Incidental Mutation 'R7583:Ncapd3'
| ID |
586893 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ncapd3
|
| Ensembl Gene |
ENSMUSG00000035024 |
| Gene Name |
non-SMC condensin II complex, subunit D3 |
| Synonyms |
4632407J06Rik, 2810487N22Rik, B130055D15Rik |
| MMRRC Submission |
045666-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.963)
|
| Stock # |
R7583 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
9 |
| Chromosomal Location |
26941471-27006611 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to T
at 26983144 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Cysteine to Phenylalanine
at position 964
(C964F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000083374
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000073127]
[ENSMUST00000086198]
[ENSMUST00000216677]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000073127
AA Change: C964F
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000072871
Gene: ENSMUSG00000035024
AA Change: C964F
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
159 |
170 |
N/A |
INTRINSIC |
|
low complexity region
|
173 |
184 |
N/A |
INTRINSIC |
|
Pfam:Cnd1
|
949 |
1148 |
1.7e-46 |
PFAM |
|
low complexity region
|
1192 |
1200 |
N/A |
INTRINSIC |
|
coiled coil region
|
1213 |
1270 |
N/A |
INTRINSIC |
|
low complexity region
|
1290 |
1315 |
N/A |
INTRINSIC |
|
low complexity region
|
1393 |
1410 |
N/A |
INTRINSIC |
|
low complexity region
|
1485 |
1498 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000086198
AA Change: C964F
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000083374
Gene: ENSMUSG00000035024
AA Change: C964F
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
159 |
170 |
N/A |
INTRINSIC |
|
low complexity region
|
173 |
184 |
N/A |
INTRINSIC |
|
Pfam:Cohesin_HEAT
|
536 |
560 |
4.6e-5 |
PFAM |
|
Pfam:Cnd1
|
949 |
1148 |
6.6e-59 |
PFAM |
|
low complexity region
|
1192 |
1200 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000216677
AA Change: C964F
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 98.9%
|
| Validation Efficiency |
99% (95/96) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Condensin complexes I and II play essential roles in mitotic chromosome assembly and segregation. Both condensins contain 2 invariant structural maintenance of chromosome (SMC) subunits, SMC2 (MIM 605576) and SMC4 (MIM 605575), but they contain different sets of non-SMC subunits. NCAPD3 is 1 of 3 non-SMC subunits that define condensin II (Ono et al., 2003 [PubMed 14532007]).[supplied by OMIM, Mar 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 98 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4932414N04Rik |
A |
T |
2: 68,569,670 (GRCm39) |
D462V |
probably damaging |
Het |
| Abcc1 |
T |
C |
16: 14,221,902 (GRCm39) |
W222R |
probably damaging |
Het |
| Adamts13 |
A |
G |
2: 26,863,965 (GRCm39) |
K48E |
probably benign |
Het |
| Adgrd1 |
A |
C |
5: 129,256,652 (GRCm39) |
T674P |
probably benign |
Het |
| Agbl4 |
A |
T |
4: 110,976,150 (GRCm39) |
Y169F |
possibly damaging |
Het |
| Ahnak |
T |
A |
