Mutagenetix > Incidental Mutation

Incidental Mutation 'R7368:Myo15a'

590987

Institutional Source

Beutler Lab

Gene Symbol

Myo15a

Ensembl Gene

ENSMUSG00000042678

Gene Name

myosin XVA

Synonyms

Myo15

MMRRC Submission

045452-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R7368 (G1)

Quality Score

183.009

Status

Validated

Chromosome

Chromosomal Location

60469339-60528369 bp(+) (GRCm38)

Type of Mutation

splice site

DNA Base Change (assembly)

G to T at 60490915 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s): [ENSMUST00000071880] [ENSMUST00000081823] [ENSMUST00000094135]

AlphaFold

no structure available at present

Predicted Effect

probably null
Transcript: ENSMUST00000071880

SMART Domains

Protein: ENSMUSP00000071777
Gene: ENSMUSG00000042678

Domain	Start	End	E-Value	Type
low complexity region	4	24	N/A	INTRINSIC
low complexity region	87	100	N/A	INTRINSIC
low complexity region	107	120	N/A	INTRINSIC
low complexity region	269	292	N/A	INTRINSIC
low complexity region	295	306	N/A	INTRINSIC
low complexity region	311	325	N/A	INTRINSIC
low complexity region	349	384	N/A	INTRINSIC
low complexity region	425	435	N/A	INTRINSIC
low complexity region	487	498	N/A	INTRINSIC
low complexity region	502	509	N/A	INTRINSIC
low complexity region	653	681	N/A	INTRINSIC
low complexity region	692	705	N/A	INTRINSIC
low complexity region	737	747	N/A	INTRINSIC
low complexity region	758	775	N/A	INTRINSIC
low complexity region	781	792	N/A	INTRINSIC
low complexity region	796	809	N/A	INTRINSIC
low complexity region	825	849	N/A	INTRINSIC
low complexity region	883	897	N/A	INTRINSIC
low complexity region	1067	1082	N/A	INTRINSIC
low complexity region	1115	1130	N/A	INTRINSIC
MYSc	1200	1884	N/A	SMART
IQ	1885	1907	1.63e-1	SMART
IQ	1908	1930	1.77e-2	SMART
IQ	1931	1953	2.97e2	SMART
low complexity region	1955	1974	N/A	INTRINSIC
low complexity region	1992	2006	N/A	INTRINSIC
MyTH4	2049	2195	1.8e-42	SMART
low complexity region	2396	2405	N/A	INTRINSIC
low complexity region	2451	2461	N/A	INTRINSIC
Blast:MYSc	2665	2848	2e-14	BLAST
SH3	2851	2933	1.55e-4	SMART
low complexity region	2949	2962	N/A	INTRINSIC
MyTH4	3031	3185	5.59e-48	SMART
B41	3188	3400	6.94e-3	SMART

Predicted Effect

probably null
Transcript: ENSMUST00000081823

SMART Domains

Protein: ENSMUSP00000080507
Gene: ENSMUSG00000042678

Domain	Start	End	E-Value	Type
MYSc	13	697	N/A	SMART
IQ	698	720	1.63e-1	SMART
IQ	721	743	1.77e-2	SMART
IQ	744	766	2.97e2	SMART
low complexity region	787	801	N/A	INTRINSIC
MyTH4	844	990	1.8e-42	SMART
low complexity region	1191	1200	N/A	INTRINSIC
low complexity region	1246	1256	N/A	INTRINSIC
Blast:MYSc	1460	1643	7e-15	BLAST
SH3	1646	1728	1.55e-4	SMART
low complexity region	1744	1757	N/A	INTRINSIC
MyTH4	1826	1980	5.59e-48	SMART
B41	1983	2195	6.94e-3	SMART

