Incidental Mutation 'R7571:Abca16'
| ID |
585832 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Abca16
|
| Ensembl Gene |
ENSMUSG00000051900 |
| Gene Name |
ATP-binding cassette, sub-family A member 16 |
| Synonyms |
|
| MMRRC Submission |
045711-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7571 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
7 |
| Chromosomal Location |
120008870-120144036 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 120119211 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Isoleucine
at position 985
(N985I)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000112736
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000056042]
[ENSMUST00000120490]
|
| AlphaFold |
E9PWJ7 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000056042
AA Change: N984I
PolyPhen 2
Score 0.373 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000061094
Gene: ENSMUSG00000051900
AA Change: N984I
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ABC2_membrane_3
|
26 |
455 |
2.7e-23 |
PFAM |
|
AAA
|
537 |
720 |
2.01e-7 |
SMART |
|
Pfam:ABC2_membrane_3
|
898 |
1287 |
4.6e-25 |
PFAM |
|
low complexity region
|
1325 |
1336 |
N/A |
INTRINSIC |
|
low complexity region
|
1342 |
1353 |
N/A |
INTRINSIC |
|
AAA
|
1378 |
1563 |
4.23e-6 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000120490
AA Change: N985I
PolyPhen 2
Score 0.114 (Sensitivity: 0.93; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000112736
Gene: ENSMUSG00000051900
AA Change: N985I
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ABC2_membrane_3
|
25 |
456 |
2.4e-22 |
PFAM |
|
AAA
|
538 |
721 |
2.01e-7 |
SMART |
|
Pfam:ABC2_membrane_3
|
899 |
1288 |
1.1e-27 |
PFAM |
|
low complexity region
|
1326 |
1337 |
N/A |
INTRINSIC |
|
low complexity region
|
1343 |
1354 |
N/A |
INTRINSIC |
|
AAA
|
1379 |
1564 |
4.23e-6 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.8%
- 20x: 99.4%
|
| Validation Efficiency |
|
| Allele List at MGI |
All alleles(4) : Targeted(3) Gene trapped(1)
|
| Other mutations in this stock |
Total: 112 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abi3bp |
T |
A |
16: 56,451,345 (GRCm39) |
|
probably null |
Het |
| Acad12 |
A |
T |
5: 121,745,257 (GRCm39) |
Y309* |
probably null |
Het |
| Acadsb |
G |
T |
7: 131,045,283 (GRCm39) |
R405L |
probably damaging |
Het |
| Acan |
G |
A |
7: 78,736,015 (GRCm39) |
V154M |
probably damaging |
Het |
| Adam22 |
G |
A |
5: 8,132,160 (GRCm39) |
R894* |
probably null |
Het |
| Ahnak |
A |
T |
19: 8,978,150 (GRCm39) |
K90* |
probably null |
Het |
| Ak4 |
T |
C |
4: 101,317,739 (GRCm39) |
I103T |
probably benign |
Het |
| Ap4e1 |
C |
T |
2: 126,861,256 (GRCm39) |
L132F |
probably damaging |
Het |
| Apol7b |
C |
T |
15: 77,307,677 (GRCm39) |
V273I |
probably benign |
Het |
| Arhgef37 |
T |
A |
18: 61,637,403 (GRCm39) |
I420F |
probably damaging |
Het |
| Atg13 |
C |
T |
2: 91,510,687 (GRCm39) |
|
probably null |
Het |
| Bach1 |
G |
A |
16: 87,516,179 (GRCm39) |
R240Q |
probably benign |
Het |
| Cabin1 |
A |
T |
10: 75,482,500 (GRCm39) |
S2148T |
probably damaging |
Het |
| Cacna1i |
T |
C |
15: 80,259,537 (GRCm39) |
V1269A |
probably damaging |
Het |
| Cdipt |
T |
C |
7: 126,578,794 (GRCm39) |
I195T |
probably benign |
Het |
| Ces2b |
A |
T |
8: 105,561,641 (GRCm39) |
H245L |
probably damaging |
Het |
| Cimip2c |
A |
T |
5: 30,639,502 (GRCm39) |
