Mutagenetix > Incidental Mutation

Incidental Mutation 'R7604:Sdk2'

588188

Institutional Source

Beutler Lab

Gene Symbol

Sdk2

Ensembl Gene

ENSMUSG00000041592

Gene Name

sidekick cell adhesion molecule 2

Synonyms

5330435L01Rik, 4632412F08Rik

MMRRC Submission

045644-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.100) question?

Stock #

R7604 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

113776374-114067046 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

C to T at 113829969 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Arginine to Histidine at position 1378 (R1378H)

Ref Sequence

ENSEMBL: ENSMUSP00000038972 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000041627]

AlphaFold

Q6V4S5

Predicted Effect

possibly damaging
Transcript: ENSMUST00000041627
AA Change: R1378H

PolyPhen 2 Score 0.910 (Sensitivity: 0.81; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000038972
Gene: ENSMUSG00000041592
AA Change: R1378H

Domain	Start	End	E-Value	Type
signal peptide	1	24	N/A	INTRINSIC
IGc2	43	102	4.67e-4	SMART
IG	123	208	6.07e-3	SMART
IG	225	309	1.4e-7	SMART
IGc2	325	391	6.21e-9	SMART
IGc2	418	486	8.57e-12	SMART
IG	506	591	2.37e-5	SMART
FN3	594	678	1.91e-7	SMART
FN3	694	780	2.42e-9	SMART
FN3	796	884	3.45e-5	SMART
FN3	899	981	2.36e-12	SMART
FN3	997	1084	1.64e-6	SMART
FN3	1101	1188	8.83e-12	SMART
FN3	1204	1289	3.62e-8	SMART
FN3	1305	1388	1.74e-10	SMART
FN3	1404	1489	8.23e-12	SMART
FN3	1506	1612	3.62e-8	SMART
FN3	1628	1713	1.15e-10	SMART
FN3	1728	1815	2.17e-11	SMART
FN3	1829	1913	5.04e-7	SMART
transmembrane domain	1935	1957	N/A	INTRINSIC
low complexity region	2138	2153	N/A	INTRINSIC

