Incidental Mutation 'R7718:Dsc2'
| ID |
595075 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dsc2
|
| Ensembl Gene |
ENSMUSG00000024331 |
| Gene Name |
desmocollin 2 |
| Synonyms |
Dsc2b, Dsc2a |
| MMRRC Submission |
045775-MU
|
| Accession Numbers |
Genbank: NM_013505; MGI: 103221 |
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7718 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
18 |
| Chromosomal Location |
20030633-20059554 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 20041778 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Asparagine
at position 480
(I480N)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000042905
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000039247]
[ENSMUST00000075214]
[ENSMUST00000128464]
|
| AlphaFold |
P55292 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000039247
AA Change: I480N
PolyPhen 2
Score 0.981 (Sensitivity: 0.75; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000042905
Gene: ENSMUSG00000024331
AA Change: I480N
| Domain | Start | End | E-Value | Type |
|---|
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
CA
|
156 |
241 |
4.66e-11 |
SMART |
|
CA
|
265 |
353 |
1.87e-24 |
SMART |
|
low complexity region
|
358 |
372 |
N/A |
INTRINSIC |
|
CA
|
376 |
470 |
1.27e-12 |
SMART |
|
CA
|
493 |
575 |
4.14e-17 |
SMART |
|
CA
|
594 |
676 |
1.49e-1 |
SMART |
|
transmembrane domain
|
696 |
718 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000075214
AA Change: I480N
PolyPhen 2
Score 0.985 (Sensitivity: 0.74; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000074702
Gene: ENSMUSG00000024331
AA Change: I480N
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
28 |
N/A |
INTRINSIC |
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
CA
|
156 |
241 |
4.66e-11 |
SMART |
|
CA
|
265 |
353 |
1.87e-24 |
SMART |
|
low complexity region
|
358 |
372 |
N/A |
INTRINSIC |
|
CA
|
376 |
470 |
1.27e-12 |
SMART |
|
CA
|
493 |
575 |
4.14e-17 |
SMART |
|
CA
|
594 |
676 |
1.49e-1 |
SMART |
|
transmembrane domain
|
696 |
718 |
N/A |
INTRINSIC |
|
Pfam:Cadherin_C
|
730 |
901 |
3.7e-9 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000128464
|
| SMART Domains |
Protein: ENSMUSP00000123010
Gene: ENSMUSG00000024331
| Domain | Start | End | E-Value | Type |
|---|
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000155407
|
| SMART Domains |
Protein: ENSMUSP00000116063
Gene: ENSMUSG00000024331
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1l3wa5
|
2 |
71 |
2e-3 |
SMART |
|
Blast:CA
|
2 |
76 |
2e-47 |
BLAST |
|
transmembrane domain
|
96 |
118 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.6329 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
99% (77/78) |
| MGI Phenotype |
FUNCTION: This gene encodes a member of the desmocollin protein subfamily. Desmocollins are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
|
| Allele List at MGI |
All alleles(2) : Targeted, other(2) |
| Other mutations in this stock |
Total: 78 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4921507P07Rik |
G |
A |
6: 50,589,098 (GRCm38) |
|
probably null |
Het |
| 9530053A07Rik |
T |
C |
7: 28,147,201 (GRCm38) |
F1106S |
probably damaging |
Het |
| A430033K04Rik |
A |
T |
5: 138,647,860 (GRCm38) |
H669L |
possibly damaging |
Het |
| A930017K11Rik |
T |
A |
17: 25,947,024 (GRCm38) |
R430* |
probably null |
Het |
| Abcb1a |
A |
T |
5: 8,715,788 (GRCm38) |
N700I |
probably damaging |
Het |
| Abcc6 |
