Mutagenetix > Incidental Mutation

Incidental Mutation 'R7622:Bltp1'

589180

Institutional Source

Beutler Lab

Gene Symbol

Bltp1

Ensembl Gene

ENSMUSG00000037270

Gene Name

bridge-like lipid transfer protein family member 1

Synonyms

FSA, 4932438A13Rik, Tweek

MMRRC Submission

045717-MU

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R7622 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

36863104-37053033 bp(+) (GRCm38)

Type of Mutation

nonsense

DNA Base Change (assembly)

C to A at 36948413 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Cysteine to Stop codon at position 1502 (C1502*)

Ref Sequence

ENSEMBL: ENSMUSP00000060199 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000057272] [ENSMUST00000152564] [ENSMUST00000152881] [ENSMUST00000211820]

AlphaFold

no structure available at present

Predicted Effect

probably null
Transcript: ENSMUST00000057272
AA Change: C1502*

SMART Domains

Protein: ENSMUSP00000060199
Gene: ENSMUSG00000037270
AA Change: C1502*

Domain	Start	End	E-Value	Type
transmembrane domain	25	47	N/A	INTRINSIC
low complexity region	701	716	N/A	INTRINSIC
low complexity region	767	779	N/A	INTRINSIC
low complexity region	1127	1138	N/A	INTRINSIC
low complexity region	1154	1166	N/A	INTRINSIC
low complexity region	1226	1240	N/A	INTRINSIC
low complexity region	1381	1402	N/A	INTRINSIC
low complexity region	1541	1547	N/A	INTRINSIC
low complexity region	1593	1607	N/A	INTRINSIC
low complexity region	1810	1821	N/A	INTRINSIC
low complexity region	1981	1995	N/A	INTRINSIC
low complexity region	2182	2191	N/A	INTRINSIC
low complexity region	2336	2349	N/A	INTRINSIC
low complexity region	2614	2657	N/A	INTRINSIC
low complexity region	3468	3480	N/A	INTRINSIC
low complexity region	3717	3742	N/A	INTRINSIC
low complexity region	3816	3837	N/A	INTRINSIC
low complexity region	3919	3929	N/A	INTRINSIC
low complexity region	3941	3948	N/A	INTRINSIC
low complexity region	4024	4038	N/A	INTRINSIC
low complexity region	4041	4049	N/A	INTRINSIC
low complexity region	4117	4149	N/A	INTRINSIC
low complexity region	4172	4185	N/A	INTRINSIC
low complexity region	4359	4380	N/A	INTRINSIC
FSA_C	4386	4990	N/A	SMART
low complexity region	4993	5004	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000128061

Predicted Effect

probably null
Transcript: ENSMUST00000152564
AA Change: C1502*

SMART Domains

Protein: ENSMUSP00000117808
Gene: ENSMUSG00000037270
AA Change: C1502*

Domain	Start	End	E-Value	Type
transmembrane domain	25	47	N/A	INTRINSIC
low complexity region	701	716	N/A	INTRINSIC
low complexity region	767	779	N/A	INTRINSIC
low complexity region	1127	1138	N/A	INTRINSIC
low complexity region	1154	1166	N/A	INTRINSIC
low complexity region	1226	1240	N/A	INTRINSIC
low complexity region	1381	1402	N/A	INTRINSIC
low complexity region	1541	1547	N/A	INTRINSIC
low complexity region	1593	1607	N/A	INTRINSIC
low complexity region	1810	1821	N/A	INTRINSIC
low complexity region	1981	1995	N/A	INTRINSIC
low complexity region	2182	2191	N/A	INTRINSIC
low complexity region	2336	2349	N/A	INTRINSIC
low complexity region	2614	2657	N/A	INTRINSIC
low complexity region	3468	3480	N/A	INTRINSIC
low complexity region	3717	3742	N/A	INTRINSIC
low complexity region	3816	3837	N/A	INTRINSIC
low complexity region	3919	3929	N/A	INTRINSIC
low complexity region	3941	3948	N/A	INTRINSIC
low complexity region	4024	4038	N/A	INTRINSIC
low complexity region	4041	4049	N/A	INTRINSIC
low complexity region	4117	4149	N/A	INTRINSIC
low complexity region	4172	4185	N/A	INTRINSIC
low complexity region	4359	4380	N/A	INTRINSIC
FSA_C	4386	4990	N/A	SMART
low complexity region	4993	5004	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000152881

SMART Domains

Protein: ENSMUSP00000118366
Gene: ENSMUSG00000037270

Domain	Start	End	E-Value	Type
transmembrane domain	25	47	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000211820
AA Change: C1502*

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.7%
20x: 99.1%

Validation Efficiency

98% (55/56)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene is located on the long arm of chromosome 4 in a region that is associated with susceptibility to celiac disease. The encoded protein is similar to a Chinese hamster protein that is associated with spermatocyte and adipocyte differentiation. The C-terminus of the protein is also similar to a Caenorhabditis elegans protein that plays a role in lipid storage. In mammals, this protein is thought to function in the regulation of epithelial growth and differentiation, and in tumor development. [provided by RefSeq, Oct 2009]

