Incidental Mutation 'R7470:Thada'
| ID |
579156 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Thada
|
| Ensembl Gene |
ENSMUSG00000024251 |
| Gene Name |
thyroid adenoma associated |
| Synonyms |
|
| MMRRC Submission |
045544-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7470 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
17 |
| Chromosomal Location |
84497504-84773633 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 84533469 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Aspartic acid
at position 1661
(N1661D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000041701
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000047524]
|
| AlphaFold |
A8C756 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000047524
AA Change: N1661D
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000041701
Gene: ENSMUSG00000024251
AA Change: N1661D
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1gw5a_
|
457 |
926 |
3e-6 |
SMART |
|
Pfam:DUF2428
|
938 |
1239 |
1.6e-93 |
PFAM |
|
SCOP:d1gw5a_
|
1343 |
1802 |
7e-6 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 98.9%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene is the target of 2p21 choromosomal aberrations in benign thyroid adenomas. Single nucleotide polymorphisms (SNPs) in this gene may be associated with type 2 diabetes and polycystic ovary syndrome. The encoded protein is likely involved in the death receptor pathway and apoptosis. [provided by RefSeq, Sep 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 84 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930563M21Rik |
A |
T |
9: 55,898,622 (GRCm39) |
V238E |
possibly damaging |
Het |
| Actn3 |
G |
A |
19: 4,917,842 (GRCm39) |
S375L |
possibly damaging |
Het |
| Adgrg6 |
T |
C |
10: 14,319,810 (GRCm39) |
T476A |
probably benign |
Het |
| Afm |
T |
A |
5: 90,679,486 (GRCm39) |
S327T |
probably damaging |
Het |
| Apol7e |
T |
A |
15: 77,602,143 (GRCm39) |
M247K |
probably benign |
Het |
| Aqp12 |
T |
A |
1: 92,936,385 (GRCm39) |
L237Q |
probably damaging |
Het |
| Arhgef12 |
A |
T |
9: 42,951,848 (GRCm39) |
S63T |
probably damaging |
Het |
| Axdnd1 |
T |
A |
1: 156,204,086 (GRCm39) |
E393V |
|
Het |
| Cacna1g |
T |
A |
11: 94,352,765 (GRCm39) |
D365V |
possibly damaging |
Het |
| Ccdc3 |
T |
A |
2: 5,143,115 (GRCm39) |
V124E |
possibly damaging |
Het |
| Ccr7 |
C |
T |
11: 99,036,383 (GRCm39) |
V180M |
possibly damaging |
Het |
| Cd47 |
T |
A |
16: 49,704,585 (GRCm39) |
I119K |
|
Het |
| Cenpe |
A |
T |
3: 134,947,916 (GRCm39) |
L1158F |
probably damaging |
Het |
| Cfi |
A |
G |
3: 129,648,736 (GRCm39) |
R207G |
probably benign |
Het |
| Cyp2j6 |
T |
C |
4: 96,423,708 (GRCm39) |
Y220C |
probably benign |
Het |
| Ddhd2 |
A |
G |
8: 26,225,087 (GRCm39) |
F577L |
probably benign |
Het |
| Dhx40 |
T |
C |
11: 86,667,528 (GRCm39) |
E537G |
probably damaging |
Het |
| Disp3 |
A |
T |
4: 148,345,527 (GRCm39) |
C438S |
possibly damaging |
Het |
| Dock3 |
A |
G |
9: 106,882,644 (GRCm39) |
S380P |
probably damaging |
Het |
| Ehmt2 |
A |
G |
17: 35,118,372 (GRCm39) |
E106G |
possibly damaging |
Het |
| Fmnl2 |
A |
T |
2: 52,932,377 (GRCm39) |
I119F |
probably damaging |
Het |
| Gm11554 |
A |
C |
11: 99,695,190 (GRCm39) |
S8A |
unknown |
Het |
| Grm7 |
A |
G |
6: 111,478,476 (GRCm39) |
I54V |
|
Het |
| Hbs1l |
T |
C |
10: 21,234,683 (GRCm39) |
F579L |
possibly damaging |
Het |
| Hgf |
C |
A |
5: 16,823,854 (GRCm39) |
Q684K |
probably benign |
Het |
| Igsf3 |
T |
C |
3: 101,358,391 (GRCm39) |
Y741H |
