Mutagenetix > Incidental Mutation

Incidental Mutation 'R7729:Usp34'

595723

Institutional Source

Beutler Lab

Gene Symbol

Usp34

Ensembl Gene

ENSMUSG00000056342

Gene Name

ubiquitin specific peptidase 34

Synonyms

Murr2, A530081C03Rik

MMRRC Submission

045785-MU

Accession Numbers

Essential gene?

Probably essential (E-score: 0.803) question?

Stock #

R7729 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

23256895-23440560 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to C at 23399268 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Lysine to Threonine at position 2419 (K2419T)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000130131] [ENSMUST00000180046]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000130131
AA Change: K641T

PolyPhen 2 Score 0.673 (Sensitivity: 0.86; Specificity: 0.92)

SMART Domains

Protein: ENSMUSP00000115168
Gene: ENSMUSG00000056342
AA Change: K641T

Domain	Start	End	E-Value	Type
low complexity region	33	45	N/A	INTRINSIC
Pfam:UCH	171	514	1.1e-48	PFAM
Pfam:UCH_1	172	470	1.6e-25	PFAM
low complexity region	763	785	N/A	INTRINSIC

Predicted Effect

SMART Domains

Protein: ENSMUSP00000120747
Gene: ENSMUSG00000056342
AA Change: K2419T

Domain	Start	End	E-Value	Type
low complexity region	489	500	N/A	INTRINSIC
low complexity region	530	544	N/A	INTRINSIC
low complexity region	591	610	N/A	INTRINSIC
coiled coil region	626	671	N/A	INTRINSIC
low complexity region	827	842	N/A	INTRINSIC
low complexity region	1207	1218	N/A	INTRINSIC
low complexity region	1399	1410	N/A	INTRINSIC
low complexity region	1518	1532	N/A	INTRINSIC
low complexity region	1751	1764	N/A	INTRINSIC
low complexity region	1812	1824	N/A	INTRINSIC
Pfam:UCH	1950	2293	7.6e-44	PFAM
Pfam:UCH_1	1951	2249	3.6e-22	PFAM
low complexity region	2542	2564	N/A	INTRINSIC
low complexity region	2672	2679	N/A	INTRINSIC
Blast:Drf_GBD	2943	3116	3e-53	BLAST
low complexity region	3344	3357	N/A	INTRINSIC
coiled coil region	3371	3393	N/A	INTRINSIC

Predicted Effect

possibly damaging
Transcript: ENSMUST00000180046
AA Change: K2400T

PolyPhen 2 Score 0.673 (Sensitivity: 0.86; Specificity: 0.92)

SMART Domains

Protein: ENSMUSP00000137430
Gene: ENSMUSG00000056342
AA Change: K2400T

Domain	Start	End	E-Value	Type
low complexity region	469	480	N/A	INTRINSIC
low complexity region	510	524	N/A	INTRINSIC
low complexity region	571	590	N/A	INTRINSIC
coiled coil region	607	652	N/A	INTRINSIC
low complexity region	807	822	N/A	INTRINSIC
low complexity region	1187	1198	N/A	INTRINSIC
low complexity region	1379	1390	N/A	INTRINSIC
low complexity region	1498	1512	N/A	INTRINSIC
low complexity region	1731	1744	N/A	INTRINSIC
low complexity region	1792	1804	N/A	INTRINSIC
Pfam:UCH	1930	2273	2.3e-44	PFAM
Pfam:UCH_1	1931	2229	1.1e-22	PFAM
low complexity region	2522	2544	N/A	INTRINSIC
low complexity region	2652	2659	N/A	INTRINSIC
Blast:Drf_GBD	2923	3096	2e-53	BLAST
low complexity region	3324	3337	N/A	INTRINSIC
coiled coil region	3352	3374	N/A	INTRINSIC

