Incidental Mutation 'R7672:Ptprj'
| ID |
592204 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ptprj
|
| Ensembl Gene |
ENSMUSG00000025314 |
| Gene Name |
protein tyrosine phosphatase receptor type J |
| Synonyms |
Byp, RPTPJ, Scc1, CD148, DEP-1, Scc-1 |
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.251)
|
| Stock # |
R7672 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
90260098-90410939 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 90290940 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Aspartic acid
at position 600
(N600D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000129592
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000111493]
[ENSMUST00000111495]
[ENSMUST00000168621]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000111493
AA Change: N414D
PolyPhen 2
Score 0.795 (Sensitivity: 0.85; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000107119
Gene: ENSMUSG00000025314
AA Change: N414D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
34 |
46 |
N/A |
INTRINSIC |
|
FN3
|
47 |
182 |
3.76e-6 |
SMART |
|
FN3
|
194 |
271 |
4.56e-5 |
SMART |
|
FN3
|
282 |
357 |
5.32e-6 |
SMART |
|
FN3
|
368 |
446 |
2.19e-7 |
SMART |
|
FN3
|
455 |
531 |
5e-2 |
SMART |
|
FN3
|
546 |
628 |
2.77e1 |
SMART |
|
low complexity region
|
637 |
650 |
N/A |
INTRINSIC |
|
Blast:PTPc
|
714 |
797 |
8e-26 |
BLAST |
|
PTPc
|
867 |
1127 |
3.37e-133 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000111495
AA Change: N507D
PolyPhen 2
Score 0.638 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000107121
Gene: ENSMUSG00000025314
AA Change: N507D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
14 |
25 |
N/A |
INTRINSIC |
|
FN3
|
59 |
131 |
2.85e-6 |
SMART |
|
FN3
|
140 |
275 |
3.76e-6 |
SMART |
|
FN3
|
287 |
364 |
4.56e-5 |
SMART |
|
FN3
|
375 |
450 |
5.32e-6 |
SMART |
|
FN3
|
461 |
539 |
2.19e-7 |
SMART |
|
FN3
|
548 |
624 |
5e-2 |
SMART |
|
FN3
|
639 |
721 |
2.77e1 |
SMART |
|
low complexity region
|
730 |
743 |
N/A |
INTRINSIC |
|
Blast:PTPc
|
807 |
890 |
1e-25 |
BLAST |
|
PTPc
|
960 |
1220 |
3.37e-133 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000168621
AA Change: N600D
PolyPhen 2
Score 0.485 (Sensitivity: 0.88; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000129592
Gene: ENSMUSG00000025314
AA Change: N600D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
16 |
N/A |
INTRINSIC |
|
low complexity region
|
26 |
94 |
N/A |
INTRINSIC |
|
low complexity region
|
133 |
140 |
N/A |
INTRINSIC |
|
FN3
|
152 |
224 |
2.85e-6 |
SMART |
|
FN3
|
233 |
368 |
3.76e-6 |
SMART |
|
FN3
|
380 |
457 |
4.56e-5 |
SMART |
|
FN3
|
468 |
543 |
5.32e-6 |
SMART |
|
FN3
|
554 |
632 |
2.19e-7 |
SMART |
|
FN3
|
641 |
717 |
5e-2 |
SMART |
|
FN3
|
732 |
814 |
2.77e1 |
SMART |
|
low complexity region
|
823 |
836 |
N/A |
INTRINSIC |
|
Blast:PTPc
|
900 |
983 |
1e-25 |
BLAST |
|
PTPc
|
1053 |
1313 |
3.37e-133 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a null allele die in utero displaying severe growth retardation and cardiovascular defects. Homozygotes for a second null allele are viable, fertile and healthy with no spontaneous tumor formation. Homozygotes for a third null allele show sterility and a block B cell development. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 78 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 9130023H24Rik |
