Incidental Mutation 'R7698:Rusc2'
| ID |
593766 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Rusc2
|
| Ensembl Gene |
ENSMUSG00000035969 |
| Gene Name |
RUN and SH3 domain containing 2 |
| Synonyms |
|
| MMRRC Submission |
045759-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.207)
|
| Stock # |
R7698 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
4 |
| Chromosomal Location |
43381979-43427088 bp(+) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
C to T
at 43414900 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamine to Stop codon
at position 69
(Q69*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000038379
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000035645]
[ENSMUST00000098106]
[ENSMUST00000125399]
[ENSMUST00000131668]
[ENSMUST00000135216]
[ENSMUST00000136360]
[ENSMUST00000139198]
[ENSMUST00000144911]
[ENSMUST00000149221]
[ENSMUST00000152322]
[ENSMUST00000173682]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably null
Transcript: ENSMUST00000035645
AA Change: Q69*
|
| SMART Domains |
Protein: ENSMUSP00000038379
Gene: ENSMUSG00000035969
AA Change: Q69*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
39 |
47 |
N/A |
INTRINSIC |
|
low complexity region
|
212 |
230 |
N/A |
INTRINSIC |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
low complexity region
|
411 |
427 |
N/A |
INTRINSIC |
|
low complexity region
|
435 |
448 |
N/A |
INTRINSIC |
|
low complexity region
|
530 |
544 |
N/A |
INTRINSIC |
|
low complexity region
|
600 |
617 |
N/A |
INTRINSIC |
|
low complexity region
|
795 |
809 |
N/A |
INTRINSIC |
|
RUN
|
1109 |
1177 |
3.66e-21 |
SMART |
|
low complexity region
|
1235 |
1260 |
N/A |
INTRINSIC |
|
low complexity region
|
1289 |
1324 |
N/A |
INTRINSIC |
|
low complexity region
|
1330 |
1341 |
N/A |
INTRINSIC |
|
SH3
|
1457 |
1512 |
7.4e-11 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000098106
AA Change: Q69*
|
| SMART Domains |
Protein: ENSMUSP00000095710
Gene: ENSMUSG00000035969
AA Change: Q69*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
39 |
47 |
N/A |
INTRINSIC |
|
low complexity region
|
212 |
230 |
N/A |
INTRINSIC |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
low complexity region
|
411 |
427 |
N/A |
INTRINSIC |
|
low complexity region
|
435 |
448 |
N/A |
INTRINSIC |
|
low complexity region
|
530 |
544 |
N/A |
INTRINSIC |
|
low complexity region
|
600 |
617 |
N/A |
INTRINSIC |
|
low complexity region
|
795 |
809 |
N/A |
INTRINSIC |
|
RUN
|
1109 |
1177 |
3.66e-21 |
SMART |
|
low complexity region
|
1235 |
1260 |
N/A |
INTRINSIC |
|
low complexity region
|
1289 |
1324 |
N/A |
INTRINSIC |
|
low complexity region
|
1330 |
1341 |
N/A |
INTRINSIC |
|
SH3
|
1457 |
1512 |
7.4e-11 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000125399
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000131668
AA Change: Q69*
|
| SMART Domains |
Protein: ENSMUSP00000118528
Gene: ENSMUSG00000035969
AA Change: Q69*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
39 |
47 |
N/A |
INTRINSIC |
|
low complexity region
|
212 |
230 |
N/A |
INTRINSIC |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
low complexity region
|
411 |
427 |
N/A |
INTRINSIC |
|
low complexity region
|
435 |
448 |
N/A |
INTRINSIC |
|
low complexity region
|
530 |
544 |
N/A |
INTRINSIC |
|
low complexity region
|
600 |
617 |
N/A |
INTRINSIC |
|
low complexity region
|
795 |
809 |
N/A |
INTRINSIC |
|
RUN
|
1109 |
1177 |
3.66e-21 |
SMART |
|
low complexity region
|