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.7%
20x: 99.1%

Validation Efficiency

100% (73/73)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a member of the immunoglobulin superfamily. The protein contains two immunoglobulin domains and thirteen fibronectin type III domains. Fibronectin type III domains are present in both extracellular and intracellular proteins and tandem repeats are known to contain binding sites for DNA, heparin and the cell surface. This protein, and a homologous mouse sequence, are very similar to the Drosophila sidekick gene product but the specific function of this superfamily member is not yet known. Evidence for alternative splicing at this gene locus has been observed but the full-length nature of additional variants has not yet been determined. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired interconnectvity between VG3 amacrine cells and W3B retinal ganglion cells. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 74 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930503B20Rik	A	T	3: 146,650,660 (GRCm38)	Y164*	probably null	Het
Abce1	G	A	8: 79,699,374 (GRCm38)	T258M	probably benign	Het
Actl7b	G	C	4: 56,740,693 (GRCm38)	P222A	probably benign	Het
Adam2	T	C	14: 66,056,541 (GRCm38)	N279S	probably benign	Het
Adamts13	A	G	2: 27,005,206 (GRCm38)	D1103G	probably benign	Het
Aff1	G	A	5: 103,847,809 (GRCm38)	S1089N	probably benign	Het
Ahcyl2	T	C	6: 29,768,556 (GRCm38)	S7P	unknown	Het
Anks1b	A	G	10: 90,260,846 (GRCm38)		probably null	Het
Azin1	A	C	15: 38,491,634 (GRCm38)	D359E	probably damaging	Het
Bahd1	A	G	2: 118,916,310 (GRCm38)	T137A	probably benign	Het
Bltp1	A	G	3: 36,949,843 (GRCm38)		probably null	Het
C1qbp	A	G	11: 70,978,772 (GRCm38)	S162P	probably damaging	Het
C1rb	A	G	6: 124,580,484 (GRCm38)	M527V	not run	Het
Ccdc88c	A	T	12: 100,930,547 (GRCm38)	D1381E	probably damaging	Het
Ccdc90b	A	G	7: 92,578,530 (GRCm38)	Y234C	probably damaging	Het
Cfap91	C	A	16: 38,298,236 (GRCm38)	E734*	probably null	Het
Cyp11b2	A	T	15: 74,853,750 (GRCm38)		probably null	Het
Dchs1	A	G	7: 105,765,982 (GRCm38)	V665A	probably damaging	Het
Dhx8	T	C	11: 101,764,797 (GRCm38)	S1119P	probably damaging	Het
Dnah6	T	C	6: 73,092,168 (GRCm38)	D2512G	probably damaging	Het
Dnah8	T	C	17: 30,813,095 (GRCm38)	Y4130H	probably damaging	Het
E4f1	G	T	17: 24,455,233 (GRCm38)	A19D	unknown	Het
Eftud2	T	C	11: 102,848,012 (GRCm38)	D517G	possibly damaging	Het
Epha6	T	A	16: 60,205,772 (GRCm38)	I436F	possibly damaging	Het
Epha7	C	T	4: 28,871,937 (GRCm38)	S422L	probably benign	Het
Ezh1	A	G	11: 101,217,029 (GRCm38)	M74T	probably benign	Het
Galnt14	T	A	17: 73,504,921 (GRCm38)	K435M	possibly damaging	Het
Garin2	C	A	12: 78,715,014 (GRCm38)	Q151K	probably damaging	Het
Gde1	A	T	7: 118,705,536 (GRCm38)	Y39N	possibly damaging	Het
Gldn	G	A	9: 54,338,593 (GRCm38)	R476Q	probably benign	Het
