Incidental Mutation 'R7599:Adamts3'
| ID |
587893 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Adamts3
|
| Ensembl Gene |
ENSMUSG00000043635 |
| Gene Name |
ADAM metallopeptidase with thrombospondin type 1 motif 3 |
| Synonyms |
1100001H14Rik, 6330442E02Rik |
| MMRRC Submission |
045673-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R7599 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
5 |
| Chromosomal Location |
89824946-90031193 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 90009256 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Glycine
at position 136
(S136G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000132219
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000061427]
[ENSMUST00000163159]
[ENSMUST00000198151]
|
| AlphaFold |
E9Q287 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000061427
AA Change: S136G
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000058552
Gene: ENSMUSG00000043635
AA Change: S136G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
Pfam:Pep_M12B_propep
|
42 |
201 |
5.1e-40 |
PFAM |
|
Pfam:Reprolysin_5
|
254 |
439 |
5.4e-15 |
PFAM |
|
Pfam:Reprolysin_4
|
256 |
454 |
1.9e-10 |
PFAM |
|
Pfam:Reprolysin
|
257 |
460 |
3.6e-22 |
PFAM |
|
Pfam:Reprolysin_2
|
274 |
451 |
7.7e-13 |
PFAM |
|
Pfam:Reprolysin_3
|
278 |
409 |
1.5e-12 |
PFAM |
|
TSP1
|
554 |
606 |
1.26e-15 |
SMART |
|
Pfam:ADAM_spacer1
|
713 |
827 |
3e-34 |
PFAM |
|
TSP1
|
848 |
905 |
4.35e-2 |
SMART |
|
TSP1
|
908 |
967 |
4.95e-2 |
SMART |
|
TSP1
|
969 |
1016 |
6.58e-5 |
SMART |
|
low complexity region
|
1114 |
1128 |
N/A |
INTRINSIC |
|
low complexity region
|
1157 |
1177 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000163159
AA Change: S136G
PolyPhen 2
Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
|
| SMART Domains |
Protein: ENSMUSP00000132219
Gene: ENSMUSG00000043635
AA Change: S136G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
Pfam:Pep_M12B_propep
|
43 |
201 |
1.5e-40 |
PFAM |
|
Pfam:Reprolysin_5
|
254 |
439 |
2.2e-15 |
PFAM |
|
Pfam:Reprolysin_4
|
256 |
454 |
7.7e-11 |
PFAM |
|
Pfam:Reprolysin
|
257 |
460 |
3.7e-21 |
PFAM |
|
Pfam:Reprolysin_2
|
274 |
451 |
4.3e-14 |
PFAM |
|
Pfam:Reprolysin_3
|
278 |
409 |
1.3e-12 |
PFAM |
|
TSP1
|
554 |
606 |
1.26e-15 |
SMART |
|
Pfam:ADAM_spacer1
|
713 |
828 |
3.6e-28 |
PFAM |
|
TSP1
|
849 |
906 |
4.35e-2 |
SMART |
|
TSP1
|
909 |
968 |
4.95e-2 |
SMART |
|
TSP1
|
970 |
1017 |
6.58e-5 |
SMART |
|
low complexity region
|
1115 |
1129 |
N/A |
INTRINSIC |
|
low complexity region
|
1158 |
1178 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000198151
AA Change: S136G
PolyPhen 2
Score 0.016 (Sensitivity: 0.95; Specificity: 0.79)
|
| SMART Domains |
Protein: ENSMUSP00000142771
Gene: ENSMUSG00000043635
AA Change: S136G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
Pfam:Pep_M12B_propep
|
42 |
174 |
2.3e-29 |
PFAM |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease, a member of the procollagen aminopropeptidase subfamily of proteins, may play a role in the processing of type II fibrillar collagen in articular cartilage. [provided by RefSeq, Feb 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 71 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Apba3 |
T |
