Incidental Mutation 'R7479:Mtcl1'
| ID |
579704 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Mtcl1
|
| Ensembl Gene |
ENSMUSG00000052105 |
| Gene Name |
microtubule crosslinking factor 1 |
| Synonyms |
1110012J17Rik, Soga2, t8219b25 |
| MMRRC Submission |
045553-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.154)
|
| Stock # |
R7479 (G1)
|
| Quality Score |
216.009 |
|
Status
|
Not validated
|
| Chromosome |
17 |
| Chromosomal Location |
66643977-66756745 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 66686485 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 807
(V807A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000083899
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000086693]
[ENSMUST00000097291]
[ENSMUST00000145347]
[ENSMUST00000177034]
|
| AlphaFold |
Q3UHU5 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000086693
AA Change: V807A
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000083899
Gene: ENSMUSG00000052105
AA Change: V807A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
23 |
42 |
N/A |
INTRINSIC |
|
low complexity region
|
54 |
98 |
N/A |
INTRINSIC |
|
low complexity region
|
99 |
120 |
N/A |
INTRINSIC |
|
low complexity region
|
127 |
132 |
N/A |
INTRINSIC |
|
low complexity region
|
166 |
183 |
N/A |
INTRINSIC |
|
low complexity region
|
240 |
259 |
N/A |
INTRINSIC |
|
low complexity region
|
273 |
290 |
N/A |
INTRINSIC |
|
SCOP:d1fxkc_
|
332 |
466 |
3e-7 |
SMART |
|
Blast:BRLZ
|
339 |
362 |
1e-5 |
BLAST |
|
Pfam:DUF3166
|
493 |
587 |
1.8e-34 |
PFAM |
|
Pfam:DUF3166
|
622 |
714 |
3.8e-39 |
PFAM |
|
low complexity region
|
843 |
859 |
N/A |
INTRINSIC |
|
low complexity region
|
896 |
910 |
N/A |
INTRINSIC |
|
low complexity region
|
962 |
973 |
N/A |
INTRINSIC |
|
low complexity region
|
1049 |
1062 |
N/A |
INTRINSIC |
|
coiled coil region
|
1120 |
1159 |
N/A |
INTRINSIC |
|
Pfam:DUF4482
|
1220 |
1344 |
3e-40 |
PFAM |
|
low complexity region
|
1464 |
1476 |
N/A |
INTRINSIC |
|
low complexity region
|
1672 |
1681 |
N/A |
INTRINSIC |
|
low complexity region
|
1912 |
1924 |
N/A |
INTRINSIC |
|
low complexity region
|
1931 |
1943 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000097291
AA Change: V807A
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000094894
Gene: ENSMUSG00000052105
AA Change: V807A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
23 |
42 |
N/A |
INTRINSIC |
|
low complexity region
|
54 |
98 |
N/A |
INTRINSIC |
|
low complexity region
|
99 |
120 |
N/A |
INTRINSIC |
|
low complexity region
|
127 |
132 |
N/A |
INTRINSIC |
|
low complexity region
|
166 |
183 |
N/A |
INTRINSIC |
|
low complexity region
|
240 |
259 |
N/A |
INTRINSIC |
|
low complexity region
|
273 |
290 |
N/A |
INTRINSIC |
|
SCOP:d1fxkc_
|
332 |
466 |
3e-7 |
SMART |
|
Blast:BRLZ
|
339 |
362 |
1e-5 |
BLAST |
|
Pfam:DUF3166
|
492 |
588 |
1.8e-43 |
PFAM |
|
Pfam:DUF3166
|
621 |
716 |
5e-19 |
PFAM |
|
low complexity region
|
843 |
859 |
N/A |
INTRINSIC |
|
low complexity region
|
896 |
910 |
N/A |
INTRINSIC |
|
low complexity region
|
962 |
973 |
N/A |
INTRINSIC |
|
low complexity region
|
1049 |
1062 |
N/A |
INTRINSIC |
|
coiled coil region
|
1120 |
1159 |
N/A |
INTRINSIC |
|
Pfam:DUF4482
|
1220 |
1392 |
3.9e-49 |
PFAM |
|
low complexity region
|
1464 |
1476 |
N/A |
INTRINSIC |
|
low complexity region
|
1672 |
1681 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000145347
AA Change: V358A
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000121387
Gene: ENSMUSG00000052105
