Incidental Mutation 'R7733:Dsc2'
| ID |
596026 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dsc2
|
| Ensembl Gene |
ENSMUSG00000024331 |
| Gene Name |
desmocollin 2 |
| Synonyms |
Dsc2a, Dsc2b |
| MMRRC Submission |
045789-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7733 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
18 |
| Chromosomal Location |
20163690-20192611 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to C
at 20181373 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Valine
at position 145
(L145V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000042905
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000039247]
[ENSMUST00000075214]
[ENSMUST00000128464]
|
| AlphaFold |
P55292 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000039247
AA Change: L145V
PolyPhen 2
Score 0.159 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000042905
Gene: ENSMUSG00000024331
AA Change: L145V
| Domain | Start | End | E-Value | Type |
|---|
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
CA
|
156 |
241 |
4.66e-11 |
SMART |
|
CA
|
265 |
353 |
1.87e-24 |
SMART |
|
low complexity region
|
358 |
372 |
N/A |
INTRINSIC |
|
CA
|
376 |
470 |
1.27e-12 |
SMART |
|
CA
|
493 |
575 |
4.14e-17 |
SMART |
|
CA
|
594 |
676 |
1.49e-1 |
SMART |
|
transmembrane domain
|
696 |
718 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000075214
AA Change: L145V
PolyPhen 2
Score 0.192 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000074702
Gene: ENSMUSG00000024331
AA Change: L145V
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
28 |
N/A |
INTRINSIC |
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
CA
|
156 |
241 |
4.66e-11 |
SMART |
|
CA
|
265 |
353 |
1.87e-24 |
SMART |
|
low complexity region
|
358 |
372 |
N/A |
INTRINSIC |
|
CA
|
376 |
470 |
1.27e-12 |
SMART |
|
CA
|
493 |
575 |
4.14e-17 |
SMART |
|
CA
|
594 |
676 |
1.49e-1 |
SMART |
|
transmembrane domain
|
696 |
718 |
N/A |
INTRINSIC |
|
Pfam:Cadherin_C
|
730 |
901 |
3.7e-9 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000128464
|
| SMART Domains |
Protein: ENSMUSP00000123010
Gene: ENSMUSG00000024331
| Domain | Start | End | E-Value | Type |
|---|
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.3%
|
| Validation Efficiency |
100% (83/83) |
| MGI Phenotype |
FUNCTION: This gene encodes a member of the desmocollin protein subfamily. Desmocollins are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
|
| Allele List at MGI |
All alleles(2) : Targeted, other(2) |
| Other mutations in this stock |
Total: 81 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 5530400C23Rik |
T |
A |
6: 133,271,240 (GRCm39) |
S95T |
probably benign |
Het |
| Abca8a |
A |
G |
11: 109,945,413 (GRCm39) |
F1070L |
probably benign |
Het |
| Acsl3 |
G |
C |
1: 78,665,953 (GRCm39) |
|
probably null |
Het |
| Adarb2 |
T |
A |
13: 8,802,644 (GRCm39) |
S640T |
possibly damaging |
Het |
| Adgre5 |
T |
C |
8: 84,456,025 (GRCm39) |
D257G |
probably benign |
Het |
| Adora2b |
A |
T |
11: 62,156,165 (GRCm39) |
I205F |
possibly damaging |
Het |
| Asb14 |
A |
G |
14: 26,634,309 (GRCm39) |
M505V |
probably benign |
Het |
| Atrnl1 |
T |
C |
19: 57,690,420 (GRCm39) |
V876A |
probably benign |
Het |
| AU040320 |
A |
G |
4: 126,729,322 (GRCm39) |
N495D |
possibly damaging |
Het |
| Bcam |
A |
T |
7: 19,494,313 (GRCm39) |
V361E |
probably benign |
Het |
| Ccdc7a |
T |
A |
8: 129,719,533 (GRCm39) |
E247V |
probably damaging |
Het |
| Cd84 |
T |
A |
1: 171,668,226 (GRCm39) |
M1K |
probably null |
Het |
| Cfap43 |
C |
T |
19: 47,886,432 (GRCm39) |
R61H |
possibly damaging |
Het |
| Clec4a1 |
A |
G |
6: 122,909,109 (GRCm39) |
D159G |
possibly damaging |
Het |
| Ctcfl |
C |
T |
2: 172,958,985 (GRCm39) |
R247Q |
probably benign |
Het |
| Ctdnep1 |
G |
A |
11: 69,880,835 (GRCm39) |
R236Q |
probably damaging |
Het |
| Cwf19l2 |
A |
T |
9: 3,450,066 (GRCm39) |
H589L |
probably benign |
Het |
| Cyp2u1 |
G |
T |
3: 131,096,676 (GRCm39) |
A34E |
probably benign |
Het |
| Cyp4x1 |
A |
G |
4: 114,977,391 (GRCm39) |
S281P |
possibly damaging |
Het |
| Dag1 |
T |
C |
9: 108,086,047 (GRCm39) |
T365A |
probably benign |
Het |
| Dhx57 |
A |
T |
17: 80,572,503 (GRCm39) |
|
probably null |
