Mutagenetix > Incidental Mutation

Incidental Mutation 'R7466:Mgam'

578768

Institutional Source

Beutler Lab

Gene Symbol

Mgam

Ensembl Gene

ENSMUSG00000068587

Gene Name

maltase-glucoamylase

Synonyms

6030407P20Rik

MMRRC Submission

045540-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.192) question?

Stock #

R7466 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

40628831-40769123 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 40744789 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Asparagine to Serine at position 347 (N347S)

Ref Sequence

ENSEMBL: ENSMUSP00000144627 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000071535] [ENSMUST00000201148] [ENSMUST00000202779] [ENSMUST00000202966]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000071535

SMART Domains

Protein: ENSMUSP00000071466
Gene: ENSMUSG00000068587

Domain	Start	End	E-Value	Type
transmembrane domain	12	34	N/A	INTRINSIC
low complexity region	47	59	N/A	INTRINSIC
PD	63	111	1.81e-8	SMART
Pfam:NtCtMGAM_N	124	233	6.2e-36	PFAM
Pfam:Glyco_hydro_31	323	795	3.4e-145	PFAM
PD	924	977	4.52e-9	SMART
Pfam:NtCtMGAM_N	988	1101	1.5e-30	PFAM
Blast:ANK	1141	1171	1e-7	BLAST
Pfam:Glyco_hydro_31	1189	1691	2e-139	PFAM
low complexity region	1776	1791	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000201148

SMART Domains

Protein: ENSMUSP00000143946
Gene: ENSMUSG00000068587

Domain	Start	End	E-Value	Type
transmembrane domain	12	34	N/A	INTRINSIC
low complexity region	47	59	N/A	INTRINSIC
PD	63	111	1.81e-8	SMART
Pfam:NtCtMGAM_N	124	233	6.2e-36	PFAM
Pfam:Glyco_hydro_31	323	795	3.4e-145	PFAM
PD	924	977	4.52e-9	SMART
Pfam:NtCtMGAM_N	988	1101	1.5e-30	PFAM
Blast:ANK	1141	1171	1e-7	BLAST
Pfam:Glyco_hydro_31	1189	1691	2e-139	PFAM
low complexity region	1776	1791	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000202779
AA Change: N347S

PolyPhen 2 Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)

SMART Domains

Protein: ENSMUSP00000144627
Gene: ENSMUSG00000068587
AA Change: N347S

Domain	Start	End	E-Value	Type
Pfam:Glyco_hydro_31	2	170	1.4e-53	PFAM
PD	297	350	1.4e-14	SMART
Pfam:NtCtMGAM_N	361	474	1.5e-26	PFAM
Blast:ANK	514	544	7e-8	BLAST
Pfam:Glyco_hydro_31	562	1064	2.2e-137	PFAM
low complexity region	1149	1164	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000202966
AA Change: N228S

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000144680
Gene: ENSMUSG00000068587
AA Change: N228S

Domain	Start	End	E-Value	Type
internal_repeat_1	2	88	2.6e-19	PROSPERO
PD	178	231	1.4e-14	SMART
Pfam:NtCtMGAM_N	242	355	1.1e-26	PFAM
Blast:ANK	395	425	6e-8	BLAST
Pfam:Glyco_hydro_31	443	945	1.3e-137	PFAM