Allele List at MGI

Other mutations in this stock

Total: 56 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adgrd1	G	A	5: 129,139,624 (GRCm38)	D384N	probably benign	Het
Aqp8	T	C	7: 123,466,660 (GRCm38)	F226S	possibly damaging	Het
Arl6ip6	A	G	2: 53,217,327 (GRCm38)	Y207C	probably damaging	Het
Cbfa2t2	A	G	2: 154,500,445 (GRCm38)	E27G	possibly damaging	Het
Cdc42bpb	T	G	12: 111,294,772 (GRCm38)	E201A	unknown	Het
Cfap54	A	C	10: 92,956,944 (GRCm38)	V1769G	unknown	Het
Dmxl2	C	T	9: 54,472,218 (GRCm38)	G7S	probably damaging	Het
Dnah6	G	T	6: 73,124,759 (GRCm38)	F1927L	possibly damaging	Het
Dnajc6	A	G	4: 101,640,491 (GRCm38)	E942G	probably damaging	Het
Fam170a	A	G	18: 50,282,902 (GRCm38)	R324G	probably benign	Het
Gapdhs	G	A	7: 30,739,331 (GRCm38)	T9I	unknown	Het
Gm10320	T	A	13: 98,489,724 (GRCm38)	R51*	probably null	Het
Gm19410	A	T	8: 35,810,347 (GRCm38)	T1776S	possibly damaging	Het
Gm4846	A	T	1: 166,495,872 (GRCm38)	M94K	possibly damaging	Het
Ighv2-5	G	A	12: 113,685,738 (GRCm38)	Q32*	probably null	Het
Klc2	T	C	19: 5,111,632 (GRCm38)	E310G	probably damaging	Het
Krt75	A	G	15: 101,570,272 (GRCm38)	M309T	probably damaging	Het
Lrp11	G	A	10: 7,590,172 (GRCm38)	G41R	unknown	Het
Lrrc52	G	T	1: 167,466,096 (GRCm38)	P207T	probably benign	Het
Lrrc52	G	T	1: 167,466,095 (GRCm38)	P207Q	probably benign	Het
Lrrk2	A	T	15: 91,812,323 (GRCm38)	D2438V	probably damaging	Het
Mycbp	C	T	4: 123,905,301 (GRCm38)	T28M	probably damaging	Het
Myh14	A	G	7: 44,632,422 (GRCm38)	V804A	probably benign	Het
Myo16	A	G	8: 10,376,238 (GRCm38)	I332V	unknown	Het
Ncor1	G	T	11: 62,317,968 (GRCm38)	Q1359K	probably benign	Het
Olfr548-ps1	A	G	7: 102,542,623 (GRCm38)	H229R	probably benign	Het
Oog3	T	C	4: 144,158,319 (GRCm38)	D349G	probably benign	Het
Or12e1	A	T	2: 87,192,250 (GRCm38)	I188L	probably benign	Het
Or1j21	A	G	2: 36,793,931 (GRCm38)	K232E	probably benign	Het
Or8k53	A	G	2: 86,347,662 (GRCm38)	Y35H	possibly damaging	Het
Pate4	A	G	9: 35,608,299 (GRCm38)	S32P	possibly damaging	Het
Pcdhb7	A	C	18: 37,342,461 (GRCm38)	S217R	probably benign	Het
Pde1c	G	A	6: 56,126,925 (GRCm38)	R580C	probably damaging	Het
Pi4ka	C	A	16: 17,293,977 (GRCm38)	A1545S		Het
Pign	G	T	1: 105,648,117 (GRCm38)	T266K	possibly damaging	Het
Pitpnm2	A	G	5: 124,122,027 (GRCm38)	I1134T	probably benign	Het
Ppfia2	G	A	10: 106,830,659 (GRCm38)	V409I	possibly damaging	Het
Prr7	A	G	13: 55,472,796 (GRCm38)	T206A	probably benign	Het
Rnf13	A	T	3: 57,820,534 (GRCm38)	R212*	probably null	Het
Rwdd2b	T	C	16: 87,434,612 (GRCm38)	N218S	probably benign	Het
Serpina3m	A	G	12: 104,389,575 (GRCm38)	D167G	possibly damaging	Het
Slit2	A	T	5: 47,985,205 (GRCm38)	N56Y	probably damaging	Het
Sprr3	G	T	3: 92,457,285 (GRCm38)	T84K	probably damaging	Het
Stab2	A	T	10: 86,873,902 (GRCm38)	H1626Q	possibly damaging	Het
Tex2	C	A	11: 106,546,895 (GRCm38)	D650Y	unknown	Het
Tmprss6	A	G	15: 78,446,726 (GRCm38)	S436P	probably benign	Het
Uba2	A	C	7: 34,165,435 (GRCm38)	F63L	probably damaging	Het
Ubxn2b	C	T	4: 6,214,692 (GRCm38)	S242L	probably damaging	Het
Vmn1r86	T	G	7: 13,102,758 (GRCm38)	I64L	probably benign	Het
Vmn2r67	A	T	7: 85,136,454 (GRCm38)	V781E	probably damaging	Het
Vmn2r80	T	A	10: 79,194,263 (GRCm38)	F641Y	probably damaging	Het
Wdfy4	A	T	14: 33,078,274 (GRCm38)	I1965K		Het
Wdr25	G	A	12: 108,992,893 (GRCm38)	G344S	possibly damaging	Het
Wdr90	G	T	17: 25,854,109 (GRCm38)	F837L	probably benign	Het
Xpo4	A	G	14: 57,597,011 (GRCm38)	V704A	possibly damaging	Het
Zc3h12d	A	G	10: 7,867,269 (GRCm38)	K268E	probably damaging	Het

