Incidental Mutation 'R0233:Arap1'
| ID |
58896 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Arap1
|
| Ensembl Gene |
ENSMUSG00000032812 |
| Gene Name |
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| Synonyms |
Centd2, 2410002L19Rik |
| MMRRC Submission |
038474-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0233 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
7 |
| Chromosomal Location |
100997296-101061793 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 101049448 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Leucine
at position 970
(S970L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000102624
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000084895]
[ENSMUST00000084896]
[ENSMUST00000098243]
[ENSMUST00000107010]
[ENSMUST00000155754]
|
| AlphaFold |
Q4LDD4 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000084895
AA Change: S722L
PolyPhen 2
Score 0.451 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000081957
Gene: ENSMUSG00000032812
AA Change: S722L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
19 |
37 |
N/A |
INTRINSIC |
|
PH
|
82 |
175 |
2.62e-17 |
SMART |
|
PH
|
195 |
285 |
3.6e-6 |
SMART |
|
ArfGap
|
289 |
415 |
2.4e-22 |
SMART |
|
PH
|
498 |
606 |
1.23e-13 |
SMART |
|
PH
|
616 |
710 |
1.08e0 |
SMART |
|
RhoGAP
|
722 |
904 |
1.35e-63 |
SMART |
|
Pfam:RA
|
926 |
1015 |
1.5e-10 |
PFAM |
|
PH
|
1029 |
1141 |
8.58e-13 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000084896
AA Change: S970L
PolyPhen 2
Score 0.471 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000081958
Gene: ENSMUSG00000032812
AA Change: S970L
| Domain | Start | End | E-Value | Type |
|---|
|
SAM
|
3 |
70 |
1.72e-7 |
SMART |
|
low complexity region
|
92 |
104 |
N/A |
INTRINSIC |
|
low complexity region
|
115 |
126 |
N/A |
INTRINSIC |
|
low complexity region
|
135 |
146 |
N/A |
INTRINSIC |
|
low complexity region
|
151 |
167 |
N/A |
INTRINSIC |
|
low complexity region
|
197 |
227 |
N/A |
INTRINSIC |
|
low complexity region
|
267 |
285 |
N/A |
INTRINSIC |
|
PH
|
330 |
423 |
2.62e-17 |
SMART |
|
PH
|
443 |
533 |
3.6e-6 |
SMART |
|
ArfGap
|
537 |
663 |
2.4e-22 |
SMART |
|
PH
|
746 |
854 |
1.23e-13 |
SMART |
|
PH
|
864 |
958 |
1.08e0 |
SMART |
|
RhoGAP
|
970 |
1152 |
1.35e-63 |
SMART |
|
Pfam:RA
|
1174 |
1263 |
6.6e-13 |
PFAM |
|
PH
|
1277 |
1400 |
8e-13 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000098243
AA Change: S256L
PolyPhen 2
Score 0.049 (Sensitivity: 0.94; Specificity: 0.83)
|
| SMART Domains |
Protein: ENSMUSP00000095844
Gene: ENSMUSG00000032812
AA Change: S256L
| Domain | Start | End | E-Value | Type |
|---|
|
PH
|
32 |
140 |
1.23e-13 |
SMART |
|
PH
|
150 |
244 |
1.08e0 |
SMART |
|
RhoGAP
|
256 |
438 |
1.35e-63 |
SMART |
|
Pfam:RA
|
460 |
549 |
1.2e-11 |
PFAM |
|
PH
|
563 |
675 |
8.58e-13 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000107010
AA Change: S970L
PolyPhen 2
Score 0.471 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000102624
Gene: ENSMUSG00000032812
AA Change: S970L
| Domain | Start | End | E-Value | Type |
|---|
|
SAM
|
3 |
70 |
1.72e-7 |
SMART |
|
low complexity region
|
92 |
104 |
N/A |
INTRINSIC |
|
low complexity region
|
115 |
126 |
N/A |
INTRINSIC |
|
low complexity region
|
135 |
146 |
N/A |
INTRINSIC |
|
low complexity region
|
151 |
167 |
N/A |
INTRINSIC |
|
low complexity region
|
197 |
227 |
N/A |
INTRINSIC |
|
low complexity region
|
