Incidental Mutation 'R7658:Nup210l'
| ID |
591320 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nup210l
|
| Ensembl Gene |
ENSMUSG00000027939 |
| Gene Name |
nucleoporin 210-like |
| Synonyms |
4930548O11Rik |
| MMRRC Submission |
045703-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.432)
|
| Stock # |
R7658 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
3 |
| Chromosomal Location |
90011439-90119355 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to A
at 90119300 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Histidine to Glutamine
at position 1874
(H1874Q)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000029548
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000029548]
[ENSMUST00000107373]
[ENSMUST00000170122]
[ENSMUST00000195998]
[ENSMUST00000196205]
[ENSMUST00000197361]
[ENSMUST00000200410]
|
| AlphaFold |
Q9D2F7 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000029548
AA Change: H1874Q
PolyPhen 2
Score 0.430 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000029548
Gene: ENSMUSG00000027939
AA Change: H1874Q
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
13 |
32 |
N/A |
INTRINSIC |
|
BID_2
|
457 |
536 |
2.05e1 |
SMART |
|
Blast:S1
|
949 |
1023 |
2e-16 |
BLAST |
|
BID_2
|
1077 |
1152 |
4.51e-11 |
SMART |
|
Blast:BID_2
|
1468 |
1550 |
7e-15 |
BLAST |
|
transmembrane domain
|
1807 |
1829 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000107373
|
| SMART Domains |
Protein: ENSMUSP00000102996
Gene: ENSMUSG00000027935
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Miro
|
1 |
43 |
3.5e-6 |
PFAM |
|
Pfam:Arf
|
1 |
88 |
1.8e-5 |
PFAM |
|
Pfam:Ras
|
1 |
90 |
2.5e-30 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000170122
|
| SMART Domains |
Protein: ENSMUSP00000132102
Gene: ENSMUSG00000090733
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
13 |
23 |
N/A |
INTRINSIC |
|
Pfam:Ribosomal_S27e
|
28 |
82 |
9.8e-34 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000195998
|
| SMART Domains |
Protein: ENSMUSP00000142942
Gene: ENSMUSG00000090733
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Ribosomal_S27e
|
1 |
50 |
3e-30 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000196205
|
| SMART Domains |
Protein: ENSMUSP00000142536
Gene: ENSMUSG00000090733
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
11 |
21 |
N/A |
INTRINSIC |
|
Pfam:Ribosomal_S27e
|
26 |
80 |
7.5e-34 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000197361
|
| SMART Domains |
Protein: ENSMUSP00000143402
Gene: ENSMUSG00000090733
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
13 |
23 |
N/A |
INTRINSIC |
|
Pfam:Ribosomal_S27e
|
28 |
80 |
5.7e-28 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000200410
AA Change: H1874Q
PolyPhen 2
Score 0.430 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000143368
Gene: ENSMUSG00000027939
AA Change: H1874Q
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
32 |
N/A |
INTRINSIC |
|
BID_2
|
457 |
536 |
6.9e-2 |
SMART |
|
Blast:S1
|
938 |
1023 |
9e-17 |
BLAST |
|
BID_2
|
1077 |
1152 |
1.5e-13 |
SMART |
|
Blast:BID_2
|
1468 |
1550 |
7e-15 |
BLAST |
|
transmembrane domain
|
1807 |
1829 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.9%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a transgene insertion exhibit male infertility, asthenozoospermia, teratozoospermia, azoospermia, and seminiferous tubule degeneration. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 95 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1110025L11Rik |
G |
T |
16: 88,860,618 (GRCm39) |
S72Y |
unknown |
Het |
| Abca8b |
T |
A |
11: 109,826,543 (GRCm39) |
K1568N |
