Incidental Mutation 'R0624:Patj'
| ID |
58786 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Patj
|
| Ensembl Gene |
ENSMUSG00000061859 |
| Gene Name |
PATJ, crumbs cell polarity complex component |
| Synonyms |
Cipp, Inadl |
| MMRRC Submission |
038813-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0624 (G1)
|
| Quality Score |
205 |
|
Status
|
Validated
|
| Chromosome |
4 |
| Chromosomal Location |
98284022-98607840 bp(+) (GRCm39) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
T to C
at 98569472 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000102644
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000030290]
[ENSMUST00000041284]
[ENSMUST00000102792]
[ENSMUST00000107029]
|
| AlphaFold |
Q63ZW7 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000030290
|
| SMART Domains |
Protein: ENSMUSP00000030290
Gene: ENSMUSG00000061859
| Domain | Start | End | E-Value | Type |
|---|
|
PDZ
|
31 |
106 |
6.12e-19 |
SMART |
|
low complexity region
|
134 |
144 |
N/A |
INTRINSIC |
|
low complexity region
|
188 |
206 |
N/A |
INTRINSIC |
|
PDZ
|
258 |
333 |
4.36e-24 |
SMART |
|
PDZ
|
355 |
428 |
2.49e-19 |
SMART |
|
PDZ
|
496 |
573 |
1.73e-18 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000041284
|
| SMART Domains |
Protein: ENSMUSP00000049176
Gene: ENSMUSG00000061859
| Domain | Start | End | E-Value | Type |
|---|
|
L27
|
8 |
68 |
6.53e-9 |
SMART |
|
PDZ
|
143 |
221 |
1.78e-20 |
SMART |
|
PDZ
|
256 |
328 |
1.15e-23 |
SMART |
|
PDZ
|
374 |
453 |
3.15e-21 |
SMART |
|
coiled coil region
|
486 |
513 |
N/A |
INTRINSIC |
|
PDZ
|
570 |
641 |
1.28e-12 |
SMART |
|
PDZ
|
696 |
775 |
9.5e-16 |
SMART |
|
low complexity region
|
980 |
991 |
N/A |
INTRINSIC |
|
low complexity region
|
1054 |
1062 |
N/A |
INTRINSIC |
|
PDZ
|
1083 |
1166 |
8.65e-19 |
SMART |
|
PDZ
|
1253 |
1328 |
6.12e-19 |
SMART |
|
low complexity region
|
1356 |
1366 |
N/A |
INTRINSIC |
|
low complexity region
|
1410 |
1428 |
N/A |
INTRINSIC |
|
PDZ
|
1480 |
1555 |
4.36e-24 |
SMART |
|
PDZ
|
1577 |
1650 |
2.49e-19 |
SMART |
|
PDZ
|
1718 |
1795 |
2.13e-18 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000102792
|
| SMART Domains |
Protein: ENSMUSP00000099854
Gene: ENSMUSG00000061859
| Domain | Start | End | E-Value | Type |
|---|
|
PDZ
|
31 |
106 |
6.12e-19 |
SMART |
|
low complexity region
|
134 |
144 |
N/A |
INTRINSIC |
|
low complexity region
|
188 |
206 |
N/A |
INTRINSIC |
|
PDZ
|
258 |
333 |
4.36e-24 |
SMART |
|
PDZ
|
355 |
428 |
2.49e-19 |
SMART |
|
PDZ
|
496 |
573 |
2.13e-18 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000107029
|
| SMART Domains |
Protein: ENSMUSP00000102644
Gene: ENSMUSG00000061859
| Domain | Start | End | E-Value | Type |
|---|
|
PDZ
|
1 |
68 |
1e-9 |
SMART |
|
PDZ
|
123 |
202 |
4.7e-18 |
SMART |
|
low complexity region
|
407 |
418 |
N/A |
INTRINSIC |
|
low complexity region
|
481 |
489 |
N/A |
INTRINSIC |
|
PDZ
|
510 |
593 |
4.3e-21 |
SMART |
|
PDZ
|
680 |
755 |
2.9e-21 |
SMART |
|
low complexity region
|
783 |
793 |
N/A |
INTRINSIC |
|
low complexity region
|
837 |
855 |
N/A |
INTRINSIC |
|
PDZ
|
907 |
982 |
2.2e-26 |
SMART |
|
PDZ
|
1004 |
1077 |
1.2e-21 |
SMART |
|
PDZ
|
1145 |
1222 |
1e-20 |
SMART |
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.4%
- 3x: 99.0%
- 10x: 97.8%
- 20x: 96.2%
|
| Validation Efficiency |
98% (88/90) |
| MGI Phenotype |
