Mutagenetix > Incidental Mutation

Incidental Mutation 'R7603:Csmd1'

588117

Institutional Source

Beutler Lab

Gene Symbol

Csmd1

Ensembl Gene

ENSMUSG00000060924

Gene Name

CUB and Sushi multiple domains 1

Synonyms

MMRRC Submission

045713-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R7603 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

15892537-17535586 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 16288682 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Glutamic Acid at position 470 (D470E)

Ref Sequence

ENSEMBL: ENSMUSP00000080751 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000082104]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000082104
AA Change: D470E

PolyPhen 2 Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)

SMART Domains

Protein: ENSMUSP00000080751
Gene: ENSMUSG00000060924
AA Change: D470E

Domain	Start	End	E-Value	Type
signal peptide	1	29	N/A	INTRINSIC
CUB	32	140	1.46e-26	SMART
CCP	145	202	1.01e-11	SMART
CUB	208	312	1.05e-27	SMART
CCP	349	406	1.28e-8	SMART
CUB	411	522	2.34e-25	SMART
CCP	527	580	1.22e-14	SMART
CUB	584	692	1.61e-37	SMART
CCP	697	754	4.41e-12	SMART
CUB	758	866	6.55e-38	SMART
CCP	873	926	2.53e-12	SMART
CUB	930	1040	8.94e-22	SMART
CCP	1045	1100	7.06e-11	SMART
CUB	1104	1212	3.14e-26	SMART
CCP	1217	1273	1.18e-12	SMART
CUB	1277	1386	9.72e-32	SMART
CCP	1391	1447	2.06e-12	SMART
CUB	1451	1559	1.68e-35	SMART
CCP	1564	1621	2.53e-12	SMART
CUB	1625	1733	4.24e-14	SMART
CCP	1741	1798	9.46e-12	SMART
CUB	1802	1910	4.23e-32	SMART
CCP	1915	1970	8.23e-12	SMART
CUB	1974	2082	8.59e-33	SMART
CCP	2087	2142	6.09e-15	SMART
CUB	2146	2253	2.36e-30	SMART
CCP	2258	2315	1.1e-12	SMART
CUB	2320	2430	4.3e-24	SMART
CCP	2432	2490	2.94e-8	SMART
CCP	2495	2552	2.03e-11	SMART
CCP	2557	2617	1.22e-5	SMART
CCP	2622	2675	2.72e-12	SMART
CCP	2680	2733	5.86e-17	SMART
CCP	2738	2791	6.09e-15	SMART
CCP	2796	2854	9.1e-14	SMART
CCP	2859	2912	3.96e-14	SMART
CCP	2920	2973	4.41e-12	SMART
CCP	2978	3032	2.94e-8	SMART
CCP	3037	3092	6.59e-11	SMART
CCP	3097	3150	4.12e-12	SMART
CCP	3155	3208	7.92e-14	SMART
CCP	3216	3270	2.8e-14	SMART
CCP	3275	3330	3.78e-11	SMART
transmembrane domain	3487	3509	N/A	INTRINSIC

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.7%
20x: 98.9%

Validation Efficiency

98% (47/48)

MGI Phenotype

PHENOTYPE: Mice exhibit normal pre-pulse inhibition, social interaction, sucrose preference and d-amphetamine sensitivity. [provided by MGI curators]

Allele List at MGI

All alleles(1) : Targeted, knock-out(1)