probably benign |
Het |
| Adcy6 |
T |
A |
15: 98,493,948 (GRCm39) |
Y865F |
probably benign |
Het |
| Adgrf3 |
A |
T |
5: 30,402,204 (GRCm39) |
V608D |
probably benign |
Het |
| Agbl1 |
G |
T |
7: 76,416,117 (GRCm39) |
A965S |
unknown |
Het |
| Agbl3 |
C |
T |
6: 34,809,443 (GRCm39) |
P690L |
probably benign |
Het |
| Akap9 |
C |
G |
5: 4,018,745 (GRCm39) |
H1109D |
probably benign |
Het |
| Amt |
A |
C |
9: 108,174,430 (GRCm39) |
H65P |
probably damaging |
Het |
| Ankrd11 |
T |
A |
8: 123,620,403 (GRCm39) |
T1150S |
probably benign |
Het |
| Arhgap15 |
A |
C |
2: 44,032,280 (GRCm39) |
H288P |
probably benign |
Het |
| Arhgap39 |
A |
T |
15: 76,621,617 (GRCm39) |
M328K |
probably benign |
Het |
| Arhgef12 |
T |
C |
9: 42,903,832 (GRCm39) |
K743R |
probably damaging |
Het |
| Atg2a |
T |
G |
19: 6,301,293 (GRCm39) |
V789G |
probably damaging |
Het |
| Ccdc54 |
T |
C |
16: 50,410,844 (GRCm39) |
T141A |
probably benign |
Het |
| Ccng2 |
C |
G |
5: 93,421,202 (GRCm39) |
S237R |
probably benign |
Het |
| Cdh5 |
T |
C |
8: 104,856,033 (GRCm39) |
|
probably null |
Het |
| Cdkl3 |
T |
C |
11: 51,918,009 (GRCm39) |
V404A |
not run |
Het |
| Chrm2 |
A |
T |
6: 36,500,184 (GRCm39) |
I14F |
probably benign |
Het |
| Cnbp |
T |
C |
6: 87,822,258 (GRCm39) |
K89E |
possibly damaging |
Het |
| Cntn6 |
T |
A |
6: 104,627,444 (GRCm39) |
D92E |
probably benign |
Het |
| Col15a1 |
T |
C |
4: 47,245,591 (GRCm39) |
F114S |
possibly damaging |
Het |
| Csrnp1 |
A |
G |
9: 119,801,469 (GRCm39) |
F530S |
probably benign |
Het |
| Dcun1d3 |
C |
T |
7: 119,456,891 (GRCm39) |
V274M |
probably damaging |
Het |
| Dph2 |
T |
A |
4: 117,747,478 (GRCm39) |
H302L |
possibly damaging |
Het |
| Fam162a |
A |
T |
16: 35,866,770 (GRCm39) |
Y118* |
probably null |
Het |
| Fam186a |
A |
G |
15: 99,837,725 (GRCm39) |
Y2840H |
unknown |
Het |
| Fto |
A |
G |
8: 92,392,950 (GRCm39) |
K466E |
probably benign |
Het |
| Gal |
T |
A |
19: 3,463,309 (GRCm39) |
Y41F |
probably damaging |
Het |
| Gigyf2 |
A |
T |
1: 87,346,860 (GRCm39) |
L620F |
unknown |
Het |
| Git2 |
C |
T |
5: 114,904,550 (GRCm39) |
R123H |
probably damaging |
Het |
| Glud1 |
A |
T |
14: 34,033,114 (GRCm39) |
E87V |
probably benign |
Het |
| Gm21190 |
T |
G |
5: 15,732,923 (GRCm39) |
E94A |
possibly damaging |
Het |
| Gm5592 |
T |
C |
7: 40,938,134 (GRCm39) |
V472A |
probably benign |
Het |
| Gpc5 |
T |
A |
14: 115,665,620 (GRCm39) |
N481K |
possibly damaging |
Het |
| Gpn2 |
A |
G |
4: 133,318,687 (GRCm39) |
E304G |
probably benign |
Het |
| Gsdmc2 |
T |
C |
15: 63,696,903 (GRCm39) |
T423A |
probably damaging |
Het |
| Gucy2e |
G |
A |
11: 69,117,055 (GRCm39) |
Q789* |
probably null |
Het |
| Gxylt2 |
T |
A |
6: 100,760,104 (GRCm39) |
V213E |
probably damaging |
Het |
| Ighv1-75 |
G |
A |
12: 115,797,731 (GRCm39) |
L64F |
possibly damaging |
Het |
| Il17re |
T |
C |
6: 113,435,943 (GRCm39) |
C30R |
probably benign |
Het |
| Il7 |
G |
T |
3: 7,669,142 (GRCm39) |
D31E |
probably benign |
Het |
| Ints4 |
T |
C |
7: 97,178,460 (GRCm39) |
Y687H |
possibly damaging |
Het |
| Kdelr1 |
T |
G |
7: 45,532,401 (GRCm39) |
V202G |
probably benign |
Het |
| Khnyn |
C |
A |
14: 56,124,596 (GRCm39) |
Y283* |
probably null |
Het |
| Klf11 |
T |
C |
12: 24,703,670 (GRCm39) |
V52A |
probably damaging |
Het |
| Klhl7 |
A |
G |
5: 24,346,284 (GRCm39) |
N310S |
probably benign |
Het |
| Krt27 |
A |
T |
11: 99,240,312 (GRCm39) |
L202Q |
possibly damaging |
Het |
| Lce1d |
A |
G |
3: 92,593,354 (GRCm39) |
C20R |
unknown |
Het |
| Lim2 |
A |
T |
7: 43,083,054 (GRCm39) |
I80F |
possibly damaging |
Het |
| Lrrk2 |
T |
A |
15: 91,584,561 (GRCm39) |
F326Y |
possibly damaging |
Het |
| Lyst |