Het |
| Dnajb1 |
T |
G |
8: 84,335,006 (GRCm39) |
S16A |
probably benign |
Het |
| Eefsec |
T |
C |
6: 88,353,202 (GRCm39) |
T156A |
possibly damaging |
Het |
| Eif6 |
T |
A |
2: 155,665,152 (GRCm39) |
D169V |
probably benign |
Het |
| Ell3 |
C |
A |
2: 121,273,001 (GRCm39) |
G3V |
possibly damaging |
Het |
| Eprs1 |
A |
T |
1: 185,129,358 (GRCm39) |
H615L |
probably benign |
Het |
| Fbxw10 |
A |
G |
11: 62,764,223 (GRCm39) |
Y630C |
unknown |
Het |
| Fcgbpl1 |
A |
T |
7: 27,839,390 (GRCm39) |
D401V |
probably damaging |
Het |
| G6pc2 |
C |
T |
2: 69,050,527 (GRCm39) |
Q51* |
probably null |
Het |
| Glt8d1 |
C |
T |
14: 30,723,935 (GRCm39) |
|
probably benign |
Het |
| Gpr4 |
T |
C |
7: 18,956,635 (GRCm39) |
Y186H |
probably damaging |
Het |
| Grhpr |
T |
C |
4: 44,981,494 (GRCm39) |
|
probably benign |
Het |
| Gsdma3 |
A |
G |
11: 98,526,041 (GRCm39) |
H264R |
probably damaging |
Het |
| Hcfc2 |
A |
G |
10: 82,575,013 (GRCm39) |
Y224C |
probably benign |
Het |
| Helz2 |
A |
G |
2: 180,872,148 (GRCm39) |
F2608S |
possibly damaging |
Het |
| Herc2 |
C |
T |
7: 55,838,412 (GRCm39) |
T3313M |
probably damaging |
Het |
| Hmgcl |
A |
T |
4: 135,687,394 (GRCm39) |
H223L |
probably benign |
Het |
| Igf2r |
A |
G |
17: 12,958,256 (GRCm39) |
V139A |
possibly damaging |
Het |
| Iqcn |
A |
G |
8: 71,170,100 (GRCm39) |
T1397A |
possibly damaging |
Het |
| Kif5a |
T |
A |
10: 127,072,609 (GRCm39) |
T727S |
probably benign |
Het |
| Kifc1 |
G |
A |
17: 34,102,543 (GRCm39) |
R357W |
probably damaging |
Het |
| Krt81 |
T |
A |
15: 101,361,395 (GRCm39) |
S62C |
probably damaging |
Het |
| Lgi2 |
T |
C |
5: 52,695,873 (GRCm39) |
N362S |
probably benign |
Het |
| Lig1 |
G |
T |
7: 13,030,157 (GRCm39) |
R378L |
possibly damaging |
Het |
| Map3k13 |
C |
T |
16: 21,740,436 (GRCm39) |
R588C |
probably damaging |
Het |
| Mov10l1 |
T |
A |
15: 88,909,004 (GRCm39) |
F1008L |
probably damaging |
Het |
| Nr4a2 |
A |
G |
2: 57,002,333 (GRCm39) |
V40A |
probably benign |
Het |
| Nrde2 |
A |
T |
12: 100,110,399 (GRCm39) |
C206S |
possibly damaging |
Het |
| Or4f14d |
C |
T |
2: 111,960,386 (GRCm39) |
V257I |
probably benign |
Het |
| Parp1 |
T |
C |
1: 180,427,777 (GRCm39) |
|
probably null |
Het |
| Pcdhb12 |
A |
G |
18: 37,570,089 (GRCm39) |
T412A |
probably damaging |
Het |
| Plekhh2 |
T |
A |
17: 84,890,952 (GRCm39) |
Y839* |
probably null |
Het |
| Pnpla6 |
T |
A |
8: 3,572,660 (GRCm39) |
F316I |
probably benign |
Het |
| Prcp |
C |
T |
7: 92,550,506 (GRCm39) |
T101M |
probably damaging |
Het |
| Prex2 |
G |
T |
1: 11,252,183 (GRCm39) |
R1076L |
probably benign |
Het |
| Prpf40b |
T |
C |
15: 99,206,224 (GRCm39) |
|
probably null |
Het |
| Psd3 |
T |
G |
8: 68,573,568 (GRCm39) |
K204N |
possibly damaging |
Het |
| Ptpro |
C |
A |
6: 137,391,284 (GRCm39) |
C801* |
probably null |
Het |
| Ptprt |
A |
G |
2: 161,417,707 (GRCm39) |
V923A |
probably damaging |
Het |
| Ptprz1 |
T |
A |
6: 23,000,383 (GRCm39) |
D824E |
probably benign |
Het |
| Rasgrf1 |
A |
G |
9: 89,863,780 (GRCm39) |
D582G |
probably benign |
Het |
| Rfc2 |
T |
C |
5: 134,622,070 (GRCm39) |
L183P |
probably damaging |
Het |
| Rnf114 |
T |
C |
2: 167,354,438 (GRCm39) |
V173A |
probably damaging |
Het |
| Scn3a |
T |
A |
2: 65,338,994 (GRCm39) |
I562F |
probably benign |
Het |
| Setmar |
T |
C |
6: 108,053,088 (GRCm39) |
I194T |
probably damaging |
Het |
| Sptb |
A |
T |
12: 76,644,695 (GRCm39) |
|
probably null |
Het |
| Sptbn2 |
C |
G |
19: 4,799,040 (GRCm39) |
R2037G |
probably benign |
Het |
| Sptlc3 |
G |
T |
2: 139,473,288 (GRCm39) |
M512I |
possibly damaging |
Het |
| Svep1 |
C |
A |
4: 58,049,239 (GRCm39) |
A3423S |
probably benign |
Het |
| Sycp1 |
T |
C |
3: 102,803,278 (GRCm39) |
T511A |
probably benign |
Het |
| Synm |
T |
A |
7: 67,385,693 (GRCm39) |
|
probably null |
Het |
| Tada1 |
C |
T |
1: 166,217,511 (GRCm39) |
P216L |
probably damaging |
Het |
| Tas2r117 |
T |
A |
6: 132,780,138 (GRCm39) |
M92K |
probably benign |
Het |
| Thoc2l |
T |
C |
5: 104,667,826 (GRCm39) |
F783L |
possibly damaging |
Het |
| Thsd1 |
T |
C |
8: 22,748,737 (GRCm39) |
L536P |
probably damaging |
Het |
| Timp2 |
T |
G |
11: 118,208,355 (GRCm39) |
|
probably null |
Het |
| Trak1 |
T |
A |