Other mutations in this stock

Total: 47 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
0610010F05Rik	T	C	11: 23,566,191 (GRCm38)	T709A	probably benign	Het
Abca6	T	C	11: 110,180,258 (GRCm38)	K1536E	possibly damaging	Het
Abhd16a	T	A	17: 35,101,960 (GRCm38)		probably null	Het
Actrt3	C	T	3: 30,598,547 (GRCm38)	A133T	probably benign	Het
Adcy10	C	T	1: 165,564,237 (GRCm38)	R1329W	probably damaging	Het
Apol7b	T	C	15: 77,423,456 (GRCm38)	M280V	possibly damaging	Het
Canx	A	T	11: 50,311,628 (GRCm38)	D50E	probably benign	Het
Cyp2c23	C	T	19: 44,014,930 (GRCm38)	D269N	probably damaging	Het
Ddah1	T	C	3: 145,759,019 (GRCm38)	V53A	probably benign	Het
Epha7	C	T	4: 28,871,937 (GRCm38)	S422L	probably benign	Het
Fastkd5	A	G	2: 130,615,041 (GRCm38)	V543A	possibly damaging	Het
Fggy	G	A	4: 95,769,506 (GRCm38)	G295R	probably damaging	Het
Frs2	T	C	10: 117,074,063 (GRCm38)	T465A	probably benign	Het
Glipr1	A	T	10: 111,988,832 (GRCm38)	N156K	probably benign	Het
Gnpnat1	C	T	14: 45,384,617 (GRCm38)	V40I	probably benign	Het
H2-Q7	T	C	17: 35,439,963 (GRCm38)	L130P	probably damaging	Het
Herc1	T	A	9: 66,451,383 (GRCm38)	L86*	probably null	Het
Hspg2	T	C	4: 137,548,368 (GRCm38)	L2778P	probably damaging	Het
Hspg2	T	A	4: 137,557,192 (GRCm38)	I3487N	possibly damaging	Het
Htra4	T	G	8: 25,025,700 (GRCm38)	I441L	probably benign	Het
Ints7	A	T	1: 191,596,224 (GRCm38)	H203L	probably damaging	Het
Lama2	T	C	10: 27,266,680 (GRCm38)	T601A	possibly damaging	Het
Lin7b	T	C	7: 45,368,432 (GRCm38)		probably benign	Het
Lmbr1l	G	A	15: 98,908,691 (GRCm38)	Q280*	probably null	Het
Lpin3	G	T	2: 160,903,754 (GRCm38)		probably null	Het
Map1lc3b	A	T	8: 121,593,529 (GRCm38)	H27L	possibly damaging	Het
Mfsd14a	C	A	3: 116,633,883 (GRCm38)	V369F	probably damaging	Het
Ndufa12	C	T	10: 94,220,779 (GRCm38)	A123V	probably benign	Het
Nek9	A	G	12: 85,303,514 (GRCm38)	F929L	probably benign	Het
Nup210	A	T	6: 91,076,697 (GRCm38)	D279E	probably benign	Het
Olfr553	A	G	7: 102,614,938 (GRCm38)	V17A	probably benign	Het
Parp1	T	C	1: 180,600,212 (GRCm38)		probably null	Het
Phc3	T	C	3: 30,907,452 (GRCm38)	I944V	probably damaging	Het
Phf20	C	T	2: 156,302,851 (GRCm38)	A793V	probably benign	Het
Phf21a	A	C	2: 92,357,007 (GRCm38)	R540S	probably benign	Het
Pogk	A	G	1: 166,401,911 (GRCm38)	C124R	probably benign	Het
Rif1	C	T	2: 52,076,175 (GRCm38)	S93L	probably damaging	Het
Sele	A	G	1: 164,049,515 (GRCm38)	E120G	probably damaging	Het
Slc4a1ap	T	C	5: 31,546,195 (GRCm38)	L49P		Het
Snap47	T	C	11: 59,428,547 (GRCm38)	D255G	probably damaging	Het
Tcstv3	T	C	13: 120,317,610 (GRCm38)	V15A	probably damaging	Het
Tmcc1	A	T	6: 116,043,131 (GRCm38)	Y453*	probably null	Het
Tpsg1	G	T	17: 25,373,210 (GRCm38)	G86V	probably damaging	Het
Urb1	CACTTAC	CAC	16: 90,772,573 (GRCm38)		probably benign	Het
Usp20	T	A	2: 31,011,474 (GRCm38)	V459E	probably damaging	Het
Vmn1r202	A	T	13: 22,501,620 (GRCm38)	L209Q	probably damaging	Het
Vps13b	T	C	15: 35,576,439 (GRCm38)	S998P	probably damaging	Het