possibly damaging |
Het |
| Il17rb |
C |
A |
14: 29,719,990 (GRCm39) |
G304W |
probably damaging |
Het |
| Ino80c |
C |
T |
18: 24,241,895 (GRCm39) |
W163* |
probably null |
Het |
| Kcnt1 |
A |
C |
2: 25,799,845 (GRCm39) |
D997A |
probably damaging |
Het |
| Klf7 |
C |
T |
1: 64,081,472 (GRCm39) |
|
probably null |
Het |
| Lingo1 |
T |
C |
9: 56,527,908 (GRCm39) |
Y233C |
probably damaging |
Het |
| Lmo7 |
C |
A |
14: 102,138,040 (GRCm39) |
T914K |
possibly damaging |
Het |
| Mark1 |
G |
T |
1: 184,660,241 (GRCm39) |
Y138* |
probably null |
Het |
| Mcm3ap |
C |
A |
10: 76,344,231 (GRCm39) |
T1791K |
probably damaging |
Het |
| Mcts2 |
T |
C |
2: 152,529,582 (GRCm39) |
I131T |
probably benign |
Het |
| Mipep |
A |
G |
14: 61,040,344 (GRCm39) |
D288G |
probably benign |
Het |
| Ms4a8a |
T |
A |
19: 11,053,714 (GRCm39) |
N131Y |
possibly damaging |
Het |
| Nalcn |
T |
C |
14: 123,809,456 (GRCm39) |
E232G |
probably benign |
Het |
| Nat10 |
C |
T |
2: 103,565,226 (GRCm39) |
A452T |
probably benign |
Het |
| Nfatc2 |
G |
A |
2: 168,365,227 (GRCm39) |
Q596* |
probably null |
Het |
| Nudt13 |
G |
T |
14: 20,359,791 (GRCm39) |
G173W |
probably damaging |
Het |
| Or10n1 |
C |
A |
9: 39,524,998 (GRCm39) |
T45K |
probably benign |
Het |
| Or1e16 |
T |
A |
11: 73,286,714 (GRCm39) |
I45F |
probably damaging |
Het |
| Or5l14 |
A |
T |
2: 87,792,793 (GRCm39) |
C148S |
possibly damaging |
Het |
| Or8b4 |
T |
A |
9: 37,830,592 (GRCm39) |
I213N |
probably damaging |
Het |
| Otud4 |
T |
C |
8: 80,399,989 (GRCm39) |
V901A |
probably benign |
Het |
| Pah |
G |
A |
10: 87,399,286 (GRCm39) |
R155Q |
probably damaging |
Het |
| Pkd1l3 |
A |
G |
8: 110,365,008 (GRCm39) |
H1130R |
probably benign |
Het |
| Pnliprp1 |
A |
G |
19: 58,720,457 (GRCm39) |
N111S |
possibly damaging |
Het |
| Ppp1r21 |
T |
C |
17: 88,869,649 (GRCm39) |
Y401H |
probably damaging |
Het |
| Prr14 |
A |
G |
7: 127,074,997 (GRCm39) |
K466R |
probably null |
Het |
| Ralgapa2 |
A |
G |
2: 146,266,587 (GRCm39) |
L663P |
probably damaging |
Het |
| Reg3d |
A |
T |
6: 78,353,071 (GRCm39) |
C171S |
possibly damaging |
Het |
| Reln |
G |
T |
5: 22,147,739 (GRCm39) |
L2404I |
probably damaging |
Het |
| Rnasel |
A |
C |
1: 153,629,777 (GRCm39) |
I98L |
probably benign |
Het |
| Rnf216 |
T |
C |
5: 142,978,480 (GRCm39) |
D886G |
possibly damaging |
Het |
| Rp1l1 |
A |
G |
14: 64,266,015 (GRCm39) |
R534G |
probably benign |
Het |
| Selenon |
A |
C |
4: 134,267,061 (GRCm39) |
S514A |
probably benign |
Het |
| Sema3d |
T |
A |
5: 12,558,152 (GRCm39) |
I228N |
probably damaging |
Het |
| Serpinb9g |
T |
A |
13: 33,670,617 (GRCm39) |
I35N |
probably damaging |
Het |
| Siglec1 |
A |
C |
2: 130,917,744 (GRCm39) |
H1044Q |
probably benign |
Het |
| Skint5 |
T |
A |
4: 113,614,128 (GRCm39) |
I693F |
unknown |
Het |
| Skint5 |
G |
T |
4: 113,743,000 (GRCm39) |
L370M |
unknown |
Het |
| Slc12a1 |
G |
A |
2: 125,059,815 (GRCm39) |
W905* |
probably null |
Het |
| Slc26a9 |
G |
C |
1: 131,691,781 (GRCm39) |
V675L |
probably benign |
Het |
| Slc5a7 |
A |
T |
17: 54,583,990 (GRCm39) |
Y433* |
probably null |
Het |
| Slc7a4 |
A |
G |
16: 17,392,977 (GRCm39) |
I274T |
probably benign |
Het |
| Slmap |
A |
G |
14: 26,148,575 (GRCm39) |
V612A |
probably benign |
Het |
| Spen |
T |
C |
4: 141,206,605 (GRCm39) |
D674G |
unknown |
Het |
| Ssh1 |
T |
C |
5: 114,080,488 (GRCm39) |
T981A |
possibly damaging |
Het |
| Sycp2l |
T |
C |
13: 41,316,580 (GRCm39) |
S180P |
probably benign |
Het |
| Tdrd7 |
C |
A |
4: 45,990,144 (GRCm39) |
S181R |