FUNCTION: This gene encodes a multivalent PDZ domain protein, which is expressed exclusively in brain and kidney. This protein selectively interacts with inward rectifier K+ (Kir) family members, N-methyl-D-aspartate receptor subunits, neurexins and neuroligins, as well as cell surface molecules enriched in synaptic membranes. Thus, this protein may serve as a scaffold that brings structurally diverse but functionally connected proteins into close proximity at the synapse. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
All alleles(5) : Gene trapped(5) |
| Other mutations in this stock |
Total: 88 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca9 |
T |
A |
11: 110,030,446 (GRCm39) |
D767V |
probably damaging |
Het |
| Add1 |
T |
A |
5: 34,763,197 (GRCm39) |
N128K |
probably damaging |
Het |
| Ado |
A |
T |
10: 67,384,058 (GRCm39) |
D182E |
probably benign |
Het |
| Anapc4 |
T |
A |
5: 53,002,761 (GRCm39) |
|
probably benign |
Het |
| Ano10 |
A |
G |
9: 122,088,661 (GRCm39) |
|
probably benign |
Het |
| Apba2 |
A |
G |
7: 64,364,263 (GRCm39) |
|
probably null |
Het |
| Apc2 |
A |
G |
10: 80,150,417 (GRCm39) |
T1795A |
probably benign |
Het |
| Atp4a |
A |
G |
7: 30,418,424 (GRCm39) |
N571D |
probably benign |
Het |
| Birc6 |
A |
G |
17: 74,887,344 (GRCm39) |
N891D |
probably benign |
Het |
| Bltp2 |
G |
A |
11: 78,159,283 (GRCm39) |
E494K |
probably damaging |
Het |
| Car3 |
G |
T |
3: 14,931,864 (GRCm39) |
M78I |
probably benign |
Het |
| Cc2d2a |
A |
T |
5: 43,887,371 (GRCm39) |
H1267L |
probably benign |
Het |
| Cdk18 |
A |
G |
1: 132,046,610 (GRCm39) |
L192P |
probably damaging |
Het |
| Cdk9 |
A |
T |
2: 32,599,836 (GRCm39) |
Y134N |
probably damaging |
Het |
| Ceacam5 |
A |
T |
7: 17,448,888 (GRCm39) |
T85S |
probably benign |
Het |
| Cenpe |
A |
G |
3: 134,952,347 (GRCm39) |
T1403A |
probably benign |
Het |
| Chd8 |
C |
T |
14: 52,457,214 (GRCm39) |
G918D |
possibly damaging |
Het |
| Csnk1e |
T |
A |
15: 79,304,098 (GRCm39) |
|
probably benign |
Het |
| Dctpp1 |
A |
T |
7: 126,856,365 (GRCm39) |
I119N |
probably damaging |
Het |
| Defb34 |
T |
A |
8: 19,173,784 (GRCm39) |
F6Y |
unknown |
Het |
| Dnai4 |
T |
C |
4: 102,930,054 (GRCm39) |
|
probably benign |
Het |
| Dvl1 |
C |
G |
4: 155,939,232 (GRCm39) |
N248K |
probably damaging |
Het |
| Dync1h1 |
T |
C |
12: 110,618,181 (GRCm39) |
|
probably benign |
Het |
| Dync2i1 |
T |
C |
12: 116,211,910 (GRCm39) |
D199G |
probably damaging |
Het |
| Eml5 |
T |
A |
12: 98,831,738 (GRCm39) |
R407W |
probably damaging |
Het |
| Epb41l5 |
T |
C |
1: 119,551,688 (GRCm39) |
D99G |
probably damaging |
Het |
| Fat1 |
A |
T |
8: 45,504,205 (GRCm39) |
N4566I |
possibly damaging |
Het |
| Gm21834 |
T |
C |
17: 58,049,015 (GRCm39) |
E67G |
possibly damaging |
Het |
| Gsap |
T |
A |
5: 21,458,949 (GRCm39) |
|
probably null |
Het |
| Guf1 |
T |
C |
5: 69,715,923 (GRCm39) |
I108T |
probably damaging |
Het |
| Hsd3b5 |
T |
C |
3: 98,526,720 (GRCm39) |
D242G |
probably damaging |
Het |
| Kcna7 |
A |
G |
7: 45,059,114 (GRCm39) |
D467G |
probably null |
Het |
| Lars1 |
A |
G |
18: 42,375,849 (GRCm39) |
|
probably benign |
Het |
| Lrrc56 |
A |
T |
7: 140,786,366 (GRCm39) |
D248V |
probably damaging |
Het |
| Map3k14 |
T |
A |
11: 103,133,117 (GRCm39) |
E27V |
possibly damaging |
Het |
| Med12l |
G |
A |
3: 58,945,123 (GRCm39) |
W116* |
probably null |
Het |
| Mgll |
A |
G |
6: 88,702,799 (GRCm39) |
R33G |
probably damaging |
