Mutagenetix > Incidental Mutation

Incidental Mutation 'R7553:Dmbt1'

584556

Institutional Source

Beutler Lab

Gene Symbol

Dmbt1

Ensembl Gene

ENSMUSG00000047517

Gene Name

deleted in malignant brain tumors 1

Synonyms

CRP-[a], Crpd, gp300, vomeroglandin, CRP-[b], ebnerin, MUCLIN, hensin

MMRRC Submission

045622-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.194) question?

Stock #

R7553 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

131032053-131121630 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 131104867 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Asparagine to Serine at position 1372 (N1372S)

Ref Sequence

ENSEMBL: ENSMUSP00000146685 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000084509] [ENSMUST00000124096] [ENSMUST00000208311] [ENSMUST00000213064]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000084509
AA Change: N1361S

PolyPhen 2 Score 0.015 (Sensitivity: 0.96; Specificity: 0.79)

SMART Domains

Protein: ENSMUSP00000081556
Gene: ENSMUSG00000047517
AA Change: N1361S

Domain	Start	End	E-Value	Type
SR	37	137	5.54e-59	SMART
SR	186	286	3.6e-58	SMART
SR	324	424	1.21e-59	SMART
SR	463	563	2.97e-59	SMART
SR	602	702	3.36e-58	SMART
SR	741	841	5.17e-59	SMART
low complexity region	848	879	N/A	INTRINSIC
CUB	884	993	4.22e-41	SMART
CUB	1000	1109	7.35e-41	SMART
CUB	1126	1235	3.73e-42	SMART
CUB	1242	1351	2.02e-38	SMART
SR	1371	1471	3.92e-59	SMART
low complexity region	1476	1488	N/A	INTRINSIC
CUB	1494	1603	6.7e-44	SMART
ZP	1612	1860	8.11e-74	SMART
transmembrane domain	1906	1928	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000124096

SMART Domains

Protein: ENSMUSP00000130971
Gene: ENSMUSG00000030849

Domain	Start	End	E-Value	Type
Pfam:Pkinase	1	118	4.8e-19	PFAM
Pfam:Pkinase_Tyr	1	118	1.7e-50	PFAM
low complexity region	146	160	N/A	INTRINSIC

Predicted Effect

unknown
Transcript: ENSMUST00000208311
AA Change: N1372S

Predicted Effect

probably benign
Transcript: ENSMUST00000213064
AA Change: N1198S

PolyPhen 2 Score 0.026 (Sensitivity: 0.95; Specificity: 0.81)

