Mutagenetix > Incidental Mutation

Incidental Mutation 'R7483:Ankrd17'

579906

Institutional Source

Beutler Lab

Gene Symbol

Ankrd17

Ensembl Gene

ENSMUSG00000055204

Gene Name

ankyrin repeat domain 17

Synonyms

Gtar, A130069E23Rik, 4933425K22Rik

MMRRC Submission

045557-MU

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R7483 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

90375025-90514436 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 90447855 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Serine to Proline at position 229 (S229P)

Ref Sequence

ENSEMBL: ENSMUSP00000014421 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000014421] [ENSMUST00000081914] [ENSMUST00000168058] [ENSMUST00000197021] [ENSMUST00000218526]

AlphaFold

Q99NH0

Predicted Effect

probably benign
Transcript: ENSMUST00000014421
AA Change: S229P

PolyPhen 2 Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)

SMART Domains

Protein: ENSMUSP00000014421
Gene: ENSMUSG00000055204
AA Change: S229P

Domain	Start	End	E-Value	Type
low complexity region	6	40	N/A	INTRINSIC
low complexity region	55	71	N/A	INTRINSIC
low complexity region	82	130	N/A	INTRINSIC
ANK	229	258	8.62e1	SMART
ANK	262	291	3.31e-1	SMART
ANK	296	325	3.51e-5	SMART
ANK	329	358	1.33e-5	SMART
ANK	362	391	3.46e-4	SMART
ANK	396	425	3.23e-4	SMART
ANK	429	458	1.61e-4	SMART
ANK	462	491	1.46e-2	SMART
ANK	495	524	3.88e-7	SMART
ANK	529	558	4.19e-3	SMART
ANK	559	588	1.76e-5	SMART
ANK	592	621	3.51e-5	SMART
ANK	625	654	5.62e-4	SMART
ANK	659	688	1.29e-3	SMART
ANK	692	721	1.44e-1	SMART
coiled coil region	800	883	N/A	INTRINSIC
low complexity region	890	903	N/A	INTRINSIC
low complexity region	955	968	N/A	INTRINSIC
low complexity region	986	997	N/A	INTRINSIC
low complexity region	1046	1060	N/A	INTRINSIC
ANK	1078	1107	2.13e-4	SMART
ANK	1111	1140	8.19e-6	SMART
ANK	1145	1174	1.68e-2	SMART
ANK	1178	1207	1.61e-4	SMART
ANK	1213	1242	1.43e-5	SMART
ANK	1247	1276	1.83e-3	SMART
ANK	1280	1309	3.91e-3	SMART
ANK	1315	1344	1.93e-2	SMART
ANK	1348	1377	8.78e-6	SMART
ANK	1381	1410	7.59e-1	SMART
coiled coil region	1454	1522	N/A	INTRINSIC
low complexity region	1597	1611	N/A	INTRINSIC
low complexity region	1616	1636	N/A	INTRINSIC
KH	1720	1790	8.31e-14	SMART
low complexity region	1816	1827	N/A	INTRINSIC
low complexity region	1834	1850	N/A	INTRINSIC
low complexity region	1946	1989	N/A	INTRINSIC
low complexity region	1996	2024	N/A	INTRINSIC
low complexity region	2035	2052	N/A	INTRINSIC
low complexity region	2068	2077	N/A	INTRINSIC
low complexity region	2086	2110	N/A	INTRINSIC
low complexity region	2175	2189	N/A	INTRINSIC
low complexity region	2348	2365	N/A	INTRINSIC
low complexity region	2392	2411	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000081914
AA Change: S229P

PolyPhen 2 Score 0.191 (Sensitivity: 0.92; Specificity: 0.87)

