Incidental Mutation 'R7670:Pcnx3'
| ID |
592136 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pcnx3
|
| Ensembl Gene |
ENSMUSG00000054874 |
| Gene Name |
pecanex homolog 3 |
| Synonyms |
Pcnxl3 |
| MMRRC Submission |
045742-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7670 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
19 |
| Chromosomal Location |
5714663-5738936 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 5727210 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Phenylalanine to Leucine
at position 1108
(F1108L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000109245
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000068169]
[ENSMUST00000113615]
[ENSMUST00000141577]
|
| AlphaFold |
Q8VI59 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000068169
AA Change: F700L
PolyPhen 2
Score 0.009 (Sensitivity: 0.96; Specificity: 0.77)
|
| SMART Domains |
Protein: ENSMUSP00000063786
Gene: ENSMUSG00000054874
AA Change: F700L
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
36 |
53 |
N/A |
INTRINSIC |
|
transmembrane domain
|
57 |
79 |
N/A |
INTRINSIC |
|
low complexity region
|
99 |
111 |
N/A |
INTRINSIC |
|
low complexity region
|
370 |
376 |
N/A |
INTRINSIC |
|
transmembrane domain
|
385 |
407 |
N/A |
INTRINSIC |
|
transmembrane domain
|
411 |
428 |
N/A |
INTRINSIC |
|
transmembrane domain
|
441 |
463 |
N/A |
INTRINSIC |
|
transmembrane domain
|
473 |
492 |
N/A |
INTRINSIC |
|
transmembrane domain
|
501 |
523 |
N/A |
INTRINSIC |
|
transmembrane domain
|
538 |
560 |
N/A |
INTRINSIC |
|
transmembrane domain
|
573 |
592 |
N/A |
INTRINSIC |
|
transmembrane domain
|
645 |
667 |
N/A |
INTRINSIC |
|
transmembrane domain
|
669 |
691 |
N/A |
INTRINSIC |
|
low complexity region
|
1011 |
1025 |
N/A |
INTRINSIC |
|
Pfam:Pecanex_C
|
1159 |
1389 |
7.5e-124 |
PFAM |
|
low complexity region
|
1462 |
1479 |
N/A |
INTRINSIC |
|
low complexity region
|
1481 |
1510 |
N/A |
INTRINSIC |
|
low complexity region
|
1525 |
1538 |
N/A |
INTRINSIC |
|
low complexity region
|
1558 |
1569 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113615
AA Change: F1108L
PolyPhen 2
Score 0.029 (Sensitivity: 0.95; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000109245
Gene: ENSMUSG00000054874
AA Change: F1108L
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
36 |
53 |
N/A |
INTRINSIC |
|
transmembrane domain
|
57 |
79 |
N/A |
INTRINSIC |
|
low complexity region
|
99 |
111 |
N/A |
INTRINSIC |
|
low complexity region
|
438 |
459 |
N/A |
INTRINSIC |
|
low complexity region
|
778 |
784 |
N/A |
INTRINSIC |
|
transmembrane domain
|
793 |
815 |
N/A |
INTRINSIC |
|
transmembrane domain
|
819 |
836 |
N/A |
INTRINSIC |
|
transmembrane domain
|
849 |
871 |
N/A |
INTRINSIC |
|
transmembrane domain
|
881 |
900 |
N/A |
INTRINSIC |
|
transmembrane domain
|
909 |
931 |
N/A |
INTRINSIC |
|
transmembrane domain
|
946 |
968 |
N/A |
INTRINSIC |
|
transmembrane domain
|
981 |
1000 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1053 |
1075 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1077 |
1099 |
N/A |
INTRINSIC |
|
low complexity region
|
1419 |
1433 |
N/A |
INTRINSIC |
|
Pfam:Pecanex_C
|
1570 |
1796 |
5.9e-116 |
PFAM |
|
low complexity region
|
1870 |
1887 |
N/A |
INTRINSIC |
|
low complexity region
|
1889 |
1918 |
N/A |
INTRINSIC |
|
low complexity region
|
1933 |
1946 |
N/A |
INTRINSIC |
|
low complexity region
|
1966 |
1977 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000127876
|
| SMART Domains |
Protein: ENSMUSP00000123696
Gene: ENSMUSG00000054874
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
69 |
