Mutagenetix > Incidental Mutation

Incidental Mutation 'R0617:Sbf2'

58431

Institutional Source

Beutler Lab

Gene Symbol

Sbf2

Ensembl Gene

ENSMUSG00000038371

Gene Name

SET binding factor 2

Synonyms

mMTMH1, 4833411B01Rik, Mtmr13, B430219L04Rik, SBF2

MMRRC Submission

038806-MU

Accession Numbers

Genbank: NM_177324; MGI: 1921831

Essential gene?

Possibly non essential (E-score: 0.382) question?

Stock #

R0617 (G1)

Quality Score

200

Status

Validated

Chromosome

Chromosomal Location

110308013-110614922 bp(-) (GRCm38)

Type of Mutation

frame shift

DNA Base Change (assembly)

ACC to AC at 110330683 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000126217 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000033058] [ENSMUST00000164759] [ENSMUST00000166020]

AlphaFold

E9PXF8

Predicted Effect

probably null
Transcript: ENSMUST00000033058

SMART Domains

Protein: ENSMUSP00000033058
Gene: ENSMUSG00000038371

Domain	Start	End	E-Value	Type
uDENN	1	87	2.27e-33	SMART
DENN	116	298	5.68e-75	SMART
dDENN	351	420	2e-20	SMART
Pfam:SBF2	530	752	3.3e-106	PFAM
GRAM	869	955	1.3e-12	SMART
low complexity region	1078	1089	N/A	INTRINSIC
Pfam:Myotub-related	1091	1544	8.3e-86	PFAM
PH	1767	1872	3.05e-18	SMART

Predicted Effect

probably null
Transcript: ENSMUST00000164599

SMART Domains

Protein: ENSMUSP00000131927
Gene: ENSMUSG00000038371

Domain	Start	End	E-Value	Type
Pfam:Myotub-related	1	339	1.9e-34	PFAM

Predicted Effect

probably null
Transcript: ENSMUST00000164759

SMART Domains

Protein: ENSMUSP00000132072
Gene: ENSMUSG00000038371

Domain	Start	End	E-Value	Type
uDENN	1	87	2.27e-33	SMART
DENN	116	298	5.68e-75	SMART
dDENN	351	420	2e-20	SMART
Pfam:SBF2	528	752	1.6e-107	PFAM
GRAM	869	955	1.3e-12	SMART
Pfam:Myotub-related	1089	1521	1.6e-98	PFAM
PH	1742	1847	3.05e-18	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000165992

Predicted Effect

probably null
Transcript: ENSMUST00000166020

SMART Domains

Protein: ENSMUSP00000126217
Gene: ENSMUSG00000038371

Domain	Start	End	E-Value	Type
uDENN	1	75	9.26e-1	SMART
DENN	70	252	5.68e-75	SMART
dDENN	305	374	2e-20	SMART
Pfam:SBF2	482	706	1.6e-107	PFAM
GRAM	823	909	1.3e-12	SMART
Pfam:Myotub-related	1043	1500	5.9e-98	PFAM
PH	1721	1826	3.05e-18	SMART

Coding Region Coverage

1x: 99.4%
3x: 98.9%
10x: 97.6%
20x: 95.5%

Validation Efficiency

98% (130/133)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a pseudophosphatase and member of the myotubularin-related protein family. This gene maps within the CMT4B2 candidate region of chromosome 11p15 and mutations in this gene have been associated with Charcot-Marie-Tooth Disease, type 4B2. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for null alleles display progressive misfolding of myelin sheaths and abnormal nerve electrophysiology. [provided by MGI curators]

Allele List at MGI

All alleles(11) : Targeted, other(2) Gene trapped(9)

