Incidental Mutation 'R7662:Dennd4a'
| ID |
591646 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dennd4a
|
| Ensembl Gene |
ENSMUSG00000053641 |
| Gene Name |
DENN/MADD domain containing 4A |
| Synonyms |
F730015K02Rik |
| MMRRC Submission |
045737-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.432)
|
| Stock # |
R7662 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
9 |
| Chromosomal Location |
64811340-64919667 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 64852431 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Valine
at position 273
(I273V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000037915
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000038890]
|
| AlphaFold |
E9Q8V6 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000038890
AA Change: I273V
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000037915
Gene: ENSMUSG00000053641
AA Change: I273V
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_1
|
45 |
93 |
3.26e-5 |
PROSPERO |
|
uDENN
|
169 |
276 |
1.71e-28 |
SMART |
|
DENN
|
309 |
493 |
2.4e-73 |
SMART |
|
dDENN
|
559 |
633 |
4.15e-27 |
SMART |
|
low complexity region
|
724 |
735 |
N/A |
INTRINSIC |
|
low complexity region
|
936 |
950 |
N/A |
INTRINSIC |
|
low complexity region
|
1176 |
1191 |
N/A |
INTRINSIC |
|
low complexity region
|
1249 |
1262 |
N/A |
INTRINSIC |
|
low complexity region
|
1402 |
1417 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.1517 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.4%
|
| Validation Efficiency |
100% (82/82) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a DENN domain-containing protein that may function as a guanine nucleotide exchange factor that specifically activates ras-related protein Rab-10. This protein also contains a interferon stimulated response element-binding domain and may be involved in regulating the v-myc avian myelocytomatosis viral (MYC) oncogene. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8. [provided by RefSeq, Mar 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 84 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930504O13Rik |
T |
C |
11: 58,447,443 (GRCm38) |
N41S |
probably benign |
Het |
| 4930563M21Rik |
G |
A |
9: 55,978,715 (GRCm38) |
S48L |
probably benign |
Het |
| 5830411N06Rik |
T |
C |
7: 140,294,812 (GRCm38) |
V401A |
possibly damaging |
Het |
| Abi3bp |
A |
G |
16: 56,617,323 (GRCm38) |
|
probably null |
Het |
| Adssl1 |
T |
A |
12: 112,639,738 (GRCm38) |
V456E |
probably damaging |
Het |
| Aimp1 |
A |
T |
3: 132,674,066 (GRCm38) |
V105E |
probably benign |
Het |
| Ankrd6 |
G |
A |
4: 32,818,694 (GRCm38) |
R270C |
probably damaging |
Het |
| Arid5b |
C |
T |
10: 68,098,587 (GRCm38) |
G495E |
probably benign |
Het |
| Armh1 |
C |
A |
4: 117,213,741 (GRCm38) |
A396S |
probably benign |
Het |
| Asb15 |
T |
A |
6: 24,566,090 (GRCm38) |
D347E |
probably benign |
Het |
| Axin2 |
T |
A |
11: 108,942,456 (GRCm38) |
L489Q |
possibly damaging |
Het |
| Baiap2l1 |
G |
A |
5: 144,357,890 (GRCm38) |
|
probably benign |
Het |
| BC003331 |
T |
C |
1: 150,382,294 (GRCm38) |
S197G |
probably benign |
Het |
| Cdc6 |
T |
C |
11: 98,917,010 (GRCm38) |
L443P |
probably benign |
Het |
| Cdc6 |
T |
A |
11: 98,910,612 (GRCm38) |
N194K |
possibly damaging |
Het |
| Celf2 |
C |
A |
2: 6,553,917 (GRCm38) |
G393C |
probably damaging |
Het |
| Cep290 |
T |
A |
10: 100,537,803 (GRCm38) |
M1315K |
probably benign |
Het |
| Cntn5 |
A |
T |
9: 9,661,385 (GRCm38) |
M887K |
probably benign |
Het |