75 |
N/A |
INTRINSIC |
|
transmembrane domain
|
84 |
106 |
N/A |
INTRINSIC |
|
transmembrane domain
|
110 |
127 |
N/A |
INTRINSIC |
|
transmembrane domain
|
140 |
162 |
N/A |
INTRINSIC |
|
transmembrane domain
|
172 |
191 |
N/A |
INTRINSIC |
|
transmembrane domain
|
200 |
222 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000137313
|
| SMART Domains |
Protein: ENSMUSP00000115217
Gene: ENSMUSG00000054874
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
23 |
N/A |
INTRINSIC |
|
transmembrane domain
|
44 |
66 |
N/A |
INTRINSIC |
|
transmembrane domain
|
79 |
98 |
N/A |
INTRINSIC |
|
transmembrane domain
|
151 |
173 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000141577
|
| SMART Domains |
Protein: ENSMUSP00000116451
Gene: ENSMUSG00000054874
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
104 |
110 |
N/A |
INTRINSIC |
|
transmembrane domain
|
119 |
141 |
N/A |
INTRINSIC |
|
transmembrane domain
|
145 |
162 |
N/A |
INTRINSIC |
|
transmembrane domain
|
175 |
197 |
N/A |
INTRINSIC |
|
transmembrane domain
|
207 |
224 |
N/A |
INTRINSIC |
|
transmembrane domain
|
229 |
251 |
N/A |
INTRINSIC |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000116493
Gene: ENSMUSG00000054874
AA Change: F528L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
199 |
205 |
N/A |
INTRINSIC |
|
transmembrane domain
|
214 |
236 |
N/A |
INTRINSIC |
|
transmembrane domain
|
240 |
257 |
N/A |
INTRINSIC |
|
transmembrane domain
|
270 |
292 |
N/A |
INTRINSIC |
|
transmembrane domain
|
302 |
321 |
N/A |
INTRINSIC |
|
transmembrane domain
|
330 |
352 |
N/A |
INTRINSIC |
|
transmembrane domain
|
367 |
389 |
N/A |
INTRINSIC |
|
transmembrane domain
|
402 |
421 |
N/A |
INTRINSIC |
|
transmembrane domain
|
474 |
496 |
N/A |
INTRINSIC |
|
transmembrane domain
|
498 |
520 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000146638
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000184789
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000147161
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.4%
|
| Validation Efficiency |
100% (62/62) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 62 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adam26a |
T |
A |
8: 44,023,190 (GRCm39) |
H100L |
probably benign |
Het |
| Adgrf2 |
T |
C |
17: 43,022,263 (GRCm39) |
N187S |
probably damaging |
Het |
| Adipoq |
T |
A |
16: 22,976,332 (GRCm39) |
H244Q |
probably damaging |
Het |
| Arhgap40 |
T |
A |
2: 158,373,845 (GRCm39) |
S209T |
probably benign |
Het |
| Arrdc3 |
C |
T |
13: 81,037,212 (GRCm39) |
L123F |
probably damaging |
Het |
| Aspscr1 |
A |
G |
11: 120,579,865 (GRCm39) |
N212D |
probably benign |
Het |
| Ccr9 |
A |
T |
9: 123,608,371 (GRCm39) |
S18C |
probably damaging |
Het |
| Cdc42bpa |
T |
A |
1: 179,892,646 (GRCm39) |
V270D |
probably damaging |
Het |
| Clic4 |
A |
G |
4: 134,944,516 (GRCm39) |
Y220H |
probably damaging |
Het |
| Cntln |
A |
C |
4: 84,897,577 (GRCm39) |
H388P |
possibly damaging |
Het |
| Col12a1 |
A |
G |
9: 79,538,925 (GRCm39) |
V2457A |
probably damaging |
Het |
| Ctsk |
A |
G |
3: 95,408,925 (GRCm39) |
N103D |
probably benign |
Het |
| Ddx60 |
T |
C |
8: 62,428,826 (GRCm39) |
S779P |
probably damaging |
Het |
| Dnah5 |
T |
A |
15: 28,246,378 (GRCm39) |
|
probably null |
Het |
| Dnah7b |
T |
A |
1: 46,148,462 (GRCm39) |
D279E |
probably benign |
Het |
| Eif1ad10 |
T |
C |
12: 88,216,524 (GRCm39) |
N116S |
probably benign |
Het |
| Fam117a |
A |
G |
11: 95,269,660 (GRCm39) |
N308S |
probably benign |
Het |
| Fasn |
A |
G |
11: 120,704,245 (GRCm39) |
V1419A |
probably damaging |
Het |
| Fhad1 |
A |
G |