Meta Mutation Damage Score

0.0869

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.7%
20x: 99.1%

Validation Efficiency

98% (62/63)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. This gene was originally isolated based on its deletion in a medulloblastoma cell line. This gene is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The encoded protein precursor is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor suppressor gene, but rather play a role in the interaction of tumor cells and the immune system. [provided by RefSeq, Mar 2016]
PHENOTYPE: Mice homozygous for one null allele display embryonic lethality and an abnormal inner cell mass. Mice homozygous for a different null allele are viable and fertile with an increased susceptibility to induced colitis. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 66 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcc6	A	G	7: 45,999,121 (GRCm38)	L649P	probably damaging	Het
Acad10	T	C	5: 121,639,255 (GRCm38)	Y371C	probably damaging	Het
Avp	A	G	2: 130,581,178 (GRCm38)	V71A	probably damaging	Het
Bhmt	C	T	13: 93,620,081 (GRCm38)		probably null	Het
Capn15	T	C	17: 25,960,764 (GRCm38)	E874G	probably damaging	Het
Capn5	A	G	7: 98,124,024 (GRCm38)	F591S	probably damaging	Het
Ccne2	A	T	4: 11,201,348 (GRCm38)	Q292L	probably benign	Het
Cd96	T	G	16: 46,052,021 (GRCm38)	T406P	probably damaging	Het
Csnk1e	G	A	15: 79,426,366 (GRCm38)	A153V	probably damaging	Het
Dlk1	G	A	12: 109,454,963 (GRCm38)	V15I	unknown	Het
Dntt	A	T	19: 41,029,487 (GRCm38)	R17W	probably damaging	Het
Erich3	G	T	3: 154,733,500 (GRCm38)	A260S	probably benign	Het
Foxp2	C	T	6: 15,437,882 (GRCm38)	S669L	unknown	Het
Gm40460	ACCCCCACAGGAGCCACAGCCTCCCTTGCAGCCCCCACAGGAGCCACAGCCTCCCTTGCAGCCCCCACAGGAGCCACAGCCTCCCTTGCAGCCCCCACAGGAGCCACAGCCTCCCTTGCAGCCCCCACAGGAACTACAGCCTCCCTTGCAGCCCCCACAGGAACTACAGCCTCCCTTGCAGCCCCCACAGGAACTACAGCCTCCCTTGCAGCCCCCACAG	ACCCCCACAGGAGCCACAGCCTCCCTTGCAGCCCCCACAGGAGCCACAGCCTCCCTTGCAGCCCCCACAGGAGCCACAGCCTCCCTTGCAGCCCCCACAGGAACTACAGCCTCCCTTGCAGCCCCCACAGGAACTACAGCCTCCCTTGCAGCCCCCACAGGAACTACAGCCTCCCTTGCAGCCCCCACAG	7: 142,240,713 (GRCm38)		probably benign	Het
Gm9268	T	G	7: 43,048,023 (GRCm38)	C835G	probably damaging	Het
Grid2	A	G	6: 64,076,941 (GRCm38)	K375E	possibly damaging	Het
Grin2b	C	T	6: 135,772,396 (GRCm38)	G603S	possibly damaging	Het
Hexb	C	T	13: 97,198,173 (GRCm38)	R30Q	probably benign	Het
Homer3	A	T	8: 70,290,124 (GRCm38)	T162S	probably benign	Het
L3mbtl1	A	G	2: 162,948,231 (GRCm38)	E15G	probably benign	Het
Manea	A	T	4: 26,327,986 (GRCm38)	F352I	probably damaging	Het
Mcf2l	T	A	8: 12,997,268 (GRCm38)	M210K	probably benign	Het
Morc3	T	C	16: 93,870,936 (GRCm38)	L734P	probably damaging	Het
Mybpc2	A	G	7: 44,506,147 (GRCm38)	V894A	possibly damaging	Het
