Incidental Mutation 'R7447:Zfp236'
| ID |
577413 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Zfp236
|
| Ensembl Gene |
ENSMUSG00000041258 |
| Gene Name |
zinc finger protein 236 |
| Synonyms |
LOC240456 |
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R7447 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
18 |
| Chromosomal Location |
82611718-82711008 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to T
at 82651815 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamine to Lysine
at position 885
(Q885K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000138557
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000171071]
[ENSMUST00000182122]
[ENSMUST00000183048]
|
| AlphaFold |
S4R299 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000171071
AA Change: Q837K
PolyPhen 2
Score 0.991 (Sensitivity: 0.71; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000130004
Gene: ENSMUSG00000041258
AA Change: Q837K
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
39 |
61 |
2.24e-3 |
SMART |
|
ZnF_C2H2
|
68 |
90 |
2.29e0 |
SMART |
|
ZnF_C2H2
|
95 |
117 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
123 |
145 |
6.67e-2 |
SMART |
|
ZnF_C2H2
|
155 |
177 |
6.42e-4 |
SMART |
|
ZnF_C2H2
|
199 |
221 |
1.75e-5 |
SMART |
|
ZnF_C2H2
|
227 |
249 |
1.52e-5 |
SMART |
|
ZnF_C2H2
|
255 |
278 |
8.94e-3 |
SMART |
|
low complexity region
|
290 |
309 |
N/A |
INTRINSIC |
|
low complexity region
|
403 |
426 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
436 |
458 |
1.98e-4 |
SMART |
|
ZnF_C2H2
|
464 |
486 |
9.58e-3 |
SMART |
|
ZnF_C2H2
|
492 |
514 |
6.42e-4 |
SMART |
|
ZnF_C2H2
|
520 |
542 |
1.18e-2 |
SMART |
|
low complexity region
|
592 |
605 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
611 |
633 |
1.62e0 |
SMART |
|
ZnF_C2H2
|
639 |
661 |
5.21e-4 |
SMART |
|
ZnF_C2H2
|
667 |
689 |
6.78e-3 |
SMART |
|
ZnF_C2H2
|
695 |
717 |
7.37e-4 |
SMART |
|
low complexity region
|
720 |
733 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
922 |
944 |
5.21e-4 |
SMART |
|
ZnF_C2H2
|
950 |
972 |
1.04e-3 |
SMART |
|
ZnF_C2H2
|
978 |
1000 |
8.6e-5 |
SMART |
|
ZnF_C2H2
|
1006 |
1028 |
2.75e-3 |
SMART |
|
low complexity region
|
1030 |
1039 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1122 |
1144 |
7.78e-3 |
SMART |
|
ZnF_C2H2
|
1150 |
1172 |
3.63e-3 |
SMART |
|
ZnF_C2H2
|
1178 |
1200 |
6.88e-4 |
SMART |
|
ZnF_C2H2
|
1206 |
1228 |
5.42e-2 |
SMART |
|
low complexity region
|
1243 |
1258 |
N/A |
INTRINSIC |
|
low complexity region
|
1462 |
1477 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1612 |
1635 |
7.15e-2 |
SMART |
|
ZnF_C2H2
|
1641 |
1663 |
2.91e-2 |
SMART |
|
ZnF_C2H2
|
1677 |
1699 |
7.26e-3 |
SMART |
|
ZnF_C2H2
|
1705 |
1727 |
1.84e-4 |
SMART |
|
ZnF_C2H2
|
1733 |
1756 |
2.95e-3 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000182122
AA Change: Q885K
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000138557
Gene: ENSMUSG00000041258
AA Change: Q885K
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
39 |
61 |
2.24e-3 |
SMART |
|
ZnF_C2H2
|
68 |
90 |
2.29e0 |
SMART |
|
ZnF_C2H2
|
95 |
117 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
123 |
145 |
6.67e-2 |
SMART |
|
ZnF_C2H2
|
155 |
177 |
6.42e-4 |
SMART |
|
ZnF_C2H2
|
199 |
221 |
1.75e-5 |
SMART |
|
ZnF_C2H2
|
227 |
249 |
1.52e-5 |
SMART |
|
ZnF_C2H2
|
255 |
278 |
8.94e-3 |
SMART |
|
ZnF_C2H2