SMART Domains

Protein: ENSMUSP00000080587
Gene: ENSMUSG00000055204
AA Change: S229P

Domain	Start	End	E-Value	Type
low complexity region	6	40	N/A	INTRINSIC
low complexity region	55	71	N/A	INTRINSIC
low complexity region	82	130	N/A	INTRINSIC
ANK	229	258	8.62e1	SMART
ANK	262	291	3.31e-1	SMART
ANK	296	325	3.51e-5	SMART
ANK	329	358	1.33e-5	SMART
ANK	362	391	3.46e-4	SMART
ANK	396	425	3.23e-4	SMART
ANK	429	458	1.61e-4	SMART
ANK	462	491	1.46e-2	SMART
ANK	495	524	3.88e-7	SMART
ANK	529	558	4.19e-3	SMART
ANK	559	588	1.76e-5	SMART
ANK	592	621	3.51e-5	SMART
ANK	625	654	5.62e-4	SMART
ANK	659	688	1.29e-3	SMART
ANK	692	721	1.44e-1	SMART
low complexity region	795	809	N/A	INTRINSIC
ANK	827	856	2.13e-4	SMART
ANK	860	889	8.19e-6	SMART
ANK	894	923	1.68e-2	SMART
ANK	927	956	1.61e-4	SMART
ANK	962	991	1.43e-5	SMART
ANK	996	1025	1.83e-3	SMART
ANK	1029	1058	3.91e-3	SMART
ANK	1064	1093	1.93e-2	SMART
ANK	1097	1126	8.78e-6	SMART
ANK	1130	1159	7.59e-1	SMART
coiled coil region	1203	1271	N/A	INTRINSIC
low complexity region	1346	1360	N/A	INTRINSIC
low complexity region	1365	1385	N/A	INTRINSIC
KH	1469	1539	8.31e-14	SMART
low complexity region	1565	1576	N/A	INTRINSIC
low complexity region	1583	1599	N/A	INTRINSIC
low complexity region	1695	1738	N/A	INTRINSIC
low complexity region	1745	1773	N/A	INTRINSIC
low complexity region	1784	1801	N/A	INTRINSIC
low complexity region	1817	1826	N/A	INTRINSIC
low complexity region	1835	1859	N/A	INTRINSIC
low complexity region	1924	1938	N/A	INTRINSIC
low complexity region	2097	2114	N/A	INTRINSIC
low complexity region	2141	2160	N/A	INTRINSIC

Predicted Effect

SMART Domains

Protein: ENSMUSP00000128960
Gene: ENSMUSG00000055204
AA Change: S229P

Domain	Start	End	E-Value	Type
low complexity region	6	40	N/A	INTRINSIC
low complexity region	55	71	N/A	INTRINSIC
low complexity region	82	130	N/A	INTRINSIC
ANK	229	258	8.62e1	SMART
ANK	262	291	3.31e-1	SMART
ANK	296	325	3.51e-5	SMART
ANK	329	358	1.33e-5	SMART
ANK	362	391	3.46e-4	SMART
ANK	396	425	3.23e-4	SMART
ANK	429	458	1.61e-4	SMART
ANK	462	491	1.46e-2	SMART
ANK	495	524	3.88e-7	SMART
ANK	529	558	4.19e-3	SMART
ANK	559	588	1.76e-5	SMART
ANK	592	621	3.51e-5	SMART
ANK	625	654	5.62e-4	SMART
ANK	659	688	1.29e-3	SMART
ANK	692	721	1.44e-1	SMART
coiled coil region	800	883	N/A	INTRINSIC
low complexity region	890	903	N/A	INTRINSIC
low complexity region	955	968	N/A	INTRINSIC
low complexity region	986	997	N/A	INTRINSIC
low complexity region	1046	1060	N/A	INTRINSIC
ANK	1078	1107	2.13e-4	SMART
ANK	1111	1140	8.19e-6	SMART
ANK	1145	1174	1.68e-2	SMART
ANK	1178	1207	1.61e-4	SMART
ANK	1213	1242	1.43e-5	SMART
ANK	1247	1276	1.83e-3	SMART
ANK	1280	1309	3.91e-3	SMART
ANK	1315	1344	1.93e-2	SMART
ANK	1348	1377	8.78e-6	SMART
ANK	1381	1410	7.59e-1	SMART
coiled coil region	1454	1522	N/A	INTRINSIC

