Incidental Mutation 'R7464:Fbxw10'
| ID |
578655 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Fbxw10
|
| Ensembl Gene |
ENSMUSG00000090173 |
| Gene Name |
F-box and WD-40 domain protein 10 |
| Synonyms |
SM2SH2, SM25H2, Fbw10 |
| MMRRC Submission |
045538-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.060)
|
| Stock # |
R7464 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
62737895-62768291 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 62744124 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Asparagine
at position 307
(I307N)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000135870
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000036085]
[ENSMUST00000072639]
[ENSMUST00000150989]
[ENSMUST00000176577]
[ENSMUST00000177336]
|
| AlphaFold |
Q5SUS0 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000036085
AA Change: I307N
PolyPhen 2
Score 0.008 (Sensitivity: 0.96; Specificity: 0.76)
|
| SMART Domains |
Protein: ENSMUSP00000046156
Gene: ENSMUSG00000090173
AA Change: I307N
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
262 |
274 |
N/A |
INTRINSIC |
|
Blast:FBOX
|
286 |
326 |
6e-14 |
BLAST |
|
Blast:WD40
|
416 |
453 |
2e-8 |
BLAST |
|
WD40
|
457 |
496 |
1.78e-5 |
SMART |
|
WD40
|
499 |
536 |
5.55e-7 |
SMART |
|
WD40
|
539 |
575 |
2.84e-4 |
SMART |
|
WD40
|
578 |
615 |
3.81e-5 |
SMART |
|
WD40
|
620 |
656 |
6.9e-1 |
SMART |
|
low complexity region
|
709 |
724 |
N/A |
INTRINSIC |
|
coiled coil region
|
964 |
992 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000072639
|
| SMART Domains |
Protein: ENSMUSP00000072432
Gene: ENSMUSG00000047821
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:BBOX
|
64 |
113 |
5e-24 |
BLAST |
|
BBOX
|
117 |
157 |
3.24e-4 |
SMART |
|
coiled coil region
|
171 |
196 |
N/A |
INTRINSIC |
|
coiled coil region
|
237 |
265 |
N/A |
INTRINSIC |
|
PRY
|
364 |
417 |
1.41e-22 |
SMART |
|
Pfam:SPRY
|
418 |
483 |
1.4e-6 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000150989
AA Change: I307N
PolyPhen 2
Score 0.035 (Sensitivity: 0.94; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000117872
Gene: ENSMUSG00000090173
AA Change: I307N
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
262 |
274 |
N/A |
INTRINSIC |
|
Blast:FBOX
|
286 |
326 |
1e-13 |
BLAST |
|
Blast:WD40
|
406 |
443 |
2e-8 |
BLAST |
|
WD40
|
447 |
486 |
1.78e-5 |
SMART |
|
WD40
|
489 |
526 |
5.55e-7 |
SMART |
|
WD40
|
529 |
565 |
2.84e-4 |
SMART |
|
WD40
|
568 |
605 |
3.81e-5 |
SMART |
|
WD40
|
610 |
646 |
6.9e-1 |
SMART |
|
low complexity region
|
699 |
714 |
N/A |
INTRINSIC |
|
coiled coil region
|
954 |
982 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176577
AA Change: I307N
PolyPhen 2
Score 0.014 (Sensitivity: 0.96; Specificity: 0.79)
|
| SMART Domains |
Protein: ENSMUSP00000135870
Gene: ENSMUSG00000090173
AA Change: I307N
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
262 |
274 |
N/A |
INTRINSIC |
|
Blast:FBOX
|
286 |