267 |
285 |
N/A |
INTRINSIC |
|
PH
|
330 |
423 |
2.62e-17 |
SMART |
|
PH
|
443 |
533 |
3.6e-6 |
SMART |
|
ArfGap
|
537 |
663 |
2.4e-22 |
SMART |
|
PH
|
746 |
854 |
1.23e-13 |
SMART |
|
PH
|
864 |
958 |
1.08e0 |
SMART |
|
RhoGAP
|
970 |
1152 |
1.35e-63 |
SMART |
|
Pfam:RA
|
1174 |
1263 |
1.9e-10 |
PFAM |
|
PH
|
1277 |
1389 |
8.58e-13 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000125284
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000153340
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000155754
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000210162
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000156017
|
| Meta Mutation Damage Score |
0.1047 |
| Coding Region Coverage |
- 1x: 99.4%
- 3x: 98.9%
- 10x: 97.6%
- 20x: 95.4%
|
| Validation Efficiency |
99% (93/94) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 91 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 3425401B19Rik |
A |
G |
14: 32,385,330 (GRCm39) |
S212P |
probably benign |
Het |
| A730018C14Rik |
A |
C |
12: 112,381,864 (GRCm39) |
|
noncoding transcript |
Het |
| Acsf3 |
A |
G |
8: 123,507,031 (GRCm39) |
Y108C |
probably damaging |
Het |
| Acsl1 |
A |
G |
8: 46,966,606 (GRCm39) |
|
probably benign |
Het |
| Adad1 |
T |
A |
3: 37,139,097 (GRCm39) |
I389N |
possibly damaging |
Het |
| Ankrd27 |
T |
C |
7: 35,300,985 (GRCm39) |
L95P |
probably damaging |
Het |
| Ano5 |
T |
C |
7: 51,185,218 (GRCm39) |
F46S |
possibly damaging |
Het |
| Ap2a1 |
T |
C |
7: 44,565,397 (GRCm39) |
N114S |
probably damaging |
Het |
| Atad3a |
A |
T |
4: 155,830,524 (GRCm39) |
S525T |
probably damaging |
Het |
| B4galnt1 |
T |
C |
10: 127,006,780 (GRCm39) |
|
probably benign |
Het |
| Bltp1 |
T |
A |
3: 37,002,712 (GRCm39) |
C1552* |
probably null |
Het |
| Cacna2d2 |
A |
T |
9: 107,391,869 (GRCm39) |
I463F |
probably damaging |
Het |
| Casp6 |
T |
A |
3: 129,699,624 (GRCm39) |
N34K |
probably damaging |
Het |
| Ccdc175 |
A |
T |
12: 72,152,650 (GRCm39) |
F752I |
probably benign |
Het |
| Cdhr4 |
A |
G |
9: 107,874,133 (GRCm39) |
I76V |
probably benign |
Het |
| Copa |
T |
C |
1: 171,915,234 (GRCm39) |
|
probably null |
Het |
| Cox11 |
C |
T |
11: 90,535,326 (GRCm39) |
T259I |
probably damaging |
Het |
| Cuzd1 |
C |
A |
7: 130,913,545 (GRCm39) |
K357N |
possibly damaging |
Het |
| Dnah5 |
T |
A |
15: 28,333,216 (GRCm39) |
F2206I |
probably damaging |
Het |
| Dnase2b |
T |
A |
3: 146,288,305 (GRCm39) |
K263N |
probably benign |
Het |
| Dync1h1 |
T |
A |
12: 110,607,414 (GRCm39) |
D2668E |
probably benign |
Het |
| Eno1b |
T |
C |
18: 48,180,806 (GRCm39) |
I328T |
probably benign |
Het |
| Fam124b |
T |
C |
1: 80,190,703 (GRCm39) |
S227G |
probably damaging |
Het |
| Fam13b |
T |
A |
18: 34,581,137 (GRCm39) |
Y675F |
probably damaging |
Het |
| Fgf21 |
T |
A |
7: 45,264,721 (GRCm39) |
M4L |
probably benign |
Het |
| Flg2 |
T |
A |
3: 93,109,104 (GRCm39) |
C377* |
probably null |
Het |
| Foxp2 |
T |
C |
6: 15,409,752 (GRCm39) |
S451P |
probably damaging |
Het |
| Gli2 |
A |
T |
1: 118,763,655 (GRCm39) |
S1499T |
probably damaging |
Het |
| Gm9920 |
A |
T |
15: 54,975,857 (GRCm39) |
|
probably benign |
Het |
| Gpx5 |
T |
A |
13: 21,471,573 (GRCm39) |
D210V |
probably damaging |
Het |
| H2-T5 |
A |
G |
17: 36,478,361 (GRCm39) |
Y224H |
probably benign |
Het |
| Hoxb5 |
T |
A |
11: 96,195,853 (GRCm39) |
S234T |
probably benign |
Het |
| Irf9 |
C |
A |