|
287 |
310 |
9.58e-3 |
SMART |
|
low complexity region
|
338 |
357 |
N/A |
INTRINSIC |
|
low complexity region
|
451 |
474 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
484 |
506 |
1.98e-4 |
SMART |
|
ZnF_C2H2
|
512 |
534 |
9.58e-3 |
SMART |
|
ZnF_C2H2
|
540 |
562 |
6.42e-4 |
SMART |
|
ZnF_C2H2
|
568 |
590 |
1.18e-2 |
SMART |
|
low complexity region
|
640 |
653 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
659 |
681 |
1.62e0 |
SMART |
|
ZnF_C2H2
|
687 |
709 |
5.21e-4 |
SMART |
|
ZnF_C2H2
|
715 |
737 |
6.78e-3 |
SMART |
|
ZnF_C2H2
|
743 |
765 |
7.37e-4 |
SMART |
|
low complexity region
|
768 |
781 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
970 |
992 |
5.21e-4 |
SMART |
|
ZnF_C2H2
|
998 |
1020 |
1.04e-3 |
SMART |
|
ZnF_C2H2
|
1026 |
1048 |
8.6e-5 |
SMART |
|
ZnF_C2H2
|
1054 |
1076 |
2.75e-3 |
SMART |
|
low complexity region
|
1078 |
1087 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1170 |
1192 |
7.78e-3 |
SMART |
|
ZnF_C2H2
|
1198 |
1220 |
3.63e-3 |
SMART |
|
ZnF_C2H2
|
1226 |
1248 |
6.88e-4 |
SMART |
|
ZnF_C2H2
|
1254 |
1276 |
5.42e-2 |
SMART |
|
low complexity region
|
1291 |
1306 |
N/A |
INTRINSIC |
|
low complexity region
|
1510 |
1525 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1660 |
1683 |
7.15e-2 |
SMART |
|
ZnF_C2H2
|
1689 |
1711 |
2.91e-2 |
SMART |
|
ZnF_C2H2
|
1725 |
1747 |
7.26e-3 |
SMART |
|
ZnF_C2H2
|
1753 |
1775 |
1.84e-4 |
SMART |
|
ZnF_C2H2
|
1781 |
1804 |
2.95e-3 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000183048
|
| SMART Domains |
Protein: ENSMUSP00000138179
Gene: ENSMUSG00000041258
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
39 |
61 |
2.24e-3 |
SMART |
|
ZnF_C2H2
|
68 |
90 |
2.29e0 |
SMART |
|
ZnF_C2H2
|
95 |
117 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
123 |
145 |
6.67e-2 |
SMART |
|
ZnF_C2H2
|
155 |
177 |
6.42e-4 |
SMART |
|
ZnF_C2H2
|
199 |
221 |
1.75e-5 |
SMART |
|
ZnF_C2H2
|
227 |
249 |
1.52e-5 |
SMART |
|
ZnF_C2H2
|
255 |
278 |
8.94e-3 |
SMART |
|
ZnF_C2H2
|
287 |
310 |
9.58e-3 |
SMART |
|
low complexity region
|
338 |
357 |
N/A |
INTRINSIC |
|
low complexity region
|
454 |
467 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.4%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 88 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adck5 |
A |
T |
15: 76,479,396 (GRCm39) |
I484F |
possibly damaging |
Het |
| Ago2 |
A |
T |
15: 73,009,881 (GRCm39) |
N100K |
probably benign |
Het |
| Appl1 |
T |
A |
14: 26,681,409 (GRCm39) |
K130* |
probably null |
Het |
| Arhgap39 |
G |
A |
15: 76,649,797 (GRCm39) |
|
probably benign |
Het |
| Axdnd1 |
A |
G |
1: 156,245,802 (GRCm39) |
|
probably null |
Het |
| Camta1 |
A |
T |
4: 151,168,327 (GRCm39) |
V1332E |
probably benign |
Het |
| Cd3g |
A |
G |
9: 44,884,857 (GRCm39) |
L129P |
probably damaging |
Het |
| Cd80 |
T |
G |
16: 38,294,251 (GRCm39) |
S45A |
probably benign |
Het |
| Cdk12 |
A |
T |
11: 98,136,106 (GRCm39) |
Q1120L |
unknown |
Het |
| Clip1 |
G |
A |
5: 123,791,696 (GRCm39) |
S158F |
probably benign |
Het |
| Cntn3 |
C |
A |
6: 102,255,416 (GRCm39) |
E161* |
probably null |
Het |
| Cyp3a59 |
A |
C |
5: 146,024,215 (GRCm39) |
K67T |
probably benign |
Het |
| Dmxl1 |
T |
C |
18: 49,997,681 (GRCm39) |
L623P |
probably damaging |
Het |
| Drd3 |
T |
A |
16: 43,637,426 (GRCm39) |
Y208* |
probably null |
Het |
| Dusp10 |
A |
T |
1: 183,801,153 (GRCm39) |