1235 |
1260 |
N/A |
INTRINSIC |
|
low complexity region
|
1289 |
1324 |
N/A |
INTRINSIC |
|
low complexity region
|
1330 |
1341 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000135216
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000136360
|
| SMART Domains |
Protein: ENSMUSP00000123431
Gene: ENSMUSG00000035969
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
39 |
47 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000139198
AA Change: Q69*
|
| SMART Domains |
Protein: ENSMUSP00000121528
Gene: ENSMUSG00000035969
AA Change: Q69*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
39 |
47 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000144911
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000149221
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000152322
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000173682
AA Change: Q69*
|
| SMART Domains |
Protein: ENSMUSP00000133715
Gene: ENSMUSG00000035969
AA Change: Q69*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
39 |
47 |
N/A |
INTRINSIC |
|
low complexity region
|
212 |
230 |
N/A |
INTRINSIC |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
low complexity region
|
411 |
427 |
N/A |
INTRINSIC |
|
low complexity region
|
435 |
448 |
N/A |
INTRINSIC |
|
low complexity region
|
530 |
544 |
N/A |
INTRINSIC |
|
low complexity region
|
685 |
703 |
N/A |
INTRINSIC |
|
low complexity region
|
733 |
740 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.2%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a RUN and SH3 domain containing protein that interacts with Rab1b and Rab1-binding protein GM130. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jun 2012]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 73 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A630023A22Rik |
C |
A |
14: 33,774,570 (GRCm39) |
L140F |
unknown |
Het |
| Actn1 |
T |
C |
12: 80,221,311 (GRCm39) |
T581A |
probably benign |
Het |
| Ak9 |
T |
C |
10: 41,224,072 (GRCm39) |
L495S |
|
Het |
| Aldh5a1 |
T |
C |
13: 25,095,731 (GRCm39) |
D462G |
probably damaging |
Het |
| Amz2 |
A |
G |
11: 109,319,833 (GRCm39) |
D73G |
probably damaging |
Het |
| Ank2 |
A |
G |
3: 126,825,860 (GRCm39) |
Y361H |
probably benign |
Het |
| Atp8b1 |
A |
G |
18: 64,704,093 (GRCm39) |
Y342H |
probably benign |
Het |
| Atp8b5 |
C |
T |
4: 43,366,735 (GRCm39) |
T833I |
probably benign |
Het |
| Camkk2 |
A |
G |
5: 122,884,482 (GRCm39) |
I313T |
probably damaging |
Het |
| Cdk18 |
T |
C |
1: 132,050,116 (GRCm39) |
T20A |
probably damaging |
Het |
| Cenpf |
A |
T |
1: 189,394,269 (GRCm39) |
C479S |
probably benign |
Het |
| Cfap221 |
C |
A |
1: 119,889,659 (GRCm39) |
E192* |
probably null |
Het |
| Cfap44 |
C |
T |
16: 44,254,149 (GRCm39) |
H958Y |
probably damaging |
Het |
| Cic |
A |
T |
7: 24,972,597 (GRCm39) |
Q776L |
possibly damaging |
Het |
| Cldn17 |
C |
A |
16: 88,303,244 (GRCm39) |
G162* |
probably null |
Het |
| Col19a1 |
T |
A |
1: 24,351,159 (GRCm39) |
Y748F |
probably benign |
Het |
| Col27a1 |
C |
T |
4: 63,143,955 (GRCm39) |
P548S |
possibly damaging |
Het |
| Cracdl |
T |
G |
1: 37,664,452 (GRCm39) |
E482A |
probably benign |
Het |
| Ctsr |
T |
A |
13: 61,310,381 (GRCm39) |
M92L |
probably benign |
Het |
| Cyp2d12 |
T |
C |
15: 82,443,171 (GRCm39) |
V360A |
probably benign |
Het |
| Defa34 |
G |
T |
8: 22,156,645 (GRCm39) |
C91F |
probably damaging |
Het |
| Dennd2c |
G |
A |
3: 103,072,359 (GRCm39) |
V815I |
possibly damaging |
Het |
| Dlgap4 |
C |
T |