326 |
6e-14 |
BLAST |
|
Blast:WD40
|
406 |
443 |
2e-8 |
BLAST |
|
WD40
|
447 |
486 |
1.78e-5 |
SMART |
|
WD40
|
489 |
526 |
5.55e-7 |
SMART |
|
WD40
|
529 |
565 |
2.84e-4 |
SMART |
|
WD40
|
568 |
605 |
3.81e-5 |
SMART |
|
WD40
|
610 |
646 |
6.9e-1 |
SMART |
|
low complexity region
|
704 |
719 |
N/A |
INTRINSIC |
|
coiled coil region
|
959 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000177336
AA Change: I307N
PolyPhen 2
Score 0.019 (Sensitivity: 0.95; Specificity: 0.80)
|
| SMART Domains |
Protein: ENSMUSP00000135294
Gene: ENSMUSG00000090173
AA Change: I307N
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
262 |
274 |
N/A |
INTRINSIC |
|
Blast:FBOX
|
286 |
326 |
5e-14 |
BLAST |
|
Blast:WD40
|
406 |
443 |
1e-8 |
BLAST |
|
WD40
|
447 |
486 |
1.78e-5 |
SMART |
|
WD40
|
489 |
526 |
5.55e-7 |
SMART |
|
WD40
|
529 |
565 |
2.84e-4 |
SMART |
|
WD40
|
568 |
605 |
3.81e-5 |
SMART |
|
WD40
|
610 |
646 |
6.9e-1 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 98.9%
|
| Validation Efficiency |
96% (79/82) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 85 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aass |
C |
T |
6: 23,077,152 (GRCm39) |
G736R |
possibly damaging |
Het |
| Acta2 |
G |
A |
19: 34,229,931 (GRCm39) |
T8I |
probably benign |
Het |
| Ankar |
A |
T |
1: 72,738,053 (GRCm39) |
V43E |
possibly damaging |
Het |
| Apof |
A |
G |
10: 128,105,505 (GRCm39) |
I220V |
probably benign |
Het |
| Asxl1 |
G |
T |
2: 153,239,705 (GRCm39) |
A499S |
probably benign |
Het |
| Baz2a |
T |
A |
10: 127,957,942 (GRCm39) |
D1069E |
possibly damaging |
Het |
| Baz2b |
T |
C |
2: 59,807,792 (GRCm39) |
T156A |
possibly damaging |
Het |
| Bbc3 |
A |
T |
7: 16,051,082 (GRCm39) |
R169W |
unknown |
Het |
| C5ar1 |
T |
A |
7: 15,982,691 (GRCm39) |
I110L |
probably benign |
Het |
| Cd19 |
C |
A |
7: 126,010,975 (GRCm39) |
R323L |
probably damaging |
Het |
| Cdc14b |
A |
T |
13: 64,344,489 (GRCm39) |
C113* |
probably null |
Het |
| Cngb1 |
C |
A |
8: 95,980,811 (GRCm39) |
W914L |
possibly damaging |
Het |
| Colgalt2 |
A |
G |
1: 152,379,895 (GRCm39) |
K445E |
probably damaging |
Het |
| Crebrf |
A |
G |
17: 26,982,461 (GRCm39) |
M608V |
unknown |
Het |
| Csf1 |
T |
A |
3: 107,656,191 (GRCm39) |
H280L |
probably benign |
Het |
| Cyp2j11 |
C |
A |
4: 96,233,357 (GRCm39) |
R113L |
probably damaging |
Het |
| D5Ertd579e |
G |
A |
5: 36,771,129 (GRCm39) |
H1089Y |
probably damaging |
Het |
| Ddx60 |
C |
T |
8: 62,393,708 (GRCm39) |
T48M |
possibly damaging |
Het |
| Defa40 |
T |
A |
8: 21,739,910 (GRCm39) |
S45T |
probably damaging |
Het |
| Dock10 |
T |
C |
1: 80,518,032 (GRCm39) |
D1315G |
probably damaging |
Het |
| Dock2 |
T |
G |
11: 34,586,105 (GRCm39) |
N526H |
probably damaging |
Het |
| Dram2 |
T |
C |
3: 106,480,999 (GRCm39) |
*268Q |
probably null |
Het |
| Emc8 |
A |
G |
8: 121,394,657 (GRCm39) |
Y21H |
possibly damaging |
Het |
| Fam162a |
A |
G |
16: 35,891,863 (GRCm39) |
L4P |
