Incidental Mutation 'R7575:Usp40'
| ID |
586298 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Usp40
|
| Ensembl Gene |
ENSMUSG00000005501 |
| Gene Name |
ubiquitin specific peptidase 40 |
| Synonyms |
B230215L03Rik |
| MMRRC Submission |
045632-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7575 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
87872841-87936273 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to C
at 87877682 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Tryptophan
at position 1158
(L1158W)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000140107
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000040783]
[ENSMUST00000187758]
[ENSMUST00000188332]
[ENSMUST00000189448]
[ENSMUST00000190061]
|
| AlphaFold |
Q8BWR4 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000040783
AA Change: L1069W
PolyPhen 2
Score 0.993 (Sensitivity: 0.70; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000038533
Gene: ENSMUSG00000005501
AA Change: L1069W
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:UCH
|
40 |
344 |
1.1e-31 |
PFAM |
|
Pfam:UCH_1
|
41 |
320 |
1.2e-20 |
PFAM |
|
low complexity region
|
641 |
650 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000187758
AA Change: L1158W
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000140107
Gene: ENSMUSG00000005501
AA Change: L1158W
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:UCH
|
40 |
346 |
8.7e-41 |
PFAM |
|
Pfam:UCH_1
|
41 |
319 |
2.4e-22 |
PFAM |
|
low complexity region
|
641 |
650 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000188332
|
| SMART Domains |
Protein: ENSMUSP00000140574
Gene: ENSMUSG00000005501
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:UCH
|
40 |
70 |
5.9e-6 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000189409
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000189448
|
| SMART Domains |
Protein: ENSMUSP00000139626
Gene: ENSMUSG00000070738
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
82 |
93 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000190061
|
| SMART Domains |
Protein: ENSMUSP00000139658
Gene: ENSMUSG00000070738
| Domain | Start | End | E-Value | Type |
|---|
|
DAGKa
|
1 |
95 |
7.6e-26 |
SMART |
|
Blast:DAGKa
|
119 |
188 |
1e-23 |
BLAST |
|
low complexity region
|
301 |
312 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP40 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Mar 2008]
|
| Allele List at MGI |
All alleles(4) : Targeted, other(2) Gene trapped(2) |
| Other mutations in this stock |
Total: 91 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 3425401B19Rik |
C |
T |
14: 32,384,589 (GRCm39) |
V459I |
probably benign |
Het |
| 4921539E11Rik |
T |
C |
4: 103,088,192 (GRCm39) |
D439G |
probably damaging |
Het |
| Adam18 |
T |
C |
8: 25,115,873 (GRCm39) |
N607S |
possibly damaging |
Het |
| Adamtsl3 |
A |
T |
7: 82,223,756 (GRCm39) |
N1179I |
possibly damaging |
Het |
| Adarb1 |
A |
G |
10: 77,139,129 (GRCm39) |
F552S |
probably damaging |
Het |
| Ago1 |
T |
C |
4: 126,347,701 (GRCm39) |
E394G |
probably benign |
Het |
| Alb |
G |
A |
5: 90,613,788 (GRCm39) |
C224Y |
probably damaging |
Het |
| Alms1 |
T |
A |
6: 85,599,141 (GRCm39) |
H1322Q |
possibly damaging |
Het |
| Arhgef18 |
T |
G |
8: 3,501,635 (GRCm39) |
V643G |
probably damaging |
Het |
| Asah2 |
T |
C |
