Mutagenetix > Incidental Mutation

Incidental Mutation 'R7513:Igfn1'

582190

Institutional Source

Beutler Lab

Gene Symbol

Igfn1

Ensembl Gene

ENSMUSG00000051985

Gene Name

immunoglobulin-like and fibronectin type III domain containing 1

Synonyms

9830123M21Rik

MMRRC Submission

045586-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.099) question?

Stock #

R7513 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

135881316-135934080 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to G at 135887705 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Alanine at position 2453 (D2453A)

Ref Sequence

ENSEMBL: ENSMUSP00000129680 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000166193]

AlphaFold

no structure available at present

Predicted Effect

SMART Domains

Protein: ENSMUSP00000119230
Gene: ENSMUSG00000051985
AA Change: D837A

Domain	Start	End	E-Value	Type
IG	73	159	1.29e-6	SMART
IG_like	258	344	5.45e1	SMART
IG	354	435	1.79e0	SMART
IG	445	524	3.54e-4	SMART
IG	538	624	4.86e-2	SMART
FN3	627	711	3.99e-10	SMART
FN3	727	810	9.1e-14	SMART
FN3	828	911	1.5e-14	SMART
IG	938	1021	6.41e-2	SMART
FN3	1024	1106	3.2e-9	SMART
IGc2	1152	1219	4.89e-7	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000166193
AA Change: D2453A

PolyPhen 2 Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000129680
Gene: ENSMUSG00000051985
AA Change: D2453A

Domain	Start	End	E-Value	Type
low complexity region	90	101	N/A	INTRINSIC
IG	193	279	1.29e-6	SMART
PDB:2LHU\|A	302	365	8e-7	PDB
IG_like	378	464	5.45e1	SMART
IG	474	555	1.79e0	SMART
low complexity region	724	739	N/A	INTRINSIC
internal_repeat_2	838	1006	9.98e-5	PROSPERO
low complexity region	1067	1084	N/A	INTRINSIC
internal_repeat_2	1812	1967	9.98e-5	PROSPERO
Pfam:I-set	2054	2139	6.2e-8	PFAM
IG	2153	2239	4.86e-2	SMART
FN3	2242	2326	3.99e-10	SMART
FN3	2342	2425	9.1e-14	SMART
FN3	2443	2526	1.5e-14	SMART
IG	2553	2636	6.41e-2	SMART
FN3	2639	2721	3.2e-9	SMART
IGc2	2767	2834	4.89e-7	SMART

