Incidental Mutation 'R7559:Helz'
| ID |
584968 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Helz
|
| Ensembl Gene |
ENSMUSG00000020721 |
| Gene Name |
helicase with zinc finger domain |
| Synonyms |
3110078M01Rik, 9430093I07Rik, 9630002H22Rik |
| MMRRC Submission |
045653-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7559 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
107438756-107584652 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 107491104 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Threonine
at position 162
(S162T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000074533
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000075012]
[ENSMUST00000100305]
[ENSMUST00000106746]
|
| AlphaFold |
Q6DFV5 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000075012
AA Change: S162T
PolyPhen 2
Score 0.670 (Sensitivity: 0.86; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000074533
Gene: ENSMUSG00000020721
AA Change: S162T
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1ihga1
|
6 |
84 |
5e-3 |
SMART |
|
low complexity region
|
129 |
146 |
N/A |
INTRINSIC |
|
ZnF_C3H1
|
178 |
205 |
2.61e-4 |
SMART |
|
Pfam:ResIII
|
639 |
807 |
6.7e-8 |
PFAM |
|
Pfam:AAA_11
|
641 |
768 |
2.3e-14 |
PFAM |
|
Pfam:AAA_30
|
641 |
838 |
2.6e-11 |
PFAM |
|
Pfam:AAA_19
|
648 |
729 |
5.5e-11 |
PFAM |
|
Pfam:AAA_11
|
758 |
834 |
3.8e-18 |
PFAM |
|
Pfam:AAA_12
|
841 |
1053 |
7.4e-38 |
PFAM |
|
low complexity region
|
1165 |
1176 |
N/A |
INTRINSIC |
|
low complexity region
|
1360 |
1448 |
N/A |
INTRINSIC |
|
low complexity region
|
1466 |
1487 |
N/A |
INTRINSIC |
|
low complexity region
|
1557 |
1568 |
N/A |
INTRINSIC |
|
low complexity region
|
1631 |
1647 |
N/A |
INTRINSIC |
|
low complexity region
|
1716 |
1736 |
N/A |
INTRINSIC |
|
low complexity region
|
1926 |
1933 |
N/A |
INTRINSIC |
|
low complexity region
|
1942 |
1957 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000100305
AA Change: S162T
PolyPhen 2
Score 0.294 (Sensitivity: 0.91; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000097878
Gene: ENSMUSG00000020721
AA Change: S162T
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1ihga1
|
6 |
84 |
5e-3 |
SMART |
|
low complexity region
|
129 |
146 |
N/A |
INTRINSIC |
|
ZnF_C3H1
|
178 |
205 |
2.61e-4 |
SMART |
|
Pfam:AAA_11
|
641 |
833 |
2.7e-31 |
PFAM |
|
Pfam:AAA_30
|
641 |
837 |
1.7e-10 |
PFAM |
|
Pfam:AAA_19
|
648 |
727 |
6.3e-9 |
PFAM |
|
Pfam:AAA_12
|
840 |
1052 |
3.4e-36 |
PFAM |
|
low complexity region
|
1164 |
1175 |
N/A |
INTRINSIC |
|
low complexity region
|
1359 |
1447 |
N/A |
INTRINSIC |
|
low complexity region
|
1465 |
1486 |
N/A |
INTRINSIC |
|
low complexity region
|
1556 |
1567 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000106746
AA Change: S162T
PolyPhen 2
Score 0.670 (Sensitivity: 0.86; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000102357
Gene: ENSMUSG00000020721
AA Change: S162T
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1ihga1
|
6 |
84 |
5e-3 |
SMART |
|
low complexity region
|
129 |
146 |
N/A |
INTRINSIC |
|
ZnF_C3H1
|
178 |
205 |
2.61e-4 |
SMART |
|
Pfam:AAA_11
|
641 |
833 |
1e-31 |
PFAM |
|
Pfam:AAA_30
|
641 |
837 |
8.3e-11 |
PFAM |
|
Pfam:AAA_19
|
648 |
727 |
2.2e-9 |
PFAM |
|
Pfam:AAA_12
|
840 |
1052 |
1.7e-36 |
PFAM |
|
low complexity region
|
1164 |
1175 |
N/A |
INTRINSIC |
|
low complexity region
|
1359 |
1447 |
N/A |
INTRINSIC |
|
low complexity region
|
1465 |
1486 |
N/A |
INTRINSIC |
|
low complexity region