M307L |
probably benign |
Het |
| Dync2li1 |
A |
T |
17: 84,955,141 (GRCm39) |
I267L |
possibly damaging |
Het |
| Dynlt2b |
T |
A |
16: 32,244,089 (GRCm39) |
V95E |
probably damaging |
Het |
| Edn3 |
C |
A |
2: 174,603,544 (GRCm39) |
C97* |
probably null |
Het |
| Ehbp1l1 |
T |
A |
19: 5,769,456 (GRCm39) |
T616S |
possibly damaging |
Het |
| Eif2a |
C |
T |
3: 58,452,963 (GRCm39) |
T246I |
probably damaging |
Het |
| Enpp5 |
G |
A |
17: 44,396,155 (GRCm39) |
G356S |
probably damaging |
Het |
| Errfi1 |
A |
G |
4: 150,951,108 (GRCm39) |
T179A |
probably damaging |
Het |
| Esyt3 |
G |
A |
9: 99,203,615 (GRCm39) |
L450F |
probably damaging |
Het |
| Evx2 |
A |
G |
2: 74,489,448 (GRCm39) |
S106P |
probably benign |
Het |
| Fam83a |
T |
G |
15: 57,873,086 (GRCm39) |
V305G |
probably benign |
Het |
| Fem1al |
T |
C |
11: 29,774,122 (GRCm39) |
D445G |
probably benign |
Het |
| Gpr171 |
T |
A |
3: 59,005,860 (GRCm39) |
|
probably null |
Het |
| Grip1 |
A |
G |
10: 119,922,871 (GRCm39) |
T1106A |
probably benign |
Het |
| Hecw1 |
A |
G |
13: 14,531,789 (GRCm39) |
Y162H |
probably damaging |
Het |
| Hephl1 |
C |
T |
9: 15,009,178 (GRCm39) |
|
probably null |
Het |
| Hsp90aa1 |
A |
G |
12: 110,658,562 (GRCm39) |
I693T |
possibly damaging |
Het |
| Ifit1bl2 |
T |
A |
19: 34,596,974 (GRCm39) |
D214V |
probably damaging |
Het |
| Igsf10 |
T |
C |
3: 59,239,222 (GRCm39) |
M320V |
probably benign |
Het |
| Kcnq2 |
A |
G |
2: 180,754,887 (GRCm39) |
L220P |
probably damaging |
Het |
| Kpna1 |
C |
A |
16: 35,850,009 (GRCm39) |
Q372K |
probably damaging |
Het |
| Lilrb4a |
T |
G |
10: 51,367,149 (GRCm39) |
|
probably null |
Het |
| Ly75 |
C |
A |
2: 60,164,818 (GRCm39) |
E787* |
probably null |
Het |
| Magi1 |
T |
G |
6: 93,722,562 (GRCm39) |
S666R |
possibly damaging |
Het |
| Mif |
C |
A |
10: 75,695,687 (GRCm39) |
A39S |
possibly damaging |
Het |
| Mob4 |
G |
A |
1: 55,170,625 (GRCm39) |
|
probably benign |
Het |
| Mtmr4 |
G |
T |
11: 87,502,727 (GRCm39) |
C927F |
probably damaging |
Het |
| Myh1 |
A |
G |
11: 67,110,006 (GRCm39) |
K1398R |
probably benign |
Het |
| Myo3a |
T |
C |
2: 22,436,464 (GRCm39) |
V873A |
probably benign |
Het |
| Naip5 |
G |
T |
13: 100,356,205 (GRCm39) |
Q1137K |
not run |
Het |
| Naip5 |
T |
C |
13: 100,356,204 (GRCm39) |
Q1137R |
probably benign |
Het |
| Nckap5l |
G |
A |
15: 99,325,357 (GRCm39) |
P382L |
probably damaging |
Het |
| Ngly1 |
T |
C |
14: 16,290,844 (GRCm38) |
I442T |
probably damaging |
Het |
| Nhsl3 |
C |
A |
4: 129,115,835 (GRCm39) |
R988L |
possibly damaging |
Het |
| Nlrp1a |
T |
C |
11: 70,983,237 (GRCm39) |
Y1243C |
probably damaging |
Het |
| Or8k53 |
T |
A |
2: 86,177,150 (GRCm39) |
H320L |
possibly damaging |
Het |
| Pcsk5 |
C |
T |
19: 17,487,600 (GRCm39) |
G1027D |
probably benign |
Het |
| Pla2g2c |
T |
A |
4: 138,458,927 (GRCm39) |
I11N |
probably benign |
Het |
| Polr3d |
A |
G |
14: 70,677,240 (GRCm39) |
I331T |
probably damaging |
Het |
| Ppp4r4 |
A |
G |
12: 103,551,985 (GRCm39) |
I293M |
possibly damaging |
Het |
| Prkce |
G |
T |
17: 86,866,687 (GRCm39) |
V516F |
probably damaging |
Het |
| Prss27 |
T |
A |
17: 24,264,683 (GRCm39) |
L282Q |
probably damaging |
Het |
| Pxdn |
A |
G |
12: 30,034,926 (GRCm39) |
Y261C |
probably damaging |
Het |
| R3hcc1l |
T |
C |
19: 42,551,101 (GRCm39) |
S33P |
probably benign |
Het |
| Rab11fip3 |
G |
C |