AA Change: V358A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF3166
|
43 |
139 |
9.1e-44 |
PFAM |
|
Pfam:DUF3166
|
172 |
267 |
2.5e-19 |
PFAM |
|
low complexity region
|
394 |
410 |
N/A |
INTRINSIC |
|
low complexity region
|
447 |
461 |
N/A |
INTRINSIC |
|
low complexity region
|
513 |
524 |
N/A |
INTRINSIC |
|
low complexity region
|
600 |
613 |
N/A |
INTRINSIC |
|
coiled coil region
|
671 |
710 |
N/A |
INTRINSIC |
|
Pfam:DUF4482
|
771 |
910 |
4.6e-49 |
PFAM |
|
low complexity region
|
1015 |
1027 |
N/A |
INTRINSIC |
|
low complexity region
|
1223 |
1232 |
N/A |
INTRINSIC |
|
low complexity region
|
1463 |
1475 |
N/A |
INTRINSIC |
|
low complexity region
|
1482 |
1494 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000177034
AA Change: V455A
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000135690
Gene: ENSMUSG00000052105
AA Change: V455A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF3166
|
140 |
236 |
1.5e-43 |
PFAM |
|
Pfam:DUF3166
|
269 |
364 |
4e-19 |
PFAM |
|
low complexity region
|
491 |
507 |
N/A |
INTRINSIC |
|
low complexity region
|
544 |
558 |
N/A |
INTRINSIC |
|
low complexity region
|
610 |
621 |
N/A |
INTRINSIC |
|
coiled coil region
|
642 |
674 |
N/A |
INTRINSIC |
|
low complexity region
|
738 |
751 |
N/A |
INTRINSIC |
|
coiled coil region
|
809 |
848 |
N/A |
INTRINSIC |
|
Pfam:DUF4482
|
909 |
1042 |
4e-49 |
PFAM |
|
low complexity region
|
1161 |
1173 |
N/A |
INTRINSIC |
|
low complexity region
|
1369 |
1378 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.5%
- 20x: 98.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Global or Purkinje cell-specific homozygous knockout affects Purkinje cell axon and dendrite morphology, resulting in abnormal motor function. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 70 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700003H04Rik |
T |
A |
3: 124,372,142 (GRCm39) |
M81L |
probably benign |
Het |
| Ano9 |
T |
C |
7: 140,682,348 (GRCm39) |
T667A |
probably damaging |
Het |
| Anpep |
T |
A |
7: 79,485,118 (GRCm39) |
I623F |
probably benign |
Het |
| Apba2 |
T |
C |
7: 64,389,607 (GRCm39) |
I501T |
possibly damaging |
Het |
| Ascc3 |
T |
A |
10: 50,525,895 (GRCm39) |
Y536N |
probably damaging |
Het |
| B4galt1 |
T |
C |
4: 40,823,587 (GRCm39) |
Y168C |
probably damaging |
Het |
| C1ra |
G |
A |
6: 124,494,684 (GRCm39) |
E316K |
probably benign |
Het |
| C2 |
A |
G |
17: 35,082,441 (GRCm39) |
C647R |
probably damaging |
Het |
| Cnot4 |
G |
A |
6: 35,001,083 (GRCm39) |
T604I |
probably benign |
Het |
| Col11a1 |
C |
T |
3: 113,896,218 (GRCm39) |
T506I |
unknown |
Het |
| Cr2 |
A |
C |
1: 194,840,718 (GRCm39) |
|
probably null |
Het |
| Ctsm |
A |
T |
13: 61,685,569 (GRCm39) |
V281D |
probably damaging |
Het |
| Cyp2c69 |
T |
C |
19: 39,870,001 (GRCm39) |
I74V |
probably benign |
Het |
| Dennd4c |
T |
A |
4: 86,717,590 (GRCm39) |
V529D |
probably damaging |
Het |
| Dlgap3 |
C |
A |
4: 127,088,418 (GRCm39) |
H5N |
possibly damaging |
Het |
| Dusp10 |
C |
A |
1: 183,769,617 (GRCm39) |
H194Q |
probably damaging |
Het |
| Eln |
C |
G |
5: 134,736,429 (GRCm39) |
G753A |
unknown |
Het |
| Emb |
T |
A |
13: 117,385,962 (GRCm39) |
N118K |
possibly damaging |
Het |
| Fam184a |
C |
T |
10: 53,531,110 (GRCm39) |
V755I |
probably benign |
Het |
| Fryl |
A |
G |
5: 73,254,904 (GRCm39) |
I846T |
possibly damaging |
Het |
| Gabbr2 |
T |
A |
4: 46,681,166 (GRCm39) |
I722F |
probably damaging |
Het |
| Gabrb3 |
T |
A |
7: 57,474,171 (GRCm39) |
D362E |
possibly damaging |
Het |
| Galnt2 |
G |
A |
8: 125,061,077 (GRCm39) |
G357D |