| Col17a1 |
T |
C |
19: 47,681,501 (GRCm38) |
I71V |
probably benign |
Het |
| Crot |
T |
C |
5: 8,969,072 (GRCm38) |
M494V |
probably damaging |
Het |
| Ctnna2 |
A |
T |
6: 77,636,869 (GRCm38) |
V246D |
probably damaging |
Het |
| Cyb5r4 |
A |
G |
9: 87,027,038 (GRCm38) |
E56G |
possibly damaging |
Het |
| Dennd2a |
A |
G |
6: 39,493,103 (GRCm38) |
Y552H |
probably benign |
Het |
| Dkk2 |
A |
G |
3: 132,177,868 (GRCm38) |
|
probably null |
Het |
| Dnaja2 |
A |
C |
8: 85,539,276 (GRCm38) |
D393E |
probably benign |
Het |
| Dscc1 |
T |
A |
15: 55,076,165 (GRCm38) |
I461F |
possibly damaging |
Het |
| Dspp |
A |
T |
5: 104,177,870 (GRCm38) |
S700C |
unknown |
Het |
| Ect2 |
T |
A |
3: 27,131,798 (GRCm38) |
H512L |
probably damaging |
Het |
| Eif1b |
A |
G |
9: 120,494,211 (GRCm38) |
T46A |
possibly damaging |
Het |
| Fam114a2 |
A |
T |
11: 57,507,565 (GRCm38) |
D182E |
probably damaging |
Het |
| Fez1 |
C |
A |
9: 36,870,500 (GRCm38) |
P347H |
probably damaging |
Het |
| Fgd5 |
G |
A |
6: 92,049,931 (GRCm38) |
|
probably null |
Het |
| Flad1 |
T |
A |
3: 89,403,451 (GRCm38) |
I430F |
probably damaging |
Het |
| Gal3st2b |
T |
C |
1: 93,940,892 (GRCm38) |
Y282H |
probably damaging |
Het |
| Gm29106 |
T |
A |
1: 118,199,407 (GRCm38) |
N276K |
possibly damaging |
Het |
| Gm36176 |
C |
A |
10: 77,846,852 (GRCm38) |
S16Y |
unknown |
Het |
| Gm5624 |
T |
C |
14: 44,561,933 (GRCm38) |
R56G |
possibly damaging |
Het |
| Gpatch11 |
A |
C |
17: 78,839,055 (GRCm38) |
Q43P |
probably benign |
Het |
| Gtpbp2 |
A |
G |
17: 46,166,435 (GRCm38) |
T409A |
probably benign |
Het |
| Hmcn2 |
T |
C |
2: 31,382,345 (GRCm38) |
I1279T |
probably benign |
Het |
| Ick |
G |
C |
9: 78,167,620 (GRCm38) |
V586L |
probably benign |
Het |
| Itih3 |
T |
A |
14: 30,917,330 (GRCm38) |
N429Y |
probably benign |
Het |
| Lrp5 |
A |
G |
19: 3,686,353 (GRCm38) |
|
probably null |
Het |
| Lrrc34 |
T |
A |
3: 30,643,303 (GRCm38) |
Y93F |
probably benign |
Het |
| Malrd1 |
T |
A |
2: 15,871,454 (GRCm38) |
V1404D |
unknown |
Het |
| Med1 |
T |
C |
11: 98,155,392 (GRCm38) |
N1526S |
unknown |
Het |
| Myt1l |
A |
G |
12: 29,826,869 (GRCm38) |
D173G |
unknown |
Het |
| Nckap1l |
A |
T |
15: 103,462,585 (GRCm38) |
H197L |
probably damaging |
Het |
| Nipa1 |
T |
C |
7: 55,979,624 (GRCm38) |
E247G |
probably damaging |
Het |
| Nmrk1 |
A |
T |
19: 18,642,178 (GRCm38) |
R132* |
probably null |
Het |
| Nrap |
G |
T |
19: 56,320,283 (GRCm38) |
A1700E |
probably benign |
Het |
| Olfr1340 |
T |
A |
4: 118,726,307 (GRCm38) |
F20Y |
probably damaging |
Het |
| Olfr951 |
A |
T |
9: 39,394,093 (GRCm38) |
M98L |
probably benign |
Het |
| Padi6 |
T |
C |
4: 140,728,995 (GRCm38) |
T563A |
probably benign |
Het |
| Pcdhb19 |
G |
A |
18: 37,498,735 (GRCm38) |
E528K |
probably damaging |
Het |
| Pcnt |
T |
C |
10: 76,387,522 (GRCm38) |
D1942G |
probably benign |
Het |
| Pcnx2 |
C |
T |
8: 125,818,771 (GRCm38) |
W1167* |
probably null |
Het |
| Pkp3 |
C |
T |
7: 141,078,379 (GRCm38) |
T19I |
probably benign |
Het |
| Plekhg5 |
T |
C |
4: 152,104,298 (GRCm38) |
L199P |
probably damaging |
Het |
| Rasal1 |
A |
G |
5: 120,662,184 (GRCm38) |
T171A |
probably benign |
Het |
| Rgsl1 |
T |
C |
1: 153,825,479 (GRCm38) |
I410V |
probably benign |
Het |
| Sftpa1 |
C |
A |
14: 41,134,212 (GRCm38) |
N171K |
probably damaging |
Het |
| Slc5a9 |
A |
T |
4: 111,877,540 (GRCm38) |
*686R |
probably null |
Het |
| Smap1 |
A |
T |
1: 23,877,774 (GRCm38) |
N91K |
probably damaging |
Het |
| Tenm3 |
A |
G |
8: 48,335,727 (GRCm38) |