probably benign |
Het |
| Tsga13 |
C |
A |
6: 30,876,981 (GRCm39) |
D179Y |
possibly damaging |
Het |
| Ttf2 |
T |
G |
3: 100,870,478 (GRCm39) |
Q198H |
possibly damaging |
Het |
| Ugt2b37 |
T |
G |
5: 87,401,971 (GRCm39) |
Y220S |
probably benign |
Het |
| Unc79 |
C |
T |
12: 103,061,235 (GRCm39) |
T1145I |
probably damaging |
Het |
| Unc80 |
T |
A |
1: 66,661,621 (GRCm39) |
M1682K |
probably benign |
Het |
| Vcp |
A |
G |
4: 42,982,891 (GRCm39) |
S652P |
probably damaging |
Het |
| Vmn2r-ps158 |
T |
A |
7: 42,697,310 (GRCm39) |
M789K |
probably damaging |
Het |
| Wrnip1 |
T |
A |
13: 33,000,310 (GRCm39) |
L439* |
probably null |
Het |
| Zfhx2 |
A |
G |
14: 55,304,207 (GRCm39) |
I1259T |
possibly damaging |
Het |
| Zfp369 |
A |
T |
13: 65,439,960 (GRCm39) |
T215S |
probably benign |
Het |
| Zfp64 |
A |
T |
2: 168,767,731 (GRCm39) |
V627E |
probably damaging |
Het |
| Zfp873 |
T |
C |
10: 81,895,773 (GRCm39) |
I168T |
probably benign |
Het |
|
| Other mutations in Thada |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00672:Thada
|
APN |
17 |
84,751,646 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL00902:Thada
|
APN |
17 |
84,755,404 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01634:Thada
|
APN |
17 |
84,700,786 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01689:Thada
|
APN |
17 |
84,754,116 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
IGL01693:Thada
|
APN |
17 |
84,754,072 (GRCm39) |
missense |
probably benign |
|
|
IGL01937:Thada
|
APN |
17 |
84,530,194 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01945:Thada
|
APN |
17 |
84,530,194 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02231:Thada
|
APN |
17 |
84,736,125 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02951:Thada
|
APN |
17 |
84,751,456 (GRCm39) |
missense |
probably benign |
0.16 |
|
IGL03167:Thada
|
APN |
17 |
84,766,277 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL03279:Thada
|
APN |
17 |
84,742,988 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03347:Thada
|
APN |
17 |
84,705,633 (GRCm39) |
missense |
probably damaging |
1.00 |
|
H8562:Thada
|
UTSW |
17 |
84,753,972 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03098:Thada
|
UTSW |
17 |
84,641,569 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0006:Thada
|
UTSW |
17 |
84,533,468 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0052:Thada
|
UTSW |
17 |
84,762,586 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0052:Thada
|
UTSW |
17 |
84,762,586 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0357:Thada
|
UTSW |
17 |
84,538,364 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0388:Thada
|
UTSW |
17 |
84,538,524 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0543:Thada
|
UTSW |
17 |
84,730,591 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0606:Thada
|
UTSW |
17 |
84,723,731 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0630:Thada
|
UTSW |
17 |
84,536,603 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0664:Thada
|
UTSW |
17 |
84,644,257 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0855:Thada
|
UTSW |
17 |
84,744,083 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0972:Thada
|
UTSW |
17 |
84,736,490 (GRCm39) |
splice site |
probably benign |
|
|
R1297:Thada
|
UTSW |
17 |
84,559,863 (GRCm39) |
splice site |
probably benign |
|
|
R1465:Thada
|
UTSW |
17 |
84,744,104 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1465:Thada
|
UTSW |
17 |
84,744,104 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1490:Thada
