Incidental Mutation 'R7615:Adgb'
| ID |
588856 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Adgb
|
| Ensembl Gene |
ENSMUSG00000050994 |
| Gene Name |
androglobin |
| Synonyms |
9130014G24Rik |
| MMRRC Submission |
045683-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7615 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
10 |
| Chromosomal Location |
10335703-10472326 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 10436010 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Phenylalanine
at position 226
(L226F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000136386
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000132573]
[ENSMUST00000172530]
[ENSMUST00000179956]
[ENSMUST00000208717]
|
| AlphaFold |
G3UZ78 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000132573
AA Change: L226F
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000120422
Gene: ENSMUSG00000050994
AA Change: L226F
| Domain | Start | End | E-Value | Type |
|---|
|
CysPc
|
56 |
655 |
2.7e-2 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000172530
AA Change: L226F
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000134378
Gene: ENSMUSG00000050994
AA Change: L226F
| Domain | Start | End | E-Value | Type |
|---|
|
CysPc
|
56 |
655 |
2.7e-2 |
SMART |
|
IQ
|
904 |
926 |
6.41e0 |
SMART |
|
low complexity region
|
1179 |
1190 |
N/A |
INTRINSIC |
|
low complexity region
|
1318 |
1335 |
N/A |
INTRINSIC |
|
coiled coil region
|
1534 |
1559 |
N/A |
INTRINSIC |
|
low complexity region
|
1616 |
1633 |
N/A |
INTRINSIC |
|
low complexity region
|
1649 |
1657 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000179956
AA Change: L226F
PolyPhen 2
Score 0.960 (Sensitivity: 0.78; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000136386
Gene: ENSMUSG00000050994
AA Change: L226F
| Domain | Start | End | E-Value | Type |
|---|
|
CysPc
|
56 |
657 |
5.36e-2 |
SMART |
|
IQ
|
906 |
928 |
6.41e0 |
SMART |
|
low complexity region
|
1181 |
1192 |
N/A |
INTRINSIC |
|
low complexity region
|
1321 |
1338 |
N/A |
INTRINSIC |
|
coiled coil region
|
1537 |
1562 |
N/A |
INTRINSIC |
|
low complexity region
|
1619 |
1636 |
N/A |
INTRINSIC |
|
low complexity region
|
1652 |
1660 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000208717
AA Change: L220F
PolyPhen 2
Score 0.994 (Sensitivity: 0.69; Specificity: 0.97)
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
100% (101/101) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 100 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4931406B18Rik |
T |
C |
7: 43,497,849 (GRCm38) |
I320V |
possibly damaging |
Het |
| Adat2 |
A |
G |
10: 13,553,276 (GRCm38) |
K4R |
probably benign |
Het |
| Adgrb3 |
C |
T |
1: 25,098,897 (GRCm38) |
V1192I |
probably damaging |
Het |
| Ahsa2 |
T |
A |
11: 23,496,750 (GRCm38) |
N71I |
possibly damaging |
Het |
| Amigo2 |
T |
G |
15: 97,245,342 (GRCm38) |
T400P |
probably damaging |
Het |
| Ankhd1 |
A |
T |
18: 36,656,773 (GRCm38) |
Q466L |
|
Het |
| Auh |
T |
C |
13: 52,919,013 (GRCm38) |
I111V |
probably benign |
Het |
| Brwd1 |
A |
G |
16: 96,033,839 (GRCm38) |