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.8%
20x: 99.2%

Validation Efficiency

99% (83/84)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes maltase-glucoamylase, which is a brush border membrane enzyme that plays a role in the final steps of digestion of starch. The protein has two catalytic sites identical to those of sucrase-isomaltase, but the proteins are only 59% homologous. Both are members of glycosyl hydrolase family 31, which has a variety of substrate specificities. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a null allele display abnormalities in starch digestion and prandial glucose homeostasis. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 83 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
AI182371	T	A	2: 35,088,741 (GRCm38)	K203*	probably null	Het
Akr1c13	T	C	13: 4,192,437 (GRCm38)		probably benign	Het
Amer3	A	G	1: 34,587,993 (GRCm38)	S438G	probably damaging	Het
Aqp9	T	A	9: 71,163,261 (GRCm38)		probably null	Het
Art4	G	T	6: 136,854,850 (GRCm38)	H98N	probably damaging	Het
Bdh1	T	C	16: 31,447,604 (GRCm38)	S70P	probably benign	Het
Ccdc61	A	C	7: 18,891,105 (GRCm38)	Y503D	probably damaging	Het
Cd163l1	T	C	7: 140,220,706 (GRCm38)		probably null	Het
Cd180	A	T	13: 102,704,995 (GRCm38)	N183I	probably damaging	Het
Cd200r2	C	T	16: 44,909,174 (GRCm38)	A64V	probably damaging	Het
Ceacam9	A	C	7: 16,723,855 (GRCm38)	K98Q	probably benign	Het
Cep44	AACGC	A	8: 56,540,983 (GRCm38)		probably null	Het
Cfap77	G	T	2: 28,955,613 (GRCm38)	D247E	probably benign	Het
Cftr	T	C	6: 18,227,973 (GRCm38)	M388T	probably benign	Het
Chrnb1	G	A	11: 69,784,650 (GRCm38)	H493Y	probably damaging	Het
Ckap2	A	C	8: 22,177,386 (GRCm38)	M153R	probably benign	Het
Cnot6l	A	G	5: 96,131,128 (GRCm38)	V77A	probably benign	Het
Col12a1	C	T	9: 79,655,407 (GRCm38)	E1798K	possibly damaging	Het
Cth	T	A	3: 157,924,885 (GRCm38)	D49V	probably benign	Het
Ctnnb1	T	C	9: 120,955,416 (GRCm38)	S425P	probably damaging	Het
Ctnnd1	T	C	2: 84,610,785 (GRCm38)	N690S	probably benign	Het
Cyhr1	C	T	15: 76,648,186 (GRCm38)	D241N	probably benign	Het
Dennd4c	A	G	4: 86,774,331 (GRCm38)	D26G	probably damaging	Het
Dlg5	G	A	14: 24,245,212 (GRCm38)	P80L	probably damaging	Het
Eef2k	A	G	7: 120,903,484 (GRCm38)		probably null	Het
Ephb2	C	T	4: 136,659,065 (GRCm38)	R791H	probably damaging	Het
Erh	T	C	12: 80,640,983 (GRCm38)	Y22C	probably benign	Het
F5	C	T	1: 164,193,328 (GRCm38)	T1124I	possibly damaging	Het
Fam220a	T	A	5: 143,563,471 (GRCm38)	C213S	possibly damaging	Het
Fat2	G	T	11: 55,310,432 (GRCm38)	N605K	probably damaging	Het
Ganab	C	A	19: 8,914,569 (GRCm38)	S780*	probably null	Het
Gbgt1	C	T	2: 28,502,207 (GRCm38)	P67S	probably damaging	Het
Gm17190	G	T	13: 96,082,779 (GRCm38)	G208*	probably null	Het
Grhl2	A	G	15: 37,291,616 (GRCm38)	Y316C	probably damaging	Het
H2-T10	T	C	17: 36,120,849 (GRCm38)	T38A	probably benign	Het
Ins1	A	G	19: 52,264,420 (GRCm38)		probably benign	Het
