Incidental Mutation 'R7514:Arid1b'
| ID |
582355 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Arid1b
|
| Ensembl Gene |
ENSMUSG00000069729 |
| Gene Name |
AT-rich interaction domain 1B |
| Synonyms |
9330189K18Rik, B230217J03Rik |
| MMRRC Submission |
045587-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.783)
|
| Stock # |
R7514 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
17 |
| Chromosomal Location |
5044607-5397931 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 5391989 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Lysine to Glutamic Acid
at position 1787
(K1787E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000090398
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000092723]
[ENSMUST00000115797]
[ENSMUST00000115799]
[ENSMUST00000232180]
|
| AlphaFold |
E9Q4N7 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000092723
AA Change: K1787E
PolyPhen 2
Score 0.284 (Sensitivity: 0.91; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000090398
Gene: ENSMUSG00000069729
AA Change: K1787E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
51 |
N/A |
INTRINSIC |
|
low complexity region
|
69 |
132 |
N/A |
INTRINSIC |
|
low complexity region
|
139 |
150 |
N/A |
INTRINSIC |
|
low complexity region
|
201 |
224 |
N/A |
INTRINSIC |
|
low complexity region
|
232 |
247 |
N/A |
INTRINSIC |
|
low complexity region
|
257 |
276 |
N/A |
INTRINSIC |
|
low complexity region
|
301 |
371 |
N/A |
INTRINSIC |
|
low complexity region
|
379 |
407 |
N/A |
INTRINSIC |
|
low complexity region
|
438 |
476 |
N/A |
INTRINSIC |
|
low complexity region
|
485 |
499 |
N/A |
INTRINSIC |
|
low complexity region
|
538 |
558 |
N/A |
INTRINSIC |
|
low complexity region
|
574 |
591 |
N/A |
INTRINSIC |
|
low complexity region
|
596 |
611 |
N/A |
INTRINSIC |
|
low complexity region
|
615 |
640 |
N/A |
INTRINSIC |
|
low complexity region
|
691 |
707 |
N/A |
INTRINSIC |
|
low complexity region
|
719 |
740 |
N/A |
INTRINSIC |
|
low complexity region
|
743 |
773 |
N/A |
INTRINSIC |
|
low complexity region
|
805 |
816 |
N/A |
INTRINSIC |
|
low complexity region
|
912 |
930 |
N/A |
INTRINSIC |
|
low complexity region
|
936 |
952 |
N/A |
INTRINSIC |
|
low complexity region
|
974 |
985 |
N/A |
INTRINSIC |
|
low complexity region
|
1036 |
1045 |
N/A |
INTRINSIC |
|
ARID
|
1057 |
1147 |
9.9e-33 |
SMART |
|
BRIGHT
|
1061 |
1152 |
7.62e-41 |
SMART |
|
low complexity region
|
1166 |
1177 |
N/A |
INTRINSIC |
|
low complexity region
|
1257 |
1268 |
N/A |
INTRINSIC |
|
low complexity region
|
1336 |
1364 |
N/A |
INTRINSIC |
|
low complexity region
|
1426 |
1456 |
N/A |
INTRINSIC |
|
low complexity region
|
1473 |
1486 |
N/A |
INTRINSIC |
|
low complexity region
|
1579 |
1595 |
N/A |
INTRINSIC |
|
coiled coil region
|
1724 |
1745 |
N/A |
INTRINSIC |
|
low complexity region
|
1835 |
1843 |
N/A |
INTRINSIC |
|
Pfam:DUF3518
|
1933 |
2189 |
1.5e-152 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000115797
AA Change: K1788E
PolyPhen 2
Score 0.284 (Sensitivity: 0.91; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000111463
