Mutagenetix > Incidental Mutation

Incidental Mutation 'R7524:Map1a'

582819

Institutional Source

Beutler Lab

Gene Symbol

Map1a

Ensembl Gene

ENSMUSG00000027254

Gene Name

microtubule-associated protein 1 A

Synonyms

Mtap1, Mtap-1, 6330416M19Rik, Mtap1a

MMRRC Submission

045596-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.390) question?

Stock #

R7524 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

121289600-121310832 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

G to A at 121289812 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Valine to Methionine at position 60 (V60M)

Ref Sequence

ENSEMBL: ENSMUSP00000092223 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000094639]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000094639
AA Change: V60M

PolyPhen 2 Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)

SMART Domains

Protein: ENSMUSP00000092223
Gene: ENSMUSG00000027254
AA Change: V60M

Domain	Start	End	E-Value	Type
Blast:Lactamase_B	286	538	2e-54	BLAST
SCOP:d1eq1a_	584	699	8e-5	SMART
low complexity region	743	755	N/A	INTRINSIC
low complexity region	820	833	N/A	INTRINSIC
low complexity region	852	867	N/A	INTRINSIC
low complexity region	897	911	N/A	INTRINSIC
low complexity region	1228	1239	N/A	INTRINSIC
low complexity region	1334	1344	N/A	INTRINSIC
low complexity region	1540	1555	N/A	INTRINSIC
coiled coil region	1573	1602	N/A	INTRINSIC
internal_repeat_1	1616	1726	7.66e-6	PROSPERO
coiled coil region	1747	1771	N/A	INTRINSIC
internal_repeat_1	1774	1888	7.66e-6	PROSPERO
low complexity region	2060	2084	N/A	INTRINSIC
low complexity region	2121	2133	N/A	INTRINSIC
low complexity region	2156	2169	N/A	INTRINSIC
low complexity region	2383	2396	N/A	INTRINSIC
low complexity region	2436	2460	N/A	INTRINSIC
low complexity region	2517	2541	N/A	INTRINSIC
low complexity region	2589	2600	N/A	INTRINSIC
low complexity region	2662	2682	N/A	INTRINSIC
low complexity region	2685	2704	N/A	INTRINSIC
low complexity region	2716	2728	N/A	INTRINSIC
low complexity region	2766	2790	N/A	INTRINSIC
low complexity region	2980	2988	N/A	INTRINSIC

