Incidental Mutation 'R7662:Med1'
| ID |
591657 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Med1
|
| Ensembl Gene |
ENSMUSG00000018160 |
| Gene Name |
mediator complex subunit 1 |
| Synonyms |
DRIP205, TRAP220, PBP, Pparbp, CRSP210, l11Jus15, TRAP 220 |
| MMRRC Submission |
045737-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R7662 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
98042980-98084119 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 98046218 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Serine
at position 1526
(N1526S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000103169
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000018304]
[ENSMUST00000092735]
[ENSMUST00000107545]
[ENSMUST00000150378]
|
| AlphaFold |
Q925J9 |
| Predicted Effect |
unknown
Transcript: ENSMUST00000018304
AA Change: N1511S
|
| SMART Domains |
Protein: ENSMUSP00000018304
Gene: ENSMUSG00000018160
AA Change: N1511S
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Med1
|
18 |
414 |
3.7e-112 |
PFAM |
|
low complexity region
|
536 |
559 |
N/A |
INTRINSIC |
|
low complexity region
|
595 |
619 |
N/A |
INTRINSIC |
|
low complexity region
|
667 |
678 |
N/A |
INTRINSIC |
|
low complexity region
|
960 |
981 |
N/A |
INTRINSIC |
|
low complexity region
|
989 |
999 |
N/A |
INTRINSIC |
|
low complexity region
|
1015 |
1036 |
N/A |
INTRINSIC |
|
low complexity region
|
1042 |
1054 |
N/A |
INTRINSIC |
|
low complexity region
|
1063 |
1138 |
N/A |
INTRINSIC |
|
low complexity region
|
1170 |
1183 |
N/A |
INTRINSIC |
|
low complexity region
|
1205 |
1243 |
N/A |
INTRINSIC |
|
low complexity region
|
1250 |
1281 |
N/A |
INTRINSIC |
|
low complexity region
|
1344 |
1364 |
N/A |
INTRINSIC |
|
low complexity region
|
1482 |
1503 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000092735
|
| SMART Domains |
Protein: ENSMUSP00000090411
Gene: ENSMUSG00000018160
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Med1
|
33 |
429 |
1.2e-113 |
PFAM |
|
transmembrane domain
|
585 |
607 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000107545
AA Change: N1526S
|
| SMART Domains |
Protein: ENSMUSP00000103169
Gene: ENSMUSG00000018160
AA Change: N1526S
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Med1
|
59 |
426 |
2.9e-74 |
PFAM |
|
low complexity region
|
551 |
574 |
N/A |
INTRINSIC |
|
low complexity region
|
610 |
634 |
N/A |
INTRINSIC |
|
low complexity region
|
682 |
693 |
N/A |
INTRINSIC |
|
low complexity region
|
975 |
996 |
N/A |
INTRINSIC |
|
low complexity region
|
1004 |
1014 |
N/A |
INTRINSIC |
|
low complexity region
|
1030 |
1051 |
N/A |
INTRINSIC |
|
low complexity region
|
1057 |
1069 |
N/A |
INTRINSIC |
|
low complexity region
|
1078 |
1153 |
N/A |
INTRINSIC |
|
low complexity region
|
1185 |
1198 |
N/A |
INTRINSIC |
|
low complexity region
|
1220 |
1258 |
N/A |
INTRINSIC |
|
low complexity region
|
1265 |
1296 |
N/A |
INTRINSIC |
|
low complexity region
|
1359 |
1379 |
N/A |
INTRINSIC |
|
low complexity region
|
1497 |
1518 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000150378
|
| SMART Domains |
Protein: ENSMUSP00000119003
Gene: ENSMUSG00000020883
| Domain | Start | End | E-Value | Type |
|---|
|
FBOX
|
30 |
70 |
2.62e-8 |
SMART |
|
LRR
|
92 |
117 |
3.69e1 |
SMART |
|
LRR
|
121 |
146 |
7.9e-4 |
SMART |
|
LRR_CC
|
147 |
172 |
4.61e-5 |
SMART |
|
LRR
|
173 |
198 |
7.15e-2 |
SMART |
|