A |
T |
13: 13,905,061 (GRCm39) |
Y3246F |
possibly damaging |
Het |
| Mafb |
T |
A |
2: 160,208,355 (GRCm39) |
H81L |
possibly damaging |
Het |
| Mfsd5 |
G |
A |
15: 102,189,312 (GRCm39) |
R228H |
probably benign |
Het |
| Mmp1b |
A |
T |
9: 7,386,675 (GRCm39) |
F150I |
possibly damaging |
Het |
| Mthfd1 |
T |
A |
12: 76,317,209 (GRCm39) |
L20Q |
probably damaging |
Het |
| Mxra8 |
A |
G |
4: 155,927,420 (GRCm39) |
T402A |
probably benign |
Het |
| Ndc80 |
A |
T |
17: 71,815,658 (GRCm39) |
L376M |
probably damaging |
Het |
| Nsd1 |
A |
T |
13: 55,425,452 (GRCm39) |
R1536S |
probably damaging |
Het |
| Nyap1 |
T |
C |
5: 137,731,236 (GRCm39) |
H776R |
probably benign |
Het |
| Patj |
C |
A |
4: 98,576,416 (GRCm39) |
H1773Q |
probably damaging |
Het |
| Pax8 |
T |
A |
2: 24,326,523 (GRCm39) |
T280S |
probably benign |
Het |
| Pcdhb19 |
A |
G |
18: 37,632,034 (GRCm39) |
T610A |
probably damaging |
Het |
| Pde2a |
A |
G |
7: 101,160,788 (GRCm39) |
D919G |
possibly damaging |
Het |
| Pdk2 |
T |
A |
11: 94,919,791 (GRCm39) |
Y240F |
probably damaging |
Het |
| Peg3 |
A |
T |
7: 6,712,609 (GRCm39) |
I871N |
probably damaging |
Het |
| Pex1 |
A |
T |
5: 3,646,244 (GRCm39) |
|
probably benign |
Het |
| Pgm2l1 |
C |
T |
7: 99,899,535 (GRCm39) |
R50W |
probably damaging |
Het |
| Phkg1 |
T |
A |
5: 129,894,764 (GRCm39) |
K262N |
probably damaging |
Het |
| Pik3r4 |
A |
G |
9: 105,521,710 (GRCm39) |
E92G |
probably damaging |
Het |
| Prmt6 |
A |
T |
3: 110,157,701 (GRCm39) |
V196E |
possibly damaging |
Het |
| Ptprn2 |
T |
G |
12: 116,685,739 (GRCm39) |
M66R |
probably benign |
Het |
| Rai14 |
C |
T |
15: 10,593,189 (GRCm39) |
G152R |
probably damaging |
Het |
| Recql5 |
A |
T |
11: 115,814,102 (GRCm39) |
S348T |
probably damaging |
Het |
| Rfk |
T |
G |
19: 17,376,046 (GRCm39) |
|
probably null |
Het |
| Ro60 |
T |
C |
1: 143,646,611 (GRCm39) |
T45A |
probably damaging |
Het |
| Selenbp1 |
A |
T |
3: 94,851,413 (GRCm39) |
M389L |
probably benign |
Het |
| Sipa1l2 |
G |
A |
8: 126,219,029 (GRCm39) |
R103C |
probably benign |
Het |
| Slc10a6 |
T |
A |
5: 103,777,056 (GRCm39) |
S15C |
probably damaging |
Het |
| Slc12a2 |
G |
T |
18: 58,065,596 (GRCm39) |
V944L |
probably benign |
Het |
| Slc16a11 |
T |
A |
11: 70,106,143 (GRCm39) |
L127Q |
possibly damaging |
Het |
| Spef1l |
T |
C |
7: 139,556,531 (GRCm39) |
N152S |
probably benign |
Het |
| St6gal1 |
A |
G |
16: 23,174,978 (GRCm39) |
Y272C |
probably damaging |
Het |
| Stab2 |
C |
A |
10: 86,816,999 (GRCm39) |
V133F |
probably benign |
Het |
| Stradb |
G |
A |
1: 59,031,885 (GRCm39) |
V266I |
probably damaging |
Het |
| Tmem150b |
A |
G |
7: 4,723,758 (GRCm39) |
W140R |
probably benign |
Het |
| Tnnt3 |
A |
T |
7: 142,065,833 (GRCm39) |
K157* |
probably null |
Het |
| Ttn |
T |
G |
2: 76,554,113 (GRCm39) |
K30863N |
probably damaging |
Het |
| Vldlr |
G |
A |
19: 27,220,536 (GRCm39) |
R592H |
probably benign |
Het |
| Vmn1r12 |
A |
T |
6: 57,135,883 (GRCm39) |
|
probably benign |
Het |
| Vmn2r63 |
A |
C |
7: 42,574,693 (GRCm39) |
S519R |
probably damaging |
Het |
| Zbtb22 |
G |
C |
17: 34,137,471 (GRCm39) |
E539Q |
probably damaging |
Het |
| Zbtb44 |
G |
A |
9: 30,965,375 (GRCm39) |
A262T |
probably benign |
Het |
| Zfp280d |
A |
T |
9: 72,231,354 (GRCm39) |
N455I |
probably damaging |
Het |
| Zfp287 |
T |
C |
11: 62,616,089 (GRCm39) |
N201D |
probably damaging |
Het |
| Zfp988 |
T |
C |
4: 147,416,751 (GRCm39) |
L395P |
probably damaging |
Het |
|
| Other mutations in Nup210l |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00780:Nup210l
|
APN |
3 |
90,098,156 (GRCm39) |
splice site |
probably benign |
|
|
IGL00813:Nup210l
|