Predicted Effect

probably null
Transcript: ENSMUST00000094135

SMART Domains

Protein: ENSMUSP00000091686
Gene: ENSMUSG00000042678

Domain	Start	End	E-Value	Type
low complexity region	4	24	N/A	INTRINSIC
low complexity region	87	100	N/A	INTRINSIC
low complexity region	107	120	N/A	INTRINSIC
low complexity region	269	292	N/A	INTRINSIC
low complexity region	295	306	N/A	INTRINSIC
low complexity region	311	325	N/A	INTRINSIC
low complexity region	349	384	N/A	INTRINSIC
low complexity region	425	435	N/A	INTRINSIC
low complexity region	487	498	N/A	INTRINSIC
low complexity region	502	509	N/A	INTRINSIC
low complexity region	653	681	N/A	INTRINSIC
low complexity region	692	705	N/A	INTRINSIC
low complexity region	737	747	N/A	INTRINSIC
low complexity region	758	775	N/A	INTRINSIC
low complexity region	781	792	N/A	INTRINSIC
low complexity region	796	809	N/A	INTRINSIC
low complexity region	825	849	N/A	INTRINSIC
low complexity region	883	897	N/A	INTRINSIC
low complexity region	1067	1082	N/A	INTRINSIC
low complexity region	1115	1130	N/A	INTRINSIC
MYSc	1200	1884	N/A	SMART
IQ	1885	1907	1.63e-1	SMART
IQ	1908	1930	1.77e-2	SMART
IQ	1931	1953	2.97e2	SMART
low complexity region	1974	1988	N/A	INTRINSIC
MyTH4	2031	2177	1.8e-42	SMART
low complexity region	2378	2387	N/A	INTRINSIC
low complexity region	2433	2443	N/A	INTRINSIC
Blast:MYSc	2647	2830	2e-14	BLAST
SH3	2833	2915	1.55e-4	SMART
low complexity region	2931	2944	N/A	INTRINSIC
MyTH4	3013	3167	5.59e-48	SMART
B41	3170	3382	6.94e-3	SMART

Predicted Effect

probably null
Transcript: ENSMUST00000126522

SMART Domains

Protein: ENSMUSP00000120839
Gene: ENSMUSG00000042678

Domain	Start	End	E-Value	Type
MYSc	34	716	N/A	SMART
IQ	717	739	1.63e-1	SMART
IQ	740	762	1.77e-2	SMART
IQ	763	785	2.97e2	SMART
low complexity region	806	820	N/A	INTRINSIC
MyTH4	863	1009	1.8e-42	SMART
low complexity region	1210	1219	N/A	INTRINSIC
low complexity region	1265	1275	N/A	INTRINSIC
Blast:MYSc	1479	1662	5e-15	BLAST
SH3	1665	1747	1.55e-4	SMART
low complexity region	1763	1776	N/A	INTRINSIC