E143V |
possibly damaging |
Het |
| Clstn1 |
T |
G |
4: 149,730,744 (GRCm39) |
M825R |
probably benign |
Het |
| Cntn3 |
G |
A |
6: 102,255,364 (GRCm39) |
T178I |
probably damaging |
Het |
| Col7a1 |
A |
G |
9: 108,811,775 (GRCm39) |
M2789V |
probably null |
Het |
| Col9a2 |
A |
T |
4: 120,896,981 (GRCm39) |
I24F |
unknown |
Het |
| Cpne2 |
T |
C |
8: 95,278,408 (GRCm39) |
M134T |
probably benign |
Het |
| Cpt1b |
A |
G |
15: 89,305,546 (GRCm39) |
|
probably null |
Het |
| Crocc |
T |
C |
4: 140,773,360 (GRCm39) |
|
probably null |
Het |
| Cts8 |
T |
C |
13: 61,395,981 (GRCm39) |
Y330C |
probably damaging |
Het |
| Cwc22 |
T |
C |
2: 77,747,411 (GRCm39) |
D434G |
probably benign |
Het |
| Cyp3a13 |
T |
C |
5: 137,897,125 (GRCm39) |
I396M |
possibly damaging |
Het |
| Ddr2 |
A |
T |
1: 169,829,420 (GRCm39) |
I278N |
probably benign |
Het |
| Dnaaf5 |
A |
G |
5: 139,155,963 (GRCm39) |
E548G |
possibly damaging |
Het |
| Dync2h1 |
A |
G |
9: 7,002,623 (GRCm39) |
L3808P |
probably damaging |
Het |
| Faf2 |
T |
A |
13: 54,798,027 (GRCm39) |
W209R |
probably damaging |
Het |
| Fbln2 |
A |
T |
6: 91,245,557 (GRCm39) |
E992D |
probably damaging |
Het |
| Fdxacb1 |
T |
A |
9: 50,683,093 (GRCm39) |
V352D |
probably damaging |
Het |
| Flg2 |
G |
T |
3: 93,127,303 (GRCm39) |
G2072* |
probably null |
Het |
| Flii |
A |
T |
11: 60,611,962 (GRCm39) |
L347Q |
probably damaging |
Het |
| Fndc3a |
A |
T |
14: 72,827,336 (GRCm39) |
H116Q |
probably damaging |
Het |
| Fnta |
A |
T |
8: 26,505,493 (GRCm39) |
M39K |
probably benign |
Het |
| Gabra4 |
A |
G |
5: 71,729,335 (GRCm39) |
S482P |
probably benign |
Het |
| Gapdhs |
G |
A |
7: 30,437,383 (GRCm39) |
P61S |
unknown |
Het |
| Gm10153 |
A |
T |
7: 141,743,401 (GRCm39) |
C242* |
probably null |
Het |
| Gp1ba |
A |
G |
11: 70,530,920 (GRCm39) |
I229V |
unknown |
Het |
| Grap2 |
T |
A |
15: 80,527,905 (GRCm39) |
L117Q |
probably damaging |
Het |
| Grik5 |
A |
G |
7: 24,713,310 (GRCm39) |
I766T |
possibly damaging |
Het |
| Hrh3 |
A |
T |
2: 179,743,079 (GRCm39) |
I183N |
probably damaging |
Het |
| Htr5a |
C |
A |
5: 28,047,893 (GRCm39) |
Y149* |
probably null |
Het |
| Ibtk |
T |
C |
9: 85,604,353 (GRCm39) |
I527V |
probably benign |
Het |
| Il33 |
T |
A |
19: 29,934,341 (GRCm39) |
S184R |
probably damaging |
Het |
| Kansl3 |
T |
A |
1: 36,404,668 (GRCm39) |
Q94L |
possibly damaging |
Het |
| Katnip |
C |
T |
7: 125,307,193 (GRCm39) |
|
probably benign |
Het |
| Kcnh6 |
A |
G |
11: 105,908,242 (GRCm39) |
D286G |
probably benign |
Het |
| Kmt2e |
T |
A |
5: 23,683,585 (GRCm39) |
M281K |
probably damaging |
Het |
| Lrp2 |
T |
A |
2: 69,346,747 (GRCm39) |
H833L |
probably damaging |
Het |
| Meis1 |
A |
T |
11: 18,891,702 (GRCm39) |
V282E |
probably damaging |
Het |
| Mfsd8 |
T |
G |
3: 40,785,097 (GRCm39) |
D240A |
probably damaging |
Het |
| Muc5b |
A |
G |
7: 141,400,986 (GRCm39) |
T534A |
unknown |
Het |
| Myo18b |
G |
A |
5: 112,978,194 (GRCm39) |
L1243F |
probably damaging |
Het |
| Nefl |
A |
G |
14: 68,322,123 (GRCm39) |
I238V |
probably benign |
Het |
| Nexn |
T |
A |
3: 151,959,284 (GRCm39) |
I62F |
possibly damaging |
Het |
| Niban1 |
T |
C |
1: 151,594,048 (GRCm39) |
V911A |
probably benign |
Het |
| Notch4 |
T |
C |
17: 34,802,548 (GRCm39) |
L1323P |
probably damaging |
Het |
| Or51h1 |
T |
C |
7: 102,308,258 (GRCm39) |
S77P |
probably damaging |
Het |
| Or5p68 |