Other mutations in this stock

Total: 130 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700017D01Rik	C	A	19: 11,112,400 (GRCm38)	L40F	probably damaging	Het
4930555F03Rik	A	T	8: 49,500,492 (GRCm38)		noncoding transcript	Het
A630073D07Rik	T	C	6: 132,626,737 (GRCm38)		probably benign	Het
Abca16	G	A	7: 120,433,611 (GRCm38)		probably benign	Het
Abca5	A	T	11: 110,279,689 (GRCm38)	D1265E	probably damaging	Het
Abcf1	C	T	17: 35,961,187 (GRCm38)	V312I	probably benign	Het
Abhd12	T	A	2: 150,846,365 (GRCm38)		probably null	Het
Adam23	A	G	1: 63,543,147 (GRCm38)	H318R	probably benign	Het
Adcy2	T	A	13: 68,678,606 (GRCm38)	K660*	probably null	Het
Adgrf3	T	C	5: 30,195,080 (GRCm38)	T972A	probably benign	Het
Adipoq	T	A	16: 23,155,410 (GRCm38)	D62E	probably damaging	Het
Akap2	T	C	4: 57,829,434 (GRCm38)		probably benign	Het
Alk	G	T	17: 72,603,583 (GRCm38)	P43T	probably damaging	Het
Arap2	AT	ATT	5: 62,649,907 (GRCm38)		probably benign	Het
Arhgef28	G	T	13: 97,970,355 (GRCm38)	T687K	probably benign	Het
Arrb1	T	C	7: 99,594,677 (GRCm38)	L278P	probably damaging	Het
Atad2b	C	A	12: 4,937,401 (GRCm38)	D76E	probably benign	Het
Atm	A	T	9: 53,458,941 (GRCm38)	Y2290*	probably null	Het
Atrn	T	A	2: 130,995,085 (GRCm38)		probably null	Het
Bpifb1	A	G	2: 154,212,947 (GRCm38)	D253G	possibly damaging	Het
Bpifb9b	C	T	2: 154,319,625 (GRCm38)	T559M	probably benign	Het
Bsn	T	C	9: 108,107,240 (GRCm38)	E3205G	unknown	Het
Cacna1c	T	C	6: 118,602,213 (GRCm38)	Y1599C	probably damaging	Het
Ccdc40	A	G	11: 119,242,804 (GRCm38)	D590G	probably damaging	Het
Ccdc68	A	G	18: 69,946,552 (GRCm38)		probably null	Het
Ccdc97	G	A	7: 25,714,420 (GRCm38)	R279C	probably damaging	Het
Ccm2l	A	G	2: 153,070,900 (GRCm38)	T120A	probably damaging	Het
Cfap54	T	C	10: 92,829,650 (GRCm38)		probably benign	Het
Cfh	A	G	1: 140,100,883 (GRCm38)	S1043P	probably benign	Het
Chil3	T	C	3: 106,155,756 (GRCm38)	K173E	probably benign	Het
Cib2	T	C	9: 54,554,496 (GRCm38)	D26G	possibly damaging	Het
Col24a1	T	C	3: 145,314,120 (GRCm38)	V84A	probably damaging	Het
Csn3	T	C	5: 87,929,871 (GRCm38)	Y79H	probably benign	Het
Ddx47	T	A	6: 135,017,122 (GRCm38)	V149E	probably damaging	Het
Dennd5b	A	T	6: 149,033,262 (GRCm38)		probably benign	Het
Desi1	T	C	15: 81,998,198 (GRCm38)	N109D	probably damaging	Het
Fam13c	T	C	10: 70,536,352 (GRCm38)		probably benign	Het
Fam234a	A	T	17: 26,216,617 (GRCm38)	D264E	probably benign	Het
Fanca	A	G	8: 123,288,070 (GRCm38)	F831S	probably damaging	Het
Fancm	C	T	12: 65,097,317 (GRCm38)	R518*	probably null	Het
Fat2	A	G	11: 55,311,843 (GRCm38)	V135A	possibly damaging	Het
Fbxl17	A	C	17: 63,384,992 (GRCm38)	F42V	probably damaging	Het
