Incidental Mutation 'R7720:Atm'
ID 595180
Institutional Source Beutler Lab
Gene Symbol Atm
Ensembl Gene ENSMUSG00000034218
Gene Name ataxia telangiectasia mutated
Synonyms C030026E19Rik
MMRRC Submission 067892-MU
Accession Numbers
Essential gene? Probably essential (E-score: 0.928) question?
Stock # R7720 (G1)
Quality Score 225.009
Status Validated
Chromosome 9
Chromosomal Location 53439149-53536740 bp(-) (GRCm38)
Type of Mutation missense
DNA Base Change (assembly) T to C at 53522239 bp (GRCm38)
Zygosity Heterozygous
Amino Acid Change Asparagine to Serine at position 237 (N237S)
Ref Sequence ENSEMBL: ENSMUSP00000113388 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000118282] [ENSMUST00000150244] [ENSMUST00000232179]
AlphaFold no structure available at present
Predicted Effect possibly damaging
Transcript: ENSMUST00000118282
AA Change: N237S

PolyPhen 2 Score 0.541 (Sensitivity: 0.88; Specificity: 0.91)
SMART Domains Protein: ENSMUSP00000113388
Gene: ENSMUSG00000034218
AA Change: N237S

DomainStartEndE-ValueType
TAN 1 166 5.07e-68 SMART
low complexity region 431 445 N/A INTRINSIC
low complexity region 830 846 N/A INTRINSIC
low complexity region 929 940 N/A INTRINSIC
SCOP:d1gw5a_ 1039 1568 2e-4 SMART
coiled coil region 1615 1644 N/A INTRINSIC
low complexity region 1650 1662 N/A INTRINSIC
Pfam:FAT 2102 2499 4.4e-50 PFAM
low complexity region 2587 2599 N/A INTRINSIC
PI3Kc 2723 3026 1.11e-117 SMART
FATC 3034 3066 3.71e-11 SMART
Predicted Effect probably benign
Transcript: ENSMUST00000150244
SMART Domains Protein: ENSMUSP00000115394
Gene: ENSMUSG00000034218

DomainStartEndE-ValueType
TAN 1 140 2.88e-40 SMART
Predicted Effect possibly damaging
Transcript: ENSMUST00000232179
AA Change: N237S

PolyPhen 2 Score 0.549 (Sensitivity: 0.88; Specificity: 0.91)
Coding Region Coverage
  • 1x: 100.0%
  • 3x: 99.9%
  • 10x: 99.7%
  • 20x: 99.1%
Validation Efficiency 100% (51/51)
MGI Phenotype FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. [provided by RefSeq, Aug 2010]
PHENOTYPE: Homozygotes for null mutations may exhibit locomotor abnormalities, motor learning deficits, growth retardation, sterility due to meiotic arrest, and susceptibility to thymic lymphomas. Mice homozygous for a kinase dead allele exhibit early embryonic lethality associated with genetic instability. [provided by MGI curators]
Allele List at MGI
Other mutations in this stock
Total: 53 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1810013L24Rik T A 16: 8,843,102 (GRCm38) C148S probably damaging Het
4921530L21Rik A G 14: 95,882,112 (GRCm38) R102G probably benign Het
A230050P20Rik C T 9: 20,868,859 (GRCm38) probably benign Het
Agap2 A G 10: 127,091,088 (GRCm38) D1018G probably damaging Het
Card6 G T 15: 5,098,423 (GRCm38) Q1164K unknown Het
Cped1 G A 6: 22,222,431 (GRCm38) C730Y probably damaging Het
Csmd1 A T 8: 15,931,108 (GRCm38) L2770Q probably damaging Het
Ctsw T C 19: 5,467,044 (GRCm38) T87A probably damaging Het
Dock4 T C 12: 40,806,975 (GRCm38) I1269T probably damaging Het
F11 T C 8: 45,252,090 (GRCm38) E138G possibly damaging Het
Fam124b A G 1: 80,200,257 (GRCm38) S342P probably damaging Het