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.7%
20x: 99.0%

Validation Efficiency

100% (79/79)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1A heavy chain and LC2 light chain. Expression of this gene is almost exclusively in the brain. Studies of the rat microtubule-associated protein 1A gene suggested a role in early events of spinal cord development. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit Purkinje cell degeneration. Mice homozygous for a spontaneous mutation exhibit mild ataxia and Purkinje cell degeneration. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 78 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adam29	C	T	8: 55,872,360 (GRCm38)	C353Y	probably damaging	Het
Afap1l2	T	A	19: 56,918,111 (GRCm38)	E452V	probably damaging	Het
AI464131	C	A	4: 41,498,779 (GRCm38)	V284L	probably benign	Het
Ak6	A	G	13: 100,663,907 (GRCm38)	D45G	probably benign	Het
Arhgap17	G	A	7: 123,306,420 (GRCm38)	P334L	probably damaging	Het
Asns	G	T	6: 7,677,259 (GRCm38)		probably null	Het
Bend7	A	G	2: 4,799,980 (GRCm38)	T424A	probably benign	Het
Btbd2	C	T	10: 80,646,444 (GRCm38)	E241K	probably damaging	Het
Commd2	A	C	3: 57,650,148 (GRCm38)	L99W	probably damaging	Het
Cpne9	A	T	6: 113,302,064 (GRCm38)	D473V	probably damaging	Het
Cuzd1	A	T	7: 131,311,618 (GRCm38)	F423L	probably damaging	Het
Cyp2d9	T	C	15: 82,455,945 (GRCm38)	F390L	probably damaging	Het
Dcaf5	T	A	12: 80,376,696 (GRCm38)	Q234L	probably benign	Het
Dennd3	T	G	15: 73,524,246 (GRCm38)	Y201*	probably null	Het
Dnah17	T	C	11: 118,121,481 (GRCm38)	D485G	probably benign	Het
Dnah5	A	T	15: 28,297,066 (GRCm38)	T1469S	possibly damaging	Het
Dnah6	T	C	6: 73,118,099 (GRCm38)	D2167G	probably damaging	Het
Dst	T	C	1: 34,291,893 (GRCm38)	V4921A	possibly damaging	Het
Ephb2	A	G	4: 136,659,709 (GRCm38)	Y736H	probably damaging	Het
Eri2	C	G	7: 119,785,749 (GRCm38)	V510L	probably benign	Het
Eya2	G	A	2: 165,769,326 (GRCm38)		probably null	Het
Fam208a	T	A	14: 27,466,203 (GRCm38)	C869S	probably damaging	Het
Fastkd5	G	T	2: 130,616,128 (GRCm38)	Q181K	probably benign	Het
Fcgbp	T	C	7: 28,102,966 (GRCm38)	S1440P	probably damaging	Het
Fkbp9	G	A	6: 56,868,740 (GRCm38)	V354M	probably damaging	Het
Frmpd1	T	A	4: 45,271,181 (GRCm38)	S304T	probably benign	Het
Gtf2a2	T	A	9: 70,015,347 (GRCm38)	Y3*	probably null	Het
Hagh	G	A	17: 24,861,340 (GRCm38)	V226I	probably benign	Het
Hemk1	T	A	9: 107,328,285 (GRCm38)	I293F	probably benign	Het
Kcna3	A	G	3: 107,037,207 (GRCm38)	E262G	probably damaging	Het
Kcnt2	A	T	1: 140,584,055 (GRCm38)	T983S	probably damaging	Het
Klhdc3	A	T	17: 46,678,414 (GRCm38)	H7Q	probably damaging	Het
Knl1	A	T	2: 119,065,979 (GRCm38)	Q94L	probably damaging	Het
