Incidental Mutation 'R7719:Prrc2b'
| ID |
595091 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Prrc2b
|
| Ensembl Gene |
ENSMUSG00000039262 |
| Gene Name |
proline-rich coiled-coil 2B |
| Synonyms |
5830434P21Rik, Bat2l |
| MMRRC Submission |
045776-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R7719 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
32041094-32124549 bp(+) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
T to A
at 32107280 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Cysteine to Stop codon
at position 1614
(C1614*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000064892
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000036691]
[ENSMUST00000069817]
|
| AlphaFold |
Q7TPM1 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000036691
AA Change: C927*
|
| SMART Domains |
Protein: ENSMUSP00000035734
Gene: ENSMUSG00000039262
AA Change: C927*
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:BAT2_N
|
1 |
194 |
2.7e-85 |
PFAM |
|
low complexity region
|
359 |
374 |
N/A |
INTRINSIC |
|
low complexity region
|
388 |
394 |
N/A |
INTRINSIC |
|
low complexity region
|
413 |
424 |
N/A |
INTRINSIC |
|
coiled coil region
|
494 |
544 |
N/A |
INTRINSIC |
|
low complexity region
|
600 |
621 |
N/A |
INTRINSIC |
|
low complexity region
|
638 |
656 |
N/A |
INTRINSIC |
|
low complexity region
|
885 |
900 |
N/A |
INTRINSIC |
|
low complexity region
|
992 |
1007 |
N/A |
INTRINSIC |
|
low complexity region
|
1112 |
1126 |
N/A |
INTRINSIC |
|
low complexity region
|
1218 |
1233 |
N/A |
INTRINSIC |
|
low complexity region
|
1257 |
1275 |
N/A |
INTRINSIC |
|
low complexity region
|
1402 |
1421 |
N/A |
INTRINSIC |
|
low complexity region
|
1425 |
1437 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000069817
AA Change: C1614*
|
| SMART Domains |
Protein: ENSMUSP00000064892
Gene: ENSMUSG00000039262
AA Change: C1614*
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:BAT2_N
|
1 |
191 |
3.1e-65 |
PFAM |
|
low complexity region
|
359 |
374 |
N/A |
INTRINSIC |
|
low complexity region
|
388 |
394 |
N/A |
INTRINSIC |
|
low complexity region
|
413 |
424 |
N/A |
INTRINSIC |
|
coiled coil region
|
494 |
544 |
N/A |
INTRINSIC |
|
low complexity region
|
600 |
621 |
N/A |
INTRINSIC |
|
low complexity region
|
638 |
656 |
N/A |
INTRINSIC |
|
low complexity region
|
960 |
977 |
N/A |
INTRINSIC |
|
low complexity region
|
1004 |
1018 |
N/A |
INTRINSIC |
|
low complexity region
|
1070 |
1094 |
N/A |
INTRINSIC |
|
low complexity region
|
1307 |
1325 |
N/A |
INTRINSIC |
|
low complexity region
|
1388 |
1401 |
N/A |
INTRINSIC |
|
low complexity region
|
1413 |
1426 |
N/A |
INTRINSIC |
|
low complexity region
|
1572 |
1587 |
N/A |
INTRINSIC |
|
low complexity region
|
1678 |
1693 |
N/A |
INTRINSIC |
|
low complexity region
|
1798 |
1812 |
N/A |
INTRINSIC |
|
low complexity region
|
1904 |
1919 |
N/A |
INTRINSIC |
|
low complexity region
|
1943 |
1961 |
N/A |
INTRINSIC |
|
low complexity region
|
2088 |
2107 |
N/A |
INTRINSIC |
|
low complexity region
|
2111 |
2123 |
N/A |
INTRINSIC |
|
low complexity region
|
2161 |
2174 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000128936
AA Change: C94*
|
| SMART Domains |
Protein: ENSMUSP00000121664
Gene: ENSMUSG00000039262
AA Change: C94*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
53 |
68 |
N/A |
INTRINSIC |
|
low complexity region
|
159 |
174 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000132459
AA Change: C854*
|
| SMART Domains |
Protein: ENSMUSP00000116429
Gene: ENSMUSG00000039262
AA Change: C854*
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:BAT2_N
|
1 |
119 |
9.8e-24 |
PFAM |
|
low complexity region
|
287 |
302 |
N/A |
INTRINSIC |
|