Gm32742	G	T	9: 51,156,762 (GRCm38)	R307S	probably benign	Het
Gnao1	T	G	8: 93,944,344 (GRCm38)	N150K		Het
Gpr135	A	T	12: 72,069,867 (GRCm38)	D375E	possibly damaging	Het
Gria4	A	G	9: 4,464,315 (GRCm38)	M549T	probably damaging	Het
Grik3	C	A	4: 125,623,635 (GRCm38)	D90E	probably damaging	Het
Hivep3	CGG	CG	4: 120,097,911 (GRCm38)	1141	probably null	Het
Hspd1	T	C	1: 55,080,337 (GRCm38)	E327G	probably benign	Het
Kif6	T	C	17: 49,671,101 (GRCm38)	I107T	probably damaging	Het
Kmt2e	C	T	5: 23,501,765 (GRCm38)	T1442M	not run	Het
Lama3	C	T	18: 12,500,493 (GRCm38)	H1561Y	possibly damaging	Het
Lpcat3	A	G	6: 124,702,530 (GRCm38)	N331S	probably benign	Het
Lrrc63	C	A	14: 75,084,969 (GRCm38)	W565L	possibly damaging	Het
Malrd1	A	G	2: 15,925,192 (GRCm38)	N1503S	unknown	Het
Mcm7	C	T	5: 138,169,724 (GRCm38)	V38I	probably benign	Het
Mphosph9	C	T	5: 124,316,117 (GRCm38)	V106I	probably benign	Het
Mroh8	G	T	2: 157,269,564 (GRCm38)	L157I	possibly damaging	Het
Mta2	T	A	19: 8,945,836 (GRCm38)	S91T	probably damaging	Het
Muc5ac	A	T	7: 141,809,709 (GRCm38)	Q2252H	unknown	Het
Ndufs7	G	T	10: 80,253,697 (GRCm38)	V59L	probably benign	Het
Nrxn2	T	C	19: 6,531,961 (GRCm38)	L1642P	probably damaging	Het
Or8k21	G	A	2: 86,314,900 (GRCm38)	P129S	probably damaging	Het
Pbxip1	A	T	3: 89,445,595 (GRCm38)	I183L	probably benign	Het
Peak1	A	T	9: 56,241,207 (GRCm38)	L1085*	probably null	Het
Phf20l1	A	G	15: 66,604,084 (GRCm38)	T189A	probably benign	Het
Poteg	T	A	8: 27,458,655 (GRCm38)		probably null	Het
Proc	G	A	18: 32,134,778 (GRCm38)		probably null	Het
Prr36	G	A	8: 4,214,836 (GRCm38)	R277C	unknown	Het
Ptpn3	T	C	4: 57,240,845 (GRCm38)	N257D	probably damaging	Het
Rnf5	C	A	17: 34,601,664 (GRCm38)	V150L	probably benign	Het
Sbf2	T	A	7: 110,378,067 (GRCm38)	Q666L	possibly damaging	Het
Selplg	GTCTGCCTCCATGGGTGCTGGCTGCGAGGTCTCTGCCTCCATGGGTGCTGGCTGCGAGGTCTCTGCCTCCATGGGTGCTGGCTGCGAGGTCTCTGCCTCCATGGGTGCTGGCTGCGAGGTCTCT	GTCTGCCTCCATGGGTGCTGGCTGCGAGGTCTCTGCCTCCATGGGTGCTGGCTGCGAGGTCTCTGCCTCCATGGGTGCTGGCTGCGAGGTCTCT	5: 113,819,695 (GRCm38)		probably benign	Het
Sipa1l2	A	T	8: 125,419,272 (GRCm38)	V1681E	probably benign	Het
Slc15a5	A	T	6: 138,079,786 (GRCm38)	L44Q	probably damaging	Het
Slc29a1	C	A	17: 45,592,324 (GRCm38)		probably null	Het
Slc5a8	G	T	10: 88,904,960 (GRCm38)	V246F	possibly damaging	Het
Spint2	T	C	7: 29,258,519 (GRCm38)	E154G	probably damaging	Het
Sycp1	A	T	3: 102,913,433 (GRCm38)	S413T	probably damaging	Het
Tpsg1	G	T	17: 25,373,210 (GRCm38)	G86V	probably damaging	Het
Trio	A	T	15: 27,736,445 (GRCm38)		probably null	Het
Unc13b	A	G	4: 43,256,776 (GRCm38)	T1155A	possibly damaging	Het
Unc13b	A	G	4: 43,170,102 (GRCm38)	Y310C	unknown	Het
Vmn2r79	A	G	7: 87,003,384 (GRCm38)		probably null	Het
Xpo7	T	A	14: 70,671,670 (GRCm38)	S803C	probably damaging	Het
Zfp747l1	T	C	7: 127,386,535 (GRCm38)	T95A	unknown	Het