Krt12	T	C	11: 99,419,659 (GRCm38)	D224G	probably damaging	Het
Lats1	T	A	10: 7,701,978 (GRCm38)	S289T	possibly damaging	Het
Man2a2	G	C	7: 80,368,865 (GRCm38)	A82G	probably benign	Het
Mms22l	T	A	4: 24,536,138 (GRCm38)	F536I	possibly damaging	Het
Ms4a14	T	C	19: 11,303,836 (GRCm38)	T453A	unknown	Het
Muc3a	A	C	5: 137,210,563 (GRCm38)	I151S	probably benign	Het
Oaf	G	A	9: 43,222,780 (GRCm38)	R215C	probably damaging	Het
Olfr1019	T	A	2: 85,841,357 (GRCm38)	M145L	probably benign	Het
Olfr1217	T	A	2: 89,023,971 (GRCm38)	I11L	probably benign	Het
Olfr1233	A	G	2: 89,339,877 (GRCm38)	C142R	probably benign	Het
Olfr1507	T	C	14: 52,490,293 (GRCm38)	I224V	probably damaging	Het
Olfr5	T	C	7: 6,480,587 (GRCm38)	N190D	probably benign	Het
Olfr8	T	A	10: 78,955,491 (GRCm38)	Y95*	probably null	Het
Pcdhgb4	A	T	18: 37,721,608 (GRCm38)	D352V	probably benign	Het
Pced1a	A	G	2: 130,422,028 (GRCm38)	F235L	probably benign	Het
Pclo	A	G	5: 14,678,303 (GRCm38)	I2392V	unknown	Het
Pld1	A	T	3: 28,024,321 (GRCm38)	D43V	possibly damaging	Het
Ppp1r1b	C	A	11: 98,350,894 (GRCm38)	A51D	possibly damaging	Het
Prr23a1	T	A	9: 98,842,864 (GRCm38)	L93H	probably damaging	Het
Psg20	T	C	7: 18,684,659 (GRCm38)	D61G	probably benign	Het
Rab40b	T	A	11: 121,388,052 (GRCm38)	I31F	probably damaging	Het
Rasd2	T	C	8: 75,222,081 (GRCm38)	F212L	probably benign	Het
Rbl2	A	G	8: 91,115,193 (GRCm38)	I1006V	probably benign	Het
Sema6c	A	G	3: 95,167,060 (GRCm38)	E59G	probably benign	Het
Slc22a2	G	T	17: 12,606,057 (GRCm38)	V269L	possibly damaging	Het
Slc2a1	C	T	4: 119,132,612 (GRCm38)	P149S	probably damaging	Het
Smad4	T	G	18: 73,675,871 (GRCm38)	E108D	probably damaging	Het
Sorbs2	T	A	8: 45,795,656 (GRCm38)	I648K	probably benign	Het
Suclg1	A	T	6: 73,263,841 (GRCm38)	I118F	probably damaging	Het
Tet2	A	G	3: 133,480,229 (GRCm38)	I1149T	probably benign	Het
Tfr2	G	T	5: 137,583,489 (GRCm38)	V613L	probably benign	Het
Tfr2	T	A	5: 137,571,489 (GRCm38)	Y82*	probably null	Het
Tg	A	T	15: 66,696,161 (GRCm38)	M1305L	probably benign	Het
Tmem176a	A	T	6: 48,844,105 (GRCm38)	M170L	probably benign	Het
Trim71	T	C	9: 114,513,162 (GRCm38)	N684S	probably benign	Het
Tspan9	A	G	6: 127,965,251 (GRCm38)	I212T	probably benign	Het
Ttn	A	G	2: 76,942,975 (GRCm38)	V2361A	possibly damaging	Het
Uqcrc1	C	T	9: 108,936,759 (GRCm38)	T14M	possibly damaging	Het
Vmn2r11	T	C	5: 109,053,982 (GRCm38)	I219V	probably benign	Het
Vmn2r76	C	T	7: 86,230,166 (GRCm38)	G309R	probably benign	Het
Vmn2r76	T	C	7: 86,225,369 (GRCm38)	H800R	probably benign	Het
Xpc	A	T	6: 91,499,531 (GRCm38)	C529S	probably benign	Het
Zfp455	T	A	13: 67,207,624 (GRCm38)	S254T	possibly damaging	Het
Zfp746	T	C	6: 48,064,889 (GRCm38)	H301R	possibly damaging	Het
Zyg11a	A	T	4: 108,192,074 (GRCm38)	I490N	probably damaging	Het