Other mutations in Csmd1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00095:Csmd1	APN	8	16,009,297 (GRCm38)	splice site	probably benign
IGL00433:Csmd1	APN	8	16,231,373 (GRCm38)	missense	probably damaging	1.00
IGL00500:Csmd1	APN	8	15,921,139 (GRCm38)	missense	probably damaging	1.00
IGL00666:Csmd1	APN	8	16,189,990 (GRCm38)	missense	probably damaging	1.00
IGL00913:Csmd1	APN	8	16,071,287 (GRCm38)	missense	probably benign	0.00
IGL01012:Csmd1	APN	8	15,917,341 (GRCm38)	missense	probably benign	0.00
IGL01123:Csmd1	APN	8	17,534,928 (GRCm38)	missense	possibly damaging	0.96
IGL01348:Csmd1	APN	8	15,910,596 (GRCm38)	missense	probably damaging	0.99
IGL01444:Csmd1	APN	8	16,200,055 (GRCm38)	missense	probably benign	0.00
IGL01530:Csmd1	APN	8	15,903,195 (GRCm38)	missense	probably damaging	0.99
IGL01548:Csmd1	APN	8	16,288,646 (GRCm38)	nonsense	probably null
IGL01814:Csmd1	APN	8	16,501,375 (GRCm38)	missense	probably damaging	1.00
IGL01889:Csmd1	APN	8	15,998,857 (GRCm38)	missense	probably damaging	1.00
IGL02055:Csmd1	APN	8	16,069,001 (GRCm38)	missense	probably damaging	0.99
IGL02066:Csmd1	APN	8	15,926,594 (GRCm38)	missense	probably damaging	1.00
IGL02097:Csmd1	APN	8	16,211,759 (GRCm38)	missense	probably null	0.17
IGL02112:Csmd1	APN	8	16,081,705 (GRCm38)	missense	probably benign	0.18
IGL02161:Csmd1	APN	8	16,358,412 (GRCm38)	missense	probably damaging	0.97
IGL02189:Csmd1	APN	8	16,271,606 (GRCm38)	missense	probably damaging	0.99
IGL02272:Csmd1	APN	8	16,199,893 (GRCm38)	missense	probably damaging	0.99
IGL02292:Csmd1	APN	8	16,211,870 (GRCm38)	missense	probably damaging	1.00
IGL02385:Csmd1	APN	8	15,903,275 (GRCm38)	missense	probably benign	0.08
IGL02424:Csmd1	APN	8	16,092,326 (GRCm38)	missense	probably benign	0.22
IGL02492:Csmd1	APN	8	16,002,597 (GRCm38)	missense	probably benign	0.13
IGL02507:Csmd1	APN	8	17,534,976 (GRCm38)	utr 5 prime	probably benign
IGL02513:Csmd1	APN	8	15,999,869 (GRCm38)	splice site	probably benign
IGL02727:Csmd1	APN	8	16,231,327 (GRCm38)	missense	probably damaging	1.00
IGL02728:Csmd1	APN	8	15,999,779 (GRCm38)	critical splice donor site	probably null
IGL02852:Csmd1	APN	8	15,895,728 (GRCm38)	missense	probably damaging	0.99
IGL02935:Csmd1	APN	8	16,223,334 (GRCm38)	missense	probably damaging	1.00
IGL02945:Csmd1	APN	8	16,271,570 (GRCm38)	missense	possibly damaging	0.92
IGL02959:Csmd1	APN	8	15,910,465 (GRCm38)	missense	probably damaging	0.99
IGL03113:Csmd1	APN	8	16,028,698 (GRCm38)	missense	probably benign
IGL03129:Csmd1	APN	8	15,961,521 (GRCm38)	missense	probably damaging	0.99
IGL03131:Csmd1	APN	8	16,088,217 (GRCm38)	missense	probably damaging	1.00
IGL03275:Csmd1	APN	8	16,157,092 (GRCm38)	missense	probably benign	0.00
IGL03297:Csmd1	APN	8	16,009,432 (GRCm38)	nonsense	probably null
ikura	UTSW	8	16,231,271 (GRCm38)	missense	probably damaging	1.00
I2289:Csmd1	UTSW	8	15,912,381 (GRCm38)	missense	probably benign	0.10
IGL03055:Csmd1	UTSW	8	16,095,501 (GRCm38)	missense	probably damaging	1.00
IGL03097:Csmd1	UTSW	8	15,945,127 (GRCm38)	missense	probably damaging	1.00
PIT4260001:Csmd1	UTSW	8	16,070,313 (GRCm38)	missense	probably damaging	1.00
PIT4378001:Csmd1	UTSW	8	15,895,728 (GRCm38)	missense	probably damaging	0.99
PIT4520001:Csmd1	UTSW	8	15,906,023 (GRCm38)	missense	probably benign	0.01
R0037:Csmd1	UTSW	8	15,917,248 (GRCm38)	missense	probably damaging	0.97
R0095:Csmd1	UTSW	8	16,233,051 (GRCm38)	missense	probably damaging	1.00