Other mutations in Bltp1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00428:Bltp1	APN	3	37,011,727 (GRCm38)	missense	probably benign	0.00
IGL00434:Bltp1	APN	3	36,987,299 (GRCm38)	missense	probably damaging	0.98
IGL00640:Bltp1	APN	3	36,908,218 (GRCm38)	missense	probably damaging	1.00
IGL00693:Bltp1	APN	3	37,052,547 (GRCm38)	utr 3 prime	probably benign
IGL00721:Bltp1	APN	3	37,030,751 (GRCm38)	splice site	probably null
IGL00756:Bltp1	APN	3	36,908,218 (GRCm38)	missense	probably damaging	1.00
IGL00896:Bltp1	APN	3	37,039,462 (GRCm38)	missense	probably benign
IGL00902:Bltp1	APN	3	37,041,345 (GRCm38)	missense	probably damaging	1.00
IGL00980:Bltp1	APN	3	37,000,041 (GRCm38)	missense	probably damaging	1.00
IGL01019:Bltp1	APN	3	37,006,984 (GRCm38)	critical splice acceptor site	probably null
IGL01025:Bltp1	APN	3	37,046,280 (GRCm38)	missense	possibly damaging	0.89
IGL01306:Bltp1	APN	3	37,005,013 (GRCm38)	splice site	probably benign
IGL01370:Bltp1	APN	3	36,947,755 (GRCm38)	missense	probably benign	0.07
IGL01377:Bltp1	APN	3	36,973,452 (GRCm38)	critical splice donor site	probably null
IGL01401:Bltp1	APN	3	36,942,292 (GRCm38)	missense	probably benign
IGL01419:Bltp1	APN	3	37,048,121 (GRCm38)	missense	probably damaging	1.00
IGL01432:Bltp1	APN	3	37,003,759 (GRCm38)	missense	possibly damaging	0.87
IGL01433:Bltp1	APN	3	36,887,770 (GRCm38)	missense	probably damaging	1.00
IGL01452:Bltp1	APN	3	36,996,308 (GRCm38)	unclassified	probably benign
IGL01520:Bltp1	APN	3	36,973,260 (GRCm38)	nonsense	probably null
IGL01524:Bltp1	APN	3	36,942,382 (GRCm38)	missense	possibly damaging	0.90
IGL01628:Bltp1	APN	3	37,008,485 (GRCm38)	missense	probably damaging	1.00
IGL01638:Bltp1	APN	3	36,974,311 (GRCm38)	missense	probably damaging	1.00
IGL01650:Bltp1	APN	3	36,992,673 (GRCm38)	splice site	probably benign
IGL01717:Bltp1	APN	3	37,034,736 (GRCm38)	missense	probably benign
IGL01767:Bltp1	APN	3	37,041,363 (GRCm38)	missense	probably benign	0.29
IGL01813:Bltp1	APN	3	36,928,520 (GRCm38)	missense	possibly damaging	0.90
IGL01998:Bltp1	APN	3	36,957,016 (GRCm38)	missense	possibly damaging	0.49
IGL02172:Bltp1	APN	3	37,004,873 (GRCm38)	missense	probably damaging	0.99
IGL02197:Bltp1	APN	3	36,906,735 (GRCm38)	missense	probably damaging	1.00
IGL02248:Bltp1	APN	3	36,969,290 (GRCm38)	critical splice donor site	probably null
IGL02273:Bltp1	APN	3	36,921,437 (GRCm38)	splice site	probably benign
IGL02403:Bltp1	APN	3	37,030,664 (GRCm38)	missense	probably benign
IGL02492:Bltp1	APN	3	37,048,113 (GRCm38)	missense	probably benign	0.04
IGL02517:Bltp1	APN	3	36,958,868 (GRCm38)	missense	probably damaging	1.00
IGL02519:Bltp1	APN	3	36,895,315 (GRCm38)	missense	probably damaging	1.00
IGL02586:Bltp1	APN	3	37,044,608 (GRCm38)	nonsense	probably null
IGL02620:Bltp1	APN	3	37,035,945 (GRCm38)	missense	possibly damaging	0.95
IGL02621:Bltp1	APN	3	37,041,484 (GRCm38)	splice site	probably benign
IGL02670:Bltp1	APN	3	36,967,305 (GRCm38)	nonsense	probably null
IGL02806:Bltp1	APN	3	36,946,494 (GRCm38)	missense	possibly damaging	0.95
IGL02985:Bltp1	APN	3	36,958,757 (GRCm38)	missense	probably damaging	0.99
IGL03004:Bltp1	APN	3	36,965,677 (GRCm38)	splice site	probably benign
IGL03037:Bltp1	APN	3	36,969,207 (GRCm38)	missense	probably benign	0.23