19: 8,983,457 (GRCm39) |
N1580K |
possibly damaging |
Het |
| Angptl8 |
A |
C |
9: 21,747,210 (GRCm39) |
|
probably null |
Het |
| Ap3d1 |
G |
A |
10: 80,545,292 (GRCm39) |
T1053I |
probably benign |
Het |
| Atad2 |
T |
C |
15: 57,990,060 (GRCm39) |
T139A |
probably benign |
Het |
| Bdp1 |
T |
A |
13: 100,186,320 (GRCm39) |
T1711S |
probably damaging |
Het |
| Bod1l |
T |
C |
5: 41,991,133 (GRCm39) |
I141V |
probably damaging |
Het |
| Cavin2 |
A |
T |
1: 51,328,777 (GRCm39) |
N78I |
possibly damaging |
Het |
| Ccnb1 |
T |
C |
13: 100,916,262 (GRCm39) |
H406R |
probably benign |
Het |
| Cd200r4 |
A |
G |
16: 44,653,784 (GRCm39) |
T194A |
probably damaging |
Het |
| Cdt1 |
G |
A |
8: 123,296,995 (GRCm39) |
R263H |
probably damaging |
Het |
| Cep85l |
A |
T |
10: 53,157,450 (GRCm39) |
I751N |
probably damaging |
Het |
| Clasp2 |
A |
G |
9: 113,737,755 (GRCm39) |
D1043G |
probably benign |
Het |
| Cmip |
A |
T |
8: 118,181,691 (GRCm39) |
N578I |
probably damaging |
Het |
| Col2a1 |
T |
G |
15: 97,874,065 (GRCm39) |
K1440N |
unknown |
Het |
| Cpne2 |
A |
T |
8: 95,282,209 (GRCm39) |
M252L |
probably benign |
Het |
| Crb2 |
A |
G |
2: 37,680,607 (GRCm39) |
T512A |
probably benign |
Het |
| Csmd1 |
A |
G |
8: 16,048,833 (GRCm39) |
Y2290H |
probably damaging |
Het |
| Ctnnd1 |
A |
T |
2: 84,442,405 (GRCm39) |
D642E |
probably damaging |
Het |
| Ctns |
A |
G |
11: 73,079,296 (GRCm39) |
S141P |
probably benign |
Het |
| Cwh43 |
A |
G |
5: 73,591,632 (GRCm39) |
Q575R |
probably benign |
Het |
| Cyp2b19 |
C |
A |
7: 26,458,489 (GRCm39) |
T68K |
probably damaging |
Het |
| Dcaf6 |
A |
G |
1: 165,160,879 (GRCm39) |
S849P |
probably damaging |
Het |
| Dnm3 |
T |
A |
1: 162,305,343 (GRCm39) |
Q17L |
possibly damaging |
Het |
| Enpp3 |
A |
T |
10: 24,711,990 (GRCm39) |
M1K |
probably null |
Het |
| Fam124a |
T |
A |
14: 62,844,008 (GRCm39) |
C505* |
probably null |
Het |
| Fhip2a |
T |
A |
19: 57,367,034 (GRCm39) |
D192E |
probably benign |
Het |
| Fsip2 |
A |
G |
2: 82,805,585 (GRCm39) |
I635V |
probably benign |
Het |
| Gm5878 |
A |
T |
6: 85,095,682 (GRCm39) |
|
probably null |
Het |
| Gpld1 |
C |
A |
13: 25,159,743 (GRCm39) |
A437D |
probably damaging |
Het |
| Grk5 |
G |
T |
19: 61,071,642 (GRCm39) |
V401L |
possibly damaging |
Het |
| Gucy2g |
A |
T |
19: 55,224,047 (GRCm39) |
L259Q |
probably damaging |
Het |
| Habp2 |
T |
A |
19: 56,300,236 (GRCm39) |
D191E |
probably benign |
Het |
| Helz2 |
T |
A |
2: 180,879,365 (GRCm39) |
H751L |
probably benign |
Het |
| Hgsnat |
A |
G |
8: 26,461,592 (GRCm39) |
|
probably null |
Het |
| Hivep1 |
T |
A |
13: 42,317,716 (GRCm39) |
V2064E |
probably damaging |
Het |
| Ikbke |
C |
T |
1: 131,204,216 (GRCm39) |
A26T |
probably damaging |
Het |
| Ivd |
C |
A |
2: 118,692,612 (GRCm39) |
D37E |
probably damaging |
Het |
| Kif26b |
G |
A |
1: 178,358,010 (GRCm39) |
W40* |
probably null |
Het |
| Klrc2 |
A |
G |
6: 129,636,274 (GRCm39) |
S114P |
probably damaging |
Het |
| Lama1 |
A |
T |
17: 68,068,616 (GRCm39) |
T772S |
|
Het |
| Lamc1 |
T |
A |
1: 153,118,978 (GRCm39) |
K880N |
possibly damaging |
Het |