17: 26,287,848 (GRCm39) |
R102G |
possibly damaging |
Het |
| Rabggta |
A |
T |
14: 55,956,773 (GRCm39) |
N310K |
probably null |
Het |
| Rbbp8 |
T |
A |
18: 11,793,934 (GRCm39) |
D15E |
probably benign |
Het |
| Rbm5 |
T |
C |
9: 107,623,378 (GRCm39) |
Y486C |
probably damaging |
Het |
| Rptor |
T |
A |
11: 119,775,805 (GRCm39) |
F992Y |
probably benign |
Het |
| Slc29a2 |
T |
G |
19: 5,076,445 (GRCm39) |
L111R |
probably damaging |
Het |
| Slc39a11 |
T |
A |
11: 113,452,849 (GRCm39) |
I31L |
probably benign |
Het |
| Slc6a20a |
T |
A |
9: 123,485,289 (GRCm39) |
N311I |
possibly damaging |
Het |
| Slc8a1 |
A |
G |
17: 81,956,435 (GRCm39) |
F201S |
probably damaging |
Het |
| Smtn |
C |
A |
11: 3,480,196 (GRCm39) |
V342L |
probably benign |
Het |
| Syne2 |
A |
G |
12: 76,074,853 (GRCm39) |
T4598A |
probably benign |
Het |
| Tchp |
A |
G |
5: 114,853,716 (GRCm39) |
T267A |
probably benign |
Het |
| Tes3-ps |
A |
G |
13: 49,647,508 (GRCm39) |
E128G |
possibly damaging |
Het |
| Tigar |
C |
T |
6: 127,065,129 (GRCm39) |
G173E |
probably benign |
Het |
| Tmem171 |
T |
C |
13: 98,824,862 (GRCm39) |
N256S |
probably benign |
Het |
| Tmem204 |
A |
G |
17: 25,277,270 (GRCm39) |
I205T |
probably damaging |
Het |
| Tmem63a |
A |
G |
1: 180,785,588 (GRCm39) |
K240R |
probably benign |
Het |
| Tns2 |
C |
T |
15: 102,019,351 (GRCm39) |
T446M |
probably damaging |
Het |
| Tnxb |
A |
T |
17: 34,937,444 (GRCm39) |
N2931I |
probably damaging |
Het |
| Trrap |
G |
T |
5: 144,776,284 (GRCm39) |
R2941L |
probably damaging |
Het |
| Ttc8 |
A |
T |
12: 98,910,131 (GRCm39) |
R179S |
probably damaging |
Het |
| Ttll12 |
G |
T |
15: 83,471,176 (GRCm39) |
T234N |
probably damaging |
Het |
| Ttn |
G |
T |
2: 76,577,576 (GRCm39) |
T24439K |
probably damaging |
Het |
| Ube2z |
A |
T |
11: 95,946,736 (GRCm39) |
I246N |
possibly damaging |
Het |
| Usp15 |
A |
G |
10: 123,011,786 (GRCm39) |
Y104H |
probably damaging |
Het |
| Usp29 |
A |
C |
7: 6,964,219 (GRCm39) |
T21P |
possibly damaging |
Het |
| Usp5 |
G |
A |
6: 124,798,077 (GRCm39) |
A436V |
probably damaging |
Het |
| Utp20 |
A |
G |
10: 88,608,354 (GRCm39) |
L1561S |
probably damaging |
Het |
| Xrn1 |
A |
G |
9: 95,927,547 (GRCm39) |
M1444V |
probably benign |
Het |
| Zfp831 |
C |
A |
2: 174,487,896 (GRCm39) |
P857Q |
possibly damaging |
Het |
|
| Other mutations in Zfp236 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01016:Zfp236
|
APN |
18 |
82,686,815 (GRCm39) |
missense |
probably benign |
0.44 |
|
IGL01760:Zfp236
|
APN |
18 |
82,639,547 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01923:Zfp236
|
APN |
18 |
82,700,344 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01934:Zfp236
|
APN |
18 |
82,651,245 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01949:Zfp236
|
APN |
18 |
82,642,521 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02063:Zfp236
|
APN |
18 |
82,676,276 (GRCm39) |
missense |
probably benign |
|
|
IGL02496:Zfp236
|
APN |
18 |
82,648,117 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02513:Zfp236
|
APN |
18 |
82,648,239 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02626:Zfp236
|
APN |
18 |
82,676,120 (GRCm39) |
splice site |
probably benign |
|
|
IGL02880:Zfp236
|
APN |
18 |
82,642,584 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL03156:Zfp236
|
APN |
18 |
82,698,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03261:Zfp236
