Incidental Mutation 'R7624:Wnk4'
| ID |
589338 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Wnk4
|
| Ensembl Gene |
ENSMUSG00000035112 |
| Gene Name |
WNK lysine deficient protein kinase 4 |
| Synonyms |
2010002J11Rik, Prkwnk4 |
| MMRRC Submission |
045689-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.238)
|
| Stock # |
R7624 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
101151393-101168235 bp(+) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
G to T
at 101155180 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Stop codon
at position 364
(E364*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000099397
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000042477]
[ENSMUST00000100414]
[ENSMUST00000103108]
[ENSMUST00000128260]
[ENSMUST00000139487]
[ENSMUST00000147741]
[ENSMUST00000170056]
|
| AlphaFold |
Q80UE6 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000042477
|
| SMART Domains |
Protein: ENSMUSP00000042088
Gene: ENSMUSG00000078656
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ESCRT-II
|
9 |
147 |
1.3e-64 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000100414
|
| SMART Domains |
Protein: ENSMUSP00000097981
Gene: ENSMUSG00000078656
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ESCRT-II
|
9 |
144 |
5e-61 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000103108
AA Change: E364*
|
| SMART Domains |
Protein: ENSMUSP00000099397
Gene: ENSMUSG00000035112
AA Change: E364*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
31 |
45 |
N/A |
INTRINSIC |
|
low complexity region
|
52 |
64 |
N/A |
INTRINSIC |
|
low complexity region
|
76 |
92 |
N/A |
INTRINSIC |
|
low complexity region
|
95 |
105 |
N/A |
INTRINSIC |
|
low complexity region
|
126 |
155 |
N/A |
INTRINSIC |
|
Pfam:Pkinase_Tyr
|
171 |
427 |
4.7e-42 |
PFAM |
|
Pfam:Pkinase
|
171 |
429 |
9e-55 |
PFAM |
|
Pfam:OSR1_C
|
450 |
486 |
3e-18 |
PFAM |
|
low complexity region
|
503 |
513 |
N/A |
INTRINSIC |
|
low complexity region
|
516 |
530 |
N/A |
INTRINSIC |
|
low complexity region
|
544 |
560 |
N/A |
INTRINSIC |
|
low complexity region
|
627 |
638 |
N/A |
INTRINSIC |
|
low complexity region
|
660 |
678 |
N/A |
INTRINSIC |
|
low complexity region
|
757 |
778 |
N/A |
INTRINSIC |
|
low complexity region
|
793 |
808 |
N/A |
INTRINSIC |
|
low complexity region
|
841 |
877 |
N/A |
INTRINSIC |
|
low complexity region
|
882 |
915 |
N/A |
INTRINSIC |
|
low complexity region
|
921 |
951 |
N/A |
INTRINSIC |
|
low complexity region
|
1014 |
1033 |
N/A |
INTRINSIC |
|
low complexity region
|
1093 |
1112 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000128260
|
| SMART Domains |
Protein: ENSMUSP00000127718
Gene: ENSMUSG00000001240
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
44 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000139487
|
| SMART Domains |
Protein: ENSMUSP00000129666
Gene: ENSMUSG00000035112
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
31 |
45 |
N/A |
INTRINSIC |
|
low complexity region
|
52 |
64 |
N/A |
INTRINSIC |
|
low complexity region
|
76 |
92 |
N/A |
INTRINSIC |
|
low complexity region
|
95 |
105 |
N/A |
INTRINSIC |
|
low complexity region
|
126 |
155 |
N/A |
INTRINSIC |
|
Pfam:Pkinase_Tyr
|
171 |
242 |
4e-8 |
PFAM |
|
Pfam:Pkinase
|
171 |
252 |
1.9e-10 |