Gene: ENSMUSG00000069729
AA Change: K1788E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
17 |
80 |
N/A |
INTRINSIC |
|
low complexity region
|
87 |
98 |
N/A |
INTRINSIC |
|
low complexity region
|
149 |
172 |
N/A |
INTRINSIC |
|
low complexity region
|
180 |
195 |
N/A |
INTRINSIC |
|
low complexity region
|
205 |
224 |
N/A |
INTRINSIC |
|
low complexity region
|
249 |
319 |
N/A |
INTRINSIC |
|
low complexity region
|
327 |
355 |
N/A |
INTRINSIC |
|
low complexity region
|
386 |
424 |
N/A |
INTRINSIC |
|
low complexity region
|
433 |
447 |
N/A |
INTRINSIC |
|
low complexity region
|
486 |
506 |
N/A |
INTRINSIC |
|
low complexity region
|
522 |
539 |
N/A |
INTRINSIC |
|
low complexity region
|
544 |
559 |
N/A |
INTRINSIC |
|
low complexity region
|
563 |
588 |
N/A |
INTRINSIC |
|
low complexity region
|
639 |
655 |
N/A |
INTRINSIC |
|
low complexity region
|
667 |
688 |
N/A |
INTRINSIC |
|
low complexity region
|
691 |
721 |
N/A |
INTRINSIC |
|
low complexity region
|
753 |
764 |
N/A |
INTRINSIC |
|
low complexity region
|
860 |
878 |
N/A |
INTRINSIC |
|
low complexity region
|
884 |
900 |
N/A |
INTRINSIC |
|
low complexity region
|
922 |
933 |
N/A |
INTRINSIC |
|
Blast:ARID
|
981 |
1028 |
1e-8 |
BLAST |
|
low complexity region
|
1029 |
1054 |
N/A |
INTRINSIC |
|
ARID
|
1058 |
1148 |
9.9e-33 |
SMART |
|
BRIGHT
|
1062 |
1153 |
7.62e-41 |
SMART |
|
low complexity region
|
1167 |
1178 |
N/A |
INTRINSIC |
|
low complexity region
|
1258 |
1269 |
N/A |
INTRINSIC |
|
low complexity region
|
1337 |
1365 |
N/A |
INTRINSIC |
|
low complexity region
|
1427 |
1457 |
N/A |
INTRINSIC |
|
low complexity region
|
1474 |
1487 |
N/A |
INTRINSIC |
|
low complexity region
|
1580 |
1596 |
N/A |
INTRINSIC |
|
coiled coil region
|
1725 |
1746 |
N/A |
INTRINSIC |
|
low complexity region
|
1836 |
1844 |
N/A |
INTRINSIC |
|
Pfam:DUF3518
|
1935 |
2190 |
6.3e-121 |
PFAM |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000115799
AA Change: K1306E
PolyPhen 2
Score 0.678 (Sensitivity: 0.86; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000111465
Gene: ENSMUSG00000069729
AA Change: K1306E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
34 |
54 |
N/A |
INTRINSIC |
|
low complexity region
|
70 |
87 |
N/A |
INTRINSIC |
|
low complexity region
|
92 |
107 |
N/A |
INTRINSIC |
|
low complexity region
|
111 |
136 |
N/A |
INTRINSIC |
|
low complexity region
|
187 |
203 |
N/A |
INTRINSIC |
|
low complexity region
|
215 |
236 |
N/A |
INTRINSIC |
|
low complexity region
|
271 |
282 |
N/A |
INTRINSIC |
|
low complexity region
|
378 |
396 |
N/A |
INTRINSIC |
|
low complexity region
|
402 |
418 |
N/A |
INTRINSIC |
|
low complexity region
|
440 |
451 |
N/A |
INTRINSIC |
|
Blast:ARID
|
499 |
546 |
1e-8 |
BLAST |
|
low complexity region
|
547 |
572 |
N/A |
INTRINSIC |
|
ARID
|
576 |
666 |
9.9e-33 |
SMART |
|
BRIGHT
|
580 |
671 |
7.62e-41 |
SMART |
|
low complexity region
|
685 |
696 |
N/A |
INTRINSIC |
|
low complexity region
|
776 |
787 |
N/A |
INTRINSIC |
|
low complexity region
|
855 |
883 |
N/A |
INTRINSIC |
|
low complexity region
|