A |
10: 81,108,180 (GRCm39) |
N445K |
probably damaging |
Het |
| Aqp6 |
A |
G |
15: 99,501,652 (GRCm39) |
K237E |
possibly damaging |
Het |
| Arhgap23 |
A |
G |
11: 97,391,169 (GRCm39) |
T1229A |
probably benign |
Het |
| Bpifb1 |
T |
C |
2: 154,056,071 (GRCm39) |
I379T |
probably damaging |
Het |
| Bpnt2 |
G |
A |
4: 4,778,207 (GRCm39) |
T177I |
probably damaging |
Het |
| Ccdc169 |
A |
G |
3: 55,047,530 (GRCm39) |
D7G |
probably damaging |
Het |
| Cyp2f2 |
T |
A |
7: 26,830,784 (GRCm39) |
|
probably null |
Het |
| Daam2 |
T |
A |
17: 49,787,755 (GRCm39) |
K453* |
probably null |
Het |
| Dennd4c |
T |
C |
4: 86,729,849 (GRCm39) |
L817P |
probably damaging |
Het |
| Efcab6 |
T |
A |
15: 83,755,189 (GRCm39) |
R1376W |
probably damaging |
Het |
| Esrra |
G |
T |
19: 6,891,214 (GRCm39) |
A182E |
possibly damaging |
Het |
| Fam234b |
T |
A |
6: 135,203,874 (GRCm39) |
V392E |
probably damaging |
Het |
| Fanca |
A |
G |
8: 123,997,999 (GRCm39) |
V1229A |
probably benign |
Het |
| Fdps |
G |
T |
3: 89,006,693 (GRCm39) |
Q66K |
probably benign |
Het |
| Fer1l6 |
T |
A |
15: 58,499,438 (GRCm39) |
D1269E |
probably benign |
Het |
| Foxred1 |
G |
A |
9: 35,116,932 (GRCm39) |
R353W |
probably damaging |
Het |
| Gabrg2 |
C |
T |
11: 41,858,451 (GRCm39) |
V226I |
possibly damaging |
Het |
| Gcnt2 |
C |
A |
13: 41,014,343 (GRCm39) |
C171* |
probably null |
Het |
| Glyat |
C |
A |
19: 12,617,172 (GRCm39) |
A8E |
probably damaging |
Het |
| Golgb1 |
C |
A |
16: 36,695,758 (GRCm39) |
R86S |
unknown |
Het |
| Hc |
T |
A |
2: 34,940,431 (GRCm39) |
T136S |
probably damaging |
Het |
| Hdac1 |
G |
T |
4: 129,411,259 (GRCm39) |
S421* |
probably null |
Het |
| Hmcn2 |
G |
T |
2: 31,246,298 (GRCm39) |
A756S |
possibly damaging |
Het |
| Igkv8-26 |
A |
G |
6: 70,170,571 (GRCm39) |
N54S |
probably benign |
Het |
| Itgae |
T |
A |
11: 73,012,786 (GRCm39) |
V706E |
possibly damaging |
Het |
| Itgax |
G |
A |
7: 127,747,262 (GRCm39) |
V992M |
probably damaging |
Het |
| Klk10 |
A |
G |
7: 43,433,851 (GRCm39) |
D221G |
probably benign |
Het |
| Klkb1 |
T |
C |
8: 45,731,150 (GRCm39) |
I205V |
probably benign |
Het |
| Kpna2 |
T |
C |
11: 106,889,583 (GRCm39) |
N8S |
probably null |
Het |
| L3mbtl1 |
A |
C |
2: 162,806,434 (GRCm39) |
T442P |
possibly damaging |
Het |
| Lrp1b |
C |
T |
2: 40,551,561 (GRCm39) |
C4181Y |
|
Het |
| Mcat |
T |
C |
15: 83,431,872 (GRCm39) |
Y332C |
probably damaging |
Het |
| Mecom |
T |
C |
3: 30,010,534 (GRCm39) |
D648G |
probably damaging |
Het |
| Mesp2 |
A |
T |
7: 79,460,717 (GRCm39) |
D14V |
probably damaging |
Het |
| Mlh3 |
A |
T |
12: 85,314,973 (GRCm39) |
Y404* |
probably null |
Het |
| Mterf3 |
A |
T |
13: 67,065,212 (GRCm39) |
F230I |
probably damaging |
Het |
| Nrxn3 |
T |
C |
12: 89,478,832 (GRCm39) |
V602A |
probably benign |
Het |
| Or4a74 |
T |
A |
2: 89,439,571 (GRCm39) |
I292F |
possibly damaging |
Het |
| Plekhg6 |
A |
G |
6: 125,351,623 (GRCm39) |
F209L |
probably damaging |
Het |
| Pmp22 |
C |
A |
11: 63,049,174 (GRCm39) |
A139D |
probably damaging |
Het |
| Polr2e |
T |
C |
10: 79,874,404 (GRCm39) |
D34G |
possibly damaging |
Het |
| Ppard |
T |
A |
17: 28,516,091 (GRCm39) |
L105H |
probably damaging |
Het |
| Ptpn14 |
T |
A |
1: 189,582,942 (GRCm39) |