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.6%
20x: 98.7%

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 72 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1810024B03Rik	T	G	2: 127,028,710 (GRCm39)	D163A	possibly damaging	Het
Abce1	A	T	8: 80,414,537 (GRCm39)	I454N	probably damaging	Het
Acaca	A	G	11: 84,262,339 (GRCm39)	I1980M	probably damaging	Het
Adgrb2	C	T	4: 129,885,917 (GRCm39)	T19M	probably benign	Het
Agmo	T	A	12: 37,464,974 (GRCm39)	S417T	probably benign	Het
Akap8l	T	C	17: 32,552,068 (GRCm39)	E403G	probably damaging	Het
Art5	C	T	7: 101,747,711 (GRCm39)	A23T	possibly damaging	Het
Atg9a	T	C	1: 75,161,204 (GRCm39)	T681A	probably benign	Het
Atp11b	A	G	3: 35,832,256 (GRCm39)	Q37R	probably damaging	Het
Atp2a2	T	C	5: 122,629,829 (GRCm39)	E80G	probably benign	Het
AW551984	G	A	9: 39,511,071 (GRCm39)	P172L	possibly damaging	Het
Bace1	C	T	9: 45,769,743 (GRCm39)	R296C	probably damaging	Het
Ccser1	T	A	6: 61,288,840 (GRCm39)	H334Q	probably benign	Het
Chtf18	C	T	17: 25,942,491 (GRCm39)	R449H	probably damaging	Het
Cit	A	G	5: 116,122,881 (GRCm39)	H1384R	possibly damaging	Het
Cltc	A	G	11: 86,612,474 (GRCm39)	I524T	probably benign	Het
Dctn1	T	A	6: 83,160,042 (GRCm39)	I94N	probably damaging	Het
Dnhd1	A	T	7: 105,354,472 (GRCm39)	D3078V	probably damaging	Het
Dock7	G	A	4: 98,943,683 (GRCm39)	P520S		Het
Epb41l4a	C	A	18: 33,987,326 (GRCm39)	K350N	probably damaging	Het
Eprs1	T	A	1: 185,145,366 (GRCm39)	Y1130N	probably damaging	Het
Fcgrt	T	C	7: 44,744,797 (GRCm39)	T224A	probably damaging	Het
Flt1	T	A	5: 147,637,177 (GRCm39)	T39S	probably benign	Het
Fxyd1	T	C	7: 30,752,896 (GRCm39)	Y33C	probably damaging	Het
Gab2	T	A	7: 96,950,633 (GRCm39)	V442E	probably damaging	Het
Ganab	A	G	19: 8,892,076 (GRCm39)	D800G	probably benign	Het
Gata4	C	A	14: 63,478,186 (GRCm39)	A138S	probably benign	Het
Golga4	A	G	9: 118,385,131 (GRCm39)	H751R	possibly damaging	Het
H1f6	A	G	13: 23,880,455 (GRCm39)	R203G	possibly damaging	Het
Htra4	A	G	8: 25,527,093 (GRCm39)	V234A	possibly damaging	Het
Igkv4-74	A	T	6: 69,161,954 (GRCm39)	Y72N	probably damaging	Het
Iqsec3	T	C	6: 121,360,940 (GRCm39)	K973E	probably damaging	Het
Khdc1b	C	A	1: 21,455,065 (GRCm39)	T108K	probably benign	Het
Krtap5-1	ACAGGGCTTGCAGCAGCTGGACTGACAGCAGCAGGGCTTGCAGCAGCTGGACTGACAGCAGCAGGGCTTGCAGCAGCTGGACTGACAGCAG	ACAGGGCTTGCAGCAGCTGGACTGACAGCAGCAGGGCTTGCAGCAGCTGGACTGACAGCAG	7: 141,850,333 (GRCm39)		probably benign	Het