A |
T |
7: 107,945,689 (GRCm39) |
F166L |
probably benign |
Het |
| Or8b1 |
T |
C |
9: 38,399,952 (GRCm39) |
V209A |
probably benign |
Het |
| Patj |
C |
A |
4: 98,457,217 (GRCm39) |
H1244N |
probably damaging |
Het |
| Peg10 |
T |
A |
6: 4,756,082 (GRCm39) |
D219E |
unknown |
Het |
| Pi4kb |
G |
T |
3: 94,906,425 (GRCm39) |
|
probably null |
Het |
| Piezo1 |
A |
G |
8: 123,225,157 (GRCm39) |
F614S |
|
Het |
| Pisd |
T |
A |
5: 32,894,681 (GRCm39) |
N372Y |
probably damaging |
Het |
| Piwil4 |
T |
C |
9: 14,645,893 (GRCm39) |
D178G |
probably benign |
Het |
| Plekho1 |
G |
T |
3: 95,896,566 (GRCm39) |
P301Q |
probably damaging |
Het |
| Pop1 |
T |
A |
15: 34,529,093 (GRCm39) |
W738R |
probably null |
Het |
| Ppp4r1 |
C |
T |
17: 66,117,611 (GRCm39) |
P125L |
possibly damaging |
Het |
| Pramel48 |
A |
T |
5: 95,630,819 (GRCm39) |
N232I |
probably damaging |
Het |
| Prdm9 |
T |
A |
17: 15,783,526 (GRCm39) |
N13I |
probably damaging |
Het |
| Psd4 |
T |
G |
2: 24,297,023 (GRCm39) |
V932G |
probably damaging |
Het |
| Ptger3 |
T |
C |
3: 157,347,412 (GRCm39) |
S355P |
probably benign |
Het |
| Ptprb |
T |
C |
10: 116,175,335 (GRCm39) |
V823A |
probably damaging |
Het |
| Ptprj |
C |
T |
2: 90,285,530 (GRCm39) |
V841I |
probably benign |
Het |
| Ranbp3 |
T |
C |
17: 57,014,923 (GRCm39) |
S281P |
probably benign |
Het |
| Rasal3 |
T |
A |
17: 32,614,835 (GRCm39) |
M541L |
possibly damaging |
Het |
| Rassf1 |
A |
G |
9: 107,428,982 (GRCm39) |
T63A |
possibly damaging |
Het |
| Rcor3 |
C |
A |
1: 191,822,173 (GRCm39) |
G8V |
probably damaging |
Het |
| Rgs4 |
G |
A |
1: 169,571,927 (GRCm39) |
T124I |
probably damaging |
Het |
| Rspo2 |
T |
A |
15: 43,033,372 (GRCm39) |
|
probably benign |
Het |
| Scgn |
T |
C |
13: 24,137,897 (GRCm39) |
D258G |
probably damaging |
Het |
| Shkbp1 |
A |
G |
7: 27,046,556 (GRCm39) |
S403P |
possibly damaging |
Het |
| Slc25a13 |
A |
G |
6: 6,052,785 (GRCm39) |
L525P |
probably damaging |
Het |
| Snd1 |
G |
T |
6: 28,526,202 (GRCm39) |
K193N |
possibly damaging |
Het |
| Sntg2 |
C |
T |
12: 30,225,201 (GRCm39) |
A516T |
probably damaging |
Het |
| Stard13 |
A |
G |
5: 150,982,967 (GRCm39) |
I699T |
probably damaging |
Het |
| Svil |
T |
A |
18: 5,114,636 (GRCm39) |
V1984D |
probably damaging |
Het |
| Swt1 |
A |
G |
1: 151,270,470 (GRCm39) |
S582P |
probably benign |
Het |
| Sypl2 |
A |
G |
3: 108,121,854 (GRCm39) |
*265Q |
probably null |
Het |
| Taar8a |
T |
A |
10: 23,953,306 (GRCm39) |
Y303* |
probably null |
Het |
| Tasor2 |
T |
C |
13: 3,625,292 (GRCm39) |
T1553A |
probably benign |
Het |
| Tlr2 |
T |
A |
3: 83,743,849 (GRCm39) |
I745F |
probably damaging |
Het |
| Tnrc6b |
A |
G |
15: 80,813,594 (GRCm39) |
T1784A |
probably benign |
Het |
| Tpo |
C |
A |
12: 30,169,431 (GRCm39) |
M101I |
probably benign |
Het |
| Trpm2 |
G |
T |
10: 77,773,784 (GRCm39) |
R544S |
probably benign |
Het |
| Ttc14 |
A |
G |
3: 33,863,400 (GRCm39) |
R603G |
unknown |
Het |
| Tubgcp6 |
A |
C |
15: 88,984,925 (GRCm39) |
V1694G |
probably damaging |
Het |
| Uba6 |
C |
A |
5: 86,294,970 (GRCm39) |
K356N |
probably benign |
Het |
| Usp16 |
T |
C |
16: 87,261,723 (GRCm39) |
V113A |
possibly damaging |
Het |
| Vcam1 |
G |
A |
3: 115,908,032 (GRCm39) |
Q677* |
probably null |
Het |
| Vmn1r238 |
T |
A |
18: 3,122,721 (GRCm39) |
E231V |
probably damaging |
Het |
| Vmn1r70 |
T |
C |
7: 10,367,871 (GRCm39) |