Other mutations in Map1a

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00419:Map1a	APN	2	121,299,027 (GRCm38)	missense	probably damaging	0.99
IGL00826:Map1a	APN	2	121,302,276 (GRCm38)	missense	possibly damaging	0.87
IGL01476:Map1a	APN	2	121,305,207 (GRCm38)	missense	probably damaging	1.00
IGL02029:Map1a	APN	2	121,303,298 (GRCm38)	missense	possibly damaging	0.57
IGL02100:Map1a	APN	2	121,302,846 (GRCm38)	missense	probably damaging	0.99
IGL02136:Map1a	APN	2	121,300,212 (GRCm38)	missense	probably damaging	1.00
IGL02146:Map1a	APN	2	121,299,446 (GRCm38)	missense	probably damaging	1.00
IGL02264:Map1a	APN	2	121,307,313 (GRCm38)	missense	probably damaging	1.00
IGL02456:Map1a	APN	2	121,298,653 (GRCm38)	missense	probably damaging	1.00
IGL02485:Map1a	APN	2	121,299,288 (GRCm38)	missense	probably damaging	1.00
IGL02535:Map1a	APN	2	121,302,177 (GRCm38)	nonsense	probably null
IGL02628:Map1a	APN	2	121,300,104 (GRCm38)	missense	probably damaging	1.00
IGL02721:Map1a	APN	2	121,304,037 (GRCm38)	missense	probably benign	0.44
IGL03273:Map1a	APN	2	121,300,238 (GRCm38)	missense	probably damaging	1.00
IGL03281:Map1a	APN	2	121,305,060 (GRCm38)	missense	probably damaging	1.00
IGL02991:Map1a	UTSW	2	121,301,610 (GRCm38)	missense	probably damaging	0.99
R0096:Map1a	UTSW	2	121,301,505 (GRCm38)	missense	probably damaging	1.00
R0096:Map1a	UTSW	2	121,301,505 (GRCm38)	missense	probably damaging	1.00
R0218:Map1a	UTSW	2	121,305,425 (GRCm38)	missense	probably benign	0.00
R0363:Map1a	UTSW	2	121,302,044 (GRCm38)	missense	probably damaging	1.00
R0450:Map1a	UTSW	2	121,305,774 (GRCm38)	missense	probably benign	0.27
R0469:Map1a	UTSW	2	121,305,774 (GRCm38)	missense	probably benign	0.27
R0477:Map1a	UTSW	2	121,302,101 (GRCm38)	missense	probably damaging	1.00
R0504:Map1a	UTSW	2	121,302,941 (GRCm38)	missense	probably benign	0.03
R0510:Map1a	UTSW	2	121,305,774 (GRCm38)	missense	probably benign	0.27
R0521:Map1a	UTSW	2	121,305,753 (GRCm38)	missense	probably damaging	1.00
R0601:Map1a	UTSW	2	121,298,602 (GRCm38)	missense	probably damaging	1.00
R0619:Map1a	UTSW	2	121,305,255 (GRCm38)	missense	probably damaging	0.96
R0633:Map1a	UTSW	2	121,308,014 (GRCm38)	missense	probably damaging	1.00
R0652:Map1a	UTSW	2	121,302,783 (GRCm38)	missense	probably benign	0.04
R0893:Map1a	UTSW	2	121,300,533 (GRCm38)	missense	probably damaging	1.00
R0960:Map1a	UTSW	2	121,301,643 (GRCm38)	missense	probably benign	0.16
R1115:Map1a	UTSW	2	121,307,378 (GRCm38)	splice site	probably null
R1166:Map1a	UTSW	2	121,300,260 (GRCm38)	missense	probably damaging	1.00
R1326:Map1a	UTSW	2	121,306,190 (GRCm38)	nonsense	probably null
R1331:Map1a	UTSW	2	121,306,220 (GRCm38)	nonsense	probably null
R1395:Map1a	UTSW	2	121,303,925 (GRCm38)	missense	probably benign	0.26
R1489:Map1a	UTSW	2	121,300,437 (GRCm38)	missense	possibly damaging	0.91
R1573:Map1a	UTSW	2	121,304,126 (GRCm38)	missense	probably benign	0.37
R1596:Map1a	UTSW	2	121,289,765 (GRCm38)	missense	probably benign	0.00
R1662:Map1a	UTSW	2	121,306,408 (GRCm38)	missense	possibly damaging	0.90
R1675:Map1a	UTSW	2	121,302,655 (GRCm38)	nonsense	probably null
R1919:Map1a	UTSW	2	121,307,012 (GRCm38)	missense	probably damaging	1.00
R2122:Map1a	UTSW	2	121,299,446 (GRCm38)	missense	probably damaging	1.00
R2126:Map1a	UTSW	2	121,298,641 (GRCm38)	missense	probably damaging	0.96