Kyat3	A	G	3: 142,432,066 (GRCm39)		probably null	Het
Lrba	T	A	3: 86,225,474 (GRCm39)	V666E	probably damaging	Het
Mettl25	T	A	10: 105,601,871 (GRCm39)	Y528F	probably benign	Het
Mms19	A	T	19: 41,940,904 (GRCm39)	Y619*	probably null	Het
Nlrp12	A	C	7: 3,277,020 (GRCm39)		probably null	Het
Nol10	C	T	12: 17,474,676 (GRCm39)	L623F	possibly damaging	Het
Oas1g	A	G	5: 121,024,063 (GRCm39)	F82S	probably damaging	Het
Or1j8	T	G	2: 36,191,772 (GRCm39)	S74A	probably benign	Het
Or5k3	C	T	16: 58,969,570 (GRCm39)	A119V	probably damaging	Het
Or8g18	G	A	9: 39,149,546 (GRCm39)	P58L	probably benign	Het
Oxr1	G	A	15: 41,686,863 (GRCm39)	E582K	probably damaging	Het
Pdia3	A	G	2: 121,262,838 (GRCm39)	D268G	possibly damaging	Het
Pramel13	T	C	4: 144,119,434 (GRCm39)	S378G	probably damaging	Het
Rcor3	A	G	1: 191,786,078 (GRCm39)	Y387H	probably damaging	Het
Rigi	T	A	4: 40,206,034 (GRCm39)	I853F	possibly damaging	Het
Rsf1	CGGCGGCGG	CGGCGGCGGGGGCGGCGG	7: 97,229,118 (GRCm39)		probably benign	Het
Rsl1	T	C	13: 67,330,284 (GRCm39)	L244P	possibly damaging	Het
Scn5a	G	T	9: 119,324,606 (GRCm39)	N1407K	probably damaging	Het
Sdcbp	C	T	4: 6,378,985 (GRCm39)	A24V	probably benign	Het
Slc22a8	A	G	19: 8,571,323 (GRCm39)	Y18C	possibly damaging	Het
Slc35d1	C	T	4: 103,072,044 (GRCm39)	R7H	probably damaging	Het
Slco6d1	A	T	1: 98,425,248 (GRCm39)	T599S	probably damaging	Het
Spata31d1e	C	T	13: 59,889,437 (GRCm39)	M794I	not run	Het
St18	T	A	1: 6,872,761 (GRCm39)	H165Q	probably benign	Het
Sub1	C	T	15: 11,986,589 (GRCm39)	R86K	probably damaging	Het
Tectb	G	A	19: 55,181,104 (GRCm39)	V148M		Het
Tgfb2	C	A	1: 186,362,954 (GRCm39)	G290V	possibly damaging	Het
Tgm7	T	C	2: 120,924,191 (GRCm39)	H577R	probably benign	Het
Tle2	T	C	10: 81,422,981 (GRCm39)	S460P	probably damaging	Het
Tmem221	C	A	8: 72,011,446 (GRCm39)	R3L	possibly damaging	Het
Tnfrsf19	C	A	14: 61,212,183 (GRCm39)	V156L	possibly damaging	Het
Trav6-5	A	G	14: 53,728,964 (GRCm39)	K75E	probably benign	Het
Trip10	G	A	17: 57,569,442 (GRCm39)	G488S	probably damaging	Het
Vps13d	T	C	4: 144,801,622 (GRCm39)	Q3532R		Het
Vps4a	A	T	8: 107,767,529 (GRCm39)	I163L	probably damaging	Het
Wrn	T	C	8: 33,814,454 (GRCm39)	H330R	probably benign	Het
Xpr1	T	C	1: 155,188,618 (GRCm39)	I341V	probably benign	Het
Zfyve9	T	C	4: 108,548,973 (GRCm39)	E105G	probably benign	Het