F120L |
probably benign |
Het |
| Vmn2r116 |
T |
A |
17: 23,603,830 (GRCm39) |
|
probably null |
Het |
| Vmn2r5 |
A |
T |
3: 64,411,825 (GRCm39) |
C248S |
probably damaging |
Het |
| Vmn2r87 |
A |
T |
10: 130,314,940 (GRCm39) |
D215E |
probably damaging |
Het |
| Xkr4 |
T |
G |
1: 3,740,911 (GRCm39) |
I221L |
probably benign |
Het |
| Zfp366 |
T |
C |
13: 99,382,895 (GRCm39) |
I686T |
probably benign |
Het |
| Zfp398 |
T |
A |
6: 47,843,666 (GRCm39) |
C573S |
probably damaging |
Het |
|
| Other mutations in Abca16 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00417:Abca16
|
APN |
7 |
120,022,982 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL00590:Abca16
|
APN |
7 |
120,023,038 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01320:Abca16
|
APN |
7 |
120,038,422 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01322:Abca16
|
APN |
7 |
120,038,422 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01613:Abca16
|
APN |
7 |
120,140,500 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL01774:Abca16
|
APN |
7 |
120,021,024 (GRCm39) |
splice site |
probably benign |
|
|
IGL01774:Abca16
|
APN |
7 |
120,077,058 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01797:Abca16
|
APN |
7 |
120,113,760 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL02406:Abca16
|
APN |
7 |
120,139,825 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02437:Abca16
|
APN |
7 |
120,132,952 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02541:Abca16
|
APN |
7 |
120,113,881 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL02576:Abca16
|
APN |
7 |
120,032,678 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02578:Abca16
|
APN |
7 |
120,023,179 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03156:Abca16
|
APN |
7 |
120,023,074 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
IGL03381:Abca16
|
APN |
7 |
120,127,041 (GRCm39) |
missense |
probably benign |
0.12 |
|
PIT4802001:Abca16
|
UTSW |
7 |
120,139,351 (GRCm39) |
missense |
probably benign |
0.31 |
|
R0024:Abca16
|
UTSW |
7 |
120,032,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0026:Abca16
|
UTSW |
7 |
120,077,146 (GRCm39) |
splice site |
probably benign |
|
|
R0026:Abca16
|
UTSW |
7 |
120,077,146 (GRCm39) |
splice site |
probably benign |
|
|
R0123:Abca16
|
UTSW |
7 |
120,139,378 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0134:Abca16
|
UTSW |
7 |
120,139,378 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0225:Abca16
|
UTSW |
7 |
120,139,378 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0346:Abca16
|
UTSW |
7 |
120,035,155 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0355:Abca16
|
UTSW |
7 |
120,023,021 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R0358:Abca16
|
UTSW |
7 |
120,143,939 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0525:Abca16
|
UTSW |
7 |
120,065,033 (GRCm39) |
nonsense |
probably null |
|
|
R0617:Abca16
|
UTSW |
7 |
120,032,834 (GRCm39) |
splice site |
probably benign |
|
|
R0625:Abca16
|
UTSW |
7 |
120,035,116 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0835:Abca16
|
UTSW |
7 |
120,065,007 (GRCm39) |
missense |
probably benign |
0.42 |
|
R1445:Abca16
|
UTSW |
7 |
120,119,256 (GRCm39) |
missense |
probably benign |
0.41 |
|
R1535:Abca16
|
UTSW |
7 |
120,139,928 (GRCm39) |
missense |
probably benign |
0.30 |
|
R1567:Abca16
|
UTSW |
7 |