R0113:Csmd1	UTSW	8	15,984,849 (GRCm38)	missense	probably damaging	1.00
R0129:Csmd1	UTSW	8	16,079,942 (GRCm38)	missense	possibly damaging	0.95
R0144:Csmd1	UTSW	8	16,391,824 (GRCm38)	missense	probably benign	0.16
R0166:Csmd1	UTSW	8	16,233,022 (GRCm38)	missense	probably benign	0.29
R0227:Csmd1	UTSW	8	16,391,822 (GRCm38)	missense	probably benign	0.05
R0279:Csmd1	UTSW	8	16,223,235 (GRCm38)	missense	probably damaging	0.99
R0280:Csmd1	UTSW	8	16,271,602 (GRCm38)	missense	probably damaging	1.00
R0312:Csmd1	UTSW	8	15,984,760 (GRCm38)	missense	probably damaging	1.00
R0355:Csmd1	UTSW	8	15,918,330 (GRCm38)	missense	probably damaging	0.97
R0367:Csmd1	UTSW	8	15,917,270 (GRCm38)	missense	probably damaging	1.00
R0395:Csmd1	UTSW	8	16,346,638 (GRCm38)	missense	probably damaging	0.99
R0413:Csmd1	UTSW	8	16,710,514 (GRCm38)	missense	probably damaging	0.97
R0457:Csmd1	UTSW	8	16,501,393 (GRCm38)	critical splice acceptor site	probably null
R0463:Csmd1	UTSW	8	15,921,759 (GRCm38)	missense	probably damaging	0.99
R0482:Csmd1	UTSW	8	16,233,101 (GRCm38)	missense	probably damaging	1.00
R0501:Csmd1	UTSW	8	17,027,323 (GRCm38)	missense	probably damaging	0.97
R0505:Csmd1	UTSW	8	15,992,758 (GRCm38)	missense	probably damaging	1.00
R0507:Csmd1	UTSW	8	16,185,344 (GRCm38)	splice site	probably benign
R0511:Csmd1	UTSW	8	15,932,529 (GRCm38)	missense	possibly damaging	0.80
R0555:Csmd1	UTSW	8	16,185,273 (GRCm38)	missense	probably benign
R0580:Csmd1	UTSW	8	15,910,528 (GRCm38)	missense	probably damaging	1.00
R0610:Csmd1	UTSW	8	15,918,208 (GRCm38)	missense	possibly damaging	0.95
R0634:Csmd1	UTSW	8	16,226,391 (GRCm38)	missense	probably damaging	1.00
R0666:Csmd1	UTSW	8	16,069,049 (GRCm38)	missense	possibly damaging	0.88
R0674:Csmd1	UTSW	8	16,000,550 (GRCm38)	missense	probably benign	0.03
R0675:Csmd1	UTSW	8	16,158,131 (GRCm38)	missense	probably benign	0.01
R0763:Csmd1	UTSW	8	17,027,284 (GRCm38)	missense	possibly damaging	0.67
R0781:Csmd1	UTSW	8	15,921,174 (GRCm38)	missense	probably benign	0.35
R0862:Csmd1	UTSW	8	16,190,026 (GRCm38)	missense	probably damaging	0.99
R0864:Csmd1	UTSW	8	16,190,026 (GRCm38)	missense	probably damaging	0.99
R0925:Csmd1	UTSW	8	16,710,618 (GRCm38)	missense	probably benign	0.29
R0926:Csmd1	UTSW	8	16,033,576 (GRCm38)	splice site	probably null
R1005:Csmd1	UTSW	8	16,288,693 (GRCm38)	missense	probably damaging	0.99
R1073:Csmd1	UTSW	8	16,358,463 (GRCm38)	splice site	probably benign
R1185:Csmd1	UTSW	8	16,358,348 (GRCm38)	missense	probably damaging	0.96
R1185:Csmd1	UTSW	8	16,358,348 (GRCm38)	missense	probably damaging	0.96
R1185:Csmd1	UTSW	8	16,358,348 (GRCm38)	missense	probably damaging	0.96
R1256:Csmd1	UTSW	8	16,079,964 (GRCm38)	missense	probably damaging	1.00
R1294:Csmd1	UTSW	8	16,698,036 (GRCm38)	missense	probably damaging	0.99
R1375:Csmd1	UTSW	8	16,463,081 (GRCm38)	splice site	probably null
R1447:Csmd1	UTSW	8	15,925,306 (GRCm38)	nonsense	probably null
R1450:Csmd1	UTSW	8	15,945,180 (GRCm38)	critical splice acceptor site	probably null
R1470:Csmd1	UTSW	8	16,157,204 (GRCm38)	splice site	probably benign
R1580:Csmd1	UTSW	8	15,925,299 (GRCm38)	missense	probably damaging	1.00
R1591:Csmd1	UTSW	8	15,900,710 (GRCm38)	missense	probably damaging	0.99
R1658:Csmd1	UTSW	8	16,081,725 (GRCm38)	missense	possibly damaging	0.69
R1678:Csmd1	UTSW	8	15,918,252 (GRCm38)	missense	possibly damaging	0.58
R1717:Csmd1	UTSW	8	17,216,692 (GRCm38)	missense	possibly damaging	0.58
