Incidental Mutation 'R7514:Myh4'
| ID |
582327 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myh4
|
| Ensembl Gene |
ENSMUSG00000057003 |
| Gene Name |
myosin, heavy polypeptide 4, skeletal muscle |
| Synonyms |
MYH-2B, MM, MHC2B, MyHC-IIb, Myhsf, Minimsc, Minmus |
| MMRRC Submission |
045587-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.386)
|
| Stock # |
R7514 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
11 |
| Chromosomal Location |
67128855-67151272 bp(+) (GRCm39) |
| Type of Mutation |
critical splice donor site (1 bp from exon) |
| DNA Base Change (assembly) |
G to A
at 67134148 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000127514
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000018632]
[ENSMUST00000170942]
|
| AlphaFold |
Q5SX39 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000018632
|
| SMART Domains |
Protein: ENSMUSP00000018632
Gene: ENSMUSG00000057003
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Myosin_N
|
35 |
74 |
4.7e-14 |
PFAM |
|
MYSc
|
80 |
783 |
N/A |
SMART |
|
IQ
|
784 |
806 |
8.84e-3 |
SMART |
|
Pfam:Myosin_tail_1
|
847 |
1928 |
2.5e-168 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000170942
|
| SMART Domains |
Protein: ENSMUSP00000127514
Gene: ENSMUSG00000057003
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Myosin_N
|
35 |
76 |
1.1e-15 |
PFAM |
|
MYSc
|
80 |
783 |
N/A |
SMART |
|
IQ
|
784 |
806 |
8.84e-3 |
SMART |
|
low complexity region
|
928 |
942 |
N/A |
INTRINSIC |
|
Pfam:Myosin_tail_1
|
1072 |
1930 |
N/A |
PFAM |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.4%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Homozygotes for a targeted null mutation exhibit decreased growth and muscle defects including reduced muscle mass, muscle fiber loss, compensatory fiber hypertrophy, and impaired strength. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(3) : Targeted, knock-out(1) Targeted, other(2) |
| Other mutations in this stock |
Total: 103 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933427D14Rik |
A |
G |
11: 72,086,628 (GRCm39) |
L261P |
probably damaging |
Het |
| A4gnt |
A |
G |
9: 99,502,598 (GRCm39) |
I253V |
probably benign |
Het |
| AAdacl4fm3 |
A |
T |
4: 144,429,798 (GRCm39) |
V397D |
possibly damaging |
Het |
| Acap2 |
A |
T |
16: 30,973,385 (GRCm39) |
|
probably null |
Het |
| Adora2b |
G |
T |
11: 62,156,146 (GRCm39) |
M198I |
probably damaging |
Het |
| Akap5 |
C |
A |
12: 76,375,303 (GRCm39) |
T245K |
probably benign |
Het |
| Aldh1a2 |
T |
C |
9: 71,192,245 (GRCm39) |
I399T |
probably damaging |
Het |
| Ank2 |
G |
A |
3: 126,819,252 (GRCm39) |
S473L |
probably benign |
Het |
| Anln |
A |
T |
9: 22,272,153 (GRCm39) |
D655E |
probably damaging |
Het |
| Arhgef10 |
T |
C |
8: 15,025,956 (GRCm39) |
V820A |
probably benign |
Het |
| Arid1b |
A |
G |
17: 5,391,989 (GRCm39) |
K1787E |
probably benign |
Het |
| Art4 |
T |
C |
6: 136,831,739 (GRCm39) |
H134R |
probably benign |
Het |
| Borcs6 |
G |
A |
11: 68,951,410 (GRCm39) |
V263M |
probably damaging |
Het |
| C8a |
A |
T |
4: 104,703,247 (GRCm39) |
M314K |
possibly damaging |
Het |
| Cbfa2t3 |
T |
G |
8: 123,361,865 (GRCm39) |
M386L |
probably damaging |
Het |
| Ccdc170 |
T |
A |
10: 4,496,839 (GRCm39) |
V459E |
probably benign |
Het |
| Cdh4 |
T |
A |
2: 179,532,636 (GRCm39) |
N699K |
possibly damaging |
Het |
| Cdk12 |
T |
C |
11: 98,113,484 (GRCm39) |
L756P |
unknown |
Het |
| Chsy1 |
A |