IGL03037:Bltp1	APN	3	36,969,208 (GRCm38)	missense	probably damaging	1.00
IGL03062:Bltp1	APN	3	37,038,517 (GRCm38)	splice site	probably benign
IGL03137:Bltp1	APN	3	37,034,602 (GRCm38)	missense	probably damaging	0.98
IGL03150:Bltp1	APN	3	36,948,066 (GRCm38)	missense	probably damaging	1.00
IGL03204:Bltp1	APN	3	37,050,934 (GRCm38)	splice site	probably benign
IGL03207:Bltp1	APN	3	36,949,996 (GRCm38)	missense	possibly damaging	0.73
IGL03256:Bltp1	APN	3	36,906,683 (GRCm38)	splice site	probably benign
IGL03264:Bltp1	APN	3	37,002,635 (GRCm38)	missense	probably damaging	1.00
IGL03265:Bltp1	APN	3	37,047,991 (GRCm38)	missense	probably benign	0.00
IGL03303:Bltp1	APN	3	36,870,077 (GRCm38)	missense	possibly damaging	0.90
admonished	UTSW	3	36,948,304 (GRCm38)	missense	probably damaging	1.00
alerted	UTSW	3	37,033,265 (GRCm38)	missense	possibly damaging	0.85
informed	UTSW	3	36,965,849 (GRCm38)	missense	probably damaging	1.00
resolved	UTSW	3	36,921,221 (GRCm38)	missense	possibly damaging	0.60
tipped	UTSW	3	36,988,085 (GRCm38)	missense	possibly damaging	0.81
warned	UTSW	3	36,965,621 (GRCm38)	missense	probably damaging	1.00
FR4340:Bltp1	UTSW	3	37,050,752 (GRCm38)	critical splice acceptor site	probably benign
FR4737:Bltp1	UTSW	3	37,050,754 (GRCm38)	critical splice acceptor site	probably benign
PIT4515001:Bltp1	UTSW	3	36,974,236 (GRCm38)	missense	probably damaging	1.00
R0035:Bltp1	UTSW	3	36,987,598 (GRCm38)	nonsense	probably null
R0047:Bltp1	UTSW	3	36,908,192 (GRCm38)	missense	possibly damaging	0.83
R0047:Bltp1	UTSW	3	36,908,192 (GRCm38)	missense	possibly damaging	0.83
R0068:Bltp1	UTSW	3	36,952,221 (GRCm38)	missense	probably benign	0.28
R0068:Bltp1	UTSW	3	36,952,221 (GRCm38)	missense	probably benign	0.28
R0092:Bltp1	UTSW	3	37,028,159 (GRCm38)	missense	probably benign	0.41
R0233:Bltp1	UTSW	3	36,948,563 (GRCm38)	nonsense	probably null
R0233:Bltp1	UTSW	3	36,948,563 (GRCm38)	nonsense	probably null
R0256:Bltp1	UTSW	3	36,917,773 (GRCm38)	missense	probably benign	0.01
R0277:Bltp1	UTSW	3	36,943,182 (GRCm38)	nonsense	probably null
R0321:Bltp1	UTSW	3	36,906,788 (GRCm38)	splice site	probably null
R0323:Bltp1	UTSW	3	36,943,182 (GRCm38)	nonsense	probably null
R0335:Bltp1	UTSW	3	36,969,152 (GRCm38)	missense	probably damaging	1.00
R0375:Bltp1	UTSW	3	37,046,252 (GRCm38)	missense	probably damaging	0.99
R0437:Bltp1	UTSW	3	36,989,804 (GRCm38)	missense	possibly damaging	0.81
R0445:Bltp1	UTSW	3	37,000,065 (GRCm38)	missense	probably damaging	0.99
R0496:Bltp1	UTSW	3	36,987,635 (GRCm38)	missense	probably damaging	1.00
R0531:Bltp1	UTSW	3	37,036,825 (GRCm38)	missense	probably damaging	1.00
R0543:Bltp1	UTSW	3	36,996,458 (GRCm38)	missense	probably benign	0.22
R0545:Bltp1	UTSW	3	36,987,690 (GRCm38)	splice site	probably benign
R0674:Bltp1	UTSW	3	37,044,626 (GRCm38)	missense	possibly damaging	0.86
R0745:Bltp1	UTSW	3	36,928,463 (GRCm38)	missense	probably damaging	1.00
R0755:Bltp1	UTSW	3	36,946,364 (GRCm38)	missense	probably damaging	1.00
R0785:Bltp1	UTSW	3	36,959,334 (GRCm38)	splice site	probably benign
R1056:Bltp1	UTSW	3	37,044,680 (GRCm38)	missense	probably benign	0.44
R1056:Bltp1	UTSW	3	36,983,453 (GRCm38)	missense	possibly damaging	0.69
R1080:Bltp1	UTSW	3	36,988,255 (GRCm38)	missense	probably damaging	1.00