Other mutations in Sdk2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00972:Sdk2	APN	11	113,854,384 (GRCm38)	missense	possibly damaging	0.86
IGL01063:Sdk2	APN	11	113,830,842 (GRCm38)	missense	probably damaging	1.00
IGL01291:Sdk2	APN	11	113,843,080 (GRCm38)	missense	probably benign
IGL01316:Sdk2	APN	11	113,867,965 (GRCm38)	missense	probably benign	0.09
IGL01614:Sdk2	APN	11	113,793,858 (GRCm38)	missense	probably damaging	1.00
IGL01998:Sdk2	APN	11	113,838,532 (GRCm38)	missense	probably damaging	0.98
IGL02014:Sdk2	APN	11	113,838,494 (GRCm38)	missense	probably damaging	1.00
IGL02095:Sdk2	APN	11	113,834,830 (GRCm38)	missense	probably damaging	1.00
IGL02115:Sdk2	APN	11	113,834,813 (GRCm38)	splice site	probably benign
IGL02543:Sdk2	APN	11	113,868,921 (GRCm38)	missense	possibly damaging	0.90
IGL02976:Sdk2	APN	11	113,851,842 (GRCm38)	missense	probably damaging	1.00
IGL03001:Sdk2	APN	11	113,821,626 (GRCm38)	missense	probably benign	0.00
IGL03122:Sdk2	APN	11	113,842,068 (GRCm38)	missense	probably damaging	1.00
IGL03183:Sdk2	APN	11	113,850,984 (GRCm38)	missense	probably benign	0.19
IGL03222:Sdk2	APN	11	113,838,431 (GRCm38)	missense	probably benign	0.01
IGL03310:Sdk2	APN	11	113,793,325 (GRCm38)	missense	possibly damaging	0.77
Curtailed	UTSW	11	113,851,800 (GRCm38)	missense	probably damaging	1.00
Trimmed	UTSW	11	113,856,696 (GRCm38)	nonsense	probably null
ANU05:Sdk2	UTSW	11	113,843,080 (GRCm38)	missense	probably benign
BB008:Sdk2	UTSW	11	113,893,441 (GRCm38)	missense	possibly damaging	0.79
BB018:Sdk2	UTSW	11	113,893,441 (GRCm38)	missense	possibly damaging	0.79
R0008:Sdk2	UTSW	11	113,856,755 (GRCm38)	missense	probably damaging	1.00
R0008:Sdk2	UTSW	11	113,856,755 (GRCm38)	missense	probably damaging	1.00
R0088:Sdk2	UTSW	11	113,827,086 (GRCm38)	missense	possibly damaging	0.74
R0096:Sdk2	UTSW	11	113,903,144 (GRCm38)	splice site	probably benign
R0386:Sdk2	UTSW	11	113,893,464 (GRCm38)	missense	probably damaging	0.96
R0396:Sdk2	UTSW	11	113,829,967 (GRCm38)	missense	probably benign	0.04
R0409:Sdk2	UTSW	11	113,850,891 (GRCm38)	splice site	probably benign
R0416:Sdk2	UTSW	11	113,803,203 (GRCm38)	missense	probably damaging	1.00
R0456:Sdk2	UTSW	11	113,791,466 (GRCm38)	missense	possibly damaging	0.93
R0544:Sdk2	UTSW	11	113,781,010 (GRCm38)	missense	probably damaging	1.00
R0691:Sdk2	UTSW	11	113,794,920 (GRCm38)	splice site	probably null
R0711:Sdk2	UTSW	11	113,903,144 (GRCm38)	splice site	probably benign
R0717:Sdk2	UTSW	11	113,832,326 (GRCm38)	missense	probably damaging	1.00
R0780:Sdk2	UTSW	11	113,893,508 (GRCm38)	missense	probably benign	0.07
R0831:Sdk2	UTSW	11	113,832,258 (GRCm38)	missense	probably damaging	0.96
R0853:Sdk2	UTSW	11	113,821,415 (GRCm38)	missense	probably benign	0.00
R0865:Sdk2	UTSW	11	113,850,922 (GRCm38)	missense	probably benign	0.12
R0930:Sdk2	UTSW	11	113,838,445 (GRCm38)	missense	probably benign	0.01
R0964:Sdk2	UTSW	11	113,806,417 (GRCm38)	splice site	probably benign
R1051:Sdk2	UTSW	11	113,838,646 (GRCm38)	synonymous	silent
R1052:Sdk2	UTSW	11	113,838,646 (GRCm38)	synonymous	silent
R1054:Sdk2	UTSW	11	113,838,646 (GRCm38)	synonymous	silent
R1055:Sdk2	UTSW	11	113,838,646 (GRCm38)	synonymous	silent
R1077:Sdk2	UTSW	11	113,838,646 (GRCm38)	synonymous	silent
R1079:Sdk2	UTSW	11	113,838,646 (GRCm38)	synonymous	silent
R1115:Sdk2	UTSW	11	113,838,646 (GRCm38)	synonymous	silent
R1186:Sdk2	UTSW	11	113,838,646 (GRCm38)	synonymous	silent
R1187:Sdk2	UTSW	11	113,838,646 (GRCm38)	synonymous	silent