T |
C |
7: 45,977,392 (GRCm38) |
K1414E |
possibly damaging |
Het |
| Adcy5 |
T |
C |
16: 35,280,415 (GRCm38) |
V779A |
probably benign |
Het |
| Agap2 |
A |
G |
10: 127,079,865 (GRCm38) |
S82G |
possibly damaging |
Het |
| Aldh1l1 |
A |
G |
6: 90,598,323 (GRCm38) |
N864S |
probably damaging |
Het |
| Ang2 |
A |
T |
14: 51,195,760 (GRCm38) |
V55E |
probably benign |
Het |
| Ank2 |
A |
G |
3: 126,965,013 (GRCm38) |
M179T |
possibly damaging |
Het |
| Atrnl1 |
T |
A |
19: 57,740,183 (GRCm38) |
C1090* |
probably null |
Het |
| Atxn1l |
A |
G |
8: 109,733,234 (GRCm38) |
L132P |
probably damaging |
Het |
| Bptf |
A |
G |
11: 107,081,456 (GRCm38) |
V862A |
possibly damaging |
Het |
| Capn11 |
C |
A |
17: 45,643,781 (GRCm38) |
K143N |
probably damaging |
Het |
| Card6 |
A |
G |
15: 5,099,787 (GRCm38) |
V709A |
possibly damaging |
Het |
| Cavin4 |
C |
T |
4: 48,671,984 (GRCm38) |
A143V |
probably benign |
Het |
| Cntn5 |
A |
G |
9: 9,984,128 (GRCm38) |
I160T |
probably benign |
Het |
| Cyp2c40 |
T |
A |
19: 39,767,338 (GRCm38) |
N511Y |
probably benign |
Het |
| Elf2 |
G |
T |
3: 51,265,964 (GRCm38) |
|
probably benign |
Het |
| Enoph1 |
T |
C |
5: 100,062,160 (GRCm38) |
V133A |
possibly damaging |
Het |
| Ezh2 |
A |
T |
6: 47,554,191 (GRCm38) |
D186E |
probably benign |
Het |
| Fam196b |
T |
C |
11: 34,402,539 (GRCm38) |
S194P |
probably benign |
Het |
| Gfra1 |
T |
C |
19: 58,453,457 (GRCm38) |
D14G |
possibly damaging |
Het |
| Gm9573 |
T |
C |
17: 35,622,836 (GRCm38) |
T153A |
unknown |
Het |
| Gmip |
C |
T |
8: 69,817,733 (GRCm38) |
R698W |
probably damaging |
Het |
| Grk4 |
A |
G |
5: 34,694,816 (GRCm38) |
N135D |
probably benign |
Het |
| Hspb6 |
A |
G |
7: 30,554,347 (GRCm38) |
D95G |
probably benign |
Het |
| Htatip2 |
T |
G |
7: 49,770,884 (GRCm38) |
H159Q |
possibly damaging |
Het |
| Igfn1 |
T |
C |
1: 135,969,036 (GRCm38) |
E1264G |
probably benign |
Het |
| Katnb1 |
T |
A |
8: 95,095,208 (GRCm38) |
V223E |
possibly damaging |
Het |
| Klra6 |
AGG |
AG |
6: 130,013,352 (GRCm38) |
|
probably null |
Het |
| Masp2 |
C |
T |
4: 148,602,747 (GRCm38) |
R29C |
probably damaging |
Het |
| Mcm3 |
A |
T |
1: 20,817,274 (GRCm38) |
C123* |
probably null |
Het |
| Mdn1 |
T |
C |
4: 32,718,420 (GRCm38) |
V2225A |
probably damaging |
Het |
| Me1 |
A |
G |
9: 86,679,900 (GRCm38) |
L44S |
probably damaging |
Het |
| Mlxip |
A |
G |
5: 123,445,514 (GRCm38) |
N380S |
probably benign |
Het |
| Myh14 |
C |
T |
7: 44,661,040 (GRCm38) |
V140I |
probably damaging |
Het |
| Myocd |
A |
T |
11: 65,218,626 (GRCm38) |
D106E |
probably damaging |
Het |
| Oat |
T |
C |
7: 132,558,259 (GRCm38) |
I411V |
probably benign |
Het |
| Olfr1085 |
A |
G |
2: 86,658,029 (GRCm38) |
V143A |
probably benign |
Het |
| Olfr483 |
T |
C |
7: 108,103,648 (GRCm38) |
V113A |
probably benign |
Het |
| Olfr715 |
A |
T |
7: 107,128,718 (GRCm38) |
V225D |
probably damaging |
Het |
| Orc2 |
A |
T |
1: 58,480,317 (GRCm38) |
H246Q |
possibly damaging |
Het |
| Pank4 |
A |
G |
4: 154,974,643 (GRCm38) |
E411G |
probably damaging |
Het |
| Patl2 |
A |
T |
2: 122,126,774 (GRCm38) |
|
probably null |
Het |
| Pcdhb15 |
A |
G |
18: 37,475,163 (GRCm38) |
N483D |
probably damaging |
Het |
| Pcdhb20 |
A |
G |
18: 37,505,651 (GRCm38) |
D410G |
probably damaging |
Het |
| Pdcl2 |
A |
G |
5: 76,317,999 (GRCm38) |
C125R |
probably damaging |
Het |
| Peli3 |
C |
G |
19: 4,934,556 (GRCm38) |
|
probably null |
Het |
| Pkd1 |
A |
G |