F942L |
probably damaging |
Het |
| C1qtnf7 |
A |
G |
5: 43,616,144 (GRCm38) |
N262D |
probably damaging |
Het |
| Cdh9 |
T |
A |
15: 16,856,230 (GRCm38) |
S785R |
probably damaging |
Het |
| Celsr3 |
A |
G |
9: 108,837,652 (GRCm38) |
T2046A |
possibly damaging |
Het |
| Cep170b |
T |
C |
12: 112,744,665 (GRCm38) |
V1493A |
probably damaging |
Het |
| Cep290 |
C |
T |
10: 100,492,681 (GRCm38) |
R111W |
probably benign |
Het |
| Chd2 |
T |
A |
7: 73,441,642 (GRCm38) |
H1617L |
probably damaging |
Het |
| Ciao3 |
C |
T |
17: 25,782,129 (GRCm38) |
P452S |
probably benign |
Het |
| Clnk |
T |
C |
5: 38,706,698 (GRCm38) |
D404G |
probably damaging |
Het |
| Col18a1 |
C |
T |
10: 77,067,005 (GRCm38) |
G795D |
probably damaging |
Het |
| Csf3r |
T |
A |
4: 126,037,656 (GRCm38) |
Y477* |
probably null |
Het |
| Dnah17 |
T |
A |
11: 118,110,547 (GRCm38) |
K857* |
probably null |
Het |
| Dnah2 |
T |
G |
11: 69,435,304 (GRCm38) |
I3674L |
probably damaging |
Het |
| Dnah6 |
A |
C |
6: 73,095,206 (GRCm38) |
I2431S |
possibly damaging |
Het |
| Eml6 |
T |
A |
11: 29,802,501 (GRCm38) |
I971F |
possibly damaging |
Het |
| Fam135b |
A |
T |
15: 71,463,323 (GRCm38) |
I674N |
probably damaging |
Het |
| Fancc |
T |
A |
13: 63,317,558 (GRCm38) |
|
probably null |
Het |
| Gabrb2 |
A |
C |
11: 42,626,742 (GRCm38) |
K464Q |
probably benign |
Het |
| Gbp4 |
T |
A |
5: 105,122,982 (GRCm38) |
D261V |
possibly damaging |
Het |
| Gdf3 |
A |
G |
6: 122,606,916 (GRCm38) |
V164A |
probably benign |
Het |
| Gm19410 |
A |
G |
8: 35,796,359 (GRCm38) |
D978G |
probably damaging |
Het |
| Gm20730 |
C |
T |
6: 43,081,774 (GRCm38) |
G35R |
probably null |
Het |
| Grin2b |
G |
A |
6: 135,923,364 (GRCm38) |
T173I |
probably damaging |
Het |
| Gtf3c3 |
A |
T |
1: 54,423,572 (GRCm38) |
V344E |
possibly damaging |
Het |
| Hsd3b5 |
A |
G |
3: 98,630,104 (GRCm38) |
I32T |
probably damaging |
Het |
| Ido1 |
G |
C |
8: 24,593,188 (GRCm38) |
L74V |
probably damaging |
Het |
| Igkv1-88 |
T |
A |
6: 68,862,373 (GRCm38) |
D85V |
probably damaging |
Het |
| Il22ra1 |
A |
G |
4: 135,737,459 (GRCm38) |
I159V |
probably benign |
Het |
| Iqgap1 |
A |
G |
7: 80,751,346 (GRCm38) |
V531A |
probably benign |
Het |
| Iqgap1 |
A |
T |
7: 80,730,100 (GRCm38) |
F1175Y |
probably damaging |
Het |
| Itga1 |
T |
A |
13: 114,996,922 (GRCm38) |
Q484L |
probably null |
Het |
| Itga11 |
A |
T |
9: 62,744,018 (GRCm38) |
E281V |
probably benign |
Het |
| Kpna3 |
T |
C |
14: 61,372,962 (GRCm38) |
N343S |
possibly damaging |
Het |
| Larp1b |
A |
G |
3: 41,033,534 (GRCm38) |
K64E |
possibly damaging |
Het |
| Larp1b |
A |
G |
3: 41,035,816 (GRCm38) |
N133S |
probably benign |
Het |
| Lctl |
T |
A |
9: 64,122,110 (GRCm38) |
L161H |
probably damaging |
Het |
| Mlip |
A |
G |
9: 77,230,483 (GRCm38) |
S381P |
probably damaging |
Het |
| Mroh9 |
A |
G |
1: 163,046,032 (GRCm38) |
I518T |
probably benign |
Het |
| Mst1r |
A |
G |
9: 107,920,012 (GRCm38) |
Q1360R |
probably benign |
Het |
| Muc5b |
T |
A |
7: 141,864,892 (GRCm38) |
C3858* |
probably null |
Het |
| Naip1 |
A |
T |
13: 100,425,776 (GRCm38) |