R2143:Map1a	UTSW	2	121,301,945 (GRCm38)	missense	probably damaging	1.00
R2172:Map1a	UTSW	2	121,307,932 (GRCm38)	missense	probably damaging	1.00
R2249:Map1a	UTSW	2	121,300,287 (GRCm38)	missense	probably damaging	1.00
R2254:Map1a	UTSW	2	121,303,791 (GRCm38)	missense	possibly damaging	0.71
R2255:Map1a	UTSW	2	121,303,791 (GRCm38)	missense	possibly damaging	0.71
R3834:Map1a	UTSW	2	121,307,322 (GRCm38)	missense	probably damaging	1.00
R4011:Map1a	UTSW	2	121,300,127 (GRCm38)	missense	probably damaging	1.00
R4346:Map1a	UTSW	2	121,301,325 (GRCm38)	missense	probably benign	0.13
R4842:Map1a	UTSW	2	121,302,086 (GRCm38)	missense	probably damaging	1.00
R4933:Map1a	UTSW	2	121,305,905 (GRCm38)	missense	probably damaging	1.00
R4978:Map1a	UTSW	2	121,301,142 (GRCm38)	missense	probably benign	0.00
R4988:Map1a	UTSW	2	121,303,050 (GRCm38)	missense	probably benign	0.34
R5026:Map1a	UTSW	2	121,307,538 (GRCm38)	missense	possibly damaging	0.83
R5086:Map1a	UTSW	2	121,304,504 (GRCm38)	missense	probably damaging	1.00
R5155:Map1a	UTSW	2	121,302,386 (GRCm38)	missense	probably damaging	1.00
R5232:Map1a	UTSW	2	121,301,985 (GRCm38)	missense	probably damaging	1.00
R5311:Map1a	UTSW	2	121,302,387 (GRCm38)	missense	probably damaging	1.00
R5401:Map1a	UTSW	2	121,299,672 (GRCm38)	missense	probably damaging	1.00
R5465:Map1a	UTSW	2	121,306,025 (GRCm38)	missense	probably damaging	1.00
R5526:Map1a	UTSW	2	121,305,662 (GRCm38)	missense	probably damaging	1.00
R5642:Map1a	UTSW	2	121,306,043 (GRCm38)	missense	probably damaging	1.00
R5726:Map1a	UTSW	2	121,305,065 (GRCm38)	missense	probably damaging	1.00
R5817:Map1a	UTSW	2	121,298,910 (GRCm38)	missense	possibly damaging	0.81
R5855:Map1a	UTSW	2	121,303,674 (GRCm38)	missense	possibly damaging	0.74
R5917:Map1a	UTSW	2	121,305,216 (GRCm38)	missense	probably damaging	1.00
R5974:Map1a	UTSW	2	121,304,376 (GRCm38)	missense	probably benign	0.20
R5987:Map1a	UTSW	2	121,304,295 (GRCm38)	missense	possibly damaging	0.56
R6151:Map1a	UTSW	2	121,289,823 (GRCm38)	missense	probably benign	0.12
R6406:Map1a	UTSW	2	121,300,743 (GRCm38)	missense	probably damaging	1.00
R7014:Map1a	UTSW	2	121,300,239 (GRCm38)	missense	probably damaging	1.00
R7099:Map1a	UTSW	2	121,300,517 (GRCm38)	missense	probably benign	0.04
R7211:Map1a	UTSW	2	121,304,643 (GRCm38)	missense	probably benign	0.02
R7230:Map1a	UTSW	2	121,300,818 (GRCm38)	missense	probably damaging	1.00
R7305:Map1a	UTSW	2	121,299,458 (GRCm38)	missense	probably damaging	1.00
R7382:Map1a	UTSW	2	121,290,785 (GRCm38)	missense	probably damaging	1.00
R7699:Map1a	UTSW	2	121,299,720 (GRCm38)	missense	probably damaging	1.00
R7767:Map1a	UTSW	2	121,302,036 (GRCm38)	missense	probably damaging	1.00
R7883:Map1a	UTSW	2	121,305,372 (GRCm38)	missense	probably damaging	1.00
R7896:Map1a	UTSW	2	121,305,176 (GRCm38)	missense	probably benign	0.00
R7993:Map1a	UTSW	2	121,304,576 (GRCm38)	missense	possibly damaging	0.84
R8270:Map1a	UTSW	2	121,299,020 (GRCm38)	missense	probably damaging	0.99
R8365:Map1a	UTSW	2	121,308,047 (GRCm38)	missense	probably damaging	1.00
R8428:Map1a	UTSW	2	121,304,937 (GRCm38)	missense	probably benign	0.42
R8490:Map1a	UTSW	2	121,304,564 (GRCm38)	missense	possibly damaging	0.93
R8678:Map1a	UTSW	2	121,307,256 (GRCm38)	missense	probably damaging	1.00