Other mutations in Usp34

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00092:Usp34	APN	11	23,386,020 (GRCm39)	missense	probably damaging	0.98
IGL00477:Usp34	APN	11	23,418,879 (GRCm39)	missense	probably damaging	0.99
IGL01307:Usp34	APN	11	23,367,676 (GRCm39)	missense	probably damaging	0.99
IGL01313:Usp34	APN	11	23,423,206 (GRCm39)	missense	probably damaging	1.00
IGL01794:Usp34	APN	11	23,386,020 (GRCm39)	missense	probably damaging	0.98
IGL01826:Usp34	APN	11	23,386,020 (GRCm39)	missense	probably damaging	0.98
IGL01827:Usp34	APN	11	23,386,020 (GRCm39)	missense	probably damaging	0.98
IGL01830:Usp34	APN	11	23,386,020 (GRCm39)	missense	probably damaging	0.98
IGL01867:Usp34	APN	11	23,334,411 (GRCm39)	missense	possibly damaging	0.77
IGL01939:Usp34	APN	11	23,295,141 (GRCm39)	splice site	probably benign
IGL01977:Usp34	APN	11	23,402,661 (GRCm39)	missense	probably damaging	1.00
IGL01985:Usp34	APN	11	23,402,565 (GRCm39)	missense	probably damaging	1.00
IGL02011:Usp34	APN	11	23,421,554 (GRCm39)	missense	probably damaging	0.99
IGL02302:Usp34	APN	11	23,417,243 (GRCm39)	missense	possibly damaging	0.91
IGL02423:Usp34	APN	11	23,304,900 (GRCm39)	missense	probably benign	0.11
IGL02491:Usp34	APN	11	23,382,630 (GRCm39)	missense	probably damaging	0.98
IGL02532:Usp34	APN	11	23,320,291 (GRCm39)	missense	probably damaging	0.99
IGL02561:Usp34	APN	11	23,301,652 (GRCm39)	missense	probably benign	0.09
IGL02706:Usp34	APN	11	23,338,659 (GRCm39)	splice site	probably benign
IGL02891:Usp34	APN	11	23,437,166 (GRCm39)	missense	probably benign	0.09
IGL03079:Usp34	APN	11	23,382,247 (GRCm39)	missense	possibly damaging	0.48
IGL03089:Usp34	APN	11	23,396,958 (GRCm39)	missense	possibly damaging	0.84
IGL03175:Usp34	APN	11	23,438,686 (GRCm39)	missense	probably benign
IGL03256:Usp34	APN	11	23,370,090 (GRCm39)	nonsense	probably null
IGL03280:Usp34	APN	11	23,304,897 (GRCm39)	missense	probably damaging	1.00
IGL03289:Usp34	APN	11	23,343,818 (GRCm39)	missense	possibly damaging	0.94
IGL03408:Usp34	APN	11	23,396,957 (GRCm39)	missense	possibly damaging	0.92
Chub	UTSW	11	23,414,686 (GRCm39)	missense	probably damaging	0.99
Cicione	UTSW	11	23,439,033 (GRCm39)	missense	possibly damaging	0.85
R5571_Usp34_680	UTSW	11	23,407,975 (GRCm39)	missense	probably damaging	0.99
R5713_Usp34_003	UTSW	11	23,293,515 (GRCm39)	missense	possibly damaging	0.94
Roebuck	UTSW	11	23,436,810 (GRCm39)	splice site	probably benign
stoat	UTSW	11	23,437,203 (GRCm39)	missense
tunnelvision	UTSW	11	23,396,968 (GRCm39)	missense
I2288:Usp34	UTSW	11	23,382,473 (GRCm39)	splice site	probably benign
R0047:Usp34	UTSW	11	23,414,403 (GRCm39)	missense	probably benign	0.34
R0047:Usp34	UTSW	11	23,414,403 (GRCm39)	missense	probably benign	0.34
R0099:Usp34	UTSW	11	23,313,111 (GRCm39)	missense	probably damaging	1.00
R0240:Usp34	UTSW	11	23,383,206 (GRCm39)	missense	probably damaging	0.99
R0240:Usp34	UTSW	11	23,383,206 (GRCm39)	missense	probably damaging	0.99
R0403:Usp34	UTSW	11	23,283,838 (GRCm39)	missense	possibly damaging	0.82
R0432:Usp34	UTSW	11	23,351,505 (GRCm39)	missense	probably damaging	0.99
R0446:Usp34	UTSW	11	23,417,207 (GRCm39)	missense	probably damaging	0.97