|
1556 |
1567 |
N/A |
INTRINSIC |
|
low complexity region
|
1630 |
1646 |
N/A |
INTRINSIC |
|
low complexity region
|
1715 |
1735 |
N/A |
INTRINSIC |
|
low complexity region
|
1925 |
1932 |
N/A |
INTRINSIC |
|
low complexity region
|
1941 |
1956 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.0568 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.9%
|
| Validation Efficiency |
99% (68/69) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] HELZ is a member of the superfamily I class of RNA helicases. RNA helicases alter the conformation of RNA by unwinding double-stranded regions, thereby altering the biologic activity of the RNA molecule and regulating access to other proteins (Wagner et al., 1999 [PubMed 10471385]).[supplied by OMIM, Mar 2008]
PHENOTYPE: Mice homozygous for a gene-trapped allele are viable, fertile and phenotypically normal with no apparent skeletal defects. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 72 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adap1 |
C |
A |
5: 139,265,295 (GRCm39) |
R206L |
probably damaging |
Het |
| Adcy3 |
A |
G |
12: 4,248,440 (GRCm39) |
K501E |
probably benign |
Het |
| Agl |
T |
C |
3: 116,545,764 (GRCm39) |
D679G |
|
Het |
| Ankrd10 |
A |
T |
8: 11,662,548 (GRCm39) |
V395D |
probably damaging |
Het |
| Ano5 |
A |
G |
7: 51,224,636 (GRCm39) |
I531V |
probably damaging |
Het |
| Apol9a |
T |
A |
15: 77,288,761 (GRCm39) |
H202L |
possibly damaging |
Het |
| Atp6v1c2 |
A |
C |
12: 17,351,215 (GRCm39) |
I105M |
probably benign |
Het |
| Cfap57 |
C |
T |
4: 118,472,128 (GRCm39) |
V84I |
probably benign |
Het |
| Coro1b |
T |
C |
19: 4,200,220 (GRCm39) |
|
probably null |
Het |
| D930020B18Rik |
A |
G |
10: 121,492,131 (GRCm39) |
|
probably benign |
Het |
| Dcst2 |
T |
C |
3: 89,276,021 (GRCm39) |
F384S |
possibly damaging |
Het |
| Ddx39a |
T |
A |
8: 84,447,595 (GRCm39) |
F147I |
possibly damaging |
Het |
| Drosha |
A |
G |
15: 12,842,508 (GRCm39) |
E393G |
probably damaging |
Het |
| Etfdh |
T |
C |
3: 79,530,886 (GRCm39) |
Y45C |
probably damaging |
Het |
| Fam20c |
G |
T |
5: 138,778,954 (GRCm39) |
E287D |
possibly damaging |
Het |
| Flnc |
T |
A |
6: 29,459,009 (GRCm39) |
D2463E |
probably damaging |
Het |
| Flt4 |
A |
T |
11: 49,535,198 (GRCm39) |
I1209F |
possibly damaging |
Het |
| Foxp1 |
T |
C |
6: 98,922,521 (GRCm39) |
D437G |
unknown |
Het |
| Fras1 |
T |
C |
5: 96,888,713 (GRCm39) |
V2753A |
possibly damaging |
Het |
| Ftsj3 |
T |
C |
11: 106,143,813 (GRCm39) |
D277G |
possibly damaging |
Het |
| Gad1 |
T |
C |
2: 70,394,256 (GRCm39) |
|
probably null |
Het |
| Gal3st2c |
A |
G |
1: 93,937,075 (GRCm39) |
Y340C |
probably damaging |
Het |
| Gbp9 |
A |
G |
5: 105,232,975 (GRCm39) |
F226L |
probably damaging |
Het |
| Gm11992 |
C |
T |
11: 9,002,747 (GRCm39) |
P37S |
possibly damaging |
Het |
| Gm19668 |
G |
T |
10: 77,634,572 (GRCm39) |
C132* |
probably null |
Het |
| Hdac3 |
A |
T |
18: 38,078,569 (GRCm39) |
F139I |
possibly damaging |
Het |
| Hectd4 |
A |
G |
5: 121,453,573 (GRCm39) |
|
probably null |
Het |
| Hspb6 |
C |
A |
7: 30,253,712 (GRCm39) |
S75Y |
probably damaging |
Het |
| Il17rb |
T |
A |
14: 29,719,000 (GRCm39) |
I361F |
probably damaging |
Het |
| Iqsec3 |
A |
T |
6: 121,364,739 (GRCm39) |
V850D |
probably damaging |
Het |
| Knl1 |
A |
G |
2: 118,924,487 (GRCm39) |
E1840G |
possibly damaging |
Het |
| Lamc3 |
A |
G |
2: 31,812,380 (GRCm39) |
K939R |
probably benign |
Het |
| Lmo7 |
C |
T |