G |
7: 65,821,868 (GRCm39) |
D701G |
probably damaging |
Het |
| Cnot9 |
A |
G |
1: 74,567,921 (GRCm39) |
T270A |
probably benign |
Het |
| Crat |
C |
T |
2: 30,294,577 (GRCm39) |
R497Q |
probably benign |
Het |
| Csnk2a1-ps3 |
A |
G |
1: 156,352,324 (GRCm39) |
D175G |
probably benign |
Het |
| Cyb5r1 |
A |
G |
1: 134,338,268 (GRCm39) |
E228G |
probably damaging |
Het |
| D630003M21Rik |
A |
G |
2: 158,059,273 (GRCm39) |
L209P |
probably damaging |
Het |
| Dennd2c |
T |
A |
3: 103,070,378 (GRCm39) |
D791E |
probably benign |
Het |
| Dnah14 |
T |
C |
1: 181,455,632 (GRCm39) |
I919T |
probably damaging |
Het |
| Dpp8 |
T |
C |
9: 64,986,036 (GRCm39) |
L842S |
probably damaging |
Het |
| Ern1 |
A |
G |
11: 106,300,719 (GRCm39) |
|
probably null |
Het |
| Exo1 |
T |
C |
1: 175,734,232 (GRCm39) |
|
probably null |
Het |
| Fam161b |
T |
G |
12: 84,404,512 (GRCm39) |
E56A |
possibly damaging |
Het |
| Fbrsl1 |
T |
C |
5: 110,580,799 (GRCm39) |
T153A |
probably benign |
Het |
| Fcgr3 |
T |
G |
1: 170,886,912 (GRCm39) |
D4A |
probably benign |
Het |
| Gltp |
C |
T |
5: 114,808,521 (GRCm39) |
A193T |
probably benign |
Het |
| Gm3159 |
A |
T |
14: 4,399,690 (GRCm38) |
S142C |
probably damaging |
Het |
| Gphn |
T |
C |
12: 78,672,939 (GRCm39) |
V485A |
probably damaging |
Het |
| Grik2 |
A |
T |
10: 49,399,904 (GRCm39) |
N275K |
probably damaging |
Het |
| Gstt3 |
G |
T |
10: 75,612,625 (GRCm39) |
Q102K |
probably damaging |
Het |
| Hivep3 |
T |
A |
4: 119,954,052 (GRCm39) |
F789L |
possibly damaging |
Het |
| Ing5 |
A |
G |
1: 93,744,164 (GRCm39) |
N157D |
possibly damaging |
Het |
| Itga3 |
C |
T |
11: 94,956,722 (GRCm39) |
W177* |
probably null |
Het |
| Jag2 |
T |
C |
12: 112,892,672 (GRCm39) |
T83A |
probably benign |
Het |
| Krt90 |
G |
A |
15: 101,461,605 (GRCm39) |
T532I |
unknown |
Het |
| Lcn2 |
A |
G |
2: 32,277,861 (GRCm39) |
|
probably null |
Het |
| Lrig2 |
A |
G |
3: 104,373,076 (GRCm39) |
S602P |
probably damaging |
Het |
| Lsm1 |
A |
C |
8: 26,282,237 (GRCm39) |
R33S |
probably damaging |
Het |
| Mast4 |
A |
T |
13: 102,923,934 (GRCm39) |
Y492* |
probably null |
Het |
| Mcm3 |
A |
T |
1: 20,876,120 (GRCm39) |
L658Q |
probably benign |
Het |
| Nck2 |
T |
C |
1: 43,608,381 (GRCm39) |
V341A |
probably benign |
Het |
| Nucb1 |
T |
C |
7: 45,151,142 (GRCm39) |
|
probably null |
Het |
| Nup210l |
G |
C |
3: 90,117,766 (GRCm39) |
|
probably null |
Het |
| Or1j1 |
A |
G |
2: 36,702,651 (GRCm39) |
I151T |
probably benign |
Het |
| Or5al5 |
A |
T |
2: 85,961,972 (GRCm39) |
F12I |
probably damaging |
Het |
| Or7g22 |
A |
T |
9: 19,049,161 (GRCm39) |
S291C |
possibly damaging |
Het |
| Or8b48 |
T |
A |
9: 38,493,347 (GRCm39) |
M258K |
probably damaging |
Het |
| Or8b54 |
G |
A |
9: 38,686,974 (GRCm39) |
C141Y |
probably damaging |
Het |
| Pla2g4a |
G |
A |
1: 149,727,113 (GRCm39) |
P556S |
probably damaging |
Het |
| Plat |
T |
C |
8: 23,265,658 (GRCm39) |
C234R |
probably damaging |
Het |
| Ppfia1 |
T |
C |
7: 144,071,450 (GRCm39) |
I321V |
probably benign |
Het |
| Prrc1 |
T |
A |
18: 57,496,325 (GRCm39) |
V92E |
probably benign |
Het |
| Prss3 |
A |
G |
6: 41,350,848 (GRCm39) |
V214A |
probably damaging |
Het |
| Ptprg |
G |
T |
14: 12,179,342 (GRCm38) |
K786N |
possibly damaging |
Het |
| Rabgap1 |
G |
T |
2: 37,427,354 (GRCm39) |
G645V |
probably damaging |
Het |
| Rfx4 |
T |
C |
10: 84,716,090 (GRCm39) |
S470P |
probably damaging |
Het |
| Rin3 |
C |
T |
12: 102,335,909 (GRCm39) |