945 |
975 |
N/A |
INTRINSIC |
|
low complexity region
|
992 |
1005 |
N/A |
INTRINSIC |
|
low complexity region
|
1098 |
1114 |
N/A |
INTRINSIC |
|
coiled coil region
|
1243 |
1264 |
N/A |
INTRINSIC |
|
low complexity region
|
1354 |
1362 |
N/A |
INTRINSIC |
|
Pfam:DUF3518
|
1452 |
1708 |
1.1e-152 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000232180
AA Change: K1840E
PolyPhen 2
Score 0.223 (Sensitivity: 0.91; Specificity: 0.88)
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.4%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This locus encodes an AT-rich DNA interacting domain-containing protein. The encoded protein is a component of the SWI/SNF chromatin remodeling complex and may play a role in cell-cycle activation. The protein encoded by this locus is similar to AT-rich interactive domain-containing protein 1A. These two proteins function as alternative, mutually exclusive ARID-subunits of the SWI/SNF complex. The associated complexes play opposing roles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]
|
| Allele List at MGI |
All alleles(61) : Targeted(2) Gene trapped(59)
|
| Other mutations in this stock |
Total: 103 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933427D14Rik |
A |
G |
11: 72,086,628 (GRCm39) |
L261P |
probably damaging |
Het |
| A4gnt |
A |
G |
9: 99,502,598 (GRCm39) |
I253V |
probably benign |
Het |
| AAdacl4fm3 |
A |
T |
4: 144,429,798 (GRCm39) |
V397D |
possibly damaging |
Het |
| Acap2 |
A |
T |
16: 30,973,385 (GRCm39) |
|
probably null |
Het |
| Adora2b |
G |
T |
11: 62,156,146 (GRCm39) |
M198I |
probably damaging |
Het |
| Akap5 |
C |
A |
12: 76,375,303 (GRCm39) |
T245K |
probably benign |
Het |
| Aldh1a2 |
T |
C |
9: 71,192,245 (GRCm39) |
I399T |
probably damaging |
Het |
| Ank2 |
G |
A |
3: 126,819,252 (GRCm39) |
S473L |
probably benign |
Het |
| Anln |
A |
T |
9: 22,272,153 (GRCm39) |
D655E |
probably damaging |
Het |
| Arhgef10 |
T |
C |
8: 15,025,956 (GRCm39) |
V820A |
probably benign |
Het |
| Art4 |
T |
C |
6: 136,831,739 (GRCm39) |
H134R |
probably benign |
Het |
| Borcs6 |
G |
A |
11: 68,951,410 (GRCm39) |
V263M |
probably damaging |
Het |
| C8a |
A |
T |
4: 104,703,247 (GRCm39) |
M314K |
possibly damaging |
Het |
| Cbfa2t3 |
T |
G |
8: 123,361,865 (GRCm39) |
M386L |
probably damaging |
Het |
| Ccdc170 |
T |
A |
10: 4,496,839 (GRCm39) |
V459E |
probably benign |
Het |
| Cdh4 |
T |
A |
2: 179,532,636 (GRCm39) |
N699K |
possibly damaging |
Het |
| Cdk12 |
T |
C |
11: 98,113,484 (GRCm39) |
L756P |
unknown |
Het |
| Chsy1 |
A |
G |
7: 65,821,868 (GRCm39) |
D701G |
probably damaging |
Het |
| Cnot9 |
A |
G |
1: 74,567,921 (GRCm39) |
T270A |
probably benign |
Het |
| Crat |
C |
T |
2: 30,294,577 (GRCm39) |
R497Q |
probably benign |
Het |
| Csnk2a1-ps3 |
A |
G |
1: 156,352,324 (GRCm39) |
D175G |
probably benign |
Het |
| Cyb5r1 |
A |
G |
1: 134,338,268 (GRCm39) |
E228G |
probably damaging |
Het |
| D630003M21Rik |
A |
G |
2: 158,059,273 (GRCm39) |
L209P |
probably damaging |
Het |
| Dennd2c |
T |
A |
3: 103,070,378 (GRCm39) |
D791E |
probably benign |
Het |
