Mutagenetix > Incidental Mutation

Incidental Mutation 'R7734:Tenm3'

596055

Institutional Source

Beutler Lab

Gene Symbol

Tenm3

Ensembl Gene

ENSMUSG00000031561

Gene Name

teneurin transmembrane protein 3

Synonyms

Odz3, Ten-m3, 2610100B16Rik

MMRRC Submission

045790-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.472) question?

Stock #

R7734 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

48680717-49296986 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 49099368 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Cysteine to Arginine at position 146 (C146R)

Ref Sequence

ENSEMBL: ENSMUSP00000033965 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000033965] [ENSMUST00000190840] [ENSMUST00000211812]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000033965
AA Change: C146R

PolyPhen 2 Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000033965
Gene: ENSMUSG00000031561
AA Change: C146R

Domain	Start	End	E-Value	Type
Pfam:Ten_N	11	177	6.9e-91	PFAM
Pfam:Ten_N	171	308	1e-72	PFAM
transmembrane domain	309	331	N/A	INTRINSIC
EGF	517	545	2.32e-1	SMART
EGF_like	548	576	4.11e1	SMART
EGF	581	610	1.69e1	SMART
EGF	613	642	1.35e-2	SMART
EGF	647	677	6.11e-1	SMART
EGF	680	708	7.95e0	SMART
EGF	711	739	1.28e1	SMART
EGF	751	783	1.64e-1	SMART
PDB:1RWL\|A	1276	1511	9e-6	PDB
low complexity region	2593	2602	N/A	INTRINSIC
Pfam:Tox-GHH	2631	2708	1.5e-34	PFAM

Predicted Effect

unknown
Transcript: ENSMUST00000190840
AA Change: C146R

SMART Domains

Protein: ENSMUSP00000140141
Gene: ENSMUSG00000031561
AA Change: C146R

Domain	Start	End	E-Value	Type
Pfam:Ten_N	10	182	7.6e-77	PFAM
Pfam:Ten_N	168	308	6.6e-50	PFAM
transmembrane domain	309	331	N/A	INTRINSIC
EGF	517	545	2.32e-1	SMART
EGF_like	548	576	4.11e1	SMART
EGF	581	610	1.69e1	SMART
EGF	613	642	1.35e-2	SMART
EGF	647	677	6.11e-1	SMART
EGF	680	708	7.95e0	SMART
EGF	711	739	1.28e1	SMART
EGF	751	783	1.64e-1	SMART
PDB:1RWL\|A	1276	1511	9e-6	PDB
low complexity region	2593	2602	N/A	INTRINSIC
Pfam:Tox-GHH	2630	2708	3.2e-35	PFAM