|
APN |
18 |
82,648,733 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0047:Zfp236
|
UTSW |
18 |
82,698,817 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0052:Zfp236
|
UTSW |
18 |
82,657,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0194:Zfp236
|
UTSW |
18 |
82,675,112 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0207:Zfp236
|
UTSW |
18 |
82,658,352 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0234:Zfp236
|
UTSW |
18 |
82,648,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0234:Zfp236
|
UTSW |
18 |
82,648,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0302:Zfp236
|
UTSW |
18 |
82,676,213 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0730:Zfp236
|
UTSW |
18 |
82,658,369 (GRCm39) |
splice site |
probably benign |
|
|
R0755:Zfp236
|
UTSW |
18 |
82,638,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1202:Zfp236
|
UTSW |
18 |
82,646,291 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1449:Zfp236
|
UTSW |
18 |
82,664,130 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1550:Zfp236
|
UTSW |
18 |
82,692,549 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R1785:Zfp236
|
UTSW |
18 |
82,639,429 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1786:Zfp236
|
UTSW |
18 |
82,639,429 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2042:Zfp236
|
UTSW |
18 |
82,651,234 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2132:Zfp236
|
UTSW |
18 |
82,639,429 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2133:Zfp236
|
UTSW |
18 |
82,639,429 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2247:Zfp236
|
UTSW |
18 |
82,622,423 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R2484:Zfp236
|
UTSW |
18 |
82,686,762 (GRCm39) |
missense |
probably benign |
0.05 |
|
R3715:Zfp236
|
UTSW |
18 |
82,651,095 (GRCm39) |
splice site |
probably benign |
|
|
R4003:Zfp236
|
UTSW |
18 |
82,698,870 (GRCm39) |
nonsense |
probably null |
|
|
R4031:Zfp236
|
UTSW |
18 |
82,642,590 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4482:Zfp236
|
UTSW |
18 |
82,662,346 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4492:Zfp236
|
UTSW |
18 |
82,648,125 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4502:Zfp236
|
UTSW |
18 |
82,655,079 (GRCm39) |
missense |
probably benign |
0.13 |
|
R4561:Zfp236
|
UTSW |
18 |
82,638,531 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4649:Zfp236
|
UTSW |
18 |
82,615,784 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4902:Zfp236
|
UTSW |
18 |
82,627,543 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5064:Zfp236
|
UTSW |
18 |
82,709,701 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5084:Zfp236
|
UTSW |
18 |
82,627,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5090:Zfp236
|
UTSW |
18 |
82,637,006 (GRCm39) |
missense |
probably benign |
0.08 |
|
R5191:Zfp236
|
UTSW |
18 |
82,639,548 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5264:Zfp236
|
UTSW |
18 |
82,676,198 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5264:Zfp236
|
UTSW |
18 |
82,648,219 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5339:Zfp236
|
UTSW |
18 |
82,642,491 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5375:Zfp236
|
UTSW |
18 |
82,615,813 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5445:Zfp236
|
UTSW |
18 |
82,700,281 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5513:Zfp236