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.7%
20x: 99.1%

Validation Efficiency

98% (61/62)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes an unconventional myosin. This protein differs from other myosins in that it has a long N-terminal extension preceding the conserved motor domain. Studies in mice suggest that this protein is necessary for actin organization in the hair cells of the cochlea. Mutations in this gene have been associated with profound, congenital, neurosensory, nonsyndromal deafness. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Read-through transcripts containing an upstream gene and this gene have been identified, but they are not thought to encode a fusion protein. Several alternatively spliced transcript variants have been described, but their full length sequences have not been determined. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mutations in this gene result in profound deafness and neurological behavior. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 61 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcd4	A	T	12: 84,612,865 (GRCm38)	F153I	possibly damaging	Het
Adcy1	G	A	11: 7,144,765 (GRCm38)	V564I	probably damaging	Het
Apol9b	T	C	15: 77,735,934 (GRCm38)	I310T	possibly damaging	Het
Arhgef28	C	A	13: 97,996,862 (GRCm38)	V366F	probably benign	Het
B020004C17Rik	C	T	14: 57,017,316 (GRCm38)	T199I	possibly damaging	Het
Carmil2	C	T	8: 105,690,835 (GRCm38)	T575I	possibly damaging	Het
Catsper1	A	T	19: 5,336,663 (GRCm38)	Q308L	unknown	Het
Cpa2	T	A	6: 30,551,990 (GRCm38)	S239T	probably damaging	Het
Cyrib	A	T	15: 63,938,658 (GRCm38)		probably null	Het
Ddit3	G	A	10: 127,295,907 (GRCm38)	G108D	probably damaging	Het
Dnah3	T	C	7: 120,029,016 (GRCm38)	I1473V	probably benign	Het
Dscam	A	G	16: 96,643,931 (GRCm38)	V1520A	probably benign	Het
Edc4	TAGTAGCAGCAGCAGTAGCAGCAGCAG	TAGTAGCAGCAGCAG	8: 105,888,405 (GRCm38)		probably benign	Het
Ednrb	T	A	14: 103,820,017 (GRCm38)	I370F	probably benign	Het
Ehd3	A	G	17: 73,827,462 (GRCm38)	E272G	possibly damaging	Het
Epha7	C	T	4: 28,871,937 (GRCm38)	S422L	probably benign	Het
Fkbp11	T	C	15: 98,724,426 (GRCm38)	K189E	unknown	Het
Frem1	T	A	4: 82,966,144 (GRCm38)	E1190D	probably benign	Het
Gabrg2	A	C	11: 41,976,563 (GRCm38)	Y76*	probably null	Het
Gm11437	T	A	11: 84,167,472 (GRCm38)		probably benign	Het
Gm8947	C	A	1: 151,193,096 (GRCm38)	Q227K	probably benign	Het