120,030,352 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1694:Abca16
|
UTSW |
7 |
120,119,307 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1860:Abca16
|
UTSW |
7 |
120,133,986 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1876:Abca16
|
UTSW |
7 |
120,032,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1913:Abca16
|
UTSW |
7 |
120,140,463 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1940:Abca16
|
UTSW |
7 |
120,032,832 (GRCm39) |
splice site |
probably benign |
|
|
R2042:Abca16
|
UTSW |
7 |
120,143,941 (GRCm39) |
missense |
probably benign |
|
|
R2115:Abca16
|
UTSW |
7 |
120,139,868 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2122:Abca16
|
UTSW |
7 |
120,119,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2265:Abca16
|
UTSW |
7 |
120,030,383 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2267:Abca16
|
UTSW |
7 |
120,030,383 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2269:Abca16
|
UTSW |
7 |
120,030,383 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2993:Abca16
|
UTSW |
7 |
120,134,384 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3055:Abca16
|
UTSW |
7 |
120,035,074 (GRCm39) |
missense |
probably benign |
0.05 |
|
R3956:Abca16
|
UTSW |
7 |
120,126,975 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4114:Abca16
|
UTSW |
7 |
120,126,290 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4441:Abca16
|
UTSW |
7 |
120,127,024 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4601:Abca16
|
UTSW |
7 |
120,035,920 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4706:Abca16
|
UTSW |
7 |
120,064,988 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4807:Abca16
|
UTSW |
7 |
120,139,832 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4824:Abca16
|
UTSW |
7 |
120,074,702 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R4937:Abca16
|
UTSW |
7 |
120,126,309 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5152:Abca16
|
UTSW |
7 |
120,139,846 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5257:Abca16
|
UTSW |
7 |
120,035,992 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5258:Abca16
|
UTSW |
7 |
120,035,992 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5330:Abca16
|
UTSW |
7 |
120,102,600 (GRCm39) |
missense |
probably benign |
0.15 |
|
R5388:Abca16
|
UTSW |
7 |
120,139,969 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5590:Abca16
|
UTSW |
7 |
120,143,995 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5810:Abca16
|
UTSW |
7 |
120,035,155 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6030:Abca16
|
UTSW |
7 |
120,133,021 (GRCm39) |
missense |
probably benign |
|
|
R6030:Abca16
|
UTSW |
7 |
120,133,021 (GRCm39) |
missense |
probably benign |
|
|
R6161:Abca16
|
UTSW |
7 |
120,139,934 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6313:Abca16
|
UTSW |
7 |
120,126,344 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6485:Abca16
|
UTSW |
7 |
120,026,390 (GRCm39) |
nonsense |
probably null |
|
|
R6527:Abca16
|
UTSW |
7 |
120,076,995 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6772:Abca16
|
UTSW |
7 |
120,126,276 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6885:Abca16
|
UTSW |
7 |
120,119,332 (GRCm39) |
missense |
probably benign |
0.07 |
|
R6899:Abca16
|
UTSW |
7 |
120,126,264 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6941:Abca16
|
UTSW |
7 |