|
UTSW |
18 |
82,676,147 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5527:Zfp236
|
UTSW |
18 |
82,676,159 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R5628:Zfp236
|
UTSW |
18 |
82,675,247 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5758:Zfp236
|
UTSW |
18 |
82,689,834 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5890:Zfp236
|
UTSW |
18 |
82,658,276 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R6137:Zfp236
|
UTSW |
18 |
82,689,919 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6193:Zfp236
|
UTSW |
18 |
82,622,372 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6198:Zfp236
|
UTSW |
18 |
82,675,278 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6239:Zfp236
|
UTSW |
18 |
82,675,229 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R6705:Zfp236
|
UTSW |
18 |
82,651,862 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6948:Zfp236
|
UTSW |
18 |
82,662,187 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6989:Zfp236
|
UTSW |
18 |
82,646,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7002:Zfp236
|
UTSW |
18 |
82,709,701 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7113:Zfp236
|
UTSW |
18 |
82,638,462 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R7261:Zfp236
|
UTSW |
18 |
82,627,470 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R7363:Zfp236
|
UTSW |
18 |
82,639,456 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7564:Zfp236
|
UTSW |
18 |
82,662,366 (GRCm39) |
nonsense |
probably null |
|
|
R7731:Zfp236
|
UTSW |
18 |
82,698,798 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7857:Zfp236
|
UTSW |
18 |
82,686,726 (GRCm39) |
nonsense |
probably null |
|
|
R7860:Zfp236
|
UTSW |
18 |
82,692,481 (GRCm39) |
nonsense |
probably null |
|
|
R7904:Zfp236
|
UTSW |
18 |
82,627,507 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7948:Zfp236
|
UTSW |
18 |
82,642,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7995:Zfp236
|
UTSW |
18 |
82,657,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8153:Zfp236
|
UTSW |
18 |
82,648,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8435:Zfp236
|
UTSW |
18 |
82,658,366 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8560:Zfp236
|
UTSW |
18 |
82,664,340 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8878:Zfp236
|
UTSW |
18 |
82,617,122 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8916:Zfp236
|
UTSW |
18 |
82,664,351 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9046:Zfp236
|
UTSW |
18 |
82,637,042 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9076:Zfp236
|
UTSW |
18 |
82,638,469 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R9243:Zfp236
|
UTSW |
18 |
82,662,050 (GRCm39) |
intron |
probably benign |
|
|
R9594:Zfp236
|
UTSW |
18 |
82,664,238 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9642:Zfp236
|
UTSW |
18 |
82,622,384 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9707:Zfp236
|
UTSW |
18 |
82,664,328 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9748:Zfp236
|
UTSW |
18 |
82,637,008 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
| Predicted Primers |
PCR Primer
(F):5'- CTGCTTTCTCTAGGACAGGGAC -3'
(R):5'- GCAGCATACTTCTGGATGGGTC -3'
Sequencing Primer
(F):5'- CCTGGATAGAACAGCTACGAATTTC -3'
(R):5'- CATACTTCTGGATGGGTCGGCAG -3'
|
| Posted On |
2019-10-07 |
Incidental Mutation