| Meta Mutation Damage Score |
0.0869 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.4%
|
| Validation Efficiency |
100% (82/82) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize. [provided by RefSeq, Jul 2008]
PHENOTYPE: Homozygotes for targeted null mutations have defects of placental vasculature, heart, and lens, arrested erythrocytic differentiation, impaired neuronal development, and die by embryonic day 11.5. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 84 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930563M21Rik |
G |
A |
9: 55,885,999 (GRCm39) |
S48L |
probably benign |
Het |
| Abi3bp |
A |
G |
16: 56,437,686 (GRCm39) |
|
probably null |
Het |
| Adss1 |
T |
A |
12: 112,606,172 (GRCm39) |
V456E |
probably damaging |
Het |
| Aimp1 |
A |
T |
3: 132,379,827 (GRCm39) |
V105E |
probably benign |
Het |
| Ankrd6 |
G |
A |
4: 32,818,694 (GRCm39) |
R270C |
probably damaging |
Het |
| Arid5b |
C |
T |
10: 67,934,417 (GRCm39) |
G495E |
probably benign |
Het |
| Armh1 |
C |
A |
4: 117,070,938 (GRCm39) |
A396S |
probably benign |
Het |
| Asb15 |
T |
A |
6: 24,566,089 (GRCm39) |
D347E |
probably benign |
Het |
| Axin2 |
T |
A |
11: 108,833,282 (GRCm39) |
L489Q |
possibly damaging |
Het |
| Baiap2l1 |
G |
A |
5: 144,294,700 (GRCm39) |
|
probably benign |
Het |
| Cdc6 |
T |
A |
11: 98,801,438 (GRCm39) |
N194K |
possibly damaging |
Het |
| Cdc6 |
T |
C |
11: 98,807,836 (GRCm39) |
L443P |
probably benign |
Het |
| Celf2 |
C |
A |
2: 6,558,728 (GRCm39) |
G393C |
probably damaging |
Het |
| Cep290 |
T |
A |
10: 100,373,665 (GRCm39) |
M1315K |
probably benign |
Het |
| Cilk1 |
G |
C |
9: 78,074,902 (GRCm39) |
V586L |
probably benign |
Het |
| Cntn5 |
A |
T |
9: 9,661,390 (GRCm39) |
M887K |
probably benign |
Het |
| Col17a1 |
T |
C |
19: 47,669,940 (GRCm39) |
I71V |
probably benign |
Het |
| Crot |
T |
C |
5: 9,019,072 (GRCm39) |
M494V |
probably damaging |
Het |
| Ctnna2 |
A |
T |
6: 77,613,852 (GRCm39) |
V246D |
probably damaging |
Het |
| Cyb5r4 |
A |
G |
9: 86,909,091 (GRCm39) |
E56G |
possibly damaging |
Het |
| Dennd2a |
A |
G |
6: 39,470,037 (GRCm39) |
Y552H |
probably benign |
Het |
| Dennd4a |
A |
G |
9: 64,759,713 (GRCm39) |
I273V |
probably damaging |
Het |
| Dkk2 |
A |
G |
3: 131,883,629 (GRCm39) |
|
probably null |
Het |
| Dnaja2 |
A |
C |
8: 86,265,905 (GRCm39) |
D393E |
probably benign |
Het |
| Dscc1 |
T |
A |
15: 54,939,561 (GRCm39) |
I461F |
possibly damaging |
Het |
| Dspp |
A |
T |
5: 104,325,736 (GRCm39) |
S700C |
unknown |
Het |
| Ect2 |
T |
A |
3: 27,185,947 (GRCm39) |
H512L |
probably damaging |
Het |
| Eif1b |
A |
G |
9: 120,323,277 (GRCm39) |
T46A |
possibly damaging |
Het |
| Fam114a2 |
A |
T |
11: 57,398,391 (GRCm39) |
D182E |
probably damaging |
Het |
| Fez1 |
C |
A |
9: 36,781,796 (GRCm39) |
P347H |
probably damaging |
Het |
| Fgd5 |
G |
A |
6: 92,026,912 (GRCm39) |
|
probably null |
Het |
| Flad1 |
T |
A |
3: 89,310,758 (GRCm39) |
I430F |
probably damaging |
Het |
| Gal3st2b |
T |
C |
1: 93,868,614 (GRCm39) |
Y282H |
probably damaging |
Het |
| Gm29106 |
T |
A |
1: 118,127,137 (GRCm39) |
N276K |
possibly damaging |
Het |
| Gm36176 |
C |
A |
10: 77,682,686 (GRCm39) |
S16Y |
unknown |
Het |
| Gm5624 |
T |
C |
14: 44,799,390 (GRCm39) |
R56G |
possibly damaging |
Het |
| Gpatch11 |
A |
C |
17: 79,146,484 (GRCm39) |
Q43P |
probably benign |
Het |
| Gtpbp2 |
A |
G |
17: 46,477,361 (GRCm39) |