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.6%
20x: 98.7%

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 79 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcb1a	G	A	5: 8,765,771 (GRCm39)	W694*	probably null	Het
Accs	T	C	2: 93,670,437 (GRCm39)	N256S	possibly damaging	Het
Agmo	C	T	12: 37,294,352 (GRCm39)	T100I	probably benign	Het
Alox8	T	C	11: 69,078,670 (GRCm39)	D341G	probably benign	Het
Apol7c	T	A	15: 77,409,911 (GRCm39)	E345V	possibly damaging	Het
Arl5a	A	G	2: 52,302,157 (GRCm39)	F86L	possibly damaging	Het
AU040320	A	G	4: 126,686,057 (GRCm39)	E211G	probably benign	Het
B020011L13Rik	T	A	1: 117,729,149 (GRCm39)	C219S	probably damaging	Het
Btaf1	T	A	19: 36,955,803 (GRCm39)	L579Q	probably benign	Het
Cd84	T	A	1: 171,712,185 (GRCm39)	V267E	probably benign	Het
Cdcp3	G	A	7: 130,873,800 (GRCm39)	G1709R	unknown	Het
Clec11a	T	C	7: 43,955,780 (GRCm39)	E89G	probably benign	Het
Csrnp2	C	A	15: 100,380,297 (GRCm39)	E331D	probably benign	Het
Cyp2d12	C	A	15: 82,442,621 (GRCm39)	H355N	probably benign	Het
Ddx24	C	A	12: 103,385,365 (GRCm39)	G413*	probably null	Het
Dhx38	G	A	8: 110,287,221 (GRCm39)	P249L	probably benign	Het
Dip2a	A	T	10: 76,149,069 (GRCm39)	M233K	probably benign	Het
Dip2b	T	A	15: 100,105,629 (GRCm39)		probably null	Het
Dmbt1	T	C	7: 130,692,242 (GRCm39)	S1003P	unknown	Het
Dna2	A	G	10: 62,807,747 (GRCm39)	D1033G	probably benign	Het
Dnah5	T	C	15: 28,370,561 (GRCm39)	S2834P	probably benign	Het
Dnah7b	T	G	1: 46,163,506 (GRCm39)	S437A	probably benign	Het
Eif5	A	T	12: 111,506,686 (GRCm39)	I93F	probably damaging	Het
Fbxo47	A	G	11: 97,747,055 (GRCm39)	F337S	probably damaging	Het
Helz	T	C	11: 107,546,941 (GRCm39)	I1086T	probably damaging	Het
Ifi208	A	T	1: 173,523,220 (GRCm39)	R497*	probably null	Het
Ighg2c	A	T	12: 113,252,471 (GRCm39)	L27Q		Het
Jak1	C	T	4: 101,048,848 (GRCm39)	C10Y	probably damaging	Het
Kif7	T	A	7: 79,360,776 (GRCm39)	N200Y	possibly damaging	Het
Ktn1	G	C	14: 47,901,541 (GRCm39)	A100P	possibly damaging	Het
Lrsam1	T	C	2: 32,843,497 (GRCm39)	D136G	probably benign	Het
Man2c1	T	C	9: 57,046,683 (GRCm39)	L648P	probably benign	Het
Mki67	T	C	7: 135,294,952 (GRCm39)	I3116V	probably benign	Het
Mmp10	A	T	9: 7,508,128 (GRCm39)	D418V	probably damaging	Het
Mrpl24	A	T	3: 87,829,734 (GRCm39)	T107S	probably benign	Het
Mycbpap	T	A	11: 94,394,382 (GRCm39)	D296V	probably damaging	Het
Mycn	C	A	12: 12,989,743 (GRCm39)	A218S	probably benign	Het
Myo1f	G	T	17: 33,794,788 (GRCm39)	W9C	probably damaging	Het