Het |
| Mmp13 |
A |
G |
9: 7,280,221 (GRCm39) |
S384G |
possibly damaging |
Het |
| Nalcn |
C |
T |
14: 123,607,444 (GRCm39) |
C675Y |
probably benign |
Het |
| Nrxn1 |
A |
G |
17: 91,396,117 (GRCm39) |
L13P |
unknown |
Het |
| Ocstamp |
A |
G |
2: 165,239,772 (GRCm39) |
V138A |
probably damaging |
Het |
| Or12e8 |
T |
G |
2: 87,188,026 (GRCm39) |
Y79* |
probably null |
Het |
| Or2z8 |
T |
A |
8: 72,812,006 (GRCm39) |
S161T |
possibly damaging |
Het |
| Or4a68 |
A |
G |
2: 89,270,482 (GRCm39) |
V47A |
possibly damaging |
Het |
| Or4f7 |
T |
C |
2: 111,645,056 (GRCm39) |
N5S |
probably damaging |
Het |
| Or5p51 |
A |
G |
7: 107,444,323 (GRCm39) |
S206P |
possibly damaging |
Het |
| Or9i1b |
T |
G |
19: 13,896,808 (GRCm39) |
C141W |
probably damaging |
Het |
| Pcdhb22 |
A |
G |
18: 37,651,780 (GRCm39) |
I83V |
probably benign |
Het |
| Pclo |
A |
G |
5: 14,719,670 (GRCm39) |
E1269G |
unknown |
Het |
| Plagl2 |
T |
C |
2: 153,077,973 (GRCm39) |
T3A |
probably benign |
Het |
| Plcb1 |
C |
T |
2: 135,136,831 (GRCm39) |
P309S |
possibly damaging |
Het |
| Pld3 |
A |
T |
7: 27,239,000 (GRCm39) |
L175Q |
possibly damaging |
Het |
| Prrx1 |
A |
G |
1: 163,075,974 (GRCm39) |
|
probably benign |
Het |
| Psap |
T |
G |
10: 60,135,345 (GRCm39) |
|
probably benign |
Het |
| Ptgfr |
G |
A |
3: 151,540,839 (GRCm39) |
T223M |
probably damaging |
Het |
| Reep2 |
A |
T |
18: 34,973,824 (GRCm39) |
I6F |
probably benign |
Het |
| Rraga |
A |
G |
4: 86,494,454 (GRCm39) |
E100G |
probably benign |
Het |
| Rrm2b |
T |
C |
15: 37,931,889 (GRCm39) |
D37G |
probably benign |
Het |
| Rtl1 |
T |
C |
12: 109,559,153 (GRCm39) |
I895M |
probably damaging |
Het |
| Ryr1 |
G |
A |
7: 28,774,034 (GRCm39) |
A2445V |
probably damaging |
Het |
| Sbf1 |
C |
T |
15: 89,186,532 (GRCm39) |
D898N |
possibly damaging |
Het |
| Sh3d19 |
G |
A |
3: 86,022,213 (GRCm39) |
V548I |
possibly damaging |
Het |
| Shf |
C |
A |
2: 122,199,116 (GRCm39) |
|
probably benign |
Het |
| Sipa1l3 |
T |
C |
7: 29,086,676 (GRCm39) |
E638G |
probably damaging |
Het |
| Slc13a3 |
G |
T |
2: 165,253,807 (GRCm39) |
P449T |
probably damaging |
Het |
| Slc2a13 |
C |
T |
15: 91,234,215 (GRCm39) |
V374I |
possibly damaging |
Het |
| Slc4a7 |
T |
C |
14: 14,794,059 (GRCm38) |
|
probably null |
Het |
| Slc7a2 |
T |
A |
8: 41,361,568 (GRCm39) |
S414T |
probably benign |
Het |
| Slc9c1 |
A |
G |
16: 45,393,719 (GRCm39) |
E554G |
probably benign |
Het |
| Smad2 |
T |
C |
18: 76,433,064 (GRCm39) |
I332T |
probably damaging |
Het |
| Snrnp40 |
C |
T |
4: 130,256,451 (GRCm39) |
P59S |
probably damaging |
Het |
| Sorcs2 |
A |
T |
5: 36,222,777 (GRCm39) |
I154N |
probably damaging |
Het |
| Sort1 |
G |
A |
3: 108,255,946 (GRCm39) |
G631S |
probably damaging |
Het |
| Sox10 |
T |
C |
15: 79,043,586 (GRCm39) |
D149G |
possibly damaging |
Het |
| Spn |
C |
T |
7: 126,735,380 (GRCm39) |
V376M |
possibly damaging |
Het |
| Tacc2 |
A |
G |
7: 130,179,239 (GRCm39) |
D9G |
probably damaging |
Het |
| Tapt1 |
T |
G |
5: 44,334,448 (GRCm39) |
L514F |
possibly damaging |
Het |
| Tcf3 |
A |
G |
10: 80,249,168 (GRCm39) |
L480P |
probably damaging |
Het |
| Tenm4 |
G |
C |
7: 96,423,227 (GRCm39) |
G637A |
probably damaging |
Het |
| Tex14 |
T |
A |
11: 87,411,525 (GRCm39) |
N950K |
probably benign |
Het |
| Tgfbrap1 |
T |
G |
1: 43,098,289 (GRCm39) |
H497P |
probably benign |
Het |
| Tnfrsf18 |
A |
T |