| Dnah14 |
T |
C |
1: 181,455,632 (GRCm39) |
I919T |
probably damaging |
Het |
| Dpp8 |
T |
C |
9: 64,986,036 (GRCm39) |
L842S |
probably damaging |
Het |
| Ern1 |
A |
G |
11: 106,300,719 (GRCm39) |
|
probably null |
Het |
| Exo1 |
T |
C |
1: 175,734,232 (GRCm39) |
|
probably null |
Het |
| Fam161b |
T |
G |
12: 84,404,512 (GRCm39) |
E56A |
possibly damaging |
Het |
| Fbrsl1 |
T |
C |
5: 110,580,799 (GRCm39) |
T153A |
probably benign |
Het |
| Fcgr3 |
T |
G |
1: 170,886,912 (GRCm39) |
D4A |
probably benign |
Het |
| Gltp |
C |
T |
5: 114,808,521 (GRCm39) |
A193T |
probably benign |
Het |
| Gm3159 |
A |
T |
14: 4,399,690 (GRCm38) |
S142C |
probably damaging |
Het |
| Gphn |
T |
C |
12: 78,672,939 (GRCm39) |
V485A |
probably damaging |
Het |
| Grik2 |
A |
T |
10: 49,399,904 (GRCm39) |
N275K |
probably damaging |
Het |
| Gstt3 |
G |
T |
10: 75,612,625 (GRCm39) |
Q102K |
probably damaging |
Het |
| Hivep3 |
T |
A |
4: 119,954,052 (GRCm39) |
F789L |
possibly damaging |
Het |
| Ing5 |
A |
G |
1: 93,744,164 (GRCm39) |
N157D |
possibly damaging |
Het |
| Itga3 |
C |
T |
11: 94,956,722 (GRCm39) |
W177* |
probably null |
Het |
| Jag2 |
T |
C |
12: 112,892,672 (GRCm39) |
T83A |
probably benign |
Het |
| Krt90 |
G |
A |
15: 101,461,605 (GRCm39) |
T532I |
unknown |
Het |
| Lcn2 |
A |
G |
2: 32,277,861 (GRCm39) |
|
probably null |
Het |
| Lrig2 |
A |
G |
3: 104,373,076 (GRCm39) |
S602P |
probably damaging |
Het |
| Lsm1 |
A |
C |
8: 26,282,237 (GRCm39) |
R33S |
probably damaging |
Het |
| Mast4 |
A |
T |
13: 102,923,934 (GRCm39) |
Y492* |
probably null |
Het |
| Mcm3 |
A |
T |
1: 20,876,120 (GRCm39) |
L658Q |
probably benign |
Het |
| Myh4 |
G |
A |
11: 67,134,148 (GRCm39) |
|
probably null |
Het |
| Nck2 |
T |
C |
1: 43,608,381 (GRCm39) |
V341A |
probably benign |
Het |
| Nucb1 |
T |
C |
7: 45,151,142 (GRCm39) |
|
probably null |
Het |
| Nup210l |
G |
C |
3: 90,117,766 (GRCm39) |
|
probably null |
Het |
| Or1j1 |
A |
G |
2: 36,702,651 (GRCm39) |
I151T |
probably benign |
Het |
| Or5al5 |
A |
T |
2: 85,961,972 (GRCm39) |
F12I |
probably damaging |
Het |
| Or7g22 |
A |
T |
9: 19,049,161 (GRCm39) |
S291C |
possibly damaging |
Het |
| Or8b48 |
T |
A |
9: 38,493,347 (GRCm39) |
M258K |
probably damaging |
Het |
| Or8b54 |
G |
A |
9: 38,686,974 (GRCm39) |
C141Y |
probably damaging |
Het |
| Pla2g4a |
G |
A |
1: 149,727,113 (GRCm39) |
P556S |
probably damaging |
Het |
| Plat |
T |
C |
8: 23,265,658 (GRCm39) |
C234R |
probably damaging |
Het |
| Ppfia1 |
T |
C |
7: 144,071,450 (GRCm39) |
I321V |
probably benign |
Het |
| Prrc1 |
T |
A |
18: 57,496,325 (GRCm39) |
V92E |
probably benign |
Het |
| Prss3 |
A |
G |
6: 41,350,848 (GRCm39) |
V214A |
probably damaging |
Het |
| Ptprg |
G |
T |
14: 12,179,342 (GRCm38) |
K786N |
possibly damaging |
Het |
| Rabgap1 |
G |
T |
2: 37,427,354 (GRCm39) |
G645V |
probably damaging |
Het |
| Rfx4 |
T |
C |
10: 84,716,090 (GRCm39) |
S470P |
probably damaging |
Het |
| Rin3 |
C |
T |
12: 102,335,909 (GRCm39) |
Q607* |
probably null |
Het |
| Sema3a |
A |
G |
5: 13,573,093 (GRCm39) |
H207R |
probably benign |