Gm9195	A	G	14: 72,480,056 (GRCm38)	F279S	probably damaging	Het
Gpbp1l1	T	C	4: 116,573,458 (GRCm38)	I42T	probably benign	Het
Hdac5	A	T	11: 102,197,381 (GRCm38)	V939E	probably null	Het
Hivep3	CGG	CG	4: 120,097,911 (GRCm38)	1141	probably null	Het
Kitl	A	T	10: 100,016,081 (GRCm38)	I21F	probably benign	Het
Krt1	T	C	15: 101,846,872 (GRCm38)	D484G	probably damaging	Het
Larp1	C	A	11: 58,048,078 (GRCm38)	P527T	probably damaging	Het
Lrp5	A	G	19: 3,620,085 (GRCm38)	V673A	possibly damaging	Het
Lrp6	G	T	6: 134,450,818 (GRCm38)	P1604T	probably damaging	Het
Mmp27	G	A	9: 7,577,317 (GRCm38)	V228M	probably damaging	Het
Ms4a6d	G	A	19: 11,590,073 (GRCm38)	Q155*	probably null	Het
Myt1	A	G	2: 181,782,591 (GRCm38)	K26E	possibly damaging	Het
Nek1	T	A	8: 61,089,707 (GRCm38)	I777N	probably benign	Het
Nlrc5	C	T	8: 94,476,393 (GRCm38)	R374*	probably null	Het
Nol8	T	C	13: 49,661,219 (GRCm38)	S268P	probably benign	Het
Nynrin	T	A	14: 55,870,511 (GRCm38)	L1025Q	probably damaging	Het
Or8h9	A	G	2: 86,959,258 (GRCm38)	S67P	probably damaging	Het
Osbpl3	A	T	6: 50,348,098 (GRCm38)	L140H	probably damaging	Het
Pcnt	T	C	10: 76,400,001 (GRCm38)	N1382S	probably benign	Het
Pef1	T	A	4: 130,127,385 (GRCm38)	L244*	probably null	Het
Phf11a	T	C	14: 59,280,725 (GRCm38)	E191G	probably benign	Het
Polr3a	A	T	14: 24,467,076 (GRCm38)	D702E	probably damaging	Het
Ptch1	C	T	13: 63,511,984 (GRCm38)	G1285D	probably benign	Het
Ptpn3	T	C	4: 57,221,993 (GRCm38)	D566G	probably damaging	Het
Pwp2	C	T	10: 78,182,480 (GRCm38)	G126R	probably damaging	Het
Scgb1b12	T	C	7: 32,334,567 (GRCm38)	I84T	probably damaging	Het
Sh2b1	A	T	7: 126,468,513 (GRCm38)	D618E	possibly damaging	Het
Slc35f5	T	A	1: 125,584,519 (GRCm38)	V352E	probably damaging	Het
Sppl2c	A	G	11: 104,187,604 (GRCm38)	E410G	probably damaging	Het
St6galnac2	T	C	11: 116,679,979 (GRCm38)	Y261C	probably damaging	Het
Stra6	G	A	9: 58,151,260 (GRCm38)	R468Q	probably benign	Het
Taf3	T	C	2: 9,916,377 (GRCm38)	H924R	unknown	Het
Tbx18	C	A	9: 87,730,697 (GRCm38)	V50L	probably benign	Het
Tgoln1	G	C	6: 72,616,278 (GRCm38)	T73R	probably benign	Het
Unc45b	C	T	11: 82,942,495 (GRCm38)	T845I	probably benign	Het
Usp15	T	C	10: 123,196,893 (GRCm38)	D8G	possibly damaging	Het
Vmn2r91	A	G	17: 18,136,278 (GRCm38)	I736V	possibly damaging	Het
Vps13c	C	A	9: 67,914,073 (GRCm38)	D1288E	probably benign	Het
Zfp458	T	A	13: 67,257,236 (GRCm38)	M380L	probably benign	Het
Zfp638	A	G	6: 83,929,455 (GRCm38)	N201D	possibly damaging	Het

