Incidental Mutation 'R7454:Ralgapb'
| ID |
577966 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ralgapb
|
| Ensembl Gene |
ENSMUSG00000027652 |
| Gene Name |
Ral GTPase activating protein, beta subunit (non-catalytic) |
| Synonyms |
B230339M05Rik |
| MMRRC Submission |
045528-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R7454 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
158251768-158341173 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 158274822 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Asparagine
at position 241
(I241N)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000105111
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000046274]
[ENSMUST00000109485]
[ENSMUST00000109486]
[ENSMUST00000141497]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000046274
AA Change: I241N
PolyPhen 2
Score 0.937 (Sensitivity: 0.80; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000048430
Gene: ENSMUSG00000027652
AA Change: I241N
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
166 |
178 |
N/A |
INTRINSIC |
|
low complexity region
|
610 |
625 |
N/A |
INTRINSIC |
|
low complexity region
|
775 |
788 |
N/A |
INTRINSIC |
|
low complexity region
|
910 |
920 |
N/A |
INTRINSIC |
|
low complexity region
|
1086 |
1097 |
N/A |
INTRINSIC |
|
low complexity region
|
1309 |
1321 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000109485
AA Change: I241N
PolyPhen 2
Score 0.937 (Sensitivity: 0.80; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000105111
Gene: ENSMUSG00000027652
AA Change: I241N
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
166 |
178 |
N/A |
INTRINSIC |
|
low complexity region
|
622 |
637 |
N/A |
INTRINSIC |
|
low complexity region
|
791 |
804 |
N/A |
INTRINSIC |
|
low complexity region
|
926 |
936 |
N/A |
INTRINSIC |
|
low complexity region
|
1102 |
1113 |
N/A |
INTRINSIC |
|
low complexity region
|
1325 |
1337 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000109486
AA Change: I241N
PolyPhen 2
Score 0.937 (Sensitivity: 0.80; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000105112
Gene: ENSMUSG00000027652
AA Change: I241N
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
166 |
178 |
N/A |
INTRINSIC |
|
low complexity region
|
610 |
625 |
N/A |
INTRINSIC |
|
low complexity region
|
779 |
792 |
N/A |
INTRINSIC |
|
low complexity region
|
914 |
924 |
N/A |
INTRINSIC |
|
low complexity region
|
1090 |
1101 |
N/A |
INTRINSIC |
|
low complexity region
|
1313 |
1325 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000141497
|
| SMART Domains |
Protein: ENSMUSP00000116481
Gene: ENSMUSG00000027652
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
288 |
303 |
N/A |
INTRINSIC |
|
low complexity region
|
457 |
470 |
N/A |
INTRINSIC |
|
low complexity region
|
592 |
602 |
N/A |
INTRINSIC |
|
low complexity region
|
768 |
779 |
N/A |
INTRINSIC |
|
low complexity region
|
991 |
1003 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
100% (90/90) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 89 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2510002D24Rik |
A |
G |
16: 18,655,601 (GRCm39) |
E57G |
possibly damaging |
Het |
| 4932414N04Rik |
C |
A |
2: 68,518,648 (GRCm39) |
T159K |
unknown |
Het |
| Adamts10 |
T |
A |
17: 33,763,979 (GRCm39) |
F616L |
possibly damaging |
Het |
| Adtrp |
G |
A |
13: 41,981,791 (GRCm39) |
S26L |
unknown |
Het |
| Alpk3 |
A |
C |
7: 80,728,310 (GRCm39) |
E480A |
probably benign |
Het |
| Anks6 |
T |
C |
4: 47,038,919 (GRCm39) |
T529A |
unknown |
Het |
| Arl4d |
A |
G |
11: 101,557,486 (GRCm39) |
H4R |
probably benign |