probably damaging |
Het |
| Gbx2 |
A |
T |
1: 89,858,373 (GRCm39) |
S35R |
probably benign |
Het |
| Glg1 |
A |
G |
8: 111,924,367 (GRCm39) |
I207T |
possibly damaging |
Het |
| Gm10192 |
A |
T |
4: 97,071,272 (GRCm39) |
N44K |
unknown |
Het |
| Gpd1 |
A |
G |
15: 99,617,984 (GRCm39) |
D123G |
probably benign |
Het |
| Grm2 |
A |
T |
9: 106,531,050 (GRCm39) |
D146E |
possibly damaging |
Het |
| Gsg1l2 |
A |
G |
11: 67,676,032 (GRCm39) |
D132G |
probably benign |
Het |
| Hecw1 |
C |
T |
13: 14,515,425 (GRCm39) |
G236R |
probably damaging |
Het |
| Hif3a |
G |
A |
7: 16,776,560 (GRCm39) |
T462I |
possibly damaging |
Het |
| Hspg2 |
C |
T |
4: 137,266,714 (GRCm39) |
A1934V |
probably benign |
Het |
| Il7r |
C |
T |
15: 9,513,117 (GRCm39) |
A131T |
probably damaging |
Het |
| Itga6 |
C |
T |
2: 71,668,680 (GRCm39) |
R540* |
probably null |
Het |
| Kcnh2 |
A |
G |
5: 24,530,490 (GRCm39) |
|
probably null |
Het |
| Kcnq4 |
C |
T |
4: 120,573,022 (GRCm39) |
A260T |
probably damaging |
Het |
| Lrp1b |
T |
C |
2: 40,691,517 (GRCm39) |
N3434S |
|
Het |
| Lrrc41 |
C |
T |
4: 115,946,238 (GRCm39) |
P318S |
probably damaging |
Het |
| Map4 |
G |
A |
9: 109,897,892 (GRCm39) |
G873R |
possibly damaging |
Het |
| Med24 |
A |
G |
11: 98,595,787 (GRCm39) |
I968T |
possibly damaging |
Het |
| Mfap5 |
T |
C |
6: 122,503,821 (GRCm39) |
|
probably null |
Het |
| Mug1 |
T |
A |
6: 121,855,467 (GRCm39) |
S934T |
possibly damaging |
Het |
| Nckap5l |
C |
A |
15: 99,321,127 (GRCm39) |
V1218F |
probably damaging |
Het |
| Nek1 |
T |
A |
8: 61,583,179 (GRCm39) |
D1272E |
probably benign |
Het |
| Nkx2-4 |
T |
C |
2: 146,926,088 (GRCm39) |
E258G |
probably benign |
Het |
| Polr1a |
T |
A |
6: 71,913,281 (GRCm39) |
V545E |
probably damaging |
Het |
| Ppp1r9b |
A |
G |
11: 94,882,858 (GRCm39) |
D162G |
possibly damaging |
Het |
| Rhot2 |
A |
G |
17: 26,059,723 (GRCm39) |
L367P |
probably damaging |
Het |
| Ripk2 |
A |
G |
4: 16,155,154 (GRCm39) |
F122L |
probably benign |
Het |
| Scn11a |
T |
C |
9: 119,588,941 (GRCm39) |
T1322A |
probably benign |
Het |
| Scn8a |
T |
A |
15: 100,853,358 (GRCm39) |
L115Q |
probably damaging |
Het |
| Sel1l3 |
G |
T |
5: 53,274,462 (GRCm39) |
P1006Q |
probably damaging |
Het |
| Septin11 |
A |
T |
5: 93,304,804 (GRCm39) |
N207I |
probably damaging |
Het |
| Sez6l2 |
C |
T |
7: 126,562,831 (GRCm39) |
T669I |
probably damaging |
Het |
| Sfxn4 |
T |
A |
19: 60,847,112 (GRCm39) |
D57V |
possibly damaging |
Het |
| Smarca2 |
T |
A |
19: 26,617,887 (GRCm39) |
V306D |
probably benign |
Het |
| Srgap3 |
C |
T |
6: 112,712,794 (GRCm39) |
|
probably null |
Het |
| Tas2r134 |
T |
C |
2: 51,517,541 (GRCm39) |
F7L |
not run |
Het |
| Tbcd |
T |
C |
11: 121,383,431 (GRCm39) |
|
probably null |
Het |
| Tcn2 |
G |
A |
11: 3,867,703 (GRCm39) |
A413V |
probably damaging |
Het |
| Tdp1 |
T |
C |
12: 99,857,654 (GRCm39) |
V71A |
probably benign |
Het |
| Tjp1 |
T |
C |
7: 64,950,928 (GRCm39) |
T1649A |
probably damaging |
Het |
| Tnc |
T |
C |
4: 63,935,865 (GRCm39) |
E357G |
possibly damaging |
Het |
| Tnrc6b |
A |
G |
15: 80,773,327 (GRCm39) |
T1158A |
probably benign |
Het |
| Ttn |
C |
A |
2: 76,568,952 (GRCm39) |
E27314* |
probably null |
Het |
| Vps35 |
G |
T |
8: 85,997,434 (GRCm39) |
T512K |
probably benign |
Het |
| Zfp40 |
A |
T |
17: 23,396,292 (GRCm39) |
S98R |
probably benign |
Het |
| Zfp764l1 |
C |
T |
7: 126,992,496 (GRCm39) |
C38Y |
probably null |
Het |
| Zfp945 |
A |
T |
17: 23,070,340 (GRCm39) |
C541S |
possibly damaging |
Het |
| Zfp976 |
T |
A |
7: 42,262,603 (GRCm39) |