APN |
3 |
90,039,725 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01375:Nup210l
|
APN |
3 |
90,067,200 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01731:Nup210l
|
APN |
3 |
90,061,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01786:Nup210l
|
APN |
3 |
90,030,083 (GRCm39) |
nonsense |
probably null |
|
|
IGL01958:Nup210l
|
APN |
3 |
90,111,231 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
IGL02094:Nup210l
|
APN |
3 |
90,087,520 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02120:Nup210l
|
APN |
3 |
90,044,169 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02313:Nup210l
|
APN |
3 |
90,030,099 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02336:Nup210l
|
APN |
3 |
90,088,859 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02348:Nup210l
|
APN |
3 |
90,011,471 (GRCm39) |
utr 5 prime |
probably benign |
|
|
IGL02372:Nup210l
|
APN |
3 |
90,109,278 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
IGL02557:Nup210l
|
APN |
3 |
90,031,537 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02559:Nup210l
|
APN |
3 |
90,067,260 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02738:Nup210l
|
APN |
3 |
90,044,157 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
IGL03231:Nup210l
|
APN |
3 |
90,096,852 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03257:Nup210l
|
APN |
3 |
90,087,455 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL03388:Nup210l
|
APN |
3 |
90,077,351 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03134:Nup210l
|
UTSW |
3 |
90,098,194 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R0003:Nup210l
|
UTSW |
3 |
90,027,218 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0040:Nup210l
|
UTSW |
3 |
90,089,212 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0083:Nup210l
|
UTSW |
3 |
90,096,882 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0090:Nup210l
|
UTSW |
3 |
90,119,086 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0108:Nup210l
|
UTSW |
3 |
90,096,882 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0142:Nup210l
|
UTSW |
3 |
90,079,420 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0306:Nup210l
|
UTSW |
3 |
90,114,675 (GRCm39) |
missense |
probably benign |
0.13 |
|
R0332:Nup210l
|
UTSW |
3 |
90,039,616 (GRCm39) |
splice site |
probably benign |
|
|
R0346:Nup210l
|
UTSW |
3 |
90,096,745 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0463:Nup210l
|
UTSW |
3 |
90,087,518 (GRCm39) |
missense |
probably null |
1.00 |
|
R0622:Nup210l
|
UTSW |
3 |
90,075,047 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0765:Nup210l
|
UTSW |
3 |
90,027,184 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0990:Nup210l
|
UTSW |
3 |
90,119,232 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1014:Nup210l
|
UTSW |
3 |
90,077,355 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R1036:Nup210l
|
UTSW |
3 |
90,100,247 (GRCm39) |
splice site |
probably benign |
|
|
R1177:Nup210l
|
UTSW |
3 |
90,109,310 (GRCm39) |
missense |
probably benign |
0.11 |
|
R1183:Nup210l
|
UTSW |
3 |
90,067,252 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1188:Nup210l
|
UTSW |
3 |
90,105,486 (GRCm39) |
missense |
probably benign |
0.16 |
|
R1457:Nup210l
|
UTSW |
3 |
90,098,279 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R1471:Nup210l
|
UTSW |
3 |
90,077,869 (GRCm39) |
missense |
probably benign |
|
|
R1627:Nup210l
|
UTSW |
3 |
90,051,476 (GRCm39) |
missense |
probably benign |
0.15 |
|
R1778:Nup210l
|
UTSW |
3 |
90,096,793 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1827:Nup210l
|
UTSW |
3 |
90,061,864 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1843:Nup210l