Het |
| Ash1l |
A |
G |
3: 88,891,172 (GRCm39) |
H1017R |
probably benign |
Het |
| Bbs12 |
T |
C |
3: 37,375,102 (GRCm39) |
S517P |
possibly damaging |
Het |
| Bcl11b |
C |
A |
12: 107,882,467 (GRCm39) |
R616L |
possibly damaging |
Het |
| Bean1 |
G |
A |
8: 104,937,658 (GRCm39) |
G79D |
probably damaging |
Het |
| Bicra |
C |
G |
7: 15,706,059 (GRCm39) |
G1461R |
probably benign |
Het |
| Bptf |
T |
C |
11: 106,935,466 (GRCm39) |
T124A |
probably benign |
Het |
| Btnl4 |
A |
T |
17: 34,691,348 (GRCm39) |
V312E |
probably benign |
Het |
| Ccdc7a |
A |
G |
8: 129,670,997 (GRCm39) |
M503T |
unknown |
Het |
| Celf5 |
T |
C |
10: 81,318,357 (GRCm39) |
E28G |
probably damaging |
Het |
| Cilp2 |
G |
A |
8: 70,336,040 (GRCm39) |
L350F |
probably damaging |
Het |
| Clec4a2 |
T |
C |
6: 123,119,411 (GRCm39) |
I245T |
probably damaging |
Het |
| Ctnnal1 |
A |
T |
4: 56,844,544 (GRCm39) |
V140D |
probably damaging |
Het |
| Dennd4a |
A |
C |
9: 64,759,852 (GRCm39) |
H319P |
probably damaging |
Het |
| Dlgap3 |
G |
T |
4: 127,128,852 (GRCm39) |
L857F |
probably null |
Het |
| Dnah6 |
T |
A |
6: 73,189,475 (GRCm39) |
T58S |
probably damaging |
Het |
| Dnah7a |
T |
A |
1: 53,557,923 (GRCm39) |
M2164L |
probably benign |
Het |
| Dspp |
T |
A |
5: 104,323,476 (GRCm39) |
H206Q |
probably benign |
Het |
| Dzip1l |
G |
A |
9: 99,541,727 (GRCm39) |
V443M |
possibly damaging |
Het |
| Erc2 |
A |
G |
14: 28,024,948 (GRCm39) |
H939R |
possibly damaging |
Het |
| Fam149a |
G |
T |
8: 45,801,583 (GRCm39) |
H513N |
probably benign |
Het |
| Fam171a2 |
T |
C |
11: 102,330,543 (GRCm39) |
T280A |
possibly damaging |
Het |
| Fkbp5 |
A |
C |
17: 28,634,999 (GRCm39) |
V170G |
probably damaging |
Het |
| Fnbp4 |
ACCACCTCCACCTCCACCTCC |
ACCACCTCCACCTCCACCTCCACCTCC |
2: 90,608,159 (GRCm39) |
|
probably benign |
Het |
| Fzd2 |
T |
C |
11: 102,495,955 (GRCm39) |
F133S |
probably damaging |
Het |
| Galm |
A |
G |
17: 80,445,550 (GRCm39) |
N100S |
possibly damaging |
Het |
| Gbp2b |
T |
A |
3: 142,303,920 (GRCm39) |
I5N |
possibly damaging |
Het |
| Gga2 |
T |
C |
7: 121,601,369 (GRCm39) |
R245G |
probably benign |
Het |
| Gm10053 |
A |
G |
19: 24,853,264 (GRCm39) |
T50A |
probably benign |
Het |
| Gm1110 |
T |
C |
9: 26,831,945 (GRCm39) |
T69A |
probably benign |
Het |
| Heatr5a |
T |
C |
12: 52,008,326 (GRCm39) |
S6G |
probably benign |
Het |
| Hmcn1 |
A |
G |
1: 150,439,355 (GRCm39) |
S5610P |
probably damaging |
Het |
| Hmgb4 |
A |
G |
4: 128,154,199 (GRCm39) |
V123A |
probably damaging |
Het |
| Itgal |
C |
A |
7: 126,926,936 (GRCm39) |
Q943K |
probably benign |
Het |
| Jakmip1 |
C |
A |
5: 37,332,498 (GRCm39) |
D1059E |
probably damaging |
Het |
| Jazf1 |
T |
C |
6: 52,870,929 (GRCm39) |
|
probably null |
Het |
| Kat6a |
A |
G |
8: 23,425,788 (GRCm39) |
E1111G |
possibly damaging |
Het |
| Kdm4b |
C |
A |
17: 56,696,639 (GRCm39) |
P452T |
probably benign |
Het |
| Krit1 |
T |
C |
5: 3,862,474 (GRCm39) |
Y210H |
probably damaging |
Het |
| Krtap6-2 |
A |
T |
16: 89,216,800 (GRCm39) |
Y56N |
unknown |
Het |
| Lig1 |
A |
T |
7: 13,022,647 (GRCm39) |
D158V |
probably damaging |
Het |
| Lmo1 |
A |
T |
7: 108,739,873 (GRCm39) |
L94Q |
probably benign |
Het |
| Lrrc30 |
A |
T |
17: 67,939,238 (GRCm39) |
L114H |
probably damaging |
Het |
| Ltn1 |
T |
C |
16: 87,194,700 (GRCm39) |
I1400V |
probably benign |
Het |
| Mark3 |
T |
C |
12: 111,570,961 (GRCm39) |
I87T |
probably damaging |
Het |
| Mfrp |
G |
T |
9: 44,016,480 (GRCm39) |
V392F |
possibly damaging |
Het |
| Mrgprg |
A |
G |
7: 143,318,872 (GRCm39) |
L80P |
probably damaging |
Het |
| Ndufaf3 |
A |
T |