T409A |
probably benign |
Het |
| Hmcn2 |
T |
C |
2: 31,272,357 (GRCm39) |
I1279T |
probably benign |
Het |
| Itih3 |
T |
A |
14: 30,639,287 (GRCm39) |
N429Y |
probably benign |
Het |
| Lrp5 |
A |
G |
19: 3,736,353 (GRCm39) |
|
probably null |
Het |
| Lrrc34 |
T |
A |
3: 30,697,452 (GRCm39) |
Y93F |
probably benign |
Het |
| Lypd9 |
T |
C |
11: 58,338,269 (GRCm39) |
N41S |
probably benign |
Het |
| Malrd1 |
T |
A |
2: 15,876,265 (GRCm39) |
V1404D |
unknown |
Het |
| Myt1l |
A |
G |
12: 29,876,868 (GRCm39) |
D173G |
unknown |
Het |
| Nckap1l |
A |
T |
15: 103,371,012 (GRCm39) |
H197L |
probably damaging |
Het |
| Nipa1 |
T |
C |
7: 55,629,372 (GRCm39) |
E247G |
probably damaging |
Het |
| Nmrk1 |
A |
T |
19: 18,619,542 (GRCm39) |
R132* |
probably null |
Het |
| Nrap |
G |
T |
19: 56,308,715 (GRCm39) |
A1700E |
probably benign |
Het |
| Odr4 |
T |
C |
1: 150,258,045 (GRCm39) |
S197G |
probably benign |
Het |
| Or13p8 |
T |
A |
4: 118,583,504 (GRCm39) |
F20Y |
probably damaging |
Het |
| Or8g32 |
A |
T |
9: 39,305,389 (GRCm39) |
M98L |
probably benign |
Het |
| Padi6 |
T |
C |
4: 140,456,306 (GRCm39) |
T563A |
probably benign |
Het |
| Pcdhb19 |
G |
A |
18: 37,631,788 (GRCm39) |
E528K |
probably damaging |
Het |
| Pcnt |
T |
C |
10: 76,223,356 (GRCm39) |
D1942G |
probably benign |
Het |
| Pcnx2 |
C |
T |
8: 126,545,510 (GRCm39) |
W1167* |
probably null |
Het |
| Pkp3 |
C |
T |
7: 140,658,292 (GRCm39) |
T19I |
probably benign |
Het |
| Plekhg5 |
T |
C |
4: 152,188,755 (GRCm39) |
L199P |
probably damaging |
Het |
| Rasal1 |
A |
G |
5: 120,800,249 (GRCm39) |
T171A |
probably benign |
Het |
| Rgsl1 |
T |
C |
1: 153,701,225 (GRCm39) |
I410V |
probably benign |
Het |
| Scart2 |
T |
C |
7: 139,874,725 (GRCm39) |
V401A |
possibly damaging |
Het |
| Sftpa1 |
C |
A |
14: 40,856,169 (GRCm39) |
N171K |
probably damaging |
Het |
| Slc5a9 |
A |
T |
4: 111,734,737 (GRCm39) |
*686R |
probably null |
Het |
| Smap1 |
A |
T |
1: 23,916,855 (GRCm39) |
N91K |
probably damaging |
Het |
| Tenm3 |
A |
G |
8: 48,788,762 (GRCm39) |
S695P |
probably benign |
Het |
| Thoc3 |
A |
T |
13: 54,611,617 (GRCm39) |
H223Q |
probably damaging |
Het |
| Tmco4 |
T |
C |
4: 138,737,872 (GRCm39) |
F156L |
probably benign |
Het |
| Tmem30a |
C |
T |
9: 79,682,513 (GRCm39) |
V188I |
probably benign |
Het |
| Trim27 |
T |
A |
13: 21,376,328 (GRCm39) |
C359S |
probably benign |
Het |
| Trrap |
A |
G |
5: 144,769,321 (GRCm39) |
T2609A |
probably benign |
Het |
| Ttn |
A |
G |
2: 76,692,744 (GRCm39) |
V446A |
|
Het |
| Vat1l |
T |
A |
8: 115,009,084 (GRCm39) |
Y273N |
probably damaging |
Het |
| Vmn1r129 |
T |
A |
7: 21,094,552 (GRCm39) |
H222L |
possibly damaging |
Het |
| Vmn2r19 |
A |
G |
6: 123,308,521 (GRCm39) |
T533A |
probably benign |
Het |
| Vmn2r77 |
T |
A |
7: 86,460,492 (GRCm39) |
L606* |
probably null |
Het |
| Vmn2r93 |
G |
T |
17: 18,525,631 (GRCm39) |
V430L |
probably benign |
Het |
| Vps50 |
T |
A |
6: 3,562,304 (GRCm39) |
N466K |
probably damaging |
Het |
| Zfp507 |
A |
T |
7: 35,487,229 (GRCm39) |
Y746* |
probably null |
Het |
| Zfp521 |
A |
C |
18: 13,977,173 (GRCm39) |
L1080R |
probably damaging |
Het |
| Zfp74 |
A |
G |
7: 29,653,278 (GRCm39) |
|
probably null |
Het |
| Zfp831 |
G |
A |
2: 174,487,934 (GRCm39) |
A870T |
possibly damaging |
Het |
| Zfp936 |
A |
T |
7: 42,839,336 (GRCm39) |
K268* |
probably null |
Het |
| Zhx2 |
C |
A |
15: 57,685,572 (GRCm39) |