Fgd3	A	T	13: 49,264,697 (GRCm38)	V631E	possibly damaging	Het
Fhod3	G	A	18: 25,112,679 (GRCm38)		probably benign	Het
Focad	T	C	4: 88,121,288 (GRCm38)		probably benign	Het
Foxn4	C	A	5: 114,261,068 (GRCm38)		probably benign	Het
Gm1673	T	C	5: 33,983,552 (GRCm38)		probably benign	Het
Gm2381	A	T	7: 42,819,978 (GRCm38)	C241S	probably damaging	Het
Gm6483	T	G	8: 19,693,709 (GRCm38)	F117V	probably damaging	Het
Hectd4	T	C	5: 121,343,232 (GRCm38)		probably benign	Het
Hecw1	T	A	13: 14,280,442 (GRCm38)	Q676L	probably benign	Het
Hipk2	G	A	6: 38,747,485 (GRCm38)	R437C	possibly damaging	Het
Ifnar1	T	C	16: 91,501,682 (GRCm38)	Y396H	probably damaging	Het
Ints5	A	T	19: 8,896,019 (GRCm38)	K447N	probably damaging	Het
Iqsec1	T	C	6: 90,689,970 (GRCm38)	Y495C	probably damaging	Het
Itga5	C	T	15: 103,356,315 (GRCm38)		probably null	Het
Kcnk4	T	A	19: 6,928,160 (GRCm38)		probably benign	Het
Kmo	A	G	1: 175,647,190 (GRCm38)	T174A	possibly damaging	Het
Krt36	T	C	11: 100,102,275 (GRCm38)	D458G	probably damaging	Het
Krtap16-1	G	T	11: 99,986,495 (GRCm38)	P28T	probably damaging	Het
Lama3	T	C	18: 12,419,258 (GRCm38)		probably null	Het
Lrrc9	T	C	12: 72,483,014 (GRCm38)	S920P	probably damaging	Het
Lrrk2	A	T	15: 91,752,278 (GRCm38)	Y1485F	probably benign	Het
Mical1	C	T	10: 41,481,315 (GRCm38)	A372V	probably damaging	Het
Mtr	C	T	13: 12,221,432 (GRCm38)	R636Q	probably benign	Het
Muc4	A	T	16: 32,752,107 (GRCm38)	T662S	possibly damaging	Het
Myo10	G	A	15: 25,738,005 (GRCm38)	V546M	probably damaging	Het
Nbeal1	G	A	1: 60,281,832 (GRCm38)	W2034*	probably null	Het
Nhlrc3	T	C	3: 53,458,623 (GRCm38)	T150A	probably damaging	Het
Nkx2-1	T	C	12: 56,534,855 (GRCm38)	H69R	possibly damaging	Het
Nlrp4g	A	T	9: 124,349,540 (GRCm38)		noncoding transcript	Het
Nod2	A	G	8: 88,653,231 (GRCm38)	N120S	probably benign	Het
Nol8	T	C	13: 49,654,445 (GRCm38)	F46L	possibly damaging	Het
Ntrk1	T	C	3: 87,783,933 (GRCm38)	D308G	possibly damaging	Het
Olfr1036	A	G	2: 86,075,141 (GRCm38)	M134V	probably benign	Het
Olfr1124	A	G	2: 87,434,661 (GRCm38)	D58G	probably damaging	Het
Olfr1196	A	G	2: 88,700,696 (GRCm38)	V211A	probably damaging	Het
Olfr1459	T	C	19: 13,146,363 (GRCm38)	M99V	probably benign	Het
Olfr1477	C	A	19: 13,502,536 (GRCm38)	N64K	probably damaging	Het
Olfr313	T	C	11: 58,817,149 (GRCm38)	V47A	probably damaging	Het
Olfr466	A	T	13: 65,152,878 (GRCm38)	Y218F	possibly damaging	Het
Olfr640	A	T	7: 104,021,989 (GRCm38)	S110T	probably damaging	Het
Oog3	A	T	4: 144,160,214 (GRCm38)	V112D	probably benign	Het
Pcdhb8	C	T	18: 37,357,047 (GRCm38)	R593C	probably benign	Het
Pgm3	A	G	9: 86,556,190 (GRCm38)		probably null	Het
Pirt	T	A	11: 66,926,172 (GRCm38)	V103E	probably damaging	Het
