Incidental Mutation 'R7729:St18'
| ID |
595672 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
St18
|
| Ensembl Gene |
ENSMUSG00000033740 |
| Gene Name |
suppression of tumorigenicity 18 |
| Synonyms |
Nzf3, Myt3 |
| MMRRC Submission |
045785-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7729 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
6487231-6860940 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 6802537 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Histidine to Glutamine
at position 165
(H165Q)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000042056
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000043578]
[ENSMUST00000131494]
[ENSMUST00000139838]
[ENSMUST00000140079]
[ENSMUST00000150761]
[ENSMUST00000151281]
[ENSMUST00000163727]
|
| AlphaFold |
Q80TY4 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000043578
AA Change: H165Q
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000042056
Gene: ENSMUSG00000033740
AA Change: H165Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
365 |
392 |
7.8e-15 |
PFAM |
|
Pfam:zf-C2HC
|
409 |
437 |
4.2e-17 |
PFAM |
|
Pfam:MYT1
|
476 |
713 |
1.3e-75 |
PFAM |
|
Pfam:zf-C2HC
|
721 |
749 |
4e-19 |
PFAM |
|
Pfam:zf-C2HC
|
765 |
793 |
1.7e-19 |
PFAM |
|
Pfam:zf-C2HC
|
813 |
841 |
1.1e-17 |
PFAM |
|
Pfam:zf-C2HC
|
866 |
893 |
9.1e-15 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000131494
AA Change: H165Q
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000117789
Gene: ENSMUSG00000033740
AA Change: H165Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
363 |
393 |
2.6e-17 |
PFAM |
|
Pfam:zf-C2HC
|
407 |
437 |
1e-18 |
PFAM |
|
Pfam:MYT1
|
476 |
714 |
1.5e-116 |
PFAM |
|
Pfam:zf-C2HC
|
719 |
749 |
1e-19 |
PFAM |
|
Pfam:zf-C2HC
|
763 |
793 |
1.3e-20 |
PFAM |
|
Pfam:zf-C2HC
|
811 |
841 |
8.9e-19 |
PFAM |
|
Pfam:zf-C2HC
|
864 |
894 |
1.3e-16 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000132207
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000139838
AA Change: H165Q
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000118129
Gene: ENSMUSG00000033740
AA Change: H165Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000140079
AA Change: H165Q
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000118322
Gene: ENSMUSG00000033740
AA Change: H165Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
363 |
393 |
2.6e-17 |
PFAM |
|
Pfam:zf-C2HC
|
407 |
437 |
1e-18 |
PFAM |
|
Pfam:MYT1
|
476 |
714 |
1.5e-116 |
PFAM |
|
Pfam:zf-C2HC
|
719 |
749 |
1e-19 |
PFAM |
|
Pfam:zf-C2HC
|
763 |
793 |
1.3e-20 |
PFAM |
|
Pfam:zf-C2HC
|
811 |
841 |
8.9e-19 |
PFAM |
|
Pfam:zf-C2HC
|
864 |
894 |
1.3e-16 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000150761
AA Change: H165Q
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000120298
Gene: ENSMUSG00000033740
AA Change: H165Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
363 |
393 |
2.6e-17 |
PFAM |
|
Pfam:zf-C2HC
|
407 |
437 |
1e-18 |
PFAM |
|
Pfam:MYT1
|
476 |
714 |
1.5e-116 |
PFAM |
|
Pfam:zf-C2HC
|
719 |
749 |
1e-19 |
PFAM |
|
Pfam:zf-C2HC
|
763 |
793 |
1.3e-20 |
PFAM |
|
Pfam:zf-C2HC
|
811 |
841 |
8.9e-19 |
PFAM |
|
Pfam:zf-C2HC
|
864 |
894 |
1.3e-16 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000151281
AA Change: H165Q
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000122055
Gene: ENSMUSG00000033740