Nckap1	T	A	2: 80,332,635 (GRCm39)	K1074N	possibly damaging	Het
Neb	T	C	2: 52,099,552 (GRCm39)	D4766G	possibly damaging	Het
Nhsl1	T	C	10: 18,399,700 (GRCm39)	S275P	probably damaging	Het
Or2d3c	A	G	7: 106,526,483 (GRCm39)	F61S	possibly damaging	Het
Or5k16	T	A	16: 58,736,295 (GRCm39)	K236N	probably damaging	Het
Pam	G	A	1: 97,780,910 (GRCm39)	P514S	possibly damaging	Het
Pcdha4	C	T	18: 37,086,392 (GRCm39)	L192F	probably damaging	Het
Per1	T	A	11: 68,996,397 (GRCm39)	D800E	probably benign	Het
Plcg2	C	A	8: 118,306,592 (GRCm39)	N315K	probably damaging	Het
Plxnb2	T	A	15: 89,042,525 (GRCm39)		probably null	Het
Pnpla1	A	G	17: 29,077,781 (GRCm39)		probably benign	Het
Pptc7	A	T	5: 122,446,192 (GRCm39)		probably null	Het
Psg26	G	T	7: 18,209,225 (GRCm39)	S394R	probably benign	Het
Psmc1	C	A	12: 100,081,773 (GRCm39)	T125K	probably benign	Het
Ptgis	T	A	2: 167,067,203 (GRCm39)	M125L	probably benign	Het
Rbms1	A	G	2: 60,589,165 (GRCm39)	Y323H	probably damaging	Het
Rgl2	G	A	17: 34,151,529 (GRCm39)	R191Q	probably benign	Het
Sirpb1a	G	A	3: 15,476,503 (GRCm39)	T98I	possibly damaging	Het
Sirpb1b	C	A	3: 15,607,200 (GRCm39)	E361*	probably null	Het
Slc13a4	A	T	6: 35,260,272 (GRCm39)		probably null	Het
Spag9	T	C	11: 94,002,909 (GRCm39)	S1140P	probably damaging	Het
Spata31e4	T	A	13: 50,856,909 (GRCm39)	I849N	probably benign	Het
Tas2r140	A	G	6: 40,469,084 (GRCm39)	N305D	probably damaging	Het
Tenm2	G	A	11: 35,942,727 (GRCm39)	A1314V	probably benign	Het
Tgm3	A	G	2: 129,866,324 (GRCm39)	T81A	probably benign	Het
Timeless	T	C	10: 128,085,399 (GRCm39)	V839A	probably damaging	Het
Tmem132a	A	G	19: 10,837,492 (GRCm39)	I606T	probably damaging	Het
Tox	T	A	4: 6,741,507 (GRCm39)	M158L	probably benign	Het
Trpc2	A	T	7: 101,739,275 (GRCm39)	M549L	probably damaging	Het
Trpm5	C	T	7: 142,635,572 (GRCm39)	R600Q	possibly damaging	Het
Trpv1	A	G	11: 73,131,367 (GRCm39)	N302D	probably damaging	Het
Ttn	C	T	2: 76,681,940 (GRCm39)	R1019H		Het
Ttn	G	T	2: 76,775,307 (GRCm39)	H1958N	unknown	Het
Usp32	A	T	11: 84,917,938 (GRCm39)	Y769*	probably null	Het
Vim	A	T	2: 13,583,443 (GRCm39)	Q255L	possibly damaging	Het
Vmn1r84	T	C	7: 12,095,994 (GRCm39)	H233R	probably benign	Het
Xirp2	T	A	2: 67,341,108 (GRCm39)	H1116Q	possibly damaging	Het
Zc3h18	G	T	8: 123,134,993 (GRCm39)	R580L	unknown	Het
Zfp267	T	A	3: 36,218,792 (GRCm39)	F272I	possibly damaging	Het
Zfp442	A	T	2: 150,250,676 (GRCm39)	C409S	unknown	Het
Zfy1	A	T	Y: 759,852 (GRCm39)	I20K	unknown	Het

