Mutagenetix > Incidental Mutation

Incidental Mutation 'R7466:Ryr3'

578749

Institutional Source

Beutler Lab

Gene Symbol

Ryr3

Ensembl Gene

ENSMUSG00000057378

Gene Name

ryanodine receptor 3

Synonyms

calcium release channel isoform 3

MMRRC Submission

045540-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.368) question?

Stock #

R7466 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

112631355-113217096 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 112926957 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Glycine at position 351 (D351G)

Ref Sequence

ENSEMBL: ENSMUSP00000089426 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000080673] [ENSMUST00000091818] [ENSMUST00000134358] [ENSMUST00000208151] [ENSMUST00000208290]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000080673
AA Change: D331G

PolyPhen 2 Score 0.705 (Sensitivity: 0.86; Specificity: 0.92)

SMART Domains

Protein: ENSMUSP00000079503
Gene: ENSMUSG00000057378
AA Change: D331G

Domain	Start	End	E-Value	Type
low complexity region	90	99	N/A	INTRINSIC
MIR	100	155	3.27e-4	SMART
MIR	162	207	7.52e-4	SMART
MIR	215	269	8.06e-4	SMART
MIR	275	368	8.4e-25	SMART
Pfam:RYDR_ITPR	438	642	1.1e-71	PFAM
SPRY	657	795	1.16e-24	SMART
Pfam:RyR	848	942	1.5e-34	PFAM
Pfam:RyR	962	1056	1.2e-32	PFAM
SPRY	1084	1207	7.99e-37	SMART
SPRY	1325	1465	6.25e-30	SMART
low complexity region	1757	1772	N/A	INTRINSIC
low complexity region	1773	1788	N/A	INTRINSIC
low complexity region	1932	1957	N/A	INTRINSIC
Pfam:RYDR_ITPR	2018	2228	1.8e-59	PFAM
Pfam:RyR	2595	2689	1.2e-36	PFAM
Pfam:RyR	2713	2801	2.1e-31	PFAM
low complexity region	2877	2887	N/A	INTRINSIC
low complexity region	3169	3184	N/A	INTRINSIC
low complexity region	3327	3338	N/A	INTRINSIC
PDB:2BCX\|B	3462	3491	9e-12	PDB
low complexity region	3532	3540	N/A	INTRINSIC
coiled coil region	3585	3614	N/A	INTRINSIC
Pfam:RIH_assoc	3715	3848	4.9e-40	PFAM
low complexity region	3855	3875	N/A	INTRINSIC
SCOP:d1sra__	3893	3989	1e-10	SMART
low complexity region	4096	4134	N/A	INTRINSIC
transmembrane domain	4178	4200	N/A	INTRINSIC
Pfam:RR_TM4-6	4227	4497	4.7e-96	PFAM
Pfam:Ion_trans	4599	4762	2e-11	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000091818
AA Change: D351G

PolyPhen 2 Score 0.400 (Sensitivity: 0.89; Specificity: 0.89)

SMART Domains

Protein: ENSMUSP00000089426
Gene: ENSMUSG00000057378
AA Change: D351G

Domain	Start	End	E-Value	Type
low complexity region	110	119	N/A	INTRINSIC
MIR	120	175	3.27e-4	SMART
MIR	182	227	7.52e-4	SMART
MIR	235	289	8.06e-4	SMART
MIR	295	388	8.4e-25	SMART
Pfam:RYDR_ITPR	460	655	1.2e-64	PFAM
SPRY	677	815	1.16e-24	SMART
Pfam:RyR	869	959	3.3e-38	PFAM
Pfam:RyR	983	1073	2.5e-32	PFAM
SPRY	1104	1227	7.99e-37	SMART
SPRY	1345	1485	6.25e-30	SMART
low complexity region	1777	1792	N/A	INTRINSIC
low complexity region	1793	1808	N/A	INTRINSIC
low complexity region	1952	1977	N/A	INTRINSIC
Pfam:RYDR_ITPR	2040	2248	5.8e-67	PFAM
Pfam:RyR	2616	2706	6.3e-33	PFAM
Pfam:RyR	2734	2818	6.6e-26	PFAM
low complexity region	2897	2907	N/A	INTRINSIC
low complexity region	3189	3204	N/A	INTRINSIC
PDB:2BCX\|B	3487	3516	1e-11	PDB
low complexity region	3557	3565	N/A	INTRINSIC
coiled coil region	3610	3639	N/A	INTRINSIC
Pfam:RIH_assoc	3744	3862	3.5e-34	PFAM
low complexity region	3880	3900	N/A	INTRINSIC
SCOP:d1sra__	3918	4014	1e-10	SMART
low complexity region	4121	4159	N/A	INTRINSIC
transmembrane domain	4203	4225	N/A	INTRINSIC
Pfam:RR_TM4-6	4252	4522	1.1e-98	PFAM
Pfam:Ion_trans	4625	4799	6.2e-16	PFAM

Predicted Effect

possibly damaging
Transcript: ENSMUST00000134358
AA Change: D331G

PolyPhen 2 Score 0.775 (Sensitivity: 0.85; Specificity: 0.92)

Predicted Effect

possibly damaging
Transcript: ENSMUST00000208151
AA Change: D331G

PolyPhen 2 Score 0.862 (Sensitivity: 0.83; Specificity: 0.93)

Predicted Effect

probably benign
Transcript: ENSMUST00000208290
AA Change: D331G

PolyPhen 2 Score 0.448 (Sensitivity: 0.89; Specificity: 0.90)

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.8%
20x: 99.2%

Validation Efficiency

99% (83/84)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a ryanodine receptor, which functions to release calcium from intracellular storage for use in many cellular processes. For example, the encoded protein is involved in skeletal muscle contraction by releasing calcium from the sarcoplasmic reticulum followed by depolarization of T-tubules. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
PHENOTYPE: Homozygotes for targeted null mutations exhibit impaired muscle contraction at an early age, changes in hippocampal synaptic plasticity, increased locomotor activity with a tendency to circle, and impaired relearning of a spatial task. [provided by MGI curators]

Allele List at MGI

All alleles(10) : Targeted, knock-out(5) Targeted, other(2) Gene trapped(3)