S695P |
probably benign |
Het |
| Thoc3 |
A |
T |
13: 54,463,804 (GRCm38) |
H223Q |
probably damaging |
Het |
| Tmco4 |
T |
C |
4: 139,010,561 (GRCm38) |
F156L |
probably benign |
Het |
| Tmem30a |
C |
T |
9: 79,775,231 (GRCm38) |
V188I |
probably benign |
Het |
| Trim27 |
T |
A |
13: 21,192,158 (GRCm38) |
C359S |
probably benign |
Het |
| Trrap |
A |
G |
5: 144,832,511 (GRCm38) |
T2609A |
probably benign |
Het |
| Ttn |
A |
G |
2: 76,862,400 (GRCm38) |
V446A |
|
Het |
| Vat1l |
T |
A |
8: 114,282,344 (GRCm38) |
Y273N |
probably damaging |
Het |
| Vmn1r129 |
T |
A |
7: 21,360,627 (GRCm38) |
H222L |
possibly damaging |
Het |
| Vmn2r19 |
A |
G |
6: 123,331,562 (GRCm38) |
T533A |
probably benign |
Het |
| Vmn2r77 |
T |
A |
7: 86,811,284 (GRCm38) |
L606* |
probably null |
Het |
| Vmn2r93 |
G |
T |
17: 18,305,369 (GRCm38) |
V430L |
probably benign |
Het |
| Vps50 |
T |
A |
6: 3,562,304 (GRCm38) |
N466K |
probably damaging |
Het |
| Zfp507 |
A |
T |
7: 35,787,804 (GRCm38) |
Y746* |
probably null |
Het |
| Zfp521 |
A |
C |
18: 13,844,116 (GRCm38) |
L1080R |
probably damaging |
Het |
| Zfp74 |
A |
G |
7: 29,953,853 (GRCm38) |
|
probably null |
Het |
| Zfp831 |
G |
A |
2: 174,646,141 (GRCm38) |
A870T |
possibly damaging |
Het |
| Zfp936 |
A |
T |
7: 43,189,912 (GRCm38) |
K268* |
probably null |
Het |
| Zhx2 |
C |
A |
15: 57,822,176 (GRCm38) |
R314S |
probably damaging |
Het |
| Zkscan16 |
A |
T |
4: 58,957,679 (GRCm38) |
K654* |
probably null |
Het |
|
| Other mutations in Dennd4a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00476:Dennd4a
|
APN |
9 |
64,911,762 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01610:Dennd4a
|
APN |
9 |
64,906,884 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01788:Dennd4a
|
APN |
9 |
64,842,621 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01827:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL01828:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL01829:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL01979:Dennd4a
|
APN |
9 |
64,894,409 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL02100:Dennd4a
|
APN |
9 |
64,909,706 (GRCm38) |
splice site |
probably benign |
|
|
IGL02339:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL02341:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL02584:Dennd4a
|
APN |
9 |
64,851,298 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02607:Dennd4a
|
APN |
9 |
64,862,327 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02654:Dennd4a
|
APN |
9 |
64,910,191 (GRCm38) |
splice site |
probably benign |
|
|
IGL02701:Dennd4a
|
APN |
9 |
64,897,353 (GRCm38) |
missense |
possibly damaging |
0.50 |
|
IGL03051:Dennd4a
|
APN |
9 |
64,862,414 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03257:Dennd4a
|
APN |
9 |
64,871,874 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
IGL03346:Dennd4a
|
APN |
9 |
64,888,526 (GRCm38) |
missense |
possibly damaging |
0.47 |
|
IGL03349:Dennd4a
|
APN |
9 |
64,888,974 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03398:Dennd4a
|
APN |
9 |
64,871,882 (GRCm38) |
missense |
probably benign |
0.32 |
|
R0010:Dennd4a
|
UTSW |
9 |
64,896,715 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0010:Dennd4a
|
UTSW |
9 |
64,896,715 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0129:Dennd4a
|
UTSW |
9 |
64,893,294 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0220:Dennd4a
|
UTSW |
9 |
64,852,445 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0396:Dennd4a
|
UTSW |
9 |