AA Change: H165Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
363 |
393 |
2.6e-17 |
PFAM |
|
Pfam:zf-C2HC
|
407 |
437 |
1e-18 |
PFAM |
|
Pfam:MYT1
|
476 |
714 |
1.5e-116 |
PFAM |
|
Pfam:zf-C2HC
|
719 |
749 |
1e-19 |
PFAM |
|
Pfam:zf-C2HC
|
763 |
793 |
1.3e-20 |
PFAM |
|
Pfam:zf-C2HC
|
811 |
841 |
8.9e-19 |
PFAM |
|
Pfam:zf-C2HC
|
864 |
894 |
1.3e-16 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000163727
AA Change: H165Q
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000131417
Gene: ENSMUSG00000033740
AA Change: H165Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
365 |
392 |
7.8e-15 |
PFAM |
|
Pfam:zf-C2HC
|
409 |
437 |
4.2e-17 |
PFAM |
|
Pfam:MYT1
|
476 |
713 |
1.3e-75 |
PFAM |
|
Pfam:zf-C2HC
|
721 |
749 |
4e-19 |
PFAM |
|
Pfam:zf-C2HC
|
765 |
793 |
1.7e-19 |
PFAM |
|
Pfam:zf-C2HC
|
813 |
841 |
1.1e-17 |
PFAM |
|
Pfam:zf-C2HC
|
866 |
893 |
9.1e-15 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.7%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 72 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700014D04Rik |
C |
T |
13: 59,741,623 (GRCm38) |
M794I |
not run |
Het |
| 1810024B03Rik |
T |
G |
2: 127,186,790 (GRCm38) |
D163A |
possibly damaging |
Het |
| Abce1 |
A |
T |
8: 79,687,908 (GRCm38) |
I454N |
probably damaging |
Het |
| Acaca |
A |
G |
11: 84,371,513 (GRCm38) |
I1980M |
probably damaging |
Het |
| Adgrb2 |
C |
T |
4: 129,992,124 (GRCm38) |
T19M |
probably benign |
Het |
| Agmo |
T |
A |
12: 37,414,975 (GRCm38) |
S417T |
probably benign |
Het |
| Akap8l |
T |
C |
17: 32,333,094 (GRCm38) |
E403G |
probably damaging |
Het |
| Art5 |
C |
T |
7: 102,098,504 (GRCm38) |
A23T |
possibly damaging |
Het |
| Atg9a |
T |
C |
1: 75,184,560 (GRCm38) |
T681A |
probably benign |
Het |
| Atp11b |
A |
G |
3: 35,778,107 (GRCm38) |
Q37R |
probably damaging |
Het |
| Atp2a2 |
T |
C |
5: 122,491,766 (GRCm38) |
E80G |
probably benign |
Het |
| AW551984 |
G |
A |
9: 39,599,775 (GRCm38) |
P172L |
possibly damaging |
Het |
| Bace1 |
C |
T |
9: 45,858,445 (GRCm38) |
R296C |
probably damaging |
Het |
| Ccser1 |
T |
A |
6: 61,311,856 (GRCm38) |
H334Q |
probably benign |
Het |
| Chtf18 |
C |
T |
17: 25,723,517 (GRCm38) |
R449H |
probably damaging |
Het |
| Cit |
A |
G |
5: 115,984,822 (GRCm38) |
H1384R |
possibly damaging |
Het |
| Cltc |
A |
G |
11: 86,721,648 (GRCm38) |
I524T |
probably benign |
Het |
| Dctn1 |
T |
A |
6: 83,183,060 (GRCm38) |
I94N |
probably damaging |
Het |
| Ddx58 |
T |
A |
4: 40,206,034 (GRCm38) |
I853F |
possibly damaging |
Het |
| Dnhd1 |
A |
T |
7: 105,705,265 (GRCm38) |
D3078V |
probably damaging |
Het |
| Dock7 |
G |
A |
4: 99,055,446 (GRCm38) |
P520S |
|
Het |
| Epb41l4a |
C |
A |
18: 33,854,273 (GRCm38) |
K350N |
probably damaging |
Het |
| Eprs |
T |
A |
1: 185,413,169 (GRCm38) |
Y1130N |
probably damaging |
Het |
| Fcgrt |
T |
C |
7: 45,095,373 (GRCm38) |
T224A |
probably damaging |
Het |
| Flt1 |
T |
A |
5: 147,700,367 (GRCm38) |
T39S |
probably benign |
Het |
| Fxyd1 |
T |
C |
7: 31,053,471 (GRCm38) |
Y33C |
probably damaging |
Het |
| Gab2 |
T |
A |
7: 97,301,426 (GRCm38) |
V442E |
probably damaging |
Het |
| Ganab |
A |
G |
19: 8,914,712 (GRCm38) |
D800G |
probably benign |
Het |
| Gata4 |
C |
A |
14: 63,240,737 (GRCm38) |
A138S |
probably benign |
Het |
| Golga4 |
A |
G |
9: 118,556,063 (GRCm38) |
H751R |
possibly damaging |
Het |