Predicted Effect

unknown
Transcript: ENSMUST00000197021
AA Change: S120P

SMART Domains

Protein: ENSMUSP00000142575
Gene: ENSMUSG00000055204
AA Change: S120P

Domain	Start	End	E-Value	Type
ANK	120	149	5.4e-1	SMART
ANK	153	182	2e-3	SMART
ANK	187	216	2.2e-7	SMART
ANK	220	249	8.2e-8	SMART
ANK	253	282	2.2e-6	SMART
ANK	287	316	2.1e-6	SMART
ANK	320	349	9.9e-7	SMART
ANK	353	382	9.5e-5	SMART
ANK	386	415	2.4e-9	SMART
ANK	420	449	2.6e-5	SMART
ANK	450	479	1.1e-7	SMART
ANK	483	512	2.2e-7	SMART
ANK	516	545	3.5e-6	SMART
ANK	550	579	7.9e-6	SMART
ANK	583	612	8.9e-4	SMART
coiled coil region	691	774	N/A	INTRINSIC
low complexity region	781	794	N/A	INTRINSIC
low complexity region	846	859	N/A	INTRINSIC
low complexity region	877	888	N/A	INTRINSIC
low complexity region	937	951	N/A	INTRINSIC
ANK	969	998	1.4e-6	SMART
ANK	1002	1031	5.3e-8	SMART
ANK	1036	1065	1e-4	SMART
ANK	1069	1098	1e-6	SMART
ANK	1104	1133	9.1e-8	SMART
ANK	1138	1167	1.2e-5	SMART
ANK	1171	1200	2.5e-5	SMART
ANK	1206	1235	1.2e-4	SMART
ANK	1239	1268	5.5e-8	SMART
ANK	1272	1301	4.7e-3	SMART
coiled coil region	1345	1413	N/A	INTRINSIC
low complexity region	1488	1502	N/A	INTRINSIC
low complexity region	1507	1527	N/A	INTRINSIC
KH	1611	1681	5.1e-16	SMART
low complexity region	1707	1718	N/A	INTRINSIC
low complexity region	1725	1741	N/A	INTRINSIC
low complexity region	1837	1880	N/A	INTRINSIC
low complexity region	1887	1915	N/A	INTRINSIC
low complexity region	1926	1943	N/A	INTRINSIC
low complexity region	1959	1968	N/A	INTRINSIC
low complexity region	1977	2001	N/A	INTRINSIC
low complexity region	2066	2080	N/A	INTRINSIC
low complexity region	2239	2256	N/A	INTRINSIC
low complexity region	2283	2302	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000218526
AA Change: S229P

PolyPhen 2 Score 0.009 (Sensitivity: 0.96; Specificity: 0.77)

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.7%
20x: 99.0%

Validation Efficiency

MGI Phenotype

FUNCTION: This gene encodes a protein with ankyrin repeats, which are associated with protein-protein interactions. Studies suggest that this protein is involved in liver development. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a null mutation display embryonic lethality during organogenesis with hemorrhages, impaired vascular smooth muscle cell development, impaired vascular integrity, and growth retardation. [provided by MGI curators]

Allele List at MGI

All alleles(133) : Targeted(4) Gene trapped(129)