Fam71d T C 12: 78,712,133 (GRCm38) S76P probably damaging Het
Gipr T C 7: 19,162,959 (GRCm38) I129V probably benign Het
Gm5415 T C 1: 32,546,097 (GRCm38) D244G probably benign Het
Gria4 A T 9: 4,464,288 (GRCm38) V558D probably damaging Het
Gsdme C T 6: 50,229,308 (GRCm38) G185E probably damaging Het
Hgd T A 16: 37,593,435 (GRCm38) D86E probably benign Het
Hmcn1 T A 1: 150,646,709 (GRCm38) H3480L probably benign Het
Hs2st1 T C 3: 144,454,022 (GRCm38) N127D probably damaging Het
Ilf3 A G 9: 21,399,537 (GRCm38) N599S possibly damaging Het
Itsn1 G A 16: 91,868,083 (GRCm38) G1132R unknown Het
Jakmip2 A G 18: 43,571,908 (GRCm38) S343P possibly damaging Het
Kif1b A G 4: 149,182,355 (GRCm38) V1670A probably benign Het
Lman2 A T 13: 55,353,077 (GRCm38) probably null Het
Ltbp1 A T 17: 75,385,124 (GRCm38) Y1579F probably damaging Het
Mon2 G A 10: 123,032,588 (GRCm38) A520V probably benign Het
Mrpl10 T G 11: 97,047,537 (GRCm38) V171G possibly damaging Het
Mrps27 A T 13: 99,401,330 (GRCm38) T153S unknown Het
Muc5ac G C 7: 141,809,303 (GRCm38) G2117A unknown Het
Nlrp10 A G 7: 108,924,488 (GRCm38) V595A probably benign Het
Nol4 A T 18: 23,040,023 (GRCm38) M7K probably benign Het
Oasl1 G A 5: 114,929,921 (GRCm38) S188N probably damaging Het
Olfr193 T C 16: 59,109,771 (GRCm38) I280V probably benign Het
Olfr709-ps1 C A 7: 106,927,411 (GRCm38) G16V probably benign Het
Pcdhga2 A G 18: 37,669,940 (GRCm38) Y279C probably damaging Het
Pfpl C T 19: 12,429,174 (GRCm38) A263V probably benign Het
Phf3 T G 1: 30,829,857 (GRCm38) K703N probably damaging Het
Pik3ca C G 3: 32,436,218 (GRCm38) P5A probably damaging Het
Plekha6 T C 1: 133,293,707 (GRCm38) V987A probably damaging Het
Ppp3ca T A 3: 136,890,489 (GRCm38) I305N probably damaging Het
Prex2 A G 1: 11,181,937 (GRCm38) K1069E possibly damaging Het
Prss50 T C 9: 110,861,335 (GRCm38) V182A probably damaging Het
Ptprg A G 14: 12,211,703 (GRCm38) N995S probably benign Het
Robo2 C A 16: 73,897,015 (GRCm38) G1375V probably benign Het
Rtl1 T C 12: 109,594,430 (GRCm38) Y325C possibly damaging Het
Shcbp1 A C 8: 4,748,720 (GRCm38) S400A probably damaging Het
Sirpb1c T A 3: 15,832,072 (GRCm38) Y380F probably benign Het
Tbl2 G C 5: 135,159,475 (GRCm38) L374F probably damaging Het
Tpr C A 1: 150,429,532 (GRCm38) A1524E possibly damaging Het
Vmn2r45 T A 7: 8,483,461 (GRCm38) E276V probably damaging Het
Vps16 C T 2: 130,441,703 (GRCm38) Q606* probably null Het
Vstm5 A T 9: 15,239,356 (GRCm38) Q29L probably benign Het
Wipi1 G T 11: 109,582,423 (GRCm38) S250Y probably damaging Het
Other mutations in Atm
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00090:Atm APN 9 53,524,443 (GRCm38) missense probably damaging 1.00
IGL00466:Atm APN 9 53,499,112 (GRCm38) splice site probably benign
IGL00567:Atm APN 9 53,503,116 (GRCm38) nonsense probably null
IGL00702:Atm APN 9 53,511,831 (GRCm38) missense probably benign 0.02
IGL00743:Atm APN 9 53,513,116 (GRCm38) missense probably benign 0.00
IGL00771:Atm APN 9 53,493,054 (GRCm38) missense probably benign 0.01
IGL00773:Atm APN 9 53,522,144 (GRCm38) missense probably benign 0.00