Other mutations in this stock

Total: 83 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
AI182371	T	A	2: 35,088,741 (GRCm38)	K203*	probably null	Het
Akr1c13	T	C	13: 4,192,437 (GRCm38)		probably benign	Het
Amer3	A	G	1: 34,587,993 (GRCm38)	S438G	probably damaging	Het
Aqp9	T	A	9: 71,163,261 (GRCm38)		probably null	Het
Art4	G	T	6: 136,854,850 (GRCm38)	H98N	probably damaging	Het
Bdh1	T	C	16: 31,447,604 (GRCm38)	S70P	probably benign	Het
Ccdc61	A	C	7: 18,891,105 (GRCm38)	Y503D	probably damaging	Het
Cd163l1	T	C	7: 140,220,706 (GRCm38)		probably null	Het
Cd180	A	T	13: 102,704,995 (GRCm38)	N183I	probably damaging	Het
Cd200r2	C	T	16: 44,909,174 (GRCm38)	A64V	probably damaging	Het
Ceacam9	A	C	7: 16,723,855 (GRCm38)	K98Q	probably benign	Het
Cep44	AACGC	A	8: 56,540,983 (GRCm38)		probably null	Het
Cfap77	G	T	2: 28,955,613 (GRCm38)	D247E	probably benign	Het
Cftr	T	C	6: 18,227,973 (GRCm38)	M388T	probably benign	Het
Chrnb1	G	A	11: 69,784,650 (GRCm38)	H493Y	probably damaging	Het
Ckap2	A	C	8: 22,177,386 (GRCm38)	M153R	probably benign	Het
Cnot6l	A	G	5: 96,131,128 (GRCm38)	V77A	probably benign	Het
Col12a1	C	T	9: 79,655,407 (GRCm38)	E1798K	possibly damaging	Het
Cth	T	A	3: 157,924,885 (GRCm38)	D49V	probably benign	Het
Ctnnb1	T	C	9: 120,955,416 (GRCm38)	S425P	probably damaging	Het
Ctnnd1	T	C	2: 84,610,785 (GRCm38)	N690S	probably benign	Het
Cyhr1	C	T	15: 76,648,186 (GRCm38)	D241N	probably benign	Het
Dennd4c	A	G	4: 86,774,331 (GRCm38)	D26G	probably damaging	Het
Dlg5	G	A	14: 24,245,212 (GRCm38)	P80L	probably damaging	Het
Eef2k	A	G	7: 120,903,484 (GRCm38)		probably null	Het
Ephb2	C	T	4: 136,659,065 (GRCm38)	R791H	probably damaging	Het
Erh	T	C	12: 80,640,983 (GRCm38)	Y22C	probably benign	Het
F5	C	T	1: 164,193,328 (GRCm38)	T1124I	possibly damaging	Het
Fam220a	T	A	5: 143,563,471 (GRCm38)	C213S	possibly damaging	Het
Fat2	G	T	11: 55,310,432 (GRCm38)	N605K	probably damaging	Het
Ganab	C	A	19: 8,914,569 (GRCm38)	S780*	probably null	Het
Gbgt1	C	T	2: 28,502,207 (GRCm38)	P67S	probably damaging	Het
Gm17190	G	T	13: 96,082,779 (GRCm38)	G208*	probably null	Het
Grhl2	A	G	15: 37,291,616 (GRCm38)	Y316C	probably damaging	Het
H2-T10	T	C	17: 36,120,849 (GRCm38)	T38A	probably benign	Het
Ins1	A	G	19: 52,264,420 (GRCm38)		probably benign	Het
Ippk	T	C	13: 49,432,467 (GRCm38)		probably null	Het
Klc4	T	A	17: 46,639,910 (GRCm38)	I258F	probably benign	Het
Manba	C	A	3: 135,542,393 (GRCm38)	L348I	probably benign	Het
Mgam	A	G	6: 40,744,789 (GRCm38)	N347S	probably benign	Het
Myo18b	T	C	5: 112,723,892 (GRCm38)	T2108A	probably benign	Het
Naip5	A	T	13: 100,221,986 (GRCm38)	L914*	probably null	Het
Nsa2	C	T	13: 97,131,220 (GRCm38)	A242T	probably benign	Het
Nsd2	G	A	5: 33,882,147 (GRCm38)	W834*	probably null	Het
Olfr1134	T	C	2: 87,656,396 (GRCm38)	N175S	possibly damaging	Het
Olfr1419	T	A	19: 11,870,316 (GRCm38)	D300V	possibly damaging	Het
Olfr285	T	C	15: 98,313,380 (GRCm38)	M57V	probably damaging	Het
Olfr469	A	T	7: 107,822,922 (GRCm38)	C182*	probably null	Het
Pam	A	T	1: 97,842,247 (GRCm38)	D599E	probably damaging	Het
Phf20l1	A	G	15: 66,636,884 (GRCm38)	K864R	probably damaging	Het
Plcl2	A	G	17: 50,608,468 (GRCm38)	D835G	probably damaging	Het
Ppm1m	C	A	9: 106,196,157 (GRCm38)	A329S	probably damaging	Het
Prep	T	C	10: 45,150,438 (GRCm38)	V486A	probably benign	Het
Prkcb	A	T	7: 122,516,844 (GRCm38)	N182I	probably damaging	Het
Prkcz	A	G	4: 155,271,602 (GRCm38)	F355S	probably damaging	Het
Psg20	C	T	7: 18,684,467 (GRCm38)	S125N	probably benign	Het
Psmd12	A	G	11: 107,492,057 (GRCm38)	D234G	probably benign	Het
Pvrig	A	T	5: 138,342,008 (GRCm38)	M14L	probably benign	Het
Rabgap1l	C	T	1: 160,226,484 (GRCm38)		probably null	Het
Rfc1	A	T	5: 65,275,426 (GRCm38)	C764S	probably damaging	Het
Serpinb9g	T	C	13: 33,495,167 (GRCm38)	F340S	probably benign	Het
Sirpb1c	C	A	3: 15,832,266 (GRCm38)	L315F	probably damaging	Het
Slc24a1	C	G	9: 64,928,404 (GRCm38)	E814Q	unknown	Het
Slc26a11	A	T	11: 119,374,502 (GRCm38)	Q355L	probably damaging	Het
Sp100	C	T	1: 85,707,239 (GRCm38)	L483F	possibly damaging	Het
St5	A	G	7: 109,525,346 (GRCm38)	L1096P	probably damaging	Het
Ston1	T	A	17: 88,635,901 (GRCm38)	M245K	probably benign	Het
Swap70	T	A	7: 110,274,772 (GRCm38)	D442E	probably benign	Het
Syne2	T	A	12: 76,046,186 (GRCm38)	V450D	possibly damaging	Het
Tbck	T	A	3: 132,752,563 (GRCm38)	N651K	probably damaging	Het
Timd4	A	T	11: 46,817,758 (GRCm38)	T204S	probably benign	Het
Tmem102	A	G	11: 69,804,885 (GRCm38)	L87P	probably damaging	Het
Tmem55a	T	A	4: 14,912,477 (GRCm38)	Y195*	probably null	Het
Tmprss11e	T	A	5: 86,709,480 (GRCm38)	T325S	probably benign	Het
Trpm1	G	A	7: 64,240,582 (GRCm38)	V978M	probably damaging	Het
Wdr12	A	T	1: 60,094,511 (GRCm38)	D19E	probably benign	Het
Wdr35	G	A	12: 9,005,773 (GRCm38)	V482I	probably benign	Het
Wdr63	T	C	3: 146,055,618 (GRCm38)	D661G	probably benign	Het
Zer1	T	C	2: 30,101,484 (GRCm38)		probably null	Het
Zfp503	T	C	14: 21,986,011 (GRCm38)	D279G	probably benign	Het
Zfp870	A	T	17: 32,883,762 (GRCm38)	C198S	possibly damaging	Het
Zfyve26	C	T	12: 79,287,807 (GRCm38)	E146K	probably benign	Het
Zkscan6	T	C	11: 65,828,531 (GRCm38)	V459A	probably damaging	Het