17: 24,586,500 (GRCm38) |
D3313G |
probably benign |
Het |
| Plec |
A |
C |
15: 76,177,439 (GRCm38) |
M2766R |
probably damaging |
Het |
| Ppargc1a |
C |
T |
5: 51,498,162 (GRCm38) |
V99M |
probably damaging |
Het |
| Psg19 |
G |
A |
7: 18,792,443 (GRCm38) |
A374V |
probably benign |
Het |
| Psmd7 |
A |
T |
8: 107,586,629 (GRCm38) |
F54L |
possibly damaging |
Het |
| Ptbp2 |
C |
T |
3: 119,720,988 (GRCm38) |
G397R |
probably null |
Het |
| Ranbp3 |
A |
G |
17: 56,696,718 (GRCm38) |
D39G |
probably damaging |
Het |
| Rcor3 |
T |
C |
1: 192,101,721 (GRCm38) |
T406A |
probably benign |
Het |
| Rhbdl2 |
T |
A |
4: 123,824,919 (GRCm38) |
I222K |
probably damaging |
Het |
| Ripk2 |
T |
C |
4: 16,151,968 (GRCm38) |
N197S |
possibly damaging |
Het |
| Rpia |
A |
T |
6: 70,766,618 (GRCm38) |
M283K |
probably damaging |
Het |
| Rps6kc1 |
T |
C |
1: 190,871,825 (GRCm38) |
D200G |
probably benign |
Het |
| Sipa1l1 |
A |
T |
12: 82,342,497 (GRCm38) |
K499M |
probably damaging |
Het |
| Slc5a4b |
A |
G |
10: 76,070,573 (GRCm38) |
L404P |
probably damaging |
Het |
| Son |
AGAACCCCCAGCCGCAGGAGCCGAACCCCCAGCCGCAGGAGCCGAACCCCCAGCCGCAGGAGCCGAACCCCCAGCCG |
AGAACCCCCAGCCGCAGGAGCCGAACCCCCAGCCGCAGGAGCCGAACCCCCAGCCG |
16: 91,660,334 (GRCm38) |
|
probably benign |
Het |
| St7 |
A |
C |
6: 17,854,999 (GRCm38) |
T312P |
probably damaging |
Het |
| Strbp |
T |
C |
2: 37,625,282 (GRCm38) |
E244G |
probably damaging |
Het |
| Tbc1d8 |
T |
G |
1: 39,376,980 (GRCm38) |
T871P |
probably benign |
Het |
| Tcp1 |
T |
A |
17: 12,922,162 (GRCm38) |
I286N |
probably damaging |
Het |
| Tead3 |
C |
A |
17: 28,333,517 (GRCm38) |
V327F |
probably damaging |
Het |
| Tmem132c |
A |
T |
5: 127,563,440 (GRCm38) |
T892S |
probably benign |
Het |
| Trmt2a |
T |
C |
16: 18,250,623 (GRCm38) |
S65P |
probably benign |
Het |
| Ubp1 |
A |
G |
9: 113,973,529 (GRCm38) |
N479S |
possibly damaging |
Het |
| Ubtfl1 |
A |
T |
9: 18,409,231 (GRCm38) |
L18F |
possibly damaging |
Het |
| Uevld |
T |
G |
7: 46,938,056 (GRCm38) |
M299L |
probably benign |
Het |
| Unc13b |
T |
A |
4: 43,173,854 (GRCm38) |
Y1561N |
unknown |
Het |
| Ylpm1 |
A |
G |
12: 85,029,122 (GRCm38) |
K874E |
probably damaging |
Het |
| Zbtb37 |
G |
A |
1: 161,032,232 (GRCm38) |
R168W |
possibly damaging |
Het |
|
| Other mutations in Dsc2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00802:Dsc2
|
APN |
18 |
20,041,797 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL00826:Dsc2
|
APN |
18 |
20,035,315 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00852:Dsc2
|
APN |
18 |
20,034,683 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL01082:Dsc2
|
APN |
18 |
20,043,792 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01328:Dsc2
|
APN |
18 |
20,048,286 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL01338:Dsc2
|
APN |
18 |
20,047,157 (GRCm38) |
missense |
probably benign |
0.19 |
|
IGL01727:Dsc2
|
APN |
18 |
20,038,200 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL01766:Dsc2
|
APN |
18 |
20,046,342 (GRCm38) |
missense |
possibly damaging |
0.56 |
|
IGL02228:Dsc2
|
APN |
18 |
20,043,733 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02560:Dsc2
|
APN |
18 |
20,045,539 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02794:Dsc2
|
APN |
18 |
20,041,731 (GRCm38) |
missense |
probably damaging |
1.00 |
|
3-1:Dsc2
|
UTSW |
18 |
20,047,079 (GRCm38) |
missense |
possibly damaging |
0.60 |
|
PIT4305001:Dsc2
|
UTSW |
18 |
20,046,243 (GRCm38) |