|
UTSW |
3 |
90,079,393 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1858:Nup210l
|
UTSW |
3 |
90,061,806 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1942:Nup210l
|
UTSW |
3 |
90,058,544 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2015:Nup210l
|
UTSW |
3 |
90,092,739 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2113:Nup210l
|
UTSW |
3 |
90,098,281 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R2944:Nup210l
|
UTSW |
3 |
90,088,852 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3736:Nup210l
|
UTSW |
3 |
90,027,320 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3740:Nup210l
|
UTSW |
3 |
90,114,701 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3741:Nup210l
|
UTSW |
3 |
90,114,701 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3742:Nup210l
|
UTSW |
3 |
90,114,701 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3771:Nup210l
|
UTSW |
3 |
90,027,201 (GRCm39) |
nonsense |
probably null |
|
|
R3773:Nup210l
|
UTSW |
3 |
90,027,201 (GRCm39) |
nonsense |
probably null |
|
|
R3879:Nup210l
|
UTSW |
3 |
90,092,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3882:Nup210l
|
UTSW |
3 |
90,031,517 (GRCm39) |
missense |
probably benign |
0.19 |
|
R3953:Nup210l
|
UTSW |
3 |
90,100,361 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R3954:Nup210l
|
UTSW |
3 |
90,100,361 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R3955:Nup210l
|
UTSW |
3 |
90,100,361 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R3956:Nup210l
|
UTSW |
3 |
90,100,361 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R4200:Nup210l
|
UTSW |
3 |
90,027,218 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4290:Nup210l
|
UTSW |
3 |
90,114,633 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4328:Nup210l
|
UTSW |
3 |
90,083,142 (GRCm39) |
splice site |
probably null |
|
|
R4629:Nup210l
|
UTSW |
3 |
90,098,181 (GRCm39) |
nonsense |
probably null |
|
|
R4629:Nup210l
|
UTSW |
3 |
90,075,182 (GRCm39) |
missense |
probably benign |
0.21 |
|
R4897:Nup210l
|
UTSW |
3 |
90,100,378 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4906:Nup210l
|
UTSW |
3 |
90,077,337 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4966:Nup210l
|
UTSW |
3 |
90,014,208 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5004:Nup210l
|
UTSW |
3 |
90,087,472 (GRCm39) |
nonsense |
probably null |
|
|
R5237:Nup210l
|
UTSW |
3 |
90,087,505 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5499:Nup210l
|
UTSW |
3 |
90,081,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5522:Nup210l
|
UTSW |
3 |
90,061,972 (GRCm39) |
missense |
probably benign |
0.10 |
|
R5627:Nup210l
|
UTSW |
3 |
90,051,557 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5678:Nup210l
|
UTSW |
3 |
90,098,266 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5726:Nup210l
|
UTSW |
3 |
90,036,514 (GRCm39) |
splice site |
probably null |
|
|
R5792:Nup210l
|
UTSW |
3 |
90,107,164 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6129:Nup210l
|
UTSW |
3 |
90,011,483 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6272:Nup210l
|
UTSW |
3 |
90,077,331 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R6290:Nup210l
|
UTSW |
3 |
90,027,216 (GRCm39) |
nonsense |
probably null |
|
|
R6293:Nup210l
|
UTSW |
3 |
90,022,371 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6446:Nup210l
|
UTSW |
3 |
90,079,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6698:Nup210l
|
UTSW |
3 |
90,089,815 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R6855:Nup210l
|
UTSW |
3 |
90,044,231 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6895:Nup210l
|
UTSW |
3 |