|
UTSW |
17 |
84,754,029 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R1789:Thada
|
UTSW |
17 |
84,755,462 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1789:Thada
|
UTSW |
17 |
84,755,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1802:Thada
|
UTSW |
17 |
84,771,835 (GRCm39) |
missense |
probably benign |
0.34 |
|
R1831:Thada
|
UTSW |
17 |
84,538,542 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1834:Thada
|
UTSW |
17 |
84,533,432 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R1881:Thada
|
UTSW |
17 |
84,744,130 (GRCm39) |
missense |
probably benign |
0.19 |
|
R1925:Thada
|
UTSW |
17 |
84,751,927 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1969:Thada
|
UTSW |
17 |
84,617,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1970:Thada
|
UTSW |
17 |
84,617,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1971:Thada
|
UTSW |
17 |
84,617,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2149:Thada
|
UTSW |
17 |
84,749,192 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2191:Thada
|
UTSW |
17 |
84,753,949 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2571:Thada
|
UTSW |
17 |
84,762,068 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3405:Thada
|
UTSW |
17 |
84,538,213 (GRCm39) |
splice site |
probably benign |
|
|
R3406:Thada
|
UTSW |
17 |
84,538,213 (GRCm39) |
splice site |
probably benign |
|
|
R3916:Thada
|
UTSW |
17 |
84,749,210 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4044:Thada
|
UTSW |
17 |
84,749,135 (GRCm39) |
missense |
probably benign |
0.41 |
|
R4461:Thada
|
UTSW |
17 |
84,733,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4662:Thada
|
UTSW |
17 |
84,743,078 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4696:Thada
|
UTSW |
17 |
84,733,614 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R4786:Thada
|
UTSW |
17 |
84,766,283 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R4803:Thada
|
UTSW |
17 |
84,580,245 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4835:Thada
|
UTSW |
17 |
84,748,532 (GRCm39) |
splice site |
probably null |
|
|
R4872:Thada
|
UTSW |
17 |
84,754,027 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4898:Thada
|
UTSW |
17 |
84,755,470 (GRCm39) |
splice site |
probably null |
|
|
R4903:Thada
|
UTSW |
17 |
84,559,828 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R4929:Thada
|
UTSW |
17 |
84,751,654 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4959:Thada
|
UTSW |
17 |
84,751,611 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5071:Thada
|
UTSW |
17 |
84,693,960 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5092:Thada
|
UTSW |
17 |
84,751,896 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5398:Thada
|
UTSW |
17 |
84,733,614 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5480:Thada
|
UTSW |
17 |
84,739,682 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5552:Thada
|
UTSW |
17 |
84,736,558 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5575:Thada
|
UTSW |
17 |
84,723,827 (GRCm39) |
splice site |
probably null |
|
|
R5623:Thada
|
UTSW |
17 |
84,499,411 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5688:Thada
|
UTSW |
17 |
84,759,155 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5704:Thada
|
UTSW |
17 |
84,538,329 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6008:Thada
|
UTSW |
17 |
84,744,062 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6013:Thada
|
UTSW |
17 |
84,580,228 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6072:Thada