R1337:Sdk2	UTSW	11	113,832,331 (GRCm38)	missense	possibly damaging	0.79
R1430:Sdk2	UTSW	11	113,838,646 (GRCm38)	synonymous	silent
R1433:Sdk2	UTSW	11	113,795,045 (GRCm38)	missense	probably damaging	0.99
R1464:Sdk2	UTSW	11	113,830,080 (GRCm38)	missense	possibly damaging	0.86
R1464:Sdk2	UTSW	11	113,830,080 (GRCm38)	missense	possibly damaging	0.86
R1497:Sdk2	UTSW	11	113,893,575 (GRCm38)	splice site	probably benign
R1514:Sdk2	UTSW	11	113,838,646 (GRCm38)	synonymous	silent
R1529:Sdk2	UTSW	11	113,838,646 (GRCm38)	synonymous	silent
R1596:Sdk2	UTSW	11	113,838,609 (GRCm38)	splice site	probably benign
R1680:Sdk2	UTSW	11	113,838,646 (GRCm38)	synonymous	silent
R1680:Sdk2	UTSW	11	113,791,436 (GRCm38)	missense	possibly damaging	0.47
R1770:Sdk2	UTSW	11	113,793,741 (GRCm38)	missense	probably benign	0.05
R1858:Sdk2	UTSW	11	113,838,646 (GRCm38)	synonymous	silent
R1866:Sdk2	UTSW	11	113,838,646 (GRCm38)	synonymous	silent
R1874:Sdk2	UTSW	11	113,834,956 (GRCm38)	missense	probably benign	0.00
R1899:Sdk2	UTSW	11	113,838,646 (GRCm38)	synonymous	silent
R1905:Sdk2	UTSW	11	113,838,646 (GRCm38)	synonymous	silent
R1907:Sdk2	UTSW	11	113,838,646 (GRCm38)	synonymous	silent
R1913:Sdk2	UTSW	11	113,856,726 (GRCm38)	missense	possibly damaging	0.77
R1964:Sdk2	UTSW	11	113,781,017 (GRCm38)	nonsense	probably null
R2055:Sdk2	UTSW	11	113,850,954 (GRCm38)	missense	probably damaging	1.00
R2059:Sdk2	UTSW	11	113,854,332 (GRCm38)	missense	probably damaging	1.00
R2093:Sdk2	UTSW	11	113,943,122 (GRCm38)	missense	probably damaging	1.00
R2256:Sdk2	UTSW	11	113,830,794 (GRCm38)	missense	probably benign	0.44
R3720:Sdk2	UTSW	11	113,800,244 (GRCm38)	missense	probably damaging	1.00
R3795:Sdk2	UTSW	11	113,856,696 (GRCm38)	nonsense	probably null
R4037:Sdk2	UTSW	11	113,795,055 (GRCm38)	missense	probably damaging	1.00
R4171:Sdk2	UTSW	11	113,866,989 (GRCm38)	splice site	probably null
R4717:Sdk2	UTSW	11	113,854,369 (GRCm38)	missense	probably damaging	0.96
R4758:Sdk2	UTSW	11	113,827,054 (GRCm38)	missense	possibly damaging	0.87
R4857:Sdk2	UTSW	11	113,821,382 (GRCm38)	nonsense	probably null
R4924:Sdk2	UTSW	11	113,857,758 (GRCm38)	missense	probably damaging	1.00
R5015:Sdk2	UTSW	11	113,793,761 (GRCm38)	missense	probably damaging	1.00
R5171:Sdk2	UTSW	11	113,850,982 (GRCm38)	missense	probably benign	0.01
R5239:Sdk2	UTSW	11	113,868,033 (GRCm38)	missense	probably damaging	1.00
R5243:Sdk2	UTSW	11	113,825,086 (GRCm38)	missense	possibly damaging	0.76
R5279:Sdk2	UTSW	11	113,867,031 (GRCm38)	missense	probably benign	0.31
R5535:Sdk2	UTSW	11	113,943,158 (GRCm38)	missense	possibly damaging	0.80
R5634:Sdk2	UTSW	11	113,851,714 (GRCm38)	missense	probably damaging	1.00
R5637:Sdk2	UTSW	11	113,833,179 (GRCm38)	missense	probably damaging	1.00
R5726:Sdk2	UTSW	11	113,851,800 (GRCm38)	missense	probably damaging	1.00
R5793:Sdk2	UTSW	11	113,868,952 (GRCm38)	missense	possibly damaging	0.46
R5798:Sdk2	UTSW	11	113,827,116 (GRCm38)	missense	probably damaging	1.00
R5834:Sdk2	UTSW	11	113,854,273 (GRCm38)	missense	probably damaging	1.00
R5863:Sdk2	UTSW	11	113,834,984 (GRCm38)	missense	probably damaging	0.98
R5869:Sdk2	UTSW	11	113,851,882 (GRCm38)	missense	probably damaging	0.96
R5875:Sdk2	UTSW	11	113,830,059 (GRCm38)	missense	probably benign	0.00
R5953:Sdk2	UTSW	11	113,793,744 (GRCm38)	missense	probably damaging	1.00
R5991:Sdk2	UTSW	11	113,943,254 (GRCm38)	missense	probably damaging	0.97
R6018:Sdk2	UTSW	11	113,830,063 (GRCm38)	missense	probably benign	0.00