Plxnc1	T	A	10: 94,799,368 (GRCm38)	D1332V	probably damaging	Het
Ppfia4	A	T	1: 134,328,780 (GRCm38)	V122E	probably damaging	Het
Pramef17	A	G	4: 143,993,518 (GRCm38)		probably benign	Het
Prmt2	C	T	10: 76,208,683 (GRCm38)		probably benign	Het
Prrc2a	G	T	17: 35,153,560 (GRCm38)	P1702T	probably damaging	Het
Prss39	A	T	1: 34,500,198 (GRCm38)	H173L	probably damaging	Het
Rabl6	A	G	2: 25,586,866 (GRCm38)		probably null	Het
Rb1cc1	T	A	1: 6,248,790 (GRCm38)	I794K	possibly damaging	Het
Reln	T	C	5: 21,920,537 (GRCm38)	D2716G	probably damaging	Het
Sema6d	T	A	2: 124,660,745 (GRCm38)	F583L	possibly damaging	Het
Setx	T	A	2: 29,146,807 (GRCm38)	H1101Q	possibly damaging	Het
Sis	A	G	3: 72,965,605 (GRCm38)	C67R	probably damaging	Het
Skint1	T	A	4: 112,029,399 (GRCm38)		probably benign	Het
Smg6	C	A	11: 75,162,931 (GRCm38)	T1413K	probably benign	Het
Spata31d1a	A	T	13: 59,702,259 (GRCm38)	I685N	possibly damaging	Het
Spef2	T	A	15: 9,592,758 (GRCm38)	N1499I	probably damaging	Het
Stk11ip	T	A	1: 75,532,288 (GRCm38)		probably null	Het
Stxbp1	A	C	2: 32,802,783 (GRCm38)	I407S	probably damaging	Het
Svil	T	C	18: 5,117,002 (GRCm38)	S2059P	probably damaging	Het
Syne1	C	T	10: 5,350,933 (GRCm38)	V932M	probably damaging	Het
Tacc1	A	C	8: 25,178,004 (GRCm38)		probably benign	Het
Tbc1d13	C	A	2: 30,135,564 (GRCm38)		probably benign	Het
Tbc1d15	A	C	10: 115,239,299 (GRCm38)	D59E	probably damaging	Het
Tcaf2	A	G	6: 42,642,511 (GRCm38)	F194S	probably damaging	Het
Terf2ip	T	A	8: 112,011,495 (GRCm38)	M5K	probably benign	Het
Tgfbr2	A	T	9: 116,158,320 (GRCm38)	D40E	probably benign	Het
Tm4sf5	T	A	11: 70,510,669 (GRCm38)	S165T	probably damaging	Het
Tmprss3	A	T	17: 31,193,912 (GRCm38)	C129S	probably damaging	Het
Tmx2	T	C	2: 84,672,396 (GRCm38)	D256G	probably benign	Het
Tnr	A	G	1: 159,868,103 (GRCm38)	D532G	probably damaging	Het
Tnrc18	T	A	5: 142,776,739 (GRCm38)	H465L	unknown	Het
Togaram2	A	T	17: 71,700,509 (GRCm38)	Q350L	possibly damaging	Het
Topaz1	G	A	9: 122,749,906 (GRCm38)	C627Y	possibly damaging	Het
Tpx2	A	T	2: 152,873,138 (GRCm38)	Q93L	probably benign	Het
Trim54	T	C	5: 31,136,182 (GRCm38)		probably null	Het
Troap	T	A	15: 99,082,660 (GRCm38)	C574S	probably damaging	Het
Ubr4	T	C	4: 139,479,062 (GRCm38)		probably null	Het
Vmn2r51	A	G	7: 10,100,469 (GRCm38)	V214A	possibly damaging	Het
Vmn2r66	A	T	7: 84,995,276 (GRCm38)	M642K	probably benign	Het
Vwa5a	T	A	9: 38,723,895 (GRCm38)	I232N	probably damaging	Het
Zcchc6	A	T	13: 59,816,855 (GRCm38)		probably null	Het
Zfp820	A	T	17: 21,819,704 (GRCm38)	S214R	probably damaging	Het
Zfp955b	A	T	17: 33,305,463 (GRCm38)	S43R	probably damaging	Het
Zgrf1	C	T	3: 127,588,038 (GRCm38)	T1162M	probably benign	Het