4: 141,678,802 (GRCm39) |
S625P |
probably benign |
Het |
| Gemin5 |
A |
G |
11: 58,038,754 (GRCm39) |
V585A |
probably benign |
Het |
| Gm5145 |
C |
A |
17: 20,790,646 (GRCm39) |
P8Q |
probably benign |
Het |
| Herc1 |
C |
A |
9: 66,323,629 (GRCm39) |
T1381K |
probably damaging |
Het |
| Herc6 |
T |
C |
6: 57,637,107 (GRCm39) |
I824T |
probably damaging |
Het |
| Klrb1 |
C |
T |
6: 128,687,050 (GRCm39) |
V161I |
probably benign |
Het |
| Krtap31-1 |
A |
G |
11: 99,799,258 (GRCm39) |
N154D |
not run |
Het |
| Lcp1 |
A |
T |
14: 75,437,871 (GRCm39) |
I94F |
probably benign |
Het |
| Lin7a |
A |
T |
10: 107,218,552 (GRCm39) |
Q154L |
possibly damaging |
Het |
| Lnx1 |
T |
C |
5: 74,846,351 (GRCm39) |
Y33C |
probably damaging |
Het |
| Myo5b |
T |
C |
18: 74,834,517 (GRCm39) |
V859A |
probably benign |
Het |
| Ncbp1 |
A |
G |
4: 46,170,015 (GRCm39) |
Q696R |
probably damaging |
Het |
| Neurl1b |
C |
G |
17: 26,657,720 (GRCm39) |
H219Q |
probably benign |
Het |
| Nme8 |
T |
C |
13: 19,842,999 (GRCm39) |
E392G |
probably benign |
Het |
| Nufip1 |
CAAAACAGAAAACAGAAAAC |
CAAAACAGAAAACAGAAAACAGAAAAC |
14: 76,349,414 (GRCm39) |
|
probably null |
Het |
| Nuggc |
A |
G |
14: 65,850,975 (GRCm39) |
I298V |
probably damaging |
Het |
| Nup155 |
A |
C |
15: 8,183,180 (GRCm39) |
K1247Q |
probably damaging |
Het |
| Or1a1 |
A |
G |
11: 74,087,033 (GRCm39) |
K235E |
probably damaging |
Het |
| Or5c1 |
A |
T |
2: 37,221,771 (GRCm39) |
E4V |
probably benign |
Het |
| Otud4 |
T |
A |
8: 80,382,493 (GRCm39) |
|
probably null |
Het |
| Pacc1 |
A |
G |
1: 191,073,065 (GRCm39) |
N162S |
probably benign |
Het |
| Pcdhb18 |
T |
C |
18: 37,624,749 (GRCm39) |
V693A |
probably damaging |
Het |
| Prkca |
A |
T |
11: 107,905,170 (GRCm39) |
N189K |
probably damaging |
Het |
| Rbm24 |
A |
G |
13: 46,582,683 (GRCm39) |
I201V |
probably benign |
Het |
| Reep6 |
T |
C |
10: 80,169,627 (GRCm39) |
L105P |
probably damaging |
Het |
| Retreg1 |
T |
C |
15: 25,941,126 (GRCm39) |
|
probably benign |
Het |
| Rev3l |
C |
T |
10: 39,712,718 (GRCm39) |
T2382I |
probably benign |
Het |
| Rnf31 |
A |
G |
14: 55,831,818 (GRCm39) |
N230S |
probably benign |
Het |
| Rreb1 |
T |
C |
13: 38,115,548 (GRCm39) |
L969P |
probably benign |
Het |
| Rsph4a |
T |
A |
10: 33,785,029 (GRCm39) |
N313K |
probably damaging |
Het |
| Serpina3f |
T |
A |
12: 104,183,525 (GRCm39) |
L129Q |
probably damaging |
Het |
| Slc9a2 |
T |
A |
1: 40,758,157 (GRCm39) |
V232D |
probably damaging |
Het |
| Stmn2 |
T |
C |
3: 8,619,925 (GRCm39) |
L121P |
probably damaging |
Het |
| Svep1 |
C |
T |
4: 58,097,424 (GRCm39) |
G1373D |
probably damaging |
Het |
| Tex55 |
C |
T |
16: 38,648,453 (GRCm39) |
D219N |
possibly damaging |
Het |
| Tns1 |
C |
A |
1: 73,991,636 (GRCm39) |
R1014L |
possibly damaging |
Het |
| Top2b |
T |
C |
14: 16,416,620 (GRCm38) |
S1127P |
possibly damaging |
Het |
| Txndc16 |
A |
T |
14: 45,373,324 (GRCm39) |
C768* |
probably null |
Het |
| Ubl7 |
A |
T |
9: 57,837,052 (GRCm39) |
E354D |
probably benign |
Het |
| Ush2a |
T |
C |
1: 188,516,905 (GRCm39) |
L3205P |
possibly damaging |
Het |
| Xirp2 |
A |
G |
2: 67,340,917 (GRCm39) |
T1053A |
possibly damaging |
Het |
| Zbtb21 |
A |
G |
16: 97,753,077 (GRCm39) |
L402P |
probably damaging |
Het |
| Zfp27 |
T |
A |
7: 29,594,221 (GRCm39) |
K581N |
possibly damaging |
Het |
| Zfp62 |
A |
T |
11: 49,105,903 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Pcnx3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01616:Pcnx3
|
APN |
19 |
5,717,287 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01667:Pcnx3
|
APN |
19 |