Other mutations in Igfn1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00753:Igfn1	APN	1	135,894,464 (GRCm39)	missense	probably damaging	1.00
IGL02299:Igfn1	APN	1	135,881,755 (GRCm39)	utr 3 prime	probably benign
Bounty	UTSW	1	135,904,655 (GRCm39)	critical splice donor site	probably null
R2276_Igfn1_773	UTSW	1	135,892,479 (GRCm39)	missense	probably damaging	0.98
R4058_Igfn1_315	UTSW	1	135,897,494 (GRCm39)	missense	probably benign	0.07
R0144:Igfn1	UTSW	1	135,889,751 (GRCm39)	missense	probably damaging	0.99
R0190:Igfn1	UTSW	1	135,889,790 (GRCm39)	missense	probably damaging	1.00
R0350:Igfn1	UTSW	1	135,884,505 (GRCm39)	nonsense	probably null
R0413:Igfn1	UTSW	1	135,895,334 (GRCm39)	missense	probably benign	0.23
R0504:Igfn1	UTSW	1	135,896,267 (GRCm39)	missense	probably benign	0.00
R0606:Igfn1	UTSW	1	135,887,639 (GRCm39)	missense	probably damaging	1.00
R0681:Igfn1	UTSW	1	135,891,591 (GRCm39)	missense	possibly damaging	0.88
R0825:Igfn1	UTSW	1	135,890,864 (GRCm39)	missense	probably damaging	1.00
R0839:Igfn1	UTSW	1	135,882,418 (GRCm39)	missense	probably damaging	1.00
R1066:Igfn1	UTSW	1	135,898,463 (GRCm39)	missense	probably benign
R1078:Igfn1	UTSW	1	135,902,585 (GRCm39)	missense	probably damaging	1.00
R1224:Igfn1	UTSW	1	135,897,494 (GRCm39)	missense	probably benign	0.07
R1569:Igfn1	UTSW	1	135,896,771 (GRCm39)	missense	probably benign
R1626:Igfn1	UTSW	1	135,896,705 (GRCm39)	missense	probably benign	0.29
R1663:Igfn1	UTSW	1	135,896,046 (GRCm39)	missense	probably benign	0.15
R1677:Igfn1	UTSW	1	135,898,839 (GRCm39)	missense	probably damaging	0.99
R1709:Igfn1	UTSW	1	135,883,311 (GRCm39)	missense	probably benign	0.24
R1728:Igfn1	UTSW	1	135,926,421 (GRCm39)	missense	unknown
R1728:Igfn1	UTSW	1	135,926,363 (GRCm39)	missense	probably benign
R1728:Igfn1	UTSW	1	135,910,213 (GRCm39)	missense	probably benign
R1728:Igfn1	UTSW	1	135,907,653 (GRCm39)	missense	probably benign	0.00
R1728:Igfn1	UTSW	1	135,899,865 (GRCm39)	missense	probably benign
R1728:Igfn1	UTSW	1	135,898,149 (GRCm39)	missense	probably benign
R1728:Igfn1	UTSW	1	135,895,937 (GRCm39)	missense	probably benign
R1728:Igfn1	UTSW	1	135,887,666 (GRCm39)	missense	probably damaging	1.00
R1729:Igfn1	UTSW	1	135,910,213 (GRCm39)	missense	probably benign
R1729:Igfn1	UTSW	1	135,907,653 (GRCm39)	missense	probably benign	0.00
R1729:Igfn1	UTSW	1	135,899,865 (GRCm39)	missense	probably benign
R1729:Igfn1	UTSW	1	135,898,149 (GRCm39)	missense	probably benign
R1729:Igfn1	UTSW	1	135,895,937 (GRCm39)	missense	probably benign
R1729:Igfn1	UTSW	1	135,887,666 (GRCm39)	missense	probably damaging	1.00
R1729:Igfn1	UTSW	1	135,926,421 (GRCm39)	missense	unknown
R1729:Igfn1	UTSW	1	135,926,363 (GRCm39)	missense	probably benign
R1730:Igfn1	UTSW	1	135,887,666 (GRCm39)	missense	probably damaging	1.00
