Incidental Mutation 'R7727:Sgsm1'
| ID |
595552 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Sgsm1
|
| Ensembl Gene |
ENSMUSG00000042216 |
| Gene Name |
small G protein signaling modulator 1 |
| Synonyms |
Rutbc2, 2410098H20Rik, D5Bwg1524e |
| MMRRC Submission |
045783-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7727 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
113243220-113310786 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 113274327 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Lysine
at position 487
(M487K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000046544
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000048112]
[ENSMUST00000057209]
[ENSMUST00000112324]
[ENSMUST00000112325]
[ENSMUST00000154248]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000048112
AA Change: M487K
PolyPhen 2
Score 0.947 (Sensitivity: 0.79; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000046544
Gene: ENSMUSG00000042216
AA Change: M487K
| Domain | Start | End | E-Value | Type |
|---|
|
RUN
|
127 |
187 |
6.52e-18 |
SMART |
|
low complexity region
|
401 |
413 |
N/A |
INTRINSIC |
|
low complexity region
|
454 |
469 |
N/A |
INTRINSIC |
|
TBC
|
559 |
1053 |
2.88e-29 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000057209
AA Change: M200K
PolyPhen 2
Score 0.992 (Sensitivity: 0.70; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000084106
Gene: ENSMUSG00000042216
AA Change: M200K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
114 |
126 |
N/A |
INTRINSIC |
|
low complexity region
|
167 |
182 |
N/A |
INTRINSIC |
|
TBC
|
272 |
766 |
2.88e-29 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000112324
AA Change: M200K
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000107943
Gene: ENSMUSG00000042216
AA Change: M200K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
114 |
126 |
N/A |
INTRINSIC |
|
low complexity region
|
167 |
182 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000112325
AA Change: M487K
PolyPhen 2
Score 0.945 (Sensitivity: 0.80; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000107944
Gene: ENSMUSG00000042216
AA Change: M487K
| Domain | Start | End | E-Value | Type |
|---|
|
RUN
|
127 |
187 |
6.52e-18 |
SMART |
|
low complexity region
|
401 |
413 |
N/A |
INTRINSIC |
|
low complexity region
|
454 |
469 |
N/A |
INTRINSIC |
|
SCOP:d1fkma1
|
539 |
615 |
1e-6 |
SMART |
|
Blast:TBC
|
559 |
675 |
1e-71 |
BLAST |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000154248
AA Change: M542K
PolyPhen 2
Score 0.981 (Sensitivity: 0.75; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000114932
Gene: ENSMUSG00000042216
AA Change: M542K
| Domain | Start | End | E-Value | Type |
|---|
|
RUN
|
127 |
187 |
6.52e-18 |
SMART |
|
low complexity region
|
401 |
413 |
N/A |
INTRINSIC |
|
low complexity region
|
509 |
524 |
N/A |
INTRINSIC |
|
SCOP:d1fkma1
|
594 |
670 |
9e-7 |
SMART |
|
Blast:TBC
|
614 |
706 |
3e-55 |
BLAST |
|
| Meta Mutation Damage Score |
0.8472 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.9%
|
| Validation Efficiency |
100% (69/69) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 69 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adamts5 |
A |
T |
16: 85,899,966 (GRCm38) |
L101Q |
probably damaging |
Het |
| Arhgap18 |
A |
T |
10: 26,870,011 (GRCm38) |
I293F |
possibly damaging |
Het |
| Atp8b1 |
T |
A |
18: 64,545,275 (GRCm38) |