D596E |
probably benign |
Het |
| Ptprz1 |
C |
T |
6: 23,002,518 (GRCm39) |
A1536V |
not run |
Het |
| Qng1 |
T |
A |
13: 58,529,649 (GRCm39) |
H321L |
probably damaging |
Het |
| Rabgap1 |
TGGGG |
TGGG |
2: 37,392,908 (GRCm39) |
|
probably null |
Het |
| Retreg1 |
T |
A |
15: 25,971,727 (GRCm39) |
D222E |
probably benign |
Het |
| Rmnd1 |
T |
C |
10: 4,363,404 (GRCm39) |
K282R |
probably benign |
Het |
| Rsf1 |
ATGGCG |
ATGGCGACGGTGGCG |
7: 97,229,111 (GRCm39) |
|
probably benign |
Het |
| Sall3 |
C |
T |
18: 81,015,267 (GRCm39) |
R887H |
possibly damaging |
Het |
| Samd3 |
A |
G |
10: 26,139,711 (GRCm39) |
D281G |
probably benign |
Het |
| Scube1 |
T |
A |
15: 83,497,653 (GRCm39) |
D766V |
probably damaging |
Het |
| Sec24b |
TGC |
TGCAGC |
3: 129,834,460 (GRCm39) |
|
probably benign |
Het |
| Slc2a2 |
A |
G |
3: 28,752,166 (GRCm39) |
M1V |
probably null |
Het |
| Slc39a2 |
A |
T |
14: 52,132,488 (GRCm39) |
T144S |
probably benign |
Het |
| Slc5a9 |
T |
C |
4: 111,734,937 (GRCm39) |
H619R |
probably benign |
Het |
| Slco4a1 |
T |
C |
2: 180,113,048 (GRCm39) |
F427L |
probably benign |
Het |
| Snapc3 |
C |
A |
4: 83,336,073 (GRCm39) |
Y28* |
probably null |
Het |
| St3gal6 |
C |
T |
16: 58,293,800 (GRCm39) |
R243H |
probably benign |
Het |
| Stat2 |
T |
A |
10: 128,113,066 (GRCm39) |
N119K |
possibly damaging |
Het |
| Syne2 |
G |
C |
12: 76,013,145 (GRCm39) |
V2779L |
probably benign |
Het |
| Tacc1 |
T |
A |
8: 25,691,301 (GRCm39) |
M1L |
probably damaging |
Het |
| Tbc1d32 |
A |
T |
10: 56,027,929 (GRCm39) |
F724L |
possibly damaging |
Het |
| Ttc23l |
A |
G |
15: 10,533,766 (GRCm39) |
I259T |
possibly damaging |
Het |
| Ucn2 |
T |
C |
9: 108,815,292 (GRCm39) |
I18T |
probably benign |
Het |
| Wdr35 |
G |
C |
12: 9,074,886 (GRCm39) |
A1000P |
probably benign |
Het |
| Wnk1 |
C |
A |
6: 119,906,789 (GRCm39) |
C244F |
possibly damaging |
Het |
| Zeb2 |
T |
G |
2: 44,884,625 (GRCm39) |
D1022A |
probably damaging |
Het |
| Zfp26 |
A |
T |
9: 20,349,129 (GRCm39) |
H478Q |
probably damaging |
Het |
| Zfp410 |
A |
G |
12: 84,378,630 (GRCm39) |
K265R |
probably benign |
Het |
| Zfp575 |
T |
C |
7: 24,286,093 (GRCm39) |
D21G |
probably benign |
Het |
|
| Other mutations in Adamts3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00160:Adamts3
|
APN |
5 |
90,009,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00340:Adamts3
|
APN |
5 |
89,849,525 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00923:Adamts3
|
APN |
5 |
89,832,235 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL01420:Adamts3
|
APN |
5 |
89,850,916 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
IGL01522:Adamts3
|
APN |
5 |
89,850,802 (GRCm39) |
missense |
probably benign |
0.14 |
|
IGL01676:Adamts3
|
APN |
5 |
90,029,402 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
IGL01676:Adamts3
|
APN |
5 |
89,825,613 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01678:Adamts3
|
APN |
5 |
89,855,715 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01936:Adamts3
|
APN |
5 |
90,009,282 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01956:Adamts3
|
APN |
5 |
89,825,770 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02342:Adamts3
|
APN |
5 |
89,839,332 (GRCm39) |
splice site |