H960Q |
probably benign |
Het |
| Neo1 |
A |
T |
9: 58,884,503 (GRCm38) |
S1321T |
probably benign |
Het |
| Nid2 |
C |
A |
14: 19,802,530 (GRCm38) |
T1102K |
probably damaging |
Het |
| Nsmaf |
C |
T |
4: 6,408,563 (GRCm38) |
V739M |
probably damaging |
Het |
| Or1o2 |
T |
G |
17: 37,231,450 (GRCm38) |
K307Q |
probably benign |
Het |
| Or4k15 |
T |
G |
14: 50,126,989 (GRCm38) |
S137R |
probably benign |
Het |
| Or5ar1 |
T |
A |
2: 85,841,657 (GRCm38) |
M45L |
probably benign |
Het |
| Or5b110-ps1 |
A |
G |
19: 13,282,590 (GRCm38) |
I156T |
probably damaging |
Het |
| Or5d39 |
T |
C |
2: 88,149,518 (GRCm38) |
Q167R |
probably benign |
Het |
| Osbpl9 |
G |
A |
4: 109,086,339 (GRCm38) |
P159S |
probably damaging |
Het |
| Parpbp |
A |
G |
10: 88,093,637 (GRCm38) |
S450P |
probably damaging |
Het |
| Pdgfrb |
A |
G |
18: 61,064,046 (GRCm38) |
T185A |
probably benign |
Het |
| Pkd1 |
T |
C |
17: 24,593,502 (GRCm38) |
V3803A |
probably damaging |
Het |
| Plau |
A |
T |
14: 20,839,466 (GRCm38) |
K200* |
probably null |
Het |
| Plce1 |
A |
T |
19: 38,524,665 (GRCm38) |
Q136L |
probably benign |
Het |
| Plekhd1 |
C |
T |
12: 80,722,445 (GRCm38) |
T493I |
probably benign |
Het |
| Pofut1 |
T |
C |
2: 153,259,418 (GRCm38) |
S31P |
unknown |
Het |
| Prlr |
T |
A |
15: 10,325,924 (GRCm38) |
I243N |
probably damaging |
Het |
| Ptgis |
A |
G |
2: 167,223,988 (GRCm38) |
L174P |
probably damaging |
Het |
| Ralgapb |
T |
A |
2: 158,450,270 (GRCm38) |
I792K |
probably damaging |
Het |
| Retreg3 |
C |
T |
11: 101,102,980 (GRCm38) |
S136N |
probably damaging |
Het |
| Rigi |
T |
A |
4: 40,229,653 (GRCm38) |
I89F |
possibly damaging |
Het |
| Rnf213 |
C |
T |
11: 119,467,297 (GRCm38) |
T4291M |
|
Het |
| Rtn1 |
A |
G |
12: 72,304,143 (GRCm38) |
Y431H |
probably damaging |
Het |
| Rwdd3 |
A |
G |
3: 121,171,604 (GRCm38) |
|
probably benign |
Het |
| Scyl3 |
A |
T |
1: 163,950,338 (GRCm38) |
|
probably null |
Het |
| Sh2b2 |
G |
T |
5: 136,219,657 (GRCm38) |
Q510K |
probably damaging |
Het |
| Sh2b3 |
G |
A |
5: 121,818,700 (GRCm38) |
P333S |
probably benign |
Het |
| Sirpd |
A |
G |
3: 15,320,485 (GRCm38) |
V119A |
probably damaging |
Het |
| Slc27a6 |
A |
T |
18: 58,609,183 (GRCm38) |
N490Y |
probably damaging |
Het |
| Slc45a1 |
C |
T |
4: 150,638,545 (GRCm38) |
R294Q |
probably benign |
Het |
| Sorl1 |
A |
C |
9: 41,977,582 (GRCm38) |
I1974S |
possibly damaging |
Het |
| Specc1l |
C |
A |
10: 75,263,286 (GRCm38) |
N857K |
probably benign |
Het |
| Speg |
T |
C |
1: 75,429,242 (GRCm38) |
L3030P |
probably damaging |
Het |
| Spsb1 |
A |
C |
4: 149,906,900 (GRCm38) |
D70E |
probably benign |
Het |
| Srsf11 |
A |
G |
3: 158,016,425 (GRCm38) |
S270P |
unknown |
Het |
| Ssr3 |
A |
C |
3: 65,387,792 (GRCm38) |
V100G |
probably damaging |
Het |
| Synpo |
G |
A |
18: 60,604,475 (GRCm38) |
T133I |
probably damaging |
Het |
| Tas2r120 |
T |
G |
6: 132,657,810 (GRCm38) |
V285G |
probably benign |
Het |
| Tenm4 |
T |
A |
7: 96,845,926 (GRCm38) |
V1187D |
probably damaging |
Het |
| Tmed8 |
C |
A |
12: 87,181,388 (GRCm38) |
|
probably null |
Het |
| Tmem51 |
G |