R1103:Bltp1	UTSW	3	36,996,523 (GRCm38)	missense	probably benign
R1119:Bltp1	UTSW	3	36,987,045 (GRCm38)	missense	probably damaging	1.00
R1170:Bltp1	UTSW	3	37,044,631 (GRCm38)	missense	probably damaging	0.98
R1183:Bltp1	UTSW	3	36,895,303 (GRCm38)	missense	possibly damaging	0.51
R1186:Bltp1	UTSW	3	36,996,312 (GRCm38)	unclassified	probably benign
R1201:Bltp1	UTSW	3	36,948,375 (GRCm38)	missense	probably benign
R1219:Bltp1	UTSW	3	36,946,470 (GRCm38)	nonsense	probably null
R1270:Bltp1	UTSW	3	36,952,184 (GRCm38)	missense	probably damaging	1.00
R1273:Bltp1	UTSW	3	36,987,210 (GRCm38)	missense	probably damaging	1.00
R1338:Bltp1	UTSW	3	37,052,535 (GRCm38)	missense	unknown
R1364:Bltp1	UTSW	3	36,987,030 (GRCm38)	missense	probably damaging	1.00
R1437:Bltp1	UTSW	3	36,942,429 (GRCm38)	missense	possibly damaging	0.65
R1447:Bltp1	UTSW	3	36,965,586 (GRCm38)	missense	probably damaging	0.98
R1467:Bltp1	UTSW	3	37,035,945 (GRCm38)	missense	probably damaging	0.99
R1467:Bltp1	UTSW	3	37,035,945 (GRCm38)	missense	probably damaging	0.99
R1470:Bltp1	UTSW	3	36,998,331 (GRCm38)	missense	probably benign	0.31
R1470:Bltp1	UTSW	3	36,998,331 (GRCm38)	missense	probably benign	0.31
R1481:Bltp1	UTSW	3	37,008,434 (GRCm38)	missense	probably damaging	0.99
R1528:Bltp1	UTSW	3	37,052,535 (GRCm38)	missense	unknown
R1533:Bltp1	UTSW	3	37,041,375 (GRCm38)	missense	probably damaging	1.00
R1546:Bltp1	UTSW	3	36,870,056 (GRCm38)	missense	possibly damaging	0.64
R1606:Bltp1	UTSW	3	36,942,399 (GRCm38)	missense	probably damaging	1.00
R1638:Bltp1	UTSW	3	37,035,812 (GRCm38)	nonsense	probably null
R1772:Bltp1	UTSW	3	36,959,432 (GRCm38)	missense	probably damaging	1.00
R1896:Bltp1	UTSW	3	36,908,231 (GRCm38)	nonsense	probably null
R1919:Bltp1	UTSW	3	37,006,983 (GRCm38)	critical splice acceptor site	probably null
R1983:Bltp1	UTSW	3	36,887,865 (GRCm38)	missense	probably null	1.00
R1987:Bltp1	UTSW	3	36,953,985 (GRCm38)	critical splice donor site	probably null
R1992:Bltp1	UTSW	3	37,000,032 (GRCm38)	missense	probably benign	0.32
R1999:Bltp1	UTSW	3	36,908,211 (GRCm38)	missense	probably damaging	1.00
R2004:Bltp1	UTSW	3	36,895,378 (GRCm38)	missense	possibly damaging	0.77
R2010:Bltp1	UTSW	3	36,928,551 (GRCm38)	missense	probably benign	0.09
R2027:Bltp1	UTSW	3	37,047,961 (GRCm38)	splice site	probably benign
R2039:Bltp1	UTSW	3	37,003,878 (GRCm38)	missense	possibly damaging	0.66
R2054:Bltp1	UTSW	3	36,947,853 (GRCm38)	missense	probably benign	0.01
R2089:Bltp1	UTSW	3	36,988,256 (GRCm38)	missense	probably damaging	1.00
R2091:Bltp1	UTSW	3	36,988,256 (GRCm38)	missense	probably damaging	1.00
R2091:Bltp1	UTSW	3	36,988,256 (GRCm38)	missense	probably damaging	1.00
R2091:Bltp1	UTSW	3	36,953,970 (GRCm38)	missense	probably damaging	1.00
R2220:Bltp1	UTSW	3	36,875,530 (GRCm38)	critical splice donor site	probably null
R2374:Bltp1	UTSW	3	36,885,396 (GRCm38)	missense	probably benign	0.00
R2437:Bltp1	UTSW	3	36,958,685 (GRCm38)	splice site	probably null
R2860:Bltp1	UTSW	3	36,965,849 (GRCm38)	missense	probably damaging	1.00
R2861:Bltp1	UTSW	3	36,965,849 (GRCm38)	missense	probably damaging	1.00
R2909:Bltp1	UTSW	3	36,947,953 (GRCm38)	missense	probably damaging	1.00
R2925:Bltp1	UTSW	3	37,007,122 (GRCm38)	missense	probably damaging	0.99