E412D |
probably benign |
Het |
|
| Other mutations in Mtcl1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00092:Mtcl1
|
APN |
17 |
66,651,314 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01774:Mtcl1
|
APN |
17 |
66,692,880 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01918:Mtcl1
|
APN |
17 |
66,675,263 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
IGL02000:Mtcl1
|
APN |
17 |
66,661,185 (GRCm39) |
missense |
probably benign |
0.19 |
|
IGL02074:Mtcl1
|
APN |
17 |
66,673,463 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
IGL02338:Mtcl1
|
APN |
17 |
66,686,965 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02597:Mtcl1
|
APN |
17 |
66,645,016 (GRCm39) |
missense |
probably benign |
|
|
IGL03034:Mtcl1
|
APN |
17 |
66,651,193 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03120:Mtcl1
|
APN |
17 |
66,686,378 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL03184:Mtcl1
|
APN |
17 |
66,661,209 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03240:Mtcl1
|
APN |
17 |
66,645,014 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03294:Mtcl1
|
APN |
17 |
66,645,014 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03332:Mtcl1
|
APN |
17 |
66,645,014 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4378001:Mtcl1
|
UTSW |
17 |
66,745,274 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4520001:Mtcl1
|
UTSW |
17 |
66,692,907 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R0110:Mtcl1
|
UTSW |
17 |
66,665,109 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R0113:Mtcl1
|
UTSW |
17 |
66,661,237 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R0321:Mtcl1
|
UTSW |
17 |
66,686,426 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0366:Mtcl1
|
UTSW |
17 |
66,645,124 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0629:Mtcl1
|
UTSW |
17 |
66,645,137 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1466:Mtcl1
|
UTSW |
17 |
66,687,430 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1466:Mtcl1
|
UTSW |
17 |
66,687,430 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1467:Mtcl1
|
UTSW |
17 |
66,755,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1467:Mtcl1
|
UTSW |
17 |
66,755,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1471:Mtcl1
|
UTSW |
17 |
66,686,143 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1650:Mtcl1
|
UTSW |
17 |
66,692,871 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1754:Mtcl1
|
UTSW |
17 |
66,687,178 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1855:Mtcl1
|
UTSW |
17 |
66,686,509 (GRCm39) |
missense |
probably benign |
|
|
R1882:Mtcl1
|
UTSW |
17 |
66,686,315 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1935:Mtcl1
|
UTSW |
17 |
66,686,409 (GRCm39) |
missense |
probably benign |
0.10 |
|
R2063:Mtcl1
|
UTSW |
17 |
66,653,350 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2132:Mtcl1
|
UTSW |
17 |
66,650,618 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2197:Mtcl1
|
UTSW |
17 |
66,673,427 (GRCm39) |
missense |
probably benign |
|
|
R3196:Mtcl1
|
UTSW |
17 |
66,650,829 (GRCm39) |
missense |
probably benign |
0.07 |
|
R3877:Mtcl1
|
UTSW |
17 |
66,649,949 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4116:Mtcl1
|
UTSW |
17 |
66,673,476 (GRCm39) |
missense |
probably benign |
|
|
R4204:Mtcl1
|
UTSW |
17 |
66,745,256 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4373:Mtcl1
|
UTSW |
17 |
66,687,074 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4396:Mtcl1
|
UTSW |
17 |