19: 31,994,103 (GRCm39) |
Q414R |
probably benign |
Het |
| Atpsckmt |
C |
T |
15: 31,606,186 (GRCm39) |
A48V |
probably damaging |
Het |
| Bbc3 |
G |
A |
7: 16,046,292 (GRCm39) |
R76H |
possibly damaging |
Het |
| Bub1b |
T |
A |
2: 118,471,639 (GRCm39) |
S1000T |
possibly damaging |
Het |
| Bud23 |
A |
T |
5: 135,089,982 (GRCm39) |
Y70* |
probably null |
Het |
| C1d |
A |
G |
11: 17,212,694 (GRCm39) |
E13G |
probably damaging |
Het |
| Camk1 |
T |
A |
6: 113,315,325 (GRCm39) |
I158F |
probably damaging |
Het |
| Ccr2 |
A |
C |
9: 123,905,843 (GRCm39) |
D41A |
probably benign |
Het |
| Cdh18 |
G |
T |
15: 23,400,683 (GRCm39) |
E348* |
probably null |
Het |
| Col6a3 |
A |
G |
1: 90,738,321 (GRCm39) |
L1066P |
possibly damaging |
Het |
| Cyp11b1 |
T |
A |
15: 74,711,162 (GRCm39) |
D172V |
probably benign |
Het |
| Cyp2j8 |
A |
G |
4: 96,358,785 (GRCm39) |
I378T |
possibly damaging |
Het |
| Cys1 |
T |
A |
12: 24,718,647 (GRCm39) |
K69* |
probably null |
Het |
| Dip2c |
A |
G |
13: 9,678,048 (GRCm39) |
K1165E |
probably damaging |
Het |
| Drd3 |
A |
T |
16: 43,637,496 (GRCm39) |
I232F |
probably benign |
Het |
| Dusp7 |
T |
C |
9: 106,250,876 (GRCm39) |
C334R |
probably damaging |
Het |
| Eppk1 |
A |
G |
15: 75,995,442 (GRCm39) |
S480P |
not run |
Het |
| Erc1 |
G |
T |
6: 119,801,721 (GRCm39) |
P99T |
possibly damaging |
Het |
| Fam170b |
C |
T |
14: 32,558,155 (GRCm39) |
P330L |
unknown |
Het |
| Fasn |
G |
T |
11: 120,703,513 (GRCm39) |
T1573K |
possibly damaging |
Het |
| Fras1 |
A |
T |
5: 96,691,173 (GRCm39) |
T130S |
probably benign |
Het |
| Fzd4 |
A |
G |
7: 89,056,918 (GRCm39) |
I322V |
possibly damaging |
Het |
| Gbp10 |
G |
A |
5: 105,384,015 (GRCm39) |
|
probably benign |
Het |
| Gdpd4 |
A |
T |
7: 97,647,448 (GRCm39) |
H365L |
probably benign |
Het |
| Gfy |
A |
G |
7: 44,827,524 (GRCm39) |
S191P |
probably benign |
Het |
| Ghr |
A |
T |
15: 3,349,994 (GRCm39) |
S395T |
probably damaging |
Het |
| Git2 |
C |
T |
5: 114,904,550 (GRCm39) |
R123H |
probably damaging |
Het |
| Htt |
A |
G |
5: 35,062,987 (GRCm39) |
D2873G |
probably damaging |
Het |
| Idua |
A |
T |
5: 108,829,565 (GRCm39) |
D476V |
probably damaging |
Het |
| Inppl1 |
G |
A |
7: 101,477,689 (GRCm39) |
R683W |
probably damaging |
Het |
| Ipp |
T |
C |
4: 116,389,841 (GRCm39) |
S466P |
probably benign |
Het |
| Iqgap2 |
A |
G |
13: 95,798,131 (GRCm39) |
V1058A |
probably damaging |
Het |
| Jmy |
A |
T |
13: 93,601,103 (GRCm39) |
Y434* |
probably null |
Het |
| Kmt2d |
CTGCTGCTG |
CTGCTGCTGATGCTGCTG |
15: 98,747,492 (GRCm39) |
|
probably benign |
Het |
| Mogs |
T |
G |
6: 83,092,816 (GRCm39) |
S85R |
probably damaging |
Het |
| Mroh2b |
A |
T |
15: 4,964,087 (GRCm39) |
D863V |
probably damaging |
Het |
| Mtmr10 |
A |
T |
7: 63,947,213 (GRCm39) |
I43F |
probably damaging |
Het |
| Mtr |
T |
C |
13: 12,213,963 (GRCm39) |
D903G |
probably benign |
Het |
| Ncor1 |
A |
G |
11: 62,274,082 (GRCm39) |
V186A |
probably benign |
Het |
| Notch3 |
C |
T |
17: 32,373,793 (GRCm39) |
D472N |
possibly damaging |
Het |
| Or4k44 |
A |
T |
2: 111,368,597 (GRCm39) |
F12L |
probably damaging |
Het |
| Or6c68 |
T |
C |
10: 129,157,728 (GRCm39) |
F79L |
probably damaging |
Het |
| Or8j3c |
A |
G |
2: 86,253,582 (GRCm39) |
F146S |
probably benign |
Het |
| Or9i1 |
T |
C |
19: 13,839,381 (GRCm39) |
S75P |
probably damaging |