Myh4	T	A	11: 67,256,395 (GRCm38)	M1622K	probably damaging	Het
Myrf	A	G	19: 10,228,876 (GRCm38)	F59L	probably benign	Het
Ndst3	G	T	3: 123,557,060 (GRCm38)		probably null	Het
Nln	TGGTCCAGGTAAAACTGCCCCAGCCAATCAGGTACCTTGGATAGAGGTCCAGGTAAAACTGCCCCAGCCAATCAGGTACCTTGGATAGAGGTCCAGGTAGAACTGCCCCAGC	TGGTCCAGGTAAAACTGCCCCAGCCAATCAGGTACCTTGGATAGAGGTCCAGGTAGAACTGCCCCAGC	13: 104,050,416 (GRCm38)		probably null	Het
Nos3	A	T	5: 24,381,717 (GRCm38)	D986V	possibly damaging	Het
Nrp1	G	A	8: 128,431,987 (GRCm38)	A252T	probably damaging	Het
Nup205	G	T	6: 35,201,999 (GRCm38)	R668L	probably damaging	Het
Olfr313	T	A	11: 58,817,060 (GRCm38)	D17E	probably benign	Het
Olfr477	G	A	7: 107,990,475 (GRCm38)	V37I	probably benign	Het
Olfr612	T	C	7: 103,539,156 (GRCm38)	Y26C	probably damaging	Het
Pcdhga1	T	A	18: 37,749,682 (GRCm38)		probably null	Het
Pck1	A	G	2: 173,157,067 (GRCm38)	I373V	probably benign	Het
Pde8b	T	C	13: 95,086,750 (GRCm38)	N227S	probably benign	Het
Pianp	T	G	6: 124,999,251 (GRCm38)	S8A	unknown	Het
Pkd1l3	GACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCA	GACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCA	8: 109,624,195 (GRCm38)		probably benign	Het
Pla2r1	A	T	2: 60,522,899 (GRCm38)	N239K	possibly damaging	Het
Pls1	T	A	9: 95,787,087 (GRCm38)	N27I	probably damaging	Het
Prep	T	C	10: 45,158,524 (GRCm38)	*711Q	probably null	Het
Prkag3	A	G	1: 74,744,735 (GRCm38)	F330L	probably damaging	Het
Prss56	A	G	1: 87,183,539 (GRCm38)	D16G	probably benign	Het
Rad17	A	T	13: 100,633,286 (GRCm38)	F255Y	probably damaging	Het
Rap1gap2	T	C	11: 74,435,722 (GRCm38)	E173G	probably damaging	Het
Retreg3	C	T	11: 101,106,390 (GRCm38)	R88H	possibly damaging	Het
Rhag	G	A	17: 40,828,395 (GRCm38)	G74R	probably damaging	Het
Rybp	A	G	6: 100,232,259 (GRCm38)	S201P	possibly damaging	Het
S100a10	G	A	3: 93,564,295 (GRCm38)	C62Y	probably benign	Het
Scgb2b3	T	A	7: 31,360,248 (GRCm38)	S34C	possibly damaging	Het
Serpind1	A	G	16: 17,336,675 (GRCm38)	D122G	probably benign	Het
Setdb1	A	G	3: 95,346,765 (GRCm38)	L242P	probably damaging	Het
Slc14a2	T	A	18: 78,155,588 (GRCm38)	I776F	probably damaging	Het
Slc9a1	A	G	4: 133,412,269 (GRCm38)	E266G	probably damaging	Het
Stard9	A	T	2: 120,693,808 (GRCm38)		probably null	Het
Stpg2	A	G	3: 139,218,337 (GRCm38)	Y167C	probably damaging	Het
Tex264	T	C	9: 106,659,136 (GRCm38)	E274G	probably damaging	Het
Tigd2	G	A	6: 59,211,579 (GRCm38)	S477N	probably benign	Het
Urb1	A	G	16: 90,792,864 (GRCm38)	L343P	probably damaging	Het
Vars2	A	T	17: 35,664,788 (GRCm38)	C246S	possibly damaging	Het
Vil1	G	A	1: 74,426,732 (GRCm38)		probably null	Het
Vmn2r61	C	G	7: 42,266,781 (GRCm38)	L273V	not run	Het
Zfp37	C	A	4: 62,191,999 (GRCm38)	G317V	probably damaging	Het
Zfp760	A	G	17: 21,722,891 (GRCm38)	K349R	possibly damaging	Het
Zyx	A	T	6: 42,350,474 (GRCm38)	E69V	probably null	Het