| Hist1h1t |
A |
G |
13: 23,696,472 (GRCm38) |
R203G |
possibly damaging |
Het |
| Htra4 |
A |
G |
8: 25,037,077 (GRCm38) |
V234A |
possibly damaging |
Het |
| Igkv4-74 |
A |
T |
6: 69,184,970 (GRCm38) |
Y72N |
probably damaging |
Het |
| Iqsec3 |
T |
C |
6: 121,383,981 (GRCm38) |
K973E |
probably damaging |
Het |
| Khdc1b |
C |
A |
1: 21,384,841 (GRCm38) |
T108K |
probably benign |
Het |
| Krtap5-1 |
ACAGGGCTTGCAGCAGCTGGACTGACAGCAGCAGGGCTTGCAGCAGCTGGACTGACAGCAGCAGGGCTTGCAGCAGCTGGACTGACAGCAG |
ACAGGGCTTGCAGCAGCTGGACTGACAGCAGCAGGGCTTGCAGCAGCTGGACTGACAGCAG |
7: 142,296,596 (GRCm38) |
|
probably benign |
Het |
| Kyat3 |
A |
G |
3: 142,726,305 (GRCm38) |
|
probably null |
Het |
| Lrba |
T |
A |
3: 86,318,167 (GRCm38) |
V666E |
probably damaging |
Het |
| Mettl25 |
T |
A |
10: 105,766,010 (GRCm38) |
Y528F |
probably benign |
Het |
| Mms19 |
A |
T |
19: 41,952,465 (GRCm38) |
Y619* |
probably null |
Het |
| Nlrp12 |
A |
C |
7: 3,228,388 (GRCm38) |
|
probably null |
Het |
| Nol10 |
C |
T |
12: 17,424,675 (GRCm38) |
L623F |
possibly damaging |
Het |
| Oas1g |
A |
G |
5: 120,886,000 (GRCm38) |
F82S |
probably damaging |
Het |
| Olfr1537 |
G |
A |
9: 39,238,250 (GRCm38) |
P58L |
probably benign |
Het |
| Olfr195 |
C |
T |
16: 59,149,207 (GRCm38) |
A119V |
probably damaging |
Het |
| Olfr335-ps |
T |
G |
2: 36,301,760 (GRCm38) |
S74A |
probably benign |
Het |
| Oxr1 |
G |
A |
15: 41,823,467 (GRCm38) |
E582K |
probably damaging |
Het |
| Pdia3 |
A |
G |
2: 121,432,357 (GRCm38) |
D268G |
possibly damaging |
Het |
| Pramef12 |
T |
C |
4: 144,392,864 (GRCm38) |
S378G |
probably damaging |
Het |
| Rcor3 |
A |
G |
1: 192,101,778 (GRCm38) |
Y387H |
probably damaging |
Het |
| Rsf1 |
CGGCGGCGG |
CGGCGGCGGGGGCGGCGG |
7: 97,579,911 (GRCm38) |
|
probably benign |
Het |
| Rsl1 |
T |
C |
13: 67,182,220 (GRCm38) |
L244P |
possibly damaging |
Het |
| Scn5a |
G |
T |
9: 119,495,540 (GRCm38) |
N1407K |
probably damaging |
Het |
| Sdcbp |
C |
T |
4: 6,378,985 (GRCm38) |
A24V |
probably benign |
Het |
| Slc22a8 |
A |
G |
19: 8,593,959 (GRCm38) |
Y18C |
possibly damaging |
Het |
| Slc35d1 |
C |
T |
4: 103,214,847 (GRCm38) |
R7H |
probably damaging |
Het |
| Slco6d1 |
A |
T |
1: 98,497,523 (GRCm38) |
T599S |
probably damaging |
Het |
| Sub1 |
C |
T |
15: 11,986,503 (GRCm38) |
R86K |
probably damaging |
Het |
| Tectb |
G |
A |
19: 55,192,672 (GRCm38) |
V148M |
|
Het |
| Tgfb2 |
C |
A |
1: 186,630,757 (GRCm38) |
G290V |
possibly damaging |
Het |
| Tgm7 |
T |
C |
2: 121,093,710 (GRCm38) |
H577R |
probably benign |
Het |
| Tle2 |
T |
C |
10: 81,587,147 (GRCm38) |
S460P |
probably damaging |
Het |
| Tmem221 |
C |
A |
8: 71,558,802 (GRCm38) |
R3L |
possibly damaging |
Het |
| Tnfrsf19 |
C |
A |
14: 60,974,734 (GRCm38) |
V156L |
possibly damaging |
Het |
| Trav6-5 |
A |
G |
14: 53,491,507 (GRCm38) |
K75E |
probably benign |
Het |
| Trip10 |
G |
A |
17: 57,262,442 (GRCm38) |
G488S |
probably damaging |
Het |
| Usp34 |
A |
C |
11: 23,449,268 (GRCm38) |
K2419T |
|
Het |
| Vps13d |
T |
C |
4: 145,075,052 (GRCm38) |
Q3532R |
|
Het |
| Vps4a |
A |
T |
8: 107,040,897 (GRCm38) |
I163L |
probably damaging |
Het |
| Wrn |
T |
C |
8: 33,324,426 (GRCm38) |
H330R |
probably benign |
Het |
| Xpr1 |
T |
C |
1: 155,312,872 (GRCm38) |
I341V |
probably benign |
Het |
| Zfyve9 |
T |
C |
4: 108,691,776 (GRCm38) |
E105G |
probably benign |
Het |
|