Other mutations in Myo15a

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00845:Myo15a	APN	11	60,477,779 (GRCm38)	missense	probably damaging	1.00
IGL01011:Myo15a	APN	11	60,476,992 (GRCm38)	missense	probably benign	0.33
IGL01100:Myo15a	APN	11	60,511,158 (GRCm38)	missense	probably damaging	1.00
IGL01357:Myo15a	APN	11	60,502,289 (GRCm38)	splice site	probably benign
IGL01634:Myo15a	APN	11	60,495,472 (GRCm38)	missense	probably damaging	1.00
IGL01763:Myo15a	APN	11	60,521,738 (GRCm38)	missense	probably benign	0.07
IGL01901:Myo15a	APN	11	60,527,434 (GRCm38)	utr 3 prime	probably benign
IGL01931:Myo15a	APN	11	60,496,138 (GRCm38)	missense	probably damaging	1.00
IGL02006:Myo15a	APN	11	60,511,128 (GRCm38)	missense	probably damaging	1.00
IGL02041:Myo15a	APN	11	60,506,863 (GRCm38)	missense	probably damaging	0.99
IGL02094:Myo15a	APN	11	60,510,647 (GRCm38)	unclassified	probably benign
IGL02122:Myo15a	APN	11	60,483,466 (GRCm38)	missense	probably benign	0.23
IGL02153:Myo15a	APN	11	60,498,397 (GRCm38)	missense	probably damaging	1.00
IGL02328:Myo15a	APN	11	60,526,607 (GRCm38)	missense	probably benign	0.13
IGL02330:Myo15a	APN	11	60,477,161 (GRCm38)	missense	possibly damaging	0.94
IGL02431:Myo15a	APN	11	60,510,639 (GRCm38)	missense	possibly damaging	0.73
IGL02639:Myo15a	APN	11	60,478,621 (GRCm38)	missense	probably benign
IGL02659:Myo15a	APN	11	60,491,783 (GRCm38)	splice site	probably benign
IGL02800:Myo15a	APN	11	60,502,369 (GRCm38)	missense	probably damaging	1.00
IGL02812:Myo15a	APN	11	60,477,179 (GRCm38)	missense	probably benign	0.15
IGL02863:Myo15a	APN	11	60,478,127 (GRCm38)	missense	probably damaging	1.00
IGL02873:Myo15a	APN	11	60,483,482 (GRCm38)	missense	probably damaging	1.00
IGL02990:Myo15a	APN	11	60,479,440 (GRCm38)	missense	probably benign	0.02
IGL03011:Myo15a	APN	11	60,509,531 (GRCm38)	splice site	probably benign
IGL03243:Myo15a	APN	11	60,496,518 (GRCm38)	missense	probably damaging	1.00
IGL03297:Myo15a	APN	11	60,479,141 (GRCm38)	missense	probably damaging	1.00
novichok	UTSW	11	60,481,740 (GRCm38)	critical splice donor site	probably null
parker	UTSW	11	60,520,914 (GRCm38)	critical splice donor site	probably null
Typhoon	UTSW	11	60,487,425 (GRCm38)	critical splice donor site	probably null
PIT4131001:Myo15a	UTSW	11	60,495,454 (GRCm38)	missense	probably damaging	1.00
PIT4131001:Myo15a	UTSW	11	60,483,127 (GRCm38)	missense	probably damaging	1.00
R0133:Myo15a	UTSW	11	60,477,850 (GRCm38)	missense	possibly damaging	0.94
R0265:Myo15a	UTSW	11	60,514,897 (GRCm38)	critical splice acceptor site	probably null
R0389:Myo15a	UTSW	11	60,478,538 (GRCm38)	missense	probably benign
R0416:Myo15a	UTSW	11	60,511,174 (GRCm38)	missense	probably damaging	1.00
R0449:Myo15a	UTSW	11	60,509,596 (GRCm38)	missense	possibly damaging	0.92
R0477:Myo15a	UTSW	11	60,520,914 (GRCm38)	critical splice donor site	probably null
R0543:Myo15a	UTSW	11	60,479,051 (GRCm38)	missense	probably benign
R0546:Myo15a	UTSW	11	60,506,313 (GRCm38)	missense	probably damaging	1.00
R0555:Myo15a	UTSW	11	60,521,638 (GRCm38)	missense	probably damaging	1.00
R0639:Myo15a	UTSW	11	60,479,336 (GRCm38)	missense	probably benign	0.12