low complexity region
|
316 |
322 |
N/A |
INTRINSIC |
|
low complexity region
|
341 |
352 |
N/A |
INTRINSIC |
|
coiled coil region
|
421 |
471 |
N/A |
INTRINSIC |
|
low complexity region
|
528 |
549 |
N/A |
INTRINSIC |
|
low complexity region
|
566 |
584 |
N/A |
INTRINSIC |
|
low complexity region
|
813 |
828 |
N/A |
INTRINSIC |
|
low complexity region
|
920 |
935 |
N/A |
INTRINSIC |
|
low complexity region
|
1040 |
1054 |
N/A |
INTRINSIC |
|
low complexity region
|
1146 |
1161 |
N/A |
INTRINSIC |
|
low complexity region
|
1185 |
1203 |
N/A |
INTRINSIC |
|
low complexity region
|
1330 |
1349 |
N/A |
INTRINSIC |
|
low complexity region
|
1353 |
1365 |
N/A |
INTRINSIC |
|
low complexity region
|
1403 |
1416 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000156313
AA Change: C166*
|
| SMART Domains |
Protein: ENSMUSP00000114994
Gene: ENSMUSG00000039262
AA Change: C166*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
125 |
140 |
N/A |
INTRINSIC |
|
low complexity region
|
231 |
246 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
99% (67/68) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 71 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acbd6 |
T |
A |
1: 155,562,758 (GRCm39) |
L253H |
probably damaging |
Het |
| Adam11 |
T |
C |
11: 102,663,303 (GRCm39) |
V238A |
probably benign |
Het |
| Amer3 |
A |
T |
1: 34,628,083 (GRCm39) |
H774L |
possibly damaging |
Het |
| Anapc15 |
T |
C |
7: 101,550,236 (GRCm39) |
L150P |
unknown |
Het |
| Ano8 |
G |
T |
8: 71,935,784 (GRCm39) |
T278K |
possibly damaging |
Het |
| Atg16l2 |
T |
C |
7: 100,939,074 (GRCm39) |
K618E |
probably damaging |
Het |
| Casz1 |
C |
T |
4: 149,028,981 (GRCm39) |
S1142L |
probably damaging |
Het |
| Ccdc30 |
T |
A |
4: 119,190,813 (GRCm39) |
E471D |
probably damaging |
Het |
| Cks1b |
T |
C |
3: 89,323,635 (GRCm39) |
N45D |
probably benign |
Het |
| Clasrp |
T |
C |
7: 19,321,769 (GRCm39) |
T296A |
probably damaging |
Het |
| Cluap1 |
C |
T |
16: 3,727,467 (GRCm39) |
|
probably null |
Het |
| Cntn5 |
T |
A |
9: 9,704,903 (GRCm39) |
D632V |
probably damaging |
Het |
| Cntnap3 |
G |
A |
13: 64,920,591 (GRCm39) |
Q593* |
probably null |
Het |
| Col18a1 |
A |
T |
10: 76,913,846 (GRCm39) |
I457K |
probably benign |
Het |
| Crybb3 |
G |
T |
5: 113,223,834 (GRCm39) |
Q192K |
probably damaging |
Het |
| Cyb561d2 |
C |
T |
9: 107,417,383 (GRCm39) |
A123T |
probably benign |
Het |
| Cyp2b13 |
C |
T |
7: 25,795,095 (GRCm39) |
A442V |
probably damaging |
Het |
| Cyp2j9 |
G |
A |
4: 96,457,079 (GRCm39) |
T464I |
probably benign |
Het |
| Cyp4a29 |
G |
A |
4: 115,108,137 (GRCm39) |
G320R |
possibly damaging |
Het |
| Dbp |
T |
C |
7: 45,359,174 (GRCm39) |
I283T |
probably damaging |
Het |
| Efcab3 |
T |
C |
11: 105,002,674 (GRCm39) |
I303T |
probably benign |
Het |
| Efcab8 |
T |
A |
2: 153,629,665 (GRCm39) |
V166D |
|
Het |
| Efhc1 |
A |
T |
1: 21,049,744 (GRCm39) |
I535F |
probably benign |
Het |
| Epb41l3 |
A |
G |
17: 69,560,409 (GRCm39) |
I319V |
possibly damaging |
Het |
| Ewsr1 |
T |
C |
11: 5,035,900 (GRCm39) |
T193A |
unknown |
Het |
| Fam227a |
T |
C |
15: 79,504,913 (GRCm39) |
N510S |
possibly damaging |
Het |
| Frmpd1 |
T |
C |
4: 45,284,841 (GRCm39) |
C1221R |
possibly damaging |
Het |
| Gm6741 |
A |
C |
17: 91,544,472 (GRCm39) |
E78D |
probably benign |
Het |
| Gpam |
C |
T |
19: 55,070,102 (GRCm39) |
V385I |
probably damaging |
Het |
| Gpr55 |
A |
G |
1: 85,869,059 (GRCm39) |
V174A |
probably benign |
Het |
| Gsdmc |
T |
C |
15: 63,650,813 (GRCm39) |
|
probably null |
Het |
| Hmcn1 |
T |
A |
1: 150,441,080 (GRCm39) |
D5509V |
possibly damaging |
Het |
| Hoxc13 |
A |
T |
15: 102,830,293 (GRCm39) |
Q224L |
possibly damaging |
Het |
| Hunk |
A |
G |