probably damaging |
Het |
| Fan1 |
T |
A |
7: 64,022,234 (GRCm39) |
N340Y |
probably damaging |
Het |
| Fbxw16 |
A |
G |
9: 109,268,619 (GRCm39) |
V257A |
possibly damaging |
Het |
| Fer1l6 |
T |
A |
15: 58,445,096 (GRCm39) |
|
probably null |
Het |
| Galnt7 |
A |
G |
8: 58,037,054 (GRCm39) |
Y112H |
possibly damaging |
Het |
| Gigyf2 |
T |
C |
1: 87,356,326 (GRCm39) |
I803T |
unknown |
Het |
| Gm28729 |
A |
G |
9: 96,403,288 (GRCm39) |
I44T |
possibly damaging |
Het |
| Gm5447 |
A |
G |
13: 31,158,377 (GRCm39) |
I34V |
not run |
Het |
| H2-M9 |
A |
T |
17: 36,953,303 (GRCm39) |
|
probably null |
Het |
| Helz |
G |
A |
11: 107,527,104 (GRCm39) |
C864Y |
probably damaging |
Het |
| Il25 |
A |
G |
14: 55,170,679 (GRCm39) |
Y84C |
probably null |
Het |
| Itga10 |
T |
A |
3: 96,555,471 (GRCm39) |
C142S |
probably damaging |
Het |
| Kcna10 |
A |
T |
3: 107,101,395 (GRCm39) |
M9L |
probably damaging |
Het |
| Klhl6 |
G |
T |
16: 19,775,863 (GRCm39) |
Q232K |
possibly damaging |
Het |
| Mb21d2 |
T |
G |
16: 28,748,298 (GRCm39) |
I40L |
possibly damaging |
Het |
| Mdm1 |
T |
C |
10: 117,988,171 (GRCm39) |
S334P |
probably benign |
Het |
| Mllt10 |
T |
A |
2: 18,175,090 (GRCm39) |
D549E |
probably benign |
Het |
| Mlxipl |
T |
C |
5: 135,162,482 (GRCm39) |
V648A |
probably benign |
Het |
| Nars2 |
A |
G |
7: 96,689,137 (GRCm39) |
K353R |
probably benign |
Het |
| Nav1 |
T |
A |
1: 135,512,647 (GRCm39) |
M138L |
probably benign |
Het |
| Neb |
T |
C |
2: 52,083,902 (GRCm39) |
T5635A |
probably benign |
Het |
| Nktr |
A |
C |
9: 121,579,393 (GRCm39) |
I1154L |
unknown |
Het |
| Or14j8 |
A |
T |
17: 38,263,171 (GRCm39) |
V248D |
probably damaging |
Het |
| Or2a57 |
T |
G |
6: 43,213,228 (GRCm39) |
S229A |
probably damaging |
Het |
| Or4g17 |
T |
A |
2: 111,209,543 (GRCm39) |
L66Q |
probably damaging |
Het |
| Oxld1 |
T |
C |
11: 120,347,963 (GRCm39) |
D78G |
probably benign |
Het |
| Pde1b |
T |
C |
15: 103,433,256 (GRCm39) |
I255T |
probably benign |
Het |
| Pkp4 |
T |
A |
2: 59,138,481 (GRCm39) |
F244I |
probably benign |
Het |
| Polg2 |
C |
A |
11: 106,664,540 (GRCm39) |
V305L |
probably benign |
Het |
| Pramel34 |
C |
T |
5: 93,784,099 (GRCm39) |
C455Y |
probably damaging |
Het |
| Ptpn18 |
G |
A |
1: 34,512,445 (GRCm39) |
D417N |
possibly damaging |
Het |
| Sash1 |
T |
C |
10: 8,632,509 (GRCm39) |
D242G |
possibly damaging |
Het |
| Six4 |
T |
C |
12: 73,159,304 (GRCm39) |
T219A |
possibly damaging |
Het |
| Slc28a3 |
A |
C |
13: 58,710,835 (GRCm39) |
Y562* |
probably null |
Het |
| Soat1 |
A |
T |
1: 156,266,887 (GRCm39) |
W310R |
probably damaging |
Het |
| Son |
CATGGACTCCCAGATGTTAGCAACTAGCTCTATGGACTCCCAGATGTTAGCAACTAGCTCTATGGACTCCCAGATGTTAGCAACCAGCAGTATGGACTCCCAGATGTTAGCAACCAGCAGTATGGACTCCCAGATGTTAGCAACCAGCTCCATGGACTCCCAGATGTTAGCAAC |
CATGGACTCCCAGATGTTAGCAACTAGCTCTATGGACTCCCAGATGTTAGCAACCAGCAGTATGGACTCCCAGATGTTAGCAACCAGCAGTATGGACTCCCAGATGTTAGCAACCAGCTCCATGGACTCCCAGATGTTAGCAAC |