| Lmf1 |
G |
A |
17: 25,874,423 (GRCm39) |
D12N |
|
Het |
| Lpin2 |
G |
T |
17: 71,538,391 (GRCm39) |
E384* |
probably null |
Het |
| Lrrc23 |
T |
C |
6: 124,756,541 (GRCm39) |
|
probably benign |
Het |
| Lrrc31 |
T |
C |
3: 30,745,248 (GRCm39) |
|
probably null |
Het |
| Luc7l2 |
A |
G |
6: 38,528,820 (GRCm39) |
Q13R |
probably damaging |
Het |
| Ly6c1 |
G |
T |
15: 74,920,346 (GRCm39) |
H5Q |
probably damaging |
Het |
| Lyst |
A |
T |
13: 13,810,472 (GRCm39) |
H714L |
probably damaging |
Het |
| Man2a2 |
C |
T |
7: 80,016,692 (GRCm39) |
R374H |
probably damaging |
Het |
| Mchr1 |
A |
T |
15: 81,121,642 (GRCm39) |
T131S |
probably benign |
Het |
| Msto1 |
T |
C |
3: 88,820,236 (GRCm39) |
|
probably null |
Het |
| Myh1 |
C |
T |
11: 67,111,739 (GRCm39) |
T1698I |
probably benign |
Het |
| Nefh |
T |
C |
11: 4,891,089 (GRCm39) |
E510G |
probably damaging |
Het |
| Or10g3b |
T |
C |
14: 52,587,360 (GRCm39) |
T48A |
possibly damaging |
Het |
| Or13a24 |
A |
G |
7: 140,154,123 (GRCm39) |
E19G |
probably benign |
Het |
| Or1b1 |
A |
T |
2: 36,995,539 (GRCm39) |
L41* |
probably null |
Het |
| Or1q1 |
A |
C |
2: 36,887,092 (GRCm39) |
K90T |
probably damaging |
Het |
| Or4a73 |
A |
T |
2: 89,421,095 (GRCm39) |
Y121* |
probably null |
Het |
| P4ha1 |
T |
A |
10: 59,205,462 (GRCm39) |
S497R |
probably benign |
Het |
| Palb2 |
T |
C |
7: 121,726,565 (GRCm39) |
D435G |
probably benign |
Het |
| Papola |
C |
T |
12: 105,777,304 (GRCm39) |
P282L |
probably damaging |
Het |
| Pcdhgb1 |
A |
G |
18: 37,815,377 (GRCm39) |
R623G |
probably damaging |
Het |
| Pcolce |
T |
G |
5: 137,605,707 (GRCm39) |
K229Q |
probably benign |
Het |
| Pkhd1l1 |
T |
C |
15: 44,431,760 (GRCm39) |
|
probably null |
Het |
| Ppp6r3 |
T |
A |
19: 3,540,790 (GRCm39) |
T443S |
probably benign |
Het |
| Pramel58 |
A |
T |
5: 94,830,753 (GRCm39) |
T84S |
possibly damaging |
Het |
| Psg20 |
T |
A |
7: 18,416,408 (GRCm39) |
D236V |
probably damaging |
Het |
| Ptgr2 |
T |
G |
12: 84,355,179 (GRCm39) |
S304R |
probably damaging |
Het |
| Ptpn22 |
A |
T |
3: 103,809,430 (GRCm39) |
D681V |
probably benign |
Het |
| Rab3gap1 |
T |
C |
1: 127,858,612 (GRCm39) |
S574P |
probably benign |
Het |
| Slc36a1 |
A |
G |
11: 55,104,754 (GRCm39) |
|
probably null |
Het |
| Slc9a5 |
A |
G |
8: 106,089,904 (GRCm39) |
S621G |
possibly damaging |
Het |
| Sntg1 |
A |
G |
1: 8,515,249 (GRCm39) |
|
probably null |
Het |
| Snx17 |
A |
G |
5: 31,353,877 (GRCm39) |
N222D |
possibly damaging |
Het |
| Spata19 |
G |
T |
9: 27,311,729 (GRCm39) |
S116I |
possibly damaging |
Het |
| Spn |
G |
A |
7: 126,736,234 (GRCm39) |
A91V |
probably damaging |
Het |
| Srrm3 |
T |
C |
5: 135,881,135 (GRCm39) |
V145A |
probably benign |
Het |
| St7 |
A |
T |
6: 17,942,753 (GRCm39) |
T575S |
possibly damaging |
Het |
| Taf2 |
A |
T |
15: 54,928,072 (GRCm39) |
Y110* |
probably null |
Het |
| Tcf20 |
T |
C |
15: 82,739,477 (GRCm39) |
E658G |
possibly damaging |
Het |
| Tdrd6 |
G |
T |
17: 43,935,129 (GRCm39) |
A1973E |
probably benign |
Het |
| Tg |
T |
G |
15: 66,636,267 (GRCm39) |
L2237W |
probably damaging |