Other mutations in Sbf2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00421:Sbf2	APN	7	110,375,832 (GRCm38)	splice site	probably benign
IGL01089:Sbf2	APN	7	110,348,962 (GRCm38)	missense	probably damaging	1.00
IGL01144:Sbf2	APN	7	110,329,903 (GRCm38)	missense	probably damaging	1.00
IGL01652:Sbf2	APN	7	110,447,120 (GRCm38)	missense	probably damaging	1.00
IGL01950:Sbf2	APN	7	110,365,825 (GRCm38)	missense	probably benign	0.00
IGL02027:Sbf2	APN	7	110,461,141 (GRCm38)	missense	probably damaging	1.00
IGL02244:Sbf2	APN	7	110,560,295 (GRCm38)	missense	probably damaging	1.00
IGL02376:Sbf2	APN	7	110,462,956 (GRCm38)	missense	probably damaging	0.99
IGL03405:Sbf2	APN	7	110,462,932 (GRCm38)	missense	probably damaging	0.98
N/A - 535:Sbf2	UTSW	7	110,312,752 (GRCm38)	missense	probably benign
R0084:Sbf2	UTSW	7	110,442,366 (GRCm38)	missense	possibly damaging	0.95
R0092:Sbf2	UTSW	7	110,320,806 (GRCm38)	splice site	probably benign
R0121:Sbf2	UTSW	7	110,489,219 (GRCm38)	critical splice donor site	probably null
R0464:Sbf2	UTSW	7	110,464,576 (GRCm38)	splice site	probably benign
R0505:Sbf2	UTSW	7	110,399,343 (GRCm38)	missense	probably damaging	1.00
R0531:Sbf2	UTSW	7	110,367,323 (GRCm38)	splice site	probably benign
R0554:Sbf2	UTSW	7	110,428,287 (GRCm38)	missense	probably damaging	1.00
R0619:Sbf2	UTSW	7	110,310,262 (GRCm38)	missense	possibly damaging	0.87
R0799:Sbf2	UTSW	7	110,341,355 (GRCm38)	missense	possibly damaging	0.58
R0898:Sbf2	UTSW	7	110,371,652 (GRCm38)	missense	possibly damaging	0.59
R1077:Sbf2	UTSW	7	110,367,172 (GRCm38)	splice site	probably benign
R1167:Sbf2	UTSW	7	110,364,549 (GRCm38)	missense	probably damaging	1.00
R1169:Sbf2	UTSW	7	110,310,184 (GRCm38)	missense	probably benign	0.04
R1424:Sbf2	UTSW	7	110,315,026 (GRCm38)	missense	probably damaging	1.00
R1536:Sbf2	UTSW	7	110,378,043 (GRCm38)	missense	probably damaging	1.00
R1558:Sbf2	UTSW	7	110,428,346 (GRCm38)	missense	probably damaging	1.00
R1601:Sbf2	UTSW	7	110,340,076 (GRCm38)	critical splice acceptor site	probably null
R1762:Sbf2	UTSW	7	110,312,758 (GRCm38)	missense	probably benign
R1771:Sbf2	UTSW	7	110,461,146 (GRCm38)	nonsense	probably null
R1989:Sbf2	UTSW	7	110,348,923 (GRCm38)	missense	possibly damaging	0.94
R2109:Sbf2	UTSW	7	110,461,212 (GRCm38)	missense	probably damaging	1.00
R2126:Sbf2	UTSW	7	110,560,295 (GRCm38)	missense	probably damaging	1.00
R2444:Sbf2	UTSW	7	110,330,698 (GRCm38)	missense	probably benign	0.31
R3765:Sbf2	UTSW	7	110,375,581 (GRCm38)	missense	probably damaging	1.00