Other mutations in Ryr3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00435:Ryr3	APN	2	112,660,149 (GRCm38)	missense	probably damaging	0.98
IGL00531:Ryr3	APN	2	112,663,012 (GRCm38)	splice site	probably benign
IGL00785:Ryr3	APN	2	112,836,103 (GRCm38)	missense	possibly damaging	0.95
IGL00901:Ryr3	APN	2	112,886,589 (GRCm38)	missense	probably damaging	1.00
IGL00910:Ryr3	APN	2	112,728,934 (GRCm38)	splice site	probably benign
IGL00970:Ryr3	APN	2	112,764,676 (GRCm38)	missense	probably damaging	1.00
IGL01083:Ryr3	APN	2	112,751,846 (GRCm38)	splice site	probably benign
IGL01105:Ryr3	APN	2	112,751,805 (GRCm38)	missense	probably damaging	1.00
IGL01287:Ryr3	APN	2	112,709,073 (GRCm38)	missense	probably damaging	1.00
IGL01343:Ryr3	APN	2	112,660,054 (GRCm38)	missense	probably damaging	1.00
IGL01472:Ryr3	APN	2	112,672,248 (GRCm38)	missense	probably benign	0.20
IGL01552:Ryr3	APN	2	112,825,883 (GRCm38)	missense	possibly damaging	0.53
IGL01594:Ryr3	APN	2	112,772,728 (GRCm38)	missense	probably damaging	1.00
IGL01723:Ryr3	APN	2	112,650,111 (GRCm38)	critical splice donor site	probably null
IGL01837:Ryr3	APN	2	112,801,320 (GRCm38)	missense	probably damaging	1.00
IGL01868:Ryr3	APN	2	112,803,158 (GRCm38)	splice site	probably benign
IGL01907:Ryr3	APN	2	112,869,001 (GRCm38)	splice site	probably benign
IGL02005:Ryr3	APN	2	112,663,263 (GRCm38)	splice site	probably benign
IGL02014:Ryr3	APN	2	112,946,915 (GRCm38)	missense	possibly damaging	0.86
IGL02109:Ryr3	APN	2	112,949,157 (GRCm38)	missense	probably benign
IGL02178:Ryr3	APN	2	112,825,799 (GRCm38)	missense	probably benign	0.17
IGL02185:Ryr3	APN	2	112,967,203 (GRCm38)	missense	probably damaging	0.99
IGL02189:Ryr3	APN	2	112,754,838 (GRCm38)	splice site	probably benign
IGL02200:Ryr3	APN	2	112,849,510 (GRCm38)	missense	probably damaging	0.98
IGL02302:Ryr3	APN	2	112,964,356 (GRCm38)	missense	probably damaging	1.00
IGL02305:Ryr3	APN	2	112,645,277 (GRCm38)	missense	probably damaging	0.96
IGL02306:Ryr3	APN	2	112,834,114 (GRCm38)	missense	probably damaging	0.98
IGL02306:Ryr3	APN	2	112,847,399 (GRCm38)	critical splice donor site	probably null
IGL02340:Ryr3	APN	2	112,947,004 (GRCm38)	splice site	probably benign
IGL02398:Ryr3	APN	2	112,847,422 (GRCm38)	missense	probably benign	0.05
IGL02407:Ryr3	APN	2	112,754,958 (GRCm38)	missense	probably damaging	1.00
IGL02426:Ryr3	APN	2	112,900,905 (GRCm38)	missense	possibly damaging	0.59
IGL02452:Ryr3	APN	2	112,833,990 (GRCm38)	missense	probably damaging	1.00
IGL02453:Ryr3	APN	2	112,681,728 (GRCm38)	splice site	probably benign
IGL02585:Ryr3	APN	2	112,712,303 (GRCm38)	missense	probably damaging	1.00
IGL02724:Ryr3	APN	2	112,902,576 (GRCm38)	critical splice donor site	probably null
IGL02817:Ryr3	APN	2	112,844,623 (GRCm38)	critical splice donor site	probably null
IGL02861:Ryr3	APN	2	112,652,841 (GRCm38)	missense	possibly damaging	0.89
IGL03038:Ryr3	APN	2	112,668,120 (GRCm38)	missense	possibly damaging	0.83
IGL03059:Ryr3	APN	2	112,800,047 (GRCm38)	missense	probably damaging	1.00
IGL03136:Ryr3	APN	2	112,675,974 (GRCm38)	splice site	probably benign
IGL03137:Ryr3	APN	2	112,910,397 (GRCm38)	missense	probably benign
IGL03166:Ryr3	APN	2	112,641,112 (GRCm38)	nonsense	probably null
IGL03177:Ryr3	APN	2	113,028,671 (GRCm38)	missense	probably benign	0.39
IGL03205:Ryr3	APN	2	112,632,142 (GRCm38)	missense	probably damaging	1.00
IGL03224:Ryr3	APN	2	112,954,336 (GRCm38)	nonsense	probably null
IGL03249:Ryr3	APN	2	112,640,656 (GRCm38)	missense	probably benign	0.32
IGL03370:Ryr3	APN	2	112,756,599 (GRCm38)	missense	possibly damaging	0.69
intruder	UTSW	2	112,672,246 (GRCm38)	nonsense	probably null
usurper	UTSW	2	112,800,022 (GRCm38)	missense	probably damaging	1.00
ANU74:Ryr3	UTSW	2	112,831,230 (GRCm38)	critical splice acceptor site	probably null
BB006:Ryr3	UTSW	2	112,834,188 (GRCm38)	missense	probably benign	0.00
BB016:Ryr3	UTSW	2	112,834,188 (GRCm38)	missense	probably benign	0.00