Ippk	T	C	13: 49,432,467 (GRCm38)		probably null	Het
Klc4	T	A	17: 46,639,910 (GRCm38)	I258F	probably benign	Het
Manba	C	A	3: 135,542,393 (GRCm38)	L348I	probably benign	Het
Myo18b	T	C	5: 112,723,892 (GRCm38)	T2108A	probably benign	Het
Naip5	A	T	13: 100,221,986 (GRCm38)	L914*	probably null	Het
Nsa2	C	T	13: 97,131,220 (GRCm38)	A242T	probably benign	Het
Nsd2	G	A	5: 33,882,147 (GRCm38)	W834*	probably null	Het
Olfr1134	T	C	2: 87,656,396 (GRCm38)	N175S	possibly damaging	Het
Olfr1419	T	A	19: 11,870,316 (GRCm38)	D300V	possibly damaging	Het
Olfr285	T	C	15: 98,313,380 (GRCm38)	M57V	probably damaging	Het
Olfr469	A	T	7: 107,822,922 (GRCm38)	C182*	probably null	Het
Pam	A	T	1: 97,842,247 (GRCm38)	D599E	probably damaging	Het
Phf20l1	A	G	15: 66,636,884 (GRCm38)	K864R	probably damaging	Het
Plcl2	A	G	17: 50,608,468 (GRCm38)	D835G	probably damaging	Het
Ppm1m	C	A	9: 106,196,157 (GRCm38)	A329S	probably damaging	Het
Prep	T	C	10: 45,150,438 (GRCm38)	V486A	probably benign	Het
Prkcb	A	T	7: 122,516,844 (GRCm38)	N182I	probably damaging	Het
Prkcz	A	G	4: 155,271,602 (GRCm38)	F355S	probably damaging	Het
Psg20	C	T	7: 18,684,467 (GRCm38)	S125N	probably benign	Het
Psmd12	A	G	11: 107,492,057 (GRCm38)	D234G	probably benign	Het
Pvrig	A	T	5: 138,342,008 (GRCm38)	M14L	probably benign	Het
Rabgap1l	C	T	1: 160,226,484 (GRCm38)		probably null	Het
Rfc1	A	T	5: 65,275,426 (GRCm38)	C764S	probably damaging	Het
Ryr3	T	C	2: 112,926,957 (GRCm38)	D351G	probably benign	Het
Serpinb9g	T	C	13: 33,495,167 (GRCm38)	F340S	probably benign	Het
Sirpb1c	C	A	3: 15,832,266 (GRCm38)	L315F	probably damaging	Het
Slc24a1	C	G	9: 64,928,404 (GRCm38)	E814Q	unknown	Het
Slc26a11	A	T	11: 119,374,502 (GRCm38)	Q355L	probably damaging	Het
Sp100	C	T	1: 85,707,239 (GRCm38)	L483F	possibly damaging	Het
St5	A	G	7: 109,525,346 (GRCm38)	L1096P	probably damaging	Het
Ston1	T	A	17: 88,635,901 (GRCm38)	M245K	probably benign	Het
Swap70	T	A	7: 110,274,772 (GRCm38)	D442E	probably benign	Het
Syne2	T	A	12: 76,046,186 (GRCm38)	V450D	possibly damaging	Het
Tbck	T	A	3: 132,752,563 (GRCm38)	N651K	probably damaging	Het
Timd4	A	T	11: 46,817,758 (GRCm38)	T204S	probably benign	Het
Tmem102	A	G	11: 69,804,885 (GRCm38)	L87P	probably damaging	Het
Tmem55a	T	A	4: 14,912,477 (GRCm38)	Y195*	probably null	Het
Tmprss11e	T	A	5: 86,709,480 (GRCm38)	T325S	probably benign	Het
Trpm1	G	A	7: 64,240,582 (GRCm38)	V978M	probably damaging	Het
Wdr12	A	T	1: 60,094,511 (GRCm38)	D19E	probably benign	Het
Wdr35	G	A	12: 9,005,773 (GRCm38)	V482I	probably benign	Het
Wdr63	T	C	3: 146,055,618 (GRCm38)	D661G	probably benign	Het
Zer1	T	C	2: 30,101,484 (GRCm38)		probably null	Het
Zfp503	T	C	14: 21,986,011 (GRCm38)	D279G	probably benign	Het
Zfp870	A	T	17: 32,883,762 (GRCm38)	C198S	possibly damaging	Het
Zfyve26	C	T	12: 79,287,807 (GRCm38)	E146K	probably benign	Het
Zkscan6	T	C	11: 65,828,531 (GRCm38)	V459A	probably damaging	Het