90,067,231 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6899:Nup210l
|
UTSW |
3 |
90,075,204 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R6978:Nup210l
|
UTSW |
3 |
90,061,873 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R6980:Nup210l
|
UTSW |
3 |
90,027,234 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7038:Nup210l
|
UTSW |
3 |
90,067,254 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7273:Nup210l
|
UTSW |
3 |
90,025,854 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7450:Nup210l
|
UTSW |
3 |
90,022,495 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7514:Nup210l
|
UTSW |
3 |
90,117,766 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7735:Nup210l
|
UTSW |
3 |
90,092,883 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7772:Nup210l
|
UTSW |
3 |
90,067,233 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7800:Nup210l
|
UTSW |
3 |
90,041,904 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7840:Nup210l
|
UTSW |
3 |
90,030,036 (GRCm39) |
missense |
probably benign |
0.08 |
|
R7847:Nup210l
|
UTSW |
3 |
90,058,430 (GRCm39) |
missense |
probably benign |
|
|
R7848:Nup210l
|
UTSW |
3 |
90,111,212 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8084:Nup210l
|
UTSW |
3 |
90,043,365 (GRCm39) |
missense |
probably benign |
0.15 |
|
R8121:Nup210l
|
UTSW |
3 |
90,022,428 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8421:Nup210l
|
UTSW |
3 |
90,111,174 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8458:Nup210l
|
UTSW |
3 |
90,092,874 (GRCm39) |
missense |
probably null |
1.00 |
|
R8701:Nup210l
|
UTSW |
3 |
90,030,121 (GRCm39) |
missense |
probably benign |
0.41 |
|
R8720:Nup210l
|
UTSW |
3 |
90,117,681 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8770:Nup210l
|
UTSW |
3 |
90,025,850 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8896:Nup210l
|
UTSW |
3 |
90,025,932 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9033:Nup210l
|
UTSW |
3 |
90,105,396 (GRCm39) |
missense |
probably benign |
|
|
R9371:Nup210l
|
UTSW |
3 |
90,107,173 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9373:Nup210l
|
UTSW |
3 |
90,107,173 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9381:Nup210l
|
UTSW |
3 |
90,107,173 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9426:Nup210l
|
UTSW |
3 |
90,107,173 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9427:Nup210l
|
UTSW |
3 |
90,107,173 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9501:Nup210l
|
UTSW |
3 |
90,107,173 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9523:Nup210l
|
UTSW |
3 |
90,107,173 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9574:Nup210l
|
UTSW |
3 |
90,117,693 (GRCm39) |
missense |
probably benign |
|
|
R9612:Nup210l
|
UTSW |
3 |
90,107,173 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9654:Nup210l
|
UTSW |
3 |
90,107,173 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9660:Nup210l
|
UTSW |
3 |
90,107,173 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9660:Nup210l
|
UTSW |
3 |
90,105,402 (GRCm39) |
missense |
probably benign |
0.30 |
|
R9662:Nup210l
|
UTSW |
3 |
90,107,173 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9682:Nup210l
|
UTSW |
3 |
90,051,469 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R9729:Nup210l
|
UTSW |
3 |
90,107,173 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9750:Nup210l
|
UTSW |
3 |
90,117,659 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TTCCAGTTGTTTATGTGCCAAC -3'
(R):5'- GGGAATCCAGCCTCAGAAATG -3'
Sequencing Primer
(F):5'- GTTTATGTGCCAACAACAGGAAC -3'
(R):5'- GGGAATCCAGCCTCAGAAATGTAATC -3'
|
| Posted On |
2019-11-12 |
Incidental Mutation