F5426:Ryr3	UTSW	2	112,766,338 (GRCm38)	splice site	probably benign
PIT4494001:Ryr3	UTSW	2	112,841,876 (GRCm38)	missense	probably damaging	0.99
R0022:Ryr3	UTSW	2	112,640,666 (GRCm38)	missense	probably damaging	1.00
R0022:Ryr3	UTSW	2	112,640,666 (GRCm38)	missense	probably damaging	1.00
R0051:Ryr3	UTSW	2	112,869,075 (GRCm38)	missense	probably damaging	1.00
R0051:Ryr3	UTSW	2	112,869,075 (GRCm38)	missense	probably damaging	1.00
R0085:Ryr3	UTSW	2	112,859,763 (GRCm38)	missense	probably damaging	1.00
R0097:Ryr3	UTSW	2	112,800,055 (GRCm38)	missense	probably damaging	1.00
R0097:Ryr3	UTSW	2	112,800,055 (GRCm38)	missense	probably damaging	1.00
R0098:Ryr3	UTSW	2	112,901,031 (GRCm38)	missense	probably damaging	1.00
R0098:Ryr3	UTSW	2	112,901,031 (GRCm38)	missense	probably damaging	1.00
R0116:Ryr3	UTSW	2	112,803,165 (GRCm38)	missense	probably damaging	0.99
R0281:Ryr3	UTSW	2	112,686,810 (GRCm38)	missense	probably damaging	1.00
R0302:Ryr3	UTSW	2	112,647,123 (GRCm38)	splice site	probably benign
R0306:Ryr3	UTSW	2	112,775,655 (GRCm38)	critical splice donor site	probably null
R0445:Ryr3	UTSW	2	112,866,054 (GRCm38)	missense	probably benign	0.16
R0463:Ryr3	UTSW	2	112,661,701 (GRCm38)	missense	probably damaging	1.00
R0592:Ryr3	UTSW	2	112,678,481 (GRCm38)	missense	probably damaging	1.00
R0622:Ryr3	UTSW	2	112,662,555 (GRCm38)	missense	probably damaging	1.00
R0656:Ryr3	UTSW	2	112,648,306 (GRCm38)	splice site	probably benign
R0735:Ryr3	UTSW	2	112,732,982 (GRCm38)	missense	probably benign	0.11
R0783:Ryr3	UTSW	2	112,756,327 (GRCm38)	splice site	probably benign
R0789:Ryr3	UTSW	2	112,780,973 (GRCm38)	splice site	probably null
R0835:Ryr3	UTSW	2	112,650,138 (GRCm38)	missense	probably benign	0.16
R0879:Ryr3	UTSW	2	113,030,243 (GRCm38)	missense	probably benign	0.02
R0924:Ryr3	UTSW	2	112,841,833 (GRCm38)	missense	probably damaging	1.00
R0930:Ryr3	UTSW	2	112,841,833 (GRCm38)	missense	probably damaging	1.00
R0931:Ryr3	UTSW	2	112,653,702 (GRCm38)	missense	probably damaging	1.00
R1037:Ryr3	UTSW	2	112,869,108 (GRCm38)	missense	probably benign	0.42
R1169:Ryr3	UTSW	2	112,733,014 (GRCm38)	missense	probably benign	0.01
R1170:Ryr3	UTSW	2	112,946,987 (GRCm38)	missense	probably damaging	1.00
R1178:Ryr3	UTSW	2	112,964,380 (GRCm38)	missense	probably benign	0.00
R1187:Ryr3	UTSW	2	112,958,176 (GRCm38)	missense	probably damaging	1.00
R1289:Ryr3	UTSW	2	112,645,285 (GRCm38)	missense	probably damaging	1.00
R1337:Ryr3	UTSW	2	112,779,963 (GRCm38)	missense	possibly damaging	0.46
R1342:Ryr3	UTSW	2	112,750,803 (GRCm38)	missense	probably damaging	1.00
R1349:Ryr3	UTSW	2	112,834,201 (GRCm38)	missense	probably damaging	1.00
R1372:Ryr3	UTSW	2	112,834,201 (GRCm38)	missense	probably damaging	1.00
R1434:Ryr3	UTSW	2	112,645,259 (GRCm38)	missense	probably damaging	1.00
R1438:Ryr3	UTSW	2	112,757,701 (GRCm38)	missense	probably benign	0.18
R1467:Ryr3	UTSW	2	112,753,002 (GRCm38)	splice site	probably benign
R1470:Ryr3	UTSW	2	112,653,007 (GRCm38)	missense	probably benign
R1470:Ryr3	UTSW	2	112,653,007 (GRCm38)	missense	probably benign
R1474:Ryr3	UTSW	2	112,909,962 (GRCm38)	missense	probably damaging	1.00
R1481:Ryr3	UTSW	2	112,636,522 (GRCm38)	splice site	probably benign
R1513:Ryr3	UTSW	2	112,709,197 (GRCm38)	nonsense	probably null
R1524:Ryr3	UTSW	2	112,869,082 (GRCm38)	missense	probably damaging	0.98
R1525:Ryr3	UTSW	2	112,678,090 (GRCm38)	missense	probably damaging	1.00
R1526:Ryr3	UTSW	2	112,661,657 (GRCm38)	missense	probably damaging	1.00
R1611:Ryr3	UTSW	2	112,653,505 (GRCm38)	missense	possibly damaging	0.72
R1640:Ryr3	UTSW	2	112,900,833 (GRCm38)	missense	probably damaging	1.00
R1662:Ryr3	UTSW	2	112,709,273 (GRCm38)	missense	probably damaging	0.99
R1764:Ryr3	UTSW	2	112,860,460 (GRCm38)	missense	probably damaging	1.00
R1769:Ryr3	UTSW	2	112,751,768 (GRCm38)	critical splice donor site	probably null
R1776:Ryr3	UTSW	2	112,957,253 (GRCm38)	missense	probably damaging	0.99
R1780:Ryr3	UTSW	2	112,867,292 (GRCm38)	missense	probably damaging	0.98