Other mutations in Dmbt1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00091:Dmbt1	APN	7	131,079,540 (GRCm38)	intron	probably benign
IGL00161:Dmbt1	APN	7	131,109,628 (GRCm38)	missense	probably damaging	1.00
IGL00331:Dmbt1	APN	7	131,099,290 (GRCm38)	missense	possibly damaging	0.46
IGL00769:Dmbt1	APN	7	131,082,500 (GRCm38)	missense	probably damaging	0.99
IGL00792:Dmbt1	APN	7	131,097,607 (GRCm38)	missense	possibly damaging	0.66
IGL00823:Dmbt1	APN	7	131,058,158 (GRCm38)	missense	probably benign	0.26
IGL01072:Dmbt1	APN	7	131,085,368 (GRCm38)	splice site	probably benign
IGL01317:Dmbt1	APN	7	131,041,191 (GRCm38)	missense	probably damaging	1.00
IGL01335:Dmbt1	APN	7	131,088,767 (GRCm38)	missense	possibly damaging	0.95
IGL01372:Dmbt1	APN	7	131,103,679 (GRCm38)	missense	possibly damaging	0.90
IGL01511:Dmbt1	APN	7	131,116,728 (GRCm38)	missense	possibly damaging	0.49
IGL01627:Dmbt1	APN	7	131,081,185 (GRCm38)	missense	probably benign	0.14
IGL01890:Dmbt1	APN	7	131,074,419 (GRCm38)	intron	probably benign
IGL02160:Dmbt1	APN	7	131,082,688 (GRCm38)	missense	probably damaging	1.00
IGL02186:Dmbt1	APN	7	131,093,256 (GRCm38)	splice site	probably benign
IGL02197:Dmbt1	APN	7	131,085,422 (GRCm38)	splice site	probably benign
IGL02332:Dmbt1	APN	7	131,066,613 (GRCm38)	intron	probably benign
IGL02427:Dmbt1	APN	7	131,088,085 (GRCm38)	splice site	probably null
IGL02726:Dmbt1	APN	7	131,074,410 (GRCm38)	intron	probably benign
IGL02967:Dmbt1	APN	7	131,071,189 (GRCm38)	missense	possibly damaging	0.70
IGL03003:Dmbt1	APN	7	131,082,679 (GRCm38)	missense	probably benign	0.05
IGL03089:Dmbt1	APN	7	131,111,049 (GRCm38)	missense	probably damaging	0.99
cavity	UTSW	7	131,112,236 (GRCm38)	missense	unknown
lacunar	UTSW	7	131,097,631 (GRCm38)	missense	probably damaging	0.97
BB005:Dmbt1	UTSW	7	131,037,890 (GRCm38)	missense	probably benign	0.16
BB015:Dmbt1	UTSW	7	131,037,890 (GRCm38)	missense	probably benign	0.16
H8562:Dmbt1	UTSW	7	131,112,076 (GRCm38)	nonsense	probably null
K3955:Dmbt1	UTSW	7	131,119,564 (GRCm38)	missense	probably damaging	0.98
R0051:Dmbt1	UTSW	7	131,119,496 (GRCm38)	missense	possibly damaging	0.79
R0051:Dmbt1	UTSW	7	131,119,496 (GRCm38)	missense	possibly damaging	0.79
R0257:Dmbt1	UTSW	7	131,106,393 (GRCm38)	missense	probably damaging	1.00
R0388:Dmbt1	UTSW	7	131,096,049 (GRCm38)	splice site	probably benign
R0427:Dmbt1	UTSW	7	131,040,902 (GRCm38)	nonsense	probably null
R0478:Dmbt1	UTSW	7	131,041,187 (GRCm38)	missense	possibly damaging	0.93
R0502:Dmbt1	UTSW	7	131,097,673 (GRCm38)	splice site	probably null
R0538:Dmbt1	UTSW	7	131,049,901 (GRCm38)	splice site	probably benign
R0626:Dmbt1	UTSW	7	131,102,081 (GRCm38)	missense	probably damaging	0.97
R0631:Dmbt1	UTSW	7	131,097,653 (GRCm38)	missense	possibly damaging	0.90
R0948:Dmbt1	UTSW	7	131,093,117 (GRCm38)	missense	possibly damaging	0.95
R1169:Dmbt1	UTSW	7	131,074,524 (GRCm38)	critical splice donor site	probably null
R1413:Dmbt1	UTSW	7	131,050,214 (GRCm38)	missense	probably damaging	1.00
R1458:Dmbt1	UTSW	7	131,044,487 (GRCm38)	splice site	probably benign
R1463:Dmbt1	UTSW	7	131,109,637 (GRCm38)	critical splice donor site	probably null
R1509:Dmbt1	UTSW	7	131,074,331 (GRCm38)	intron	probably benign
R1990:Dmbt1	UTSW	7	131,058,288 (GRCm38)	missense	probably damaging	0.98
R2018:Dmbt1	UTSW	7	131,110,989 (GRCm38)	missense	possibly damaging	0.93