16: 91,453,579 (GRCm39) |
|
probably benign |
Het |
| Spef2 |
T |
C |
15: 9,740,671 (GRCm39) |
N30D |
probably benign |
Het |
| Spopfm2 |
A |
T |
3: 94,083,411 (GRCm39) |
N133K |
probably benign |
Het |
| Srebf2 |
T |
A |
15: 82,057,075 (GRCm39) |
I270N |
probably damaging |
Het |
| St8sia3 |
T |
C |
18: 64,404,589 (GRCm39) |
W289R |
probably damaging |
Het |
| Stx5a |
T |
A |
19: 8,720,868 (GRCm39) |
|
probably benign |
Het |
| Tacc1 |
T |
C |
8: 25,654,480 (GRCm39) |
D689G |
probably damaging |
Het |
| Tacc3 |
A |
G |
5: 33,818,628 (GRCm39) |
D21G |
probably benign |
Het |
| Tapt1 |
G |
A |
5: 44,346,030 (GRCm39) |
R307* |
probably null |
Het |
| Tbc1d9b |
T |
A |
11: 50,022,312 (GRCm39) |
V16E |
probably damaging |
Het |
| Tchhl1 |
G |
A |
3: 93,377,971 (GRCm39) |
R225K |
probably benign |
Het |
| Thumpd3 |
G |
A |
6: 113,032,730 (GRCm39) |
G156D |
probably benign |
Het |
| Tmem178 |
C |
T |
17: 81,252,331 (GRCm39) |
P72S |
probably benign |
Het |
| Tmem52 |
C |
T |
4: 155,553,926 (GRCm39) |
P46S |
probably benign |
Het |
| Tmem94 |
G |
T |
11: 115,677,082 (GRCm39) |
R118L |
possibly damaging |
Het |
| Tulp3 |
A |
T |
6: 128,303,792 (GRCm39) |
V269D |
probably benign |
Het |
| Ubr1 |
A |
G |
2: 120,720,255 (GRCm39) |
|
probably null |
Het |
| Upf1 |
G |
A |
8: 70,786,073 (GRCm39) |
S962L |
probably benign |
Het |
| Vcpip1 |
C |
T |
1: 9,816,745 (GRCm39) |
R546Q |
probably damaging |
Het |
| Vmn2r49 |
A |
C |
7: 9,722,820 (GRCm39) |
S151R |
probably benign |
Het |
| Wac |
T |
C |
18: 7,871,746 (GRCm39) |
|
probably null |
Het |
| Wrn |
C |
T |
8: 33,826,024 (GRCm39) |
|
probably null |
Het |
| Zfp286 |
C |
A |
11: 62,671,627 (GRCm39) |
D149Y |
probably benign |
Het |
| Zfp748 |
A |
G |
13: 67,690,091 (GRCm39) |
C390R |
probably damaging |
Het |
| Zfp873 |
A |
G |
10: 81,896,210 (GRCm39) |
T314A |
possibly damaging |
Het |
| Zfyve1 |
C |
T |
12: 83,598,261 (GRCm39) |
D656N |
probably benign |
Het |
| Zmym1 |
T |
A |
4: 126,952,728 (GRCm39) |
K18* |
probably null |
Het |
|
| Other mutations in Fbxw10 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00941:Fbxw10
|
APN |
11 |
62,764,327 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01552:Fbxw10
|
APN |
11 |
62,748,510 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL01625:Fbxw10
|
APN |
11 |
62,750,853 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01960:Fbxw10
|
APN |
11 |
62,767,582 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02457:Fbxw10
|
APN |
11 |
62,765,808 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02475:Fbxw10
|
APN |
11 |
62,748,561 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02864:Fbxw10
|
APN |
11 |
62,764,349 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0083:Fbxw10
|
UTSW |
11 |
62,767,887 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0108:Fbxw10
|
UTSW |
11 |
62,767,887 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0147:Fbxw10
|
UTSW |
11 |
62,738,307 (GRCm39) |