4: 156,110,986 (GRCm39) |
Y48F |
possibly damaging |
Het |
| Tnxb |
A |
C |
17: 34,902,522 (GRCm39) |
H1002P |
probably damaging |
Het |
| Ttn |
A |
G |
2: 76,593,571 (GRCm39) |
|
probably benign |
Het |
| Ugt2b34 |
C |
G |
5: 87,041,591 (GRCm39) |
|
probably null |
Het |
| Vldlr |
A |
G |
19: 27,215,663 (GRCm39) |
D220G |
possibly damaging |
Het |
| Vmn1r33 |
A |
T |
6: 66,589,121 (GRCm39) |
Y144* |
probably null |
Het |
| Xrcc4 |
T |
C |
13: 90,140,594 (GRCm39) |
E205G |
possibly damaging |
Het |
|
| Other mutations in Patj |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00089:Patj
|
APN |
4 |
98,353,343 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00095:Patj
|
APN |
4 |
98,423,799 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
IGL00517:Patj
|
APN |
4 |
98,329,308 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL00802:Patj
|
APN |
4 |
98,312,643 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL01064:Patj
|
APN |
4 |
98,385,210 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL01110:Patj
|
APN |
4 |
98,301,261 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01407:Patj
|
APN |
4 |
98,301,287 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
IGL01821:Patj
|
APN |
4 |
98,344,448 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02399:Patj
|
APN |
4 |
98,480,173 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02494:Patj
|
APN |
4 |
98,592,224 (GRCm39) |
splice site |
probably benign |
|
|
IGL02803:Patj
|
APN |
4 |
98,314,301 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02931:Patj
|
APN |
4 |
98,299,410 (GRCm39) |
splice site |
probably benign |
|
|
IGL03017:Patj
|
APN |
4 |
98,353,264 (GRCm39) |
splice site |
probably benign |
|
|
IGL03115:Patj
|
APN |
4 |
98,332,040 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03209:Patj
|
APN |
4 |
98,353,377 (GRCm39) |
missense |
probably null |
1.00 |
|
IGL03377:Patj
|
APN |
4 |
98,353,341 (GRCm39) |
missense |
probably damaging |
1.00 |
|
D4186:Patj
|
UTSW |
4 |
98,526,999 (GRCm39) |
missense |
probably benign |
0.17 |
|
PIT4531001:Patj
|
UTSW |
4 |
98,329,327 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0136:Patj
|
UTSW |
4 |
98,555,885 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0294:Patj
|
UTSW |
4 |
98,385,285 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0376:Patj
|
UTSW |
4 |
98,457,224 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0463:Patj
|
UTSW |
4 |
98,562,545 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0465:Patj
|
UTSW |
4 |
98,423,744 (GRCm39) |
splice site |
probably null |
|
|
R0466:Patj
|
UTSW |
4 |
98,576,393 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0544:Patj
|
UTSW |
4 |
98,457,347 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0657:Patj
|
UTSW |
4 |
98,555,885 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1281:Patj
|
UTSW |
4 |
98,304,932 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1393:Patj
|
UTSW |
4 |
98,312,648 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1480:Patj
|
UTSW |
4 |
98,357,819 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1667:Patj
|
UTSW |
4 |
98,301,264 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1728:Patj
|
UTSW |
4 |
98,320,017 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R1729:Patj
|
UTSW |
4 |
98,320,017 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R1797:Patj
|