R1730:Igfn1	UTSW	1	135,895,937 (GRCm39)	missense	probably benign
R1730:Igfn1	UTSW	1	135,898,149 (GRCm39)	missense	probably benign
R1730:Igfn1	UTSW	1	135,899,865 (GRCm39)	missense	probably benign
R1730:Igfn1	UTSW	1	135,907,653 (GRCm39)	missense	probably benign	0.00
R1730:Igfn1	UTSW	1	135,910,213 (GRCm39)	missense	probably benign
R1730:Igfn1	UTSW	1	135,926,363 (GRCm39)	missense	probably benign
R1730:Igfn1	UTSW	1	135,926,421 (GRCm39)	missense	unknown
R1739:Igfn1	UTSW	1	135,899,865 (GRCm39)	missense	probably benign
R1739:Igfn1	UTSW	1	135,907,653 (GRCm39)	missense	probably benign	0.00
R1739:Igfn1	UTSW	1	135,910,213 (GRCm39)	missense	probably benign
R1739:Igfn1	UTSW	1	135,926,363 (GRCm39)	missense	probably benign
R1739:Igfn1	UTSW	1	135,898,149 (GRCm39)	missense	probably benign
R1739:Igfn1	UTSW	1	135,895,937 (GRCm39)	missense	probably benign
R1739:Igfn1	UTSW	1	135,887,666 (GRCm39)	missense	probably damaging	1.00
R1739:Igfn1	UTSW	1	135,926,421 (GRCm39)	missense	unknown
R1746:Igfn1	UTSW	1	135,897,561 (GRCm39)	missense	possibly damaging	0.88
R1762:Igfn1	UTSW	1	135,926,363 (GRCm39)	missense	probably benign
R1762:Igfn1	UTSW	1	135,910,213 (GRCm39)	missense	probably benign
R1762:Igfn1	UTSW	1	135,907,653 (GRCm39)	missense	probably benign	0.00
R1762:Igfn1	UTSW	1	135,899,865 (GRCm39)	missense	probably benign
R1762:Igfn1	UTSW	1	135,898,149 (GRCm39)	missense	probably benign
R1762:Igfn1	UTSW	1	135,895,937 (GRCm39)	missense	probably benign
R1762:Igfn1	UTSW	1	135,887,666 (GRCm39)	missense	probably damaging	1.00
R1762:Igfn1	UTSW	1	135,926,421 (GRCm39)	missense	unknown
R1783:Igfn1	UTSW	1	135,910,213 (GRCm39)	missense	probably benign
R1783:Igfn1	UTSW	1	135,907,653 (GRCm39)	missense	probably benign	0.00
R1783:Igfn1	UTSW	1	135,899,865 (GRCm39)	missense	probably benign
R1783:Igfn1	UTSW	1	135,898,149 (GRCm39)	missense	probably benign
R1783:Igfn1	UTSW	1	135,895,937 (GRCm39)	missense	probably benign
R1783:Igfn1	UTSW	1	135,887,666 (GRCm39)	missense	probably damaging	1.00
R1783:Igfn1	UTSW	1	135,926,421 (GRCm39)	missense	unknown
R1783:Igfn1	UTSW	1	135,926,363 (GRCm39)	missense	probably benign
R1784:Igfn1	UTSW	1	135,926,421 (GRCm39)	missense	unknown
R1784:Igfn1	UTSW	1	135,926,363 (GRCm39)	missense	probably benign
R1784:Igfn1	UTSW	1	135,910,213 (GRCm39)	missense	probably benign
R1784:Igfn1	UTSW	1	135,907,653 (GRCm39)	missense	probably benign	0.00
R1784:Igfn1	UTSW	1	135,899,865 (GRCm39)	missense	probably benign
R1784:Igfn1	UTSW	1	135,898,149 (GRCm39)	missense	probably benign
R1784:Igfn1	UTSW	1	135,895,937 (GRCm39)	missense	probably benign
R1784:Igfn1	UTSW	1	135,887,666 (GRCm39)	missense	probably damaging	1.00
R1785:Igfn1	UTSW	1	135,926,421 (GRCm39)	missense	unknown
R1785:Igfn1	UTSW	1	135,926,363 (GRCm39)	missense	probably benign
R1785:Igfn1	UTSW	1	135,910,213 (GRCm39)	missense	probably benign
