Incidental Mutation 'R7570:Patj'
| ID |
586024 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Patj
|
| Ensembl Gene |
ENSMUSG00000061859 |
| Gene Name |
PATJ, crumbs cell polarity complex component |
| Synonyms |
Inadl, Cipp |
| MMRRC Submission |
045631-MU
|
| Accession Numbers |
Genbank: NM_172696; MGI: 1277960 |
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7570 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
4 |
| Chromosomal Location |
98395785-98719603 bp(+) (GRCm38) |
| Type of Mutation |
splice site (6 bp from exon) |
| DNA Base Change (assembly) |
T to A
at 98424500 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000102649
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000041284]
[ENSMUST00000107030]
[ENSMUST00000107033]
[ENSMUST00000107034]
|
| AlphaFold |
Q63ZW7 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000041284
|
| SMART Domains |
Protein: ENSMUSP00000049176
Gene: ENSMUSG00000061859
| Domain | Start | End | E-Value | Type |
|---|
|
L27
|
8 |
68 |
6.53e-9 |
SMART |
|
PDZ
|
143 |
221 |
1.78e-20 |
SMART |
|
PDZ
|
256 |
328 |
1.15e-23 |
SMART |
|
PDZ
|
374 |
453 |
3.15e-21 |
SMART |
|
coiled coil region
|
486 |
513 |
N/A |
INTRINSIC |
|
PDZ
|
570 |
641 |
1.28e-12 |
SMART |
|
PDZ
|
696 |
775 |
9.5e-16 |
SMART |
|
low complexity region
|
980 |
991 |
N/A |
INTRINSIC |
|
low complexity region
|
1054 |
1062 |
N/A |
INTRINSIC |
|
PDZ
|
1083 |
1166 |
8.65e-19 |
SMART |
|
PDZ
|
1253 |
1328 |
6.12e-19 |
SMART |
|
low complexity region
|
1356 |
1366 |
N/A |
INTRINSIC |
|
low complexity region
|
1410 |
1428 |
N/A |
INTRINSIC |
|
PDZ
|
1480 |
1555 |
4.36e-24 |
SMART |
|
PDZ
|
1577 |
1650 |
2.49e-19 |
SMART |
|
PDZ
|
1718 |
1795 |
2.13e-18 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000107030
|
| SMART Domains |
Protein: ENSMUSP00000102645
Gene: ENSMUSG00000061859
| Domain | Start | End | E-Value | Type |
|---|
|
L27
|
8 |
68 |
6.53e-9 |
SMART |
|
PDZ
|
143 |
221 |
1.78e-20 |
SMART |
|
PDZ
|
256 |
328 |
1.15e-23 |
SMART |
|
PDZ
|
374 |
453 |
3.15e-21 |
SMART |
|
coiled coil region
|
486 |
513 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000107033
|
| SMART Domains |
Protein: ENSMUSP00000102648
Gene: ENSMUSG00000061859
| Domain | Start | End | E-Value | Type |
|---|
|
L27
|
8 |
68 |
6.53e-9 |
SMART |
|
PDZ
|
143 |
221 |
1.78e-20 |
SMART |
|
PDZ
|
256 |
328 |
1.15e-23 |
SMART |
|
PDZ
|
374 |
453 |
3.15e-21 |
SMART |
|
coiled coil region
|
486 |
513 |
N/A |
INTRINSIC |
|
low complexity region
|
648 |
659 |
N/A |
INTRINSIC |
|
low complexity region
|
722 |
730 |
N/A |
INTRINSIC |
|
PDZ
|
751 |
834 |
8.65e-19 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000107034
|
| SMART Domains |
Protein: ENSMUSP00000102649
Gene: ENSMUSG00000061859
| Domain | Start | End | E-Value | Type |
|---|
|
L27
|
8 |
68 |
6.53e-9 |
SMART |
|
PDZ
|
143 |
221 |
1.78e-20 |
SMART |
|
PDZ
|
256 |
328 |
1.15e-23 |
SMART |
|
PDZ
|
374 |
453 |
3.15e-21 |
SMART |
|
coiled coil region
|
486 |
513 |
N/A |
INTRINSIC |
|
PDZ
|
566 |
637 |
1.28e-12 |
SMART |
|
PDZ
|
692 |
771 |
9.5e-16 |
SMART |
|
low complexity region
|
976 |
987 |
N/A |
INTRINSIC |
|