IGL00819:Atm APN 9 53,518,531 (GRCm38) missense probably damaging 1.00
IGL00864:Atm APN 9 53,533,933 (GRCm38) missense probably damaging 0.99
IGL00985:Atm APN 9 53,459,816 (GRCm38) missense probably damaging 0.98
IGL01109:Atm APN 9 53,490,293 (GRCm38) missense probably damaging 1.00
IGL01120:Atm APN 9 53,461,122 (GRCm38) critical splice acceptor site probably null
IGL01369:Atm APN 9 53,515,317 (GRCm38) missense probably benign
IGL01374:Atm APN 9 53,531,724 (GRCm38) missense possibly damaging 0.58
IGL01406:Atm APN 9 53,439,746 (GRCm38) makesense probably null
IGL01409:Atm APN 9 53,499,171 (GRCm38) missense probably benign 0.01
IGL01434:Atm APN 9 53,507,807 (GRCm38) missense probably benign 0.04
IGL01486:Atm APN 9 53,510,213 (GRCm38) missense probably benign
IGL01583:Atm APN 9 53,484,247 (GRCm38) splice site probably benign
IGL01861:Atm APN 9 53,494,612 (GRCm38) missense probably null 0.89
IGL01865:Atm APN 9 53,461,002 (GRCm38) missense probably damaging 1.00
IGL02026:Atm APN 9 53,442,417 (GRCm38) splice site probably null
IGL02072:Atm APN 9 53,459,796 (GRCm38) missense probably benign 0.01
IGL02075:Atm APN 9 53,527,237 (GRCm38) missense probably damaging 1.00
IGL02127:Atm APN 9 53,487,983 (GRCm38) missense probably damaging 1.00
IGL02175:Atm APN 9 53,480,665 (GRCm38) missense probably damaging 0.99
IGL02246:Atm APN 9 53,527,185 (GRCm38) missense probably benign 0.12
IGL02259:Atm APN 9 53,518,494 (GRCm38) splice site probably benign
IGL02351:Atm APN 9 53,522,176 (GRCm38) missense probably benign 0.04
IGL02358:Atm APN 9 53,522,176 (GRCm38) missense probably benign 0.04
IGL02387:Atm APN 9 53,479,766 (GRCm38) splice site probably null
IGL02417:Atm APN 9 53,479,695 (GRCm38) missense probably benign 0.00
IGL02422:Atm APN 9 53,500,792 (GRCm38) missense probably damaging 1.00
IGL02445:Atm APN 9 53,454,330 (GRCm38) missense probably benign 0.00
IGL02492:Atm APN 9 53,455,859 (GRCm38) missense probably damaging 0.99
IGL02513:Atm APN 9 53,497,262 (GRCm38) splice site probably benign
IGL02633:Atm APN 9 53,448,153 (GRCm38) missense probably damaging 1.00
IGL02634:Atm APN 9 53,516,563 (GRCm38) missense probably benign 0.00
IGL02948:Atm APN 9 53,453,440 (GRCm38) splice site probably benign
IGL02959:Atm APN 9 53,471,418 (GRCm38) missense probably damaging 1.00
IGL02965:Atm APN 9 53,453,563 (GRCm38) missense probably damaging 1.00
IGL03085:Atm APN 9 53,484,171 (GRCm38) missense possibly damaging 0.89
antebellum UTSW 9 53,518,559 (GRCm38) nonsense probably null
bull_run UTSW 9 53,487,922 (GRCm38) missense probably benign 0.09
Civil UTSW 9 53,492,268 (GRCm38) missense possibly damaging 0.78
gettysburg UTSW 9 53,455,988 (GRCm38) splice site probably null
Grant UTSW 9 53,511,917 (GRCm38) nonsense probably null
Indicative UTSW 9 53,445,376 (GRCm38) splice site probably null
Marker UTSW 9 53,454,279 (GRCm38) splice site probably benign
maunder UTSW 9 53,499,197 (GRCm38) nonsense probably null
mockingbird UTSW 9 53,516,467 (GRCm38) nonsense probably null
mockingbird2 UTSW 9 53,488,587 (GRCm38) missense probably damaging 1.00
osphere UTSW 9 53,479,673 (GRCm38) missense probably damaging 0.99