missense |
probably damaging |
0.96 |
|
PIT4431001:Dsc2
|
UTSW |
18 |
20,046,277 (GRCm38) |
nonsense |
probably null |
|
|
R0288:Dsc2
|
UTSW |
18 |
20,033,120 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0542:Dsc2
|
UTSW |
18 |
20,051,226 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0562:Dsc2
|
UTSW |
18 |
20,041,537 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0697:Dsc2
|
UTSW |
18 |
20,041,452 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0940:Dsc2
|
UTSW |
18 |
20,050,059 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R1081:Dsc2
|
UTSW |
18 |
20,033,295 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R1140:Dsc2
|
UTSW |
18 |
20,032,212 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1515:Dsc2
|
UTSW |
18 |
20,045,565 (GRCm38) |
missense |
probably benign |
0.40 |
|
R1515:Dsc2
|
UTSW |
18 |
20,034,701 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1558:Dsc2
|
UTSW |
18 |
20,050,151 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1654:Dsc2
|
UTSW |
18 |
20,046,246 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2061:Dsc2
|
UTSW |
18 |
20,032,399 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R2089:Dsc2
|
UTSW |
18 |
20,033,294 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R2091:Dsc2
|
UTSW |
18 |
20,033,294 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R2091:Dsc2
|
UTSW |
18 |
20,033,294 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R2172:Dsc2
|
UTSW |
18 |
20,045,502 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2247:Dsc2
|
UTSW |
18 |
20,035,312 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2472:Dsc2
|
UTSW |
18 |
20,045,469 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2927:Dsc2
|
UTSW |
18 |
20,045,501 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3611:Dsc2
|
UTSW |
18 |
20,032,351 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R3961:Dsc2
|
UTSW |
18 |
20,051,227 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R3963:Dsc2
|
UTSW |
18 |
20,051,227 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R4353:Dsc2
|
UTSW |
18 |
20,050,068 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4362:Dsc2
|
UTSW |
18 |
20,050,157 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4612:Dsc2
|
UTSW |
18 |
20,041,819 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4613:Dsc2
|
UTSW |
18 |
20,041,819 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4752:Dsc2
|
UTSW |
18 |
20,038,222 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4946:Dsc2
|
UTSW |
18 |
20,050,157 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5056:Dsc2
|
UTSW |
18 |
20,050,142 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5267:Dsc2
|
UTSW |
18 |
20,034,583 (GRCm38) |
critical splice donor site |
probably null |
|
|
R5445:Dsc2
|
UTSW |
18 |
20,035,303 (GRCm38) |
missense |
possibly damaging |
0.76 |
|
R5507:Dsc2
|
UTSW |
18 |
20,046,279 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R5575:Dsc2
|
UTSW |
18 |
20,035,390 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5781:Dsc2
|
UTSW |
18 |
20,032,510 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6102:Dsc2
|
UTSW |
18 |
20,047,108 (GRCm38) |
missense |
probably benign |
0.01 |
|
R6129:Dsc2
|
UTSW |
18 |
20,045,430 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R6362:Dsc2
|
UTSW |
18 |
20,035,463 (GRCm38) |
nonsense |
probably null |
|
|
R6433:Dsc2
|
UTSW |
18 |
20,051,175 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6513:Dsc2