64,862,391 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0881:Dennd4a
|
UTSW |
9 |
64,851,383 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1225:Dennd4a
|
UTSW |
9 |
64,911,675 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1311:Dennd4a
|
UTSW |
9 |
64,910,004 (GRCm38) |
missense |
probably benign |
0.34 |
|
R1448:Dennd4a
|
UTSW |
9 |
64,906,045 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R1450:Dennd4a
|
UTSW |
9 |
64,911,665 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1630:Dennd4a
|
UTSW |
9 |
64,871,882 (GRCm38) |
missense |
probably benign |
0.32 |
|
R1709:Dennd4a
|
UTSW |
9 |
64,889,605 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R1824:Dennd4a
|
UTSW |
9 |
64,859,358 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1851:Dennd4a
|
UTSW |
9 |
64,862,030 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1870:Dennd4a
|
UTSW |
9 |
64,897,234 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1900:Dennd4a
|
UTSW |
9 |
64,897,336 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1911:Dennd4a
|
UTSW |
9 |
64,889,086 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1938:Dennd4a
|
UTSW |
9 |
64,842,490 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1954:Dennd4a
|
UTSW |
9 |
64,852,467 (GRCm38) |
missense |
probably benign |
0.02 |
|
R1955:Dennd4a
|
UTSW |
9 |
64,852,467 (GRCm38) |
missense |
probably benign |
0.02 |
|
R2049:Dennd4a
|
UTSW |
9 |
64,889,605 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R2129:Dennd4a
|
UTSW |
9 |
64,905,974 (GRCm38) |
splice site |
probably null |
|
|
R2138:Dennd4a
|
UTSW |
9 |
64,889,337 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2929:Dennd4a
|
UTSW |
9 |
64,852,417 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R3083:Dennd4a
|
UTSW |
9 |
64,906,081 (GRCm38) |
missense |
probably benign |
0.03 |
|
R3108:Dennd4a
|
UTSW |
9 |
64,912,387 (GRCm38) |
missense |
probably benign |
0.23 |
|
R3176:Dennd4a
|
UTSW |
9 |
64,888,993 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3177:Dennd4a
|
UTSW |
9 |
64,888,993 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3276:Dennd4a
|
UTSW |
9 |
64,888,993 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3277:Dennd4a
|
UTSW |
9 |
64,888,993 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3890:Dennd4a
|
UTSW |
9 |
64,872,028 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3953:Dennd4a
|
UTSW |
9 |
64,852,575 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3963:Dennd4a
|
UTSW |
9 |
64,862,331 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4059:Dennd4a
|
UTSW |
9 |
64,911,892 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R4499:Dennd4a
|
UTSW |
9 |
64,910,123 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R4500:Dennd4a
|
UTSW |
9 |
64,910,123 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R4501:Dennd4a
|
UTSW |
9 |
64,910,123 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R4671:Dennd4a
|
UTSW |
9 |
64,894,407 (GRCm38) |
missense |
probably benign |
|
|
R4701:Dennd4a
|
UTSW |
9 |
64,897,357 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R4821:Dennd4a
|
UTSW |
9 |
64,897,249 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R4829:Dennd4a
|
UTSW |
9 |
64,889,056 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4876:Dennd4a
|
UTSW |
9 |
64,896,590 (GRCm38) |
missense |
probably benign |
|
|
R4881:Dennd4a
|
UTSW |
9 |
64,838,844 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
R4962:Dennd4a
|
UTSW |
9 |