low complexity region
|
1050 |
1058 |
N/A |
INTRINSIC |
|
PDZ
|
1079 |
1162 |
8.65e-19 |
SMART |
|
PDZ
|
1249 |
1324 |
6.12e-19 |
SMART |
|
low complexity region
|
1352 |
1362 |
N/A |
INTRINSIC |
|
low complexity region
|
1382 |
1400 |
N/A |
INTRINSIC |
|
PDZ
|
1452 |
1499 |
7.78e0 |
SMART |
|
| Meta Mutation Damage Score |
0.9756 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
98% (104/106) |
| MGI Phenotype |
FUNCTION: This gene encodes a multivalent PDZ domain protein, which is expressed exclusively in brain and kidney. This protein selectively interacts with inward rectifier K+ (Kir) family members, N-methyl-D-aspartate receptor subunits, neurexins and neuroligins, as well as cell surface molecules enriched in synaptic membranes. Thus, this protein may serve as a scaffold that brings structurally diverse but functionally connected proteins into close proximity at the synapse. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
All alleles(5) : Gene trapped(5) |
| Other mutations in this stock |
Total: 106 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930590J08Rik |
C |
T |
6: 91,934,610 (GRCm38) |
T613I |
probably benign |
Het |
| 9130019O22Rik |
T |
A |
7: 127,385,283 (GRCm38) |
S216C |
probably benign |
Het |
| Ajuba |
T |
C |
14: 54,576,402 (GRCm38) |
E288G |
probably damaging |
Het |
| Ankrd12 |
C |
T |
17: 65,985,360 (GRCm38) |
R1026K |
probably benign |
Het |
| Apol7b |
T |
C |
15: 77,423,474 (GRCm38) |
T274A |
probably benign |
Het |
| Arid4a |
A |
T |
12: 71,063,142 (GRCm38) |
R86* |
probably null |
Het |
| Asnsd1 |
C |
T |
1: 53,348,258 (GRCm38) |
G70D |
probably damaging |
Het |
| Atg4c |
T |
A |
4: 99,228,560 (GRCm38) |
V313D |
possibly damaging |
Het |
| Atp13a5 |
A |
C |
16: 29,266,963 (GRCm38) |
C885G |
probably damaging |
Het |
| Bpifb9a |
A |
T |
2: 154,262,263 (GRCm38) |
I209F |
possibly damaging |
Het |
| Bsn |
T |
C |
9: 108,113,543 (GRCm38) |
D1670G |
probably damaging |
Het |
| Cct8 |
T |
A |
16: 87,491,322 (GRCm38) |
I121F |
probably benign |
Het |
| Cd209a |
T |
G |
8: 3,744,151 (GRCm38) |
D217A |
probably damaging |
Het |
| Cdk19 |
C |
T |
10: 40,477,958 (GRCm38) |
S456L |
possibly damaging |
Het |
| Chd9 |
C |
T |
8: 90,994,580 (GRCm38) |
H999Y |
unknown |
Het |
| Col5a1 |
G |
A |
2: 27,951,383 (GRCm38) |
V339M |
unknown |
Het |
| Cr2 |
G |
A |
1: 195,169,340 (GRCm38) |
R115* |
probably null |
Het |
| Cyb561 |
A |
T |
11: 105,937,644 (GRCm38) |
F62I |
probably damaging |
Het |
| Cyp2c38 |
A |
T |
19: 39,404,743 (GRCm38) |
N293K |
possibly damaging |
Het |
| Cyp2c69 |
A |
T |
19: 39,859,898 (GRCm38) |
D293E |
probably damaging |
Het |
| Dcbld2 |
T |
A |
16: 58,424,569 (GRCm38) |
C69S |
possibly damaging |
Het |
| Dcdc2a |
T |
C |
13: 25,119,373 (GRCm38) |
S296P |
probably benign |
Het |
| Dmxl1 |
T |
A |
18: 49,893,957 (GRCm38) |
I2044K |
possibly damaging |
Het |
| Dnah5 |
A |
G |
15: 28,346,952 (GRCm38) |
D2527G |
probably damaging |
Het |
| Dnah6 |
T |
C |
6: 73,149,430 (GRCm38) |
T1305A |
probably benign |
Het |
| Dnajc9 |
A |
G |
14: 20,388,644 (GRCm38) |
V47A |
probably benign |
Het |
| Dnmt3b |
A |
G |
2: 153,676,699 (GRCm38) |
Y594C |