shiloh UTSW 9 53,465,298 (GRCm38) missense probably damaging 1.00
Strato UTSW 9 53,503,018 (GRCm38) missense probably damaging 1.00
thrasher UTSW 9 53,445,507 (GRCm38) missense probably benign 0.01
Tropo UTSW 9 53,531,648 (GRCm38) missense probably damaging 1.00
P0019:Atm UTSW 9 53,465,028 (GRCm38) splice site probably benign
PIT4403001:Atm UTSW 9 53,500,982 (GRCm38) missense probably benign
PIT4687001:Atm UTSW 9 53,486,812 (GRCm38) critical splice donor site probably null
R0004:Atm UTSW 9 53,453,528 (GRCm38) splice site probably benign
R0035:Atm UTSW 9 53,513,180 (GRCm38) missense probably benign 0.01
R0098:Atm UTSW 9 53,518,569 (GRCm38) missense probably benign 0.10
R0098:Atm UTSW 9 53,518,569 (GRCm38) missense probably benign 0.10
R0201:Atm UTSW 9 53,454,279 (GRCm38) splice site probably benign
R0304:Atm UTSW 9 53,516,344 (GRCm38) missense probably benign 0.34
R0308:Atm UTSW 9 53,454,473 (GRCm38) splice site probably null
R0362:Atm UTSW 9 53,458,838 (GRCm38) missense possibly damaging 0.90
R0470:Atm UTSW 9 53,460,966 (GRCm38) missense probably damaging 1.00
R0513:Atm UTSW 9 53,503,948 (GRCm38) missense probably benign 0.00
R0589:Atm UTSW 9 53,490,192 (GRCm38) missense possibly damaging 0.51
R0617:Atm UTSW 9 53,458,941 (GRCm38) nonsense probably null
R0630:Atm UTSW 9 53,531,622 (GRCm38) splice site probably benign
R0652:Atm UTSW 9 53,486,014 (GRCm38) missense probably damaging 0.98
R0698:Atm UTSW 9 53,515,239 (GRCm38) missense probably damaging 1.00
R0737:Atm UTSW 9 53,456,566 (GRCm38) missense probably damaging 1.00
R0885:Atm UTSW 9 53,459,823 (GRCm38) missense probably benign
R0947:Atm UTSW 9 53,504,092 (GRCm38) missense probably benign 0.01
R0948:Atm UTSW 9 53,495,958 (GRCm38) missense probably benign
R1144:Atm UTSW 9 53,511,698 (GRCm38) splice site probably benign
R1252:Atm UTSW 9 53,455,840 (GRCm38) missense probably damaging 1.00
R1295:Atm UTSW 9 53,456,530 (GRCm38) missense probably damaging 1.00
R1296:Atm UTSW 9 53,456,530 (GRCm38) missense probably damaging 1.00
R1419:Atm UTSW 9 53,457,489 (GRCm38) missense probably benign 0.00
R1477:Atm UTSW 9 53,464,273 (GRCm38) missense probably benign 0.00
R1596:Atm UTSW 9 53,453,378 (GRCm38) missense probably damaging 1.00
R1630:Atm UTSW 9 53,479,673 (GRCm38) missense probably damaging 0.99
R1667:Atm UTSW 9 53,500,932 (GRCm38) missense probably damaging 1.00
R1681:Atm UTSW 9 53,522,155 (GRCm38) missense possibly damaging 0.94
R1703:Atm UTSW 9 53,500,700 (GRCm38) missense probably benign
R1817:Atm UTSW 9 53,492,233 (GRCm38) splice site probably benign
R1840:Atm UTSW 9 53,456,530 (GRCm38) missense probably damaging 1.00
R1848:Atm UTSW 9 53,468,012 (GRCm38) missense probably benign 0.06
R1906:Atm UTSW 9 53,506,568 (GRCm38) missense probably damaging 1.00
R1958:Atm UTSW 9 53,471,418 (GRCm38) missense probably damaging 1.00
R2108:Atm UTSW 9 53,443,997 (GRCm38) missense probably damaging 1.00
R2116:Atm UTSW 9 53,500,969 (GRCm38) missense probably benign 0.36
R2134:Atm UTSW 9 53,467,964 (GRCm38) critical splice donor site probably null
R2137:Atm UTSW 9 53,453,375 (GRCm38) missense probably damaging 1.00