9: 108,444,125 (GRCm39) |
M1K |
probably null |
Het |
| Nme7 |
T |
A |
1: 164,208,217 (GRCm39) |
L295* |
probably null |
Het |
| Noct |
G |
T |
3: 51,157,151 (GRCm39) |
C163F |
probably damaging |
Het |
| Or11h4b |
T |
A |
14: 50,918,281 (GRCm39) |
Q270L |
possibly damaging |
Het |
| Or13a26 |
A |
T |
7: 140,284,547 (GRCm39) |
I128F |
probably damaging |
Het |
| Or4b1 |
T |
A |
2: 89,979,763 (GRCm39) |
I196F |
possibly damaging |
Het |
| Or5ak22 |
T |
A |
2: 85,229,955 (GRCm39) |
K307N |
probably damaging |
Het |
| Or6c203 |
T |
A |
10: 129,010,324 (GRCm39) |
T189S |
probably damaging |
Het |
| Or8g2 |
A |
G |
9: 39,821,200 (GRCm39) |
I34V |
probably benign |
Het |
| Patz1 |
C |
T |
11: 3,248,297 (GRCm39) |
|
probably benign |
Het |
| Per3 |
A |
G |
4: 151,097,185 (GRCm39) |
L780P |
probably benign |
Het |
| Pira1 |
T |
G |
7: 3,738,509 (GRCm39) |
E622D |
probably benign |
Het |
| Pla2g4a |
T |
C |
1: 149,748,441 (GRCm39) |
M256V |
possibly damaging |
Het |
| Pnliprp1 |
A |
G |
19: 58,729,532 (GRCm39) |
K395R |
probably benign |
Het |
| Poc5 |
G |
T |
13: 96,537,340 (GRCm39) |
G242V |
possibly damaging |
Het |
| Ppfia4 |
A |
G |
1: 134,251,873 (GRCm39) |
S434P |
possibly damaging |
Het |
| Prss42 |
A |
G |
9: 110,627,897 (GRCm39) |
N110S |
probably benign |
Het |
| Rbak |
A |
C |
5: 143,159,528 (GRCm39) |
Y508* |
probably null |
Het |
| S1pr2 |
G |
T |
9: 20,878,845 (GRCm39) |
R328S |
possibly damaging |
Het |
| Sap130 |
T |
C |
18: 31,783,565 (GRCm39) |
M214T |
probably benign |
Het |
| Slc46a1 |
T |
A |
11: 78,357,337 (GRCm39) |
V130E |
probably damaging |
Het |
| Smc4 |
A |
T |
3: 68,925,457 (GRCm39) |
H343L |
probably benign |
Het |
| Tarbp1 |
C |
A |
8: 127,184,416 (GRCm39) |
R500L |
probably benign |
Het |
| Tasor2 |
A |
G |
13: 3,635,332 (GRCm39) |
S492P |
probably benign |
Het |
| Tgfbr3 |
A |
T |
5: 107,362,894 (GRCm39) |
H39Q |
probably damaging |
Het |
| Tpp2 |
T |
C |
1: 43,993,819 (GRCm39) |
S235P |
probably benign |
Het |
| Trbc2 |
G |
T |
6: 41,523,763 (GRCm39) |
R33M |
|
Het |
| Trim3 |
C |
T |
7: 105,268,765 (GRCm39) |
R63Q |
probably damaging |
Het |
| Ttc28 |
T |
C |
5: 111,433,350 (GRCm39) |
V2128A |
probably benign |
Het |
| Ttn |
C |
T |
2: 76,556,162 (GRCm39) |
R30281H |
probably damaging |
Het |
| Ttn |
T |
A |
2: 76,774,483 (GRCm39) |
Q2187L |
unknown |
Het |
| Ttyh3 |
T |
C |
5: 140,615,180 (GRCm39) |
S403G |
possibly damaging |
Het |
| Vmn2r112 |
A |
T |
17: 22,822,288 (GRCm39) |
D322V |
probably benign |
Het |
| Wdr38 |
C |
T |
2: 38,888,352 (GRCm39) |
|
probably benign |
Het |
| Xrn1 |
T |
A |
9: 95,930,411 (GRCm39) |
S1543R |
probably benign |
Het |
| Zbtb8b |
G |
A |
4: 129,326,562 (GRCm39) |
T201I |
possibly damaging |
Het |
|
| Other mutations in Ralgapb |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00094:Ralgapb
|
APN |
2 |
158,262,776 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00534:Ralgapb
|
APN |
2 |
158,272,420 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
IGL01362:Ralgapb
|
APN |
2 |
158,277,385 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01653:Ralgapb
|
APN |
2 |
158,304,079 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01704:Ralgapb
|
APN |
2 |
158,262,795 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02000:Ralgapb
|
APN |
2 |
158,296,034 (GRCm39) |
splice site |
probably benign |
|
|
IGL02169:Ralgapb
|
APN |
2 |
158,268,124 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02516:Ralgapb
|
APN |
2 |
158,307,735 (GRCm39) |
splice site |
probably benign |
|
|
IGL02548:Ralgapb
|
APN |
2 |
158,286,585 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02550:Ralgapb
