Incidental Mutation 'R7613:Adgrb2'
| ID |
588715 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Adgrb2
|
| Ensembl Gene |
ENSMUSG00000028782 |
| Gene Name |
adhesion G protein-coupled receptor B2 |
| Synonyms |
Bai2 |
| MMRRC Submission |
045681-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7613 (G1)
|
| Quality Score |
217.468 |
|
Status
|
Validated
|
| Chromosome |
4 |
| Chromosomal Location |
129878663-129916426 bp(+) (GRCm39) |
| Type of Mutation |
critical splice acceptor site |
| DNA Base Change (assembly) |
CTATA to CTATATA
at 129915006 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000112524
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000030571]
[ENSMUST00000097868]
[ENSMUST00000106015]
[ENSMUST00000106017]
[ENSMUST00000106018]
[ENSMUST00000120204]
[ENSMUST00000121049]
|
| AlphaFold |
Q8CGM1 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000030571
|
| SMART Domains |
Protein: ENSMUSP00000030571
Gene: ENSMUSG00000028782
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
low complexity region
|
117 |
127 |
N/A |
INTRINSIC |
|
low complexity region
|
160 |
173 |
N/A |
INTRINSIC |
|
low complexity region
|
197 |
208 |
N/A |
INTRINSIC |
|
low complexity region
|
272 |
278 |
N/A |
INTRINSIC |
|
TSP1
|
303 |
353 |
9.52e-11 |
SMART |
|
TSP1
|
358 |
408 |
1.86e-13 |
SMART |
|
TSP1
|
413 |
463 |
9.89e-9 |
SMART |
|
TSP1
|
469 |
519 |
3.09e-10 |
SMART |
|
HormR
|
521 |
587 |
3.27e-18 |
SMART |
|
Pfam:GAIN
|
600 |
842 |
1.6e-41 |
PFAM |
|
GPS
|
864 |
917 |
2.57e-19 |
SMART |
|
Pfam:7tm_2
|
923 |
1192 |
1.7e-67 |
PFAM |
|
low complexity region
|
1357 |
1371 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000097868
|
| SMART Domains |
Protein: ENSMUSP00000095480
Gene: ENSMUSG00000028782
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
low complexity region
|
117 |
127 |
N/A |
INTRINSIC |
|
low complexity region
|
160 |
173 |
N/A |
INTRINSIC |
|
low complexity region
|
197 |
208 |
N/A |
INTRINSIC |
|
low complexity region
|
272 |
278 |
N/A |
INTRINSIC |
|
TSP1
|
303 |
353 |
9.52e-11 |
SMART |
|
TSP1
|
358 |
408 |
1.86e-13 |
SMART |
|
TSP1
|
413 |
463 |
9.89e-9 |
SMART |
|
TSP1
|
469 |
519 |
3.09e-10 |
SMART |
|
HormR
|
521 |
587 |
3.27e-18 |
SMART |
|
Pfam:DUF3497
|
597 |
859 |
1.2e-54 |
PFAM |
|
GPS
|
864 |
917 |
2.57e-19 |
SMART |
|
Pfam:7tm_2
|
923 |
1159 |
2.6e-69 |
PFAM |
|
low complexity region
|
1324 |
1338 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000106015
|
| SMART Domains |
Protein: ENSMUSP00000101636
Gene: ENSMUSG00000028782
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
low complexity region
|
117 |
127 |
N/A |
INTRINSIC |
|
low complexity region
|
160 |
173 |
N/A |
INTRINSIC |
|
low complexity region
|
197 |
208 |
N/A |
INTRINSIC |
|
low complexity region
|
272 |
278 |
N/A |
INTRINSIC |
|
TSP1
|
303 |
353 |
9.52e-11 |
SMART |
|
TSP1
|
358 |
408 |
1.86e-13 |
SMART |
|
TSP1
|
413 |
463 |
9.89e-9 |
SMART |
|
TSP1
|
469 |
519 |
3.09e-10 |
SMART |
|
HormR
|
521 |
587 |
3.27e-18 |
SMART |
|
Pfam:DUF3497
|
597 |
859 |
6.4e-55 |
PFAM |
|
GPS
|
864 |
917 |
2.57e-19 |
SMART |
|
Pfam:7tm_2
|
923 |
1192 |
4.1e-68 |
PFAM |
|
low complexity region
|
1357 |
1371 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000106017
|
| SMART Domains |
Protein: ENSMUSP00000101638
Gene: ENSMUSG00000028782
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
low complexity region
|
117 |
127 |
N/A |
INTRINSIC |
|
low complexity region
|
160 |
173 |
N/A |
INTRINSIC |
|
low complexity region
|
197 |
208 |
N/A |
INTRINSIC |
|
low complexity region
|
272 |
278 |
N/A |
INTRINSIC |
|
TSP1
|
303 |
353 |
9.52e-11 |
SMART |
|
TSP1
|
358 |
408 |
1.86e-13 |
SMART |
|
TSP1
|
413 |
463 |
9.89e-9 |
SMART |
|