| Other mutations in St18 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00089:St18
|
APN |
1 |
6,802,572 (GRCm38) |
missense |
probably benign |
0.07 |
|
IGL00840:St18
|
APN |
1 |
6,833,594 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01016:St18
|
APN |
1 |
6,844,323 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL01116:St18
|
APN |
1 |
6,802,632 (GRCm38) |
missense |
probably damaging |
0.96 |
|
IGL01719:St18
|
APN |
1 |
6,845,796 (GRCm38) |
splice site |
probably benign |
|
|
IGL01885:St18
|
APN |
1 |
6,844,372 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL02486:St18
|
APN |
1 |
6,820,083 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02611:St18
|
APN |
1 |
6,768,890 (GRCm38) |
splice site |
probably benign |
|
|
IGL02742:St18
|
APN |
1 |
6,802,316 (GRCm38) |
splice site |
probably benign |
|
|
IGL02953:St18
|
APN |
1 |
6,844,113 (GRCm38) |
splice site |
probably benign |
|
|
IGL02999:St18
|
APN |
1 |
6,817,605 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL03092:St18
|
APN |
1 |
6,768,894 (GRCm38) |
splice site |
probably benign |
|
|
Smallish
|
UTSW |
1 |
6,855,473 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL03055:St18
|
UTSW |
1 |
6,802,735 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0089:St18
|
UTSW |
1 |
6,848,948 (GRCm38) |
missense |
probably benign |
0.02 |
|
R0257:St18
|
UTSW |
1 |
6,819,962 (GRCm38) |
missense |
probably benign |
0.04 |
|
R0383:St18
|
UTSW |
1 |
6,803,024 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0588:St18
|
UTSW |
1 |
6,817,738 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0989:St18
|
UTSW |
1 |
6,827,881 (GRCm38) |
missense |
probably benign |
0.04 |
|
R1068:St18
|
UTSW |
1 |
6,795,562 (GRCm38) |
missense |
probably benign |
0.01 |
|
R1311:St18
|
UTSW |
1 |
6,845,644 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1530:St18
|
UTSW |
1 |
6,845,569 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R1723:St18
|
UTSW |
1 |
6,810,685 (GRCm38) |
splice site |
probably benign |
|
|
R1926:St18
|
UTSW |
1 |
6,802,689 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1927:St18
|
UTSW |
1 |
6,802,712 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2035:St18
|
UTSW |
1 |
6,802,328 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2091:St18
|
UTSW |
1 |
6,827,971 (GRCm38) |
missense |
probably benign |
0.08 |
|
R2139:St18
|
UTSW |
1 |
6,810,615 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R2261:St18
|
UTSW |
1 |
6,845,572 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R2300:St18
|
UTSW |
1 |
6,855,402 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2322:St18
|
UTSW |
1 |
6,844,124 (GRCm38) |
nonsense |
probably null |
|
|
R2846:St18
|
UTSW |
1 |
6,845,587 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R3738:St18
|
UTSW |
1 |
6,855,473 (GRCm38) |
critical splice donor site |
probably null |
|
|
R3739:St18
|
UTSW |
1 |
6,855,473 (GRCm38) |
critical splice donor site |
probably null |
|
|
R3772:St18
|
UTSW |
1 |
6,844,329 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3805:St18
|
UTSW |
1 |
6,802,353 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3953:St18
|
UTSW |
1 |
6,802,893 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4034:St18
|
UTSW |
1 |
6,855,473 (GRCm38) |
critical splice donor site |
probably null |
|
|
R4036:St18
|
UTSW |