PFAM |
|
low complexity region
|
269 |
283 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000147741
AA Change: E364*
|
| SMART Domains |
Protein: ENSMUSP00000131298
Gene: ENSMUSG00000035112
AA Change: E364*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
31 |
45 |
N/A |
INTRINSIC |
|
low complexity region
|
52 |
64 |
N/A |
INTRINSIC |
|
low complexity region
|
76 |
92 |
N/A |
INTRINSIC |
|
low complexity region
|
95 |
105 |
N/A |
INTRINSIC |
|
low complexity region
|
126 |
155 |
N/A |
INTRINSIC |
|
Pfam:Pkinase
|
171 |
394 |
9.3e-50 |
PFAM |
|
Pfam:Pkinase_Tyr
|
171 |
399 |
3.7e-38 |
PFAM |
|
low complexity region
|
401 |
413 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000170056
|
| SMART Domains |
Protein: ENSMUSP00000132123
Gene: ENSMUSG00000035112
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:OSR1_C
|
13 |
49 |
8.6e-20 |
PFAM |
|
low complexity region
|
66 |
76 |
N/A |
INTRINSIC |
|
low complexity region
|
79 |
93 |
N/A |
INTRINSIC |
|
low complexity region
|
107 |
123 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.9%
|
| Validation Efficiency |
99% (69/70) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB.[provided by RefSeq, Sep 2009]
PHENOTYPE: Mice homozygous for a null allele display increased Na+, K+ and Cl- urinary excretion, alkalosis and decreased plasma Cl-, K+, Mg2+ and renin levels. Mice homozygous for a point mutation exhibit acidosis, hypertension, increased circulating potassium levels and decreased potassium excretion. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 69 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Atm |
C |
A |
9: 53,366,068 (GRCm39) |
R2533L |
probably damaging |
Het |
| Caprin1 |
T |
A |
2: 103,603,022 (GRCm39) |
M514L |
possibly damaging |
Het |
| Ccdc78 |
A |
G |
17: 26,006,126 (GRCm39) |
E98G |
probably damaging |
Het |
| Cmya5 |
A |
T |
13: 93,226,865 (GRCm39) |
M2741K |
possibly damaging |
Het |
| Cnot1 |
T |
G |
8: 96,478,447 (GRCm39) |
R959S |
probably damaging |
Het |
| Col12a1 |
G |
T |
9: 79,553,076 (GRCm39) |
|
probably null |
Het |
| Col4a3 |
A |
G |
1: 82,696,605 (GRCm39) |
T177A |
probably benign |
Het |
| Cpa3 |
T |
C |
3: 20,279,307 (GRCm39) |
N211D |
possibly damaging |
Het |
| Cripto |
C |
T |
9: 110,775,017 (GRCm39) |
|
probably benign |
Het |
| Cryba1 |
T |
C |
11: 77,613,543 (GRCm39) |
Y36C |
probably damaging |
Het |
| Ctnna1 |
T |
A |
18: 35,377,897 (GRCm39) |
I632N |
probably benign |
Het |
| D630045J12Rik |
T |
C |
6: 38,126,498 (GRCm39) |
N1504S |
probably damaging |
Het |
| Dgkz |
C |
A |
2: 91,773,019 (GRCm39) |
R346L |
probably damaging |
Het |
| Dnajc21 |
G |
A |
15: 10,461,318 (GRCm39) |
R211C |
probably benign |
Het |
| Dnajc21 |
A |
T |
15: 10,461,320 (GRCm39) |
I210N |
probably damaging |
Het |
| Dscam |
T |
C |
16: 96,411,524 (GRCm39) |
D1784G |
probably damaging |
Het |
| Eya3 |
A |
G |
4: 132,400,262 (GRCm39) |
T94A |
probably benign |
Het |
| Fan1 |
T |
A |
7: 64,022,234 (GRCm39) |
N340Y |
probably damaging |
Het |
| Fat3 |
T |
C |
9: 15,871,165 (GRCm39) |
D3742G |
possibly damaging |
Het |
| Ficd |
T |
C |
5: 113,876,751 (GRCm39) |
F309L |
probably benign |
Het |
| Gfra1 |
A |
T |
19: 58,226,878 (GRCm39) |
M451K |
probably benign |
Het |
| Gm43517 |
T |
A |
12: 49,437,961 (GRCm39) |
L318Q |
|