R1735:Csmd1	UTSW	8	15,932,610 (GRCm38)	missense	probably damaging	0.99
R1750:Csmd1	UTSW	8	15,917,303 (GRCm38)	missense	probably damaging	0.99
R1753:Csmd1	UTSW	8	16,157,120 (GRCm38)	nonsense	probably null
R1822:Csmd1	UTSW	8	16,223,326 (GRCm38)	missense	probably damaging	1.00
R1875:Csmd1	UTSW	8	15,929,101 (GRCm38)	missense	probably damaging	0.99
R1909:Csmd1	UTSW	8	15,906,116 (GRCm38)	missense	probably damaging	1.00
R1912:Csmd1	UTSW	8	16,233,998 (GRCm38)	critical splice donor site	probably null
R1993:Csmd1	UTSW	8	16,346,684 (GRCm38)	missense	probably damaging	0.99
R2067:Csmd1	UTSW	8	15,900,782 (GRCm38)	missense	probably benign
R2094:Csmd1	UTSW	8	16,079,978 (GRCm38)	missense	probably damaging	0.99
R2119:Csmd1	UTSW	8	17,216,733 (GRCm38)	missense	probably damaging	0.98
R2127:Csmd1	UTSW	8	15,917,392 (GRCm38)	missense	probably damaging	1.00
R2138:Csmd1	UTSW	8	15,929,088 (GRCm38)	missense	probably damaging	0.96
R2216:Csmd1	UTSW	8	17,027,339 (GRCm38)	critical splice acceptor site	probably null
R2220:Csmd1	UTSW	8	15,992,641 (GRCm38)	missense	possibly damaging	0.94
R2380:Csmd1	UTSW	8	16,190,087 (GRCm38)	missense	probably damaging	1.00
R2471:Csmd1	UTSW	8	16,211,762 (GRCm38)	missense	probably damaging	1.00
R2984:Csmd1	UTSW	8	15,953,782 (GRCm38)	missense	probably damaging	1.00
R3001:Csmd1	UTSW	8	16,196,170 (GRCm38)	missense	probably damaging	0.98
R3002:Csmd1	UTSW	8	16,196,170 (GRCm38)	missense	probably damaging	0.98
R3003:Csmd1	UTSW	8	16,196,170 (GRCm38)	missense	probably damaging	0.98
R3103:Csmd1	UTSW	8	15,917,405 (GRCm38)	missense	probably damaging	1.00
R3104:Csmd1	UTSW	8	17,027,231 (GRCm38)	missense	probably damaging	1.00
R3620:Csmd1	UTSW	8	15,992,684 (GRCm38)	missense	probably benign	0.29
R3621:Csmd1	UTSW	8	15,992,684 (GRCm38)	missense	probably benign	0.29
R3748:Csmd1	UTSW	8	15,906,071 (GRCm38)	missense	probably damaging	0.99
R3780:Csmd1	UTSW	8	16,201,986 (GRCm38)	missense	probably damaging	1.00
R3815:Csmd1	UTSW	8	16,002,522 (GRCm38)	missense	probably damaging	1.00
R3816:Csmd1	UTSW	8	16,002,522 (GRCm38)	missense	probably damaging	1.00
R3818:Csmd1	UTSW	8	16,002,522 (GRCm38)	missense	probably damaging	1.00
R3819:Csmd1	UTSW	8	16,002,522 (GRCm38)	missense	probably damaging	1.00
R3850:Csmd1	UTSW	8	16,079,922 (GRCm38)	missense	probably benign	0.00
R3945:Csmd1	UTSW	8	15,910,619 (GRCm38)	splice site	probably null
R3980:Csmd1	UTSW	8	15,906,056 (GRCm38)	nonsense	probably null
R4061:Csmd1	UTSW	8	15,945,158 (GRCm38)	missense	probably benign	0.00
R4086:Csmd1	UTSW	8	15,992,738 (GRCm38)	missense	probably damaging	0.99
R4087:Csmd1	UTSW	8	15,992,738 (GRCm38)	missense	probably damaging	0.99
R4089:Csmd1	UTSW	8	15,992,738 (GRCm38)	missense	probably damaging	0.99
R4183:Csmd1	UTSW	8	15,910,464 (GRCm38)	missense	probably damaging	0.99
R4226:Csmd1	UTSW	8	16,000,490 (GRCm38)	missense	probably damaging	0.99
R4454:Csmd1	UTSW	8	15,945,011 (GRCm38)	missense	probably damaging	0.99
R4533:Csmd1	UTSW	8	15,931,037 (GRCm38)	splice site	probably null
R4544:Csmd1	UTSW	8	16,710,636 (GRCm38)	missense	possibly damaging	0.93
R4547:Csmd1	UTSW	8	16,391,797 (GRCm38)	missense	possibly damaging	0.48
R4612:Csmd1	UTSW	8	15,921,908 (GRCm38)	splice site	probably null
R4620:Csmd1	UTSW	8	16,002,694 (GRCm38)	critical splice acceptor site	probably null
R4627:Csmd1	UTSW	8	16,697,917 (GRCm38)	missense	probably benign	0.00