Het |
| Serpinb12 |
G |
A |
1: 106,878,534 (GRCm39) |
E181K |
probably damaging |
Het |
| Serpinb6c |
G |
A |
13: 34,081,386 (GRCm39) |
Q88* |
probably null |
Het |
| Shmt1 |
A |
C |
11: 60,692,812 (GRCm39) |
C90W |
probably damaging |
Het |
| Slc16a13 |
C |
T |
11: 70,109,710 (GRCm39) |
V264M |
probably damaging |
Het |
| Slc17a8 |
G |
T |
10: 89,427,969 (GRCm39) |
P286Q |
probably damaging |
Het |
| Slc27a6 |
C |
T |
18: 58,745,293 (GRCm39) |
Q576* |
probably null |
Het |
| Slc30a9 |
T |
C |
5: 67,505,421 (GRCm39) |
S470P |
possibly damaging |
Het |
| Slc44a2 |
G |
T |
9: 21,253,768 (GRCm39) |
K136N |
possibly damaging |
Het |
| Smarca5 |
A |
T |
8: 81,444,163 (GRCm39) |
H534Q |
probably damaging |
Het |
| Son |
T |
G |
16: 91,451,748 (GRCm39) |
L165R |
probably damaging |
Het |
| Sox10 |
G |
A |
15: 79,040,421 (GRCm39) |
P373L |
probably benign |
Het |
| Sp100 |
C |
T |
1: 85,608,860 (GRCm39) |
R330* |
probably null |
Het |
| Srrm4 |
A |
G |
5: 116,584,570 (GRCm39) |
L500P |
probably damaging |
Het |
| Tap1 |
T |
C |
17: 34,415,639 (GRCm39) |
L689P |
probably damaging |
Het |
| Tfg |
A |
G |
16: 56,525,972 (GRCm39) |
|
probably null |
Het |
| Tjp2 |
C |
T |
19: 24,088,886 (GRCm39) |
V677I |
probably benign |
Het |
| Tmprss11g |
T |
G |
5: 86,645,176 (GRCm39) |
D85A |
probably damaging |
Het |
| Tnfsf9 |
T |
C |
17: 57,414,238 (GRCm39) |
S222P |
probably damaging |
Het |
| Trank1 |
A |
G |
9: 111,193,824 (GRCm39) |
N616S |
probably damaging |
Het |
| Tubgcp6 |
C |
A |
15: 89,004,728 (GRCm39) |
W297L |
probably damaging |
Het |
| Twist1 |
T |
C |
12: 34,008,355 (GRCm39) |
S127P |
probably damaging |
Het |
| Ubr4 |
T |
C |
4: 139,179,966 (GRCm39) |
I247T |
unknown |
Het |
| Ubr5 |
G |
A |
15: 37,988,481 (GRCm39) |
T2153M |
|
Het |
| Utrn |
A |
G |
10: 12,573,833 (GRCm39) |
V1079A |
probably benign |
Het |
| Vcan |
T |
C |
13: 89,852,237 (GRCm39) |
T908A |
probably damaging |
Het |
| Vmn2r104 |
A |
G |
17: 20,249,791 (GRCm39) |
F827L |
probably damaging |
Het |
| Vmn2r111 |
T |
A |
17: 22,767,380 (GRCm39) |
T706S |
probably benign |
Het |
| Vmn2r114 |
T |
C |
17: 23,527,035 (GRCm39) |
D499G |
probably null |
Het |
| Vmn2r92 |
T |
C |
17: 18,391,533 (GRCm39) |
S512P |
probably damaging |
Het |
| Vps4b |
A |
T |
1: 106,708,232 (GRCm39) |
|
probably null |
Het |
| Vwa8 |
A |
C |
14: 79,219,674 (GRCm39) |
|
probably null |
Het |
| Wnt10b |
T |
C |
15: 98,672,045 (GRCm39) |
Q224R |
probably benign |
Het |
| Ylpm1 |
C |
T |
12: 85,077,268 (GRCm39) |
P1331L |
possibly damaging |
Het |
| Zfhx4 |
G |
A |
3: 5,307,267 (GRCm39) |
M164I |
possibly damaging |
Het |
| Zfp51 |
A |
G |
17: 21,683,762 (GRCm39) |
T126A |
probably benign |
Het |
| Zfp609 |
A |
G |
9: 65,613,418 (GRCm39) |
V339A |
probably benign |
Het |
| Zfp687 |
C |
T |
3: 94,914,841 (GRCm39) |
R1220H |
probably damaging |
Het |
| Zfyve21 |
C |
T |
12: 111,790,249 (GRCm39) |
L84F |
probably damaging |
Het |
|
| Other mutations in Arid1b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00325:Arid1b
|
APN |
17 |
5,387,385 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