R1840:Ryr3	UTSW	2	112,750,820 (GRCm38)	missense	probably damaging	1.00
R1864:Ryr3	UTSW	2	112,730,328 (GRCm38)	missense	possibly damaging	0.65
R1872:Ryr3	UTSW	2	112,709,137 (GRCm38)	missense	possibly damaging	0.94
R1960:Ryr3	UTSW	2	112,794,467 (GRCm38)	missense	probably damaging	1.00
R1994:Ryr3	UTSW	2	112,654,492 (GRCm38)	missense	probably null	0.93
R2018:Ryr3	UTSW	2	112,781,065 (GRCm38)	missense	probably benign	0.24
R2019:Ryr3	UTSW	2	112,781,065 (GRCm38)	missense	probably benign	0.24
R2029:Ryr3	UTSW	2	112,647,016 (GRCm38)	missense	possibly damaging	0.82
R2051:Ryr3	UTSW	2	112,756,641 (GRCm38)	missense	probably damaging	1.00
R2060:Ryr3	UTSW	2	112,954,364 (GRCm38)	missense	possibly damaging	0.92
R2061:Ryr3	UTSW	2	112,663,004 (GRCm38)	missense	possibly damaging	0.83
R2067:Ryr3	UTSW	2	112,946,957 (GRCm38)	missense	probably damaging	1.00
R2106:Ryr3	UTSW	2	112,638,129 (GRCm38)	missense	probably damaging	1.00
R2129:Ryr3	UTSW	2	112,678,370 (GRCm38)	splice site	probably benign
R2140:Ryr3	UTSW	2	112,875,148 (GRCm38)	missense	probably benign	0.01
R2176:Ryr3	UTSW	2	112,666,335 (GRCm38)	missense	possibly damaging	0.48
R2241:Ryr3	UTSW	2	112,801,392 (GRCm38)	missense	probably damaging	1.00
R2261:Ryr3	UTSW	2	112,675,873 (GRCm38)	missense	probably damaging	0.99
R2262:Ryr3	UTSW	2	112,675,873 (GRCm38)	missense	probably damaging	0.99
R2276:Ryr3	UTSW	2	112,649,319 (GRCm38)	missense	possibly damaging	0.79
R2279:Ryr3	UTSW	2	112,649,319 (GRCm38)	missense	possibly damaging	0.79
R2403:Ryr3	UTSW	2	112,686,628 (GRCm38)	missense	probably damaging	1.00
R2510:Ryr3	UTSW	2	112,675,904 (GRCm38)	missense	probably benign	0.18
R2568:Ryr3	UTSW	2	112,675,874 (GRCm38)	missense	probably damaging	1.00
R3013:Ryr3	UTSW	2	112,640,281 (GRCm38)	missense	probably damaging	1.00
R3431:Ryr3	UTSW	2	112,656,531 (GRCm38)	missense	probably damaging	1.00
R3552:Ryr3	UTSW	2	112,751,787 (GRCm38)	missense	probably damaging	1.00
R3761:Ryr3	UTSW	2	112,754,913 (GRCm38)	missense	probably benign
R3909:Ryr3	UTSW	2	112,636,608 (GRCm38)	missense	probably damaging	1.00
R3923:Ryr3	UTSW	2	112,841,873 (GRCm38)	missense	possibly damaging	0.92
R3924:Ryr3	UTSW	2	113,028,703 (GRCm38)	splice site	probably benign
R3927:Ryr3	UTSW	2	112,675,873 (GRCm38)	missense	probably damaging	0.99
R3947:Ryr3	UTSW	2	112,675,873 (GRCm38)	missense	probably damaging	0.99
R3949:Ryr3	UTSW	2	112,675,873 (GRCm38)	missense	probably damaging	0.99
R3976:Ryr3	UTSW	2	112,675,837 (GRCm38)	missense	possibly damaging	0.49
R4004:Ryr3	UTSW	2	112,675,873 (GRCm38)	missense	probably damaging	0.99
R4022:Ryr3	UTSW	2	112,675,873 (GRCm38)	missense	probably damaging	0.99
R4084:Ryr3	UTSW	2	112,900,908 (GRCm38)	missense	probably damaging	0.99
R4106:Ryr3	UTSW	2	112,675,873 (GRCm38)	missense	probably damaging	0.99
R4108:Ryr3	UTSW	2	112,675,873 (GRCm38)	missense	probably damaging	0.99
R4109:Ryr3	UTSW	2	112,675,873 (GRCm38)	missense	probably damaging	0.99
R4131:Ryr3	UTSW	2	112,926,983 (GRCm38)	splice site	probably null
R4156:Ryr3	UTSW	2	112,653,675 (GRCm38)	missense	probably damaging	1.00
R4172:Ryr3	UTSW	2	112,794,470 (GRCm38)	missense	probably damaging	1.00
R4234:Ryr3	UTSW	2	112,910,407 (GRCm38)	missense	probably damaging	1.00
R4399:Ryr3	UTSW	2	112,946,844 (GRCm38)	missense	probably benign	0.01
R4409:Ryr3	UTSW	2	112,730,308 (GRCm38)	missense	probably damaging	1.00
R4418:Ryr3	UTSW	2	112,831,224 (GRCm38)	missense	probably damaging	1.00
R4466:Ryr3	UTSW	2	112,653,102 (GRCm38)	missense	possibly damaging	0.92
R4525:Ryr3	UTSW	2	112,653,621 (GRCm38)	missense	probably damaging	0.98
R4573:Ryr3	UTSW	2	112,755,174 (GRCm38)	splice site	probably null
R4589:Ryr3	UTSW	2	112,875,133 (GRCm38)	missense	probably damaging	1.00
R4653:Ryr3	UTSW	2	112,652,763 (GRCm38)	missense	probably damaging	1.00
R4664:Ryr3	UTSW	2	112,996,555 (GRCm38)	intron	probably benign
R4710:Ryr3	UTSW	2	112,766,301 (GRCm38)	missense	probably damaging	1.00