R4633:Csmd1	UTSW	8	16,002,620 (GRCm38)	missense	probably damaging	0.99
R4646:Csmd1	UTSW	8	15,932,511 (GRCm38)	missense	possibly damaging	0.87
R4648:Csmd1	UTSW	8	15,998,788 (GRCm38)	nonsense	probably null
R4668:Csmd1	UTSW	8	16,023,891 (GRCm38)	missense	possibly damaging	0.50
R4709:Csmd1	UTSW	8	16,710,506 (GRCm38)	critical splice donor site	probably null
R4709:Csmd1	UTSW	8	16,023,891 (GRCm38)	missense	possibly damaging	0.96
R4741:Csmd1	UTSW	8	15,910,447 (GRCm38)	missense	probably damaging	0.99
R4774:Csmd1	UTSW	8	16,009,369 (GRCm38)	missense	probably benign	0.11
R4793:Csmd1	UTSW	8	16,088,263 (GRCm38)	missense	probably damaging	1.00
R4829:Csmd1	UTSW	8	16,127,296 (GRCm38)	missense	probably damaging	1.00
R4888:Csmd1	UTSW	8	15,895,674 (GRCm38)	utr 3 prime	probably benign
R4896:Csmd1	UTSW	8	16,009,439 (GRCm38)	missense	probably benign	0.00
R4932:Csmd1	UTSW	8	16,023,765 (GRCm38)	missense	probably damaging	0.99
R4944:Csmd1	UTSW	8	15,998,772 (GRCm38)	missense	probably damaging	1.00
R4953:Csmd1	UTSW	8	16,199,917 (GRCm38)	missense	probably damaging	0.99
R4996:Csmd1	UTSW	8	15,910,452 (GRCm38)	missense	probably damaging	0.97
R5028:Csmd1	UTSW	8	15,989,090 (GRCm38)	missense	probably damaging	1.00
R5146:Csmd1	UTSW	8	16,196,190 (GRCm38)	missense	probably damaging	1.00
R5272:Csmd1	UTSW	8	16,199,944 (GRCm38)	missense	probably damaging	0.99
R5327:Csmd1	UTSW	8	17,216,712 (GRCm38)	missense	possibly damaging	0.94
R5399:Csmd1	UTSW	8	16,710,597 (GRCm38)	missense	probably damaging	1.00
R5411:Csmd1	UTSW	8	15,910,471 (GRCm38)	missense	probably damaging	1.00
R5462:Csmd1	UTSW	8	15,961,486 (GRCm38)	missense	probably benign	0.12
R5463:Csmd1	UTSW	8	15,984,860 (GRCm38)	missense	probably benign	0.34
R5497:Csmd1	UTSW	8	16,085,181 (GRCm38)	missense	probably benign	0.20
R5536:Csmd1	UTSW	8	16,288,660 (GRCm38)	missense	probably damaging	0.99
R5711:Csmd1	UTSW	8	15,953,703 (GRCm38)	missense	probably damaging	1.00
R5730:Csmd1	UTSW	8	16,185,192 (GRCm38)	nonsense	probably null
R5788:Csmd1	UTSW	8	16,201,966 (GRCm38)	missense	probably damaging	1.00
R5941:Csmd1	UTSW	8	15,932,471 (GRCm38)	missense	probably damaging	0.99
R5960:Csmd1	UTSW	8	16,071,416 (GRCm38)	missense	possibly damaging	0.68
R5961:Csmd1	UTSW	8	16,070,352 (GRCm38)	missense	probably damaging	0.99
R5969:Csmd1	UTSW	8	16,071,353 (GRCm38)	missense	probably benign	0.00
R5998:Csmd1	UTSW	8	15,910,443 (GRCm38)	missense	probably damaging	1.00
R6062:Csmd1	UTSW	8	16,092,305 (GRCm38)	missense	possibly damaging	0.68
R6109:Csmd1	UTSW	8	16,199,860 (GRCm38)	missense	possibly damaging	0.93
R6116:Csmd1	UTSW	8	16,211,850 (GRCm38)	missense	probably damaging	1.00
R6143:Csmd1	UTSW	8	16,088,301 (GRCm38)	missense	probably damaging	1.00
R6155:Csmd1	UTSW	8	15,903,231 (GRCm38)	missense	probably benign	0.01
R6197:Csmd1	UTSW	8	15,926,611 (GRCm38)	missense	probably benign	0.32
R6247:Csmd1	UTSW	8	16,196,235 (GRCm38)	missense	possibly damaging	0.91
R6304:Csmd1	UTSW	8	16,058,674 (GRCm38)	missense	probably damaging	1.00
R6317:Csmd1	UTSW	8	16,710,642 (GRCm38)	missense	possibly damaging	0.89
R6318:Csmd1	UTSW	8	15,903,212 (GRCm38)	missense	probably damaging	1.00
R6338:Csmd1	UTSW	8	15,932,492 (GRCm38)	missense	possibly damaging	0.75
R6369:Csmd1	UTSW	8	17,535,004 (GRCm38)	start gained	probably benign
R6447:Csmd1	UTSW	8	15,910,527 (GRCm38)	missense	probably damaging	1.00
R6454:Csmd1	UTSW	8	15,921,150 (GRCm38)	missense	probably damaging	0.99