IGL00340:Arid1b
|
APN |
17 |
5,371,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00886:Arid1b
|
APN |
17 |
5,177,254 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01161:Arid1b
|
APN |
17 |
5,392,674 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01391:Arid1b
|
APN |
17 |
5,369,133 (GRCm39) |
splice site |
probably benign |
|
|
IGL01456:Arid1b
|
APN |
17 |
5,341,510 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02152:Arid1b
|
APN |
17 |
5,364,243 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02288:Arid1b
|
APN |
17 |
5,314,315 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
IGL02713:Arid1b
|
APN |
17 |
5,393,286 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02858:Arid1b
|
APN |
17 |
5,392,166 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02885:Arid1b
|
APN |
17 |
5,392,428 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02989:Arid1b
|
APN |
17 |
5,385,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
FR4449:Arid1b
|
UTSW |
17 |
5,045,864 (GRCm39) |
small insertion |
probably benign |
|
|
PIT4142001:Arid1b
|
UTSW |
17 |
5,389,518 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0048:Arid1b
|
UTSW |
17 |
5,364,309 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0124:Arid1b
|
UTSW |
17 |
5,389,605 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0153:Arid1b
|
UTSW |
17 |
5,393,207 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0465:Arid1b
|
UTSW |
17 |
5,046,535 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R0825:Arid1b
|
UTSW |
17 |
5,392,453 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1172:Arid1b
|
UTSW |
17 |
5,389,575 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1468:Arid1b
|
UTSW |
17 |
5,293,197 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1468:Arid1b
|
UTSW |
17 |
5,293,197 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1616:Arid1b
|
UTSW |
17 |
5,389,569 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1754:Arid1b
|
UTSW |
17 |
5,329,476 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R1760:Arid1b
|
UTSW |
17 |
5,392,088 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1812:Arid1b
|
UTSW |
17 |
5,387,304 (GRCm39) |
missense |
probably benign |
0.10 |
|
R1911:Arid1b
|
UTSW |
17 |
5,393,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3874:Arid1b
|
UTSW |
17 |
5,386,790 (GRCm39) |
splice site |
probably null |
|
|
R3913:Arid1b
|
UTSW |
17 |
5,392,532 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R3916:Arid1b
|
UTSW |
17 |
5,392,928 (GRCm39) |
missense |
probably benign |
0.25 |
|
R3922:Arid1b
|
UTSW |
17 |
5,393,316 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4119:Arid1b
|
UTSW |
17 |
5,046,069 (GRCm39) |
unclassified |
probably benign |
|
|
R4290:Arid1b
|
UTSW |
17 |
5,090,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4291:Arid1b
|
UTSW |
17 |
5,090,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4352:Arid1b
|
UTSW |
17 |
5,147,859 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4386:Arid1b
|
UTSW |
17 |
5,045,247 (GRCm39) |
unclassified |