splice site |
probably null |
|
|
R0180:Fbxw10
|
UTSW |
11 |
62,743,922 (GRCm39) |
missense |
probably benign |
0.09 |
|
R0196:Fbxw10
|
UTSW |
11 |
62,768,070 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0454:Fbxw10
|
UTSW |
11 |
62,767,564 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R0529:Fbxw10
|
UTSW |
11 |
62,750,671 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0791:Fbxw10
|
UTSW |
11 |
62,738,282 (GRCm39) |
missense |
probably benign |
0.18 |
|
R0927:Fbxw10
|
UTSW |
11 |
62,767,770 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1026:Fbxw10
|
UTSW |
11 |
62,765,997 (GRCm39) |
missense |
probably benign |
|
|
R1448:Fbxw10
|
UTSW |
11 |
62,738,418 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R1468:Fbxw10
|
UTSW |
11 |
62,753,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1468:Fbxw10
|
UTSW |
11 |
62,753,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1689:Fbxw10
|
UTSW |
11 |
62,750,862 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1785:Fbxw10
|
UTSW |
11 |
62,750,683 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2130:Fbxw10
|
UTSW |
11 |
62,750,683 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2132:Fbxw10
|
UTSW |
11 |
62,750,683 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2211:Fbxw10
|
UTSW |
11 |
62,758,361 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3078:Fbxw10
|
UTSW |
11 |
62,758,339 (GRCm39) |
splice site |
probably benign |
|
|
R3700:Fbxw10
|
UTSW |
11 |
62,759,983 (GRCm39) |
splice site |
probably null |
|
|
R3932:Fbxw10
|
UTSW |
11 |
62,759,983 (GRCm39) |
splice site |
probably benign |
|
|
R4843:Fbxw10
|
UTSW |
11 |
62,738,151 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4869:Fbxw10
|
UTSW |
11 |
62,753,557 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4879:Fbxw10
|
UTSW |
11 |
62,738,573 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4980:Fbxw10
|
UTSW |
11 |
62,738,583 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5417:Fbxw10
|
UTSW |
11 |
62,767,990 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R5531:Fbxw10
|
UTSW |
11 |
62,753,482 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5877:Fbxw10
|
UTSW |
11 |
62,748,542 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6028:Fbxw10
|
UTSW |
11 |
62,764,345 (GRCm39) |
nonsense |
probably null |
|
|
R6616:Fbxw10
|
UTSW |
11 |
62,743,850 (GRCm39) |
missense |
probably benign |
0.14 |
|
R6870:Fbxw10
|
UTSW |
11 |
62,746,193 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6967:Fbxw10
|
UTSW |
11 |
62,738,429 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R7409:Fbxw10
|
UTSW |
11 |
62,767,606 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R7542:Fbxw10
|
UTSW |
11 |
62,741,422 (GRCm39) |
missense |
probably benign |
0.33 |
|
R7568:Fbxw10
|
UTSW |
11 |
62,765,994 (GRCm39) |
missense |
probably benign |
|
|
R7733:Fbxw10
|
UTSW |
11 |
62,764,223 (GRCm39) |
missense |
unknown |
|
|
R7793:Fbxw10