R2940:Bltp1	UTSW	3	36,958,805 (GRCm38)	missense	probably damaging	1.00
R3015:Bltp1	UTSW	3	36,875,462 (GRCm38)	missense	probably damaging	1.00
R3086:Bltp1	UTSW	3	37,011,703 (GRCm38)	missense	possibly damaging	0.56
R3159:Bltp1	UTSW	3	36,959,415 (GRCm38)	missense	probably benign	0.17
R3440:Bltp1	UTSW	3	37,041,912 (GRCm38)	nonsense	probably null
R3703:Bltp1	UTSW	3	36,987,581 (GRCm38)	missense	probably damaging	1.00
R3705:Bltp1	UTSW	3	36,987,581 (GRCm38)	missense	probably damaging	1.00
R3795:Bltp1	UTSW	3	37,030,565 (GRCm38)	missense	probably benign	0.30
R3820:Bltp1	UTSW	3	37,040,434 (GRCm38)	missense	probably damaging	1.00
R3862:Bltp1	UTSW	3	36,885,398 (GRCm38)	missense	possibly damaging	0.73
R3944:Bltp1	UTSW	3	37,030,061 (GRCm38)	missense	possibly damaging	0.90
R4020:Bltp1	UTSW	3	37,012,575 (GRCm38)	intron	probably benign
R4091:Bltp1	UTSW	3	37,030,589 (GRCm38)	missense	probably benign	0.00
R4159:Bltp1	UTSW	3	36,931,083 (GRCm38)	missense	probably benign	0.00
R4231:Bltp1	UTSW	3	36,920,236 (GRCm38)	missense	probably benign	0.10
R4368:Bltp1	UTSW	3	36,988,147 (GRCm38)	nonsense	probably null
R4413:Bltp1	UTSW	3	36,958,681 (GRCm38)	splice site	probably null
R4475:Bltp1	UTSW	3	37,040,395 (GRCm38)	missense	probably damaging	1.00
R4488:Bltp1	UTSW	3	37,003,933 (GRCm38)	missense	probably null	0.93
R4489:Bltp1	UTSW	3	37,003,933 (GRCm38)	missense	probably null	0.93
R4516:Bltp1	UTSW	3	36,895,311 (GRCm38)	missense	possibly damaging	0.90
R4580:Bltp1	UTSW	3	37,030,025 (GRCm38)	missense	probably benign	0.02
R4672:Bltp1	UTSW	3	36,889,990 (GRCm38)	makesense	probably null
R4705:Bltp1	UTSW	3	37,041,889 (GRCm38)	missense	probably benign	0.03
R4735:Bltp1	UTSW	3	37,004,967 (GRCm38)	missense	possibly damaging	0.84
R4741:Bltp1	UTSW	3	36,942,375 (GRCm38)	missense	probably damaging	0.99
R4754:Bltp1	UTSW	3	37,022,466 (GRCm38)	nonsense	probably null
R4778:Bltp1	UTSW	3	36,937,065 (GRCm38)	missense	possibly damaging	0.90
R4833:Bltp1	UTSW	3	36,964,968 (GRCm38)	missense	probably damaging	0.96
R4896:Bltp1	UTSW	3	36,965,937 (GRCm38)	missense	probably damaging	1.00
R4910:Bltp1	UTSW	3	36,998,199 (GRCm38)	missense	probably damaging	1.00
R4922:Bltp1	UTSW	3	36,987,165 (GRCm38)	missense	probably damaging	1.00
R4941:Bltp1	UTSW	3	36,919,901 (GRCm38)	missense	probably benign	0.41
R4941:Bltp1	UTSW	3	36,917,702 (GRCm38)	missense	probably damaging	1.00
R4980:Bltp1	UTSW	3	36,943,312 (GRCm38)	missense	probably damaging	1.00
R5030:Bltp1	UTSW	3	36,943,399 (GRCm38)	intron	probably benign
R5049:Bltp1	UTSW	3	37,041,390 (GRCm38)	missense	probably damaging	1.00
R5049:Bltp1	UTSW	3	37,040,506 (GRCm38)	intron	probably benign
R5089:Bltp1	UTSW	3	36,987,502 (GRCm38)	missense	probably benign	0.02
R5092:Bltp1	UTSW	3	37,000,085 (GRCm38)	missense	probably benign	0.14
R5122:Bltp1	UTSW	3	37,034,757 (GRCm38)	splice site	probably null
R5210:Bltp1	UTSW	3	37,033,265 (GRCm38)	missense	possibly damaging	0.85
R5246:Bltp1	UTSW	3	37,048,050 (GRCm38)	missense	probably damaging	1.00
R5289:Bltp1	UTSW	3	37,000,109 (GRCm38)	missense	probably damaging	0.97
R5348:Bltp1	UTSW	3	37,048,146 (GRCm38)	missense	probably damaging	1.00
R5394:Bltp1	UTSW	3	36,917,668 (GRCm38)	missense	probably damaging	1.00
R5434:Bltp1	UTSW	3	36,875,516 (GRCm38)	missense	probably damaging	1.00