probably damaging |
Het |
| Dph7 |
A |
G |
2: 24,965,630 (GRCm38) |
D147G |
probably damaging |
Het |
| Drap1 |
T |
C |
19: 5,423,352 (GRCm38) |
H164R |
possibly damaging |
Het |
| Dsg3 |
T |
A |
18: 20,527,780 (GRCm38) |
V392E |
possibly damaging |
Het |
| Dxo |
A |
G |
17: 34,837,640 (GRCm38) |
D81G |
probably benign |
Het |
| E230025N22Rik |
G |
T |
18: 36,695,592 (GRCm38) |
T11K |
probably benign |
Het |
| Esyt1 |
A |
G |
10: 128,518,932 (GRCm38) |
V533A |
possibly damaging |
Het |
| Etv3 |
T |
A |
3: 87,536,031 (GRCm38) |
C307* |
probably null |
Het |
| Fam114a1 |
T |
A |
5: 65,030,059 (GRCm38) |
|
probably null |
Het |
| Fam208b |
A |
G |
13: 3,573,621 (GRCm38) |
Y2110H |
probably damaging |
Het |
| Fam3c |
T |
A |
6: 22,326,405 (GRCm38) |
|
probably benign |
Het |
| Fbn1 |
G |
T |
2: 125,397,852 (GRCm38) |
T305K |
probably benign |
Het |
| Ggt1 |
A |
T |
10: 75,585,594 (GRCm38) |
I484F |
probably damaging |
Het |
| Gm10639 |
A |
T |
9: 78,304,469 (GRCm38) |
D171V |
possibly damaging |
Het |
| Gpatch1 |
T |
C |
7: 35,293,812 (GRCm38) |
D536G |
probably damaging |
Het |
| Gpx4 |
T |
C |
10: 80,055,041 (GRCm38) |
I189T |
probably damaging |
Het |
| Gsr |
T |
A |
8: 33,669,165 (GRCm38) |
C85S |
probably damaging |
Het |
| Havcr1 |
T |
A |
11: 46,770,542 (GRCm38) |
|
probably null |
Het |
| Heatr4 |
T |
C |
12: 83,979,644 (GRCm38) |
T280A |
probably benign |
Het |
| Hmcn2 |
A |
T |
2: 31,423,911 (GRCm38) |
E3532D |
probably benign |
Het |
| Hnrnpc |
T |
C |
14: 52,075,099 (GRCm38) |
N308S |
possibly damaging |
Het |
| Ighv8-9 |
A |
G |
12: 115,468,738 (GRCm38) |
V13A |
probably benign |
Het |
| Itgb2l |
A |
T |
16: 96,426,239 (GRCm38) |
F535I |
probably benign |
Het |
| Kdm5a |
T |
G |
6: 120,427,842 (GRCm38) |
D1348E |
probably damaging |
Het |
| Kndc1 |
CT |
C |
7: 139,923,775 (GRCm38) |
|
probably null |
Het |
| Ky |
A |
G |
9: 102,542,329 (GRCm38) |
I512V |
probably benign |
Het |
| Lamc1 |
A |
T |
1: 153,243,275 (GRCm38) |
F866Y |
possibly damaging |
Het |
| Lbx1 |
C |
A |
19: 45,235,248 (GRCm38) |
|
probably benign |
Het |
| Magel2 |
A |
G |
7: 62,378,910 (GRCm38) |
T521A |
possibly damaging |
Het |
| Mgam |
A |
T |
6: 40,746,433 (GRCm38) |
I491L |
probably benign |
Het |
| Mitd1 |
T |
C |
1: 37,890,192 (GRCm38) |
E40G |
probably damaging |
Het |
| Mpzl3 |
A |
G |
9: 45,070,687 (GRCm38) |
T218A |
probably benign |
Het |
| Mrpl42 |
A |
G |
10: 95,480,965 (GRCm38) |
S77P |
probably benign |
Het |
| Mup5 |
C |
T |
4: 61,834,674 (GRCm38) |
W37* |
probably null |
Het |
| Myh14 |
T |
C |
7: 44,632,426 (GRCm38) |
I803V |
probably benign |
Het |
| Ncor2 |
T |
A |
5: 125,030,089 (GRCm38) |
T744S |
|
Het |
| Ndufv3 |
A |
G |
17: 31,527,622 (GRCm38) |
D162G |
probably damaging |
Het |
| Nostrin |
A |
G |
2: 69,175,806 (GRCm38) |
E278G |
probably damaging |
Het |
| Nrxn1 |
T |
G |
17: 90,162,379 (GRCm38) |
E1288A |
probably benign |
Het |
| Olfr1205 |
A |
G |
2: 88,831,128 (GRCm38) |
N4D |
possibly damaging |
Het |
| Olfr623 |
C |
A |
7: 103,660,881 (GRCm38) |
R123L |
probably damaging |
Het |
| Olfr648 |
T |
A |
7: 104,179,748 (GRCm38) |
Y220F |
probably damaging |
Het |