UTSW |
4 |
98,575,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1818:Patj
|
UTSW |
4 |
98,511,885 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R1835:Patj
|
UTSW |
4 |
98,379,827 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1880:Patj
|
UTSW |
4 |
98,385,477 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2009:Patj
|
UTSW |
4 |
98,344,406 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2090:Patj
|
UTSW |
4 |
98,325,560 (GRCm39) |
unclassified |
probably benign |
|
|
R2120:Patj
|
UTSW |
4 |
98,344,462 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2180:Patj
|
UTSW |
4 |
98,411,739 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2655:Patj
|
UTSW |
4 |
98,325,687 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R3156:Patj
|
UTSW |
4 |
98,562,465 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3749:Patj
|
UTSW |
4 |
98,357,837 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3767:Patj
|
UTSW |
4 |
98,569,456 (GRCm39) |
nonsense |
probably null |
|
|
R3913:Patj
|
UTSW |
4 |
98,457,338 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3917:Patj
|
UTSW |
4 |
98,480,245 (GRCm39) |
nonsense |
probably null |
|
|
R3918:Patj
|
UTSW |
4 |
98,344,455 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4299:Patj
|
UTSW |
4 |
98,565,558 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R4355:Patj
|
UTSW |
4 |
98,538,691 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R4471:Patj
|
UTSW |
4 |
98,423,816 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4762:Patj
|
UTSW |
4 |
98,293,807 (GRCm39) |
nonsense |
probably null |
|
|
R4877:Patj
|
UTSW |
4 |
98,457,295 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4945:Patj
|
UTSW |
4 |
98,383,301 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5274:Patj
|
UTSW |
4 |
98,407,218 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5343:Patj
|
UTSW |
4 |
98,564,430 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5554:Patj
|
UTSW |
4 |
98,342,633 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R5688:Patj
|
UTSW |
4 |
98,409,047 (GRCm39) |
nonsense |
probably null |
|
|
R5880:Patj
|
UTSW |
4 |
98,299,382 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5972:Patj
|
UTSW |
4 |
98,457,290 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6149:Patj
|
UTSW |
4 |
98,312,562 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R6192:Patj
|
UTSW |
4 |
98,344,394 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6265:Patj
|
UTSW |
4 |
98,357,804 (GRCm39) |
missense |
probably benign |
0.08 |
|
R6350:Patj
|
UTSW |
4 |
98,293,855 (GRCm39) |
missense |
probably benign |
0.26 |
|
R6363:Patj
|
UTSW |
4 |
98,320,097 (GRCm39) |
missense |
probably benign |
0.25 |
|
R6434:Patj
|
UTSW |
4 |
98,379,866 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6496:Patj
|
UTSW |
4 |
98,304,989 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6896:Patj
|
UTSW |
4 |
98,314,287 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7039:Patj
|
UTSW |
4 |
98,457,315 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7040:Patj
|
UTSW |
4 |
98,329,317 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7052:Patj
|
UTSW |
4 |
98,565,497 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7066:Patj
|
UTSW |
4 |
98,301,434 (GRCm39) |
missense |
probably benign |
0.24 |
|
R7236:Patj
|
UTSW |
4 |