Q607* |
probably null |
Het |
| Sema3a |
A |
G |
5: 13,573,093 (GRCm39) |
H207R |
probably benign |
Het |
| Serpinb12 |
G |
A |
1: 106,878,534 (GRCm39) |
E181K |
probably damaging |
Het |
| Serpinb6c |
G |
A |
13: 34,081,386 (GRCm39) |
Q88* |
probably null |
Het |
| Shmt1 |
A |
C |
11: 60,692,812 (GRCm39) |
C90W |
probably damaging |
Het |
| Slc16a13 |
C |
T |
11: 70,109,710 (GRCm39) |
V264M |
probably damaging |
Het |
| Slc17a8 |
G |
T |
10: 89,427,969 (GRCm39) |
P286Q |
probably damaging |
Het |
| Slc27a6 |
C |
T |
18: 58,745,293 (GRCm39) |
Q576* |
probably null |
Het |
| Slc30a9 |
T |
C |
5: 67,505,421 (GRCm39) |
S470P |
possibly damaging |
Het |
| Slc44a2 |
G |
T |
9: 21,253,768 (GRCm39) |
K136N |
possibly damaging |
Het |
| Smarca5 |
A |
T |
8: 81,444,163 (GRCm39) |
H534Q |
probably damaging |
Het |
| Son |
T |
G |
16: 91,451,748 (GRCm39) |
L165R |
probably damaging |
Het |
| Sox10 |
G |
A |
15: 79,040,421 (GRCm39) |
P373L |
probably benign |
Het |
| Sp100 |
C |
T |
1: 85,608,860 (GRCm39) |
R330* |
probably null |
Het |
| Srrm4 |
A |
G |
5: 116,584,570 (GRCm39) |
L500P |
probably damaging |
Het |
| Tap1 |
T |
C |
17: 34,415,639 (GRCm39) |
L689P |
probably damaging |
Het |
| Tfg |
A |
G |
16: 56,525,972 (GRCm39) |
|
probably null |
Het |
| Tjp2 |
C |
T |
19: 24,088,886 (GRCm39) |
V677I |
probably benign |
Het |
| Tmprss11g |
T |
G |
5: 86,645,176 (GRCm39) |
D85A |
probably damaging |
Het |
| Tnfsf9 |
T |
C |
17: 57,414,238 (GRCm39) |
S222P |
probably damaging |
Het |
| Trank1 |
A |
G |
9: 111,193,824 (GRCm39) |
N616S |
probably damaging |
Het |
| Tubgcp6 |
C |
A |
15: 89,004,728 (GRCm39) |
W297L |
probably damaging |
Het |
| Twist1 |
T |
C |
12: 34,008,355 (GRCm39) |
S127P |
probably damaging |
Het |
| Ubr4 |
T |
C |
4: 139,179,966 (GRCm39) |
I247T |
unknown |
Het |
| Ubr5 |
G |
A |
15: 37,988,481 (GRCm39) |
T2153M |
|
Het |
| Utrn |
A |
G |
10: 12,573,833 (GRCm39) |
V1079A |
probably benign |
Het |
| Vcan |
T |
C |
13: 89,852,237 (GRCm39) |
T908A |
probably damaging |
Het |
| Vmn2r104 |
A |
G |
17: 20,249,791 (GRCm39) |
F827L |
probably damaging |
Het |
| Vmn2r111 |
T |
A |
17: 22,767,380 (GRCm39) |
T706S |
probably benign |
Het |
| Vmn2r114 |
T |
C |
17: 23,527,035 (GRCm39) |
D499G |
probably null |
Het |
| Vmn2r92 |
T |
C |
17: 18,391,533 (GRCm39) |
S512P |
probably damaging |
Het |
| Vps4b |
A |
T |
1: 106,708,232 (GRCm39) |
|
probably null |
Het |
| Vwa8 |
A |
C |
14: 79,219,674 (GRCm39) |
|
probably null |
Het |
| Wnt10b |
T |
C |
15: 98,672,045 (GRCm39) |
Q224R |
probably benign |
Het |
| Ylpm1 |
C |
T |
12: 85,077,268 (GRCm39) |
P1331L |
possibly damaging |
Het |
| Zfhx4 |
G |
A |
3: 5,307,267 (GRCm39) |
M164I |
possibly damaging |
Het |
| Zfp51 |
A |
G |
17: 21,683,762 (GRCm39) |
T126A |
probably benign |
Het |
| Zfp609 |
A |
G |
9: 65,613,418 (GRCm39) |
V339A |
probably benign |
Het |
| Zfp687 |
C |
T |
3: 94,914,841 (GRCm39) |
R1220H |
probably damaging |
Het |
| Zfyve21 |
C |
T |
12: 111,790,249 (GRCm39) |
L84F |
probably damaging |
Het |
|
| Other mutations in Myh4 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01471:Myh4
|
APN |
11 |
67,146,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01600:Myh4
|
APN |
11 |
67,151,015 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
IGL01737:Myh4
|
APN |
11 |
67,134,245 (GRCm39) |
splice site |
probably benign |
|
|
IGL02208:Myh4
|
APN |
11 |
67,142,760 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