| Olfr972 |
A |
T |
9: 39,873,455 (GRCm38) |
Y60F |
possibly damaging |
Het |
| Pcm1 |
T |
G |
8: 41,267,344 (GRCm38) |
I314R |
possibly damaging |
Het |
| Pcsk6 |
A |
G |
7: 66,033,898 (GRCm38) |
T754A |
probably benign |
Het |
| Pde2a |
A |
T |
7: 101,502,834 (GRCm38) |
N326I |
probably benign |
Het |
| Plekhg4 |
T |
C |
8: 105,378,684 (GRCm38) |
S594P |
possibly damaging |
Het |
| Plekhm3 |
T |
C |
1: 64,937,906 (GRCm38) |
D135G |
probably damaging |
Het |
| Plin4 |
A |
T |
17: 56,106,776 (GRCm38) |
M283K |
probably benign |
Het |
| Ppfia3 |
T |
C |
7: 45,340,748 (GRCm38) |
|
probably null |
Het |
| Prdm9 |
T |
C |
17: 15,555,652 (GRCm38) |
N179S |
probably benign |
Het |
| Prrt3 |
T |
C |
6: 113,494,488 (GRCm38) |
S908G |
probably damaging |
Het |
| Psg22 |
C |
A |
7: 18,722,735 (GRCm38) |
S181Y |
possibly damaging |
Het |
| Rcor3 |
C |
A |
1: 192,137,876 (GRCm38) |
G8V |
probably damaging |
Het |
| Rp1l1 |
T |
A |
14: 64,031,574 (GRCm38) |
C1536* |
probably null |
Het |
| Rpp25l |
T |
C |
4: 41,712,529 (GRCm38) |
H82R |
probably damaging |
Het |
| Rps3a1 |
T |
A |
3: 86,139,089 (GRCm38) |
M172L |
probably benign |
Het |
| Rtbdn |
T |
C |
8: 84,952,927 (GRCm38) |
L110P |
probably damaging |
Het |
| Ryr1 |
T |
A |
7: 29,078,585 (GRCm38) |
Q2169L |
probably damaging |
Het |
| Scn4a |
A |
T |
11: 106,320,473 (GRCm38) |
C1573S |
possibly damaging |
Het |
| Sec16b |
A |
T |
1: 157,531,395 (GRCm38) |
|
probably null |
Het |
| Serpina1a |
A |
T |
12: 103,853,837 (GRCm38) |
D383E |
possibly damaging |
Het |
| Sh3gl3 |
T |
C |
7: 82,285,077 (GRCm38) |
M262T |
probably benign |
Het |
| Sos2 |
G |
A |
12: 69,590,880 (GRCm38) |
T1052M |
probably damaging |
Het |
| Spag16 |
G |
A |
1: 69,996,841 (GRCm38) |
V343I |
probably benign |
Het |
| Spocd1 |
T |
G |
4: 129,930,164 (GRCm38) |
D251E |
|
Het |
| Stc2 |
G |
T |
11: 31,367,798 (GRCm38) |
N74K |
probably damaging |
Het |
| Thbs3 |
C |
T |
3: 89,219,052 (GRCm38) |
Q227* |
probably null |
Het |
| Tmem92 |
A |
C |
11: 94,778,990 (GRCm38) |
I105R |
probably benign |
Het |
| Tmod1 |
T |
A |
4: 46,083,632 (GRCm38) |
N20K |
probably benign |
Het |
| Tns1 |
T |
C |
1: 73,953,479 (GRCm38) |
D53G |
probably damaging |
Het |
| Tspan33 |
T |
A |
6: 29,717,338 (GRCm38) |
L246Q |
probably damaging |
Het |
| Ttc16 |
A |
G |
2: 32,768,968 (GRCm38) |
L392P |
probably damaging |
Het |
| Uggt1 |
T |
A |
1: 36,185,838 (GRCm38) |
T572S |
probably benign |
Het |
| Usp17la |
A |
T |
7: 104,860,397 (GRCm38) |
T70S |
probably damaging |
Het |
| Usp31 |
C |
T |
7: 121,674,963 (GRCm38) |
R370H |
probably damaging |
Het |
| Wdr83 |
C |
T |
8: 85,079,834 (GRCm38) |
V112M |
probably damaging |
Het |
| Zbtb25 |
T |
A |
12: 76,369,592 (GRCm38) |
|
probably benign |
Het |
| Zfp110 |
T |
A |
7: 12,849,340 (GRCm38) |
N638K |
possibly damaging |
Het |
| Zfp820 |
T |
C |
17: 21,819,013 (GRCm38) |
T445A |
probably benign |
Het |
|
| Other mutations in Patj |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00089:Patj
|
APN |
4 |
98,465,106 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00095:Patj
|
APN |
4 |
98,535,562 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
