|Institutional Source||Beutler Lab|
|Gene Name||solute carrier family 39 (zinc transporter), member 12|
|Is this an essential gene?||Probably non essential (E-score: 0.064)|
|Stock #||R7568 (G1)|
|Chromosomal Location||14388316-14494977 bp(+) (GRCm38)|
|Type of Mutation||splice site|
|DNA Base Change (assembly)||T to A at 14400128 bp (GRCm38)|
|Amino Acid Change|
|Ref Sequence||ENSEMBL: ENSMUSP00000110379 (fasta)|
|Gene Model||predicted gene model for transcript(s): [ENSMUST00000082290] [ENSMUST00000114731]|
|Coding Region Coverage||
|MGI Phenotype||FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A12 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Aug 2008]|
|Allele List at MGI|
|Other mutations in this stock||
|Other mutations in Slc39a12||
(F):5'- GATGCAAGCTATGAGTGGGC -3'
(R):5'- CTGTAAAATCATCTGGAGAAGGC -3'
(F):5'- AGTGGGCATGCACTTCAG -3'
(R):5'- GAGAAGGCAAGGCTTTTCTTCCC -3'