R1785:Igfn1	UTSW	1	135,907,653 (GRCm39)	missense	probably benign	0.00
R1785:Igfn1	UTSW	1	135,899,865 (GRCm39)	missense	probably benign
R1785:Igfn1	UTSW	1	135,898,149 (GRCm39)	missense	probably benign
R1785:Igfn1	UTSW	1	135,895,937 (GRCm39)	missense	probably benign
R1785:Igfn1	UTSW	1	135,887,666 (GRCm39)	missense	probably damaging	1.00
R1847:Igfn1	UTSW	1	135,897,126 (GRCm39)	missense	probably benign
R1866:Igfn1	UTSW	1	135,902,606 (GRCm39)	splice site	probably null
R1921:Igfn1	UTSW	1	135,893,801 (GRCm39)	critical splice donor site	probably null
R1984:Igfn1	UTSW	1	135,889,782 (GRCm39)	missense	probably benign	0.39
R2049:Igfn1	UTSW	1	135,902,590 (GRCm39)	splice site	probably benign
R2049:Igfn1	UTSW	1	135,898,376 (GRCm39)	missense	probably benign
R2098:Igfn1	UTSW	1	135,906,043 (GRCm39)	missense	probably damaging	1.00
R2130:Igfn1	UTSW	1	135,902,590 (GRCm39)	splice site	probably benign
R2141:Igfn1	UTSW	1	135,902,590 (GRCm39)	splice site	probably benign
R2276:Igfn1	UTSW	1	135,892,479 (GRCm39)	missense	probably damaging	0.98
R2425:Igfn1	UTSW	1	135,890,840 (GRCm39)	missense	probably damaging	1.00
R2483:Igfn1	UTSW	1	135,897,275 (GRCm39)	missense	probably benign
R2504:Igfn1	UTSW	1	135,897,054 (GRCm39)	missense	probably benign	0.07
R3109:Igfn1	UTSW	1	135,925,586 (GRCm39)	missense	probably benign	0.12
R3421:Igfn1	UTSW	1	135,904,655 (GRCm39)	critical splice donor site	probably null
R3423:Igfn1	UTSW	1	135,926,379 (GRCm39)	missense	probably benign	0.01
R3705:Igfn1	UTSW	1	135,896,147 (GRCm39)	missense	probably benign
R3871:Igfn1	UTSW	1	135,896,574 (GRCm39)	missense	probably benign	0.03
R3875:Igfn1	UTSW	1	135,882,352 (GRCm39)	missense	probably damaging	1.00
R3953:Igfn1	UTSW	1	135,894,918 (GRCm39)	missense	possibly damaging	0.61
R3955:Igfn1	UTSW	1	135,894,918 (GRCm39)	missense	possibly damaging	0.61
R3957:Igfn1	UTSW	1	135,894,918 (GRCm39)	missense	possibly damaging	0.61
R3965:Igfn1	UTSW	1	135,895,557 (GRCm39)	missense	probably benign
R4006:Igfn1	UTSW	1	135,910,100 (GRCm39)	splice site	probably null
R4058:Igfn1	UTSW	1	135,897,494 (GRCm39)	missense	probably benign	0.07
R4059:Igfn1	UTSW	1	135,897,494 (GRCm39)	missense	probably benign	0.07
R4370:Igfn1	UTSW	1	135,895,844 (GRCm39)	missense	probably benign	0.00
R4380:Igfn1	UTSW	1	135,895,509 (GRCm39)	missense	probably benign	0.00
R4495:Igfn1	UTSW	1	135,897,416 (GRCm39)	missense	possibly damaging	0.79
R4628:Igfn1	UTSW	1	135,887,468 (GRCm39)	missense	possibly damaging	0.47
R4672:Igfn1	UTSW	1	135,893,107 (GRCm39)	missense	possibly damaging	0.72
R4682:Igfn1	UTSW	1	135,926,363 (GRCm39)	missense	probably benign
R4702:Igfn1	UTSW	1	135,894,947 (GRCm39)	missense	possibly damaging	0.71
R4744:Igfn1	UTSW	1	135,910,196 (GRCm39)	missense	probably benign	0.07