R8798:Map1a	UTSW	2	121,302,287 (GRCm38)	missense	probably benign	0.20
R8857:Map1a	UTSW	2	121,307,617 (GRCm38)	missense	probably damaging	1.00
R8878:Map1a	UTSW	2	121,307,644 (GRCm38)	missense	probably damaging	1.00
R8909:Map1a	UTSW	2	121,298,910 (GRCm38)	missense	probably damaging	0.99
R8917:Map1a	UTSW	2	121,301,310 (GRCm38)	missense	possibly damaging	0.93
R8947:Map1a	UTSW	2	121,304,969 (GRCm38)	missense	probably benign	0.27
R9069:Map1a	UTSW	2	121,303,664 (GRCm38)	missense	probably benign	0.15
R9198:Map1a	UTSW	2	121,303,373 (GRCm38)	missense	probably benign	0.00
R9253:Map1a	UTSW	2	121,302,342 (GRCm38)	missense	probably benign	0.00
R9290:Map1a	UTSW	2	121,300,533 (GRCm38)	missense	probably damaging	1.00
R9300:Map1a	UTSW	2	121,302,965 (GRCm38)	missense	probably damaging	1.00
R9589:Map1a	UTSW	2	121,305,917 (GRCm38)	missense	probably damaging	1.00
R9680:Map1a	UTSW	2	121,302,384 (GRCm38)	missense	probably damaging	1.00
R9792:Map1a	UTSW	2	121,290,823 (GRCm38)	critical splice donor site	probably null
R9793:Map1a	UTSW	2	121,290,823 (GRCm38)	critical splice donor site	probably null
R9795:Map1a	UTSW	2	121,290,823 (GRCm38)	critical splice donor site	probably null
RF003:Map1a	UTSW	2	121,306,296 (GRCm38)	small insertion	probably benign
RF007:Map1a	UTSW	2	121,306,308 (GRCm38)	small insertion	probably benign
RF009:Map1a	UTSW	2	121,306,301 (GRCm38)	small insertion	probably benign
RF010:Map1a	UTSW	2	121,306,318 (GRCm38)	small insertion	probably benign
RF014:Map1a	UTSW	2	121,306,295 (GRCm38)	small insertion	probably benign
RF017:Map1a	UTSW	2	121,306,308 (GRCm38)	small insertion	probably benign
RF024:Map1a	UTSW	2	121,306,307 (GRCm38)	small insertion	probably benign
RF025:Map1a	UTSW	2	121,306,294 (GRCm38)	small insertion	probably benign
RF030:Map1a	UTSW	2	121,306,317 (GRCm38)	small insertion	probably benign
RF030:Map1a	UTSW	2	121,306,311 (GRCm38)	small insertion	probably benign
RF033:Map1a	UTSW	2	121,306,299 (GRCm38)	small insertion	probably benign
RF034:Map1a	UTSW	2	121,306,307 (GRCm38)	small insertion	probably benign
RF034:Map1a	UTSW	2	121,306,304 (GRCm38)	small insertion	probably benign
RF035:Map1a	UTSW	2	121,306,301 (GRCm38)	small insertion	probably benign
RF037:Map1a	UTSW	2	121,306,294 (GRCm38)	small insertion	probably benign
RF039:Map1a	UTSW	2	121,306,304 (GRCm38)	small insertion	probably benign
RF042:Map1a	UTSW	2	121,306,287 (GRCm38)	small insertion	probably benign
RF044:Map1a	UTSW	2	121,306,293 (GRCm38)	small insertion	probably benign
RF045:Map1a	UTSW	2	121,306,293 (GRCm38)	small insertion	probably benign
RF051:Map1a	UTSW	2	121,306,296 (GRCm38)	small insertion	probably benign
RF052:Map1a	UTSW	2	121,306,295 (GRCm38)	small insertion	probably benign
RF053:Map1a	UTSW	2	121,306,290 (GRCm38)	small insertion	probably benign
RF060:Map1a	UTSW	2	121,306,318 (GRCm38)	small insertion	probably benign
RF061:Map1a	UTSW	2	121,306,287 (GRCm38)	small insertion	probably benign
Z1176:Map1a	UTSW	2	121,303,238 (GRCm38)	missense	possibly damaging	0.95
Z1177:Map1a	UTSW	2	121,305,279 (GRCm38)	missense	probably damaging	0.99

Predicted Primers

PCR Primer
(F):5'- AGTTTCCATGGCGACCGAAG -3'
(R):5'- GGACAGAGGCACATTCATGG -3'

Sequencing Primer
(F):5'- CGTTGCCATGGAGACAA -3'
(R):5'- GGCACATTCATGGAAGATGC -3'

Posted On

2019-10-17