14: 55,843,551 (GRCm39) |
N140K |
probably benign |
Het |
| Isg20 |
C |
A |
7: 78,566,334 (GRCm39) |
D94E |
probably damaging |
Het |
| Isg20 |
C |
T |
7: 78,564,243 (GRCm39) |
T50M |
probably damaging |
Het |
| Izumo1 |
T |
C |
7: 45,273,592 (GRCm39) |
L115P |
probably damaging |
Het |
| Kdm3b |
G |
A |
18: 34,942,473 (GRCm39) |
E655K |
probably damaging |
Het |
| Kdm5b |
T |
G |
1: 134,532,372 (GRCm39) |
|
probably benign |
Het |
| Kifc3 |
A |
G |
8: 95,828,100 (GRCm39) |
|
probably null |
Het |
| Kpna2 |
T |
C |
11: 106,883,457 (GRCm39) |
S111G |
probably benign |
Het |
| Krt73 |
A |
T |
15: 101,710,451 (GRCm39) |
N94K |
probably benign |
Het |
| Lgmn |
G |
T |
12: 102,366,248 (GRCm39) |
D247E |
probably damaging |
Het |
| Lilra6 |
C |
T |
7: 3,917,935 (GRCm39) |
V70I |
possibly damaging |
Het |
| Lrig3 |
G |
A |
10: 125,849,395 (GRCm39) |
|
probably null |
Het |
| Lrrc4 |
T |
C |
6: 28,829,734 (GRCm39) |
H627R |
probably benign |
Het |
| Macf1 |
G |
A |
4: 123,343,920 (GRCm39) |
|
probably benign |
Het |
| Nat9 |
C |
A |
11: 115,074,234 (GRCm39) |
|
probably null |
Het |
| Nutm2 |
A |
G |
13: 50,621,441 (GRCm39) |
D2G |
probably benign |
Het |
| Or10j3b |
A |
T |
1: 173,043,868 (GRCm39) |
I217F |
probably benign |
Het |
| Or5h23 |
A |
T |
16: 58,906,038 (GRCm39) |
D269E |
probably benign |
Het |
| Or5w8 |
A |
G |
2: 87,688,096 (GRCm39) |
I192M |
probably benign |
Het |
| Parl |
G |
A |
16: 20,106,657 (GRCm39) |
P184L |
probably damaging |
Het |
| Pdzd8 |
A |
T |
19: 59,288,811 (GRCm39) |
M863K |
probably damaging |
Het |
| Phlda3 |
T |
C |
1: 135,694,559 (GRCm39) |
S125P |
probably damaging |
Het |
| Pkd1l3 |
A |
T |
8: 110,377,412 (GRCm39) |
R217* |
probably null |
Het |
| Plekhg5 |
T |
C |
4: 152,196,676 (GRCm39) |
C695R |
probably damaging |
Het |
| Pramel24 |
A |
T |
4: 143,452,633 (GRCm39) |
E21D |
possibly damaging |
Het |
| Prg4 |
T |
C |
1: 150,329,298 (GRCm39) |
|
probably benign |
Het |
| Prkab1 |
A |
G |
5: 116,159,711 (GRCm39) |
|
probably benign |
Het |
| Pyroxd1 |
A |
G |
6: 142,300,356 (GRCm39) |
E162G |
possibly damaging |
Het |
| R3hcc1l |
G |
A |
19: 42,571,360 (GRCm39) |
|
probably null |
Het |
| Rgs12 |
T |
A |
5: 35,187,842 (GRCm39) |
S500T |
probably damaging |
Het |
| Ripor3 |
T |
C |
2: 167,834,518 (GRCm39) |
D299G |
probably damaging |
Het |
| Robo4 |
T |
C |
9: 37,313,977 (GRCm39) |
L76P |
probably damaging |
Het |
| Sbno1 |
T |
C |
5: 124,514,289 (GRCm39) |
Y1302C |
probably damaging |
Het |
| Sec63 |
A |
G |
10: 42,699,904 (GRCm39) |
I655V |
possibly damaging |
Het |
| Serpina11 |
T |
A |
12: 103,946,729 (GRCm39) |
M389L |
probably benign |
Het |
| Sfswap |
C |
A |
5: 129,631,607 (GRCm39) |
P745Q |
possibly damaging |
Het |
| Slc17a3 |
C |
T |
13: 24,039,841 (GRCm39) |
S293F |
probably damaging |
Het |
| Slitrk3 |
C |
T |
3: 72,955,910 (GRCm39) |
S954N |
probably benign |
Het |
| Sorbs2 |
A |
G |
8: 46,222,866 (GRCm39) |
T190A |
probably damaging |
Het |
| Sos2 |
A |
T |
12: 69,664,104 (GRCm39) |
I460N |
probably benign |
Het |
| Spink7 |
T |
A |
18: 62,727,423 (GRCm39) |
I34L |
probably benign |
Het |
| Srbd1 |
A |
G |
17: 86,365,173 (GRCm39) |
S628P |
probably damaging |
Het |
| Srm |
G |
A |
4: 148,677,829 (GRCm39) |
G156S |
probably damaging |
Het |
| Sulf2 |
T |
C |
2: 165,927,589 (GRCm39) |
|
probably benign |
Het |
| Tmc4 |
T |
A |
7: 3,669,866 (GRCm39) |
Y6F |
probably benign |
Het |
| Tmcc2 |
A |
G |