14: 102,124,662 (GRCm39) |
R496* |
probably null |
Het |
| Lsm14a |
A |
T |
7: 34,052,826 (GRCm39) |
C374* |
probably null |
Het |
| Luc7l |
T |
C |
17: 26,474,089 (GRCm39) |
L49P |
probably damaging |
Het |
| Mdga2 |
A |
C |
12: 66,520,003 (GRCm39) |
C988G |
probably damaging |
Het |
| Mtf1 |
T |
C |
4: 124,713,999 (GRCm39) |
V136A |
probably damaging |
Het |
| Myo7b |
T |
A |
18: 32,116,413 (GRCm39) |
I1016F |
probably benign |
Het |
| Nadsyn1 |
C |
A |
7: 143,361,804 (GRCm39) |
A306S |
probably benign |
Het |
| Naip5 |
T |
C |
13: 100,356,204 (GRCm39) |
Q1137R |
probably benign |
Het |
| Naip5 |
G |
T |
13: 100,356,205 (GRCm39) |
Q1137K |
not run |
Het |
| Nr4a1 |
T |
C |
15: 101,168,780 (GRCm39) |
V272A |
probably damaging |
Het |
| Opcml |
A |
T |
9: 28,814,620 (GRCm39) |
T291S |
probably benign |
Het |
| Or13a24 |
T |
A |
7: 140,154,356 (GRCm39) |
C97S |
probably damaging |
Het |
| Or52u1 |
C |
A |
7: 104,237,087 (GRCm39) |
H25Q |
probably damaging |
Het |
| Or56b1b |
C |
T |
7: 108,164,763 (GRCm39) |
A80T |
probably damaging |
Het |
| Osbp2 |
C |
G |
11: 3,662,493 (GRCm39) |
K196N |
probably damaging |
Het |
| Otoa |
T |
C |
7: 120,743,149 (GRCm39) |
V792A |
probably damaging |
Het |
| Pcmtd1 |
A |
G |
1: 7,239,766 (GRCm39) |
D245G |
probably damaging |
Het |
| Pcnx1 |
T |
C |
12: 82,039,896 (GRCm39) |
V1428A |
unknown |
Het |
| Pik3r4 |
A |
G |
9: 105,555,352 (GRCm39) |
H1103R |
probably benign |
Het |
| Pjvk |
C |
T |
2: 76,486,154 (GRCm39) |
H185Y |
probably benign |
Het |
| Pkd1l3 |
T |
C |
8: 110,351,072 (GRCm39) |
V639A |
probably benign |
Het |
| Pklr |
T |
C |
3: 89,050,365 (GRCm39) |
S405P |
probably damaging |
Het |
| Pla2g12a |
T |
A |
3: 129,672,569 (GRCm39) |
Y68N |
probably damaging |
Het |
| Proz |
A |
G |
8: 13,113,455 (GRCm39) |
H92R |
probably benign |
Het |
| Sec23ip |
G |
T |
7: 128,379,074 (GRCm39) |
V844F |
possibly damaging |
Het |
| Sema3f |
A |
G |
9: 107,561,777 (GRCm39) |
V520A |
possibly damaging |
Het |
| Serpinb12 |
A |
G |
1: 106,881,453 (GRCm39) |
I197V |
probably damaging |
Het |
| Sim2 |
A |
T |
16: 93,910,218 (GRCm39) |
I207F |
possibly damaging |
Het |
| Slc15a2 |
C |
T |
16: 36,572,259 (GRCm39) |
V702I |
probably benign |
Het |
| Slc35f4 |
T |
C |
14: 49,541,732 (GRCm39) |
I341V |
probably benign |
Het |
| Spam1 |
A |
G |
6: 24,800,452 (GRCm39) |
Y397C |
probably damaging |
Het |
| Spire1 |
A |
T |
18: 67,634,187 (GRCm39) |
M417K |
probably benign |
Het |
| Srcap |
T |
C |
7: 127,129,722 (GRCm39) |
S515P |
unknown |
Het |
| Tfrc |
T |
A |
16: 32,440,235 (GRCm39) |
|
probably null |
Het |
| Topors |
A |
G |
4: 40,261,401 (GRCm39) |
S628P |
unknown |
Het |
| Trim71 |
T |
C |
9: 114,342,110 (GRCm39) |
Y724C |
probably damaging |
Het |
| Ttn |
C |
T |
2: 76,623,199 (GRCm39) |
V15413I |
probably damaging |
Het |
| Vmn1r21 |
A |
T |
6: 57,821,227 (GRCm39) |
N72K |
probably damaging |
Het |
| Vmn2r80 |
A |
T |
10: 79,030,459 (GRCm39) |
M762L |
probably benign |
Het |
| Wdr62 |
A |
G |
7: 29,970,198 (GRCm39) |
I203T |
probably damaging |
Het |
|
| Other mutations in Helz |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00971:Helz
|
APN |
11 |
107,554,479 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL01419:Helz
|
APN |
11 |
107,577,340 (GRCm39) |
missense |
unknown |
|
|
IGL01864:Helz
|
APN |
11 |
107,493,180 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01999:Helz
|
APN |
11 |
107,493,754 (GRCm39) |
splice site |
probably benign |
|
|
IGL02938:Helz