Other mutations in Mgam

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01024:Mgam	APN	6	40,643,010 (GRCm38)	missense	probably benign
IGL01065:Mgam	APN	6	40,662,710 (GRCm38)	critical splice donor site	probably null
IGL01402:Mgam	APN	6	40,644,945 (GRCm38)	missense	probably benign	0.01
IGL01404:Mgam	APN	6	40,644,945 (GRCm38)	missense	probably benign	0.01
IGL01413:Mgam	APN	6	40,661,277 (GRCm38)	missense	probably damaging	1.00
IGL01546:Mgam	APN	6	40,654,693 (GRCm38)	missense	probably damaging	0.98
IGL01596:Mgam	APN	6	40,658,270 (GRCm38)	missense	probably damaging	1.00
IGL02133:Mgam	APN	6	40,643,076 (GRCm38)	missense	probably damaging	0.98
IGL02734:Mgam	APN	6	40,662,694 (GRCm38)	missense	probably damaging	1.00
BB002:Mgam	UTSW	6	40,759,051 (GRCm38)	missense	probably damaging	0.99
BB012:Mgam	UTSW	6	40,759,051 (GRCm38)	missense	probably damaging	0.99
R0012:Mgam	UTSW	6	40,765,256 (GRCm38)	splice site	probably null
R0116:Mgam	UTSW	6	40,658,987 (GRCm38)	missense	probably damaging	1.00
R0310:Mgam	UTSW	6	40,761,035 (GRCm38)	splice site	probably benign
R0452:Mgam	UTSW	6	40,759,090 (GRCm38)	missense	probably damaging	1.00
R0497:Mgam	UTSW	6	40,664,892 (GRCm38)	missense	probably damaging	1.00
R0699:Mgam	UTSW	6	40,643,019 (GRCm38)	missense	possibly damaging	0.84
R0738:Mgam	UTSW	6	40,754,935 (GRCm38)	missense	probably benign	0.01
R1033:Mgam	UTSW	6	40,680,624 (GRCm38)	missense	probably benign	0.07
R1403:Mgam	UTSW	6	40,666,881 (GRCm38)	missense	possibly damaging	0.93
R1403:Mgam	UTSW	6	40,666,881 (GRCm38)	missense	possibly damaging	0.93
R1430:Mgam	UTSW	6	40,756,371 (GRCm38)	missense	probably benign	0.08
R1432:Mgam	UTSW	6	40,756,367 (GRCm38)	missense	probably damaging	1.00
R1443:Mgam	UTSW	6	40,759,780 (GRCm38)	nonsense	probably null
R1470:Mgam	UTSW	6	40,759,128 (GRCm38)	missense	probably damaging	1.00
R1470:Mgam	UTSW	6	40,759,128 (GRCm38)	missense	probably damaging	1.00
R1519:Mgam	UTSW	6	40,661,683 (GRCm38)	missense	probably benign	0.45
R1654:Mgam	UTSW	6	40,757,487 (GRCm38)	missense	probably damaging	1.00
R1667:Mgam	UTSW	6	40,677,044 (GRCm38)	missense	possibly damaging	0.62
R1730:Mgam	UTSW	6	40,664,860 (GRCm38)	missense	possibly damaging	0.92
R1781:Mgam	UTSW	6	40,669,863 (GRCm38)	missense	probably damaging	1.00
R1783:Mgam	UTSW	6	40,664,860 (GRCm38)	missense	possibly damaging	0.92
R1829:Mgam	UTSW	6	40,666,892 (GRCm38)	missense	probably damaging	1.00
R1833:Mgam	UTSW	6	40,654,718 (GRCm38)	critical splice donor site	probably null
R1872:Mgam	UTSW	6	40,661,300 (GRCm38)	nonsense	probably null
R1912:Mgam	UTSW	6	40,764,185 (GRCm38)	nonsense	probably null
R1977:Mgam	UTSW	6	40,664,880 (GRCm38)	missense	probably benign	0.01
R2048:Mgam	UTSW	6	40,656,429 (GRCm38)	missense	possibly damaging	0.80
R2086:Mgam	UTSW	6	40,761,028 (GRCm38)	splice site	probably null