R2019:Dmbt1	UTSW	7	131,110,989 (GRCm38)	missense	possibly damaging	0.93
R2042:Dmbt1	UTSW	7	131,106,359 (GRCm38)	missense	probably damaging	0.99
R2056:Dmbt1	UTSW	7	131,106,170 (GRCm38)	missense	possibly damaging	0.80
R2057:Dmbt1	UTSW	7	131,106,170 (GRCm38)	missense	possibly damaging	0.80
R2058:Dmbt1	UTSW	7	131,106,170 (GRCm38)	missense	possibly damaging	0.80
R2059:Dmbt1	UTSW	7	131,106,170 (GRCm38)	missense	possibly damaging	0.80
R2061:Dmbt1	UTSW	7	131,099,133 (GRCm38)	missense	possibly damaging	0.66
R2092:Dmbt1	UTSW	7	131,050,018 (GRCm38)	missense	probably damaging	1.00
R2102:Dmbt1	UTSW	7	131,102,032 (GRCm38)	missense	probably damaging	0.97
R2155:Dmbt1	UTSW	7	131,097,575 (GRCm38)	missense	possibly damaging	0.66
R2243:Dmbt1	UTSW	7	131,046,562 (GRCm38)	missense	probably benign	0.03
R2256:Dmbt1	UTSW	7	131,090,494 (GRCm38)	missense	probably benign	0.01
R2391:Dmbt1	UTSW	7	131,106,468 (GRCm38)	missense	probably damaging	1.00
R2394:Dmbt1	UTSW	7	131,094,734 (GRCm38)	nonsense	probably null
R3014:Dmbt1	UTSW	7	131,032,097 (GRCm38)	intron	probably benign
R3155:Dmbt1	UTSW	7	131,050,157 (GRCm38)	nonsense	probably null
R3176:Dmbt1	UTSW	7	131,088,071 (GRCm38)	missense	probably benign	0.19
R3276:Dmbt1	UTSW	7	131,088,071 (GRCm38)	missense	probably benign	0.19
R3442:Dmbt1	UTSW	7	131,106,249 (GRCm38)	missense	probably damaging	1.00
R3807:Dmbt1	UTSW	7	131,112,090 (GRCm38)	missense	possibly damaging	0.77
R4060:Dmbt1	UTSW	7	131,074,202 (GRCm38)	intron	probably benign
R4396:Dmbt1	UTSW	7	131,116,632 (GRCm38)	missense	probably damaging	0.98
R4453:Dmbt1	UTSW	7	131,040,934 (GRCm38)	missense	probably damaging	1.00
R5001:Dmbt1	UTSW	7	131,050,012 (GRCm38)	missense	probably damaging	1.00
R5051:Dmbt1	UTSW	7	131,094,742 (GRCm38)	missense	probably benign	0.01
R5156:Dmbt1	UTSW	7	131,097,670 (GRCm38)	critical splice donor site	probably null
R5225:Dmbt1	UTSW	7	131,094,735 (GRCm38)	missense	possibly damaging	0.84
R5281:Dmbt1	UTSW	7	131,082,619 (GRCm38)	missense	probably damaging	1.00
R5308:Dmbt1	UTSW	7	131,041,021 (GRCm38)	missense	probably damaging	1.00
R5447:Dmbt1	UTSW	7	131,119,511 (GRCm38)	missense	probably damaging	0.99
R5467:Dmbt1	UTSW	7	131,040,993 (GRCm38)	missense	probably damaging	1.00
R5497:Dmbt1	UTSW	7	131,063,403 (GRCm38)	intron	probably benign
R5526:Dmbt1	UTSW	7	131,041,190 (GRCm38)	missense	probably damaging	1.00
R5554:Dmbt1	UTSW	7	131,099,300 (GRCm38)	nonsense	probably null
R5566:Dmbt1	UTSW	7	131,106,273 (GRCm38)	missense	probably damaging	1.00
R5595:Dmbt1	UTSW	7	131,054,067 (GRCm38)	missense	probably benign	0.17
R6154:Dmbt1	UTSW	7	131,109,641 (GRCm38)	splice site	probably null
R6188:Dmbt1	UTSW	7	131,097,631 (GRCm38)	missense	probably damaging	0.97
R6214:Dmbt1	UTSW	7	131,066,733 (GRCm38)	missense	possibly damaging	0.95
R6215:Dmbt1	UTSW	7	131,066,733 (GRCm38)	missense	possibly damaging	0.95
R6391:Dmbt1	UTSW	7	131,058,254 (GRCm38)	missense	probably damaging	1.00
R6397:Dmbt1	UTSW	7	131,103,578 (GRCm38)	missense	possibly damaging	0.46
R6436:Dmbt1	UTSW	7	131,116,641 (GRCm38)	missense	probably benign	0.01
R6603:Dmbt1	UTSW	7	131,046,510 (GRCm38)	splice site	probably null
R6719:Dmbt1	UTSW	7	131,119,603 (GRCm38)	missense	possibly damaging	0.83
R6781:Dmbt1	UTSW	7	131,046,561 (GRCm38)	missense	probably benign	0.16
R7148:Dmbt1	UTSW	7	131,066,734 (GRCm38)	nonsense	probably null