98,299,294 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7242:Patj
|
UTSW |
4 |
98,480,170 (GRCm39) |
missense |
probably benign |
0.26 |
|
R7260:Patj
|
UTSW |
4 |
98,304,970 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7412:Patj
|
UTSW |
4 |
98,299,376 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7493:Patj
|
UTSW |
4 |
98,383,298 (GRCm39) |
missense |
probably benign |
0.41 |
|
R7570:Patj
|
UTSW |
4 |
98,312,737 (GRCm39) |
splice site |
probably null |
|
|
R7571:Patj
|
UTSW |
4 |
98,457,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7626:Patj
|
UTSW |
4 |
98,435,224 (GRCm39) |
missense |
probably benign |
0.35 |
|
R7658:Patj
|
UTSW |
4 |
98,576,416 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7664:Patj
|
UTSW |
4 |
98,385,187 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7669:Patj
|
UTSW |
4 |
98,407,179 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7796:Patj
|
UTSW |
4 |
98,435,220 (GRCm39) |
start codon destroyed |
probably benign |
0.05 |
|
R7870:Patj
|
UTSW |
4 |
98,312,553 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7883:Patj
|
UTSW |
4 |
98,499,372 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7948:Patj
|
UTSW |
4 |
98,312,547 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8050:Patj
|
UTSW |
4 |
98,427,201 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8183:Patj
|
UTSW |
4 |
98,562,466 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8239:Patj
|
UTSW |
4 |
98,570,308 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8483:Patj
|
UTSW |
4 |
98,312,539 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8546:Patj
|
UTSW |
4 |
98,325,634 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8746:Patj
|
UTSW |
4 |
98,394,067 (GRCm39) |
intron |
probably benign |
|
|
R8844:Patj
|
UTSW |
4 |
98,480,206 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8905:Patj
|
UTSW |
4 |
98,385,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8912:Patj
|
UTSW |
4 |
98,385,565 (GRCm39) |
missense |
|
|
|
R8959:Patj
|
UTSW |
4 |
98,480,212 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9083:Patj
|
UTSW |
4 |
98,401,871 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9173:Patj
|
UTSW |
4 |
98,526,958 (GRCm39) |
missense |
probably benign |
|
|
R9206:Patj
|
UTSW |
4 |
98,427,310 (GRCm39) |
missense |
unknown |
|
|
R9208:Patj
|
UTSW |
4 |
98,427,310 (GRCm39) |
missense |
unknown |
|
|
R9347:Patj
|
UTSW |
4 |
98,576,484 (GRCm39) |
missense |
probably benign |
0.19 |
|
R9560:Patj
|
UTSW |
4 |
98,570,289 (GRCm39) |
missense |
probably benign |
0.29 |
|
R9609:Patj
|
UTSW |
4 |
98,576,473 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9617:Patj
|
UTSW |
4 |
98,393,991 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9658:Patj
|
UTSW |
4 |
98,353,377 (GRCm39) |
missense |
probably null |
1.00 |
|
R9756:Patj
|
UTSW |
4 |
98,565,535 (GRCm39) |
missense |
probably benign |
|
|
Z1176:Patj
|
UTSW |
4 |
98,564,555 (GRCm39) |
nonsense |
probably null |
|
|
Z1176:Patj
|
UTSW |
4 |
98,499,367 (GRCm39) |
missense |
probably benign |
0.11 |
|
Z1177:Patj
|
UTSW |
4 |
98,385,411 (GRCm39) |
missense |
probably benign |
0.01 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCACATAAGTGACCACAGTGTCTCC -3'
(R):5'- CCTGCTTCCTCTTGAAATAGGCCAC -3'
Sequencing Primer
(F):5'- CTTTTCAGGGGGATCAGCAC -3'
(R):5'- tttccttccttccttccttcc -3'
|
| Posted On |
2013-07-11 |
Incidental Mutation