|
APN |
2 |
158,290,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02653:Ralgapb
|
APN |
2 |
158,285,229 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02744:Ralgapb
|
APN |
2 |
158,288,071 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02804:Ralgapb
|
APN |
2 |
158,268,204 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
IGL02937:Ralgapb
|
APN |
2 |
158,334,936 (GRCm39) |
splice site |
probably null |
|
|
IGL02993:Ralgapb
|
APN |
2 |
158,279,314 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL03154:Ralgapb
|
APN |
2 |
158,274,786 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03204:Ralgapb
|
APN |
2 |
158,307,832 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
IGL03347:Ralgapb
|
APN |
2 |
158,307,880 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
Chacha
|
UTSW |
2 |
158,334,372 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Gato
|
UTSW |
2 |
158,286,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Kibble
|
UTSW |
2 |
158,279,060 (GRCm39) |
missense |
probably damaging |
1.00 |
|
ralston
|
UTSW |
2 |
158,296,197 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4142001:Ralgapb
|
UTSW |
2 |
158,272,342 (GRCm39) |
missense |
probably benign |
0.34 |
|
R0037:Ralgapb
|
UTSW |
2 |
158,279,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0037:Ralgapb
|
UTSW |
2 |
158,279,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0077:Ralgapb
|
UTSW |
2 |
158,315,169 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0581:Ralgapb
|
UTSW |
2 |
158,334,881 (GRCm39) |
missense |
probably benign |
|
|
R0629:Ralgapb
|
UTSW |
2 |
158,281,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0839:Ralgapb
|
UTSW |
2 |
158,315,203 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1331:Ralgapb
|
UTSW |
2 |
158,272,453 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1468:Ralgapb
|
UTSW |
2 |
158,304,173 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1468:Ralgapb
|
UTSW |
2 |
158,304,173 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1540:Ralgapb
|
UTSW |
2 |
158,307,746 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1572:Ralgapb
|
UTSW |
2 |
158,288,119 (GRCm39) |
splice site |
probably benign |
|
|
R1628:Ralgapb
|
UTSW |
2 |
158,272,383 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1718:Ralgapb
|
UTSW |
2 |
158,285,200 (GRCm39) |
nonsense |
probably null |
|
|
R1777:Ralgapb
|
UTSW |
2 |
158,304,115 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1822:Ralgapb
|
UTSW |
2 |
158,334,372 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1903:Ralgapb
|
UTSW |
2 |
158,337,483 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1909:Ralgapb
|
UTSW |
2 |
158,286,595 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2157:Ralgapb
|
UTSW |
2 |
158,279,392 (GRCm39) |
missense |
probably benign |
0.15 |
|
R4524:Ralgapb
|
UTSW |
2 |
158,279,226 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4946:Ralgapb
|
UTSW |
2 |
158,282,887 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4975:Ralgapb
|
UTSW |
2 |
158,277,428 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R5014:Ralgapb
|
UTSW |
2 |
158,337,455 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5165:Ralgapb
|
UTSW |
2 |
158,307,832 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R5465:Ralgapb
|
UTSW |
2 |
158,290,325 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5526:Ralgapb
|
UTSW |
2 |
158,274,705 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5566:Ralgapb
|
UTSW |
2 |
158,336,630 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5949:Ralgapb
|
UTSW |