Het |
| Oxr1 |
T |
G |
15: 41,686,758 (GRCm39) |
L547V |
possibly damaging |
Het |
| Pappa2 |
A |
T |
1: 158,642,100 (GRCm39) |
C1319S |
probably damaging |
Het |
| Papss1 |
A |
C |
3: 131,348,857 (GRCm39) |
K623N |
probably damaging |
Het |
| Parp4 |
T |
C |
14: 56,875,375 (GRCm39) |
F1198S |
probably benign |
Het |
| Pcare |
T |
A |
17: 72,057,850 (GRCm39) |
Q609L |
probably damaging |
Het |
| Pcnt |
A |
T |
10: 76,225,086 (GRCm39) |
V1806D |
probably benign |
Het |
| Pitx2 |
A |
T |
3: 129,009,375 (GRCm39) |
H98L |
probably damaging |
Het |
| Polq |
C |
A |
16: 36,911,496 (GRCm39) |
D2410E |
probably benign |
Het |
| Prdm9 |
C |
T |
17: 15,764,890 (GRCm39) |
C630Y |
probably damaging |
Het |
| Preb |
A |
T |
5: 31,115,839 (GRCm39) |
D201E |
probably damaging |
Het |
| Rasa3 |
A |
T |
8: 13,645,887 (GRCm39) |
I151N |
possibly damaging |
Het |
| Rasgrp2 |
T |
A |
19: 6,454,397 (GRCm39) |
S147T |
probably damaging |
Het |
| Rev3l |
A |
G |
10: 39,697,441 (GRCm39) |
D646G |
possibly damaging |
Het |
| Sdc1 |
A |
G |
12: 8,840,619 (GRCm39) |
E128G |
probably damaging |
Het |
| Slamf7 |
A |
C |
1: 171,466,762 (GRCm39) |
C148G |
probably damaging |
Het |
| Slc19a2 |
T |
C |
1: 164,084,691 (GRCm39) |
S194P |
probably damaging |
Het |
| Spata31 |
C |
T |
13: 65,070,726 (GRCm39) |
P958L |
unknown |
Het |
| Sprr2b |
CTGAGCCTTGTCCTCCTCCAAAGTGCCCTGAGCCTTGTCCTCCCCCAGTATGCTGTGAGCCTTGTCCTCCTCCAAAGTGCCCTGAGCCTTGTCCTCCCCCAGTATGCTGTGAGCCTTGTCCTCC |
CTGAGCCTTGTCCTCCTCCAAAGTGCCCTGAGCCTTGTCCTCCCCCAGTATGCTGTGAGCCTTGTCCTCC |
3: 92,224,826 (GRCm39) |
|
probably benign |
Het |
| Stradb |
A |
G |
1: 59,027,739 (GRCm39) |
I90V |
probably benign |
Het |
| Tas2r134 |
A |
G |
2: 51,518,166 (GRCm39) |
D215G |
probably damaging |
Het |
| Tbc1d4 |
T |
C |
14: 101,685,025 (GRCm39) |
K1209E |
probably damaging |
Het |
| Thbs1 |
A |
G |
2: 117,953,409 (GRCm39) |
D942G |
probably damaging |
Het |
| Tmem107 |
C |
T |
11: 68,963,633 (GRCm39) |
P139S |
probably benign |
Het |
| Tmem216 |
A |
T |
19: 10,529,266 (GRCm39) |
M40K |
probably benign |
Het |
| Tpte |
A |
G |
8: 22,845,498 (GRCm39) |
Y516C |
probably damaging |
Het |
| Trim54 |
G |
A |
5: 31,291,431 (GRCm39) |
G184D |
possibly damaging |
Het |
| Try5 |
A |
T |
6: 41,288,748 (GRCm39) |
L157Q |
probably benign |
Het |
| Ubqlnl |
G |
A |
7: 103,797,697 (GRCm39) |
A600V |
probably damaging |
Het |
| Uhrf2 |
C |
A |
19: 30,048,768 (GRCm39) |
P258Q |
probably damaging |
Het |
| Ush2a |
A |
T |
1: 188,554,885 (GRCm39) |
E3554D |
possibly damaging |
Het |
| Vmn1r121 |
T |
A |
7: 20,832,198 (GRCm39) |
R81* |
probably null |
Het |
| Vmn1r203 |
C |
A |
13: 22,708,588 (GRCm39) |
T123K |
probably benign |
Het |
| Vmn2r101 |
T |
C |
17: 19,831,654 (GRCm39) |
V550A |
probably benign |
Het |
| Wdr49 |
A |
T |
3: 75,358,193 (GRCm39) |
M184K |
probably damaging |
Het |
| Wipi2 |
A |
G |
5: 142,643,987 (GRCm39) |
N123S |
probably damaging |
Het |
| Zbtb14 |
T |
C |
17: 69,694,442 (GRCm39) |
F47L |
probably damaging |
Het |
| Zc3h7b |
C |
A |
15: 81,662,086 (GRCm39) |
S385* |
probably null |
Het |
| Zhx2 |
T |
A |
15: 57,686,658 (GRCm39) |
F676I |
probably damaging |
Het |
|
| Other mutations in Usp40 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00264:Usp40
|
APN |
1 |
87,931,960 (GRCm39) |
splice site |
probably benign |
|
|
IGL00828:Usp40
|
APN |
1 |