T |
C |
7: 127,836,191 (GRCm39) |
H134R |
probably damaging |
Het |
| Adcy4 |
A |
G |
14: 56,018,362 (GRCm39) |
M195T |
probably benign |
Het |
| Aktip |
T |
C |
8: 91,856,285 (GRCm39) |
N64S |
possibly damaging |
Het |
| Aldoart1 |
C |
A |
4: 72,770,747 (GRCm39) |
M20I |
probably benign |
Het |
| Alms1 |
T |
C |
6: 85,592,333 (GRCm39) |
L395P |
probably damaging |
Het |
| Ankrd9 |
C |
A |
12: 110,943,180 (GRCm39) |
V252F |
probably benign |
Het |
| Apof |
A |
T |
10: 128,104,885 (GRCm39) |
H13L |
probably benign |
Het |
| Bahcc1 |
T |
C |
11: 120,174,172 (GRCm39) |
F1644S |
possibly damaging |
Het |
| Baz2a |
A |
G |
10: 127,959,726 (GRCm39) |
D1377G |
possibly damaging |
Het |
| Bbox1 |
T |
A |
2: 110,135,794 (GRCm39) |
I62F |
probably damaging |
Het |
| BC028528 |
CTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTT |
CTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTT |
3: 95,795,448 (GRCm39) |
|
probably benign |
Het |
| BC028528 |
TCTGTGGTCACTGGT |
TCTGTGGTCACTGGTGCTGTGGTCACTGGT |
3: 95,795,487 (GRCm39) |
|
probably benign |
Het |
| BC028528 |
GTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTG |
GTTCTGTGGTCACTGATTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTG |
3: 95,795,455 (GRCm39) |
|
probably benign |
Het |
| Bcas3 |
C |
T |
11: 85,286,213 (GRCm39) |
R124* |
probably null |
Het |
| Bpnt1 |
T |
C |
1: 185,078,879 (GRCm39) |
V114A |
probably damaging |
Het |
| Ccnd1 |
C |
T |
7: 144,487,793 (GRCm39) |
R228H |
possibly damaging |
Het |
| Cd244a |
T |
C |
1: 171,404,853 (GRCm39) |
V235A |
probably benign |
Het |
| Cramp1 |
C |
T |
17: 25,201,440 (GRCm39) |
E681K |
probably damaging |
Het |
| Crebbp |
C |
T |
16: 3,902,574 (GRCm39) |
A2222T |
probably benign |
Het |
| Cyp1a2 |
T |
A |
9: 57,589,620 (GRCm39) |
T65S |
probably benign |
Het |
| Cyp26b1 |
T |
G |
6: 84,561,351 (GRCm39) |
K104Q |
probably benign |
Het |
| D430041D05Rik |
T |
C |
2: 104,071,581 (GRCm39) |
I556V |
probably benign |
Het |
| Dnase1l2 |
A |
G |
17: 24,661,219 (GRCm39) |
L102P |
probably damaging |
Het |
| Eef1ece2 |
C |
A |
16: 20,457,417 (GRCm39) |
A483E |
probably damaging |
Het |
| Elac1 |
C |
T |
18: 73,871,925 (GRCm39) |
G357S |
probably benign |
Het |
| Enam |
C |
A |
5: 88,651,830 (GRCm39) |
T1113N |
possibly damaging |
Het |
| Eogt |
A |
T |
6: 97,090,870 (GRCm39) |
I423N |
probably damaging |
Het |
| Epc2 |
T |
C |
2: 49,435,831 (GRCm39) |
S612P |
possibly damaging |
Het |
| Fam107b |
T |
C |
2: 3,773,959 (GRCm39) |
V24A |
probably damaging |
Het |
| Fhip2a |
A |
G |
19: 57,373,750 (GRCm39) |
H670R |
possibly damaging |
Het |
| Foxj3 |
C |
T |
4: 119,477,429 (GRCm39) |
P413L |
unknown |
Het |
| Frg1 |
T |
C |
8: 41,870,040 (GRCm39) |
|
probably benign |
Het |
| Fsip2 |
T |
A |
2: 82,820,455 (GRCm39) |
V5396D |
possibly damaging |
Het |
| Hdlbp |
T |
C |
1: 93,364,821 (GRCm39) |
T149A |
possibly damaging |
Het |
| Heatr1 |
A |
T |
13: 12,453,545 (GRCm39) |
Q2140L |
probably damaging |
Het |
| Iqcd |
T |
C |
5: 120,744,881 (GRCm39) |
L403P |
probably damaging |
Het |
| Kifbp |
A |
G |
10: 62,413,852 (GRCm39) |
I102T |
probably benign |
Het |
| Kpna2 |
T |
G |