Q850L |
probably damaging |
Het |
| B4galnt3 |
A |
T |
6: 120,225,187 (GRCm38) |
F118Y |
probably benign |
Het |
| Bcl6 |
A |
G |
16: 23,971,413 (GRCm38) |
|
probably null |
Het |
| Cc2d2b |
T |
A |
19: 40,756,530 (GRCm38) |
L31Q |
probably benign |
Het |
| Cd5l |
G |
T |
3: 87,367,855 (GRCm38) |
E234* |
probably null |
Het |
| Cemip2 |
C |
T |
19: 21,829,957 (GRCm38) |
L917F |
probably benign |
Het |
| Cfap65 |
T |
C |
1: 74,926,625 (GRCm38) |
T409A |
probably benign |
Het |
| Chst5 |
A |
T |
8: 111,890,925 (GRCm38) |
I21N |
probably benign |
Het |
| Cldn20 |
T |
C |
17: 3,532,755 (GRCm38) |
Y68H |
probably benign |
Het |
| Col4a4 |
T |
C |
1: 82,528,793 (GRCm38) |
M269V |
unknown |
Het |
| Dgkh |
A |
G |
14: 78,595,145 (GRCm38) |
|
probably null |
Het |
| Dpp6 |
A |
G |
5: 27,451,244 (GRCm38) |
T166A |
probably benign |
Het |
| Drosha |
A |
G |
15: 12,881,645 (GRCm38) |
D754G |
probably damaging |
Het |
| Epb41l4a |
C |
A |
18: 33,854,273 (GRCm38) |
K350N |
probably damaging |
Het |
| Fsd1 |
T |
G |
17: 55,988,150 (GRCm38) |
D46E |
probably benign |
Het |
| Gabra1 |
T |
C |
11: 42,133,591 (GRCm38) |
D419G |
probably damaging |
Het |
| Golga4 |
T |
A |
9: 118,548,702 (GRCm38) |
D458E |
probably damaging |
Het |
| Grm6 |
C |
A |
11: 50,851,542 (GRCm38) |
A134E |
probably benign |
Het |
| Ikzf1 |
T |
A |
11: 11,748,339 (GRCm38) |
S63R |
probably damaging |
Het |
| Ilvbl |
G |
A |
10: 78,576,666 (GRCm38) |
V74I |
probably benign |
Het |
| Kcng2 |
C |
T |
18: 80,296,090 (GRCm38) |
V328M |
probably benign |
Het |
| Kpna7 |
T |
C |
5: 145,005,045 (GRCm38) |
E145G |
probably benign |
Het |
| Krt81 |
A |
G |
15: 101,459,567 (GRCm38) |
V428A |
probably damaging |
Het |
| Lalba |
T |
C |
15: 98,482,668 (GRCm38) |
M2V |
probably benign |
Het |
| Lrpprc |
T |
C |
17: 84,776,947 (GRCm38) |
S113G |
probably benign |
Het |
| Mboat1 |
A |
C |
13: 30,226,306 (GRCm38) |
M249L |
probably benign |
Het |
| Meltf |
T |
C |
16: 31,883,794 (GRCm38) |
V113A |
probably damaging |
Het |
| Muc16 |
T |
A |
9: 18,660,242 (GRCm38) |
H327L |
unknown |
Het |
| Myh1 |
A |
G |
11: 67,215,922 (GRCm38) |
I1277V |
probably benign |
Het |
| Naf1 |
GCTCGGATCCCGGCGGAAGACCACCGCCGCTGCCAGCCCCGAACTCGGATCCCGGCGGAAGACCACCGCCGCTGCCAGCCCCGAGCTCGGATCCCGGCGGAAGACCACCGCCGCTGCCAGCCCCGAACTCGGATCCCGGCGGAAGACCACCGCCGCTGCCAGCCCCGAGCTCGGATCCCGGCGGAAGACCACCGCCGCTGCCAGCCCCGAACTCGGATCCCGGCGGAAGACCACCGCCGCCGCCAGCCCCGAGCTCGGATCCCGGCGGAAGACCACCGCCGCCGCCAGCCCCGAACTGGGATGCGGGCGGAAGACCACCACCGCCGCCAGCCCCGAACTCGGATCCCGGCGGAAGACC |
GCTCGGATCCCGGCGGAAGACCACCGCCGCTGCCAGCCCCGAGCTCGGATCCCGGCGGAAGACCACCGCCGCTGCCAGCCCCGAACTCGGATCCCGGCGGAAGACCACCGCCGCTGCCAGCCCCGAGCTCGGATCCCGGCGGAAGACCACCGCCGCTGCCAGCCCCGAACTCGGATCCCGGCGGAAGACCACCGCCGCCGCCAGCCCCGAGCTCGGATCCCGGCGGAAGACCACCGCCGCCGCCAGCCCCGAACTGGGATGCGGGCGGAAGACCACCACCGCCGCCAGCCCCGAACTCGGATCCCGGCGGAAGACC |
8: 66,860,548 (GRCm38) |
|
probably benign |
Het |
| Naga |
C |
A |
15: 82,330,147 (GRCm38) |
V388L |
probably benign |
Het |
| Nfkb1 |
A |
C |
3: 135,585,401 (GRCm38) |
M957R |
possibly damaging |
Het |
| Nol12 |
C |
A |
15: 78,940,593 (GRCm38) |
S157* |
probably null |
Het |
| Or13c25 |
A |
G |
4: 52,911,368 (GRCm38) |
V142A |
possibly damaging |
Het |
| Or5g23 |
A |
G |
2: 85,608,407 (GRCm38) |
F168L |
possibly damaging |
Het |
| Or8u3-ps |
A |
T |
2: 86,122,496 (GRCm38) |
D191V |
possibly damaging |
Het |
| Pcdhga5 |
T |
C |