16: 90,293,554 (GRCm39) |
D612G |
probably benign |
Het |
| Igsf3 |
G |
A |
3: 101,342,857 (GRCm39) |
R478H |
probably damaging |
Het |
| Itgb5 |
A |
G |
16: 33,740,486 (GRCm39) |
Q532R |
probably benign |
Het |
| Jph1 |
T |
C |
1: 17,162,215 (GRCm39) |
Y149C |
probably damaging |
Het |
| Lztfl1 |
T |
C |
9: 123,544,395 (GRCm39) |
D33G |
probably null |
Het |
| Mex3c |
G |
T |
18: 73,723,061 (GRCm39) |
A385S |
possibly damaging |
Het |
| Myo5a |
T |
A |
9: 75,051,366 (GRCm39) |
S320T |
probably benign |
Het |
| Nsun4 |
A |
T |
4: 115,909,617 (GRCm39) |
N314K |
possibly damaging |
Het |
| Omg |
T |
A |
11: 79,393,059 (GRCm39) |
E266D |
probably benign |
Het |
| Or4b12 |
A |
T |
2: 90,096,603 (GRCm39) |
M57K |
probably damaging |
Het |
| Paqr9 |
T |
A |
9: 95,442,829 (GRCm39) |
V273E |
possibly damaging |
Het |
| Phkg1 |
G |
A |
5: 129,902,699 (GRCm39) |
|
probably benign |
Het |
| Plekhm3 |
T |
C |
1: 64,960,901 (GRCm39) |
K452E |
probably benign |
Het |
| Plpbp |
T |
A |
8: 27,535,974 (GRCm39) |
I86N |
|
Het |
| Prl2c1 |
G |
T |
13: 28,035,780 (GRCm39) |
A51S |
probably damaging |
Het |
| Prmt8 |
A |
T |
6: 127,706,466 (GRCm39) |
H108Q |
probably damaging |
Het |
| Ptpdc1 |
A |
G |
13: 48,739,766 (GRCm39) |
V555A |
probably benign |
Het |
| Rassf9 |
A |
G |
10: 102,381,461 (GRCm39) |
D281G |
probably benign |
Het |
| Resf1 |
T |
C |
6: 149,228,853 (GRCm39) |
I633T |
probably benign |
Het |
| Rmnd1 |
T |
C |
10: 4,377,496 (GRCm39) |
D61G |
probably benign |
Het |
| Rsf1 |
GGCG |
GGCGACGGCCGCG |
7: 97,229,113 (GRCm39) |
|
probably benign |
Het |
| Ryr2 |
A |
G |
13: 11,745,229 (GRCm39) |
S2055P |
possibly damaging |
Het |
| Six5 |
G |
A |
7: 18,830,803 (GRCm39) |
A477T |
probably damaging |
Het |
| Speg |
A |
G |
1: 75,352,469 (GRCm39) |
E129G |
probably damaging |
Het |
| Stard10 |
C |
T |
7: 100,995,320 (GRCm39) |
A78V |
not run |
Het |
| Stard3 |
T |
C |
11: 98,266,502 (GRCm39) |
V127A |
probably benign |
Het |
| Svep1 |
G |
A |
4: 58,068,523 (GRCm39) |
P3088S |
probably damaging |
Het |
| Tbck |
A |
G |
3: 132,440,489 (GRCm39) |
D508G |
probably damaging |
Het |
| Tgm2 |
T |
A |
2: 157,985,038 (GRCm39) |
T23S |
probably damaging |
Het |
| Ttll10 |
G |
T |
4: 156,131,665 (GRCm39) |
|
probably null |
Het |
| Vcan |
A |
T |
13: 89,852,738 (GRCm39) |
S741T |
probably damaging |
Het |
| Vmn2r13 |
T |
C |
5: 109,319,618 (GRCm39) |
N454S |
probably benign |
Het |
| Vmn2r45 |
T |
A |
7: 8,486,460 (GRCm39) |
E276V |
probably damaging |
Het |
| Wnt8a |
T |
C |
18: 34,680,588 (GRCm39) |
W318R |
probably damaging |
Het |
| Zer1 |
A |
T |
2: 30,001,243 (GRCm39) |
L87H |
probably damaging |
Het |
| Zfp518a |
T |
A |
19: 40,901,212 (GRCm39) |
N380K |
probably benign |
Het |
| Zfp90 |
T |
C |
8: 107,145,725 (GRCm39) |
V19A |
probably damaging |
Het |
| Zkscan5 |
A |
C |
5: 145,157,676 (GRCm39) |
H726P |
probably damaging |
Het |
|
| Other mutations in Prrc2b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00156:Prrc2b
|
APN |
2 |
32,098,731 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00846:Prrc2b
|
APN |
2 |
32,089,109 (GRCm39) |
splice site |
probably benign |
|
|
IGL00977:Prrc2b
|
APN |
2 |
32,103,822 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL01372:Prrc2b
|
APN |
2 |
32,113,942 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01993:Prrc2b
|
APN |
2 |
32,114,057 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
IGL02097:Prrc2b
|
APN |
2 |
32,081,513 (GRCm39) |
splice site |
probably benign |
|
|
IGL02165:Prrc2b
|
APN |
2 |
32,104,652 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02184:Prrc2b
|
APN |
2 |
32,111,467 (GRCm39) |
missense |
probably benign |
0.19 |
|
IGL02238:Prrc2b
|
APN |
2 |