R2291:Atm UTSW 9 53,490,909 (GRCm38) splice site probably null
R2348:Atm UTSW 9 53,492,268 (GRCm38) missense possibly damaging 0.78
R2483:Atm UTSW 9 53,510,266 (GRCm38) missense probably damaging 1.00
R2567:Atm UTSW 9 53,457,470 (GRCm38) missense possibly damaging 0.72
R2897:Atm UTSW 9 53,507,805 (GRCm38) missense probably damaging 0.99
R2939:Atm UTSW 9 53,494,711 (GRCm38) missense probably damaging 1.00
R3008:Atm UTSW 9 53,480,750 (GRCm38) missense probably benign 0.00
R3236:Atm UTSW 9 53,479,748 (GRCm38) missense probably benign 0.15
R3847:Atm UTSW 9 53,503,075 (GRCm38) missense possibly damaging 0.94
R3889:Atm UTSW 9 53,506,636 (GRCm38) splice site probably benign
R3919:Atm UTSW 9 53,492,278 (GRCm38) missense probably benign 0.00
R4125:Atm UTSW 9 53,450,621 (GRCm38) missense probably damaging 1.00
R4222:Atm UTSW 9 53,480,669 (GRCm38) missense probably benign
R4395:Atm UTSW 9 53,465,227 (GRCm38) missense probably benign 0.09
R4466:Atm UTSW 9 53,448,169 (GRCm38) nonsense probably null
R4502:Atm UTSW 9 53,495,946 (GRCm38) missense possibly damaging 0.92
R4514:Atm UTSW 9 53,493,039 (GRCm38) missense probably damaging 0.99
R4528:Atm UTSW 9 53,500,759 (GRCm38) missense probably benign 0.39
R4593:Atm UTSW 9 53,453,594 (GRCm38) missense possibly damaging 0.55
R4627:Atm UTSW 9 53,456,506 (GRCm38) missense possibly damaging 0.79
R4634:Atm UTSW 9 53,531,733 (GRCm38) missense probably benign 0.01
R4665:Atm UTSW 9 53,464,229 (GRCm38) missense probably benign 0.00
R4672:Atm UTSW 9 53,522,201 (GRCm38) missense probably damaging 0.99
R4741:Atm UTSW 9 53,453,607 (GRCm38) missense probably benign 0.10
R4808:Atm UTSW 9 53,445,495 (GRCm38) missense probably damaging 0.99
R4959:Atm UTSW 9 53,515,301 (GRCm38) missense probably benign
R4996:Atm UTSW 9 53,524,507 (GRCm38) missense probably benign 0.09
R5030:Atm UTSW 9 53,520,109 (GRCm38) nonsense probably null
R5214:Atm UTSW 9 53,491,027 (GRCm38) missense probably benign 0.09
R5260:Atm UTSW 9 53,506,611 (GRCm38) missense probably damaging 0.99
R5311:Atm UTSW 9 53,518,623 (GRCm38) missense probably benign 0.00
R5394:Atm UTSW 9 53,507,777 (GRCm38) critical splice donor site probably null
R5400:Atm UTSW 9 53,503,018 (GRCm38) missense probably damaging 1.00
R5436:Atm UTSW 9 53,459,804 (GRCm38) missense probably benign 0.00
R5441:Atm UTSW 9 53,516,467 (GRCm38) nonsense probably null
R5569:Atm UTSW 9 53,516,450 (GRCm38) nonsense probably null
R5856:Atm UTSW 9 53,495,955 (GRCm38) missense possibly damaging 0.64
R5891:Atm UTSW 9 53,497,159 (GRCm38) missense probably benign
R5910:Atm UTSW 9 53,448,080 (GRCm38) missense probably damaging 0.96
R6054:Atm UTSW 9 53,459,873 (GRCm38) missense probably damaging 1.00
R6062:Atm UTSW 9 53,488,587 (GRCm38) missense probably damaging 1.00
R6092:Atm UTSW 9 53,524,414 (GRCm38) missense probably damaging 1.00
R6127:Atm UTSW 9 53,524,509 (GRCm38) missense probably damaging 1.00
R6160:Atm UTSW 9 53,490,959 (GRCm38) missense probably benign 0.04
R6267:Atm UTSW 9 53,444,000 (GRCm38) missense probably damaging 1.00
R6273:Atm UTSW 9 53,487,922 (GRCm38) missense probably benign 0.09