IGL00517:Patj
|
APN |
4 |
98,441,071 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
IGL00802:Patj
|
APN |
4 |
98,424,406 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
IGL01064:Patj
|
APN |
4 |
98,496,973 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
IGL01110:Patj
|
APN |
4 |
98,413,024 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01407:Patj
|
APN |
4 |
98,413,050 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
IGL01821:Patj
|
APN |
4 |
98,456,211 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02399:Patj
|
APN |
4 |
98,591,936 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02494:Patj
|
APN |
4 |
98,703,987 (GRCm38) |
splice site |
probably benign |
|
|
IGL02803:Patj
|
APN |
4 |
98,426,064 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02931:Patj
|
APN |
4 |
98,411,173 (GRCm38) |
splice site |
probably benign |
|
|
IGL03017:Patj
|
APN |
4 |
98,465,027 (GRCm38) |
splice site |
probably benign |
|
|
IGL03115:Patj
|
APN |
4 |
98,443,803 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03209:Patj
|
APN |
4 |
98,465,140 (GRCm38) |
missense |
probably null |
1.00 |
|
IGL03377:Patj
|
APN |
4 |
98,465,104 (GRCm38) |
missense |
probably damaging |
1.00 |
|
D4186:Patj
|
UTSW |
4 |
98,638,762 (GRCm38) |
missense |
probably benign |
0.17 |
|
PIT4531001:Patj
|
UTSW |
4 |
98,441,090 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R0136:Patj
|
UTSW |
4 |
98,667,648 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0294:Patj
|
UTSW |
4 |
98,497,048 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0376:Patj
|
UTSW |
4 |
98,568,987 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0463:Patj
|
UTSW |
4 |
98,674,308 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0465:Patj
|
UTSW |
4 |
98,535,507 (GRCm38) |
splice site |
probably null |
|
|
R0466:Patj
|
UTSW |
4 |
98,688,156 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0544:Patj
|
UTSW |
4 |
98,569,110 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0624:Patj
|
UTSW |
4 |
98,681,235 (GRCm38) |
splice site |
probably benign |
|
|
R0657:Patj
|
UTSW |
4 |
98,667,648 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1281:Patj
|
UTSW |
4 |
98,416,695 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1393:Patj
|
UTSW |
4 |
98,424,411 (GRCm38) |
missense |
probably benign |
0.01 |
|
R1480:Patj
|
UTSW |
4 |
98,469,582 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1667:Patj
|
UTSW |
4 |
98,413,027 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1728:Patj
|
UTSW |
4 |
98,431,780 (GRCm38) |
missense |
possibly damaging |
0.50 |
|
R1729:Patj
|
UTSW |
4 |
98,431,780 (GRCm38) |
missense |
possibly damaging |
0.50 |
|
R1797:Patj
|
UTSW |
4 |
98,687,438 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1818:Patj
|
UTSW |
4 |
98,623,648 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R1835:Patj
|
UTSW |
4 |
98,491,590 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1880:Patj
|
UTSW |
4 |
98,497,240 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2009:Patj
|
UTSW |
4 |
98,456,169 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2090:Patj