R2138:Mgam	UTSW	6	40,756,450 (GRCm38)	missense	probably damaging	1.00
R2224:Mgam	UTSW	6	40,764,274 (GRCm38)	splice site	probably null
R2408:Mgam	UTSW	6	40,686,522 (GRCm38)	missense	probably damaging	1.00
R2508:Mgam	UTSW	6	40,759,783 (GRCm38)	missense	probably damaging	1.00
R2842:Mgam	UTSW	6	40,661,345 (GRCm38)	missense	probably benign	0.01
R2847:Mgam	UTSW	6	40,652,715 (GRCm38)	missense	possibly damaging	0.67
R2848:Mgam	UTSW	6	40,652,715 (GRCm38)	missense	possibly damaging	0.67
R2965:Mgam	UTSW	6	40,768,220 (GRCm38)	missense	possibly damaging	0.46
R2966:Mgam	UTSW	6	40,768,220 (GRCm38)	missense	possibly damaging	0.46
R3035:Mgam	UTSW	6	40,663,530 (GRCm38)	missense	probably benign
R3895:Mgam	UTSW	6	40,759,120 (GRCm38)	missense	probably damaging	1.00
R4027:Mgam	UTSW	6	40,754,902 (GRCm38)	missense	probably damaging	1.00
R4030:Mgam	UTSW	6	40,754,902 (GRCm38)	missense	probably damaging	1.00
R4302:Mgam	UTSW	6	40,763,085 (GRCm38)	missense	probably benign	0.02
R4707:Mgam	UTSW	6	40,714,632 (GRCm38)	splice site	probably null
R4826:Mgam	UTSW	6	40,680,648 (GRCm38)	missense	possibly damaging	0.52
R4898:Mgam	UTSW	6	40,643,054 (GRCm38)	missense	probably benign
R5438:Mgam	UTSW	6	40,684,521 (GRCm38)	missense	probably damaging	1.00
R5492:Mgam	UTSW	6	40,756,363 (GRCm38)	missense	probably damaging	1.00
R5770:Mgam	UTSW	6	40,669,804 (GRCm38)	missense	probably benign	0.01
R5839:Mgam	UTSW	6	40,740,064 (GRCm38)	missense	possibly damaging	0.90
R5845:Mgam	UTSW	6	40,675,323 (GRCm38)	missense	possibly damaging	0.78
R5847:Mgam	UTSW	6	40,684,055 (GRCm38)	missense	probably benign	0.42
R5891:Mgam	UTSW	6	40,744,348 (GRCm38)	missense	probably benign
R6158:Mgam	UTSW	6	40,757,714 (GRCm38)	missense	probably damaging	1.00
R6193:Mgam	UTSW	6	40,747,920 (GRCm38)	nonsense	probably null
R6423:Mgam	UTSW	6	40,677,045 (GRCm38)	missense	possibly damaging	0.84
R6706:Mgam	UTSW	6	40,744,786 (GRCm38)	missense	probably benign	0.00
R6813:Mgam	UTSW	6	40,750,165 (GRCm38)	missense	probably damaging	0.99
R6863:Mgam	UTSW	6	40,729,009 (GRCm38)	missense	probably benign	0.00
R6906:Mgam	UTSW	6	40,747,919 (GRCm38)	missense	probably damaging	1.00
R7091:Mgam	UTSW	6	40,768,276 (GRCm38)	missense	possibly damaging	0.95
R7099:Mgam	UTSW	6	40,661,716 (GRCm38)	missense	probably benign	0.09
R7282:Mgam	UTSW	6	40,763,111 (GRCm38)	missense	probably benign
R7282:Mgam	UTSW	6	40,656,512 (GRCm38)	missense	possibly damaging	0.71
R7354:Mgam	UTSW	6	40,744,798 (GRCm38)	missense	probably damaging	1.00
R7374:Mgam	UTSW	6	40,757,439 (GRCm38)	missense	possibly damaging	0.89
R7399:Mgam	UTSW	6	40,666,854 (GRCm38)	missense	probably damaging	0.99
R7406:Mgam	UTSW	6	40,663,525 (GRCm38)	missense	probably benign	0.13
R7446:Mgam	UTSW	6	40,746,332 (GRCm38)	missense	probably damaging	1.00