R6116:Sdk2	UTSW	11	113,854,364 (GRCm38)	missense	probably damaging	0.99
R6328:Sdk2	UTSW	11	113,793,755 (GRCm38)	missense	probably damaging	1.00
R6348:Sdk2	UTSW	11	113,893,508 (GRCm38)	missense	probably benign	0.07
R6383:Sdk2	UTSW	11	113,832,265 (GRCm38)	missense	probably damaging	1.00
R6824:Sdk2	UTSW	11	113,867,934 (GRCm38)	missense	probably benign	0.43
R6835:Sdk2	UTSW	11	113,830,048 (GRCm38)	missense	probably damaging	0.98
R6853:Sdk2	UTSW	11	113,780,929 (GRCm38)	missense	probably damaging	0.99
R6912:Sdk2	UTSW	11	113,903,120 (GRCm38)	missense	probably benign	0.03
R7000:Sdk2	UTSW	11	113,803,169 (GRCm38)	missense	probably damaging	1.00
R7099:Sdk2	UTSW	11	113,834,905 (GRCm38)	missense	probably damaging	0.98
R7102:Sdk2	UTSW	11	113,842,690 (GRCm38)	nonsense	probably null
R7177:Sdk2	UTSW	11	113,829,969 (GRCm38)	missense	possibly damaging	0.91
R7381:Sdk2	UTSW	11	113,838,489 (GRCm38)	missense	probably damaging	0.98
R7412:Sdk2	UTSW	11	113,868,083 (GRCm38)	splice site	probably null
R7504:Sdk2	UTSW	11	113,867,967 (GRCm38)	missense	possibly damaging	0.50
R7552:Sdk2	UTSW	11	113,873,213 (GRCm38)	missense	possibly damaging	0.63
R7647:Sdk2	UTSW	11	113,793,737 (GRCm38)	missense	probably damaging	1.00
R7897:Sdk2	UTSW	11	113,873,201 (GRCm38)	missense	possibly damaging	0.50
R7931:Sdk2	UTSW	11	113,893,441 (GRCm38)	missense	possibly damaging	0.79
R7998:Sdk2	UTSW	11	113,859,938 (GRCm38)	missense	probably benign	0.18
R8052:Sdk2	UTSW	11	113,854,351 (GRCm38)	missense	probably damaging	1.00
R8053:Sdk2	UTSW	11	113,854,351 (GRCm38)	missense	probably damaging	1.00
R8084:Sdk2	UTSW	11	113,827,089 (GRCm38)	missense	possibly damaging	0.67
R8136:Sdk2	UTSW	11	113,851,713 (GRCm38)	missense	probably damaging	1.00
R8151:Sdk2	UTSW	11	113,872,857 (GRCm38)	missense	possibly damaging	0.84
R8394:Sdk2	UTSW	11	113,838,716 (GRCm38)	missense	probably benign
R8715:Sdk2	UTSW	11	113,780,902 (GRCm38)	missense	probably damaging	1.00
R8774:Sdk2	UTSW	11	113,839,343 (GRCm38)	missense	probably damaging	1.00
R8774-TAIL:Sdk2	UTSW	11	113,839,343 (GRCm38)	missense	probably damaging	1.00
R8804:Sdk2	UTSW	11	113,873,152 (GRCm38)	nonsense	probably null
R9136:Sdk2	UTSW	11	113,806,377 (GRCm38)	missense	probably damaging	1.00
R9147:Sdk2	UTSW	11	113,823,400 (GRCm38)	missense	probably benign	0.18
R9300:Sdk2	UTSW	11	113,825,030 (GRCm38)	missense	possibly damaging	0.63
R9354:Sdk2	UTSW	11	113,834,931 (GRCm38)	missense	probably benign	0.00
R9450:Sdk2	UTSW	11	113,806,279 (GRCm38)	missense	probably benign
R9462:Sdk2	UTSW	11	113,869,918 (GRCm38)	missense	possibly damaging	0.56
R9616:Sdk2	UTSW	11	113,800,235 (GRCm38)	missense	probably benign	0.05
R9678:Sdk2	UTSW	11	113,794,963 (GRCm38)	nonsense	probably null
RF002:Sdk2	UTSW	11	113,885,252 (GRCm38)	missense	probably benign	0.00
V1662:Sdk2	UTSW	11	113,834,908 (GRCm38)	missense	probably damaging	1.00
Z1176:Sdk2	UTSW	11	113,851,836 (GRCm38)	missense	probably damaging	0.97
Z1176:Sdk2	UTSW	11	113,839,322 (GRCm38)	missense	probably benign	0.41
Z1177:Sdk2	UTSW	11	113,859,956 (GRCm38)	missense	probably benign
Z1177:Sdk2	UTSW	11	113,839,320 (GRCm38)	missense	probably damaging	1.00
Z1177:Sdk2	UTSW	11	113,838,659 (GRCm38)	missense	probably damaging	0.99

Predicted Primers

PCR Primer
(F):5'- ACTAAAGCAATGCCGTTCCC -3'
(R):5'- TGCAACCACAGAGATGGGTC -3'

Sequencing Primer
(F):5'- AATGCCGTTCCCCACCG -3'
(R):5'- ACAGAGATGGGTCCTCTCACAG -3'

Posted On

2019-10-24