R314S |
probably damaging |
Het |
| Zkscan16 |
A |
T |
4: 58,957,679 (GRCm39) |
K654* |
probably null |
Het |
|
| Other mutations in Med1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00556:Med1
|
APN |
11 |
98,046,510 (GRCm39) |
intron |
probably benign |
|
|
IGL00690:Med1
|
APN |
11 |
98,060,226 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01087:Med1
|
APN |
11 |
98,071,111 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01133:Med1
|
APN |
11 |
98,048,812 (GRCm39) |
nonsense |
probably null |
|
|
IGL02223:Med1
|
APN |
11 |
98,048,702 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02257:Med1
|
APN |
11 |
98,071,096 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02699:Med1
|
APN |
11 |
98,070,851 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
IGL02706:Med1
|
APN |
11 |
98,047,533 (GRCm39) |
intron |
probably benign |
|
|
IGL02902:Med1
|
APN |
11 |
98,047,335 (GRCm39) |
intron |
probably benign |
|
|
IGL02986:Med1
|
APN |
11 |
98,047,086 (GRCm39) |
intron |
probably benign |
|
|
IGL03011:Med1
|
APN |
11 |
98,051,859 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL03282:Med1
|
APN |
11 |
98,047,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03303:Med1
|
APN |
11 |
98,049,178 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03342:Med1
|
APN |
11 |
98,080,006 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03410:Med1
|
APN |
11 |
98,080,009 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
PIT4453001:Med1
|
UTSW |
11 |
98,049,243 (GRCm39) |
missense |
probably benign |
0.40 |
|
R0040:Med1
|
UTSW |
11 |
98,057,081 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0206:Med1
|
UTSW |
11 |
98,046,515 (GRCm39) |
intron |
probably benign |
|
|
R0206:Med1
|
UTSW |
11 |
98,046,515 (GRCm39) |
intron |
probably benign |
|
|
R0208:Med1
|
UTSW |
11 |
98,046,515 (GRCm39) |
intron |
probably benign |
|
|
R0310:Med1
|
UTSW |
11 |
98,058,400 (GRCm39) |
missense |
probably benign |
0.38 |
|
R0505:Med1
|
UTSW |
11 |
98,047,730 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0597:Med1
|
UTSW |
11 |
98,060,264 (GRCm39) |
missense |
probably benign |
0.08 |
|
R0680:Med1
|
UTSW |
11 |
98,070,992 (GRCm39) |
splice site |
probably null |
|
|
R0686:Med1
|
UTSW |
11 |
98,049,230 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0698:Med1
|
UTSW |
11 |
98,046,515 (GRCm39) |
intron |
probably benign |
|
|
R1293:Med1
|
UTSW |
11 |
98,047,862 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1302:Med1
|
UTSW |
11 |
98,048,275 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R1365:Med1
|
UTSW |
11 |
98,046,821 (GRCm39) |
intron |
probably benign |
|
|
R1537:Med1
|
UTSW |
11 |
98,051,772 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1609:Med1
|
UTSW |
11 |
98,051,996 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R1631:Med1
|
UTSW |
11 |
98,046,452 (GRCm39) |
intron |
probably benign |
|
|
R1792:Med1
|
UTSW |
11 |
98,048,109 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1831:Med1
|
UTSW |
11 |
98,047,437 (GRCm39) |
intron |
probably benign |
|
|
R1837:Med1
|
UTSW |
11 |
98,060,238 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2366:Med1
|
UTSW |
11 |
98,052,008 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3754:Med1
|
UTSW |
11 |
98,057,548 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R3762:Med1
|
UTSW |
11 |
98,046,341 (GRCm39) |
intron |