Het |
| Ticrr |
C |
A |
7: 79,346,487 (GRCm39) |
Y1882* |
probably null |
Het |
| Trim45 |
T |
A |
3: 100,832,339 (GRCm39) |
C191S |
probably damaging |
Het |
| Upf3a |
G |
A |
8: 13,835,889 (GRCm39) |
|
probably null |
Het |
| Vmn2r42 |
A |
T |
7: 8,197,740 (GRCm39) |
L293* |
probably null |
Het |
| Vmn2r62 |
T |
A |
7: 42,437,466 (GRCm39) |
Q339H |
possibly damaging |
Het |
| Wdr24 |
A |
T |
17: 26,044,804 (GRCm39) |
R220W |
probably null |
Het |
| Wdr5 |
T |
A |
2: 27,408,787 (GRCm39) |
S22T |
probably benign |
Het |
| Zfp37 |
G |
A |
4: 62,110,253 (GRCm39) |
|
probably benign |
Het |
| Zfp735 |
A |
T |
11: 73,601,933 (GRCm39) |
L292F |
possibly damaging |
Het |
| Zfp985 |
T |
A |
4: 147,667,946 (GRCm39) |
C271* |
probably null |
Het |
| Zranb1 |
G |
A |
7: 132,585,625 (GRCm39) |
R691Q |
probably benign |
Het |
|
| Other mutations in Ncapd3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00339:Ncapd3
|
APN |
9 |
26,963,649 (GRCm39) |
missense |
probably benign |
|
|
IGL00544:Ncapd3
|
APN |
9 |
26,974,634 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01657:Ncapd3
|
APN |
9 |
26,983,120 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL01979:Ncapd3
|
APN |
9 |
26,983,261 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02073:Ncapd3
|
APN |
9 |
26,974,612 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02083:Ncapd3
|
APN |
9 |
26,963,117 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02383:Ncapd3
|
APN |
9 |
26,961,624 (GRCm39) |
missense |
probably benign |
0.44 |
|
IGL02429:Ncapd3
|
APN |
9 |
27,000,598 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL02437:Ncapd3
|
APN |
9 |
26,975,264 (GRCm39) |
splice site |
probably benign |
|
|
IGL02861:Ncapd3
|
APN |
9 |
26,981,195 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03202:Ncapd3
|
APN |
9 |
26,983,011 (GRCm39) |
splice site |
probably benign |
|
|
IGL03219:Ncapd3
|
APN |
9 |
26,975,169 (GRCm39) |
splice site |
probably benign |
|
|
IGL03252:Ncapd3
|
APN |
9 |
26,962,745 (GRCm39) |
missense |
probably damaging |
1.00 |
|
pevensie
|
UTSW |
9 |
26,997,342 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0015:Ncapd3
|
UTSW |
9 |
26,963,105 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0015:Ncapd3
|
UTSW |
9 |
26,963,105 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0084:Ncapd3
|
UTSW |
9 |
26,967,407 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0491:Ncapd3
|
UTSW |
9 |
26,969,179 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0513:Ncapd3
|
UTSW |
9 |
26,975,401 (GRCm39) |
splice site |
probably benign |
|
|
R0565:Ncapd3
|
UTSW |
9 |
26,999,294 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0601:Ncapd3
|
UTSW |
9 |
26,952,803 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0671:Ncapd3
|
UTSW |
9 |
26,998,773 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0673:Ncapd3
|
UTSW |
9 |
26,998,773 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0842:Ncapd3
|
UTSW |
9 |
26,948,380 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1178:Ncapd3
|
UTSW |
9 |
26,952,717 (GRCm39) |