5,736,658 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL01704:Pcnx3
|
APN |
19 |
5,717,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01752:Pcnx3
|
APN |
19 |
5,715,365 (GRCm39) |
nonsense |
probably null |
|
|
IGL01791:Pcnx3
|
APN |
19 |
5,723,295 (GRCm39) |
missense |
probably benign |
0.39 |
|
IGL01937:Pcnx3
|
APN |
19 |
5,727,691 (GRCm39) |
missense |
probably benign |
|
|
IGL01987:Pcnx3
|
APN |
19 |
5,727,507 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02073:Pcnx3
|
APN |
19 |
5,729,414 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02417:Pcnx3
|
APN |
19 |
5,736,509 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL03143:Pcnx3
|
APN |
19 |
5,735,423 (GRCm39) |
missense |
probably damaging |
1.00 |
|
buns
|
UTSW |
19 |
5,733,368 (GRCm39) |
start codon destroyed |
probably null |
|
|
Pastries
|
UTSW |
19 |
5,733,367 (GRCm39) |
nonsense |
probably null |
|
|
pie
|
UTSW |
19 |
5,717,186 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7096_pcnx3_526
|
UTSW |
19 |
5,722,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
swirls
|
UTSW |
19 |
5,722,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
tip
|
UTSW |
19 |
5,733,808 (GRCm39) |
splice site |
probably benign |
|
|
PIT4453001:Pcnx3
|
UTSW |
19 |
5,722,784 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0234:Pcnx3
|
UTSW |
19 |
5,722,646 (GRCm39) |
missense |
probably benign |
0.12 |
|
R0234:Pcnx3
|
UTSW |
19 |
5,722,646 (GRCm39) |
missense |
probably benign |
0.12 |
|
R0360:Pcnx3
|
UTSW |
19 |
5,715,611 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0687:Pcnx3
|
UTSW |
19 |
5,734,361 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0718:Pcnx3
|
UTSW |
19 |
5,727,756 (GRCm39) |
splice site |
probably benign |
|
|
R0840:Pcnx3
|
UTSW |
19 |
5,735,729 (GRCm39) |
splice site |
probably null |
|
|
R0907:Pcnx3
|
UTSW |
19 |
5,721,553 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1251:Pcnx3
|
UTSW |
19 |
5,727,210 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1373:Pcnx3
|
UTSW |
19 |
5,715,544 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1467:Pcnx3
|
UTSW |
19 |
5,724,922 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R1467:Pcnx3
|
UTSW |
19 |
5,724,922 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R1572:Pcnx3
|
UTSW |
19 |
5,735,375 (GRCm39) |
nonsense |
probably null |
|
|
R1602:Pcnx3
|
UTSW |
19 |
5,722,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1628:Pcnx3
|
UTSW |
19 |
5,736,093 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1635:Pcnx3
|
UTSW |
19 |
5,715,773 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1670:Pcnx3
|
UTSW |
19 |
5,723,343 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1889:Pcnx3
|
UTSW |
19 |
5,722,684 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1898:Pcnx3
|
UTSW |
19 |
5,722,615 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2113:Pcnx3
|
UTSW |
19 |
5,721,584 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2147:Pcnx3
|
UTSW |
19 |
5,717,633 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2358:Pcnx3
|
UTSW |
19 |
5,733,368 (GRCm39) |
start codon destroyed |
probably null |
|
|
R2358:Pcnx3
|
UTSW |
19 |
5,733,367 (GRCm39) |
nonsense |
probably null |
|
|
R2871:Pcnx3
|
UTSW |
19 |
5,733,774 (GRCm39) |
intron |
probably benign |
|
|
R3699:Pcnx3
|
UTSW |
19 |
5,722,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3712:Pcnx3
|
UTSW |
19 |
5,733,368 (GRCm39) |
start codon destroyed |
probably null |
|
|
R3712:Pcnx3
|
UTSW |
19 |
5,733,367 (GRCm39) |
nonsense |
probably null |
|
|
R3798:Pcnx3
|
UTSW |
19 |
5,728,696 (GRCm39) |
nonsense |