A |
4: 142,037,564 (GRCm38) |
T61M |
probably damaging |
Het |
| Tonsl |
A |
T |
15: 76,630,607 (GRCm38) |
D1132E |
probably benign |
Het |
| Tor1aip1 |
C |
T |
1: 156,007,584 (GRCm38) |
V358I |
possibly damaging |
Het |
| Txlna |
A |
T |
4: 129,630,319 (GRCm38) |
M415K |
probably damaging |
Het |
| Tyms |
T |
A |
5: 30,073,560 (GRCm38) |
|
probably benign |
Het |
| Uggt2 |
G |
T |
14: 119,089,269 (GRCm38) |
L177I |
probably benign |
Het |
| Uqcrh |
T |
C |
4: 116,069,879 (GRCm38) |
H74R |
probably benign |
Het |
| Wnk1 |
A |
T |
6: 119,932,738 (GRCm38) |
S33T |
probably benign |
Het |
| Zfp553 |
T |
A |
7: 127,236,016 (GRCm38) |
C248S |
probably damaging |
Het |
| Zfp574 |
G |
A |
7: 25,080,576 (GRCm38) |
C341Y |
possibly damaging |
Het |
| Zfp729b |
T |
C |
13: 67,591,498 (GRCm38) |
T883A |
possibly damaging |
Het |
| Zfp738 |
T |
A |
13: 67,670,203 (GRCm38) |
K556N |
probably damaging |
Het |
|
| Other mutations in Adgb |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00503:Adgb
|
APN |
10 |
10,406,099 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
IGL01083:Adgb
|
APN |
10 |
10,407,554 (GRCm38) |
missense |
possibly damaging |
0.50 |
|
IGL03064:Adgb
|
APN |
10 |
10,400,572 (GRCm38) |
missense |
probably benign |
0.02 |
|
R0080:Adgb
|
UTSW |
10 |
10,377,839 (GRCm38) |
splice site |
probably benign |
|
|
R0084:Adgb
|
UTSW |
10 |
10,396,344 (GRCm38) |
missense |
possibly damaging |
0.74 |
|
R0112:Adgb
|
UTSW |
10 |
10,407,158 (GRCm38) |
splice site |
probably benign |
|
|
R0348:Adgb
|
UTSW |
10 |
10,357,879 (GRCm38) |
missense |
probably benign |
|
|
R0415:Adgb
|
UTSW |
10 |
10,431,067 (GRCm38) |
splice site |
probably null |
|
|
R0633:Adgb
|
UTSW |
10 |
10,391,729 (GRCm38) |
missense |
probably benign |
0.36 |
|
R1052:Adgb
|
UTSW |
10 |
10,442,613 (GRCm38) |
missense |
probably benign |
0.29 |
|
R1248:Adgb
|
UTSW |
10 |
10,395,310 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R1278:Adgb
|
UTSW |
10 |
10,382,828 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1568:Adgb
|
UTSW |
10 |
10,442,665 (GRCm38) |
nonsense |
probably null |
|
|
R1647:Adgb
|
UTSW |
10 |
10,395,371 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1648:Adgb
|
UTSW |
10 |
10,395,371 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1663:Adgb
|
UTSW |
10 |
10,339,675 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R1688:Adgb
|
UTSW |
10 |
10,350,317 (GRCm38) |
nonsense |
probably null |
|
|
R1758:Adgb
|
UTSW |
10 |
10,426,605 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1772:Adgb
|
UTSW |
10 |
10,382,721 (GRCm38) |
splice site |
probably benign |
|
|
R1850:Adgb
|
UTSW |
10 |
10,442,502 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1959:Adgb
|
UTSW |
10 |
10,395,249 (GRCm38) |
missense |
probably benign |
0.02 |
|
R1980:Adgb
|
UTSW |
10 |
10,433,498 (GRCm38) |
missense |
probably benign |
|
|
R2179:Adgb
|
UTSW |
10 |
10,395,274 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R2229:Adgb
|
UTSW |
10 |
10,436,051 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2283:Adgb
|
UTSW |
10 |