Other mutations in this stock

Total: 92 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Acad10	A	T	5: 121,794,075 (GRCm39)		probably null	Het
Ahnak	T	C	19: 8,982,186 (GRCm39)	S1157P	probably damaging	Het
Akap12	T	G	10: 4,303,967 (GRCm39)	V364G	probably benign	Het
Apof	A	T	10: 128,104,636 (GRCm39)	Y5F	probably benign	Het
Arhgap24	T	A	5: 102,989,174 (GRCm39)	M94K	probably benign	Het
Ash2l	G	T	8: 26,312,798 (GRCm39)	D479E	probably damaging	Het
Atp8a2	A	T	14: 60,245,824 (GRCm39)	C623S	probably benign	Het
Bmper	T	A	9: 23,395,238 (GRCm39)	N656K	probably benign	Het
Braf	T	C	6: 39,604,772 (GRCm39)	I619V	possibly damaging	Het
Brwd1	T	C	16: 95,857,373 (GRCm39)	R396G	probably damaging	Het
Car7	A	T	8: 105,276,216 (GRCm39)	T234S	probably benign	Het
Catsper4	A	T	4: 133,945,552 (GRCm39)	V169E	probably damaging	Het
Cemip	T	G	7: 83,647,784 (GRCm39)	I99L	probably damaging	Het
Chrna7	C	A	7: 62,754,738 (GRCm39)	V290L	probably damaging	Het
Clip1	A	T	5: 123,755,447 (GRCm39)	D944E	probably benign	Het
Cplane2	A	G	4: 140,947,153 (GRCm39)	D178G	probably damaging	Het
Cyp2c68	T	C	19: 39,677,581 (GRCm39)	T470A	probably benign	Het
Dmbx1	G	T	4: 115,780,908 (GRCm39)	A31D	probably damaging	Het
Dnah7b	T	C	1: 46,214,579 (GRCm39)	F1115L	probably damaging	Het
Dock10	T	C	1: 80,493,283 (GRCm39)	I1897V	probably benign	Het
Efcab3	A	G	11: 105,000,112 (GRCm39)	I234V	probably benign	Het
Eid2b	T	G	7: 27,977,243 (GRCm39)	L13R	probably damaging	Het
Enam	A	G	5: 88,649,679 (GRCm39)	Y396C	probably damaging	Het
Fam161a	A	T	11: 22,971,006 (GRCm39)	T395S	probably damaging	Het
Fat1	A	G	8: 45,476,197 (GRCm39)	R1748G	probably benign	Het
Fdxacb1	C	A	9: 50,681,451 (GRCm39)	T124K	possibly damaging	Het
Fer1l6	A	T	15: 58,513,794 (GRCm39)	D1563V	possibly damaging	Het
Gm20834	T	C	Y: 10,323,226 (GRCm39)	H70R	probably damaging	Het
Gucy2d	T	A	7: 98,098,964 (GRCm39)	M261K	probably damaging	Het
Hcar2	T	A	5: 124,002,861 (GRCm39)	Q214L	probably benign	Het
Hdac11	C	T	6: 91,136,214 (GRCm39)	H75Y	probably damaging	Het
Hoxa2	C	A	6: 52,141,279 (GRCm39)	A116S	probably benign	Het
Ints2	A	G	11: 86,106,444 (GRCm39)	C989R	probably damaging	Het
Jpt1	T	C	11: 115,393,950 (GRCm39)	E36G	probably damaging	Het
Kdm5d	G	A	Y: 914,044 (GRCm39)	R327Q	possibly damaging	Het
Klhl1	T	C	14: 96,584,304 (GRCm39)	M309V	probably benign	Het
Larp4	A	G	15: 99,889,659 (GRCm39)	K193E	probably benign	Het
Lmo3	C	T	6: 138,393,500 (GRCm39)	C40Y	probably damaging	Het
Mcm4	A	G	16: 15,448,306 (GRCm39)	V417A	probably benign	Het
Med8	A	G	4: 118,268,176 (GRCm39)	E34G	probably damaging	Het
Mex3b	G	T	7: 82,517,114 (GRCm39)	A86S	possibly damaging	Het
Muc6	T	C	7: 141,224,245 (GRCm39)	T1646A	unknown	Het
Myo15b	A	T	11: 115,749,570 (GRCm39)	E113D		Het
Myo7a	T	A	7: 97,712,881 (GRCm39)	H1698L	probably benign	Het
Myocos	T	A	1: 162,484,678 (GRCm39)	M44L	unknown	Het
Nalcn	A	G	14: 123,551,499 (GRCm39)	V1036A	probably damaging	Het