probably null |
|
|
IGL02415:Adamts3
|
APN |
5 |
89,854,506 (GRCm39) |
splice site |
probably null |
|
|
IGL03261:Adamts3
|
APN |
5 |
90,030,756 (GRCm39) |
utr 5 prime |
probably benign |
|
|
IGL03301:Adamts3
|
APN |
5 |
89,855,263 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0041:Adamts3
|
UTSW |
5 |
89,832,326 (GRCm39) |
missense |
probably benign |
|
|
R0079:Adamts3
|
UTSW |
5 |
89,840,912 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0096:Adamts3
|
UTSW |
5 |
89,849,576 (GRCm39) |
nonsense |
probably null |
|
|
R0096:Adamts3
|
UTSW |
5 |
89,849,576 (GRCm39) |
nonsense |
probably null |
|
|
R0477:Adamts3
|
UTSW |
5 |
89,832,366 (GRCm39) |
missense |
probably benign |
|
|
R0605:Adamts3
|
UTSW |
5 |
90,009,334 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R1036:Adamts3
|
UTSW |
5 |
89,843,952 (GRCm39) |
splice site |
probably benign |
|
|
R1462:Adamts3
|
UTSW |
5 |
90,009,208 (GRCm39) |
missense |
probably benign |
0.17 |
|
R1462:Adamts3
|
UTSW |
5 |
90,009,208 (GRCm39) |
missense |
probably benign |
0.17 |
|
R1621:Adamts3
|
UTSW |
5 |
89,869,560 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1799:Adamts3
|
UTSW |
5 |
89,923,280 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2163:Adamts3
|
UTSW |
5 |
89,856,577 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2412:Adamts3
|
UTSW |
5 |
89,849,630 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2420:Adamts3
|
UTSW |
5 |
89,831,034 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R2421:Adamts3
|
UTSW |
5 |
89,831,034 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R2422:Adamts3
|
UTSW |
5 |
89,831,034 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R2921:Adamts3
|
UTSW |
5 |
90,009,393 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R2922:Adamts3
|
UTSW |
5 |
90,009,393 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R2923:Adamts3
|
UTSW |
5 |
90,009,393 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R3402:Adamts3
|
UTSW |
5 |
89,849,592 (GRCm39) |
missense |
probably benign |
0.04 |
|
R3431:Adamts3
|
UTSW |
5 |
89,855,312 (GRCm39) |
splice site |
probably benign |
|
|
R3432:Adamts3
|
UTSW |
5 |
89,855,312 (GRCm39) |
splice site |
probably benign |
|
|
R3813:Adamts3
|
UTSW |
5 |
89,825,785 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R3816:Adamts3
|
UTSW |
5 |
89,853,123 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3905:Adamts3
|
UTSW |
5 |
90,009,214 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3906:Adamts3
|
UTSW |
5 |
90,009,214 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3907:Adamts3
|
UTSW |
5 |
90,009,214 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3908:Adamts3
|
UTSW |
5 |
90,009,214 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4557:Adamts3
|
UTSW |
5 |
89,848,346 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4684:Adamts3
|
UTSW |
5 |
89,850,866 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4844:Adamts3
|
UTSW |
5 |
89,825,675 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4925:Adamts3
|
UTSW |
5 |
89,832,182 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5097:Adamts3
|
UTSW |
5 |
89,840,909 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5100:Adamts3
|
UTSW |
5 |