R0455:Usp34	UTSW	11	23,396,741 (GRCm39)	splice site	probably benign
R0470:Usp34	UTSW	11	23,386,001 (GRCm39)	missense	possibly damaging	0.94
R0472:Usp34	UTSW	11	23,334,509 (GRCm39)	splice site	probably benign
R0512:Usp34	UTSW	11	23,401,997 (GRCm39)	missense	probably benign	0.04
R0557:Usp34	UTSW	11	23,353,848 (GRCm39)	missense	probably damaging	0.98
R0562:Usp34	UTSW	11	23,382,406 (GRCm39)	splice site	probably benign
R0656:Usp34	UTSW	11	23,422,967 (GRCm39)	missense	probably damaging	0.99
R0693:Usp34	UTSW	11	23,402,637 (GRCm39)	missense	probably damaging	0.97
R0739:Usp34	UTSW	11	23,417,243 (GRCm39)	missense	possibly damaging	0.91
R1061:Usp34	UTSW	11	23,334,420 (GRCm39)	missense	possibly damaging	0.51
R1078:Usp34	UTSW	11	23,383,175 (GRCm39)	splice site	probably benign
R1223:Usp34	UTSW	11	23,396,464 (GRCm39)	splice site	probably null
R1295:Usp34	UTSW	11	23,334,477 (GRCm39)	missense	probably damaging	1.00
R1430:Usp34	UTSW	11	23,409,151 (GRCm39)	missense	probably damaging	0.97
R1445:Usp34	UTSW	11	23,301,629 (GRCm39)	missense	probably damaging	0.99
R1468:Usp34	UTSW	11	23,391,171 (GRCm39)	missense	probably damaging	1.00
R1468:Usp34	UTSW	11	23,391,171 (GRCm39)	missense	probably damaging	1.00
R1471:Usp34	UTSW	11	23,438,862 (GRCm39)	missense	probably benign	0.20
R1475:Usp34	UTSW	11	23,423,253 (GRCm39)	missense	probably damaging	0.99
R1628:Usp34	UTSW	11	23,438,725 (GRCm39)	missense	probably damaging	1.00
R1631:Usp34	UTSW	11	23,410,651 (GRCm39)	missense	probably damaging	0.99
R1655:Usp34	UTSW	11	23,325,051 (GRCm39)	missense	probably benign	0.05
R1741:Usp34	UTSW	11	23,314,103 (GRCm39)	missense	probably benign	0.00
R1854:Usp34	UTSW	11	23,376,153 (GRCm39)	missense	probably benign	0.24
R1867:Usp34	UTSW	11	23,311,593 (GRCm39)	missense	possibly damaging	0.82
R1869:Usp34	UTSW	11	23,314,479 (GRCm39)	missense	probably benign	0.37
R1870:Usp34	UTSW	11	23,314,479 (GRCm39)	missense	probably benign	0.37
R1871:Usp34	UTSW	11	23,314,479 (GRCm39)	missense	probably benign	0.37
R1967:Usp34	UTSW	11	23,314,503 (GRCm39)	missense	probably benign	0.01
R2051:Usp34	UTSW	11	23,414,468 (GRCm39)	missense	probably damaging	0.97
R2132:Usp34	UTSW	11	23,414,556 (GRCm39)	missense	possibly damaging	0.95
R2156:Usp34	UTSW	11	23,332,602 (GRCm39)	missense	probably damaging	0.98
R2205:Usp34	UTSW	11	23,335,147 (GRCm39)	missense	probably damaging	0.97
R2342:Usp34	UTSW	11	23,353,599 (GRCm39)	missense	possibly damaging	0.46
R3431:Usp34	UTSW	11	23,320,466 (GRCm39)	missense	possibly damaging	0.95
R3812:Usp34	UTSW	11	23,414,517 (GRCm39)	missense	possibly damaging	0.94
R3872:Usp34	UTSW	11	23,439,033 (GRCm39)	missense	possibly damaging	0.85
R3873:Usp34	UTSW	11	23,439,033 (GRCm39)	missense	possibly damaging	0.85
R3874:Usp34	UTSW	11	23,439,033 (GRCm39)	missense	possibly damaging	0.85
R3875:Usp34	UTSW	11	23,439,033 (GRCm39)	missense	possibly damaging	0.85
R3925:Usp34	UTSW	11	23,293,640 (GRCm39)	missense	probably benign	0.28
R3972:Usp34	UTSW	11	23,407,803 (GRCm39)	missense	probably damaging	1.00
R4018:Usp34	UTSW	11	23,439,033 (GRCm39)	missense	possibly damaging	0.85
R4042:Usp34	UTSW	11	23,439,033 (GRCm39)	missense	possibly damaging	0.85
R4155:Usp34	UTSW	11	23,367,676 (GRCm39)	missense	probably damaging	0.99