TSP1
|
469 |
519 |
3.09e-10 |
SMART |
|
HormR
|
521 |
587 |
3.27e-18 |
SMART |
|
Pfam:DUF3497
|
597 |
859 |
6.3e-55 |
PFAM |
|
GPS
|
864 |
917 |
2.57e-19 |
SMART |
|
Pfam:7tm_2
|
923 |
1180 |
4.6e-68 |
PFAM |
|
low complexity region
|
1345 |
1359 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000106018
|
| SMART Domains |
Protein: ENSMUSP00000101639
Gene: ENSMUSG00000028782
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
low complexity region
|
117 |
127 |
N/A |
INTRINSIC |
|
low complexity region
|
160 |
173 |
N/A |
INTRINSIC |
|
low complexity region
|
197 |
208 |
N/A |
INTRINSIC |
|
low complexity region
|
272 |
278 |
N/A |
INTRINSIC |
|
TSP1
|
303 |
353 |
1.86e-13 |
SMART |
|
TSP1
|
358 |
408 |
9.89e-9 |
SMART |
|
TSP1
|
414 |
464 |
3.09e-10 |
SMART |
|
HormR
|
466 |
532 |
3.27e-18 |
SMART |
|
Pfam:DUF3497
|
542 |
804 |
1.1e-54 |
PFAM |
|
GPS
|
809 |
862 |
2.57e-19 |
SMART |
|
Pfam:7tm_2
|
868 |
1104 |
2.4e-69 |
PFAM |
|
low complexity region
|
1269 |
1283 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000120204
|
| SMART Domains |
Protein: ENSMUSP00000112524
Gene: ENSMUSG00000028782
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
low complexity region
|
117 |
127 |
N/A |
INTRINSIC |
|
low complexity region
|
160 |
173 |
N/A |
INTRINSIC |
|
low complexity region
|
197 |
208 |
N/A |
INTRINSIC |
|
low complexity region
|
272 |
278 |
N/A |
INTRINSIC |
|
TSP1
|
303 |
353 |
9.52e-11 |
SMART |
|
TSP1
|
358 |
408 |
9.89e-9 |
SMART |
|
TSP1
|
414 |
464 |
3.09e-10 |
SMART |
|
HormR
|
466 |
532 |
3.27e-18 |
SMART |
|
Pfam:DUF3497
|
542 |
804 |
8.2e-55 |
PFAM |
|
GPS
|
809 |
862 |
2.57e-19 |
SMART |
|
Pfam:7tm_2
|
868 |
1104 |
9.6e-70 |
PFAM |
|
low complexity region
|
1269 |
1283 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000121049
|
| SMART Domains |
Protein: ENSMUSP00000112869
Gene: ENSMUSG00000028782
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
low complexity region
|
117 |
127 |
N/A |
INTRINSIC |
|
low complexity region
|
160 |
173 |
N/A |
INTRINSIC |
|
low complexity region
|
197 |
208 |
N/A |
INTRINSIC |
|
low complexity region
|
272 |
278 |
N/A |
INTRINSIC |
|
TSP1
|
303 |
353 |
1.86e-13 |
SMART |
|
TSP1
|
358 |
408 |
9.89e-9 |
SMART |
|
TSP1
|
414 |
464 |
3.09e-10 |
SMART |
|
HormR
|
466 |
532 |
3.27e-18 |
SMART |
|
Pfam:DUF3497
|
542 |
804 |
6.1e-55 |
PFAM |
|
GPS
|
809 |
862 |
2.57e-19 |
SMART |
|
Pfam:7tm_2
|
868 |
1137 |
3.8e-68 |
PFAM |
|
low complexity region
|
1302 |
1316 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
100% (52/52) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a a seven-span transmembrane protein that is thought to be a member of the secretin receptor family. The encoded protein is a brain-specific inhibitor of angiogenesis. The mature peptide may be further cleaved into additional products (PMID:20367554). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
PHENOTYPE: Mice homozygous for disruptions in this gene show a lessening of depression like behavior. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 52 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acta2 |
G |
A |
19: 34,229,931 (GRCm39) |
T8I |
probably benign |
Het |
| Adh1 |
T |
A |
3: 137,992,592 (GRCm39) |
L236* |
probably null |
Het |
| Akt2 |
A |
G |
7: 27,336,595 (GRCm39) |
I448V |
probably benign |
Het |
| Anapc5 |
G |
A |
5: 122,956,928 (GRCm39) |
T117M |
probably damaging |
Het |
| Cacna1d |
A |
T |
14: 29,788,120 (GRCm39) |
D1605E |
probably benign |
Het |
| Celsr2 |
C |
T |
3: 108,302,956 (GRCm39) |
G2506R |
probably damaging |
Het |
| Cenpe |
T |
A |
3: 134,948,063 (GRCm39) |
F31L |
possibly damaging |
Het |
| Cenpj |
G |
A |
14: 56,764,501 (GRCm39) |
R1304* |
probably null |