2 |
158,296,179 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6140:Ralgapb
|
UTSW |
2 |
158,298,492 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6175:Ralgapb
|
UTSW |
2 |
158,288,075 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6192:Ralgapb
|
UTSW |
2 |
158,291,367 (GRCm39) |
splice site |
probably null |
|
|
R6364:Ralgapb
|
UTSW |
2 |
158,304,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6458:Ralgapb
|
UTSW |
2 |
158,286,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6746:Ralgapb
|
UTSW |
2 |
158,318,056 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6782:Ralgapb
|
UTSW |
2 |
158,278,486 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6788:Ralgapb
|
UTSW |
2 |
158,278,486 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7017:Ralgapb
|
UTSW |
2 |
158,290,257 (GRCm39) |
missense |
probably benign |
0.19 |
|
R7108:Ralgapb
|
UTSW |
2 |
158,336,582 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7108:Ralgapb
|
UTSW |
2 |
158,334,380 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7236:Ralgapb
|
UTSW |
2 |
158,282,747 (GRCm39) |
missense |
probably benign |
0.34 |
|
R7485:Ralgapb
|
UTSW |
2 |
158,285,275 (GRCm39) |
missense |
probably benign |
0.35 |
|
R7595:Ralgapb
|
UTSW |
2 |
158,268,085 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R7615:Ralgapb
|
UTSW |
2 |
158,292,190 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7728:Ralgapb
|
UTSW |
2 |
158,324,423 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7913:Ralgapb
|
UTSW |
2 |
158,307,859 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7953:Ralgapb
|
UTSW |
2 |
158,307,803 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8245:Ralgapb
|
UTSW |
2 |
158,285,256 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8337:Ralgapb
|
UTSW |
2 |
158,292,192 (GRCm39) |
missense |
probably benign |
0.11 |
|
R8363:Ralgapb
|
UTSW |
2 |
158,268,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8429:Ralgapb
|
UTSW |
2 |
158,268,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8673:Ralgapb
|
UTSW |
2 |
158,292,133 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8955:Ralgapb
|
UTSW |
2 |
158,337,389 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8955:Ralgapb
|
UTSW |
2 |
158,279,264 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8992:Ralgapb
|
UTSW |
2 |
158,296,197 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9013:Ralgapb
|
UTSW |
2 |
158,279,060 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9141:Ralgapb
|
UTSW |
2 |
158,262,811 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R9166:Ralgapb
|
UTSW |
2 |
158,274,842 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9242:Ralgapb
|
UTSW |
2 |
158,277,386 (GRCm39) |
missense |
probably benign |
0.13 |
|
R9274:Ralgapb
|
UTSW |
2 |
158,278,539 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9354:Ralgapb
|
UTSW |
2 |
158,279,313 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9454:Ralgapb
|
UTSW |
2 |
158,315,072 (GRCm39) |
missense |
probably benign |
0.30 |
|
R9489:Ralgapb
|
UTSW |
2 |
158,268,283 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9490:Ralgapb
|
UTSW |
2 |
158,334,350 (GRCm39) |
missense |
probably benign |
0.29 |
|
R9510:Ralgapb
|
UTSW |
2 |
158,285,856 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1177:Ralgapb
|
UTSW |
2 |
158,277,475 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGGCATTGCTGAGAATCTAGC -3'
(R):5'- ACACAGTTCTTTAGCCATCGTTAC -3'
Sequencing Primer
(F):5'- CATTGCTGAGAATCTAGCAGAGAAGC -3'
(R):5'- TAGAGGTTGGAGGATAACTCTCC -3'
|
| Posted On |
2019-10-07 |
Incidental Mutation