Nfrkb	C	T	9: 31,325,328 (GRCm39)	Q924*	probably null	Het
Nol6	A	G	4: 41,117,424 (GRCm39)	L923P	possibly damaging	Het
Nrxn3	T	C	12: 89,477,232 (GRCm39)	Y472H	probably damaging	Het
Nudcd1	A	G	15: 44,269,253 (GRCm39)	Y136H	possibly damaging	Het
Obox2	T	C	7: 15,131,241 (GRCm39)	C116R	probably damaging	Het
Onecut3	A	T	10: 80,331,310 (GRCm39)	S157C	unknown	Het
Or10ak11	A	G	4: 118,687,517 (GRCm39)	V39A	probably damaging	Het
Or11g27	T	A	14: 50,771,472 (GRCm39)	V201D	probably benign	Het
Or2d2b	T	A	7: 106,705,982 (GRCm39)	I29F	probably benign	Het
Or4f15	T	C	2: 111,814,124 (GRCm39)	I98M	probably damaging	Het
Oscp1	C	T	4: 125,967,726 (GRCm39)	R91*	probably null	Het
Pclo	A	T	5: 14,762,606 (GRCm39)	D408V		Het
Pde8a	T	C	7: 80,932,581 (GRCm39)	V81A	probably benign	Het
Pde8b	T	A	13: 95,164,251 (GRCm39)	D653V	probably damaging	Het
Peg10	T	TCCG	6: 4,756,451 (GRCm39)		probably benign	Het
Pik3cg	T	C	12: 32,245,647 (GRCm39)	Y867C	probably damaging	Het
Pkd1l3	GACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCA	GACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCA	8: 110,350,827 (GRCm39)		probably benign	Het
Psd4	A	T	2: 24,294,768 (GRCm39)	D776V	possibly damaging	Het
Ptprb	A	G	10: 116,119,334 (GRCm39)	E156G	probably benign	Het
Rad54b	A	G	4: 11,610,372 (GRCm39)	Y663C	probably damaging	Het
Ranbp3l	T	A	15: 9,030,955 (GRCm39)	V78D	possibly damaging	Het
Rbm12	T	C	2: 155,940,138 (GRCm39)	I45V	unknown	Het
Scn9a	A	G	2: 66,363,692 (GRCm39)	V862A	probably damaging	Het
Sdcbp	T	C	4: 6,393,089 (GRCm39)	I242T	possibly damaging	Het
Slc25a24	A	G	3: 109,066,751 (GRCm39)	T302A	probably damaging	Het
Slc45a3	G	T	1: 131,904,549 (GRCm39)		probably benign	Het
Srpk1	T	C	17: 28,813,192 (GRCm39)	I517M	probably benign	Het
Tmx4	A	G	2: 134,481,581 (GRCm39)	M114T	probably benign	Het
Trhr	T	A	15: 44,092,627 (GRCm39)	V288D	probably damaging	Het
Tspoap1	A	T	11: 87,652,351 (GRCm39)	I42F	probably benign	Het
Ttn	A	T	2: 76,781,856 (GRCm39)	D1063E	unknown	Het
Tusc3	A	G	8: 39,538,635 (GRCm39)	I225V	probably benign	Het
Ugt2b38	A	G	5: 87,571,973 (GRCm39)	S20P	probably damaging	Het
Upf2	A	G	2: 6,032,219 (GRCm39)	T922A	unknown	Het
Usp38	C	T	8: 81,741,190 (GRCm39)		probably benign	Het
Vmn1r216	A	G	13: 23,283,738 (GRCm39)	I140M	probably damaging	Het
Vmn2r115	T	A	17: 23,565,371 (GRCm39)	N419K	possibly damaging	Het
Vmn2r55	C	T	7: 12,404,755 (GRCm39)	G216D	probably benign	Het
Vwa8	A	C	14: 79,219,674 (GRCm39)		probably null	Het
Wnt7b	C	A	15: 85,421,615 (GRCm39)	R349L	possibly damaging	Het
Xbp1	T	C	11: 5,471,098 (GRCm39)	V35A	probably benign	Het
Zan	A	T	5: 137,445,057 (GRCm39)	M1734K	unknown	Het
Zfhx4	A	G	3: 5,477,237 (GRCm39)	E3284G	probably damaging	Het
Zfp458	A	G	13: 67,404,978 (GRCm39)	L487S	possibly damaging	Het
Zfp687	C	T	3: 94,914,841 (GRCm39)	R1220H	probably damaging	Het
Zp1	A	G	19: 10,895,280 (GRCm39)	L324P	possibly damaging	Het