probably benign |
|
|
R4458:Arid1b
|
UTSW |
17 |
5,293,191 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4524:Arid1b
|
UTSW |
17 |
5,147,895 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4622:Arid1b
|
UTSW |
17 |
5,045,325 (GRCm39) |
unclassified |
probably benign |
|
|
R4723:Arid1b
|
UTSW |
17 |
5,387,565 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4782:Arid1b
|
UTSW |
17 |
5,389,496 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4799:Arid1b
|
UTSW |
17 |
5,389,496 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4910:Arid1b
|
UTSW |
17 |
5,392,478 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4946:Arid1b
|
UTSW |
17 |
5,393,118 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5083:Arid1b
|
UTSW |
17 |
5,364,293 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R5204:Arid1b
|
UTSW |
17 |
5,393,316 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5347:Arid1b
|
UTSW |
17 |
5,341,332 (GRCm39) |
nonsense |
probably null |
|
|
R5553:Arid1b
|
UTSW |
17 |
5,364,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5713:Arid1b
|
UTSW |
17 |
5,387,091 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5820:Arid1b
|
UTSW |
17 |
5,046,529 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R5992:Arid1b
|
UTSW |
17 |
5,045,231 (GRCm39) |
unclassified |
probably benign |
|
|
R6038:Arid1b
|
UTSW |
17 |
5,386,957 (GRCm39) |
missense |
probably benign |
0.07 |
|
R6038:Arid1b
|
UTSW |
17 |
5,386,957 (GRCm39) |
missense |
probably benign |
0.07 |
|
R6153:Arid1b
|
UTSW |
17 |
5,293,107 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6222:Arid1b
|
UTSW |
17 |
5,377,922 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6249:Arid1b
|
UTSW |
17 |
5,329,636 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R6279:Arid1b
|
UTSW |
17 |
5,392,274 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6329:Arid1b
|
UTSW |
17 |
5,387,538 (GRCm39) |
nonsense |
probably null |
|
|
R6368:Arid1b
|
UTSW |
17 |
5,382,808 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R6466:Arid1b
|
UTSW |
17 |
5,377,953 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6861:Arid1b
|
UTSW |
17 |
5,377,961 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7008:Arid1b
|
UTSW |
17 |
5,341,254 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7270:Arid1b
|
UTSW |
17 |
5,046,318 (GRCm39) |
missense |
unknown |
|
|
R7519:Arid1b
|
UTSW |
17 |
5,046,128 (GRCm39) |
small insertion |
probably benign |
|
|
R7519:Arid1b
|
UTSW |
17 |
5,046,119 (GRCm39) |
small insertion |
probably benign |
|
|
R7521:Arid1b
|
UTSW |
17 |
5,392,865 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7521:Arid1b
|
UTSW |
17 |
5,046,119 (GRCm39) |
small insertion |
probably benign |
|
|
R7521:Arid1b
|
UTSW |
17 |
5,046,135 (GRCm39) |
small insertion |
probably benign |
|
|
R7616:Arid1b
|
UTSW |
17 |
5,045,661 (GRCm39) |
missense |
unknown |
|
|
R7654:Arid1b
|
UTSW |
17 |
5,341,360 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7711:Arid1b
|
UTSW |
17 |
5,387,095 (GRCm39) |
missense |
probably benign |
0.28 |
|