R4197:Usp34	UTSW	11	23,394,189 (GRCm39)	missense	probably damaging	0.98
R4352:Usp34	UTSW	11	23,270,727 (GRCm39)	missense	possibly damaging	0.73
R4379:Usp34	UTSW	11	23,334,499 (GRCm39)	missense	possibly damaging	0.52
R4444:Usp34	UTSW	11	23,385,998 (GRCm39)	missense	probably damaging	0.98
R4475:Usp34	UTSW	11	23,407,975 (GRCm39)	missense	possibly damaging	0.95
R4501:Usp34	UTSW	11	23,351,529 (GRCm39)	missense	probably damaging	1.00
R4527:Usp34	UTSW	11	23,371,257 (GRCm39)	missense	possibly damaging	0.57
R4603:Usp34	UTSW	11	23,414,633 (GRCm39)	missense	probably damaging	0.97
R4612:Usp34	UTSW	11	23,382,268 (GRCm39)	missense	probably damaging	0.99
R4673:Usp34	UTSW	11	23,314,480 (GRCm39)	small deletion	probably benign
R4707:Usp34	UTSW	11	23,437,215 (GRCm39)	missense	probably damaging	1.00
R4736:Usp34	UTSW	11	23,343,749 (GRCm39)	splice site	probably null
R4867:Usp34	UTSW	11	23,401,999 (GRCm39)	missense	probably benign	0.28
R4879:Usp34	UTSW	11	23,323,410 (GRCm39)	missense	possibly damaging	0.94
R4977:Usp34	UTSW	11	23,438,982 (GRCm39)	missense	probably damaging	1.00
R5004:Usp34	UTSW	11	23,414,586 (GRCm39)	missense	probably damaging	1.00
R5057:Usp34	UTSW	11	23,408,086 (GRCm39)	intron	probably benign
R5068:Usp34	UTSW	11	23,410,665 (GRCm39)	missense	possibly damaging	0.94
R5304:Usp34	UTSW	11	23,293,616 (GRCm39)	missense	probably damaging	1.00
R5320:Usp34	UTSW	11	23,283,739 (GRCm39)	missense	probably benign
R5327:Usp34	UTSW	11	23,418,846 (GRCm39)	missense	probably damaging	1.00
R5328:Usp34	UTSW	11	23,438,659 (GRCm39)	missense	probably benign	0.04
R5328:Usp34	UTSW	11	23,414,616 (GRCm39)	missense	probably benign	0.01
R5390:Usp34	UTSW	11	23,394,202 (GRCm39)	critical splice donor site	probably null
R5434:Usp34	UTSW	11	23,362,271 (GRCm39)	missense	probably damaging	0.99
R5523:Usp34	UTSW	11	23,299,198 (GRCm39)	missense	probably benign	0.39
R5567:Usp34	UTSW	11	23,438,336 (GRCm39)	missense	probably damaging	0.97
R5571:Usp34	UTSW	11	23,407,975 (GRCm39)	missense	probably damaging	0.99
R5645:Usp34	UTSW	11	23,325,024 (GRCm39)	missense	possibly damaging	0.86
R5713:Usp34	UTSW	11	23,293,515 (GRCm39)	missense	possibly damaging	0.94
R5719:Usp34	UTSW	11	23,304,846 (GRCm39)	missense	probably benign	0.00
R5813:Usp34	UTSW	11	23,371,340 (GRCm39)	missense	probably benign	0.38
R5921:Usp34	UTSW	11	23,414,686 (GRCm39)	missense	probably damaging	0.99
R5928:Usp34	UTSW	11	23,386,040 (GRCm39)	missense	probably damaging	0.98
R5944:Usp34	UTSW	11	23,313,089 (GRCm39)	missense	probably damaging	1.00
R6198:Usp34	UTSW	11	23,434,127 (GRCm39)	missense	probably damaging	1.00
R6229:Usp34	UTSW	11	23,396,778 (GRCm39)	missense	probably damaging	0.99
R6306:Usp34	UTSW	11	23,362,260 (GRCm39)	missense	possibly damaging	0.94
R6320:Usp34	UTSW	11	23,402,520 (GRCm39)	missense	probably damaging	0.98
R6341:Usp34	UTSW	11	23,331,353 (GRCm39)	missense	probably damaging	0.97
R6374:Usp34	UTSW	11	23,388,914 (GRCm39)	missense	probably damaging	1.00
R6398:Usp34	UTSW	11	23,438,666 (GRCm39)	missense	probably benign
R6438:Usp34	UTSW	11	23,314,266 (GRCm39)	missense	probably benign	0.02
R6668:Usp34	UTSW	11	23,410,659 (GRCm39)	missense	probably damaging	0.97