Other mutations in Ankrd17

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00236:Ankrd17	APN	5	90,381,787 (GRCm39)	missense	probably damaging	0.98
IGL00484:Ankrd17	APN	5	90,416,220 (GRCm39)	missense	probably damaging	0.99
IGL01320:Ankrd17	APN	5	90,407,988 (GRCm39)	missense	probably damaging	0.99
IGL01776:Ankrd17	APN	5	90,431,223 (GRCm39)	nonsense	probably null
IGL02093:Ankrd17	APN	5	90,390,822 (GRCm39)	missense	possibly damaging	0.93
IGL02292:Ankrd17	APN	5	90,400,718 (GRCm39)	unclassified	probably benign
IGL02302:Ankrd17	APN	5	90,431,057 (GRCm39)	missense	probably benign	0.23
IGL02472:Ankrd17	APN	5	90,412,010 (GRCm39)	missense	probably damaging	1.00
IGL02705:Ankrd17	APN	5	90,430,974 (GRCm39)	missense	probably benign	0.15
IGL02727:Ankrd17	APN	5	90,392,151 (GRCm39)	missense	possibly damaging	0.93
IGL02884:Ankrd17	APN	5	90,412,616 (GRCm39)	missense	probably damaging	1.00
3-1:Ankrd17	UTSW	5	90,391,013 (GRCm39)	missense	probably damaging	0.99
PIT1430001:Ankrd17	UTSW	5	90,400,832 (GRCm39)	missense	possibly damaging	0.91
R0025:Ankrd17	UTSW	5	90,398,264 (GRCm39)	missense	probably damaging	0.99
R0076:Ankrd17	UTSW	5	90,392,265 (GRCm39)	nonsense	probably null
R0076:Ankrd17	UTSW	5	90,392,265 (GRCm39)	nonsense	probably null
R0271:Ankrd17	UTSW	5	90,402,658 (GRCm39)	missense	possibly damaging	0.90
R0684:Ankrd17	UTSW	5	90,411,857 (GRCm39)	missense	probably damaging	0.99
R1239:Ankrd17	UTSW	5	90,436,535 (GRCm39)	missense	probably damaging	0.99
R1457:Ankrd17	UTSW	5	90,433,705 (GRCm39)	missense	possibly damaging	0.92
R1505:Ankrd17	UTSW	5	90,447,885 (GRCm39)	missense	possibly damaging	0.53
R1766:Ankrd17	UTSW	5	90,412,656 (GRCm39)	missense	possibly damaging	0.95
R1770:Ankrd17	UTSW	5	90,391,235 (GRCm39)	missense	possibly damaging	0.84
R1780:Ankrd17	UTSW	5	90,380,274 (GRCm39)	missense	probably damaging	0.96
R1916:Ankrd17	UTSW	5	90,408,000 (GRCm39)	missense	probably damaging	1.00
R1926:Ankrd17	UTSW	5	90,392,028 (GRCm39)	missense	probably damaging	1.00
R2090:Ankrd17	UTSW	5	90,445,905 (GRCm39)	missense	possibly damaging	0.92
R2153:Ankrd17	UTSW	5	90,381,918 (GRCm39)	missense	probably damaging	0.98
R2279:Ankrd17	UTSW	5	90,412,576 (GRCm39)	missense	probably damaging	1.00
R2420:Ankrd17	UTSW	5	90,437,179 (GRCm39)	missense	possibly damaging	0.94
R3012:Ankrd17	UTSW	5	90,378,727 (GRCm39)	missense	probably damaging	1.00
R3417:Ankrd17	UTSW	5	90,391,772 (GRCm39)	missense	possibly damaging	0.86
R3704:Ankrd17	UTSW	5	90,391,828 (GRCm39)	missense	possibly damaging	0.72
R4581:Ankrd17	UTSW	5	90,430,979 (GRCm39)	missense	possibly damaging	0.67