R3808:Sbf2	UTSW	7	110,489,280 (GRCm38)	makesense	probably null
R3895:Sbf2	UTSW	7	110,447,091 (GRCm38)	missense	probably damaging	0.99
R3978:Sbf2	UTSW	7	110,329,885 (GRCm38)	missense	probably benign	0.00
R4056:Sbf2	UTSW	7	110,441,466 (GRCm38)	missense	probably damaging	0.99
R4057:Sbf2	UTSW	7	110,441,466 (GRCm38)	missense	probably damaging	0.99
R4111:Sbf2	UTSW	7	110,428,242 (GRCm38)	missense	probably damaging	1.00
R4569:Sbf2	UTSW	7	110,348,853 (GRCm38)	critical splice donor site	probably null
R4670:Sbf2	UTSW	7	110,335,399 (GRCm38)	missense	probably damaging	1.00
R4763:Sbf2	UTSW	7	110,420,917 (GRCm38)	missense	probably damaging	1.00
R4792:Sbf2	UTSW	7	110,351,610 (GRCm38)	missense	probably damaging	0.98
R4811:Sbf2	UTSW	7	110,372,535 (GRCm38)	missense	probably damaging	1.00
R4822:Sbf2	UTSW	7	110,377,939 (GRCm38)	intron	probably benign
R5110:Sbf2	UTSW	7	110,364,657 (GRCm38)	missense	probably benign	0.10
R5143:Sbf2	UTSW	7	110,422,540 (GRCm38)	nonsense	probably null
R5443:Sbf2	UTSW	7	110,377,928 (GRCm38)	intron	probably benign
R5457:Sbf2	UTSW	7	110,312,830 (GRCm38)	missense	probably benign
R5641:Sbf2	UTSW	7	110,438,901 (GRCm38)	missense	probably damaging	1.00
R5915:Sbf2	UTSW	7	110,378,096 (GRCm38)	nonsense	probably null
R5948:Sbf2	UTSW	7	110,489,285 (GRCm38)	missense	probably damaging	1.00
R5977:Sbf2	UTSW	7	110,377,986 (GRCm38)	missense	probably benign	0.00
R6052:Sbf2	UTSW	7	110,441,534 (GRCm38)	missense	probably damaging	1.00
R6142:Sbf2	UTSW	7	110,348,975 (GRCm38)	missense	probably damaging	1.00
R6327:Sbf2	UTSW	7	110,441,552 (GRCm38)	missense	probably damaging	1.00
R6356:Sbf2	UTSW	7	110,372,623 (GRCm38)	missense	probably damaging	1.00
R6450:Sbf2	UTSW	7	110,462,863 (GRCm38)	missense	probably damaging	1.00
R6587:Sbf2	UTSW	7	110,440,975 (GRCm38)	missense	probably damaging	1.00
R6696:Sbf2	UTSW	7	110,560,298 (GRCm38)	missense	probably benign	0.04
R6986:Sbf2	UTSW	7	110,330,615 (GRCm38)	missense	probably damaging	0.99
R7147:Sbf2	UTSW	7	110,447,061 (GRCm38)	missense	probably benign	0.01
R7358:Sbf2	UTSW	7	110,399,348 (GRCm38)	missense	possibly damaging	0.95
R7414:Sbf2	UTSW	7	110,314,064 (GRCm38)	missense	possibly damaging	0.89
R7418:Sbf2	UTSW	7	110,365,821 (GRCm38)	missense	probably damaging	1.00
R7423:Sbf2	UTSW	7	110,438,848 (GRCm38)	missense	possibly damaging	0.48
R7425:Sbf2	UTSW	7	110,375,777 (GRCm38)	nonsense	probably null
R7431:Sbf2	UTSW	7	110,351,750 (GRCm38)	missense	probably damaging	1.00
R7497:Sbf2	UTSW	7	110,614,716 (GRCm38)	nonsense	probably null