R6494:Csmd1	UTSW	8	16,211,695 (GRCm38)	splice site	probably null
R6614:Csmd1	UTSW	8	17,216,787 (GRCm38)	missense	probably damaging	1.00
R6736:Csmd1	UTSW	8	16,002,626 (GRCm38)	missense	probably damaging	0.99
R6769:Csmd1	UTSW	8	16,071,394 (GRCm38)	missense	possibly damaging	0.80
R6771:Csmd1	UTSW	8	16,071,394 (GRCm38)	missense	possibly damaging	0.80
R6804:Csmd1	UTSW	8	16,037,246 (GRCm38)	missense	probably damaging	1.00
R6818:Csmd1	UTSW	8	16,185,327 (GRCm38)	missense	probably damaging	1.00
R6863:Csmd1	UTSW	8	17,534,913 (GRCm38)	missense	possibly damaging	0.85
R6930:Csmd1	UTSW	8	16,092,395 (GRCm38)	missense	probably damaging	0.97
R6969:Csmd1	UTSW	8	17,216,789 (GRCm38)	missense	possibly damaging	0.94
R7112:Csmd1	UTSW	8	16,101,128 (GRCm38)	missense	probably damaging	1.00
R7124:Csmd1	UTSW	8	15,903,202 (GRCm38)	missense	probably damaging	1.00
R7167:Csmd1	UTSW	8	15,926,524 (GRCm38)	missense	probably benign
R7243:Csmd1	UTSW	8	15,915,357 (GRCm38)	missense	probably damaging	1.00
R7260:Csmd1	UTSW	8	16,000,574 (GRCm38)	missense	probably damaging	1.00
R7271:Csmd1	UTSW	8	17,027,279 (GRCm38)	missense	probably damaging	0.99
R7324:Csmd1	UTSW	8	16,058,707 (GRCm38)	missense	probably damaging	1.00
R7325:Csmd1	UTSW	8	16,058,707 (GRCm38)	missense	probably damaging	1.00
R7327:Csmd1	UTSW	8	16,058,707 (GRCm38)	missense	probably damaging	1.00
R7373:Csmd1	UTSW	8	15,992,713 (GRCm38)	missense	probably damaging	1.00
R7406:Csmd1	UTSW	8	16,288,693 (GRCm38)	missense	probably damaging	0.99
R7427:Csmd1	UTSW	8	16,023,850 (GRCm38)	missense	possibly damaging	0.91
R7428:Csmd1	UTSW	8	16,023,850 (GRCm38)	missense	possibly damaging	0.91
R7445:Csmd1	UTSW	8	16,158,254 (GRCm38)	missense	possibly damaging	0.61
R7458:Csmd1	UTSW	8	15,953,738 (GRCm38)	missense	probably damaging	1.00
R7476:Csmd1	UTSW	8	15,895,731 (GRCm38)	missense	probably damaging	1.00
R7527:Csmd1	UTSW	8	16,211,718 (GRCm38)	missense	probably damaging	1.00
R7544:Csmd1	UTSW	8	16,092,296 (GRCm38)	missense	probably damaging	1.00
R7583:Csmd1	UTSW	8	15,998,833 (GRCm38)	missense	probably damaging	0.96
R7607:Csmd1	UTSW	8	15,918,331 (GRCm38)	missense	possibly damaging	0.94
R7642:Csmd1	UTSW	8	16,085,178 (GRCm38)	missense	probably damaging	0.99
R7669:Csmd1	UTSW	8	15,917,273 (GRCm38)	missense	probably damaging	1.00
R7720:Csmd1	UTSW	8	15,931,108 (GRCm38)	missense	probably damaging	1.00
R7728:Csmd1	UTSW	8	16,231,271 (GRCm38)	missense	probably damaging	1.00
R7738:Csmd1	UTSW	8	16,100,990 (GRCm38)	missense	probably damaging	1.00
R7745:Csmd1	UTSW	8	15,932,461 (GRCm38)	critical splice donor site	probably null
R7879:Csmd1	UTSW	8	16,391,806 (GRCm38)	missense	probably benign	0.28
R7884:Csmd1	UTSW	8	15,961,418 (GRCm38)	missense	probably damaging	1.00
R7897:Csmd1	UTSW	8	17,534,919 (GRCm38)	missense	possibly damaging	0.96
R8111:Csmd1	UTSW	8	15,917,306 (GRCm38)	missense	probably benign
R8119:Csmd1	UTSW	8	17,027,294 (GRCm38)	missense	probably damaging	0.99
R8134:Csmd1	UTSW	8	15,932,550 (GRCm38)	missense	probably damaging	0.99
R8187:Csmd1	UTSW	8	16,127,174 (GRCm38)	missense	probably damaging	0.99
R8196:Csmd1	UTSW	8	16,009,468 (GRCm38)	missense	probably benign	0.18
R8231:Csmd1	UTSW	8	16,697,923 (GRCm38)	missense	possibly damaging	0.82
R8242:Csmd1	UTSW	8	16,710,654 (GRCm38)	missense	probably benign	0.42
R8274:Csmd1	UTSW	8	15,910,453 (GRCm38)	missense	possibly damaging	0.93
R8286:Csmd1	UTSW	8	15,989,188 (GRCm38)	missense	probably benign	0.18