Het |
| Gsc |
A |
T |
12: 104,439,310 (GRCm39) |
V22E |
possibly damaging |
Het |
| Il4ra |
T |
C |
7: 125,168,280 (GRCm39) |
Y100H |
probably damaging |
Het |
| Ilf3 |
T |
C |
9: 21,309,340 (GRCm39) |
S486P |
probably benign |
Het |
| Itga10 |
T |
A |
3: 96,560,269 (GRCm39) |
H594Q |
probably benign |
Het |
| Kcnf1 |
T |
C |
12: 17,226,137 (GRCm39) |
D28G |
probably benign |
Het |
| Kiss1 |
A |
G |
1: 133,257,160 (GRCm39) |
K53R |
possibly damaging |
Het |
| Lcn5 |
A |
G |
2: 25,551,426 (GRCm39) |
I182V |
probably benign |
Het |
| Lcorl |
T |
C |
5: 45,859,307 (GRCm39) |
D269G |
probably benign |
Het |
| Letm2 |
A |
T |
8: 26,082,553 (GRCm39) |
C174* |
probably null |
Het |
| Met |
T |
G |
6: 17,558,834 (GRCm39) |
V1154G |
probably damaging |
Het |
| Mindy3 |
A |
G |
2: 12,424,000 (GRCm39) |
S22P |
probably benign |
Het |
| Mroh2b |
G |
A |
15: 4,946,613 (GRCm39) |
R471Q |
probably damaging |
Het |
| Nfe2l3 |
T |
C |
6: 51,435,252 (GRCm39) |
L604P |
probably damaging |
Het |
| Or12e10 |
A |
G |
2: 87,640,683 (GRCm39) |
Q173R |
probably damaging |
Het |
| Or14a256 |
A |
G |
7: 86,265,769 (GRCm39) |
F28S |
possibly damaging |
Het |
| Or5h18 |
T |
A |
16: 58,847,382 (GRCm39) |
Q296L |
possibly damaging |
Het |
| Or8b3b |
C |
T |
9: 38,583,919 (GRCm39) |
V274I |
probably benign |
Het |
| Or8u9 |
A |
T |
2: 86,001,564 (GRCm39) |
I199N |
possibly damaging |
Het |
| Or9r7 |
A |
C |
10: 129,962,455 (GRCm39) |
I157S |
probably damaging |
Het |
| Pcdha9 |
T |
A |
18: 37,132,849 (GRCm39) |
Y639* |
probably null |
Het |
| Pom121l2 |
A |
T |
13: 22,167,699 (GRCm39) |
I657L |
probably damaging |
Het |
| Prr14l |
T |
A |
5: 32,986,967 (GRCm39) |
T843S |
possibly damaging |
Het |
| Rln1 |
A |
T |
19: 29,309,499 (GRCm39) |
N93K |
probably damaging |
Het |
| Rpl3l |
A |
T |
17: 24,951,401 (GRCm39) |
M101L |
probably benign |
Het |
| Rtkn |
A |
G |
6: 83,129,158 (GRCm39) |
Y551C |
probably benign |
Het |
| Rundc1 |
G |
C |
11: 101,324,305 (GRCm39) |
R337P |
possibly damaging |
Het |
| Scarf1 |
T |
A |
11: 75,405,242 (GRCm39) |
|
probably null |
Het |
| Serpinb1b |
T |
A |
13: 33,275,622 (GRCm39) |
|
probably null |
Het |
| Sgsm1 |
A |
T |
5: 113,422,201 (GRCm39) |
C484* |
probably null |
Het |
| Slc22a19 |
T |
A |
19: 7,650,668 (GRCm39) |
K547* |
probably null |
Het |
| Slc22a19 |
T |
C |
19: 7,671,183 (GRCm39) |
T177A |
probably benign |
Het |
| Slc6a5 |
A |
C |
7: 49,591,614 (GRCm39) |
K526N |
probably benign |
Het |
| Sqle |
G |
A |
15: 59,202,603 (GRCm39) |
R519Q |
probably benign |
Het |
| Stard9 |
T |
C |
2: 120,518,627 (GRCm39) |
I517T |
probably benign |
Het |
| Taf15 |
A |
T |
11: 83,395,849 (GRCm39) |
D518V |
unknown |
Het |
| Tenm4 |
A |
G |
7: 96,545,192 (GRCm39) |
M2440V |
possibly damaging |
Het |
| Tm6sf1 |
A |
G |
7: 81,518,458 (GRCm39) |
M122V |
possibly damaging |
Het |
| Tmprss9 |
T |
A |
10: 80,728,053 (GRCm39) |
S548T |
possibly damaging |
Het |
| Trim62 |
A |
T |
4: 128,777,471 (GRCm39) |
|
probably benign |
Het |
| Ugt2b34 |
C |
T |
5: 87,039,141 (GRCm39) |
V507M |
possibly damaging |
Het |
| Usp16 |
T |
A |
16: 87,273,693 (GRCm39) |
M423K |
probably benign |
Het |
| Vmn1r199 |
T |
A |
13: 22,566,906 (GRCm39) |
S67T |
probably benign |
Het |
| Vmn1r62 |
A |
T |
7: 5,678,600 (GRCm39) |
M94L |
probably benign |