18: 37,695,045 (GRCm38) |
V182A |
probably benign |
Het |
| Pik3r4 |
A |
G |
9: 105,669,882 (GRCm38) |
E953G |
probably damaging |
Het |
| Piwil2 |
C |
T |
14: 70,394,057 (GRCm38) |
R646Q |
probably damaging |
Het |
| Plxnc1 |
T |
C |
10: 94,944,109 (GRCm38) |
H157R |
probably damaging |
Het |
| Prrg4 |
A |
T |
2: 104,839,378 (GRCm38) |
F131L |
probably benign |
Het |
| Prss3b |
C |
A |
6: 41,033,193 (GRCm38) |
R69L |
probably benign |
Het |
| Rab28 |
A |
G |
5: 41,707,970 (GRCm38) |
S4P |
probably damaging |
Het |
| Ranbp2 |
C |
A |
10: 58,455,438 (GRCm38) |
Q209K |
probably benign |
Het |
| Schip1 |
G |
A |
3: 68,064,984 (GRCm38) |
D15N |
probably benign |
Het |
| Serpina3f |
T |
G |
12: 104,218,218 (GRCm38) |
M207R |
probably benign |
Het |
| Sh3tc2 |
A |
T |
18: 61,989,580 (GRCm38) |
I471F |
probably benign |
Het |
| Slamf1 |
G |
A |
1: 171,774,899 (GRCm38) |
V65I |
possibly damaging |
Het |
| Slit3 |
T |
C |
11: 35,684,044 (GRCm38) |
C1062R |
probably damaging |
Het |
| Snapc4 |
T |
G |
2: 26,373,434 (GRCm38) |
K344N |
probably damaging |
Het |
| Sorl1 |
A |
G |
9: 41,984,526 (GRCm38) |
Y1778H |
probably damaging |
Het |
| Spon2 |
G |
A |
5: 33,215,675 (GRCm38) |
R228C |
probably damaging |
Het |
| Sv2c |
A |
G |
13: 95,976,695 (GRCm38) |
I582T |
possibly damaging |
Het |
| Tamm41 |
C |
T |
6: 115,016,178 (GRCm38) |
V205M |
probably damaging |
Het |
| Trpm2 |
T |
C |
10: 77,925,789 (GRCm38) |
D1009G |
probably benign |
Het |
| Trpm6 |
T |
C |
19: 18,854,249 (GRCm38) |
S1493P |
probably damaging |
Het |
| Ttc34 |
G |
A |
4: 154,839,274 (GRCm38) |
V147I |
possibly damaging |
Het |
| Tut7 |
A |
G |
13: 59,799,682 (GRCm38) |
F942L |
probably benign |
Het |
| Uba2 |
C |
T |
7: 34,150,850 (GRCm38) |
A393T |
probably damaging |
Het |
| Ubn2 |
T |
A |
6: 38,463,938 (GRCm38) |
N416K |
probably benign |
Het |
| Uevld |
T |
C |
7: 46,943,805 (GRCm38) |
N233S |
probably benign |
Het |
| Upp2 |
G |
A |
2: 58,774,148 (GRCm38) |
M142I |
possibly damaging |
Het |
| Vps52 |
T |
A |
17: 33,962,134 (GRCm38) |
V450D |
probably benign |
Het |
| Wdr31 |
A |
T |
4: 62,460,636 (GRCm38) |
F118Y |
probably damaging |
Het |
| Zfp110 |
T |
A |
7: 12,848,995 (GRCm38) |
D523E |
possibly damaging |
Het |
| Zfp367 |
A |
T |
13: 64,145,643 (GRCm38) |
V143D |
probably damaging |
Het |
| Zfp950 |
T |
C |
19: 61,119,941 (GRCm38) |
I235V |
probably benign |
Het |
|
| Other mutations in Sgsm1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00230:Sgsm1
|
APN |
5 |
113,245,064 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL00503:Sgsm1
|
APN |
5 |
113,276,142 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01377:Sgsm1
|
APN |
5 |
113,276,182 (GRCm38) |
splice site |
probably benign |
|
|
IGL01602:Sgsm1
|
APN |
5 |
113,285,665 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
IGL01605:Sgsm1
|
APN |
5 |
113,285,665 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
IGL01669:Sgsm1
|
APN |
5 |
113,263,490 (GRCm38) |
missense |
probably benign |
|
|
IGL01920:Sgsm1
|
APN |
5 |
113,273,605 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01951:Sgsm1
|
APN |
5 |
113,286,767 (GRCm38) |
splice site |
probably benign |
|
|
IGL02387:Sgsm1
|
APN |
5 |
113,253,063 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
IGL02690:Sgsm1
|
APN |
5 |
113,286,767 (GRCm38) |
splice site |
probably benign |
|
|
IGL03177:Sgsm1
|
APN |
5 |