missense |
probably benign |
|
|
R1366:Ncapd3
|
UTSW |
9 |
26,969,236 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1432:Ncapd3
|
UTSW |
9 |
26,981,168 (GRCm39) |
splice site |
probably benign |
|
|
R1439:Ncapd3
|
UTSW |
9 |
26,998,862 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1532:Ncapd3
|
UTSW |
9 |
26,994,656 (GRCm39) |
nonsense |
probably null |
|
|
R2131:Ncapd3
|
UTSW |
9 |
26,994,642 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2178:Ncapd3
|
UTSW |
9 |
26,999,845 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2238:Ncapd3
|
UTSW |
9 |
26,978,320 (GRCm39) |
missense |
probably benign |
|
|
R2258:Ncapd3
|
UTSW |
9 |
26,967,368 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2259:Ncapd3
|
UTSW |
9 |
26,967,368 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2260:Ncapd3
|
UTSW |
9 |
26,967,368 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2297:Ncapd3
|
UTSW |
9 |
26,952,797 (GRCm39) |
nonsense |
probably null |
|
|
R2877:Ncapd3
|
UTSW |
9 |
26,955,783 (GRCm39) |
splice site |
probably null |
|
|
R3612:Ncapd3
|
UTSW |
9 |
26,961,653 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3709:Ncapd3
|
UTSW |
9 |
26,963,645 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3791:Ncapd3
|
UTSW |
9 |
26,963,931 (GRCm39) |
missense |
probably benign |
0.27 |
|
R4052:Ncapd3
|
UTSW |
9 |
27,000,679 (GRCm39) |
splice site |
probably null |
|
|
R4297:Ncapd3
|
UTSW |
9 |
26,963,623 (GRCm39) |
missense |
probably benign |
|
|
R4299:Ncapd3
|
UTSW |
9 |
26,963,623 (GRCm39) |
missense |
probably benign |
|
|
R4441:Ncapd3
|
UTSW |
9 |
26,962,941 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R4572:Ncapd3
|
UTSW |
9 |
27,005,911 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4675:Ncapd3
|
UTSW |
9 |
27,006,038 (GRCm39) |
unclassified |
probably benign |
|
|
R4790:Ncapd3
|
UTSW |
9 |
26,963,146 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4835:Ncapd3
|
UTSW |
9 |
26,997,342 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4919:Ncapd3
|
UTSW |
9 |
26,963,071 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4928:Ncapd3
|
UTSW |
9 |
26,983,031 (GRCm39) |
nonsense |
probably null |
|
|
R4939:Ncapd3
|
UTSW |
9 |
26,975,165 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4980:Ncapd3
|
UTSW |
9 |
26,974,591 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5030:Ncapd3
|
UTSW |
9 |
26,983,062 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5052:Ncapd3
|
UTSW |
9 |
26,963,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5180:Ncapd3
|
UTSW |
9 |
26,962,941 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5343:Ncapd3
|
UTSW |
9 |
26,999,349 (GRCm39) |
small deletion |
probably benign |
|
|
R5656:Ncapd3
|
UTSW |
9 |
26,962,941 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5840:Ncapd3
|
UTSW |
9 |
27,006,054 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5900:Ncapd3
|
UTSW |
9 |
26,978,265 (GRCm39) |
missense |
probably benign |
0.26 |
|
R6093:Ncapd3
|
UTSW |
9 |
26,967,454 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6122:Ncapd3