|
UTSW |
11 |
62,738,213 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R7943:Fbxw10
|
UTSW |
11 |
62,741,487 (GRCm39) |
nonsense |
probably null |
|
|
R8003:Fbxw10
|
UTSW |
11 |
62,748,587 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R8323:Fbxw10
|
UTSW |
11 |
62,767,506 (GRCm39) |
missense |
probably benign |
0.33 |
|
R8899:Fbxw10
|
UTSW |
11 |
62,748,567 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8904:Fbxw10
|
UTSW |
11 |
62,765,831 (GRCm39) |
nonsense |
probably null |
|
|
R9035:Fbxw10
|
UTSW |
11 |
62,758,449 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9121:Fbxw10
|
UTSW |
11 |
62,738,153 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9300:Fbxw10
|
UTSW |
11 |
62,768,109 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9332:Fbxw10
|
UTSW |
11 |
62,748,585 (GRCm39) |
missense |
probably benign |
0.33 |
|
R9334:Fbxw10
|
UTSW |
11 |
62,765,910 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R9417:Fbxw10
|
UTSW |
11 |
62,753,522 (GRCm39) |
nonsense |
probably null |
|
|
R9476:Fbxw10
|
UTSW |
11 |
62,743,814 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9510:Fbxw10
|
UTSW |
11 |
62,743,814 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9520:Fbxw10
|
UTSW |
11 |
62,750,842 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R9526:Fbxw10
|
UTSW |
11 |
62,765,945 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R9547:Fbxw10
|
UTSW |
11 |
62,767,647 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R9602:Fbxw10
|
UTSW |
11 |
62,750,782 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
Z1186:Fbxw10
|
UTSW |
11 |
62,767,671 (GRCm39) |
missense |
probably benign |
|
|
Z1186:Fbxw10
|
UTSW |
11 |
62,738,118 (GRCm39) |
missense |
probably benign |
|
|
Z1187:Fbxw10
|
UTSW |
11 |
62,767,671 (GRCm39) |
missense |
probably benign |
|
|
Z1187:Fbxw10
|
UTSW |
11 |
62,738,118 (GRCm39) |
missense |
probably benign |
|
|
Z1188:Fbxw10
|
UTSW |
11 |
62,767,671 (GRCm39) |
missense |
probably benign |
|
|
Z1188:Fbxw10
|
UTSW |
11 |
62,738,118 (GRCm39) |
missense |
probably benign |
|
|
Z1189:Fbxw10
|
UTSW |
11 |
62,767,671 (GRCm39) |
missense |
probably benign |
|
|
Z1189:Fbxw10
|
UTSW |
11 |
62,738,118 (GRCm39) |
missense |
probably benign |
|
|
Z1190:Fbxw10
|
UTSW |
11 |
62,767,671 (GRCm39) |
missense |
probably benign |
|
|
Z1190:Fbxw10
|
UTSW |
11 |
62,738,118 (GRCm39) |
missense |
probably benign |
|
|
Z1191:Fbxw10
|
UTSW |
11 |
62,767,671 (GRCm39) |
missense |
probably benign |
|
|
Z1191:Fbxw10
|
UTSW |
11 |
62,738,118 (GRCm39) |
missense |
probably benign |
|
|
Z1192:Fbxw10
|
UTSW |
11 |
62,767,671 (GRCm39) |
missense |
probably benign |
|
|
Z1192:Fbxw10
|
UTSW |
11 |
62,738,118 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TCTGGGTACAGCAAATATCGG -3'
(R):5'- GCGACATTTTGGGGAGTCTAC -3'
Sequencing Primer
(F):5'- TCGGGACTTTATACGCGAC -3'
(R):5'- GTCTACCCTGGAGACACAAAGGTTC -3'
|
| Posted On |
2019-10-07 |
Incidental Mutation