10,377,891 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R2870:Adgb
|
UTSW |
10 |
10,431,281 (GRCm38) |
critical splice donor site |
probably null |
|
|
R2870:Adgb
|
UTSW |
10 |
10,431,281 (GRCm38) |
critical splice donor site |
probably null |
|
|
R2875:Adgb
|
UTSW |
10 |
10,422,719 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2876:Adgb
|
UTSW |
10 |
10,422,719 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2920:Adgb
|
UTSW |
10 |
10,390,243 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2931:Adgb
|
UTSW |
10 |
10,442,502 (GRCm38) |
missense |
possibly damaging |
0.84 |
|
R3722:Adgb
|
UTSW |
10 |
10,340,510 (GRCm38) |
missense |
probably benign |
0.32 |
|
R3846:Adgb
|
UTSW |
10 |
10,382,721 (GRCm38) |
splice site |
probably benign |
|
|
R3877:Adgb
|
UTSW |
10 |
10,442,483 (GRCm38) |
critical splice donor site |
probably null |
|
|
R4210:Adgb
|
UTSW |
10 |
10,407,465 (GRCm38) |
missense |
probably benign |
0.06 |
|
R4211:Adgb
|
UTSW |
10 |
10,407,465 (GRCm38) |
missense |
probably benign |
0.06 |
|
R4333:Adgb
|
UTSW |
10 |
10,442,502 (GRCm38) |
missense |
possibly damaging |
0.84 |
|
R4448:Adgb
|
UTSW |
10 |
10,390,825 (GRCm38) |
missense |
probably benign |
0.32 |
|
R4470:Adgb
|
UTSW |
10 |
10,398,951 (GRCm38) |
missense |
probably benign |
0.02 |
|
R4624:Adgb
|
UTSW |
10 |
10,403,004 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4656:Adgb
|
UTSW |
10 |
10,405,306 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4676:Adgb
|
UTSW |
10 |
10,426,710 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4792:Adgb
|
UTSW |
10 |
10,398,903 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R4795:Adgb
|
UTSW |
10 |
10,357,872 (GRCm38) |
missense |
probably benign |
0.01 |
|
R4858:Adgb
|
UTSW |
10 |
10,349,577 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4985:Adgb
|
UTSW |
10 |
10,400,632 (GRCm38) |
missense |
possibly damaging |
0.69 |
|
R5057:Adgb
|
UTSW |
10 |
10,357,978 (GRCm38) |
missense |
probably benign |
0.11 |
|
R5157:Adgb
|
UTSW |
10 |
10,398,966 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5209:Adgb
|
UTSW |
10 |
10,398,937 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
R5339:Adgb
|
UTSW |
10 |
10,442,606 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5376:Adgb
|
UTSW |
10 |
10,346,563 (GRCm38) |
missense |
probably benign |
0.09 |
|
R5426:Adgb
|
UTSW |
10 |
10,350,260 (GRCm38) |
missense |
probably benign |
0.14 |
|
R5516:Adgb
|
UTSW |
10 |
10,431,157 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5554:Adgb
|
UTSW |
10 |
10,340,473 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R5678:Adgb
|
UTSW |
10 |
10,431,326 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R5707:Adgb
|
UTSW |
10 |
10,391,757 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5708:Adgb
|
UTSW |
10 |
10,391,757 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5891:Adgb
|
UTSW |
10 |
10,377,847 (GRCm38) |
nonsense |
probably null |
|
|
R5928:Adgb
|
UTSW |
10 |
10,378,787 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6005:Adgb
|
UTSW |
10 |
10,395,352 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6017:Adgb