|
UTSW |
4 |
98,437,323 (GRCm38) |
unclassified |
probably benign |
|
|
R2120:Patj
|
UTSW |
4 |
98,456,225 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2180:Patj
|
UTSW |
4 |
98,523,502 (GRCm38) |
critical splice donor site |
probably null |
|
|
R2655:Patj
|
UTSW |
4 |
98,437,450 (GRCm38) |
missense |
possibly damaging |
0.64 |
|
R3156:Patj
|
UTSW |
4 |
98,674,228 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3749:Patj
|
UTSW |
4 |
98,469,600 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3767:Patj
|
UTSW |
4 |
98,681,219 (GRCm38) |
nonsense |
probably null |
|
|
R3913:Patj
|
UTSW |
4 |
98,569,101 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R3917:Patj
|
UTSW |
4 |
98,592,008 (GRCm38) |
nonsense |
probably null |
|
|
R3918:Patj
|
UTSW |
4 |
98,456,218 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4299:Patj
|
UTSW |
4 |
98,677,321 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R4355:Patj
|
UTSW |
4 |
98,650,454 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
R4471:Patj
|
UTSW |
4 |
98,535,579 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4762:Patj
|
UTSW |
4 |
98,405,570 (GRCm38) |
nonsense |
probably null |
|
|
R4877:Patj
|
UTSW |
4 |
98,569,058 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R4945:Patj
|
UTSW |
4 |
98,495,064 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R5274:Patj
|
UTSW |
4 |
98,518,981 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5343:Patj
|
UTSW |
4 |
98,676,193 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5554:Patj
|
UTSW |
4 |
98,454,396 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R5688:Patj
|
UTSW |
4 |
98,520,810 (GRCm38) |
nonsense |
probably null |
|
|
R5880:Patj
|
UTSW |
4 |
98,411,145 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R5972:Patj
|
UTSW |
4 |
98,569,053 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R6149:Patj
|
UTSW |
4 |
98,424,325 (GRCm38) |
missense |
possibly damaging |
0.72 |
|
R6192:Patj
|
UTSW |
4 |
98,456,157 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6265:Patj
|
UTSW |
4 |
98,469,567 (GRCm38) |
missense |
probably benign |
0.08 |
|
R6350:Patj
|
UTSW |
4 |
98,405,618 (GRCm38) |
missense |
probably benign |
0.26 |
|
R6363:Patj
|
UTSW |
4 |
98,431,860 (GRCm38) |
missense |
probably benign |
0.25 |
|
R6434:Patj
|
UTSW |
4 |
98,491,629 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6496:Patj
|
UTSW |
4 |
98,416,752 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6896:Patj
|
UTSW |
4 |
98,426,050 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
R7039:Patj
|
UTSW |
4 |
98,569,078 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R7040:Patj
|
UTSW |
4 |
98,441,080 (GRCm38) |
missense |
probably benign |
0.02 |
|
R7052:Patj
|
UTSW |
4 |
98,677,260 (GRCm38) |
missense |
probably benign |
0.03 |
|
R7066:Patj
|
UTSW |
4 |
98,413,197 (GRCm38) |
missense |
probably benign |
0.24 |
|
R7236:Patj
|
UTSW |
4 |
98,411,057 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7242:Patj
|
UTSW |
4 |
98,591,933 (GRCm38) |
missense |
probably benign |
0.26 |
|
R7260:Patj
|
UTSW |
4 |