2: 156,591,015 (GRCm39) |
Q734* |
probably null |
Het |
| Dph1 |
A |
T |
11: 75,081,267 (GRCm39) |
S7T |
probably benign |
Het |
| Dpp8 |
T |
C |
9: 64,949,618 (GRCm39) |
V121A |
probably benign |
Het |
| Dst |
G |
A |
1: 34,229,468 (GRCm39) |
G2354S |
probably benign |
Het |
| Duox2 |
A |
T |
2: 122,111,245 (GRCm39) |
L1453Q |
probably damaging |
Het |
| Ecpas |
C |
G |
4: 58,832,660 (GRCm39) |
C900S |
unknown |
Het |
| Exosc10 |
T |
A |
4: 148,642,955 (GRCm39) |
S11T |
probably benign |
Het |
| Fetub |
A |
G |
16: 22,758,059 (GRCm39) |
T281A |
probably benign |
Het |
| Flii |
A |
T |
11: 60,610,918 (GRCm39) |
W504R |
probably damaging |
Het |
| Gm5093 |
T |
C |
17: 46,750,866 (GRCm39) |
R54G |
possibly damaging |
Het |
| Gmcl1 |
T |
C |
6: 86,684,397 (GRCm39) |
D375G |
probably benign |
Het |
| Hikeshi |
A |
T |
7: 89,572,889 (GRCm39) |
N101K |
probably benign |
Het |
| Hmcn2 |
T |
C |
2: 31,313,165 (GRCm39) |
V3458A |
probably damaging |
Het |
| Hspa2 |
A |
G |
12: 76,452,083 (GRCm39) |
N259S |
possibly damaging |
Het |
| Irf6 |
T |
C |
1: 192,844,075 (GRCm39) |
I110T |
probably damaging |
Het |
| Kcnj8 |
T |
A |
6: 142,511,479 (GRCm39) |
H376L |
probably damaging |
Het |
| Kdm6b |
G |
A |
11: 69,296,807 (GRCm39) |
P487S |
probably benign |
Het |
| Lcp1 |
C |
A |
14: 75,443,651 (GRCm39) |
Y222* |
probably null |
Het |
| Manea |
T |
C |
4: 26,327,763 (GRCm39) |
D426G |
probably damaging |
Het |
| Map3k20 |
G |
T |
2: 72,195,025 (GRCm39) |
E101* |
probably null |
Het |
| Map3k20 |
C |
G |
2: 72,268,658 (GRCm39) |
S555C |
probably benign |
Het |
| Mtmr7 |
G |
A |
8: 41,059,927 (GRCm39) |
A62V |
possibly damaging |
Het |
| Myo6 |
C |
T |
9: 80,124,938 (GRCm39) |
P6S |
unknown |
Het |
| Myoc |
A |
T |
1: 162,467,014 (GRCm39) |
Q61L |
probably damaging |
Het |
| N4bp2 |
T |
A |
5: 65,965,500 (GRCm39) |
M1183K |
probably benign |
Het |
| Or52e7 |
T |
A |
7: 104,685,114 (GRCm39) |
H236Q |
probably benign |
Het |
| Or5b114-ps1 |
T |
C |
19: 13,352,404 (GRCm39) |
F26S |
probably damaging |
Het |
| Or5b21 |
T |
C |
19: 12,840,077 (GRCm39) |
S313P |
possibly damaging |
Het |
| Or8b40 |
T |
A |
9: 38,027,188 (GRCm39) |
L37* |
probably null |
Het |
| Osbpl11 |
C |
G |
16: 33,054,817 (GRCm39) |
N633K |
probably benign |
Het |
| Pate7 |
T |
C |
9: 35,688,472 (GRCm39) |
M38V |
probably benign |
Het |
| Pcdhgb5 |
A |
G |
18: 37,865,684 (GRCm39) |
E493G |
probably damaging |
Het |
| Phf20 |
T |
A |
2: 156,136,058 (GRCm39) |
W626R |
probably damaging |
Het |
| Pkp2 |
C |
A |
16: 16,058,523 (GRCm39) |
Q402K |
probably benign |
Het |
| Plch2 |
C |
T |
4: 155,087,244 (GRCm39) |
D336N |
possibly damaging |
Het |
| Plk1 |
T |
C |
7: 121,768,481 (GRCm39) |
F535L |
probably damaging |
Het |
| Ppp1r9a |
A |
T |
6: 4,906,430 (GRCm39) |
E328D |
probably benign |
Het |
| Prss44 |
G |
A |
9: 110,646,379 (GRCm39) |
V369M |
probably benign |
Het |
| Rilp |
A |
G |
11: 75,401,798 (GRCm39) |
S193G |
probably benign |
Het |
| Ryr2 |
T |
C |
13: 11,776,201 (GRCm39) |
D1112G |
possibly damaging |
Het |
| Smc6 |
A |
G |
12: 11,333,141 (GRCm39) |
R238G |
possibly damaging |
Het |
| Spen |
A |
G |
4: 141,200,156 (GRCm39) |
S2824P |
probably damaging |
Het |
| Stk4 |
T |
C |
2: 163,925,663 (GRCm39) |
M77T |
probably damaging |
Het |
| Syne2 |
A |
T |
12: 75,995,838 (GRCm39) |
H2126L |
probably damaging |
Het |
| Thsd1 |
C |
T |
8: 22,749,003 (GRCm39) |
R625* |
probably null |
Het |
| Tle3 |
A |
T |
9: 61,320,138 (GRCm39) |
N522I |
probably damaging |
Het |
| Tmcc1 |