R4734:Ryr3	UTSW	2	112,910,502 (GRCm38)	missense	probably damaging	0.99
R4741:Ryr3	UTSW	2	112,803,268 (GRCm38)	missense	probably damaging	0.99
R4748:Ryr3	UTSW	2	112,964,405 (GRCm38)	missense	possibly damaging	0.95
R4749:Ryr3	UTSW	2	112,964,405 (GRCm38)	missense	possibly damaging	0.95
R4754:Ryr3	UTSW	2	112,757,639 (GRCm38)	missense	possibly damaging	0.94
R4764:Ryr3	UTSW	2	112,733,031 (GRCm38)	critical splice acceptor site	probably null
R4812:Ryr3	UTSW	2	112,912,236 (GRCm38)	missense	probably damaging	1.00
R4822:Ryr3	UTSW	2	112,652,745 (GRCm38)	missense	probably damaging	1.00
R4841:Ryr3	UTSW	2	112,648,373 (GRCm38)	missense	probably damaging	1.00
R4849:Ryr3	UTSW	2	112,908,462 (GRCm38)	missense	probably damaging	1.00
R4917:Ryr3	UTSW	2	112,831,185 (GRCm38)	missense	probably damaging	1.00
R4942:Ryr3	UTSW	2	112,836,257 (GRCm38)	missense	probably damaging	0.99
R4990:Ryr3	UTSW	2	112,909,973 (GRCm38)	missense	probably damaging	1.00
R4990:Ryr3	UTSW	2	112,635,777 (GRCm38)	missense	probably damaging	1.00
R5049:Ryr3	UTSW	2	112,640,171 (GRCm38)	missense	probably damaging	1.00
R5055:Ryr3	UTSW	2	112,831,159 (GRCm38)	missense	probably benign	0.00
R5112:Ryr3	UTSW	2	112,902,665 (GRCm38)	missense	probably damaging	1.00
R5160:Ryr3	UTSW	2	112,646,927 (GRCm38)	missense	probably damaging	1.00
R5169:Ryr3	UTSW	2	112,670,660 (GRCm38)	missense	possibly damaging	0.63
R5176:Ryr3	UTSW	2	112,757,667 (GRCm38)	missense	possibly damaging	0.95
R5182:Ryr3	UTSW	2	112,755,150 (GRCm38)	missense	probably damaging	1.00
R5206:Ryr3	UTSW	2	112,844,711 (GRCm38)	missense	probably damaging	1.00
R5263:Ryr3	UTSW	2	112,718,002 (GRCm38)	missense	possibly damaging	0.65
R5272:Ryr3	UTSW	2	112,653,213 (GRCm38)	missense	probably damaging	1.00
R5332:Ryr3	UTSW	2	112,902,693 (GRCm38)	missense	probably damaging	1.00
R5340:Ryr3	UTSW	2	112,834,125 (GRCm38)	missense	probably damaging	0.99
R5359:Ryr3	UTSW	2	112,775,841 (GRCm38)	splice site	probably null
R5434:Ryr3	UTSW	2	112,794,469 (GRCm38)	missense	probably damaging	1.00
R5454:Ryr3	UTSW	2	112,730,302 (GRCm38)	splice site	probably null
R5501:Ryr3	UTSW	2	112,662,504 (GRCm38)	missense	possibly damaging	0.80
R5560:Ryr3	UTSW	2	112,754,877 (GRCm38)	missense	probably damaging	1.00
R5580:Ryr3	UTSW	2	112,841,948 (GRCm38)	missense	probably damaging	1.00
R5621:Ryr3	UTSW	2	112,900,984 (GRCm38)	nonsense	probably null
R5731:Ryr3	UTSW	2	112,641,572 (GRCm38)	missense	probably damaging	1.00
R5757:Ryr3	UTSW	2	112,841,975 (GRCm38)	missense	probably damaging	1.00
R5758:Ryr3	UTSW	2	112,841,975 (GRCm38)	missense	probably damaging	1.00
R5768:Ryr3	UTSW	2	112,753,097 (GRCm38)	missense	probably benign	0.05
R5783:Ryr3	UTSW	2	112,652,998 (GRCm38)	missense	probably benign	0.06
R5799:Ryr3	UTSW	2	112,686,580 (GRCm38)	missense	probably damaging	1.00
R5829:Ryr3	UTSW	2	112,859,731 (GRCm38)	missense	probably damaging	1.00
R5883:Ryr3	UTSW	2	113,030,292 (GRCm38)	intron	probably benign
R5911:Ryr3	UTSW	2	112,908,487 (GRCm38)	missense	probably damaging	1.00
R5968:Ryr3	UTSW	2	112,647,049 (GRCm38)	missense	probably benign	0.22
R5972:Ryr3	UTSW	2	112,834,064 (GRCm38)	missense	probably damaging	0.99
R5978:Ryr3	UTSW	2	112,672,269 (GRCm38)	missense	probably benign	0.00
R6084:Ryr3	UTSW	2	112,908,493 (GRCm38)	missense	probably damaging	1.00
R6117:Ryr3	UTSW	2	112,635,396 (GRCm38)	missense	probably damaging	1.00
R6126:Ryr3	UTSW	2	112,757,670 (GRCm38)	missense	probably damaging	1.00
R6128:Ryr3	UTSW	2	112,954,294 (GRCm38)	critical splice donor site	probably null
R6157:Ryr3	UTSW	2	112,841,899 (GRCm38)	missense	probably damaging	0.98
R6258:Ryr3	UTSW	2	112,660,104 (GRCm38)	missense	probably damaging	1.00
R6260:Ryr3	UTSW	2	112,660,104 (GRCm38)	missense	probably damaging	1.00
R6373:Ryr3	UTSW	2	112,656,544 (GRCm38)	missense	probably damaging	1.00
R6377:Ryr3	UTSW	2	112,632,185 (GRCm38)	missense	probably damaging	1.00
R6443:Ryr3	UTSW	2	112,675,933 (GRCm38)	missense	possibly damaging	0.88
R6478:Ryr3	UTSW	2	112,660,068 (GRCm38)	missense	probably damaging	1.00