87,906,028 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01090:Usp40
|
APN |
1 |
87,890,187 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01123:Usp40
|
APN |
1 |
87,913,845 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01401:Usp40
|
APN |
1 |
87,921,920 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02506:Usp40
|
APN |
1 |
87,909,738 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02580:Usp40
|
APN |
1 |
87,908,688 (GRCm39) |
splice site |
probably null |
|
|
IGL02625:Usp40
|
APN |
1 |
87,877,739 (GRCm39) |
missense |
probably benign |
0.19 |
|
IGL02811:Usp40
|
APN |
1 |
87,923,458 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02958:Usp40
|
APN |
1 |
87,906,207 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Brink
|
UTSW |
1 |
87,908,755 (GRCm39) |
missense |
probably benign |
0.11 |
|
void
|
UTSW |
1 |
87,923,435 (GRCm39) |
nonsense |
probably null |
|
|
G5030:Usp40
|
UTSW |
1 |
87,921,941 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0019:Usp40
|
UTSW |
1 |
87,906,133 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0282:Usp40
|
UTSW |
1 |
87,908,680 (GRCm39) |
splice site |
probably benign |
|
|
R0453:Usp40
|
UTSW |
1 |
87,874,320 (GRCm39) |
makesense |
probably null |
|
|
R0646:Usp40
|
UTSW |
1 |
87,906,244 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1440:Usp40
|
UTSW |
1 |
87,909,808 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1490:Usp40
|
UTSW |
1 |
87,916,687 (GRCm39) |
nonsense |
probably null |
|
|
R1620:Usp40
|
UTSW |
1 |
87,921,947 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1881:Usp40
|
UTSW |
1 |
87,921,993 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1903:Usp40
|
UTSW |
1 |
87,909,778 (GRCm39) |
missense |
probably benign |
0.15 |
|
R1912:Usp40
|
UTSW |
1 |
87,874,368 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1919:Usp40
|
UTSW |
1 |
87,923,564 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R1976:Usp40
|
UTSW |
1 |
87,906,258 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2111:Usp40
|
UTSW |
1 |
87,877,936 (GRCm39) |
missense |
probably benign |
0.17 |
|
R2112:Usp40
|
UTSW |
1 |
87,877,936 (GRCm39) |
missense |
probably benign |
0.17 |
|
R2163:Usp40
|
UTSW |
1 |
87,923,580 (GRCm39) |
splice site |
probably benign |
|
|
R2432:Usp40
|
UTSW |
1 |
87,909,804 (GRCm39) |
missense |
probably benign |
|
|
R2865:Usp40
|
UTSW |
1 |
87,877,701 (GRCm39) |
nonsense |
probably null |
|
|
R3885:Usp40
|
UTSW |
1 |
87,894,991 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4360:Usp40
|
UTSW |
1 |
87,880,083 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4370:Usp40
|
UTSW |
1 |
87,925,597 (GRCm39) |
missense |
probably benign |
|
|
R4496:Usp40
|
UTSW |
1 |
87,923,459 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R4714:Usp40
|
UTSW |
1 |
87,894,901 (GRCm39) |
splice site |
probably null |
|
|
R4888:Usp40
|
UTSW |
1 |
87,913,923 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R4944:Usp40
|
UTSW |
1 |
87,880,077 (GRCm39) |
missense |
probably benign |
0.10 |
|
R5269:Usp40
|
UTSW |
1 |
87,923,504 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5629:Usp40
|
UTSW |
1 |
87,908,731 (GRCm39) |
missense |
probably benign |
|
|
R5696:Usp40
|
UTSW |
1 |
87,923,474 (GRCm39) |
missense |
probably benign |
0.27 |
|
R5756:Usp40
|
UTSW |
1 |