32,103,429 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02338:Prrc2b
|
APN |
2 |
32,104,047 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02399:Prrc2b
|
APN |
2 |
32,116,973 (GRCm39) |
nonsense |
probably null |
|
|
IGL02597:Prrc2b
|
APN |
2 |
32,109,625 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02729:Prrc2b
|
APN |
2 |
32,098,770 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02743:Prrc2b
|
APN |
2 |
32,084,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02815:Prrc2b
|
APN |
2 |
32,094,265 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03159:Prrc2b
|
APN |
2 |
32,084,498 (GRCm39) |
missense |
probably damaging |
0.98 |
|
BB002:Prrc2b
|
UTSW |
2 |
32,094,127 (GRCm39) |
missense |
probably damaging |
1.00 |
|
BB012:Prrc2b
|
UTSW |
2 |
32,094,127 (GRCm39) |
missense |
probably damaging |
1.00 |
|
FR4304:Prrc2b
|
UTSW |
2 |
32,111,179 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0082:Prrc2b
|
UTSW |
2 |
32,102,310 (GRCm39) |
splice site |
probably benign |
|
|
R0105:Prrc2b
|
UTSW |
2 |
32,103,323 (GRCm39) |
nonsense |
probably null |
|
|
R0276:Prrc2b
|
UTSW |
2 |
32,109,666 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0325:Prrc2b
|
UTSW |
2 |
32,089,103 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0436:Prrc2b
|
UTSW |
2 |
32,120,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0595:Prrc2b
|
UTSW |
2 |
32,073,189 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0607:Prrc2b
|
UTSW |
2 |
32,103,882 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0650:Prrc2b
|
UTSW |
2 |
32,119,267 (GRCm39) |
splice site |
probably benign |
|
|
R1282:Prrc2b
|
UTSW |
2 |
32,113,456 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1421:Prrc2b
|
UTSW |
2 |
32,090,990 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R1452:Prrc2b
|
UTSW |
2 |
32,084,997 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1535:Prrc2b
|
UTSW |
2 |
32,094,301 (GRCm39) |
missense |
probably benign |
0.06 |
|
R1709:Prrc2b
|
UTSW |
2 |
32,084,473 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1710:Prrc2b
|
UTSW |
2 |
32,102,234 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2094:Prrc2b
|
UTSW |
2 |
32,072,582 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2202:Prrc2b
|
UTSW |
2 |
32,113,476 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2203:Prrc2b
|
UTSW |
2 |
32,113,476 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2204:Prrc2b
|
UTSW |
2 |
32,113,476 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2428:Prrc2b
|
UTSW |
2 |
32,106,067 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2435:Prrc2b
|
UTSW |
2 |
32,109,741 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3439:Prrc2b
|
UTSW |
2 |
32,096,359 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4175:Prrc2b
|
UTSW |
2 |
32,108,820 (GRCm39) |
intron |
probably benign |
|
|
R4710:Prrc2b
|
UTSW |
2 |
32,083,869 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R4728:Prrc2b
|
UTSW |
2 |
32,120,637 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4791:Prrc2b
|
UTSW |
2 |
32,107,351 (GRCm39) |
splice site |
probably null |
|
|
R4876:Prrc2b
|
UTSW |
2 |
32,104,212 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4908:Prrc2b
|
UTSW |
2 |
32,116,330 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4997:Prrc2b
|
UTSW |
2 |
32,112,323 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5240:Prrc2b
|
UTSW |
2 |
32,096,408 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5276:Prrc2b
|
UTSW |
2 |
32,104,734 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5455:Prrc2b
|
UTSW |
2 |
32,111,355 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R5821:Prrc2b
|
UTSW |
2 |
32,102,144 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5835:Prrc2b