R4777:Igfn1	UTSW	1	135,882,600 (GRCm39)	missense	probably benign
R4806:Igfn1	UTSW	1	135,895,095 (GRCm39)	missense	probably benign	0.01
R4840:Igfn1	UTSW	1	135,895,778 (GRCm39)	missense	probably benign	0.00
R4894:Igfn1	UTSW	1	135,882,520 (GRCm39)	missense	probably damaging	1.00
R4998:Igfn1	UTSW	1	135,882,404 (GRCm39)	missense	probably damaging	1.00
R5092:Igfn1	UTSW	1	135,892,564 (GRCm39)	missense	probably benign
R5108:Igfn1	UTSW	1	135,910,179 (GRCm39)	missense	probably benign
R5120:Igfn1	UTSW	1	135,901,240 (GRCm39)	missense	possibly damaging	0.93
R5127:Igfn1	UTSW	1	135,887,634 (GRCm39)	missense	probably damaging	1.00
R5231:Igfn1	UTSW	1	135,894,474 (GRCm39)	missense	probably benign	0.26
R5286:Igfn1	UTSW	1	135,895,599 (GRCm39)	missense	probably benign	0.10
R5307:Igfn1	UTSW	1	135,892,676 (GRCm39)	missense	probably damaging	1.00
R5380:Igfn1	UTSW	1	135,893,825 (GRCm39)	missense	probably damaging	1.00
R5553:Igfn1	UTSW	1	135,895,622 (GRCm39)	missense	probably damaging	1.00
R5660:Igfn1	UTSW	1	135,898,152 (GRCm39)	missense	probably benign	0.01
R5779:Igfn1	UTSW	1	135,894,578 (GRCm39)	missense	probably benign	0.16
R5818:Igfn1	UTSW	1	135,893,864 (GRCm39)	missense	possibly damaging	0.72
R5832:Igfn1	UTSW	1	135,902,533 (GRCm39)	missense	probably damaging	0.96
R5933:Igfn1	UTSW	1	135,898,341 (GRCm39)	nonsense	probably null
R5966:Igfn1	UTSW	1	135,893,152 (GRCm39)	missense	probably damaging	1.00
R6116:Igfn1	UTSW	1	135,898,205 (GRCm39)	missense	probably benign	0.00
R6297:Igfn1	UTSW	1	135,892,399 (GRCm39)	critical splice donor site	probably null
R6652:Igfn1	UTSW	1	135,891,609 (GRCm39)	missense	probably damaging	1.00
R6737:Igfn1	UTSW	1	135,897,605 (GRCm39)	missense	probably benign
R6816:Igfn1	UTSW	1	135,887,466 (GRCm39)	missense	probably benign	0.02
R6886:Igfn1	UTSW	1	135,901,198 (GRCm39)	missense	probably damaging	1.00
R6888:Igfn1	UTSW	1	135,910,218 (GRCm39)	missense	probably benign	0.33
R6975:Igfn1	UTSW	1	135,896,183 (GRCm39)	missense	probably damaging	0.96
R7105:Igfn1	UTSW	1	135,911,956 (GRCm39)	missense	probably benign	0.11
R7114:Igfn1	UTSW	1	135,894,519 (GRCm39)	missense	probably benign	0.01
R7233:Igfn1	UTSW	1	135,897,873 (GRCm39)	missense	probably benign	0.41
R7276:Igfn1	UTSW	1	135,926,376 (GRCm39)	missense	possibly damaging	0.85
R7354:Igfn1	UTSW	1	135,903,770 (GRCm39)	missense	possibly damaging	0.72
R7358:Igfn1	UTSW	1	135,891,738 (GRCm39)	missense	probably damaging	1.00
R7380:Igfn1	UTSW	1	135,889,746 (GRCm39)	missense	probably damaging	1.00
R7389:Igfn1	UTSW	1	135,894,785 (GRCm39)	missense	probably benign	0.00
R7718:Igfn1	UTSW	1	135,896,774 (GRCm39)	missense	probably benign
R7769:Igfn1	UTSW	1	135,910,143 (GRCm39)	missense	possibly damaging	0.85
R7810:Igfn1	UTSW	1	135,902,527 (GRCm39)	missense	probably damaging	0.98
R7917:Igfn1	UTSW	1	135,899,706 (GRCm39)	missense	probably damaging	0.99