probably null |
|
|
R3856:Pcnx3
|
UTSW |
19 |
5,728,995 (GRCm39) |
missense |
probably benign |
0.02 |
|
R3953:Pcnx3
|
UTSW |
19 |
5,733,808 (GRCm39) |
splice site |
probably benign |
|
|
R4613:Pcnx3
|
UTSW |
19 |
5,717,247 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R4781:Pcnx3
|
UTSW |
19 |
5,737,158 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4816:Pcnx3
|
UTSW |
19 |
5,738,023 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5338:Pcnx3
|
UTSW |
19 |
5,722,624 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5770:Pcnx3
|
UTSW |
19 |
5,731,607 (GRCm39) |
intron |
probably benign |
|
|
R5950:Pcnx3
|
UTSW |
19 |
5,717,186 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5951:Pcnx3
|
UTSW |
19 |
5,721,708 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R5969:Pcnx3
|
UTSW |
19 |
5,735,563 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6543:Pcnx3
|
UTSW |
19 |
5,715,275 (GRCm39) |
missense |
probably benign |
0.07 |
|
R6704:Pcnx3
|
UTSW |
19 |
5,736,515 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R7096:Pcnx3
|
UTSW |
19 |
5,722,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7177:Pcnx3
|
UTSW |
19 |
5,737,527 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7308:Pcnx3
|
UTSW |
19 |
5,736,175 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R7387:Pcnx3
|
UTSW |
19 |
5,723,364 (GRCm39) |
missense |
probably benign |
0.33 |
|
R7488:Pcnx3
|
UTSW |
19 |
5,717,487 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R7831:Pcnx3
|
UTSW |
19 |
5,735,989 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7850:Pcnx3
|
UTSW |
19 |
5,728,960 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R8120:Pcnx3
|
UTSW |
19 |
5,717,574 (GRCm39) |
missense |
probably benign |
|
|
R8139:Pcnx3
|
UTSW |
19 |
5,715,773 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8258:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8259:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8260:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8261:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8262:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8350:Pcnx3
|
UTSW |
19 |
5,723,254 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8411:Pcnx3
|
UTSW |
19 |
5,729,618 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8429:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8431:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8443:Pcnx3
|
UTSW |
19 |
5,736,670 (GRCm39) |
missense |
probably benign |
|
|
R8450:Pcnx3
|
UTSW |
19 |
5,723,254 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8494:Pcnx3
|
UTSW |
19 |
5,725,404 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8790:Pcnx3
|
UTSW |
19 |
5,735,206 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R8939:Pcnx3
|
UTSW |
19 |
5,730,347 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9065:Pcnx3
|
UTSW |
19 |
5,717,582 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R9070:Pcnx3
|
UTSW |
19 |
5,715,601 (GRCm39) |
missense |
probably benign |
0.33 |
|
X0028:Pcnx3
|
UTSW |
19 |
5,734,455 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0053:Pcnx3
|
UTSW |
19 |
5,736,650 (GRCm39) |
splice site |
probably null |
|
|
Z1176:Pcnx3
|
UTSW |
19 |
5,737,248 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
Z1177:Pcnx3
|
UTSW |
19 |
5,721,654 (GRCm39) |
missense |
probably benign |
0.17 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTGGAGTCCAGCAGAGACTG -3'
(R):5'- TGCACCTCTTGGTATGGATG -3'
Sequencing Primer
(F):5'- GAATGGGCATGGGGGCTG -3'
(R):5'- TGCTGCACTTGAGAGCC -3'
|
| Posted On |
2019-11-12 |
Incidental Mutation