IGL02334:Myh4
|
APN |
11 |
67,136,373 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02376:Myh4
|
APN |
11 |
67,136,554 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02429:Myh4
|
APN |
11 |
67,149,808 (GRCm39) |
nonsense |
probably null |
|
|
IGL02450:Myh4
|
APN |
11 |
67,142,635 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02524:Myh4
|
APN |
11 |
67,140,066 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
IGL02612:Myh4
|
APN |
11 |
67,147,305 (GRCm39) |
missense |
probably benign |
|
|
IGL03024:Myh4
|
APN |
11 |
67,139,305 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03065:Myh4
|
APN |
11 |
67,149,982 (GRCm39) |
missense |
probably benign |
0.12 |
|
IGL03084:Myh4
|
APN |
11 |
67,142,777 (GRCm39) |
splice site |
probably null |
|
|
IGL03188:Myh4
|
APN |
11 |
67,137,369 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03204:Myh4
|
APN |
11 |
67,141,122 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
IGL03252:Myh4
|
APN |
11 |
67,143,042 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03345:Myh4
|
APN |
11 |
67,146,304 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Mr_chicken
|
UTSW |
11 |
67,140,711 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
Mrs_muir
|
UTSW |
11 |
67,136,339 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Willies
|
UTSW |
11 |
67,132,335 (GRCm39) |
missense |
probably damaging |
1.00 |
|
F6893:Myh4
|
UTSW |
11 |
67,146,283 (GRCm39) |
missense |
probably null |
0.12 |
|
PIT1430001:Myh4
|
UTSW |
11 |
67,149,658 (GRCm39) |
missense |
probably benign |
0.01 |
|
PIT4458001:Myh4
|
UTSW |
11 |
67,131,821 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R0099:Myh4
|
UTSW |
11 |
67,150,173 (GRCm39) |
missense |
probably benign |
|
|
R0194:Myh4
|
UTSW |
11 |
67,143,162 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0346:Myh4
|
UTSW |
11 |
67,151,152 (GRCm39) |
missense |
probably benign |
|
|
R0427:Myh4
|
UTSW |
11 |
67,149,479 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0483:Myh4
|
UTSW |
11 |
67,143,123 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0571:Myh4
|
UTSW |
11 |
67,141,157 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R0854:Myh4
|
UTSW |
11 |
67,149,973 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0940:Myh4
|
UTSW |
11 |
67,133,689 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0946:Myh4
|
UTSW |
11 |
67,142,577 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R1108:Myh4
|
UTSW |
11 |
67,146,532 (GRCm39) |
missense |
probably null |
0.01 |
|
R1162:Myh4
|
UTSW |
11 |
67,149,439 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1194:Myh4
|
UTSW |
11 |
67,146,560 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1347:Myh4
|
UTSW |
11 |
67,135,567 (GRCm39) |
splice site |
probably benign |
|
|
R1457:Myh4
|
UTSW |
11 |
67,139,287 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1531:Myh4
|
UTSW |
11 |
67,141,366 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1716:Myh4
|
UTSW |
11 |
67,141,135 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1766:Myh4
|
UTSW |
11 |
67,147,121 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R1796:Myh4
|
UTSW |
11 |
67,151,150 (GRCm39) |
missense |
probably benign |
|
|
R1856:Myh4
|
UTSW |
11 |
67,146,508 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1873:Myh4
|
UTSW |
11 |
67,145,569 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2069:Myh4
|
UTSW |