R7525:Mgam	UTSW	6	40,766,020 (GRCm38)	missense	probably benign	0.01
R7530:Mgam	UTSW	6	40,709,218 (GRCm38)	splice site	probably null
R7570:Mgam	UTSW	6	40,746,433 (GRCm38)	missense	probably benign	0.16
R7669:Mgam	UTSW	6	40,659,010 (GRCm38)	missense	probably benign	0.00
R7679:Mgam	UTSW	6	40,643,046 (GRCm38)	missense	probably damaging	0.98
R7746:Mgam	UTSW	6	40,668,193 (GRCm38)	missense	probably damaging	0.99
R7859:Mgam	UTSW	6	40,740,179 (GRCm38)	missense	possibly damaging	0.75
R7925:Mgam	UTSW	6	40,759,051 (GRCm38)	missense	probably damaging	0.99
R8206:Mgam	UTSW	6	40,680,235 (GRCm38)	missense	probably benign	0.00
R8244:Mgam	UTSW	6	40,750,586 (GRCm38)	missense	probably damaging	1.00
R8309:Mgam	UTSW	6	40,745,177 (GRCm38)	missense	possibly damaging	0.88
R8472:Mgam	UTSW	6	40,694,526 (GRCm38)	splice site	probably null
R8758:Mgam	UTSW	6	40,729,043 (GRCm38)	missense	probably benign	0.41
R8777:Mgam	UTSW	6	40,655,251 (GRCm38)	missense	probably damaging	0.97
R8777-TAIL:Mgam	UTSW	6	40,655,251 (GRCm38)	missense	probably damaging	0.97
R8783:Mgam	UTSW	6	40,656,489 (GRCm38)	missense	probably damaging	0.99
R8939:Mgam	UTSW	6	40,763,203 (GRCm38)	critical splice donor site	probably null
R8968:Mgam	UTSW	6	40,757,811 (GRCm38)	critical splice acceptor site	probably null
R8987:Mgam	UTSW	6	40,729,636 (GRCm38)	missense	probably damaging	1.00
R9055:Mgam	UTSW	6	40,714,729 (GRCm38)	intron	probably benign
R9171:Mgam	UTSW	6	40,768,212 (GRCm38)	missense	possibly damaging	0.76
R9252:Mgam	UTSW	6	40,729,643 (GRCm38)	missense	probably damaging	0.99
R9258:Mgam	UTSW	6	40,680,187 (GRCm38)	missense	probably benign
R9262:Mgam	UTSW	6	40,746,488 (GRCm38)	critical splice donor site	probably null
R9287:Mgam	UTSW	6	40,728,971 (GRCm38)	intron	probably benign
R9521:Mgam	UTSW	6	40,745,184 (GRCm38)	missense	probably damaging	1.00
R9589:Mgam	UTSW	6	40,750,585 (GRCm38)	missense	probably damaging	1.00
R9658:Mgam	UTSW	6	40,744,377 (GRCm38)	missense	possibly damaging	0.93
R9784:Mgam	UTSW	6	40,759,090 (GRCm38)	missense	probably damaging	1.00
RF011:Mgam	UTSW	6	40,757,436 (GRCm38)	missense	probably damaging	1.00
RF020:Mgam	UTSW	6	40,685,309 (GRCm38)	missense	probably damaging	1.00
RF023:Mgam	UTSW	6	40,680,708 (GRCm38)	missense	probably benign
X0021:Mgam	UTSW	6	40,659,047 (GRCm38)	missense	probably damaging	1.00
Z1088:Mgam	UTSW	6	40,643,060 (GRCm38)	missense	probably benign	0.01
Z1176:Mgam	UTSW	6	40,729,066 (GRCm38)	missense	probably damaging	1.00
Z1176:Mgam	UTSW	6	40,677,644 (GRCm38)	critical splice donor site	probably null
Z1177:Mgam	UTSW	6	40,740,071 (GRCm38)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- GCATAACTGGGCATAGGACTG -3'
(R):5'- AGGTTCTGTCCACACCTGGTAG -3'

Sequencing Primer
(F):5'- GTACATTTCTTGAAGAGTGCGCAC -3'
(R):5'- TGTCCACACCTGGTAGCACAC -3'

Posted On

2019-10-07