R8289:Csmd1	UTSW	8	16,058,702 (GRCm38)	missense	probably damaging	0.99
R8314:Csmd1	UTSW	8	16,158,244 (GRCm38)	missense	probably benign
R8323:Csmd1	UTSW	8	17,216,735 (GRCm38)	nonsense	probably null
R8387:Csmd1	UTSW	8	16,000,484 (GRCm38)	missense	possibly damaging	0.94
R8413:Csmd1	UTSW	8	15,900,676 (GRCm38)	missense	probably damaging	0.98
R8672:Csmd1	UTSW	8	15,926,598 (GRCm38)	missense	probably benign	0.01
R8765:Csmd1	UTSW	8	16,710,611 (GRCm38)	nonsense	probably null
R8789:Csmd1	UTSW	8	17,216,706 (GRCm38)	missense	probably damaging	0.99
R8828:Csmd1	UTSW	8	15,998,794 (GRCm38)	missense	probably benign	0.00
R8858:Csmd1	UTSW	8	16,070,304 (GRCm38)	missense	probably benign	0.10
R8878:Csmd1	UTSW	8	15,910,528 (GRCm38)	missense	probably damaging	1.00
R8911:Csmd1	UTSW	8	16,698,003 (GRCm38)	missense	probably damaging	0.99
R8966:Csmd1	UTSW	8	16,200,045 (GRCm38)	missense	probably damaging	1.00
R8978:Csmd1	UTSW	8	15,921,056 (GRCm38)	missense	probably benign	0.37
R8996:Csmd1	UTSW	8	15,921,105 (GRCm38)	missense	possibly damaging	0.54
R9045:Csmd1	UTSW	8	16,234,074 (GRCm38)	missense	probably damaging	0.99
R9084:Csmd1	UTSW	8	16,088,311 (GRCm38)	missense	probably benign
R9124:Csmd1	UTSW	8	15,984,806 (GRCm38)	missense	probably damaging	0.99
R9127:Csmd1	UTSW	8	16,223,272 (GRCm38)	missense	probably benign	0.31
R9146:Csmd1	UTSW	8	15,998,832 (GRCm38)	missense	probably benign	0.00
R9198:Csmd1	UTSW	8	15,912,430 (GRCm38)	missense	probably damaging	1.00
R9285:Csmd1	UTSW	8	15,906,088 (GRCm38)	missense	probably damaging	1.00
R9303:Csmd1	UTSW	8	15,961,532 (GRCm38)	missense	probably benign	0.31
R9305:Csmd1	UTSW	8	15,961,532 (GRCm38)	missense	probably benign	0.31
R9326:Csmd1	UTSW	8	15,999,803 (GRCm38)	missense	probably benign	0.21
R9356:Csmd1	UTSW	8	16,202,055 (GRCm38)	missense	probably damaging	1.00
R9385:Csmd1	UTSW	8	15,984,756 (GRCm38)	missense	probably benign	0.19
R9444:Csmd1	UTSW	8	16,158,236 (GRCm38)	missense	probably benign	0.30
R9476:Csmd1	UTSW	8	15,931,215 (GRCm38)	critical splice acceptor site	probably null
R9506:Csmd1	UTSW	8	16,200,009 (GRCm38)	missense	probably damaging	1.00
R9614:Csmd1	UTSW	8	16,158,225 (GRCm38)	missense	probably benign	0.00
R9668:Csmd1	UTSW	8	16,211,758 (GRCm38)	missense	probably benign	0.00
X0011:Csmd1	UTSW	8	16,196,263 (GRCm38)	missense	probably damaging	1.00
X0021:Csmd1	UTSW	8	16,185,256 (GRCm38)	missense	probably damaging	1.00
X0024:Csmd1	UTSW	8	16,037,218 (GRCm38)	missense	probably damaging	0.99
X0028:Csmd1	UTSW	8	15,915,333 (GRCm38)	missense	possibly damaging	0.79
Z1088:Csmd1	UTSW	8	16,189,978 (GRCm38)	missense	possibly damaging	0.50
Z1088:Csmd1	UTSW	8	16,092,258 (GRCm38)	missense	probably damaging	1.00
Z1088:Csmd1	UTSW	8	15,921,875 (GRCm38)	missense	possibly damaging	0.91
Z1088:Csmd1	UTSW	8	16,346,617 (GRCm38)	missense	probably damaging	0.99
Z1088:Csmd1	UTSW	8	16,200,058 (GRCm38)	missense	probably damaging	0.97
Z1176:Csmd1	UTSW	8	16,037,198 (GRCm38)	missense	probably damaging	1.00
Z1176:Csmd1	UTSW	8	15,998,814 (GRCm38)	missense	probably damaging	1.00
Z1177:Csmd1	UTSW	8	16,200,019 (GRCm38)	missense	probably damaging	1.00
Z1177:Csmd1	UTSW	8	15,984,708 (GRCm38)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- TTCAGTTAGTCCTCATGCAAATCAG -3'
(R):5'- TTCAACCAAACCTTGACTACTCATG -3'

Sequencing Primer
(F):5'- GTCCTCATGCAAATCAGAGTGGTC -3'
(R):5'- CTCATGTAGTGACTAGAAGCAGCTTG -3'

Posted On

2019-10-24