R4850:Ankrd17	UTSW	5	90,412,645 (GRCm39)	missense	probably damaging	1.00
R4926:Ankrd17	UTSW	5	90,447,891 (GRCm39)	missense	probably damaging	1.00
R5023:Ankrd17	UTSW	5	90,430,727 (GRCm39)	missense	probably damaging	1.00
R5068:Ankrd17	UTSW	5	90,402,667 (GRCm39)	missense	probably damaging	0.96
R5109:Ankrd17	UTSW	5	90,391,395 (GRCm39)	missense	possibly damaging	0.83
R5111:Ankrd17	UTSW	5	90,390,858 (GRCm39)	missense	possibly damaging	0.85
R5214:Ankrd17	UTSW	5	90,431,319 (GRCm39)	missense	possibly damaging	0.48
R5362:Ankrd17	UTSW	5	90,413,404 (GRCm39)	missense	probably damaging	1.00
R5576:Ankrd17	UTSW	5	90,391,083 (GRCm39)	missense	probably benign	0.00
R5615:Ankrd17	UTSW	5	90,431,295 (GRCm39)	missense	possibly damaging	0.88
R5874:Ankrd17	UTSW	5	90,416,656 (GRCm39)	intron	probably benign
R5932:Ankrd17	UTSW	5	90,413,295 (GRCm39)	missense	probably damaging	1.00
R5944:Ankrd17	UTSW	5	90,433,702 (GRCm39)	missense	probably damaging	1.00
R5993:Ankrd17	UTSW	5	90,487,531 (GRCm39)	intron	probably benign
R6052:Ankrd17	UTSW	5	90,401,691 (GRCm39)	missense	probably benign	0.03
R6088:Ankrd17	UTSW	5	90,401,547 (GRCm39)	missense	possibly damaging	0.95
R6306:Ankrd17	UTSW	5	90,392,013 (GRCm39)	missense	probably benign	0.03
R6418:Ankrd17	UTSW	5	90,426,204 (GRCm39)	missense	possibly damaging	0.89
R6663:Ankrd17	UTSW	5	90,411,923 (GRCm39)	missense	probably damaging	1.00
R6758:Ankrd17	UTSW	5	90,411,172 (GRCm39)	missense	probably damaging	1.00
R6782:Ankrd17	UTSW	5	90,402,597 (GRCm39)	missense	possibly damaging	0.91
R6793:Ankrd17	UTSW	5	90,413,371 (GRCm39)	missense	probably damaging	1.00
R6929:Ankrd17	UTSW	5	90,433,384 (GRCm39)	missense	possibly damaging	0.86
R7008:Ankrd17	UTSW	5	90,407,955 (GRCm39)	missense	possibly damaging	0.93
R7051:Ankrd17	UTSW	5	90,514,310 (GRCm39)	unclassified	probably benign
R7077:Ankrd17	UTSW	5	90,433,723 (GRCm39)	missense	possibly damaging	0.92
R7134:Ankrd17	UTSW	5	90,433,382 (GRCm39)	missense	probably benign	0.03
R7134:Ankrd17	UTSW	5	90,380,173 (GRCm39)	missense	probably damaging	0.99
R7138:Ankrd17	UTSW	5	90,390,836 (GRCm39)	missense	probably benign	0.38
R7143:Ankrd17	UTSW	5	90,433,820 (GRCm39)	missense	possibly damaging	0.85
R7173:Ankrd17	UTSW	5	90,407,976 (GRCm39)	missense	possibly damaging	0.95
R7176:Ankrd17	UTSW	5	90,416,594 (GRCm39)	missense	probably damaging	0.99
R7365:Ankrd17	UTSW	5	90,439,010 (GRCm39)	missense	possibly damaging	0.45
R7390:Ankrd17	UTSW	5	90,430,779 (GRCm39)	missense	probably benign	0.13
R7430:Ankrd17	UTSW	5	90,443,516 (GRCm39)	missense	possibly damaging	0.80