11: 106,879,789 (GRCm39) |
N505T |
probably benign |
Het |
| Lipo3 |
T |
A |
19: 33,757,785 (GRCm39) |
E228V |
probably benign |
Het |
| Map4k3 |
C |
T |
17: 80,922,500 (GRCm39) |
V474I |
possibly damaging |
Het |
| Mrpl11 |
T |
C |
19: 5,012,424 (GRCm39) |
S2P |
probably damaging |
Het |
| Mug2 |
A |
G |
6: 122,017,678 (GRCm39) |
I472V |
probably benign |
Het |
| Myom1 |
G |
A |
17: 71,391,235 (GRCm39) |
V915M |
possibly damaging |
Het |
| Nedd9 |
A |
T |
13: 41,492,198 (GRCm39) |
I104N |
possibly damaging |
Het |
| Nphp3 |
A |
G |
9: 103,909,159 (GRCm39) |
M790V |
probably benign |
Het |
| Nr3c2 |
C |
T |
8: 77,635,838 (GRCm39) |
P313L |
probably damaging |
Het |
| Obsl1 |
A |
G |
1: 75,469,365 (GRCm39) |
V1192A |
probably benign |
Het |
| Or10j2 |
C |
T |
1: 173,098,440 (GRCm39) |
R233W |
probably benign |
Het |
| Or52e7 |
A |
G |
7: 104,684,750 (GRCm39) |
H115R |
probably damaging |
Het |
| Or5t16 |
T |
C |
2: 86,818,663 (GRCm39) |
I286V |
possibly damaging |
Het |
| Prr5l |
T |
G |
2: 101,565,083 (GRCm39) |
E151A |
probably damaging |
Het |
| Psmb8 |
G |
T |
17: 34,417,404 (GRCm39) |
R11L |
probably benign |
Het |
| Ptprg |
T |
A |
14: 12,211,668 (GRCm38) |
H983Q |
probably benign |
Het |
| Rasgrp1 |
T |
C |
2: 117,118,424 (GRCm39) |
I522V |
probably damaging |
Het |
| Rc3h1 |
A |
G |
1: 160,778,454 (GRCm39) |
S460G |
probably damaging |
Het |
| Rhot2 |
A |
G |
17: 26,062,079 (GRCm39) |
|
probably null |
Het |
| Sall1 |
T |
C |
8: 89,757,927 (GRCm39) |
T726A |
probably damaging |
Het |
| Samd9l |
G |
A |
6: 3,373,646 (GRCm39) |
T1205I |
probably benign |
Het |
| Sh2b3 |
C |
T |
5: 121,956,822 (GRCm39) |
|
probably null |
Het |
| Slc22a18 |
G |
T |
7: 143,044,557 (GRCm39) |
C170F |
probably damaging |
Het |
| Slc24a1 |
G |
A |
9: 64,855,209 (GRCm39) |
T566I |
unknown |
Het |
| Slc4a5 |
T |
A |
6: 83,237,517 (GRCm39) |
C167S |
probably damaging |
Het |
| Slc8b1 |
T |
G |
5: 120,671,100 (GRCm39) |
V579G |
probably damaging |
Het |
| Snrnp200 |
T |
C |
2: 127,063,822 (GRCm39) |
V667A |
probably damaging |
Het |
| Sp8 |
C |
A |
12: 118,813,070 (GRCm39) |
S308R |
possibly damaging |
Het |
| Srsf9 |
T |
A |
5: 115,468,619 (GRCm39) |
V85E |
probably damaging |
Het |
| Syne1 |
T |
C |
10: 5,168,527 (GRCm39) |
I5285V |
probably benign |
Het |
| Tmem245 |
T |
C |
4: 56,947,069 (GRCm39) |
I115V |
probably benign |
Het |
| Triqk |
A |
G |
4: 12,980,502 (GRCm39) |
D82G |
probably benign |
Het |
| Trmt11 |
A |
T |
10: 30,463,520 (GRCm39) |
S198R |
probably damaging |
Het |
| Ube4b |
C |
T |
4: 149,471,661 (GRCm39) |
R75Q |
probably benign |
Het |
| Ugt3a1 |
C |
T |
15: 9,310,779 (GRCm39) |
Q354* |
probably null |
Het |
| Vmn1r202 |
A |
G |
13: 22,685,850 (GRCm39) |
V189A |
probably benign |
Het |
| Vmn2r26 |
A |
G |
6: 124,016,606 (GRCm39) |
I357V |
probably benign |
Het |
| Wdr6 |
T |
C |
9: 108,450,947 (GRCm39) |
K914R |
probably benign |
Het |
| Zfat |
T |
C |
15: 68,130,535 (GRCm39) |
M1V |
probably null |
Het |
| Zfp207 |
A |
G |
11: 80,280,116 (GRCm39) |
M171V |
probably benign |
Het |
| Zfp568 |
C |
T |
7: 29,697,212 (GRCm39) |
T44I |
probably damaging |
Het |
|
| Other mutations in Ptprj |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01528:Ptprj
|
APN |
2 |