9: 121,196,291 (GRCm39) |
V41D |
possibly damaging |
Het |
| Ubqln3 |
T |
A |
7: 103,790,283 (GRCm39) |
L602F |
probably damaging |
Het |
| Vmn2r59 |
A |
G |
7: 41,661,443 (GRCm39) |
F791L |
probably benign |
Het |
| Wbp4 |
A |
G |
14: 79,714,480 (GRCm39) |
|
probably null |
Het |
| Zng1 |
T |
C |
19: 24,918,158 (GRCm39) |
D204G |
probably damaging |
Het |
|
| Other mutations in Dsc2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00802:Dsc2
|
APN |
18 |
20,174,854 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL00826:Dsc2
|
APN |
18 |
20,168,372 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00852:Dsc2
|
APN |
18 |
20,167,740 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01082:Dsc2
|
APN |
18 |
20,176,849 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01328:Dsc2
|
APN |
18 |
20,181,343 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01338:Dsc2
|
APN |
18 |
20,180,214 (GRCm39) |
missense |
probably benign |
0.19 |
|
IGL01727:Dsc2
|
APN |
18 |
20,171,257 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01766:Dsc2
|
APN |
18 |
20,179,399 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
IGL02228:Dsc2
|
APN |
18 |
20,176,790 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02560:Dsc2
|
APN |
18 |
20,178,596 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02794:Dsc2
|
APN |
18 |
20,174,788 (GRCm39) |
missense |
probably damaging |
1.00 |
|
3-1:Dsc2
|
UTSW |
18 |
20,180,136 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
PIT4305001:Dsc2
|
UTSW |
18 |
20,179,300 (GRCm39) |
missense |
probably damaging |
0.96 |
|
PIT4431001:Dsc2
|
UTSW |
18 |
20,179,334 (GRCm39) |
nonsense |
probably null |
|
|
R0288:Dsc2
|
UTSW |
18 |
20,166,177 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0542:Dsc2
|
UTSW |
18 |
20,184,283 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0562:Dsc2
|
UTSW |
18 |
20,174,594 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0697:Dsc2
|
UTSW |
18 |
20,174,509 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0940:Dsc2
|
UTSW |
18 |
20,183,116 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1081:Dsc2
|
UTSW |
18 |
20,166,352 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1140:Dsc2
|
UTSW |
18 |
20,165,269 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1515:Dsc2
|
UTSW |
18 |
20,178,622 (GRCm39) |
missense |
probably benign |
0.40 |
|
R1515:Dsc2
|
UTSW |
18 |
20,167,758 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1558:Dsc2
|
UTSW |
18 |
20,183,208 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1654:Dsc2
|
UTSW |
18 |
20,179,303 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2061:Dsc2
|
UTSW |
18 |
20,165,456 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2089:Dsc2
|
UTSW |
18 |
20,166,351 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R2091:Dsc2
|
UTSW |
18 |
20,166,351 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R2091:Dsc2
|
UTSW |
18 |
20,166,351 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R2172:Dsc2
|
UTSW |
18 |
20,178,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2247:Dsc2
|
UTSW |
18 |
20,168,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2472:Dsc2
|
UTSW |
18 |
20,178,526 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2927:Dsc2
|
UTSW |
18 |
20,178,558 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3611:Dsc2
|
UTSW |
18 |
20,165,408 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3961:Dsc2
|
UTSW |
18 |
20,184,284 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3963:Dsc2
|
UTSW |
18 |
20,184,284 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4353:Dsc2
|
UTSW |
18 |
20,183,125 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4362:Dsc2
|
UTSW |
18 |
20,183,214 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4612:Dsc2
|
UTSW |
18 |
20,174,876 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4613:Dsc2
|
UTSW |
18 |
20,174,876 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4752:Dsc2
|
UTSW |
18 |
20,171,279 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4946:Dsc2
|
UTSW |
18 |
20,183,214 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5056:Dsc2
|
UTSW |
18 |
20,183,199 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5267:Dsc2