120,140,370 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6990:Abca16
|
UTSW |
7 |
120,126,950 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7059:Abca16
|
UTSW |
7 |
120,020,971 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7144:Abca16
|
UTSW |
7 |
120,032,796 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7146:Abca16
|
UTSW |
7 |
120,126,974 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7193:Abca16
|
UTSW |
7 |
120,026,409 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7308:Abca16
|
UTSW |
7 |
120,022,993 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7449:Abca16
|
UTSW |
7 |
120,035,131 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7617:Abca16
|
UTSW |
7 |
120,102,694 (GRCm39) |
nonsense |
probably null |
|
|
R7646:Abca16
|
UTSW |
7 |
120,113,937 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7750:Abca16
|
UTSW |
7 |
120,113,928 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7763:Abca16
|
UTSW |
7 |
120,113,825 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7840:Abca16
|
UTSW |
7 |
120,074,689 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7946:Abca16
|
UTSW |
7 |
120,126,398 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8018:Abca16
|
UTSW |
7 |
120,132,866 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8170:Abca16
|
UTSW |
7 |
120,065,005 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8413:Abca16
|
UTSW |
7 |
120,023,123 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8461:Abca16
|
UTSW |
7 |
120,035,918 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8858:Abca16
|
UTSW |
7 |
120,052,327 (GRCm39) |
missense |
probably benign |
|
|
R8881:Abca16
|
UTSW |
7 |
120,074,794 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9272:Abca16
|
UTSW |
7 |
120,076,993 (GRCm39) |
missense |
probably benign |
0.13 |
|
R9303:Abca16
|
UTSW |
7 |
120,126,989 (GRCm39) |
missense |
probably benign |
0.25 |
|
R9305:Abca16
|
UTSW |
7 |
120,126,989 (GRCm39) |
missense |
probably benign |
0.25 |
|
R9320:Abca16
|
UTSW |
7 |
120,139,320 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9413:Abca16
|
UTSW |
7 |
120,126,422 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9512:Abca16
|
UTSW |
7 |
120,022,963 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9559:Abca16
|
UTSW |
7 |
120,021,019 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9615:Abca16
|
UTSW |
7 |
120,126,404 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9641:Abca16
|
UTSW |
7 |
120,126,308 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R9643:Abca16
|
UTSW |
7 |
120,065,023 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R9674:Abca16
|
UTSW |
7 |
120,074,668 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R9714:Abca16
|
UTSW |
7 |
120,030,383 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9799:Abca16
|
UTSW |
7 |
120,132,998 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9800:Abca16
|
UTSW |
7 |
120,119,283 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
RF020:Abca16
|
UTSW |
7 |
120,132,880 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
X0066:Abca16
|
UTSW |
7 |
120,102,609 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGCATGGCTGAAACAGGACC -3'
(R):5'- GTAATGGAAGCATCAGGGCC -3'
Sequencing Primer
(F):5'- ATTCCAGCACTTGGGGAATC -3'
(R):5'- CATCAGGGCCAGAAAGTGTC -3'
|
| Posted On |
2019-10-17 |
Incidental Mutation