87,879,413 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R5887:Usp40
|
UTSW |
1 |
87,927,592 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5910:Usp40
|
UTSW |
1 |
87,896,122 (GRCm39) |
nonsense |
probably null |
|
|
R6014:Usp40
|
UTSW |
1 |
87,907,738 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6044:Usp40
|
UTSW |
1 |
87,917,872 (GRCm39) |
missense |
probably benign |
|
|
R6083:Usp40
|
UTSW |
1 |
87,906,281 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6299:Usp40
|
UTSW |
1 |
87,925,649 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6625:Usp40
|
UTSW |
1 |
87,894,935 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6757:Usp40
|
UTSW |
1 |
87,907,759 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6810:Usp40
|
UTSW |
1 |
87,908,755 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7110:Usp40
|
UTSW |
1 |
87,913,884 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7573:Usp40
|
UTSW |
1 |
87,913,794 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7634:Usp40
|
UTSW |
1 |
87,890,152 (GRCm39) |
nonsense |
probably null |
|
|
R7756:Usp40
|
UTSW |
1 |
87,894,922 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7767:Usp40
|
UTSW |
1 |
87,909,900 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7861:Usp40
|
UTSW |
1 |
87,909,852 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7881:Usp40
|
UTSW |
1 |
87,923,435 (GRCm39) |
nonsense |
probably null |
|
|
R7896:Usp40
|
UTSW |
1 |
87,906,201 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R8119:Usp40
|
UTSW |
1 |
87,895,400 (GRCm39) |
splice site |
probably null |
|
|
R8354:Usp40
|
UTSW |
1 |
87,908,694 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8358:Usp40
|
UTSW |
1 |
87,908,770 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R8425:Usp40
|
UTSW |
1 |
87,887,558 (GRCm39) |
missense |
probably benign |
|
|
R8446:Usp40
|
UTSW |
1 |
87,906,190 (GRCm39) |
missense |
probably benign |
|
|
R8454:Usp40
|
UTSW |
1 |
87,908,694 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8744:Usp40
|
UTSW |
1 |
87,911,491 (GRCm39) |
missense |
probably benign |
|
|
R9002:Usp40
|
UTSW |
1 |
87,935,063 (GRCm39) |
missense |
probably benign |
|
|
R9033:Usp40
|
UTSW |
1 |
87,923,499 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R9210:Usp40
|
UTSW |
1 |
87,885,035 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9245:Usp40
|
UTSW |
1 |
87,878,009 (GRCm39) |
missense |
probably benign |
|
|
R9331:Usp40
|
UTSW |
1 |
87,901,828 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9378:Usp40
|
UTSW |
1 |
87,885,032 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9379:Usp40
|
UTSW |
1 |
87,881,889 (GRCm39) |
missense |
probably benign |
|
|
R9501:Usp40
|
UTSW |
1 |
87,925,557 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9535:Usp40
|
UTSW |
1 |
87,935,161 (GRCm39) |
start gained |
probably benign |
|
|
R9537:Usp40
|
UTSW |
1 |
87,935,117 (GRCm39) |
missense |
probably benign |
0.01 |
|
RF006:Usp40
|
UTSW |
1 |
87,894,917 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
Z1177:Usp40
|
UTSW |
1 |
87,896,136 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGGAAGTCAAATCTCGTTGAGGATG -3'
(R):5'- GTAAGTTGGGCTTTCTCAGGAAAC -3'
Sequencing Primer
(F):5'- AGGATGGTTGTGAGCCACC -3'
(R):5'- GAAACCAGGCTCTCTCTGACTG -3'
|
| Posted On |
2019-10-24 |
Incidental Mutation