R6512:Ryr3	UTSW	2	112,867,378 (GRCm38)	missense	possibly damaging	0.83
R6684:Ryr3	UTSW	2	112,753,088 (GRCm38)	missense	probably damaging	1.00
R6753:Ryr3	UTSW	2	112,652,610 (GRCm38)	missense	probably damaging	0.99
R6812:Ryr3	UTSW	2	112,946,906 (GRCm38)	missense	probably damaging	1.00
R6910:Ryr3	UTSW	2	112,958,175 (GRCm38)	missense	probably damaging	1.00
R6930:Ryr3	UTSW	2	112,860,354 (GRCm38)	missense	probably damaging	1.00
R6946:Ryr3	UTSW	2	112,831,200 (GRCm38)	missense	probably damaging	1.00
R6950:Ryr3	UTSW	2	112,686,825 (GRCm38)	missense	possibly damaging	0.78
R6973:Ryr3	UTSW	2	112,766,311 (GRCm38)	missense	probably damaging	0.99
R6984:Ryr3	UTSW	2	112,875,091 (GRCm38)	missense	probably damaging	1.00
R7020:Ryr3	UTSW	2	112,753,078 (GRCm38)	missense	probably benign	0.00
R7037:Ryr3	UTSW	2	112,949,130 (GRCm38)	nonsense	probably null
R7166:Ryr3	UTSW	2	112,875,028 (GRCm38)	missense	probably damaging	1.00
R7172:Ryr3	UTSW	2	112,661,657 (GRCm38)	missense	probably damaging	1.00
R7177:Ryr3	UTSW	2	112,900,843 (GRCm38)	missense	probably damaging	1.00
R7188:Ryr3	UTSW	2	113,028,644 (GRCm38)	missense	probably damaging	1.00
R7202:Ryr3	UTSW	2	112,766,319 (GRCm38)	missense	probably damaging	1.00
R7228:Ryr3	UTSW	2	112,861,852 (GRCm38)	missense	probably damaging	1.00
R7256:Ryr3	UTSW	2	112,672,246 (GRCm38)	nonsense	probably null
R7293:Ryr3	UTSW	2	112,902,603 (GRCm38)	missense	probably benign	0.13
R7331:Ryr3	UTSW	2	112,763,665 (GRCm38)	missense	possibly damaging	0.80
R7380:Ryr3	UTSW	2	112,640,157 (GRCm38)	missense	probably damaging	1.00
R7391:Ryr3	UTSW	2	112,780,977 (GRCm38)	critical splice donor site	probably null
R7455:Ryr3	UTSW	2	112,728,866 (GRCm38)	missense	probably damaging	0.99
R7481:Ryr3	UTSW	2	112,678,094 (GRCm38)	missense	possibly damaging	0.95
R7481:Ryr3	UTSW	2	112,678,093 (GRCm38)	missense	probably benign	0.16
R7497:Ryr3	UTSW	2	112,730,473 (GRCm38)	missense	probably benign	0.06
R7502:Ryr3	UTSW	2	112,712,361 (GRCm38)	missense	probably benign	0.00
R7505:Ryr3	UTSW	2	112,712,429 (GRCm38)	missense	probably damaging	0.99
R7581:Ryr3	UTSW	2	112,753,027 (GRCm38)	missense	probably damaging	0.99
R7606:Ryr3	UTSW	2	112,645,245 (GRCm38)	nonsense	probably null
R7677:Ryr3	UTSW	2	112,833,900 (GRCm38)	missense	probably benign
R7703:Ryr3	UTSW	2	112,859,765 (GRCm38)	missense	probably damaging	1.00
R7713:Ryr3	UTSW	2	112,635,346 (GRCm38)	missense	probably benign	0.12
R7784:Ryr3	UTSW	2	112,775,695 (GRCm38)	missense	probably damaging	1.00
R7831:Ryr3	UTSW	2	112,926,838 (GRCm38)	missense	possibly damaging	0.92
R7851:Ryr3	UTSW	2	112,678,517 (GRCm38)	missense	probably benign	0.05
R7873:Ryr3	UTSW	2	112,730,428 (GRCm38)	missense	probably benign	0.28
R7890:Ryr3	UTSW	2	112,926,912 (GRCm38)	missense	probably damaging	1.00
R7899:Ryr3	UTSW	2	112,646,950 (GRCm38)	missense	possibly damaging	0.86
R7904:Ryr3	UTSW	2	112,781,024 (GRCm38)	missense	probably damaging	1.00
R7929:Ryr3	UTSW	2	112,834,188 (GRCm38)	missense	probably benign	0.00
R7982:Ryr3	UTSW	2	112,669,249 (GRCm38)	small deletion	probably benign
R8018:Ryr3	UTSW	2	112,678,432 (GRCm38)	missense	probably damaging	1.00
R8043:Ryr3	UTSW	2	112,875,077 (GRCm38)	missense	probably damaging	1.00
R8043:Ryr3	UTSW	2	112,775,664 (GRCm38)	missense	probably damaging	1.00
R8095:Ryr3	UTSW	2	112,668,043 (GRCm38)	critical splice donor site	probably null
R8097:Ryr3	UTSW	2	112,670,270 (GRCm38)	splice site	probably null
R8181:Ryr3	UTSW	2	112,778,243 (GRCm38)	missense	probably damaging	0.98
R8276:Ryr3	UTSW	2	112,640,617 (GRCm38)	missense	probably damaging	1.00
R8329:Ryr3	UTSW	2	112,662,510 (GRCm38)	missense	possibly damaging	0.94
R8345:Ryr3	UTSW	2	112,652,925 (GRCm38)	missense	probably benign	0.01
R8361:Ryr3	UTSW	2	112,653,130 (GRCm38)	missense	probably damaging	0.98
R8421:Ryr3	UTSW	2	112,996,584 (GRCm38)	missense	probably benign	0.00
R8424:Ryr3	UTSW	2	112,841,894 (GRCm38)	missense	possibly damaging	0.91