|
UTSW |
18 |
20,167,640 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5445:Dsc2
|
UTSW |
18 |
20,168,360 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R5507:Dsc2
|
UTSW |
18 |
20,179,336 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5575:Dsc2
|
UTSW |
18 |
20,168,447 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5781:Dsc2
|
UTSW |
18 |
20,165,567 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6102:Dsc2
|
UTSW |
18 |
20,180,165 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6129:Dsc2
|
UTSW |
18 |
20,178,487 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6362:Dsc2
|
UTSW |
18 |
20,168,520 (GRCm39) |
nonsense |
probably null |
|
|
R6433:Dsc2
|
UTSW |
18 |
20,184,232 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6513:Dsc2
|
UTSW |
18 |
20,179,295 (GRCm39) |
missense |
probably benign |
|
|
R6615:Dsc2
|
UTSW |
18 |
20,165,576 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R6619:Dsc2
|
UTSW |
18 |
20,165,335 (GRCm39) |
missense |
probably benign |
0.22 |
|
R6665:Dsc2
|
UTSW |
18 |
20,183,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6961:Dsc2
|
UTSW |
18 |
20,171,279 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7179:Dsc2
|
UTSW |
18 |
20,168,332 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7275:Dsc2
|
UTSW |
18 |
20,184,236 (GRCm39) |
nonsense |
probably null |
|
|
R7352:Dsc2
|
UTSW |
18 |
20,168,392 (GRCm39) |
missense |
probably benign |
0.39 |
|
R7386:Dsc2
|
UTSW |
18 |
20,174,983 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R7496:Dsc2
|
UTSW |
18 |
20,168,451 (GRCm39) |
nonsense |
probably null |
|
|
R7510:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R7580:Dsc2
|
UTSW |
18 |
20,183,130 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7718:Dsc2
|
UTSW |
18 |
20,174,835 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7733:Dsc2
|
UTSW |
18 |
20,181,372 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7818:Dsc2
|
UTSW |
18 |
20,183,189 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7852:Dsc2
|
UTSW |
18 |
20,179,342 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R7998:Dsc2
|
UTSW |
18 |
20,167,720 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R8029:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8030:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8031:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8032:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8059:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8060:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8061:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8062:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8063:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8082:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8090:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8114:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8115:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8116:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8117:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8118:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8328:Dsc2
|
UTSW |
18 |
20,165,576 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R8545:Dsc2
|
UTSW |
18 |
20,167,722 (GRCm39) |
nonsense |
probably null |
|
|
R9005:Dsc2
|
UTSW |
18 |
20,171,151 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9017:Dsc2
|
UTSW |
18 |
20,176,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9111:Dsc2
|
UTSW |
18 |
20,167,764 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9396:Dsc2
|
UTSW |
18 |
20,174,773 (GRCm39) |
nonsense |
probably null |
|
|
R9487:Dsc2
|
UTSW |
18 |
20,180,276 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9663:Dsc2
|
UTSW |
18 |
20,171,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Dsc2
|
UTSW |
18 |
20,179,361 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1176:Dsc2
|
UTSW |
18 |
20,168,356 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCATGGTACCTAAACCTTCCATC -3'
(R):5'- CCCTAGCCAATCCTTATGAGAG -3'
Sequencing Primer
(F):5'- TCACTCAAAGTCTCAAGTATAGCAGG -3'
(R):5'- TCCTTATGAGAGGAGACAAATGTATC -3'
|
| Posted On |
2019-11-12 |
Incidental Mutation