R5667:Bltp1	UTSW	3	36,917,677 (GRCm38)	missense	probably benign	0.00
R5686:Bltp1	UTSW	3	36,917,660 (GRCm38)	missense	probably benign	0.00
R5701:Bltp1	UTSW	3	36,921,360 (GRCm38)	missense	probably benign	0.10
R5778:Bltp1	UTSW	3	36,958,714 (GRCm38)	missense	probably damaging	1.00
R5787:Bltp1	UTSW	3	36,992,733 (GRCm38)	splice site	probably null
R5800:Bltp1	UTSW	3	37,052,443 (GRCm38)	missense	probably damaging	1.00
R5819:Bltp1	UTSW	3	37,048,600 (GRCm38)	missense	probably benign	0.12
R5820:Bltp1	UTSW	3	37,039,526 (GRCm38)	missense	probably benign	0.00
R5952:Bltp1	UTSW	3	36,965,621 (GRCm38)	missense	probably damaging	1.00
R5975:Bltp1	UTSW	3	36,969,221 (GRCm38)	missense	possibly damaging	0.64
R5996:Bltp1	UTSW	3	36,931,116 (GRCm38)	missense	probably benign	0.07
R6192:Bltp1	UTSW	3	36,988,169 (GRCm38)	missense	probably benign	0.00
R6225:Bltp1	UTSW	3	36,948,304 (GRCm38)	missense	probably damaging	1.00
R6234:Bltp1	UTSW	3	36,983,471 (GRCm38)	missense	probably benign	0.00
R6244:Bltp1	UTSW	3	36,956,999 (GRCm38)	missense	probably benign
R6263:Bltp1	UTSW	3	36,931,111 (GRCm38)	missense	probably benign	0.06
R6351:Bltp1	UTSW	3	36,908,228 (GRCm38)	missense	probably damaging	1.00
R6380:Bltp1	UTSW	3	37,033,307 (GRCm38)	missense	probably benign	0.19
R6468:Bltp1	UTSW	3	37,008,443 (GRCm38)	missense	probably damaging	1.00
R6759:Bltp1	UTSW	3	36,988,085 (GRCm38)	missense	possibly damaging	0.81
R6792:Bltp1	UTSW	3	37,011,566 (GRCm38)	critical splice acceptor site	probably null
R6809:Bltp1	UTSW	3	36,874,282 (GRCm38)	missense	probably damaging	0.98
R6841:Bltp1	UTSW	3	37,021,481 (GRCm38)	missense	probably damaging	1.00
R6959:Bltp1	UTSW	3	36,967,189 (GRCm38)	missense	probably damaging	1.00
R7102:Bltp1	UTSW	3	36,940,798 (GRCm38)	missense	probably damaging	0.99
R7188:Bltp1	UTSW	3	36,950,013 (GRCm38)	missense	probably benign	0.06
R7212:Bltp1	UTSW	3	37,048,009 (GRCm38)	missense
R7425:Bltp1	UTSW	3	36,983,394 (GRCm38)	missense	probably benign	0.02
R7425:Bltp1	UTSW	3	36,948,341 (GRCm38)	missense	probably benign
R7451:Bltp1	UTSW	3	37,022,807 (GRCm38)	splice site	probably null
R7604:Bltp1	UTSW	3	36,949,843 (GRCm38)	splice site	probably null
R7671:Bltp1	UTSW	3	36,943,231 (GRCm38)	missense	probably damaging	0.99
R7699:Bltp1	UTSW	3	37,026,154 (GRCm38)	missense	probably benign	0.00
R7699:Bltp1	UTSW	3	36,974,172 (GRCm38)	missense	possibly damaging	0.67
R7700:Bltp1	UTSW	3	36,974,172 (GRCm38)	missense	possibly damaging	0.67
R7700:Bltp1	UTSW	3	37,026,154 (GRCm38)	missense	probably benign	0.00
R7748:Bltp1	UTSW	3	36,959,335 (GRCm38)	critical splice acceptor site	probably null
R7767:Bltp1	UTSW	3	36,920,287 (GRCm38)	critical splice donor site	probably null
R7787:Bltp1	UTSW	3	36,885,408 (GRCm38)	missense	probably damaging	1.00
R7830:Bltp1	UTSW	3	36,964,932 (GRCm38)	frame shift	probably null
R7849:Bltp1	UTSW	3	37,026,328 (GRCm38)	missense
R7912:Bltp1	UTSW	3	37,007,069 (GRCm38)	missense	probably damaging	0.99
R7914:Bltp1	UTSW	3	36,946,283 (GRCm38)	missense	probably benign	0.13
R7945:Bltp1	UTSW	3	36,965,893 (GRCm38)	missense	probably benign	0.03
R8039:Bltp1	UTSW	3	36,943,214 (GRCm38)	missense	probably benign	0.12
R8101:Bltp1	UTSW	3	37,008,502 (GRCm38)	missense	probably damaging	1.00