Het |
| Cfap58 |
A |
G |
19: 47,970,561 (GRCm39) |
D593G |
possibly damaging |
Het |
| Crip2 |
T |
C |
12: 113,107,777 (GRCm39) |
|
probably null |
Het |
| Crocc2 |
G |
T |
1: 93,122,311 (GRCm39) |
A735S |
possibly damaging |
Het |
| Dnah2 |
A |
G |
11: 69,439,816 (GRCm39) |
|
probably null |
Het |
| Dpp8 |
C |
T |
9: 64,960,402 (GRCm39) |
T311M |
possibly damaging |
Het |
| Eps15 |
T |
C |
4: 109,186,922 (GRCm39) |
S330P |
probably damaging |
Het |
| Exoc2 |
C |
T |
13: 31,066,255 (GRCm39) |
V474I |
probably benign |
Het |
| Foxn2 |
T |
C |
17: 88,794,311 (GRCm39) |
I416T |
possibly damaging |
Het |
| Gbp8 |
T |
C |
5: 105,178,880 (GRCm39) |
E145G |
probably damaging |
Het |
| Gm3676 |
T |
A |
14: 41,365,233 (GRCm39) |
I141L |
probably benign |
Het |
| Gm4131 |
A |
G |
14: 62,718,538 (GRCm39) |
Y23H |
possibly damaging |
Het |
| Gucy1b1 |
T |
A |
3: 81,947,054 (GRCm39) |
D385V |
possibly damaging |
Het |
| Hdac2 |
T |
C |
10: 36,865,232 (GRCm39) |
S149P |
probably damaging |
Het |
| Hivep3 |
CGG |
CG |
4: 119,955,108 (GRCm39) |
1141 |
probably null |
Het |
| Igsf9b |
A |
T |
9: 27,245,418 (GRCm39) |
R1128S |
probably benign |
Het |
| Invs |
A |
G |
4: 48,392,668 (GRCm39) |
H294R |
probably damaging |
Het |
| Kansl3 |
G |
A |
1: 36,382,876 (GRCm39) |
S812F |
probably damaging |
Het |
| Katnbl1 |
T |
C |
2: 112,239,538 (GRCm39) |
S246P |
probably benign |
Het |
| Kcnt1 |
A |
T |
2: 25,791,358 (GRCm39) |
H567L |
probably benign |
Het |
| Krt33a |
A |
G |
11: 99,902,765 (GRCm39) |
I353T |
probably damaging |
Het |
| Lrguk |
A |
T |
6: 34,078,683 (GRCm39) |
R639S |
possibly damaging |
Het |
| Lrrc37 |
G |
T |
11: 103,507,116 (GRCm39) |
H1617Q |
unknown |
Het |
| Mcoln2 |
A |
T |
3: 145,881,299 (GRCm39) |
|
probably null |
Het |
| Myo15a |
A |
G |
11: 60,395,978 (GRCm39) |
T1438A |
|
Het |
| Myocd |
A |
G |
11: 65,109,429 (GRCm39) |
L114P |
probably damaging |
Het |
| Nutm1 |
T |
C |
2: 112,079,584 (GRCm39) |
N777S |
probably benign |
Het |
| Or5b21 |
A |
T |
19: 12,839,141 (GRCm39) |
M1L |
probably benign |
Het |
| Pde4b |
A |
G |
4: 102,112,503 (GRCm39) |
E29G |
probably damaging |
Het |
| Plekhn1 |
G |
A |
4: 156,309,277 (GRCm39) |
P210S |
probably benign |
Het |
| Por |
G |
T |
5: 135,758,358 (GRCm39) |
A112S |
probably damaging |
Het |
| Prkcq |
T |
C |
2: 11,304,221 (GRCm39) |
F651S |
probably damaging |
Het |
| Rnf148 |
A |
C |
6: 23,654,979 (GRCm39) |
S6A |
probably benign |
Het |
| Selenoi |
A |
G |
5: 30,471,926 (GRCm39) |
I376V |
possibly damaging |
Het |
| Skint6 |
A |
T |
4: 113,034,243 (GRCm39) |
|
probably null |
Het |
| Tdrd6 |
T |
C |
17: 43,938,817 (GRCm39) |
T744A |
probably benign |
Het |
| Tet2 |
T |
A |
3: 133,172,509 (GRCm39) |
T1918S |
possibly damaging |
Het |
| Ttc28 |
C |
A |
5: 111,371,995 (GRCm39) |
L846M |
probably damaging |
Het |
| Ubxn2a |
A |
T |
12: 4,933,832 (GRCm39) |
V193D |
possibly damaging |
Het |
| Umodl1 |
T |
A |
17: 31,207,031 (GRCm39) |
C807* |
probably null |
Het |
| Upf2 |
T |
A |
2: 5,978,347 (GRCm39) |
S404T |
unknown |
Het |
| Urb1 |
CACTTAC |
CAC |
16: 90,569,461 (GRCm39) |
|
probably benign |
Het |
| Usp53 |
A |
T |
3: 122,743,467 (GRCm39) |
S490T |
probably benign |
Het |
| Wscd1 |
T |
C |
11: 71,650,799 (GRCm39) |
L42P |
possibly damaging |
Het |
| Xirp2 |
T |
C |
2: 67,344,842 (GRCm39) |
I2361T |
probably benign |
Het |
|
| Other mutations in Adgrb2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00309:Adgrb2
|
APN |
4 |
129,912,598 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00425:Adgrb2
|
APN |
4 |
129,912,865 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL00490:Adgrb2
|
APN |
4 |
129,905,665 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
IGL00928:Adgrb2
|
APN |