R0723:Myo15a	UTSW	11	60,478,977 (GRCm38)	missense	possibly damaging	0.94
R0837:Myo15a	UTSW	11	60,487,251 (GRCm38)	missense	probably damaging	0.98
R0865:Myo15a	UTSW	11	60,491,688 (GRCm38)	missense	probably damaging	1.00
R0899:Myo15a	UTSW	11	60,477,185 (GRCm38)	missense	possibly damaging	0.87
R1022:Myo15a	UTSW	11	60,479,616 (GRCm38)	missense	probably benign	0.00
R1024:Myo15a	UTSW	11	60,479,616 (GRCm38)	missense	probably benign	0.00
R1035:Myo15a	UTSW	11	60,510,558 (GRCm38)	unclassified	probably benign
R1109:Myo15a	UTSW	11	60,493,066 (GRCm38)	missense	probably damaging	1.00
R1170:Myo15a	UTSW	11	60,479,407 (GRCm38)	missense	probably benign	0.04
R1241:Myo15a	UTSW	11	60,499,430 (GRCm38)	missense	possibly damaging	0.58
R1392:Myo15a	UTSW	11	60,477,974 (GRCm38)	missense	possibly damaging	0.95
R1392:Myo15a	UTSW	11	60,477,974 (GRCm38)	missense	possibly damaging	0.95
R1434:Myo15a	UTSW	11	60,504,331 (GRCm38)	missense	probably benign	0.00
R1450:Myo15a	UTSW	11	60,495,482 (GRCm38)	missense	probably damaging	1.00
R1456:Myo15a	UTSW	11	60,508,202 (GRCm38)	missense	probably damaging	1.00
R1468:Myo15a	UTSW	11	60,506,006 (GRCm38)	missense	probably damaging	1.00
R1468:Myo15a	UTSW	11	60,506,006 (GRCm38)	missense	probably damaging	1.00
R1548:Myo15a	UTSW	11	60,488,238 (GRCm38)	missense	probably damaging	1.00
R1551:Myo15a	UTSW	11	60,492,965 (GRCm38)	missense	possibly damaging	0.70
R1571:Myo15a	UTSW	11	60,518,464 (GRCm38)	missense	probably damaging	1.00
R1662:Myo15a	UTSW	11	60,501,701 (GRCm38)	missense	probably damaging	1.00
R1777:Myo15a	UTSW	11	60,514,936 (GRCm38)	missense	probably benign
R1778:Myo15a	UTSW	11	60,478,412 (GRCm38)	missense	possibly damaging	0.57
R1847:Myo15a	UTSW	11	60,499,495 (GRCm38)	nonsense	probably null
R1875:Myo15a	UTSW	11	60,507,528 (GRCm38)	missense	probably damaging	0.99
R1944:Myo15a	UTSW	11	60,502,083 (GRCm38)	missense	probably damaging	0.99
R1945:Myo15a	UTSW	11	60,502,083 (GRCm38)	missense	probably damaging	0.99
R2013:Myo15a	UTSW	11	60,494,231 (GRCm38)	missense	probably damaging	1.00
R2107:Myo15a	UTSW	11	60,491,810 (GRCm38)	missense	probably damaging	1.00
R2108:Myo15a	UTSW	11	60,491,810 (GRCm38)	missense	probably damaging	1.00
R2112:Myo15a	UTSW	11	60,494,168 (GRCm38)	missense	probably damaging	0.99
R2147:Myo15a	UTSW	11	60,510,229 (GRCm38)	missense	possibly damaging	0.66
R2196:Myo15a	UTSW	11	60,510,021 (GRCm38)	nonsense	probably null
R2207:Myo15a	UTSW	11	60,506,034 (GRCm38)	missense	probably benign	0.01
R2245:Myo15a	UTSW	11	60,509,099 (GRCm38)	missense	probably damaging	1.00
R2367:Myo15a	UTSW	11	60,517,238 (GRCm38)	missense	probably damaging	0.99
R2374:Myo15a	UTSW	11	60,478,843 (GRCm38)	missense	possibly damaging	0.88
R2438:Myo15a	UTSW	11	60,483,052 (GRCm38)	missense	probably damaging	1.00
R3154:Myo15a	UTSW	11	60,479,360 (GRCm38)	splice site	probably null
R3423:Myo15a	UTSW	11	60,510,300 (GRCm38)	critical splice donor site	probably null
R3551:Myo15a	UTSW	11	60,509,663 (GRCm38)	missense	possibly damaging	0.93
R3552:Myo15a	UTSW	11	60,509,663 (GRCm38)	missense	possibly damaging	0.93
R3612:Myo15a	UTSW	11	60,477,679 (GRCm38)	missense	probably damaging	1.00