1 |
6,827,786 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4407:St18
|
UTSW |
1 |
6,827,837 (GRCm38) |
missense |
probably benign |
0.29 |
|
R4527:St18
|
UTSW |
1 |
6,855,423 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4740:St18
|
UTSW |
1 |
6,817,604 (GRCm38) |
missense |
probably benign |
|
|
R4838:St18
|
UTSW |
1 |
6,802,905 (GRCm38) |
missense |
probably benign |
0.01 |
|
R5182:St18
|
UTSW |
1 |
6,817,653 (GRCm38) |
missense |
probably benign |
0.03 |
|
R5186:St18
|
UTSW |
1 |
6,802,317 (GRCm38) |
splice site |
probably null |
|
|
R5354:St18
|
UTSW |
1 |
6,844,171 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5423:St18
|
UTSW |
1 |
6,802,616 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R5724:St18
|
UTSW |
1 |
6,770,950 (GRCm38) |
missense |
probably benign |
0.13 |
|
R6182:St18
|
UTSW |
1 |
6,844,118 (GRCm38) |
splice site |
probably null |
|
|
R6491:St18
|
UTSW |
1 |
6,827,985 (GRCm38) |
nonsense |
probably null |
|
|
R6503:St18
|
UTSW |
1 |
6,795,397 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7037:St18
|
UTSW |
1 |
6,803,036 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R7098:St18
|
UTSW |
1 |
6,827,842 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7132:St18
|
UTSW |
1 |
6,859,127 (GRCm38) |
missense |
|
|
|
R7144:St18
|
UTSW |
1 |
6,833,594 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7150:St18
|
UTSW |
1 |
6,803,019 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7334:St18
|
UTSW |
1 |
6,802,559 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7502:St18
|
UTSW |
1 |
6,827,970 (GRCm38) |
missense |
probably benign |
0.09 |
|
R7848:St18
|
UTSW |
1 |
6,857,445 (GRCm38) |
critical splice donor site |
probably null |
|
|
R8088:St18
|
UTSW |
1 |
6,828,005 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8299:St18
|
UTSW |
1 |
6,802,992 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8338:St18
|
UTSW |
1 |
6,809,292 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8690:St18
|
UTSW |
1 |
6,802,564 (GRCm38) |
missense |
probably benign |
|
|
R8753:St18
|
UTSW |
1 |
6,845,791 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8808:St18
|
UTSW |
1 |
6,810,602 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8880:St18
|
UTSW |
1 |
6,795,395 (GRCm38) |
nonsense |
probably null |
|
|
R9055:St18
|
UTSW |
1 |
6,802,982 (GRCm38) |
nonsense |
probably null |
|
|
R9292:St18
|
UTSW |
1 |
6,827,882 (GRCm38) |
missense |
probably benign |
0.32 |
|
R9322:St18
|
UTSW |
1 |
6,795,523 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9530:St18
|
UTSW |
1 |
6,802,773 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9603:St18
|
UTSW |
1 |
6,845,587 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9611:St18
|
UTSW |
1 |
6,802,923 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9639:St18
|
UTSW |
1 |
6,859,022 (GRCm38) |
missense |
|
|
|
R9644:St18
|
UTSW |
1 |
6,859,052 (GRCm38) |
missense |
|
|
|
R9740:St18
|
UTSW |
1 |
6,803,063 (GRCm38) |
nonsense |
probably null |
|
|
R9750:St18
|
UTSW |
1 |
6,802,992 (GRCm38) |
missense |
probably benign |
0.01 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTACCTGCACAAGACAGCTC -3'
(R):5'- CACCTGTTCTCACAAGGGATAAAC -3'
Sequencing Primer
(F):5'- GACAGCTCACTCCAGAAGAAAG -3'
(R):5'- TTATCTCAGGAACTTCCAACAGGTC -3'
|
| Posted On |
2019-11-12 |
Incidental Mutation