C |
A |
6: 116,020,763 (GRCm39) |
E230* |
probably null |
Het |
| Vmn2r90 |
T |
C |
17: 17,953,596 (GRCm39) |
S587P |
probably benign |
Het |
| Wt1 |
A |
T |
2: 104,957,161 (GRCm39) |
Q7L |
probably benign |
Het |
| Zfhx2 |
T |
C |
14: 55,300,306 (GRCm39) |
I2482V |
probably benign |
Het |
| Zfpm2 |
A |
T |
15: 40,959,487 (GRCm39) |
I189F |
probably benign |
Het |
|
| Other mutations in Rusc2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01358:Rusc2
|
APN |
4 |
43,426,116 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL01474:Rusc2
|
APN |
4 |
43,416,434 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01541:Rusc2
|
APN |
4 |
43,415,840 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL01628:Rusc2
|
APN |
4 |
43,425,729 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01969:Rusc2
|
APN |
4 |
43,415,738 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02030:Rusc2
|
APN |
4 |
43,416,095 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
IGL02079:Rusc2
|
APN |
4 |
43,425,668 (GRCm39) |
missense |
probably benign |
|
|
IGL02115:Rusc2
|
APN |
4 |
43,426,136 (GRCm39) |
splice site |
probably benign |
|
|
IGL02122:Rusc2
|
APN |
4 |
43,421,685 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
IGL02350:Rusc2
|
APN |
4 |
43,425,351 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
IGL02357:Rusc2
|
APN |
4 |
43,425,351 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
IGL02437:Rusc2
|
APN |
4 |
43,415,545 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02930:Rusc2
|
APN |
4 |
43,416,376 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03154:Rusc2
|
APN |
4 |
43,425,806 (GRCm39) |
missense |
probably benign |
0.00 |
|
P0026:Rusc2
|
UTSW |
4 |
43,415,840 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0036:Rusc2
|
UTSW |
4 |
43,424,009 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0068:Rusc2
|
UTSW |
4 |
43,424,100 (GRCm39) |
splice site |
probably benign |
|
|
R0068:Rusc2
|
UTSW |
4 |
43,424,100 (GRCm39) |
splice site |
probably benign |
|
|
R0114:Rusc2
|
UTSW |
4 |
43,422,055 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0255:Rusc2
|
UTSW |
4 |
43,423,954 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0471:Rusc2
|
UTSW |
4 |
43,425,486 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1381:Rusc2
|
UTSW |
4 |
43,416,137 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1413:Rusc2
|
UTSW |
4 |
43,416,568 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1416:Rusc2
|
UTSW |
4 |
43,421,617 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R1731:Rusc2
|
UTSW |
4 |
43,426,046 (GRCm39) |
missense |
probably benign |
|
|
R1864:Rusc2
|
UTSW |
4 |
43,421,719 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R1897:Rusc2
|
UTSW |
4 |
43,421,749 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2010:Rusc2
|
UTSW |
4 |
43,415,212 (GRCm39) |
missense |
probably benign |
0.06 |
|
R2212:Rusc2
|
UTSW |
4 |
43,415,935 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2275:Rusc2
|
UTSW |
4 |
43,416,260 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2885:Rusc2
|
UTSW |
4 |
43,415,456 (GRCm39) |
missense |
probably benign |
0.28 |
|
R2886:Rusc2
|
UTSW |
4 |
43,415,456 (GRCm39) |
missense |
probably benign |
0.28 |
|
R3412:Rusc2
|
UTSW |
4 |
43,415,935 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3413:Rusc2
|
UTSW |
4 |
43,415,935 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3414:Rusc2
|
UTSW |
4 |
43,415,935 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3852:Rusc2