4 |
129,886,096 (GRCm39) |
missense |
probably benign |
|
|
IGL01353:Adgrb2
|
APN |
4 |
129,906,093 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01521:Adgrb2
|
APN |
4 |
129,886,085 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01590:Adgrb2
|
APN |
4 |
129,907,606 (GRCm39) |
splice site |
probably benign |
|
|
IGL01813:Adgrb2
|
APN |
4 |
129,906,359 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01831:Adgrb2
|
APN |
4 |
129,903,187 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01939:Adgrb2
|
APN |
4 |
129,885,925 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01960:Adgrb2
|
APN |
4 |
129,906,177 (GRCm39) |
splice site |
probably benign |
|
|
IGL01993:Adgrb2
|
APN |
4 |
129,912,635 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02646:Adgrb2
|
APN |
4 |
129,913,075 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02655:Adgrb2
|
APN |
4 |
129,885,972 (GRCm39) |
nonsense |
probably null |
|
|
IGL02695:Adgrb2
|
APN |
4 |
129,912,625 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02998:Adgrb2
|
APN |
4 |
129,912,862 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL03372:Adgrb2
|
APN |
4 |
129,911,362 (GRCm39) |
missense |
probably benign |
0.42 |
|
R0098:Adgrb2
|
UTSW |
4 |
129,901,624 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0206:Adgrb2
|
UTSW |
4 |
129,886,352 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0311:Adgrb2
|
UTSW |
4 |
129,910,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0380:Adgrb2
|
UTSW |
4 |
129,901,624 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0382:Adgrb2
|
UTSW |
4 |
129,901,624 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0492:Adgrb2
|
UTSW |
4 |
129,901,624 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0544:Adgrb2
|
UTSW |
4 |
129,911,335 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0965:Adgrb2
|
UTSW |
4 |
129,886,209 (GRCm39) |
small deletion |
probably benign |
|
|
R1458:Adgrb2
|
UTSW |
4 |
129,908,384 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R1601:Adgrb2
|
UTSW |
4 |
129,886,630 (GRCm39) |
missense |
probably benign |
0.43 |
|
R1711:Adgrb2
|
UTSW |
4 |
129,886,417 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1758:Adgrb2
|
UTSW |
4 |
129,905,668 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1783:Adgrb2
|
UTSW |
4 |
129,903,098 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R1827:Adgrb2
|
UTSW |
4 |
129,906,350 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1838:Adgrb2
|
UTSW |
4 |
129,904,024 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1881:Adgrb2
|
UTSW |
4 |
129,904,078 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1888:Adgrb2
|
UTSW |
4 |
129,907,419 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1888:Adgrb2
|
UTSW |
4 |
129,907,419 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1894:Adgrb2
|
UTSW |
4 |
129,907,419 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2275:Adgrb2
|
UTSW |
4 |
129,900,647 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2926:Adgrb2
|
UTSW |
4 |
129,902,137 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4472:Adgrb2
|
UTSW |
4 |
129,902,146 (GRCm39) |
missense |
probably benign |
0.12 |
|
R4490:Adgrb2
|
UTSW |
4 |
129,906,121 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R4499:Adgrb2
|
UTSW |
4 |
129,886,454 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4758:Adgrb2
|
UTSW |
4 |
129,903,143 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4900:Adgrb2
|
UTSW |
4 |
129,907,668 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4904:Adgrb2
|
UTSW |
4 |
129,906,332 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R4922:Adgrb2
|
UTSW |
4 |
129,901,645 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5330:Adgrb2