R3620:Myo15a	UTSW	11	60,478,642 (GRCm38)	missense	possibly damaging	0.63
R3713:Myo15a	UTSW	11	60,479,231 (GRCm38)	missense	possibly damaging	0.55
R3714:Myo15a	UTSW	11	60,479,231 (GRCm38)	missense	possibly damaging	0.55
R3715:Myo15a	UTSW	11	60,479,231 (GRCm38)	missense	possibly damaging	0.55
R3783:Myo15a	UTSW	11	60,477,572 (GRCm38)	missense	probably damaging	0.97
R3784:Myo15a	UTSW	11	60,477,572 (GRCm38)	missense	probably damaging	0.97
R3785:Myo15a	UTSW	11	60,477,572 (GRCm38)	missense	probably damaging	0.97
R3786:Myo15a	UTSW	11	60,477,572 (GRCm38)	missense	probably damaging	0.97
R3787:Myo15a	UTSW	11	60,477,572 (GRCm38)	missense	probably damaging	0.97
R3894:Myo15a	UTSW	11	60,504,319 (GRCm38)	missense	probably benign	0.00
R3962:Myo15a	UTSW	11	60,479,828 (GRCm38)	missense	probably benign	0.00
R4082:Myo15a	UTSW	11	60,487,196 (GRCm38)	missense	possibly damaging	0.92
R4555:Myo15a	UTSW	11	60,496,937 (GRCm38)	missense	probably damaging	1.00
R4641:Myo15a	UTSW	11	60,503,041 (GRCm38)	missense	probably damaging	1.00
R4665:Myo15a	UTSW	11	60,504,879 (GRCm38)	critical splice acceptor site	probably null
R4713:Myo15a	UTSW	11	60,479,930 (GRCm38)	missense	probably benign	0.21
R4820:Myo15a	UTSW	11	60,476,915 (GRCm38)	missense	probably damaging	0.98
R5013:Myo15a	UTSW	11	60,491,667 (GRCm38)	missense	probably damaging	1.00
R5051:Myo15a	UTSW	11	60,487,425 (GRCm38)	critical splice donor site	probably null
R5187:Myo15a	UTSW	11	60,503,614 (GRCm38)	missense	probably damaging	1.00
R5230:Myo15a	UTSW	11	60,502,848 (GRCm38)	missense	possibly damaging	0.68
R5277:Myo15a	UTSW	11	60,477,114 (GRCm38)	nonsense	probably null
R5345:Myo15a	UTSW	11	60,497,538 (GRCm38)	missense	probably damaging	0.99
R5349:Myo15a	UTSW	11	60,493,583 (GRCm38)	missense	probably damaging	1.00
R5356:Myo15a	UTSW	11	60,498,366 (GRCm38)	missense	probably damaging	1.00
R5445:Myo15a	UTSW	11	60,520,777 (GRCm38)	nonsense	probably null
R5477:Myo15a	UTSW	11	60,477,677 (GRCm38)	missense	probably damaging	1.00
R5629:Myo15a	UTSW	11	60,479,752 (GRCm38)	missense	probably benign
R5728:Myo15a	UTSW	11	60,488,896 (GRCm38)	missense	probably damaging	1.00
R5818:Myo15a	UTSW	11	60,497,951 (GRCm38)	missense	probably benign	0.06
R5952:Myo15a	UTSW	11	60,479,420 (GRCm38)	missense	possibly damaging	0.50
R6338:Myo15a	UTSW	11	60,478,133 (GRCm38)	missense	probably damaging	0.99
R6467:Myo15a	UTSW	11	60,526,661 (GRCm38)	critical splice donor site	probably null
R6488:Myo15a	UTSW	11	60,478,487 (GRCm38)	missense	possibly damaging	0.86
R6521:Myo15a	UTSW	11	60,502,369 (GRCm38)	missense	probably damaging	1.00
R6645:Myo15a	UTSW	11	60,477,292 (GRCm38)	missense	probably benign	0.00
R6702:Myo15a	UTSW	11	60,492,992 (GRCm38)	missense	probably benign	0.16
R6703:Myo15a	UTSW	11	60,492,992 (GRCm38)	missense	probably benign	0.16
R6821:Myo15a	UTSW	11	60,524,475 (GRCm38)	missense	probably damaging	1.00
R6882:Myo15a	UTSW	11	60,524,006 (GRCm38)	missense	probably damaging	1.00
R6908:Myo15a	UTSW	11	60,506,006 (GRCm38)	missense	probably damaging	1.00
R6932:Myo15a	UTSW	11	60,499,494 (GRCm38)	missense	probably damaging	1.00