Het |
| Xpo1 |
T |
A |
11: 23,232,584 (GRCm39) |
I368N |
probably damaging |
Het |
| Zfp366 |
A |
G |
13: 99,382,804 (GRCm39) |
T656A |
probably benign |
Het |
| Zfp934 |
T |
C |
13: 62,666,338 (GRCm39) |
M113V |
probably benign |
Het |
| Zkscan2 |
A |
G |
7: 123,097,994 (GRCm39) |
V134A |
probably damaging |
Het |
|
| Other mutations in Wnk4 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00231:Wnk4
|
APN |
11 |
101,159,574 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
IGL00535:Wnk4
|
APN |
11 |
101,155,175 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01401:Wnk4
|
APN |
11 |
101,167,509 (GRCm39) |
splice site |
probably benign |
|
|
IGL01931:Wnk4
|
APN |
11 |
101,159,310 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01977:Wnk4
|
APN |
11 |
101,156,240 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02165:Wnk4
|
APN |
11 |
101,166,117 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02197:Wnk4
|
APN |
11 |
101,154,783 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02457:Wnk4
|
APN |
11 |
101,160,389 (GRCm39) |
splice site |
probably benign |
|
|
IGL02963:Wnk4
|
APN |
11 |
101,167,039 (GRCm39) |
unclassified |
probably benign |
|
|
ashamed
|
UTSW |
11 |
101,156,257 (GRCm39) |
missense |
probably damaging |
1.00 |
|
blushing
|
UTSW |
11 |
101,156,203 (GRCm39) |
missense |
probably damaging |
0.96 |
|
Caught_dead
|
UTSW |
11 |
101,155,156 (GRCm39) |
missense |
probably damaging |
1.00 |
|
lowered
|
UTSW |
11 |
101,159,318 (GRCm39) |
critical splice donor site |
probably null |
|
|
mortification
|
UTSW |
11 |
101,154,720 (GRCm39) |
makesense |
probably null |
|
|
shame
|
UTSW |
11 |
101,153,682 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0066:Wnk4
|
UTSW |
11 |
101,156,261 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0317:Wnk4
|
UTSW |
11 |
101,159,630 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0628:Wnk4
|
UTSW |
11 |
101,165,849 (GRCm39) |
missense |
probably benign |
0.10 |
|
R0630:Wnk4
|
UTSW |
11 |
101,156,212 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0710:Wnk4
|
UTSW |
11 |
101,164,932 (GRCm39) |
missense |
probably benign |
0.22 |
|
R1290:Wnk4
|
UTSW |
11 |
101,167,166 (GRCm39) |
unclassified |
probably benign |
|
|
R1482:Wnk4
|
UTSW |
11 |
101,160,462 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1775:Wnk4
|
UTSW |
11 |
101,167,166 (GRCm39) |
unclassified |
probably benign |
|
|
R2005:Wnk4
|
UTSW |
11 |
101,154,716 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2229:Wnk4
|
UTSW |
11 |
101,166,467 (GRCm39) |
unclassified |
probably benign |
|
|
R2258:Wnk4
|
UTSW |
11 |
101,165,861 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2323:Wnk4
|
UTSW |
11 |
101,159,307 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3081:Wnk4
|
UTSW |
11 |
101,167,717 (GRCm39) |
splice site |
probably benign |
|
|
R3763:Wnk4
|
UTSW |
11 |
101,160,114 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4196:Wnk4
|
UTSW |
11 |
101,160,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4447:Wnk4
|
UTSW |
11 |
101,159,277 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R4614:Wnk4
|
UTSW |
11 |
101,164,937 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4751:Wnk4
|
UTSW |
11 |
101,167,188 (GRCm39) |
unclassified |
probably benign |