|
UTSW |
10 |
10,450,036 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6049:Adgb
|
UTSW |
10 |
10,378,026 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6118:Adgb
|
UTSW |
10 |
10,431,291 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6175:Adgb
|
UTSW |
10 |
10,398,943 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R6186:Adgb
|
UTSW |
10 |
10,422,758 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6234:Adgb
|
UTSW |
10 |
10,353,080 (GRCm38) |
splice site |
probably null |
|
|
R6383:Adgb
|
UTSW |
10 |
10,450,028 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6522:Adgb
|
UTSW |
10 |
10,377,892 (GRCm38) |
nonsense |
probably null |
|
|
R6639:Adgb
|
UTSW |
10 |
10,435,956 (GRCm38) |
missense |
possibly damaging |
0.51 |
|
R6697:Adgb
|
UTSW |
10 |
10,406,126 (GRCm38) |
nonsense |
probably null |
|
|
R6742:Adgb
|
UTSW |
10 |
10,411,849 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6745:Adgb
|
UTSW |
10 |
10,390,197 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6850:Adgb
|
UTSW |
10 |
10,394,574 (GRCm38) |
missense |
probably benign |
0.39 |
|
R7128:Adgb
|
UTSW |
10 |
10,472,241 (GRCm38) |
missense |
probably benign |
0.26 |
|
R7326:Adgb
|
UTSW |
10 |
10,400,574 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
R7386:Adgb
|
UTSW |
10 |
10,377,949 (GRCm38) |
missense |
possibly damaging |
0.52 |
|
R7431:Adgb
|
UTSW |
10 |
10,391,955 (GRCm38) |
splice site |
probably null |
|
|
R7569:Adgb
|
UTSW |
10 |
10,431,252 (GRCm38) |
missense |
probably benign |
|
|
R7579:Adgb
|
UTSW |
10 |
10,410,818 (GRCm38) |
nonsense |
probably null |
|
|
R7582:Adgb
|
UTSW |
10 |
10,390,821 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7692:Adgb
|
UTSW |
10 |
10,411,712 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7774:Adgb
|
UTSW |
10 |
10,339,660 (GRCm38) |
nonsense |
probably null |
|
|
R7808:Adgb
|
UTSW |
10 |
10,378,659 (GRCm38) |
splice site |
probably null |
|
|
R8158:Adgb
|
UTSW |
10 |
10,378,734 (GRCm38) |
missense |
probably benign |
0.22 |
|
R8386:Adgb
|
UTSW |
10 |
10,350,304 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8746:Adgb
|
UTSW |
10 |
10,405,284 (GRCm38) |
critical splice donor site |
probably null |
|
|
R8785:Adgb
|
UTSW |
10 |
10,357,966 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9089:Adgb
|
UTSW |
10 |
10,442,688 (GRCm38) |
missense |
probably benign |
0.26 |
|
R9140:Adgb
|
UTSW |
10 |
10,340,519 (GRCm38) |
nonsense |
probably null |
|
|
R9386:Adgb
|
UTSW |
10 |
10,398,964 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9777:Adgb
|
UTSW |
10 |
10,407,470 (GRCm38) |
missense |
possibly damaging |
0.74 |
|
X0003:Adgb
|
UTSW |
10 |
10,394,630 (GRCm38) |
missense |
possibly damaging |
0.76 |
|
Z1176:Adgb
|
UTSW |
10 |
10,378,742 (GRCm38) |
missense |
probably benign |
0.09 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACCTGTGCTGTGATCACATTAAC -3'
(R):5'- GCATATGTCTGTATCAGCAGTAATC -3'
Sequencing Primer
(F):5'- TTACATTGTGTAGAAGGAAAGATTCC -3'
(R):5'- GCTTCATTTTATGCTCAAAAGGC -3'
|
| Posted On |
2019-10-24 |
Incidental Mutation