|
UTSW |
9 |
26,975,278 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6249:Ncapd3
|
UTSW |
9 |
26,999,349 (GRCm39) |
small deletion |
probably benign |
|
|
R6428:Ncapd3
|
UTSW |
9 |
26,963,960 (GRCm39) |
splice site |
probably null |
|
|
R6432:Ncapd3
|
UTSW |
9 |
26,955,805 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6441:Ncapd3
|
UTSW |
9 |
26,974,712 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6459:Ncapd3
|
UTSW |
9 |
26,963,051 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6567:Ncapd3
|
UTSW |
9 |
26,978,300 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R6722:Ncapd3
|
UTSW |
9 |
26,998,852 (GRCm39) |
missense |
probably benign |
|
|
R6862:Ncapd3
|
UTSW |
9 |
26,942,105 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7234:Ncapd3
|
UTSW |
9 |
26,961,655 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7286:Ncapd3
|
UTSW |
9 |
26,981,254 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7404:Ncapd3
|
UTSW |
9 |
26,978,315 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7541:Ncapd3
|
UTSW |
9 |
26,978,336 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7655:Ncapd3
|
UTSW |
9 |
26,966,801 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R7656:Ncapd3
|
UTSW |
9 |
26,966,801 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R7815:Ncapd3
|
UTSW |
9 |
26,974,736 (GRCm39) |
nonsense |
probably null |
|
|
R7876:Ncapd3
|
UTSW |
9 |
26,956,519 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7913:Ncapd3
|
UTSW |
9 |
26,959,522 (GRCm39) |
nonsense |
probably null |
|
|
R8068:Ncapd3
|
UTSW |
9 |
26,974,657 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R8147:Ncapd3
|
UTSW |
9 |
26,942,014 (GRCm39) |
start gained |
probably benign |
|
|
R8197:Ncapd3
|
UTSW |
9 |
26,997,329 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8264:Ncapd3
|
UTSW |
9 |
27,006,038 (GRCm39) |
unclassified |
probably benign |
|
|
R8353:Ncapd3
|
UTSW |
9 |
26,983,100 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8539:Ncapd3
|
UTSW |
9 |
26,959,520 (GRCm39) |
missense |
probably benign |
|
|
R8839:Ncapd3
|
UTSW |
9 |
27,005,730 (GRCm39) |
missense |
|
|
|
R8917:Ncapd3
|
UTSW |
9 |
26,999,297 (GRCm39) |
missense |
probably benign |
|
|
R8997:Ncapd3
|
UTSW |
9 |
26,959,577 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9215:Ncapd3
|
UTSW |
9 |
26,975,386 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R9393:Ncapd3
|
UTSW |
9 |
26,962,682 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R9412:Ncapd3
|
UTSW |
9 |
26,967,451 (GRCm39) |
nonsense |
probably null |
|
|
R9688:Ncapd3
|
UTSW |
9 |
26,967,349 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9746:Ncapd3
|
UTSW |
9 |
26,974,655 (GRCm39) |
missense |
probably benign |
|
|
R9749:Ncapd3
|
UTSW |
9 |
26,956,873 (GRCm39) |
missense |
probably benign |
0.14 |
|
| Predicted Primers |
PCR Primer
(F):5'- CCATTTTGTGGGTAAGTAGGTAAC -3'
(R):5'- TCCTTAAGCCAGCAATGGTG -3'
Sequencing Primer
(F):5'- ATTGTTGCAAAGGTATGTGATAGAG -3'
(R):5'- CAGCAATGGTGGAGCAGAAC -3'
|
| Posted On |
2019-10-24 |
Incidental Mutation