R7952:Igfn1	UTSW	1	135,891,693 (GRCm39)	missense	probably damaging	0.99
R8041:Igfn1	UTSW	1	135,895,797 (GRCm39)	nonsense	probably null
R8233:Igfn1	UTSW	1	135,895,782 (GRCm39)	missense	probably benign	0.00
R8354:Igfn1	UTSW	1	135,887,619 (GRCm39)	missense	possibly damaging	0.61
R8363:Igfn1	UTSW	1	135,891,625 (GRCm39)	missense	probably benign	0.01
R8428:Igfn1	UTSW	1	135,895,520 (GRCm39)	missense	probably damaging	1.00
R8731:Igfn1	UTSW	1	135,925,574 (GRCm39)	missense	probably benign	0.02
R8756:Igfn1	UTSW	1	135,895,698 (GRCm39)	missense	probably benign	0.10
R8797:Igfn1	UTSW	1	135,902,573 (GRCm39)	missense	possibly damaging	0.93
R8913:Igfn1	UTSW	1	135,891,579 (GRCm39)	missense	possibly damaging	0.90
R8927:Igfn1	UTSW	1	135,905,984 (GRCm39)	missense	probably damaging	1.00
R8928:Igfn1	UTSW	1	135,905,984 (GRCm39)	missense	probably damaging	1.00
R9087:Igfn1	UTSW	1	135,902,606 (GRCm39)	splice site	probably null
R9109:Igfn1	UTSW	1	135,926,327 (GRCm39)	missense	probably benign	0.26
R9113:Igfn1	UTSW	1	135,883,328 (GRCm39)	missense	probably damaging	1.00
R9117:Igfn1	UTSW	1	135,902,528 (GRCm39)	missense	probably benign	0.03
R9205:Igfn1	UTSW	1	135,903,695 (GRCm39)	missense	probably damaging	0.96
R9251:Igfn1	UTSW	1	135,894,409 (GRCm39)	splice site	probably benign
R9260:Igfn1	UTSW	1	135,907,694 (GRCm39)	missense	probably benign	0.45
R9275:Igfn1	UTSW	1	135,901,185 (GRCm39)	missense	probably damaging	0.96
R9277:Igfn1	UTSW	1	135,887,520 (GRCm39)	missense	probably damaging	0.98
R9278:Igfn1	UTSW	1	135,901,185 (GRCm39)	missense	probably damaging	0.96
R9287:Igfn1	UTSW	1	135,925,544 (GRCm39)	missense	probably benign	0.33
R9298:Igfn1	UTSW	1	135,926,327 (GRCm39)	missense	probably benign	0.26
R9356:Igfn1	UTSW	1	135,899,825 (GRCm39)	nonsense	probably null
R9371:Igfn1	UTSW	1	135,906,001 (GRCm39)	missense	probably damaging	1.00
R9532:Igfn1	UTSW	1	135,897,229 (GRCm39)	missense	possibly damaging	0.61
R9653:Igfn1	UTSW	1	135,883,323 (GRCm39)	nonsense	probably null
R9666:Igfn1	UTSW	1	135,897,692 (GRCm39)	missense	possibly damaging	0.65
R9741:Igfn1	UTSW	1	135,895,383 (GRCm39)	missense	probably benign	0.00
R9748:Igfn1	UTSW	1	135,926,336 (GRCm39)	missense	possibly damaging	0.89
R9796:Igfn1	UTSW	1	135,897,611 (GRCm39)	missense	probably benign	0.26
Z1176:Igfn1	UTSW	1	135,899,738 (GRCm39)	missense	probably damaging	0.99
Z1177:Igfn1	UTSW	1	135,897,305 (GRCm39)	missense	probably benign	0.26
Z1177:Igfn1	UTSW	1	135,883,547 (GRCm39)	missense	probably damaging	1.00
Z1177:Igfn1	UTSW	1	135,910,164 (GRCm39)	missense	possibly damaging	0.73

Predicted Primers

PCR Primer
(F):5'- ACAAAGTAGCCTTCTTGCGG -3'
(R):5'- ACCAGCTGTCAAGGATTATGGG -3'

Sequencing Primer
(F):5'- CTTCTTGCGGCCGAAGC -3'
(R):5'- GCTGTCAAGGATTATGGGATAGTTAG -3'

Posted On

2019-10-17