|
UTSW |
18 |
20,046,238 (GRCm38) |
missense |
probably benign |
|
|
R6615:Dsc2
|
UTSW |
18 |
20,032,519 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R6619:Dsc2
|
UTSW |
18 |
20,032,278 (GRCm38) |
missense |
probably benign |
0.22 |
|
R6665:Dsc2
|
UTSW |
18 |
20,050,148 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6961:Dsc2
|
UTSW |
18 |
20,038,222 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7179:Dsc2
|
UTSW |
18 |
20,035,275 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7275:Dsc2
|
UTSW |
18 |
20,051,179 (GRCm38) |
nonsense |
probably null |
|
|
R7352:Dsc2
|
UTSW |
18 |
20,035,335 (GRCm38) |
missense |
probably benign |
0.39 |
|
R7386:Dsc2
|
UTSW |
18 |
20,041,926 (GRCm38) |
missense |
possibly damaging |
0.84 |
|
R7496:Dsc2
|
UTSW |
18 |
20,035,394 (GRCm38) |
nonsense |
probably null |
|
|
R7510:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R7580:Dsc2
|
UTSW |
18 |
20,050,073 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7733:Dsc2
|
UTSW |
18 |
20,048,316 (GRCm38) |
missense |
probably benign |
0.16 |
|
R7733:Dsc2
|
UTSW |
18 |
20,048,315 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7818:Dsc2
|
UTSW |
18 |
20,050,132 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7852:Dsc2
|
UTSW |
18 |
20,046,285 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
R7998:Dsc2
|
UTSW |
18 |
20,034,663 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
R8029:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8030:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8031:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8032:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8059:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8060:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8061:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8062:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8063:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8082:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8090:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8114:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8115:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8116:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8117:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8118:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8328:Dsc2
|
UTSW |
18 |
20,032,519 (GRCm38) |
missense |
possibly damaging |
0.68 |
|
R8545:Dsc2
|
UTSW |
18 |
20,034,665 (GRCm38) |
nonsense |
probably null |
|
|
R9005:Dsc2
|
UTSW |
18 |
20,038,094 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9017:Dsc2
|
UTSW |
18 |
20,043,911 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9111:Dsc2
|
UTSW |
18 |
20,034,707 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9396:Dsc2
|
UTSW |
18 |
20,041,716 (GRCm38) |
nonsense |
probably null |
|
|
R9487:Dsc2
|
UTSW |
18 |
20,047,219 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9663:Dsc2
|
UTSW |
18 |
20,038,148 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1088:Dsc2
|
UTSW |
18 |
20,046,304 (GRCm38) |
missense |
probably damaging |
0.98 |
|
Z1176:Dsc2
|
UTSW |
18 |
20,035,299 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AACAGTGACCCACCCTCTTG -3'
(R):5'- TCTGGACTATGAAGAACGGC -3'
Sequencing Primer
(F):5'- TGTTAACCACAGTGAAGGAACAC -3'
(R):5'- GAACGGCAACAGGTGACCC -3'
|
| Posted On |
2019-11-12 |
Incidental Mutation