R7828:Arid1b
|
UTSW |
17 |
5,147,943 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7864:Arid1b
|
UTSW |
17 |
5,392,530 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7998:Arid1b
|
UTSW |
17 |
5,377,959 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8105:Arid1b
|
UTSW |
17 |
5,341,518 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R8260:Arid1b
|
UTSW |
17 |
5,382,788 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8374:Arid1b
|
UTSW |
17 |
5,392,919 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8779:Arid1b
|
UTSW |
17 |
5,391,809 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8801:Arid1b
|
UTSW |
17 |
5,387,103 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8894:Arid1b
|
UTSW |
17 |
5,377,668 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8982:Arid1b
|
UTSW |
17 |
5,293,316 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9034:Arid1b
|
UTSW |
17 |
5,387,180 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9272:Arid1b
|
UTSW |
17 |
5,386,879 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R9300:Arid1b
|
UTSW |
17 |
5,293,274 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9332:Arid1b
|
UTSW |
17 |
5,045,584 (GRCm39) |
missense |
unknown |
|
|
R9481:Arid1b
|
UTSW |
17 |
5,369,007 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9493:Arid1b
|
UTSW |
17 |
5,046,423 (GRCm39) |
missense |
unknown |
|
|
R9512:Arid1b
|
UTSW |
17 |
5,391,864 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9548:Arid1b
|
UTSW |
17 |
5,385,262 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF007:Arid1b
|
UTSW |
17 |
5,045,869 (GRCm39) |
small insertion |
probably benign |
|
|
RF008:Arid1b
|
UTSW |
17 |
5,045,870 (GRCm39) |
small insertion |
probably benign |
|
|
RF008:Arid1b
|
UTSW |
17 |
5,045,869 (GRCm39) |
small insertion |
probably benign |
|
|
RF025:Arid1b
|
UTSW |
17 |
5,045,871 (GRCm39) |
small insertion |
probably benign |
|
|
RF025:Arid1b
|
UTSW |
17 |
5,045,863 (GRCm39) |
small insertion |
probably benign |
|
|
RF028:Arid1b
|
UTSW |
17 |
5,045,873 (GRCm39) |
small insertion |
probably benign |
|
|
RF032:Arid1b
|
UTSW |
17 |
5,045,863 (GRCm39) |
small insertion |
probably benign |
|
|
RF033:Arid1b
|
UTSW |
17 |
5,045,860 (GRCm39) |
small insertion |
probably benign |
|
|
RF041:Arid1b
|
UTSW |
17 |
5,045,870 (GRCm39) |
small insertion |
probably benign |
|
|
RF045:Arid1b
|
UTSW |
17 |
5,045,858 (GRCm39) |
small insertion |
probably benign |
|
|
RF046:Arid1b
|
UTSW |
17 |
5,045,865 (GRCm39) |
small insertion |
probably benign |
|
|
RF058:Arid1b
|
UTSW |
17 |
5,045,858 (GRCm39) |
small insertion |
probably benign |
|
|
X0023:Arid1b
|
UTSW |
17 |
5,392,668 (GRCm39) |
missense |
probably benign |
0.39 |
|
X0027:Arid1b
|
UTSW |
17 |
5,392,647 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Arid1b
|
UTSW |
17 |
5,046,603 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTCCCTGGAAGATGATTCTGGG -3'
(R):5'- CTTACCCGTGGAGCTTAGAG -3'
Sequencing Primer
(F):5'- AGACGATGATGCTGAGTGTC -3'
(R):5'- CTTAGAGGCGGAGGTGGAC -3'
|
| Posted On |
2019-10-17 |
Incidental Mutation