |
123,768,408 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4960:Clip1
|
UTSW |
5 |
123,792,066 (GRCm39) |
nonsense |
probably null |
|
|
R5014:Clip1
|
UTSW |
5 |
123,755,793 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5116:Clip1
|
UTSW |
5 |
123,768,770 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5212:Clip1
|
UTSW |
5 |
123,768,744 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5238:Clip1
|
UTSW |
5 |
123,785,946 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5318:Clip1
|
UTSW |
5 |
123,751,147 (GRCm39) |
unclassified |
probably benign |
|
|
R5372:Clip1
|
UTSW |
5 |
123,768,303 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5701:Clip1
|
UTSW |
5 |
123,751,366 (GRCm39) |
unclassified |
probably benign |
|
|
R5734:Clip1
|
UTSW |
5 |
123,753,217 (GRCm39) |
unclassified |
probably benign |
|
|
R5757:Clip1
|
UTSW |
5 |
123,765,460 (GRCm39) |
missense |
probably benign |
0.21 |
|
R6024:Clip1
|
UTSW |
5 |
123,753,152 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R6160:Clip1
|
UTSW |
5 |
123,751,604 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R6177:Clip1
|
UTSW |
5 |
123,751,897 (GRCm39) |
unclassified |
probably benign |
|
|
R6183:Clip1
|
UTSW |
5 |
123,780,667 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6377:Clip1
|
UTSW |
5 |
123,741,717 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R6436:Clip1
|
UTSW |
5 |
123,779,848 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6471:Clip1
|
UTSW |
5 |
123,778,612 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6766:Clip1
|
UTSW |
5 |
123,752,827 (GRCm39) |
unclassified |
probably benign |
|
|
R7015:Clip1
|
UTSW |
5 |
123,751,675 (GRCm39) |
unclassified |
probably benign |
|
|
R7094:Clip1
|
UTSW |
5 |
123,761,333 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7143:Clip1
|
UTSW |
5 |
123,791,673 (GRCm39) |
missense |
probably benign |
|
|
R7222:Clip1
|
UTSW |
5 |
123,749,904 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7233:Clip1
|
UTSW |
5 |
123,749,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7238:Clip1
|
UTSW |
5 |
123,751,328 (GRCm39) |
missense |
|
|
|
R7249:Clip1
|
UTSW |
5 |
123,741,663 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7283:Clip1
|
UTSW |
5 |
123,751,857 (GRCm39) |
missense |
|
|
|
R7295:Clip1
|
UTSW |
5 |
123,765,419 (GRCm39) |
missense |
probably benign |
0.19 |
|
R7458:Clip1
|
UTSW |
5 |
123,778,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7483:Clip1
|
UTSW |
5 |
123,755,447 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7516:Clip1
|
UTSW |
5 |
123,721,448 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7619:Clip1
|
UTSW |
5 |
123,752,342 (GRCm39) |
missense |
|
|
|
R7831:Clip1
|
UTSW |
5 |
123,751,342 (GRCm39) |
missense |
|
|
|
R7897:Clip1
|
UTSW |
5 |
123,760,861 (GRCm39) |
missense |
probably benign |
|
|
R8155:Clip1
|
UTSW |
5 |
123,751,699 (GRCm39) |
missense |
|
|
|
R8157:Clip1
|
UTSW |
5 |
123,768,782 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8232:Clip1
|
UTSW |
5 |
123,785,981 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8396:Clip1
|
UTSW |
5 |
123,780,627 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8446:Clip1
|
UTSW |
5 |
123,794,008 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8486:Clip1
|
UTSW |
5 |
123,752,770 (GRCm39) |
unclassified |
probably benign |
|
|
R8511:Clip1
|
UTSW |
5 |
123,791,969 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R8731:Clip1
|
UTSW |
5 |
123,752,756 (GRCm39) |
missense |
|
|
|
R8889:Clip1
|
UTSW |
5 |
123,717,565 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8892:Clip1
|
UTSW |
5 |
123,717,565 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9058:Clip1
|
UTSW |
5 |
123,752,645 (GRCm39) |
missense |
|
|
|
R9106:Clip1
|
UTSW |
5 |
123,753,223 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9212:Clip1
|
UTSW |
5 |
123,721,399 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9217:Clip1
|
UTSW |
5 |
123,717,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9223:Clip1
|
UTSW |
5 |
123,784,337 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9325:Clip1
|
UTSW |
5 |
123,751,186 (GRCm39) |
missense |
|
|
|
R9752:Clip1
|
UTSW |
5 |
123,760,009 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Clip1
|
UTSW |
5 |
123,755,413 (GRCm39) |
missense |
probably damaging |
0.99 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTCTCTCAAGGGGAAGGAGG -3'
(R):5'- AAGAACGATGGCTCTGTGGC -3'
Sequencing Primer
(F):5'- AGTGGCCAGTGACTCACCAG -3'
(R):5'- CGGGAGTGCGGTATTTCCAG -3'
|
| Posted On |
2019-10-07 |
Incidental Mutation