64,906,003 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5225:Dennd4a
|
UTSW |
9 |
64,888,928 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R5557:Dennd4a
|
UTSW |
9 |
64,904,227 (GRCm38) |
missense |
probably benign |
0.07 |
|
R5649:Dennd4a
|
UTSW |
9 |
64,851,209 (GRCm38) |
splice site |
probably null |
|
|
R5868:Dennd4a
|
UTSW |
9 |
64,896,729 (GRCm38) |
missense |
probably benign |
0.02 |
|
R5876:Dennd4a
|
UTSW |
9 |
64,911,755 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6052:Dennd4a
|
UTSW |
9 |
64,886,945 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6411:Dennd4a
|
UTSW |
9 |
64,871,899 (GRCm38) |
missense |
probably benign |
0.04 |
|
R6596:Dennd4a
|
UTSW |
9 |
64,852,420 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6668:Dennd4a
|
UTSW |
9 |
64,886,965 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6915:Dennd4a
|
UTSW |
9 |
64,852,489 (GRCm38) |
nonsense |
probably null |
|
|
R7056:Dennd4a
|
UTSW |
9 |
64,906,923 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R7107:Dennd4a
|
UTSW |
9 |
64,894,399 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R7203:Dennd4a
|
UTSW |
9 |
64,896,474 (GRCm38) |
missense |
probably benign |
0.05 |
|
R7238:Dennd4a
|
UTSW |
9 |
64,861,956 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7373:Dennd4a
|
UTSW |
9 |
64,897,269 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7454:Dennd4a
|
UTSW |
9 |
64,852,570 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7546:Dennd4a
|
UTSW |
9 |
64,873,044 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7590:Dennd4a
|
UTSW |
9 |
64,888,587 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7782:Dennd4a
|
UTSW |
9 |
64,906,920 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R7909:Dennd4a
|
UTSW |
9 |
64,872,993 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R7976:Dennd4a
|
UTSW |
9 |
64,852,512 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R8026:Dennd4a
|
UTSW |
9 |
64,873,030 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8034:Dennd4a
|
UTSW |
9 |
64,888,568 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8089:Dennd4a
|
UTSW |
9 |
64,849,175 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8298:Dennd4a
|
UTSW |
9 |
64,906,875 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8397:Dennd4a
|
UTSW |
9 |
64,889,109 (GRCm38) |
missense |
probably benign |
|
|
R8425:Dennd4a
|
UTSW |
9 |
64,838,974 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8495:Dennd4a
|
UTSW |
9 |
64,886,879 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8855:Dennd4a
|
UTSW |
9 |
64,912,390 (GRCm38) |
missense |
probably benign |
|
|
R9219:Dennd4a
|
UTSW |
9 |
64,889,094 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R9275:Dennd4a
|
UTSW |
9 |
64,842,624 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9376:Dennd4a
|
UTSW |
9 |
64,912,692 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9485:Dennd4a
|
UTSW |
9 |
64,907,106 (GRCm38) |
nonsense |
probably null |
|
|
R9672:Dennd4a
|
UTSW |
9 |
64,893,358 (GRCm38) |
missense |
probably benign |
|
|
R9746:Dennd4a
|
UTSW |
9 |
64,894,511 (GRCm38) |
missense |
probably benign |
|
|
X0026:Dennd4a
|
UTSW |
9 |
64,897,320 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
Z1088:Dennd4a
|
UTSW |
9 |
64,872,022 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TAGCAGATTTATCAAGAAAGCAGTC -3'
(R):5'- CAATTGGAAGGGCATGAGGTCC -3'
Sequencing Primer
(F):5'- TGACAAGTTTGAGGCCAGCC -3'
(R):5'- CATGAGGTCCAGAGATGGAATAAC -3'
|
| Posted On |
2019-11-12 |
Incidental Mutation