probably benign |
|
|
R4012:Med1
|
UTSW |
11 |
98,062,532 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R4112:Med1
|
UTSW |
11 |
98,070,913 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4384:Med1
|
UTSW |
11 |
98,043,688 (GRCm39) |
unclassified |
probably benign |
|
|
R4579:Med1
|
UTSW |
11 |
98,049,248 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R4740:Med1
|
UTSW |
11 |
98,071,090 (GRCm39) |
nonsense |
probably null |
|
|
R4819:Med1
|
UTSW |
11 |
98,046,258 (GRCm39) |
intron |
probably benign |
|
|
R4879:Med1
|
UTSW |
11 |
98,046,186 (GRCm39) |
unclassified |
probably benign |
|
|
R4993:Med1
|
UTSW |
11 |
98,054,730 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5040:Med1
|
UTSW |
11 |
98,046,230 (GRCm39) |
intron |
probably benign |
|
|
R5249:Med1
|
UTSW |
11 |
98,048,066 (GRCm39) |
missense |
probably benign |
0.43 |
|
R5373:Med1
|
UTSW |
11 |
98,054,789 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5374:Med1
|
UTSW |
11 |
98,054,789 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5552:Med1
|
UTSW |
11 |
98,057,157 (GRCm39) |
nonsense |
probably null |
|
|
R5692:Med1
|
UTSW |
11 |
98,047,206 (GRCm39) |
intron |
probably benign |
|
|
R6010:Med1
|
UTSW |
11 |
98,049,188 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6149:Med1
|
UTSW |
11 |
98,074,679 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R6417:Med1
|
UTSW |
11 |
98,048,054 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7301:Med1
|
UTSW |
11 |
98,043,634 (GRCm39) |
missense |
probably benign |
0.23 |
|
R7507:Med1
|
UTSW |
11 |
98,048,852 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7529:Med1
|
UTSW |
11 |
98,046,791 (GRCm39) |
missense |
unknown |
|
|
R7588:Med1
|
UTSW |
11 |
98,046,398 (GRCm39) |
missense |
unknown |
|
|
R7654:Med1
|
UTSW |
11 |
98,060,189 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R7679:Med1
|
UTSW |
11 |
98,046,887 (GRCm39) |
missense |
unknown |
|
|
R7862:Med1
|
UTSW |
11 |
98,052,036 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8447:Med1
|
UTSW |
11 |
98,060,240 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8693:Med1
|
UTSW |
11 |
98,046,599 (GRCm39) |
missense |
unknown |
|
|
R8843:Med1
|
UTSW |
11 |
98,080,102 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R9072:Med1
|
UTSW |
11 |
98,080,009 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R9284:Med1
|
UTSW |
11 |
98,046,366 (GRCm39) |
missense |
unknown |
|
|
R9428:Med1
|
UTSW |
11 |
98,080,049 (GRCm39) |
nonsense |
probably null |
|
|
R9465:Med1
|
UTSW |
11 |
98,049,144 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9531:Med1
|
UTSW |
11 |
98,048,321 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9537:Med1
|
UTSW |
11 |
98,062,586 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R9548:Med1
|
UTSW |
11 |
98,070,884 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9680:Med1
|
UTSW |
11 |
98,071,114 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9696:Med1
|
UTSW |
11 |
98,061,772 (GRCm39) |
critical splice donor site |
probably null |
|
|
Z1176:Med1
|
UTSW |
11 |
98,052,009 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
| Predicted Primers |
PCR Primer
(F):5'- CCCTCGGGTTGGTTTACATATATC -3'
(R):5'- ACAGTGAAAGTGAGTCAGGCTC -3'
Sequencing Primer
(F):5'- CCTCTGGACGTGTCTGTTTAGAAAG -3'
(R):5'- AAGTGAGTCAGGCTCCTCCATAG -3'
|
| Posted On |
2019-11-12 |
Incidental Mutation