113,250,993 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03186:Sgsm1
|
APN |
5 |
113,285,021 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL03398:Sgsm1
|
APN |
5 |
113,255,316 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
caliente
|
UTSW |
5 |
113,280,462 (GRCm38) |
intron |
probably benign |
|
|
Chili
|
UTSW |
5 |
113,258,123 (GRCm38) |
intron |
probably benign |
|
|
pimiento
|
UTSW |
5 |
113,263,257 (GRCm38) |
missense |
probably benign |
0.15 |
|
R0048:Sgsm1
|
UTSW |
5 |
113,268,750 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0058:Sgsm1
|
UTSW |
5 |
113,285,087 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0058:Sgsm1
|
UTSW |
5 |
113,285,087 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0082:Sgsm1
|
UTSW |
5 |
113,288,836 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0085:Sgsm1
|
UTSW |
5 |
113,279,270 (GRCm38) |
splice site |
probably benign |
|
|
R0099:Sgsm1
|
UTSW |
5 |
113,274,360 (GRCm38) |
splice site |
probably benign |
|
|
R0269:Sgsm1
|
UTSW |
5 |
113,286,929 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R0310:Sgsm1
|
UTSW |
5 |
113,263,705 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0325:Sgsm1
|
UTSW |
5 |
113,288,835 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0420:Sgsm1
|
UTSW |
5 |
113,263,759 (GRCm38) |
missense |
probably benign |
0.16 |
|
R0594:Sgsm1
|
UTSW |
5 |
113,310,562 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0599:Sgsm1
|
UTSW |
5 |
113,245,028 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0631:Sgsm1
|
UTSW |
5 |
113,285,123 (GRCm38) |
splice site |
probably benign |
|
|
R0744:Sgsm1
|
UTSW |
5 |
113,279,184 (GRCm38) |
missense |
probably benign |
0.38 |
|
R0833:Sgsm1
|
UTSW |
5 |
113,279,184 (GRCm38) |
missense |
probably benign |
0.38 |
|
R0919:Sgsm1
|
UTSW |
5 |
113,258,842 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0944:Sgsm1
|
UTSW |
5 |
113,265,874 (GRCm38) |
missense |
probably benign |
0.40 |
|
R1169:Sgsm1
|
UTSW |
5 |
113,279,485 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1232:Sgsm1
|
UTSW |
5 |
113,273,711 (GRCm38) |
nonsense |
probably null |
|
|
R1473:Sgsm1
|
UTSW |
5 |
113,263,257 (GRCm38) |
missense |
probably benign |
0.15 |
|
R1535:Sgsm1
|
UTSW |
5 |
113,263,269 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R1796:Sgsm1
|
UTSW |
5 |
113,273,617 (GRCm38) |
missense |
possibly damaging |
0.58 |
|
R1878:Sgsm1
|
UTSW |
5 |
113,263,515 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R2084:Sgsm1
|
UTSW |
5 |
113,285,400 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3855:Sgsm1
|
UTSW |
5 |
113,263,259 (GRCm38) |
missense |
probably benign |
0.01 |
|
R3856:Sgsm1
|
UTSW |
5 |
113,263,259 (GRCm38) |
missense |
probably benign |
0.01 |
|
R4294:Sgsm1
|
UTSW |
5 |
113,285,404 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4373:Sgsm1
|
UTSW |
5 |
113,258,123 (GRCm38) |
intron |
probably benign |
|
|
R4558:Sgsm1
|
UTSW |
5 |
113,258,111 (GRCm38) |
intron |
probably benign |
|
|
R4610:Sgsm1
|
UTSW |
5 |
113,255,307 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4667:Sgsm1
|
UTSW |
5 |
113,260,047 (GRCm38) |
critical splice donor site |
probably null |
|
|
R4838:Sgsm1
|
UTSW |
5 |
113,282,626 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4890:Sgsm1
|
UTSW |
5 |
113,280,462 (GRCm38) |
intron |
probably benign |
|
|
R4992:Sgsm1
|
UTSW |
5 |