66,651,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4591:Mtcl1
|
UTSW |
17 |
66,655,506 (GRCm39) |
missense |
probably benign |
0.07 |
|
R4610:Mtcl1
|
UTSW |
17 |
66,684,882 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4681:Mtcl1
|
UTSW |
17 |
66,756,139 (GRCm39) |
missense |
unknown |
|
|
R4922:Mtcl1
|
UTSW |
17 |
66,655,474 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4992:Mtcl1
|
UTSW |
17 |
66,649,834 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5169:Mtcl1
|
UTSW |
17 |
66,650,818 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5542:Mtcl1
|
UTSW |
17 |
66,691,354 (GRCm39) |
intron |
probably benign |
|
|
R5804:Mtcl1
|
UTSW |
17 |
66,650,132 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5998:Mtcl1
|
UTSW |
17 |
66,675,275 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6163:Mtcl1
|
UTSW |
17 |
66,686,326 (GRCm39) |
missense |
probably benign |
0.10 |
|
R6191:Mtcl1
|
UTSW |
17 |
66,650,521 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6254:Mtcl1
|
UTSW |
17 |
66,665,129 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6260:Mtcl1
|
UTSW |
17 |
66,650,536 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6524:Mtcl1
|
UTSW |
17 |
66,655,280 (GRCm39) |
missense |
probably benign |
0.15 |
|
R6884:Mtcl1
|
UTSW |
17 |
66,745,197 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7199:Mtcl1
|
UTSW |
17 |
66,647,534 (GRCm39) |
missense |
probably benign |
0.13 |
|
R7431:Mtcl1
|
UTSW |
17 |
66,649,901 (GRCm39) |
nonsense |
probably null |
|
|
R7564:Mtcl1
|
UTSW |
17 |
66,678,322 (GRCm39) |
missense |
probably benign |
|
|
R7608:Mtcl1
|
UTSW |
17 |
66,650,300 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7691:Mtcl1
|
UTSW |
17 |
66,687,352 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7847:Mtcl1
|
UTSW |
17 |
66,651,328 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7908:Mtcl1
|
UTSW |
17 |
66,678,325 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R8262:Mtcl1
|
UTSW |
17 |
66,650,653 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8324:Mtcl1
|
UTSW |
17 |
66,743,212 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8477:Mtcl1
|
UTSW |
17 |
66,684,942 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8927:Mtcl1
|
UTSW |
17 |
66,755,628 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8928:Mtcl1
|
UTSW |
17 |
66,755,628 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9016:Mtcl1
|
UTSW |
17 |
66,651,062 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9048:Mtcl1
|
UTSW |
17 |
66,678,331 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9059:Mtcl1
|
UTSW |
17 |
66,650,606 (GRCm39) |
missense |
probably benign |
0.04 |
|
R9221:Mtcl1
|
UTSW |
17 |
66,650,879 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9327:Mtcl1
|
UTSW |
17 |
66,645,130 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9398:Mtcl1
|
UTSW |
17 |
66,755,462 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R9762:Mtcl1
|
UTSW |
17 |
66,673,347 (GRCm39) |
missense |
probably benign |
0.00 |
|
X0065:Mtcl1
|
UTSW |
17 |
66,686,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Mtcl1
|
UTSW |
17 |
66,650,723 (GRCm39) |
missense |
probably benign |
0.20 |
|
Z1176:Mtcl1
|
UTSW |
17 |
66,686,455 (GRCm39) |
missense |
probably benign |
0.01 |
|
Z1177:Mtcl1
|
UTSW |
17 |
66,651,290 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CTGAAAGCCTTCATCCTCACATTG -3'
(R):5'- ACAGTGATGCCGAGAGTGAC -3'
Sequencing Primer
(F):5'- CACATTGATGGTCTCCAACAAGTGG -3'
(R):5'- AGAGTGACGCGGGCAAG -3'
|
| Posted On |
2019-10-07 |
Incidental Mutation