R8143:Bltp1	UTSW	3	36,946,508 (GRCm38)	critical splice donor site	probably null
R8145:Bltp1	UTSW	3	36,998,267 (GRCm38)	missense	probably damaging	1.00
R8171:Bltp1	UTSW	3	36,975,713 (GRCm38)	missense	probably benign	0.00
R8210:Bltp1	UTSW	3	37,012,881 (GRCm38)	missense
R8250:Bltp1	UTSW	3	36,917,662 (GRCm38)	missense	probably damaging	0.99
R8369:Bltp1	UTSW	3	37,011,603 (GRCm38)	missense
R8478:Bltp1	UTSW	3	37,033,277 (GRCm38)	missense	possibly damaging	0.74
R8558:Bltp1	UTSW	3	37,048,601 (GRCm38)	missense
R8688:Bltp1	UTSW	3	37,035,917 (GRCm38)	missense
R8724:Bltp1	UTSW	3	36,890,893 (GRCm38)	missense	probably damaging	0.99
R8818:Bltp1	UTSW	3	36,996,548 (GRCm38)	missense	possibly damaging	0.60
R8869:Bltp1	UTSW	3	36,958,858 (GRCm38)	missense	probably damaging	0.99
R8887:Bltp1	UTSW	3	37,033,354 (GRCm38)	missense	possibly damaging	0.95
R8899:Bltp1	UTSW	3	36,988,280 (GRCm38)	missense	probably damaging	1.00
R8907:Bltp1	UTSW	3	36,948,146 (GRCm38)	nonsense	probably null
R8960:Bltp1	UTSW	3	37,012,983 (GRCm38)	missense	probably damaging	1.00
R8990:Bltp1	UTSW	3	36,921,221 (GRCm38)	missense	possibly damaging	0.60
R9021:Bltp1	UTSW	3	36,998,344 (GRCm38)	missense	probably benign	0.00
R9048:Bltp1	UTSW	3	37,011,777 (GRCm38)	missense
R9100:Bltp1	UTSW	3	37,044,758 (GRCm38)	missense
R9166:Bltp1	UTSW	3	36,987,367 (GRCm38)	missense	probably damaging	1.00
R9176:Bltp1	UTSW	3	36,956,703 (GRCm38)	missense	possibly damaging	0.82
R9202:Bltp1	UTSW	3	36,890,821 (GRCm38)	missense	probably benign
R9303:Bltp1	UTSW	3	37,044,820 (GRCm38)	missense
R9305:Bltp1	UTSW	3	37,044,820 (GRCm38)	missense
R9332:Bltp1	UTSW	3	37,050,840 (GRCm38)	missense
R9362:Bltp1	UTSW	3	36,957,013 (GRCm38)	missense	probably benign
R9493:Bltp1	UTSW	3	37,011,736 (GRCm38)	missense
R9534:Bltp1	UTSW	3	36,998,270 (GRCm38)	missense	probably benign	0.01
R9569:Bltp1	UTSW	3	37,012,621 (GRCm38)	missense
R9593:Bltp1	UTSW	3	36,947,941 (GRCm38)	missense	probably damaging	1.00
R9600:Bltp1	UTSW	3	37,041,416 (GRCm38)	nonsense	probably null
R9733:Bltp1	UTSW	3	37,048,583 (GRCm38)	missense
R9751:Bltp1	UTSW	3	37,011,740 (GRCm38)	missense
RF013:Bltp1	UTSW	3	37,050,757 (GRCm38)	critical splice acceptor site	probably benign
RF015:Bltp1	UTSW	3	37,050,748 (GRCm38)	critical splice acceptor site	probably benign
RF021:Bltp1	UTSW	3	37,050,748 (GRCm38)	critical splice acceptor site	probably benign
RF023:Bltp1	UTSW	3	37,050,760 (GRCm38)	critical splice acceptor site	probably benign
RF034:Bltp1	UTSW	3	37,050,760 (GRCm38)	critical splice acceptor site	probably benign
RF035:Bltp1	UTSW	3	37,050,758 (GRCm38)	critical splice acceptor site	probably benign
RF055:Bltp1	UTSW	3	37,050,757 (GRCm38)	critical splice acceptor site	probably benign
X0050:Bltp1	UTSW	3	36,957,128 (GRCm38)	missense	probably damaging	1.00
Z1088:Bltp1	UTSW	3	36,987,567 (GRCm38)	missense	probably damaging	1.00
Z1177:Bltp1	UTSW	3	36,983,440 (GRCm38)	missense	possibly damaging	0.88
Z1177:Bltp1	UTSW	3	36,919,950 (GRCm38)	missense	probably benign
Z1177:Bltp1	UTSW	3	37,036,707 (GRCm38)	missense

Predicted Primers

PCR Primer
(F):5'- TGGAGAAGGCATTACAGACCC -3'
(R):5'- GAGAACTGAAATGACTCAGCTTAAC -3'

Sequencing Primer
(F):5'- GGCATTACAGACCCTCGGACTC -3'
(R):5'- GACTCAGCTTAACAACTTAAAACTGG -3'

Posted On

2019-10-24