89,856,502 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5237:Adamts3
|
UTSW |
5 |
89,923,236 (GRCm39) |
missense |
probably benign |
|
|
R5265:Adamts3
|
UTSW |
5 |
90,009,411 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R5322:Adamts3
|
UTSW |
5 |
89,855,159 (GRCm39) |
splice site |
probably null |
|
|
R5413:Adamts3
|
UTSW |
5 |
89,856,626 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5459:Adamts3
|
UTSW |
5 |
89,839,332 (GRCm39) |
splice site |
probably null |
|
|
R5738:Adamts3
|
UTSW |
5 |
89,856,527 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5979:Adamts3
|
UTSW |
5 |
90,009,528 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5992:Adamts3
|
UTSW |
5 |
89,839,194 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6364:Adamts3
|
UTSW |
5 |
89,869,673 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6572:Adamts3
|
UTSW |
5 |
90,009,468 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7098:Adamts3
|
UTSW |
5 |
90,009,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7172:Adamts3
|
UTSW |
5 |
90,030,860 (GRCm39) |
start gained |
probably benign |
|
|
R7263:Adamts3
|
UTSW |
5 |
89,825,601 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7401:Adamts3
|
UTSW |
5 |
89,855,309 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7829:Adamts3
|
UTSW |
5 |
90,009,349 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7835:Adamts3
|
UTSW |
5 |
89,848,299 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R7892:Adamts3
|
UTSW |
5 |
90,009,288 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8021:Adamts3
|
UTSW |
5 |
89,831,043 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R8289:Adamts3
|
UTSW |
5 |
89,923,282 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8350:Adamts3
|
UTSW |
5 |
89,850,815 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8468:Adamts3
|
UTSW |
5 |
89,842,627 (GRCm39) |
missense |
probably benign |
0.19 |
|
R8827:Adamts3
|
UTSW |
5 |
89,839,324 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8864:Adamts3
|
UTSW |
5 |
89,854,981 (GRCm39) |
intron |
probably benign |
|
|
R8906:Adamts3
|
UTSW |
5 |
89,825,575 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9000:Adamts3
|
UTSW |
5 |
89,854,570 (GRCm39) |
missense |
probably benign |
0.17 |
|
R9005:Adamts3
|
UTSW |
5 |
89,825,693 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9378:Adamts3
|
UTSW |
5 |
89,848,269 (GRCm39) |
nonsense |
probably null |
|
|
R9505:Adamts3
|
UTSW |
5 |
89,855,751 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9516:Adamts3
|
UTSW |
5 |
89,834,750 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0064:Adamts3
|
UTSW |
5 |
89,850,901 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
Z1088:Adamts3
|
UTSW |
5 |
89,832,308 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1176:Adamts3
|
UTSW |
5 |
89,923,210 (GRCm39) |
missense |
not run |
|
|
Z1177:Adamts3
|
UTSW |
5 |
89,923,210 (GRCm39) |
missense |
not run |
|
|
Z1177:Adamts3
|
UTSW |
5 |
89,855,723 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CTGCCAAACCCACTATGCTG -3'
(R):5'- AGAGCATTTGTTCTTCAACGTCAC -3'
Sequencing Primer
(F):5'- AACCCACTATGCTGCCTATAGTTGAG -3'
(R):5'- TTCAACGTCACGGCATTTGGAAG -3'
|
| Posted On |
2019-10-24 |
Incidental Mutation