R8471:Ryr3	UTSW	2	112,653,780 (GRCm38)	missense	probably damaging	1.00
R8505:Ryr3	UTSW	2	112,675,870 (GRCm38)	missense	probably damaging	0.98
R8535:Ryr3	UTSW	2	112,949,088 (GRCm38)	critical splice donor site	probably null
R8540:Ryr3	UTSW	2	112,800,022 (GRCm38)	missense	probably damaging	1.00
R8722:Ryr3	UTSW	2	112,772,771 (GRCm38)	missense	probably benign	0.12
R8818:Ryr3	UTSW	2	112,831,096 (GRCm38)	missense	probably damaging	1.00
R8819:Ryr3	UTSW	2	112,859,724 (GRCm38)	missense	probably benign	0.01
R8819:Ryr3	UTSW	2	112,635,792 (GRCm38)	missense	probably damaging	1.00
R8820:Ryr3	UTSW	2	112,859,724 (GRCm38)	missense	probably benign	0.01
R8820:Ryr3	UTSW	2	112,635,792 (GRCm38)	missense	probably damaging	1.00
R8852:Ryr3	UTSW	2	112,794,499 (GRCm38)	missense	probably damaging	1.00
R8859:Ryr3	UTSW	2	112,653,219 (GRCm38)	missense	probably damaging	0.98
R8896:Ryr3	UTSW	2	112,753,050 (GRCm38)	nonsense	probably null
R8916:Ryr3	UTSW	2	112,778,290 (GRCm38)	missense	probably damaging	1.00
R8935:Ryr3	UTSW	2	112,678,057 (GRCm38)	missense	probably benign	0.33
R8943:Ryr3	UTSW	2	112,635,324 (GRCm38)	missense	probably damaging	1.00
R8963:Ryr3	UTSW	2	112,836,670 (GRCm38)	critical splice donor site	probably null
R8974:Ryr3	UTSW	2	112,912,279 (GRCm38)	missense	possibly damaging	0.74
R9008:Ryr3	UTSW	2	112,635,403 (GRCm38)	missense	probably damaging	0.98
R9040:Ryr3	UTSW	2	112,954,386 (GRCm38)	missense	probably damaging	1.00
R9041:Ryr3	UTSW	2	112,957,201 (GRCm38)	missense	probably damaging	0.97
R9102:Ryr3	UTSW	2	112,678,561 (GRCm38)	splice site	probably benign
R9167:Ryr3	UTSW	2	112,834,053 (GRCm38)	missense	probably damaging	1.00
R9180:Ryr3	UTSW	2	112,661,636 (GRCm38)	missense	probably damaging	0.99
R9219:Ryr3	UTSW	2	112,912,239 (GRCm38)	missense	possibly damaging	0.62
R9258:Ryr3	UTSW	2	112,653,019 (GRCm38)	missense	probably damaging	0.99
R9300:Ryr3	UTSW	2	112,860,350 (GRCm38)	missense	probably benign
R9320:Ryr3	UTSW	2	112,779,991 (GRCm38)	missense	probably damaging	1.00
R9325:Ryr3	UTSW	2	112,649,295 (GRCm38)	missense	probably damaging	0.96
R9405:Ryr3	UTSW	2	112,834,267 (GRCm38)	missense	probably damaging	1.00
R9414:Ryr3	UTSW	2	112,670,666 (GRCm38)	missense	possibly damaging	0.81
R9489:Ryr3	UTSW	2	112,661,621 (GRCm38)	missense	probably damaging	1.00
R9522:Ryr3	UTSW	2	112,730,414 (GRCm38)	missense	probably benign	0.34
R9526:Ryr3	UTSW	2	112,833,925 (GRCm38)	missense	probably benign
R9529:Ryr3	UTSW	2	112,635,315 (GRCm38)	missense	possibly damaging	0.70
R9605:Ryr3	UTSW	2	112,661,621 (GRCm38)	missense	probably damaging	1.00
R9652:Ryr3	UTSW	2	112,804,702 (GRCm38)	missense	possibly damaging	0.66
R9660:Ryr3	UTSW	2	112,833,729 (GRCm38)	missense	probably benign
R9670:Ryr3	UTSW	2	112,730,500 (GRCm38)	missense	probably benign	0.28
R9673:Ryr3	UTSW	2	112,656,538 (GRCm38)	missense	possibly damaging	0.93
R9710:Ryr3	UTSW	2	112,803,189 (GRCm38)	missense	probably damaging	0.99
R9741:Ryr3	UTSW	2	112,646,926 (GRCm38)	missense	probably benign	0.00
R9772:Ryr3	UTSW	2	112,826,703 (GRCm38)	missense	probably damaging	0.96
RF010:Ryr3	UTSW	2	112,775,670 (GRCm38)	missense	probably damaging	0.97
RF040:Ryr3	UTSW	2	112,910,524 (GRCm38)	critical splice acceptor site	probably benign
RF044:Ryr3	UTSW	2	112,910,524 (GRCm38)	critical splice acceptor site	probably benign
X0057:Ryr3	UTSW	2	112,640,159 (GRCm38)	missense	probably damaging	1.00
X0064:Ryr3	UTSW	2	112,912,302 (GRCm38)	missense	probably benign	0.26
Z1088:Ryr3	UTSW	2	112,900,916 (GRCm38)	missense	probably damaging	1.00
Z1176:Ryr3	UTSW	2	112,728,924 (GRCm38)	missense	probably benign	0.01
Z1176:Ryr3	UTSW	2	112,712,374 (GRCm38)	missense	probably damaging	1.00
Z1176:Ryr3	UTSW	2	112,675,920 (GRCm38)	missense	probably benign	0.05

Predicted Primers

PCR Primer
(F):5'- CCAGAGTCACTCCTGTCTAACTG -3'
(R):5'- TTCTGAAATCCTAGCTAGCTTGG -3'

Sequencing Primer
(F):5'- GTAAACCCTGTATAACCATTAGACCC -3'
(R):5'- CCTAGCTAGCTTGGAGACATG -3'

Posted On

2019-10-07