R6284:Atm UTSW 9 53,445,376 (GRCm38) splice site probably null
R6478:Atm UTSW 9 53,490,254 (GRCm38) missense probably damaging 1.00
R6547:Atm UTSW 9 53,440,157 (GRCm38) missense probably damaging 1.00
R6549:Atm UTSW 9 53,493,177 (GRCm38) missense probably benign 0.00
R6704:Atm UTSW 9 53,458,853 (GRCm38) missense probably benign 0.02
R6715:Atm UTSW 9 53,531,648 (GRCm38) missense probably damaging 1.00
R6737:Atm UTSW 9 53,486,051 (GRCm38) missense probably benign 0.30
R6759:Atm UTSW 9 53,518,559 (GRCm38) nonsense probably null
R6766:Atm UTSW 9 53,490,282 (GRCm38) missense probably damaging 0.99
R6813:Atm UTSW 9 53,497,235 (GRCm38) missense probably benign 0.00
R6852:Atm UTSW 9 53,482,430 (GRCm38) missense possibly damaging 0.93
R7064:Atm UTSW 9 53,507,881 (GRCm38) missense probably benign 0.02
R7208:Atm UTSW 9 53,512,008 (GRCm38) splice site probably null
R7211:Atm UTSW 9 53,488,560 (GRCm38) missense probably benign 0.01
R7220:Atm UTSW 9 53,511,917 (GRCm38) nonsense probably null
R7336:Atm UTSW 9 53,462,503 (GRCm38) missense possibly damaging 0.47
R7363:Atm UTSW 9 53,465,298 (GRCm38) missense probably damaging 1.00
R7378:Atm UTSW 9 53,453,437 (GRCm38) critical splice acceptor site probably null
R7472:Atm UTSW 9 53,448,125 (GRCm38) missense possibly damaging 0.81
R7487:Atm UTSW 9 53,524,354 (GRCm38) missense probably benign
R7497:Atm UTSW 9 53,511,891 (GRCm38) missense probably benign 0.00
R7584:Atm UTSW 9 53,513,127 (GRCm38) missense probably damaging 0.99
R7624:Atm UTSW 9 53,454,768 (GRCm38) missense probably damaging 0.99
R7653:Atm UTSW 9 53,490,302 (GRCm38) nonsense probably null
R7660:Atm UTSW 9 53,445,507 (GRCm38) missense probably benign 0.01
R7679:Atm UTSW 9 53,442,497 (GRCm38) missense probably damaging 1.00
R8221:Atm UTSW 9 53,455,988 (GRCm38) splice site probably null
R8247:Atm UTSW 9 53,450,570 (GRCm38) missense
R8334:Atm UTSW 9 53,522,273 (GRCm38) missense probably benign 0.00
R8503:Atm UTSW 9 53,488,052 (GRCm38) missense probably damaging 0.99
R8552:Atm UTSW 9 53,524,497 (GRCm38) missense probably damaging 1.00
R8749:Atm UTSW 9 53,499,197 (GRCm38) nonsense probably null
R8838:Atm UTSW 9 53,516,551 (GRCm38) missense probably damaging 0.99
R9126:Atm UTSW 9 53,458,834 (GRCm38) missense probably benign 0.01
R9131:Atm UTSW 9 53,533,744 (GRCm38) missense probably benign 0.10
R9191:Atm UTSW 9 53,527,290 (GRCm38) missense probably benign 0.29
R9257:Atm UTSW 9 53,495,850 (GRCm38) critical splice donor site probably null
R9473:Atm UTSW 9 53,498,972 (GRCm38) missense probably benign
R9558:Atm UTSW 9 53,500,781 (GRCm38) missense probably benign 0.00
R9598:Atm UTSW 9 53,520,081 (GRCm38) missense probably benign 0.34
R9717:Atm UTSW 9 53,516,517 (GRCm38) missense probably damaging 1.00
R9794:Atm UTSW 9 53,518,567 (GRCm38) missense probably benign
X0067:Atm UTSW 9 53,479,694 (GRCm38) missense probably benign 0.00
Z1088:Atm UTSW 9 53,531,687 (GRCm38) missense probably damaging 1.00
Predicted Primers PCR Primer
(F):5'- GCTCCTTGTGGATGATGGATATAAATC -3'
(R):5'- AGCCCCAAGTGAGAATCAGTG -3'

Sequencing Primer
(F):5'- TGTGGATGATGGATATAAATCTGCAG -3'
(R):5'- TTACACCCAGTTGACCCT -3'
Posted On 2019-11-12