|
UTSW |
4 |
129,915,995 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5331:Adgrb2
|
UTSW |
4 |
129,915,995 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5550:Adgrb2
|
UTSW |
4 |
129,908,727 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R5995:Adgrb2
|
UTSW |
4 |
129,910,896 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6047:Adgrb2
|
UTSW |
4 |
129,912,498 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6534:Adgrb2
|
UTSW |
4 |
129,916,012 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6565:Adgrb2
|
UTSW |
4 |
129,913,069 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6813:Adgrb2
|
UTSW |
4 |
129,903,284 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6963:Adgrb2
|
UTSW |
4 |
129,908,155 (GRCm39) |
frame shift |
probably null |
|
|
R6966:Adgrb2
|
UTSW |
4 |
129,908,155 (GRCm39) |
frame shift |
probably null |
|
|
R7197:Adgrb2
|
UTSW |
4 |
129,903,315 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7409:Adgrb2
|
UTSW |
4 |
129,912,862 (GRCm39) |
missense |
probably benign |
0.15 |
|
R7451:Adgrb2
|
UTSW |
4 |
129,908,350 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7453:Adgrb2
|
UTSW |
4 |
129,908,430 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7461:Adgrb2
|
UTSW |
4 |
129,915,006 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
R7511:Adgrb2
|
UTSW |
4 |
129,915,904 (GRCm39) |
missense |
probably benign |
|
|
R7729:Adgrb2
|
UTSW |
4 |
129,885,917 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7818:Adgrb2
|
UTSW |
4 |
129,908,762 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R7818:Adgrb2
|
UTSW |
4 |
129,908,353 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8033:Adgrb2
|
UTSW |
4 |
129,912,805 (GRCm39) |
missense |
probably benign |
|
|
R8039:Adgrb2
|
UTSW |
4 |
129,916,061 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8097:Adgrb2
|
UTSW |
4 |
129,901,690 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8256:Adgrb2
|
UTSW |
4 |
129,901,921 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8425:Adgrb2
|
UTSW |
4 |
129,898,850 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R8804:Adgrb2
|
UTSW |
4 |
129,899,212 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9011:Adgrb2
|
UTSW |
4 |
129,916,111 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9018:Adgrb2
|
UTSW |
4 |
129,907,659 (GRCm39) |
missense |
probably benign |
0.34 |
|
R9102:Adgrb2
|
UTSW |
4 |
129,912,802 (GRCm39) |
missense |
probably benign |
0.04 |
|
R9113:Adgrb2
|
UTSW |
4 |
129,910,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9120:Adgrb2
|
UTSW |
4 |
129,906,302 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R9211:Adgrb2
|
UTSW |
4 |
129,886,199 (GRCm39) |
missense |
probably benign |
0.07 |
|
R9267:Adgrb2
|
UTSW |
4 |
129,885,901 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9328:Adgrb2
|
UTSW |
4 |
129,915,363 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9470:Adgrb2
|
UTSW |
4 |
129,903,074 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9608:Adgrb2
|
UTSW |
4 |
129,907,352 (GRCm39) |
missense |
probably damaging |
0.98 |
|
RF020:Adgrb2
|
UTSW |
4 |
129,903,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Adgrb2
|
UTSW |
4 |
129,911,356 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Adgrb2
|
UTSW |
4 |
129,912,912 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1177:Adgrb2
|
UTSW |
4 |
129,905,619 (GRCm39) |
missense |
probably damaging |
0.99 |
|
| Predicted Primers |
PCR Primer
(F):5'- TATGATCCGACATGGTGGGAAC -3'
(R):5'- CAGTAATGGGTGTGAGCCAGAC -3'
Sequencing Primer
(F):5'- TTCACAGCTGAGCCGTGTCTG -3'
(R):5'- CCAGACAGTGGGGTAGATCC -3'
|
| Posted On |
2019-10-24 |
Incidental Mutation