98,416,733 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R7412:Patj
|
UTSW |
4 |
98,411,139 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R7493:Patj
|
UTSW |
4 |
98,495,061 (GRCm38) |
missense |
probably benign |
0.41 |
|
R7571:Patj
|
UTSW |
4 |
98,568,980 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7626:Patj
|
UTSW |
4 |
98,546,987 (GRCm38) |
missense |
probably benign |
0.35 |
|
R7658:Patj
|
UTSW |
4 |
98,688,179 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7664:Patj
|
UTSW |
4 |
98,496,950 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R7669:Patj
|
UTSW |
4 |
98,518,942 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7796:Patj
|
UTSW |
4 |
98,546,983 (GRCm38) |
start codon destroyed |
probably benign |
0.05 |
|
R7870:Patj
|
UTSW |
4 |
98,424,316 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7883:Patj
|
UTSW |
4 |
98,611,135 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7948:Patj
|
UTSW |
4 |
98,424,310 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8050:Patj
|
UTSW |
4 |
98,538,964 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8183:Patj
|
UTSW |
4 |
98,674,229 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R8239:Patj
|
UTSW |
4 |
98,682,071 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R8483:Patj
|
UTSW |
4 |
98,424,302 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8546:Patj
|
UTSW |
4 |
98,437,397 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8746:Patj
|
UTSW |
4 |
98,505,830 (GRCm38) |
intron |
probably benign |
|
|
R8844:Patj
|
UTSW |
4 |
98,591,969 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8905:Patj
|
UTSW |
4 |
98,497,175 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8912:Patj
|
UTSW |
4 |
98,497,328 (GRCm38) |
missense |
|
|
|
R8959:Patj
|
UTSW |
4 |
98,591,975 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9083:Patj
|
UTSW |
4 |
98,513,634 (GRCm38) |
missense |
probably benign |
0.03 |
|
R9173:Patj
|
UTSW |
4 |
98,638,721 (GRCm38) |
missense |
probably benign |
|
|
R9206:Patj
|
UTSW |
4 |
98,539,073 (GRCm38) |
missense |
unknown |
|
|
R9208:Patj
|
UTSW |
4 |
98,539,073 (GRCm38) |
missense |
unknown |
|
|
R9347:Patj
|
UTSW |
4 |
98,688,247 (GRCm38) |
missense |
probably benign |
0.19 |
|
R9560:Patj
|
UTSW |
4 |
98,682,052 (GRCm38) |
missense |
probably benign |
0.29 |
|
R9609:Patj
|
UTSW |
4 |
98,688,236 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9617:Patj
|
UTSW |
4 |
98,505,754 (GRCm38) |
missense |
probably benign |
0.03 |
|
R9658:Patj
|
UTSW |
4 |
98,465,140 (GRCm38) |
missense |
probably null |
1.00 |
|
R9756:Patj
|
UTSW |
4 |
98,677,298 (GRCm38) |
missense |
probably benign |
|
|
Z1176:Patj
|
UTSW |
4 |
98,676,318 (GRCm38) |
nonsense |
probably null |
|
|
Z1176:Patj
|
UTSW |
4 |
98,611,130 (GRCm38) |
missense |
probably benign |
0.11 |
|
Z1177:Patj
|
UTSW |
4 |
98,497,174 (GRCm38) |
missense |
probably benign |
0.01 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGTTCAAGGGATGACCAGTG -3'
(R):5'- CCTGCTTTTATTCATGGGGAAG -3'
Sequencing Primer
(F):5'- TGACCAGTGAACAAGTTGCTC -3'
(R):5'- TCTTGTCAAAAAGGCAGGCTCTC -3'
|
| Posted On |
2019-10-18 |
Incidental Mutation