R7556:Sbf2	UTSW	7	110,314,053 (GRCm38)	missense	probably benign	0.20
R7604:Sbf2	UTSW	7	110,378,067 (GRCm38)	missense	possibly damaging	0.95
R7707:Sbf2	UTSW	7	110,330,713 (GRCm38)	critical splice acceptor site	probably null
R7746:Sbf2	UTSW	7	110,441,426 (GRCm38)	missense	probably benign	0.01
R7812:Sbf2	UTSW	7	110,449,963 (GRCm38)	missense	possibly damaging	0.84
R7849:Sbf2	UTSW	7	110,372,510 (GRCm38)	missense	probably damaging	1.00
R8026:Sbf2	UTSW	7	110,335,387 (GRCm38)	missense	probably damaging	1.00
R8048:Sbf2	UTSW	7	110,315,082 (GRCm38)	missense	probably benign	0.21
R8305:Sbf2	UTSW	7	110,371,618 (GRCm38)	missense	possibly damaging	0.79
R8337:Sbf2	UTSW	7	110,441,462 (GRCm38)	missense	probably benign
R8773:Sbf2	UTSW	7	110,348,995 (GRCm38)	missense	probably benign
R8786:Sbf2	UTSW	7	110,464,586 (GRCm38)	critical splice donor site	probably null
R8812:Sbf2	UTSW	7	110,329,862 (GRCm38)	missense	probably damaging	1.00
R8876:Sbf2	UTSW	7	110,449,939 (GRCm38)	missense	probably damaging	0.99
R8932:Sbf2	UTSW	7	110,440,948 (GRCm38)	critical splice donor site	probably null
R8954:Sbf2	UTSW	7	110,438,911 (GRCm38)	nonsense	probably null
R8991:Sbf2	UTSW	7	110,312,689 (GRCm38)	missense	probably benign	0.20
R9119:Sbf2	UTSW	7	110,312,085 (GRCm38)	missense	possibly damaging	0.93
R9310:Sbf2	UTSW	7	110,315,085 (GRCm38)	missense	possibly damaging	0.58
R9344:Sbf2	UTSW	7	110,341,328 (GRCm38)	missense	probably benign	0.10
R9346:Sbf2	UTSW	7	110,320,739 (GRCm38)	missense	probably benign	0.05
R9404:Sbf2	UTSW	7	110,441,495 (GRCm38)	missense	possibly damaging	0.81
R9406:Sbf2	UTSW	7	110,441,495 (GRCm38)	missense	possibly damaging	0.81
R9408:Sbf2	UTSW	7	110,441,495 (GRCm38)	missense	possibly damaging	0.81
R9472:Sbf2	UTSW	7	110,371,591 (GRCm38)	missense	possibly damaging	0.88
R9554:Sbf2	UTSW	7	110,441,464 (GRCm38)	missense	probably damaging	1.00
R9562:Sbf2	UTSW	7	110,441,495 (GRCm38)	missense	possibly damaging	0.81
R9624:Sbf2	UTSW	7	110,364,650 (GRCm38)	missense	probably damaging	1.00
R9652:Sbf2	UTSW	7	110,441,495 (GRCm38)	missense	possibly damaging	0.81
R9653:Sbf2	UTSW	7	110,441,495 (GRCm38)	missense	possibly damaging	0.81
R9709:Sbf2	UTSW	7	110,428,307 (GRCm38)	missense	probably damaging	0.99
RF005:Sbf2	UTSW	7	110,317,008 (GRCm38)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- CACCTGAACGTGGGAAAGGTCTAAC -3'
(R):5'- GAAACTACCGTTTTGCCTTGGGAATTG -3'

Sequencing Primer
(F):5'- TGTTCGACAGCTTGCCAG -3'
(R):5'- GTGTTTGCTCTAATTGAAGCCTTC -3'

Posted On

2013-07-11