|
APN |
11 |
107,577,264 (GRCm39) |
missense |
unknown |
|
|
IGL03157:Helz
|
APN |
11 |
107,468,714 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL03374:Helz
|
APN |
11 |
107,510,973 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0058:Helz
|
UTSW |
11 |
107,563,384 (GRCm39) |
unclassified |
probably benign |
|
|
R0058:Helz
|
UTSW |
11 |
107,563,384 (GRCm39) |
unclassified |
probably benign |
|
|
R0112:Helz
|
UTSW |
11 |
107,563,774 (GRCm39) |
unclassified |
probably benign |
|
|
R0243:Helz
|
UTSW |
11 |
107,528,740 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R0328:Helz
|
UTSW |
11 |
107,495,174 (GRCm39) |
missense |
probably benign |
0.30 |
|
R0578:Helz
|
UTSW |
11 |
107,577,226 (GRCm39) |
missense |
unknown |
|
|
R0928:Helz
|
UTSW |
11 |
107,517,519 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1428:Helz
|
UTSW |
11 |
107,483,666 (GRCm39) |
splice site |
probably benign |
|
|
R1493:Helz
|
UTSW |
11 |
107,504,751 (GRCm39) |
missense |
probably benign |
0.15 |
|
R1494:Helz
|
UTSW |
11 |
107,494,889 (GRCm39) |
splice site |
probably benign |
|
|
R1541:Helz
|
UTSW |
11 |
107,560,874 (GRCm39) |
missense |
probably benign |
0.39 |
|
R1619:Helz
|
UTSW |
11 |
107,527,105 (GRCm39) |
nonsense |
probably null |
|
|
R1809:Helz
|
UTSW |
11 |
107,489,997 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R1942:Helz
|
UTSW |
11 |
107,493,318 (GRCm39) |
missense |
probably benign |
0.20 |
|
R2095:Helz
|
UTSW |
11 |
107,536,972 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2133:Helz
|
UTSW |
11 |
107,561,310 (GRCm39) |
missense |
unknown |
|
|
R2167:Helz
|
UTSW |
11 |
107,563,790 (GRCm39) |
unclassified |
probably benign |
|
|
R2406:Helz
|
UTSW |
11 |
107,577,378 (GRCm39) |
missense |
unknown |
|
|
R2571:Helz
|
UTSW |
11 |
107,504,778 (GRCm39) |
missense |
probably benign |
0.05 |
|
R2858:Helz
|
UTSW |
11 |
107,563,753 (GRCm39) |
unclassified |
probably benign |
|
|
R3927:Helz
|
UTSW |
11 |
107,576,118 (GRCm39) |
missense |
unknown |
|
|
R4449:Helz
|
UTSW |
11 |
107,494,989 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4453:Helz
|
UTSW |
11 |
107,563,455 (GRCm39) |
nonsense |
probably null |
|
|
R4583:Helz
|
UTSW |
11 |
107,536,895 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4684:Helz
|
UTSW |
11 |
107,539,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4714:Helz
|
UTSW |
11 |
107,517,542 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4875:Helz
|
UTSW |
11 |
107,528,560 (GRCm39) |
intron |
probably benign |
|
|
R4924:Helz
|
UTSW |
11 |
107,493,165 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4930:Helz
|
UTSW |
11 |
107,510,994 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5078:Helz
|
UTSW |
11 |
107,546,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5446:Helz
|
UTSW |
11 |
107,523,030 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5535:Helz
|
UTSW |
11 |
107,536,946 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5650:Helz
|
UTSW |
11 |
107,485,972 (GRCm39) |
missense |
probably null |
0.96 |
|
R5714:Helz
|
UTSW |
11 |
107,517,347 (GRCm39) |
splice site |
probably null |
|
|
R5784:Helz
|
UTSW |
11 |
107,561,307 (GRCm39) |
missense |
unknown |
|
|
R5998:Helz
|
UTSW |
11 |
107,576,360 (GRCm39) |
nonsense |
probably null |
|
|
R6042:Helz
|
UTSW |
11 |
107,504,946 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6089:Helz
|
UTSW |
11 |
107,485,963 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6137:Helz
|
UTSW |