R7191:Dmbt1	UTSW	7	131,044,520 (GRCm38)	missense	unknown
R7269:Dmbt1	UTSW	7	131,066,621 (GRCm38)	missense	unknown
R7288:Dmbt1	UTSW	7	131,083,789 (GRCm38)	nonsense	probably null
R7296:Dmbt1	UTSW	7	131,112,132 (GRCm38)	missense	unknown
R7349:Dmbt1	UTSW	7	131,041,124 (GRCm38)	missense	unknown
R7386:Dmbt1	UTSW	7	131,112,236 (GRCm38)	missense	unknown
R7428:Dmbt1	UTSW	7	131,108,463 (GRCm38)	missense	possibly damaging	0.53
R7481:Dmbt1	UTSW	7	131,079,511 (GRCm38)	critical splice acceptor site	probably null
R7486:Dmbt1	UTSW	7	131,066,462 (GRCm38)	missense	unknown
R7513:Dmbt1	UTSW	7	131,090,512 (GRCm38)	missense	unknown
R7567:Dmbt1	UTSW	7	131,061,363 (GRCm38)	splice site	probably null
R7584:Dmbt1	UTSW	7	131,088,751 (GRCm38)	nonsense	probably null
R7736:Dmbt1	UTSW	7	131,116,896 (GRCm38)	missense	unknown
R7758:Dmbt1	UTSW	7	131,121,197 (GRCm38)	missense	unknown
R7928:Dmbt1	UTSW	7	131,037,890 (GRCm38)	missense	probably benign	0.16
R8080:Dmbt1	UTSW	7	131,088,770 (GRCm38)	missense	unknown
R8098:Dmbt1	UTSW	7	131,108,459 (GRCm38)	nonsense	probably null
R8125:Dmbt1	UTSW	7	131,099,223 (GRCm38)	missense	unknown
R8177:Dmbt1	UTSW	7	131,106,432 (GRCm38)	missense	possibly damaging	0.46
R8350:Dmbt1	UTSW	7	131,085,417 (GRCm38)	critical splice donor site	probably null
R8366:Dmbt1	UTSW	7	131,066,600 (GRCm38)	missense	unknown
R8378:Dmbt1	UTSW	7	131,106,465 (GRCm38)	missense	probably damaging	0.96
R8399:Dmbt1	UTSW	7	131,082,587 (GRCm38)	missense	unknown
R8400:Dmbt1	UTSW	7	131,082,587 (GRCm38)	missense	unknown
R8445:Dmbt1	UTSW	7	131,090,380 (GRCm38)	missense	unknown
R8450:Dmbt1	UTSW	7	131,085,417 (GRCm38)	critical splice donor site	probably null
R8511:Dmbt1	UTSW	7	131,102,012 (GRCm38)	missense	unknown
R8688:Dmbt1	UTSW	7	131,058,254 (GRCm38)	missense	unknown
R8850:Dmbt1	UTSW	7	131,090,404 (GRCm38)	missense	unknown
R8852:Dmbt1	UTSW	7	131,041,123 (GRCm38)	missense	unknown
R8871:Dmbt1	UTSW	7	131,116,868 (GRCm38)	missense	unknown
R8943:Dmbt1	UTSW	7	131,119,643 (GRCm38)	missense	possibly damaging	0.68
R8978:Dmbt1	UTSW	7	131,037,881 (GRCm38)	missense	possibly damaging	0.53
R9004:Dmbt1	UTSW	7	131,112,069 (GRCm38)	missense	unknown
R9020:Dmbt1	UTSW	7	131,111,058 (GRCm38)	missense	possibly damaging	0.86
R9088:Dmbt1	UTSW	7	131,116,689 (GRCm38)	missense	unknown
R9230:Dmbt1	UTSW	7	131,037,912 (GRCm38)	missense	probably benign	0.01
R9304:Dmbt1	UTSW	7	131,099,125 (GRCm38)	missense	unknown
R9377:Dmbt1	UTSW	7	131,093,102 (GRCm38)	missense	unknown
R9428:Dmbt1	UTSW	7	131,066,478 (GRCm38)	missense	unknown
R9474:Dmbt1	UTSW	7	131,074,257 (GRCm38)	missense	unknown
R9573:Dmbt1	UTSW	7	131,056,180 (GRCm38)	critical splice donor site	probably null
R9675:Dmbt1	UTSW	7	131,110,923 (GRCm38)	missense	probably damaging	0.98
R9689:Dmbt1	UTSW	7	131,058,285 (GRCm38)	missense	unknown
R9781:Dmbt1	UTSW	7	131,037,869 (GRCm38)	missense	probably benign	0.00
X0024:Dmbt1	UTSW	7	131,112,248 (GRCm38)	nonsense	probably null
X0062:Dmbt1	UTSW	7	131,094,851 (GRCm38)	missense	possibly damaging	0.81
Z1176:Dmbt1	UTSW	7	131,088,812 (GRCm38)	missense	unknown
Z1177:Dmbt1	UTSW	7	131,082,485 (GRCm38)	critical splice acceptor site	probably null

Predicted Primers

PCR Primer
(F):5'- CCATGGGTAGCATCTTCCTG -3'
(R):5'- GCAAAATGGATTAAGTGCTGCAC -3'

Sequencing Primer
(F):5'- CCTGGCATTGTGTATGGTCACAC -3'
(R):5'- GATTAAGTGCTGCACCTCTCAGATG -3'

Posted On

2019-10-17