11 |
67,137,192 (GRCm39) |
splice site |
probably benign |
|
|
R2370:Myh4
|
UTSW |
11 |
67,146,454 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2406:Myh4
|
UTSW |
11 |
67,150,000 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2414:Myh4
|
UTSW |
11 |
67,141,594 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2848:Myh4
|
UTSW |
11 |
67,139,459 (GRCm39) |
missense |
probably benign |
0.20 |
|
R3111:Myh4
|
UTSW |
11 |
67,137,276 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R3744:Myh4
|
UTSW |
11 |
67,146,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3845:Myh4
|
UTSW |
11 |
67,149,931 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R3877:Myh4
|
UTSW |
11 |
67,148,009 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4498:Myh4
|
UTSW |
11 |
67,142,578 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4514:Myh4
|
UTSW |
11 |
67,146,395 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4601:Myh4
|
UTSW |
11 |
67,141,136 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4673:Myh4
|
UTSW |
11 |
67,137,227 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4684:Myh4
|
UTSW |
11 |
67,136,637 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4736:Myh4
|
UTSW |
11 |
67,131,746 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4837:Myh4
|
UTSW |
11 |
67,149,818 (GRCm39) |
missense |
probably benign |
0.38 |
|
R4866:Myh4
|
UTSW |
11 |
67,139,453 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4869:Myh4
|
UTSW |
11 |
67,143,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4887:Myh4
|
UTSW |
11 |
67,131,880 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4921:Myh4
|
UTSW |
11 |
67,144,854 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5005:Myh4
|
UTSW |
11 |
67,144,241 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5008:Myh4
|
UTSW |
11 |
67,144,358 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5011:Myh4
|
UTSW |
11 |
67,147,189 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5087:Myh4
|
UTSW |
11 |
67,146,235 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5277:Myh4
|
UTSW |
11 |
67,143,180 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5336:Myh4
|
UTSW |
11 |
67,150,017 (GRCm39) |
splice site |
probably null |
|
|
R5354:Myh4
|
UTSW |
11 |
67,146,551 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R5371:Myh4
|
UTSW |
11 |
67,150,150 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5484:Myh4
|
UTSW |
11 |
67,142,644 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5774:Myh4
|
UTSW |
11 |
67,144,034 (GRCm39) |
nonsense |
probably null |
|
|
R5902:Myh4
|
UTSW |
11 |
67,141,733 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R5941:Myh4
|
UTSW |
11 |
67,150,126 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6045:Myh4
|
UTSW |
11 |
67,135,550 (GRCm39) |
missense |
probably benign |
0.32 |
|
R6156:Myh4
|
UTSW |
11 |
67,141,618 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6301:Myh4
|
UTSW |
11 |
67,146,159 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6318:Myh4
|
UTSW |
11 |
67,134,268 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6352:Myh4
|
UTSW |
11 |
67,143,108 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6385:Myh4
|
UTSW |
11 |
67,146,663 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6493:Myh4
|
UTSW |
11 |
67,149,455 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6666:Myh4
|
UTSW |
11 |