11 |
107,509,886 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R6373:Helz
|
UTSW |
11 |
107,486,010 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6392:Helz
|
UTSW |
11 |
107,493,167 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R6618:Helz
|
UTSW |
11 |
107,489,976 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6644:Helz
|
UTSW |
11 |
107,523,087 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R6811:Helz
|
UTSW |
11 |
107,510,144 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6874:Helz
|
UTSW |
11 |
107,554,460 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6911:Helz
|
UTSW |
11 |
107,510,051 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7039:Helz
|
UTSW |
11 |
107,510,144 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7061:Helz
|
UTSW |
11 |
107,540,003 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7438:Helz
|
UTSW |
11 |
107,552,856 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7464:Helz
|
UTSW |
11 |
107,527,104 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7513:Helz
|
UTSW |
11 |
107,546,941 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7734:Helz
|
UTSW |
11 |
107,576,248 (GRCm39) |
missense |
unknown |
|
|
R7780:Helz
|
UTSW |
11 |
107,528,689 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7982:Helz
|
UTSW |
11 |
107,517,456 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R8024:Helz
|
UTSW |
11 |
107,577,247 (GRCm39) |
missense |
unknown |
|
|
R8181:Helz
|
UTSW |
11 |
107,563,399 (GRCm39) |
missense |
unknown |
|
|
R8346:Helz
|
UTSW |
11 |
107,563,399 (GRCm39) |
missense |
unknown |
|
|
R8729:Helz
|
UTSW |
11 |
107,528,754 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8807:Helz
|
UTSW |
11 |
107,493,835 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8821:Helz
|
UTSW |
11 |
107,525,919 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8891:Helz
|
UTSW |
11 |
107,552,842 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8909:Helz
|
UTSW |
11 |
107,556,834 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8922:Helz
|
UTSW |
11 |
107,539,985 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8926:Helz
|
UTSW |
11 |
107,563,509 (GRCm39) |
missense |
unknown |
|
|
R8988:Helz
|
UTSW |
11 |
107,495,079 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9053:Helz
|
UTSW |
11 |
107,563,761 (GRCm39) |
missense |
unknown |
|
|
R9056:Helz
|
UTSW |
11 |
107,547,019 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R9099:Helz
|
UTSW |
11 |
107,523,041 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9122:Helz
|
UTSW |
11 |
107,556,830 (GRCm39) |
missense |
probably benign |
0.17 |
|
R9194:Helz
|
UTSW |
11 |
107,561,113 (GRCm39) |
nonsense |
probably null |
|
|
R9220:Helz
|
UTSW |
11 |
107,560,873 (GRCm39) |
missense |
probably benign |
0.11 |
|
R9223:Helz
|
UTSW |
11 |
107,509,918 (GRCm39) |
missense |
probably benign |
0.17 |
|
R9242:Helz
|
UTSW |
11 |
107,523,153 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9644:Helz
|
UTSW |
11 |
107,563,687 (GRCm39) |
missense |
unknown |
|
|
R9761:Helz
|
UTSW |
11 |
107,560,874 (GRCm39) |
nonsense |
probably null |
|
|
X0065:Helz
|
UTSW |
11 |
107,561,273 (GRCm39) |
missense |
unknown |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GCTAATGGCCTCTGTCAACAG -3'
(R):5'- ATAATACCATGGGTTTGACGTTGAC -3'
Sequencing Primer
(F):5'- CTGTCAACAGAGAATTTAGCTGCTGG -3'
(R):5'- CTTCTGCTGCAAATAGGAAATAAGCC -3'
|
| Posted On |
2019-10-17 |
Incidental Mutation