|
UTSW |
2 |
32,096,485 (GRCm39) |
missense |
probably benign |
0.18 |
|
R5958:Prrc2b
|
UTSW |
2 |
32,102,092 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6052:Prrc2b
|
UTSW |
2 |
32,102,297 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6218:Prrc2b
|
UTSW |
2 |
32,098,823 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6428:Prrc2b
|
UTSW |
2 |
32,116,508 (GRCm39) |
splice site |
probably null |
|
|
R6505:Prrc2b
|
UTSW |
2 |
32,112,332 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6812:Prrc2b
|
UTSW |
2 |
32,103,153 (GRCm39) |
missense |
probably benign |
0.30 |
|
R6826:Prrc2b
|
UTSW |
2 |
32,112,300 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6827:Prrc2b
|
UTSW |
2 |
32,090,963 (GRCm39) |
missense |
probably benign |
0.37 |
|
R7021:Prrc2b
|
UTSW |
2 |
32,111,498 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7078:Prrc2b
|
UTSW |
2 |
32,103,531 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7081:Prrc2b
|
UTSW |
2 |
32,103,075 (GRCm39) |
missense |
probably benign |
0.12 |
|
R7101:Prrc2b
|
UTSW |
2 |
32,117,005 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R7215:Prrc2b
|
UTSW |
2 |
32,119,309 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7228:Prrc2b
|
UTSW |
2 |
32,104,318 (GRCm39) |
nonsense |
probably null |
|
|
R7566:Prrc2b
|
UTSW |
2 |
32,084,402 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7925:Prrc2b
|
UTSW |
2 |
32,094,127 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7999:Prrc2b
|
UTSW |
2 |
32,084,426 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8099:Prrc2b
|
UTSW |
2 |
32,098,686 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8154:Prrc2b
|
UTSW |
2 |
32,108,689 (GRCm39) |
missense |
probably benign |
0.42 |
|
R8252:Prrc2b
|
UTSW |
2 |
32,109,392 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R8379:Prrc2b
|
UTSW |
2 |
32,104,666 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8485:Prrc2b
|
UTSW |
2 |
32,102,105 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R8845:Prrc2b
|
UTSW |
2 |
32,106,162 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8845:Prrc2b
|
UTSW |
2 |
32,102,105 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R8919:Prrc2b
|
UTSW |
2 |
32,104,953 (GRCm39) |
missense |
probably benign |
|
|
R8982:Prrc2b
|
UTSW |
2 |
32,102,134 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9065:Prrc2b
|
UTSW |
2 |
32,109,304 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9127:Prrc2b
|
UTSW |
2 |
32,103,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9217:Prrc2b
|
UTSW |
2 |
32,103,414 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9338:Prrc2b
|
UTSW |
2 |
32,098,779 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9344:Prrc2b
|
UTSW |
2 |
32,103,600 (GRCm39) |
missense |
probably benign |
0.28 |
|
R9386:Prrc2b
|
UTSW |
2 |
32,104,125 (GRCm39) |
missense |
probably benign |
|
|
R9601:Prrc2b
|
UTSW |
2 |
32,090,953 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9607:Prrc2b
|
UTSW |
2 |
32,098,794 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9670:Prrc2b
|
UTSW |
2 |
32,103,199 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9706:Prrc2b
|
UTSW |
2 |
32,107,300 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1088:Prrc2b
|
UTSW |
2 |
32,106,744 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Prrc2b
|
UTSW |
2 |
32,104,441 (GRCm39) |
missense |
probably benign |
0.03 |
|
Z1177:Prrc2b
|
UTSW |
2 |
32,116,364 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGCATCTCAAGCTGGTTTGG -3'
(R):5'- TGACATGGTGCAGAGGTTC -3'
Sequencing Primer
(F):5'- GGGTAGTAATATGACACTTTCCTAGG -3'
(R):5'- AACACTGACTCTGCTTGGG -3'
|
| Posted On |
2019-11-12 |
Incidental Mutation