|
|
R4948:Wnk4
|
UTSW |
11 |
101,159,107 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5067:Wnk4
|
UTSW |
11 |
101,153,682 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5073:Wnk4
|
UTSW |
11 |
101,152,014 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5107:Wnk4
|
UTSW |
11 |
101,166,364 (GRCm39) |
unclassified |
probably benign |
|
|
R5181:Wnk4
|
UTSW |
11 |
101,156,203 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5205:Wnk4
|
UTSW |
11 |
101,155,964 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5252:Wnk4
|
UTSW |
11 |
101,159,574 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R5273:Wnk4
|
UTSW |
11 |
101,154,695 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5293:Wnk4
|
UTSW |
11 |
101,166,023 (GRCm39) |
unclassified |
probably benign |
|
|
R5609:Wnk4
|
UTSW |
11 |
101,166,462 (GRCm39) |
unclassified |
probably benign |
|
|
R5915:Wnk4
|
UTSW |
11 |
101,154,720 (GRCm39) |
makesense |
probably null |
|
|
R5931:Wnk4
|
UTSW |
11 |
101,152,047 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6126:Wnk4
|
UTSW |
11 |
101,167,174 (GRCm39) |
unclassified |
probably benign |
|
|
R6164:Wnk4
|
UTSW |
11 |
101,165,894 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R6191:Wnk4
|
UTSW |
11 |
101,155,156 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6267:Wnk4
|
UTSW |
11 |
101,164,824 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6274:Wnk4
|
UTSW |
11 |
101,156,257 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6296:Wnk4
|
UTSW |
11 |
101,164,824 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7132:Wnk4
|
UTSW |
11 |
101,152,026 (GRCm39) |
missense |
probably benign |
0.22 |
|
R7251:Wnk4
|
UTSW |
11 |
101,155,979 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R7352:Wnk4
|
UTSW |
11 |
101,155,244 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7404:Wnk4
|
UTSW |
11 |
101,159,318 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7634:Wnk4
|
UTSW |
11 |
101,153,721 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7780:Wnk4
|
UTSW |
11 |
101,160,403 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8006:Wnk4
|
UTSW |
11 |
101,159,182 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8046:Wnk4
|
UTSW |
11 |
101,164,918 (GRCm39) |
missense |
probably benign |
0.20 |
|
R8143:Wnk4
|
UTSW |
11 |
101,153,625 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8458:Wnk4
|
UTSW |
11 |
101,166,147 (GRCm39) |
nonsense |
probably null |
|
|
R8735:Wnk4
|
UTSW |
11 |
101,167,092 (GRCm39) |
missense |
unknown |
|
|
R9025:Wnk4
|
UTSW |
11 |
101,153,641 (GRCm39) |
nonsense |
probably null |
|
|
R9206:Wnk4
|
UTSW |
11 |
101,164,882 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9295:Wnk4
|
UTSW |
11 |
101,160,078 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9610:Wnk4
|
UTSW |
11 |
101,159,250 (GRCm39) |
nonsense |
probably null |
|
|
R9611:Wnk4
|
UTSW |
11 |
101,159,250 (GRCm39) |
nonsense |
probably null |
|
|
R9674:Wnk4
|
UTSW |
11 |
101,166,874 (GRCm39) |
missense |
unknown |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GCTATTAAGACTCCCTCCGACC -3'
(R):5'- CACCAGGGCATCTTTCTGTCTG -3'
Sequencing Primer
(F):5'- CCCCATATGATATACCCAAGTGGAGG -3'
(R):5'- GGCATCTTTCTGTCTGGCCTG -3'
|
| Posted On |
2019-10-24 |
Incidental Mutation