R6958:Myo15a	UTSW	11	60,503,625 (GRCm38)	missense	probably benign	0.07
R7041:Myo15a	UTSW	11	60,506,006 (GRCm38)	missense	probably damaging	1.00
R7149:Myo15a	UTSW	11	60,510,010 (GRCm38)	missense	possibly damaging	0.56
R7163:Myo15a	UTSW	11	60,498,369 (GRCm38)	missense
R7229:Myo15a	UTSW	11	60,496,495 (GRCm38)	missense	probably benign	0.08
R7347:Myo15a	UTSW	11	60,477,961 (GRCm38)	missense	probably benign
R7392:Myo15a	UTSW	11	60,505,976 (GRCm38)	missense
R7414:Myo15a	UTSW	11	60,483,483 (GRCm38)	missense
R7461:Myo15a	UTSW	11	60,505,152 (GRCm38)	missense
R7609:Myo15a	UTSW	11	60,488,811 (GRCm38)	missense
R7613:Myo15a	UTSW	11	60,505,152 (GRCm38)	missense
R7734:Myo15a	UTSW	11	60,510,282 (GRCm38)	missense	probably benign
R7748:Myo15a	UTSW	11	60,504,901 (GRCm38)	missense
R7767:Myo15a	UTSW	11	60,502,096 (GRCm38)	missense
R7769:Myo15a	UTSW	11	60,509,149 (GRCm38)	missense
R7894:Myo15a	UTSW	11	60,491,137 (GRCm38)	missense
R7919:Myo15a	UTSW	11	60,526,530 (GRCm38)	missense	probably damaging	1.00
R8100:Myo15a	UTSW	11	60,517,190 (GRCm38)	missense	probably damaging	1.00
R8124:Myo15a	UTSW	11	60,507,453 (GRCm38)	missense
R8129:Myo15a	UTSW	11	60,508,200 (GRCm38)	missense
R8428:Myo15a	UTSW	11	60,496,415 (GRCm38)	missense	probably damaging	1.00
R8706:Myo15a	UTSW	11	60,479,617 (GRCm38)	missense	probably benign
R8735:Myo15a	UTSW	11	60,510,853 (GRCm38)	critical splice acceptor site	probably null
R8739:Myo15a	UTSW	11	60,477,262 (GRCm38)	missense	probably benign	0.06
R8790:Myo15a	UTSW	11	60,487,221 (GRCm38)	missense
R8790:Myo15a	UTSW	11	60,476,536 (GRCm38)	missense	possibly damaging	0.73
R8822:Myo15a	UTSW	11	60,476,914 (GRCm38)	missense	probably damaging	0.99
R8907:Myo15a	UTSW	11	60,526,608 (GRCm38)	missense
R8931:Myo15a	UTSW	11	60,477,194 (GRCm38)	missense	probably benign
R9061:Myo15a	UTSW	11	60,502,866 (GRCm38)	missense
R9124:Myo15a	UTSW	11	60,479,126 (GRCm38)	missense	probably benign	0.37
R9297:Myo15a	UTSW	11	60,495,073 (GRCm38)	missense	probably null
R9347:Myo15a	UTSW	11	60,483,729 (GRCm38)	missense
R9417:Myo15a	UTSW	11	60,487,417 (GRCm38)	missense
R9456:Myo15a	UTSW	11	60,501,842 (GRCm38)	missense
R9460:Myo15a	UTSW	11	60,481,740 (GRCm38)	critical splice donor site	probably null
R9615:Myo15a	UTSW	11	60,483,494 (GRCm38)	missense
R9630:Myo15a	UTSW	11	60,517,162 (GRCm38)	missense	probably damaging	1.00
R9746:Myo15a	UTSW	11	60,487,408 (GRCm38)	nonsense	probably null
X0021:Myo15a	UTSW	11	60,482,359 (GRCm38)	nonsense	probably null
X0066:Myo15a	UTSW	11	60,478,220 (GRCm38)	missense	probably damaging	1.00
X0067:Myo15a	UTSW	11	60,478,618 (GRCm38)	missense	possibly damaging	0.88
Z1176:Myo15a	UTSW	11	60,498,403 (GRCm38)	missense
Z1176:Myo15a	UTSW	11	60,488,258 (GRCm38)	missense
Z1176:Myo15a	UTSW	11	60,524,441 (GRCm38)	missense	probably damaging	1.00
Z1177:Myo15a	UTSW	11	60,495,475 (GRCm38)	missense
Z1177:Myo15a	UTSW	11	60,488,837 (GRCm38)	missense
Z1177:Myo15a	UTSW	11	60,477,523 (GRCm38)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- TTCTAGTGGGCATCATCTATCTG -3'
(R):5'- AAGGTGATAGCCTTCTGCAGG -3'

Sequencing Primer
(F):5'- GGGCATCATCTATCTGTAGTACACG -3'
(R):5'- GAGACCTGAAGCAGCTCTG -3'

Posted On

2019-10-28