|
UTSW |
17 |
84,499,434 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R6156:Thada
|
UTSW |
17 |
84,700,795 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6243:Thada
|
UTSW |
17 |
84,744,030 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6449:Thada
|
UTSW |
17 |
84,736,601 (GRCm39) |
missense |
probably benign |
|
|
R6453:Thada
|
UTSW |
17 |
84,723,751 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6474:Thada
|
UTSW |
17 |
84,751,339 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R6732:Thada
|
UTSW |
17 |
84,761,842 (GRCm39) |
splice site |
probably null |
|
|
R6907:Thada
|
UTSW |
17 |
84,700,897 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7117:Thada
|
UTSW |
17 |
84,538,214 (GRCm39) |
splice site |
probably null |
|
|
R7167:Thada
|
UTSW |
17 |
84,538,391 (GRCm39) |
missense |
probably benign |
|
|
R7221:Thada
|
UTSW |
17 |
84,771,794 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7753:Thada
|
UTSW |
17 |
84,559,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7809:Thada
|
UTSW |
17 |
84,759,265 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R7882:Thada
|
UTSW |
17 |
84,736,624 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7971:Thada
|
UTSW |
17 |
84,580,197 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8004:Thada
|
UTSW |
17 |
84,499,633 (GRCm39) |
missense |
probably benign |
|
|
R8153:Thada
|
UTSW |
17 |
84,700,855 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8254:Thada
|
UTSW |
17 |
84,533,468 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8426:Thada
|
UTSW |
17 |
84,530,131 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8438:Thada
|
UTSW |
17 |
84,743,057 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8670:Thada
|
UTSW |
17 |
84,739,774 (GRCm39) |
missense |
probably benign |
0.16 |
|
R8679:Thada
|
UTSW |
17 |
84,536,637 (GRCm39) |
missense |
probably benign |
0.28 |
|
R8952:Thada
|
UTSW |
17 |
84,736,524 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8983:Thada
|
UTSW |
17 |
84,538,515 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9009:Thada
|
UTSW |
17 |
84,759,203 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R9050:Thada
|
UTSW |
17 |
84,736,629 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9091:Thada
|
UTSW |
17 |
84,538,589 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9225:Thada
|
UTSW |
17 |
84,749,172 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9251:Thada
|
UTSW |
17 |
84,538,564 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9270:Thada
|
UTSW |
17 |
84,538,589 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9299:Thada
|
UTSW |
17 |
84,749,205 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9337:Thada
|
UTSW |
17 |
84,749,205 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9360:Thada
|
UTSW |
17 |
84,499,410 (GRCm39) |
missense |
probably benign |
|
|
R9416:Thada
|
UTSW |
17 |
84,766,292 (GRCm39) |
nonsense |
probably null |
|
|
R9484:Thada
|
UTSW |
17 |
84,736,619 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9584:Thada
|
UTSW |
17 |
84,733,605 (GRCm39) |
missense |
probably benign |
|
|
R9631:Thada
|
UTSW |
17 |
84,538,584 (GRCm39) |
missense |
probably benign |
0.17 |
|
Z1176:Thada
|
UTSW |
17 |
84,751,858 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCGATTAGCACACTTACCGAG -3'
(R):5'- AGTGTGCATCATGTACCAATAAAGC -3'
Sequencing Primer
(F):5'- TCGATTAGCACACTTACCGAGAATGG -3'
(R):5'- CCAATAAAGCTCTTGTTACTGGCTG -3'
|
| Posted On |
2019-10-07 |
Incidental Mutation