90,282,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01594:Ptprj
|
APN |
2 |
90,271,139 (GRCm39) |
splice site |
probably benign |
|
|
IGL01767:Ptprj
|
APN |
2 |
90,299,918 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL01917:Ptprj
|
APN |
2 |
90,300,093 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01981:Ptprj
|
APN |
2 |
90,270,256 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02830:Ptprj
|
APN |
2 |
90,283,488 (GRCm39) |
missense |
probably benign |
0.22 |
|
IGL02955:Ptprj
|
APN |
2 |
90,298,808 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL03102:Ptprj
|
APN |
2 |
90,309,312 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL03150:Ptprj
|
APN |
2 |
90,290,955 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL03210:Ptprj
|
APN |
2 |
90,300,070 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02799:Ptprj
|
UTSW |
2 |
90,299,942 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0083:Ptprj
|
UTSW |
2 |
90,300,121 (GRCm39) |
splice site |
probably null |
|
|
R0108:Ptprj
|
UTSW |
2 |
90,300,121 (GRCm39) |
splice site |
probably null |
|
|
R0579:Ptprj
|
UTSW |
2 |
90,266,913 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R1130:Ptprj
|
UTSW |
2 |
90,283,765 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1160:Ptprj
|
UTSW |
2 |
90,274,868 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1238:Ptprj
|
UTSW |
2 |
90,274,758 (GRCm39) |
splice site |
probably null |
|
|
R1507:Ptprj
|
UTSW |
2 |
90,301,631 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R1552:Ptprj
|
UTSW |
2 |
90,301,497 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1607:Ptprj
|
UTSW |
2 |
90,293,664 (GRCm39) |
missense |
probably benign |
0.14 |
|
R1693:Ptprj
|
UTSW |
2 |
90,280,141 (GRCm39) |
nonsense |
probably null |
|
|
R2016:Ptprj
|
UTSW |
2 |
90,294,958 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2017:Ptprj
|
UTSW |
2 |
90,294,958 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2044:Ptprj
|
UTSW |
2 |
90,293,439 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R2322:Ptprj
|
UTSW |
2 |
90,301,473 (GRCm39) |
missense |
probably benign |
0.06 |
|
R2516:Ptprj
|
UTSW |
2 |
90,305,340 (GRCm39) |
splice site |
probably benign |
|
|
R3106:Ptprj
|
UTSW |
2 |
90,270,975 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3964:Ptprj
|
UTSW |
2 |
90,298,785 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4201:Ptprj
|
UTSW |
2 |
90,293,439 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4533:Ptprj
|
UTSW |
2 |
90,270,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4680:Ptprj
|
UTSW |
2 |
90,290,840 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4738:Ptprj
|
UTSW |
2 |
90,270,987 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4983:Ptprj
|
UTSW |
2 |
90,290,876 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5137:Ptprj
|
UTSW |
2 |
90,299,992 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R5349:Ptprj
|
UTSW |
2 |
90,301,605 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5369:Ptprj
|
UTSW |
2 |
90,299,985 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5718:Ptprj
|
UTSW |
2 |
90,288,613 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5914:Ptprj
|
UTSW |
2 |
90,283,684 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R6022:Ptprj