|
UTSW |
4 |
43,416,424 (GRCm39) |
missense |
probably benign |
0.45 |
|
R4135:Rusc2
|
UTSW |
4 |
43,425,563 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R4272:Rusc2
|
UTSW |
4 |
43,415,533 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4574:Rusc2
|
UTSW |
4 |
43,416,080 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4888:Rusc2
|
UTSW |
4 |
43,423,942 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5010:Rusc2
|
UTSW |
4 |
43,415,926 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5071:Rusc2
|
UTSW |
4 |
43,415,240 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5131:Rusc2
|
UTSW |
4 |
43,414,948 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5177:Rusc2
|
UTSW |
4 |
43,421,805 (GRCm39) |
splice site |
probably null |
|
|
R5540:Rusc2
|
UTSW |
4 |
43,423,975 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5561:Rusc2
|
UTSW |
4 |
43,415,932 (GRCm39) |
nonsense |
probably null |
|
|
R5628:Rusc2
|
UTSW |
4 |
43,425,348 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5645:Rusc2
|
UTSW |
4 |
43,425,758 (GRCm39) |
missense |
probably benign |
0.06 |
|
R6129:Rusc2
|
UTSW |
4 |
43,424,271 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6362:Rusc2
|
UTSW |
4 |
43,416,416 (GRCm39) |
missense |
probably benign |
0.30 |
|
R6633:Rusc2
|
UTSW |
4 |
43,414,852 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6980:Rusc2
|
UTSW |
4 |
43,422,846 (GRCm39) |
missense |
probably benign |
0.35 |
|
R7491:Rusc2
|
UTSW |
4 |
43,426,528 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7641:Rusc2
|
UTSW |
4 |
43,425,335 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R7710:Rusc2
|
UTSW |
4 |
43,416,119 (GRCm39) |
missense |
probably benign |
0.07 |
|
R8052:Rusc2
|
UTSW |
4 |
43,421,851 (GRCm39) |
missense |
probably benign |
|
|
R8061:Rusc2
|
UTSW |
4 |
43,422,492 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8127:Rusc2
|
UTSW |
4 |
43,423,747 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R8319:Rusc2
|
UTSW |
4 |
43,425,378 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8355:Rusc2
|
UTSW |
4 |
43,422,846 (GRCm39) |
missense |
probably benign |
0.35 |
|
R8397:Rusc2
|
UTSW |
4 |
43,424,206 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8455:Rusc2
|
UTSW |
4 |
43,422,846 (GRCm39) |
missense |
probably benign |
0.35 |
|
R8553:Rusc2
|
UTSW |
4 |
43,416,508 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8725:Rusc2
|
UTSW |
4 |
43,401,351 (GRCm39) |
intron |
probably benign |
|
|
R8725:Rusc2
|
UTSW |
4 |
43,415,396 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8727:Rusc2
|
UTSW |
4 |
43,401,351 (GRCm39) |
intron |
probably benign |
|
|
R8834:Rusc2
|
UTSW |
4 |
43,416,431 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9295:Rusc2
|
UTSW |
4 |
43,416,382 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9483:Rusc2
|
UTSW |
4 |
43,415,897 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9666:Rusc2
|
UTSW |
4 |
43,416,262 (GRCm39) |
missense |
probably benign |
0.21 |
|
R9705:Rusc2
|
UTSW |
4 |
43,424,936 (GRCm39) |
missense |
probably benign |
0.00 |
|
X0025:Rusc2
|
UTSW |
4 |
43,422,226 (GRCm39) |
missense |
probably benign |
0.00 |
|
X0066:Rusc2
|
UTSW |
4 |
43,422,204 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CTGTTGATGCCCTTGTTGGAAC -3'
(R):5'- TCACCAGTGCTGCTGTCATG -3'
Sequencing Primer
(F):5'- TCCAGAATGGATAGCCCCC -3'
(R):5'- TGCTGTCATGCAGGTCAC -3'
|
| Posted On |
2019-11-12 |
Incidental Mutation