R7468:Ankrd17	UTSW	5	90,390,902 (GRCm39)	missense	probably benign
R7492:Ankrd17	UTSW	5	90,381,807 (GRCm39)	missense	possibly damaging	0.85
R7610:Ankrd17	UTSW	5	90,380,222 (GRCm39)	missense	possibly damaging	0.93
R7636:Ankrd17	UTSW	5	90,380,239 (GRCm39)	missense	possibly damaging	0.53
R7790:Ankrd17	UTSW	5	90,408,011 (GRCm39)	missense	possibly damaging	0.61
R7839:Ankrd17	UTSW	5	90,411,213 (GRCm39)	missense	probably damaging	0.97
R7853:Ankrd17	UTSW	5	90,386,825 (GRCm39)	missense	possibly damaging	0.91
R7976:Ankrd17	UTSW	5	90,431,451 (GRCm39)	nonsense	probably null
R8054:Ankrd17	UTSW	5	90,438,914 (GRCm39)	missense	probably benign	0.43
R8230:Ankrd17	UTSW	5	90,391,835 (GRCm39)	missense	possibly damaging	0.86
R8274:Ankrd17	UTSW	5	90,430,718 (GRCm39)	missense	probably benign	0.15
R8365:Ankrd17	UTSW	5	90,398,378 (GRCm39)	missense	possibly damaging	0.95
R8532:Ankrd17	UTSW	5	90,412,679 (GRCm39)	missense	probably damaging	1.00
R8729:Ankrd17	UTSW	5	90,443,452 (GRCm39)	missense	probably benign
R8812:Ankrd17	UTSW	5	90,441,062 (GRCm39)	missense	probably benign	0.09
R8933:Ankrd17	UTSW	5	90,406,325 (GRCm39)	missense	probably damaging	0.99
R9051:Ankrd17	UTSW	5	90,411,134 (GRCm39)	missense	probably damaging	0.99
R9055:Ankrd17	UTSW	5	90,380,168 (GRCm39)	missense	probably benign	0.33
R9136:Ankrd17	UTSW	5	90,392,278 (GRCm39)	missense	probably damaging	0.96
R9158:Ankrd17	UTSW	5	90,416,575 (GRCm39)	missense	probably damaging	1.00
R9201:Ankrd17	UTSW	5	90,378,798 (GRCm39)	missense	possibly damaging	0.84
R9315:Ankrd17	UTSW	5	90,398,360 (GRCm39)	missense	probably damaging	0.97
R9364:Ankrd17	UTSW	5	90,416,508 (GRCm39)	missense	probably damaging	1.00
R9366:Ankrd17	UTSW	5	90,416,508 (GRCm39)	missense	probably damaging	1.00
R9368:Ankrd17	UTSW	5	90,416,508 (GRCm39)	missense	probably damaging	1.00
R9368:Ankrd17	UTSW	5	90,391,986 (GRCm39)	missense	possibly damaging	0.91
R9369:Ankrd17	UTSW	5	90,416,508 (GRCm39)	missense	probably damaging	1.00
R9381:Ankrd17	UTSW	5	90,416,508 (GRCm39)	missense	probably damaging	1.00
R9570:Ankrd17	UTSW	5	90,401,536 (GRCm39)	missense
X0019:Ankrd17	UTSW	5	90,446,513 (GRCm39)	missense	probably damaging	1.00
Z1177:Ankrd17	UTSW	5	90,437,184 (GRCm39)	missense	possibly damaging	0.86
Z1177:Ankrd17	UTSW	5	90,431,364 (GRCm39)	missense	possibly damaging	0.83

Predicted Primers

PCR Primer
(F):5'- ATAGACTGGTGCACACTCCAC -3'
(R):5'- GTGCCTTAGGTCATGCATCC -3'

Sequencing Primer
(F):5'- GTGCACACTCCACCGACTTG -3'
(R):5'- GGTCATGCATCCAAGAACATATGGC -3'

Posted On

2019-10-07