1: 132,288,389 (GRCm39) |
F433L |
probably damaging |
Het |
| Tmprss13 |
T |
G |
9: 45,248,398 (GRCm39) |
|
probably benign |
Het |
| Tnxb |
T |
C |
17: 34,918,007 (GRCm39) |
F2307L |
probably benign |
Het |
| Tsr3 |
A |
G |
17: 25,461,484 (GRCm39) |
E274G |
probably benign |
Het |
| Ttn |
T |
C |
2: 76,725,488 (GRCm39) |
|
probably benign |
Het |
| Tub |
T |
C |
7: 108,628,548 (GRCm39) |
V352A |
possibly damaging |
Het |
| Tubb2a |
A |
G |
13: 34,259,325 (GRCm39) |
I155T |
possibly damaging |
Het |
| Ugt2a2 |
T |
C |
5: 87,622,860 (GRCm39) |
N36S |
probably damaging |
Het |
| Usp13 |
T |
A |
3: 32,969,813 (GRCm39) |
|
probably null |
Het |
| Vmn1r52 |
T |
G |
6: 90,156,593 (GRCm39) |
L120R |
possibly damaging |
Het |
| Vmn2r11 |
A |
T |
5: 109,201,968 (GRCm39) |
S179T |
probably benign |
Het |
| Vwf |
A |
T |
6: 125,663,473 (GRCm39) |
R2805W |
possibly damaging |
Het |
| Wdr7 |
A |
G |
18: 64,037,172 (GRCm39) |
T1199A |
probably benign |
Het |
| Zfp286 |
T |
C |
11: 62,671,219 (GRCm39) |
T285A |
possibly damaging |
Het |
|
| Other mutations in Arap1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00517:Arap1
|
APN |
7 |
101,037,256 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01311:Arap1
|
APN |
7 |
101,037,343 (GRCm39) |
nonsense |
probably null |
|
|
IGL01349:Arap1
|
APN |
7 |
101,036,359 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
IGL01521:Arap1
|
APN |
7 |
101,049,812 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01869:Arap1
|
APN |
7 |
101,049,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02156:Arap1
|
APN |
7 |
101,037,937 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02320:Arap1
|
APN |
7 |
101,034,236 (GRCm39) |
missense |
probably benign |
|
|
IGL02478:Arap1
|
APN |
7 |
101,049,332 (GRCm39) |
splice site |
probably null |
|
|
R0133:Arap1
|
UTSW |
7 |
101,035,436 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0233:Arap1
|
UTSW |
7 |
101,049,448 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R0412:Arap1
|
UTSW |
7 |
101,039,429 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0616:Arap1
|
UTSW |
7 |
101,050,857 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R0838:Arap1
|
UTSW |
7 |
101,049,619 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0962:Arap1
|
UTSW |
7 |
101,034,121 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R1186:Arap1
|
UTSW |
7 |
101,053,476 (GRCm39) |
splice site |
probably benign |
|
|
R1405:Arap1
|
UTSW |
7 |
101,047,643 (GRCm39) |
splice site |
probably null |
|
|
R1405:Arap1
|
UTSW |
7 |
101,047,643 (GRCm39) |
splice site |
probably null |
|
|
R1724:Arap1
|
UTSW |
7 |
101,049,733 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R1793:Arap1
|
UTSW |
7 |
101,037,829 (GRCm39) |
missense |
probably benign |
|
|
R1959:Arap1
|
UTSW |
7 |
101,022,222 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1960:Arap1
|
UTSW |
7 |
101,022,222 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2020:Arap1
|
UTSW |
7 |
101,050,725 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2128:Arap1
|
UTSW |
7 |
101,058,527 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3737:Arap1
|
UTSW |
7 |
101,049,484 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R3851:Arap1
|
UTSW |
7 |
101,039,372 (GRCm39) |
nonsense |
probably null |
|
|
R4034:Arap1
|
UTSW |
7 |
101,049,484 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R4386:Arap1
|
UTSW |
7 |