R6700:Usp34	UTSW	11	23,389,011 (GRCm39)	missense	probably damaging	1.00
R6783:Usp34	UTSW	11	23,362,318 (GRCm39)	missense	probably damaging	1.00
R6821:Usp34	UTSW	11	23,317,491 (GRCm39)	missense	possibly damaging	0.79
R6855:Usp34	UTSW	11	23,402,569 (GRCm39)	missense	possibly damaging	0.94
R6916:Usp34	UTSW	11	23,408,023 (GRCm39)	missense	probably damaging	0.98
R7020:Usp34	UTSW	11	23,343,954 (GRCm39)	missense	probably benign	0.05
R7026:Usp34	UTSW	11	23,311,622 (GRCm39)	missense	probably damaging	1.00
R7085:Usp34	UTSW	11	23,313,097 (GRCm39)	missense
R7101:Usp34	UTSW	11	23,376,183 (GRCm39)	missense
R7168:Usp34	UTSW	11	23,414,585 (GRCm39)	missense
R7192:Usp34	UTSW	11	23,410,571 (GRCm39)	missense
R7264:Usp34	UTSW	11	23,283,566 (GRCm39)	missense	probably benign	0.00
R7325:Usp34	UTSW	11	23,369,052 (GRCm39)	missense
R7343:Usp34	UTSW	11	23,438,868 (GRCm39)	missense
R7358:Usp34	UTSW	11	23,311,683 (GRCm39)	missense	probably damaging	0.99
R7369:Usp34	UTSW	11	23,382,361 (GRCm39)	missense
R7389:Usp34	UTSW	11	23,295,200 (GRCm39)	missense
R7459:Usp34	UTSW	11	23,314,458 (GRCm39)	missense	possibly damaging	0.53
R7517:Usp34	UTSW	11	23,396,968 (GRCm39)	missense
R7777:Usp34	UTSW	11	23,332,638 (GRCm39)	missense
R7810:Usp34	UTSW	11	23,362,314 (GRCm39)	missense
R7836:Usp34	UTSW	11	23,396,614 (GRCm39)	missense
R7862:Usp34	UTSW	11	23,414,718 (GRCm39)	missense
R7993:Usp34	UTSW	11	23,327,622 (GRCm39)	missense
R8050:Usp34	UTSW	11	23,396,787 (GRCm39)	missense
R8054:Usp34	UTSW	11	23,311,295 (GRCm39)	missense
R8239:Usp34	UTSW	11	23,396,750 (GRCm39)	missense
R8266:Usp34	UTSW	11	23,436,810 (GRCm39)	splice site	probably benign
R8347:Usp34	UTSW	11	23,362,345 (GRCm39)	missense
R8409:Usp34	UTSW	11	23,407,811 (GRCm39)	missense
R8692:Usp34	UTSW	11	23,379,325 (GRCm39)	missense
R8694:Usp34	UTSW	11	23,434,161 (GRCm39)	missense
R8734:Usp34	UTSW	11	23,394,184 (GRCm39)	missense
R8806:Usp34	UTSW	11	23,434,143 (GRCm39)	missense
R8914:Usp34	UTSW	11	23,293,604 (GRCm39)	missense
R8987:Usp34	UTSW	11	23,414,267 (GRCm39)	missense
R9013:Usp34	UTSW	11	23,320,302 (GRCm39)	missense
R9108:Usp34	UTSW	11	23,320,528 (GRCm39)	missense
R9264:Usp34	UTSW	11	23,439,064 (GRCm39)	missense
R9301:Usp34	UTSW	11	23,422,951 (GRCm39)	missense
R9375:Usp34	UTSW	11	23,437,203 (GRCm39)	missense
R9385:Usp34	UTSW	11	23,399,223 (GRCm39)	missense
R9500:Usp34	UTSW	11	23,331,337 (GRCm39)	missense	probably damaging	0.99
R9566:Usp34	UTSW	11	23,317,529 (GRCm39)	missense
R9629:Usp34	UTSW	11	23,314,364 (GRCm39)	missense
R9679:Usp34	UTSW	11	23,394,369 (GRCm39)	missense
R9680:Usp34	UTSW	11	23,317,385 (GRCm39)	missense	possibly damaging	0.94
R9686:Usp34	UTSW	11	23,424,351 (GRCm39)	missense
R9752:Usp34	UTSW	11	23,409,182 (GRCm39)	missense	probably benign	0.11
X0023:Usp34	UTSW	11	23,325,028 (GRCm39)	missense	possibly damaging	0.73
X0057:Usp34	UTSW	11	23,407,824 (GRCm39)	missense	possibly damaging	0.86
Z1176:Usp34	UTSW	11	23,423,221 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- CTCTGGGTGATGTCCTATAATGAAG -3'
(R):5'- CGTCACTTCATACTGGCAGTTG -3'

Sequencing Primer
(F):5'- AGCAATTAGACAAGCCATTTTAGTC -3'
(R):5'- CATACTGGCAGTTGTGTTAAAAGAGC -3'

Posted On

2019-11-12