|
UTSW |
2 |
90,301,667 (GRCm39) |
missense |
probably benign |
0.14 |
|
R6341:Ptprj
|
UTSW |
2 |
90,288,693 (GRCm39) |
missense |
probably benign |
|
|
R6421:Ptprj
|
UTSW |
2 |
90,301,484 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R6724:Ptprj
|
UTSW |
2 |
90,281,195 (GRCm39) |
missense |
probably benign |
0.04 |
|
R6831:Ptprj
|
UTSW |
2 |
90,290,991 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6939:Ptprj
|
UTSW |
2 |
90,289,858 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6972:Ptprj
|
UTSW |
2 |
90,410,747 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R7134:Ptprj
|
UTSW |
2 |
90,294,822 (GRCm39) |
missense |
probably benign |
0.16 |
|
R7149:Ptprj
|
UTSW |
2 |
90,274,790 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7243:Ptprj
|
UTSW |
2 |
90,276,765 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7335:Ptprj
|
UTSW |
2 |
90,271,126 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7439:Ptprj
|
UTSW |
2 |
90,280,163 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R7441:Ptprj
|
UTSW |
2 |
90,280,163 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R7498:Ptprj
|
UTSW |
2 |
90,266,909 (GRCm39) |
nonsense |
probably null |
|
|
R7571:Ptprj
|
UTSW |
2 |
90,285,530 (GRCm39) |
missense |
probably benign |
0.24 |
|
R7657:Ptprj
|
UTSW |
2 |
90,282,501 (GRCm39) |
splice site |
probably null |
|
|
R7849:Ptprj
|
UTSW |
2 |
90,274,804 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7939:Ptprj
|
UTSW |
2 |
90,295,009 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7958:Ptprj
|
UTSW |
2 |
90,299,971 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R8338:Ptprj
|
UTSW |
2 |
90,301,481 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R8354:Ptprj
|
UTSW |
2 |
90,300,061 (GRCm39) |
missense |
probably benign |
0.43 |
|
R8556:Ptprj
|
UTSW |
2 |
90,271,044 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8695:Ptprj
|
UTSW |
2 |
90,301,481 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R8784:Ptprj
|
UTSW |
2 |
90,290,856 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R8984:Ptprj
|
UTSW |
2 |
90,270,987 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9054:Ptprj
|
UTSW |
2 |
90,290,984 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9056:Ptprj
|
UTSW |
2 |
90,288,613 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9147:Ptprj
|
UTSW |
2 |
90,288,562 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9148:Ptprj
|
UTSW |
2 |
90,288,562 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9168:Ptprj
|
UTSW |
2 |
90,294,916 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R9314:Ptprj
|
UTSW |
2 |
90,301,631 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R9337:Ptprj
|
UTSW |
2 |
90,270,238 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9546:Ptprj
|
UTSW |
2 |
90,274,805 (GRCm39) |
missense |
probably benign |
0.08 |
|
RF013:Ptprj
|
UTSW |
2 |
90,301,514 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Ptprj
|
UTSW |
2 |
90,290,913 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCTGTAACCCAGAGGCATAGCC -3'
(R):5'- CTTTGAAGTGAAGCTGGAATCATG -3'
Sequencing Primer
(F):5'- AGTTACTGTACTTCCTCCATGGG -3'
(R):5'- GCACCACTGAAATGCAGT -3'
|
| Posted On |
2019-11-12 |
Incidental Mutation