101,034,778 (GRCm39) |
missense |
probably benign |
|
|
R4435:Arap1
|
UTSW |
7 |
101,039,461 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R4779:Arap1
|
UTSW |
7 |
101,053,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4786:Arap1
|
UTSW |
7 |
101,034,212 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4850:Arap1
|
UTSW |
7 |
101,047,998 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4942:Arap1
|
UTSW |
7 |
101,051,009 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5253:Arap1
|
UTSW |
7 |
101,037,851 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5342:Arap1
|
UTSW |
7 |
101,054,167 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5367:Arap1
|
UTSW |
7 |
101,058,337 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5397:Arap1
|
UTSW |
7 |
101,034,119 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5968:Arap1
|
UTSW |
7 |
101,043,945 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6052:Arap1
|
UTSW |
7 |
101,053,240 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6574:Arap1
|
UTSW |
7 |
101,053,208 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6645:Arap1
|
UTSW |
7 |
101,057,318 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R7060:Arap1
|
UTSW |
7 |
101,058,564 (GRCm39) |
splice site |
probably null |
|
|
R7191:Arap1
|
UTSW |
7 |
101,034,199 (GRCm39) |
missense |
probably benign |
0.31 |
|
R7323:Arap1
|
UTSW |
7 |
101,049,418 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7349:Arap1
|
UTSW |
7 |
101,039,435 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7516:Arap1
|
UTSW |
7 |
101,058,538 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7922:Arap1
|
UTSW |
7 |
101,053,621 (GRCm39) |
nonsense |
probably null |
|
|
R8034:Arap1
|
UTSW |
7 |
101,043,980 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8293:Arap1
|
UTSW |
7 |
101,050,141 (GRCm39) |
missense |
probably benign |
|
|
R8493:Arap1
|
UTSW |
7 |
101,035,725 (GRCm39) |
nonsense |
probably null |
|
|
R8810:Arap1
|
UTSW |
7 |
101,053,585 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8811:Arap1
|
UTSW |
7 |
101,036,403 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8928:Arap1
|
UTSW |
7 |
101,057,324 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R8930:Arap1
|
UTSW |
7 |
101,057,324 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R8931:Arap1
|
UTSW |
7 |
101,057,324 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R8941:Arap1
|
UTSW |
7 |
101,057,324 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R9014:Arap1
|
UTSW |
7 |
101,053,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9144:Arap1
|
UTSW |
7 |
101,047,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9164:Arap1
|
UTSW |
7 |
101,041,090 (GRCm39) |
nonsense |
probably null |
|
|
R9215:Arap1
|
UTSW |
7 |
101,049,214 (GRCm39) |
missense |
probably benign |
0.23 |
|
R9340:Arap1
|
UTSW |
7 |
101,037,382 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9519:Arap1
|
UTSW |
7 |
101,043,946 (GRCm39) |
start gained |
probably benign |
|
|
R9790:Arap1
|
UTSW |
7 |
101,037,376 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9791:Arap1
|
UTSW |
7 |
101,037,376 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CCTTGAAGTACATCTCAGCAGCCC -3'
(R):5'- TGAGTCTTGGAGGTCTGACCACAC -3'
Sequencing Primer
(F):5'- AGTACATCTCAGCAGCCCTTTAG -3'
(R):5'- GAGGTCTGACCACACTTTCGATAG -3'
|
| Posted On |
2013-07-11 |
Incidental Mutation