67,142,638 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6826:Myh4
|
UTSW |
11 |
67,137,357 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6852:Myh4
|
UTSW |
11 |
67,143,794 (GRCm39) |
splice site |
probably null |
|
|
R6857:Myh4
|
UTSW |
11 |
67,140,711 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R7029:Myh4
|
UTSW |
11 |
67,137,251 (GRCm39) |
missense |
probably benign |
0.40 |
|
R7076:Myh4
|
UTSW |
11 |
67,143,999 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7145:Myh4
|
UTSW |
11 |
67,151,054 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R7179:Myh4
|
UTSW |
11 |
67,135,550 (GRCm39) |
missense |
probably benign |
0.32 |
|
R7365:Myh4
|
UTSW |
11 |
67,133,674 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7553:Myh4
|
UTSW |
11 |
67,147,221 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7666:Myh4
|
UTSW |
11 |
67,147,107 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7673:Myh4
|
UTSW |
11 |
67,136,339 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7685:Myh4
|
UTSW |
11 |
67,131,756 (GRCm39) |
missense |
probably benign |
0.13 |
|
R8154:Myh4
|
UTSW |
11 |
67,144,200 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8343:Myh4
|
UTSW |
11 |
67,143,390 (GRCm39) |
missense |
possibly damaging |
0.45 |
|
R8446:Myh4
|
UTSW |
11 |
67,144,347 (GRCm39) |
missense |
probably benign |
0.14 |
|
R8534:Myh4
|
UTSW |
11 |
67,134,335 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8710:Myh4
|
UTSW |
11 |
67,143,158 (GRCm39) |
missense |
probably benign |
|
|
R8775:Myh4
|
UTSW |
11 |
67,148,006 (GRCm39) |
missense |
probably benign |
0.25 |
|
R8775-TAIL:Myh4
|
UTSW |
11 |
67,148,006 (GRCm39) |
missense |
probably benign |
0.25 |
|
R8852:Myh4
|
UTSW |
11 |
67,132,335 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8860:Myh4
|
UTSW |
11 |
67,132,335 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8897:Myh4
|
UTSW |
11 |
67,137,362 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8954:Myh4
|
UTSW |
11 |
67,143,806 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8957:Myh4
|
UTSW |
11 |
67,141,780 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R9065:Myh4
|
UTSW |
11 |
67,139,573 (GRCm39) |
missense |
probably benign |
|
|
R9280:Myh4
|
UTSW |
11 |
67,146,135 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9296:Myh4
|
UTSW |
11 |
67,146,130 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9310:Myh4
|
UTSW |
11 |
67,145,570 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9314:Myh4
|
UTSW |
11 |
67,151,141 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9462:Myh4
|
UTSW |
11 |
67,141,811 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9516:Myh4
|
UTSW |
11 |
67,141,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9516:Myh4
|
UTSW |
11 |
67,139,290 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9773:Myh4
|
UTSW |
11 |
67,137,263 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0027:Myh4
|
UTSW |
11 |
67,137,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Myh4
|
UTSW |
11 |
67,147,097 (GRCm39) |
missense |
probably benign |
0.02 |
|
Z1176:Myh4
|
UTSW |
11 |
67,144,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Myh4
|
UTSW |
11 |
67,139,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGCCTGAGAGTCATTTCTTTGG -3'
(R):5'- CATCAATGCTGGGCACTGTG -3'
Sequencing Primer
(F):5'- GCAGATTGGAAAACCTTGCTC -3'
(R):5'- GTGATTTCACCTTGACTGACGTAAGC -3'
|
| Posted On |
2019-10-17 |
Incidental Mutation