113,282,620 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R5366:Sgsm1
|
UTSW |
5 |
113,251,039 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R5776:Sgsm1
|
UTSW |
5 |
113,250,957 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5813:Sgsm1
|
UTSW |
5 |
113,250,956 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6000:Sgsm1
|
UTSW |
5 |
113,286,838 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6354:Sgsm1
|
UTSW |
5 |
113,282,656 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R6440:Sgsm1
|
UTSW |
5 |
113,279,131 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6831:Sgsm1
|
UTSW |
5 |
113,280,380 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R7307:Sgsm1
|
UTSW |
5 |
113,273,646 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7309:Sgsm1
|
UTSW |
5 |
113,268,846 (GRCm38) |
splice site |
probably null |
|
|
R7387:Sgsm1
|
UTSW |
5 |
113,263,700 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7439:Sgsm1
|
UTSW |
5 |
113,274,321 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7485:Sgsm1
|
UTSW |
5 |
113,279,635 (GRCm38) |
splice site |
probably null |
|
|
R7624:Sgsm1
|
UTSW |
5 |
113,274,335 (GRCm38) |
nonsense |
probably null |
|
|
R7632:Sgsm1
|
UTSW |
5 |
113,276,082 (GRCm38) |
missense |
possibly damaging |
0.54 |
|
R7669:Sgsm1
|
UTSW |
5 |
113,253,024 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7732:Sgsm1
|
UTSW |
5 |
113,266,330 (GRCm38) |
missense |
probably benign |
0.26 |
|
R7961:Sgsm1
|
UTSW |
5 |
113,282,644 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8088:Sgsm1
|
UTSW |
5 |
113,255,268 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8213:Sgsm1
|
UTSW |
5 |
113,251,011 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8278:Sgsm1
|
UTSW |
5 |
113,260,092 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R8480:Sgsm1
|
UTSW |
5 |
113,263,418 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8796:Sgsm1
|
UTSW |
5 |
113,263,257 (GRCm38) |
missense |
probably benign |
0.15 |
|
R8816:Sgsm1
|
UTSW |
5 |
113,287,231 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8904:Sgsm1
|
UTSW |
5 |
113,273,629 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8905:Sgsm1
|
UTSW |
5 |
113,273,629 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8952:Sgsm1
|
UTSW |
5 |
113,284,995 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9046:Sgsm1
|
UTSW |
5 |
113,288,859 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9162:Sgsm1
|
UTSW |
5 |
113,282,711 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9249:Sgsm1
|
UTSW |
5 |
113,280,335 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R9375:Sgsm1
|
UTSW |
5 |
113,274,273 (GRCm38) |
missense |
unknown |
|
|
R9377:Sgsm1
|
UTSW |
5 |
113,288,875 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9461:Sgsm1
|
UTSW |
5 |
113,276,032 (GRCm38) |
critical splice donor site |
probably null |
|
|
R9662:Sgsm1
|
UTSW |
5 |
113,279,231 (GRCm38) |
missense |
probably benign |
0.03 |
|
R9722:Sgsm1
|
UTSW |
5 |
113,280,341 (GRCm38) |
missense |
possibly damaging |
0.75 |
|
R9726:Sgsm1
|
UTSW |
5 |
113,310,552 (GRCm38) |
missense |
probably benign |
|
|
Z1177:Sgsm1
|
UTSW |
5 |
113,282,710 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGCTAGTCCTGTCCCCTCAAAG -3'
(R):5'- CACAACGCTATGAATGGCTGATC -3'
Sequencing Primer
(F):5'- TCCTGTCCCCTCAAAGGAGTG -3'
(R):5'- CCAACAGAAACCTGGGCTGTG -3'
|
| Posted On |
2019-11-12 |
Incidental Mutation