Predicted Effect

unknown
Transcript: ENSMUST00000211812
AA Change: C146R

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.7%
20x: 99.1%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a large transmembrane protein that may be involved in the regulation of neuronal development. Mutation in this gene causes microphthalmia. [provided by RefSeq, Aug 2015]
PHENOTYPE: Mice homozygous for a null mutation display abnormal ipsilateral retinal ganglion cell projections and impaired performance in visually mediated behavioral tasks. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 58 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Anxa2	T	C	9: 69,398,764 (GRCm39)	Y333H	probably benign	Het
Arid1a	A	T	4: 133,408,679 (GRCm39)	F1558I	unknown	Het
Aste1	A	G	9: 105,274,678 (GRCm39)	D306G	probably damaging	Het
Atp2a2	A	G	5: 122,596,590 (GRCm39)	V843A	possibly damaging	Het
Atrip	T	A	9: 108,894,574 (GRCm39)	H451L	probably benign	Het
Cdc42bpb	T	C	12: 111,295,664 (GRCm39)	D200G	probably damaging	Het
Ceacam19	A	C	7: 19,620,520 (GRCm39)	M37R	probably benign	Het
Cemip	G	A	7: 83,606,872 (GRCm39)	R782*	probably null	Het
Cpe	A	T	8: 65,070,654 (GRCm39)	I197N	probably benign	Het
Csmd2	C	A	4: 128,445,850 (GRCm39)	P3307T		Het
Cyp4a12b	C	A	4: 115,268,937 (GRCm39)	Q20K	possibly damaging	Het
Dcaf1	T	C	9: 106,715,878 (GRCm39)	Y332H	probably damaging	Het
Dclk3	A	G	9: 111,298,163 (GRCm39)	H569R	probably damaging	Het
Dcp1b	A	G	6: 119,192,244 (GRCm39)	S387G	probably benign	Het
Ddx24	A	G	12: 103,383,819 (GRCm39)	M590T	possibly damaging	Het
Dixdc1	T	G	9: 50,613,268 (GRCm39)	Q229P	probably damaging	Het
Dnase1l3	T	C	14: 7,977,144 (GRCm38)	R181G	probably benign	Het
Dzip1l	A	T	9: 99,549,735 (GRCm39)	D735V	probably damaging	Het
Edem3	T	C	1: 151,694,336 (GRCm39)	S890P	probably benign	Het
Fuom	A	G	7: 139,679,455 (GRCm39)	L155P	unknown	Het
Gm6408	C	A	5: 146,421,160 (GRCm39)	S263*	probably null	Het
Helz	C	G	11: 107,576,248 (GRCm39)	S1814R	unknown	Het
Hrc	T	C	7: 44,986,100 (GRCm39)	L417P	probably benign	Het
Igdcc4	A	C	9: 65,039,035 (GRCm39)	H894P	probably damaging	Het
Lgr6	C	A	1: 134,930,981 (GRCm39)	V296L	probably damaging	Het
Map3k4	T	A	17: 12,482,998 (GRCm39)	Y573F	probably damaging	Het
Mest	T	C	6: 30,746,299 (GRCm39)	Y296H	unknown	Het
Mettl21a	C	T	1: 64,647,288 (GRCm39)	V90M	probably damaging	Het
Mfsd4b1	A	T	10: 39,883,374 (GRCm39)	N25K	probably damaging	Het
Mmd	T	A	11: 90,167,579 (GRCm39)	F203I	probably damaging	Het
Myo15a	G	A	11: 60,401,108 (GRCm39)	V3028M	probably benign	Het
Nlrp1a	T	A	11: 70,998,826 (GRCm39)	N859I	unknown	Het
Nrcam	T	C	12: 44,584,034 (GRCm39)	L36P	possibly damaging	Het
Nup107	C	A	10: 117,593,917 (GRCm39)	E759*	probably null	Het
Or14a259	A	G	7: 86,013,476 (GRCm39)	I23T	not run	Het
Pcdh7	T	G	5: 57,876,976 (GRCm39)	I177S	probably damaging	Het
Pde6a	T	C	18: 61,365,938 (GRCm39)	I221T	probably benign	Het
Ptpn13	A	T	5: 103,709,828 (GRCm39)	N1497I	probably damaging	Het
Rmc1	T	A	18: 12,322,320 (GRCm39)	I591N	possibly damaging	Het
Rpl4	T	A	9: 64,084,661 (GRCm39)	H245Q	probably benign	Het
Rsf1	C	CCACGGCGGG	7: 97,229,115 (GRCm39)		probably benign	Het
Scara5	A	G	14: 65,968,600 (GRCm39)	D291G	possibly damaging	Het
Septin14	T	A	5: 129,760,583 (GRCm39)	I422L	probably benign	Het
Serpina1e	T	C	12: 103,917,151 (GRCm39)	K173E	probably benign	Het
Slc5a1	C	T	5: 33,318,279 (GRCm39)	T644I	probably benign	Het
Slc6a13	A	T	6: 121,314,334 (GRCm39)	T590S	probably benign	Het
Smarca4	C	T	9: 21,578,658 (GRCm39)	T938I	possibly damaging	Het
Stxbp1	A	T	2: 32,691,832 (GRCm39)	D453E	probably benign	Het
Tcf12	C	A	9: 71,829,943 (GRCm39)	V173L	probably benign	Het
Trim11	T	C	11: 58,869,180 (GRCm39)	C39R	probably damaging	Het
Trim37	A	G	11: 87,068,821 (GRCm39)	Y389C	probably damaging	Het
Ttll8	C	T	15: 88,798,368 (GRCm39)	G789D	probably damaging	Het
Tubb2a	C	T	13: 34,258,776 (GRCm39)	S338N	probably benign	Het
Ulk2	G	A	11: 61,744,127 (GRCm39)	Q50*	probably null	Het
Urgcp	T	C	11: 5,666,406 (GRCm39)	D687G	probably benign	Het
Usp13	C	T	3: 32,892,054 (GRCm39)	H78Y	probably benign	Het
Vmn2r100	T	A	17: 19,742,296 (GRCm39)	D223E	probably benign	Het
Vwc2	G	A	11: 11,065,929 (GRCm39)	A6T	possibly damaging	Het

Other mutations in Tenm3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00272:Tenm3	APN	8	48,870,095 (GRCm39)	missense	probably damaging	1.00
IGL00538:Tenm3	APN	8	48,689,060 (GRCm39)	missense	probably damaging	1.00
IGL00719:Tenm3	APN	8	48,732,077 (GRCm39)	missense	probably benign	0.39
IGL00720:Tenm3	APN	8	48,729,456 (GRCm39)	missense	probably damaging	0.98
IGL00870:Tenm3	APN	8	48,870,167 (GRCm39)	missense	probably benign	0.00
IGL00976:Tenm3	APN	8	48,709,876 (GRCm39)	missense	probably benign	0.14
IGL01469:Tenm3	APN	8	48,689,458 (GRCm39)	missense	probably damaging	1.00
IGL01508:Tenm3	APN	8	48,729,680 (GRCm39)	missense	probably benign	0.09
IGL01590:Tenm3	APN	8	48,681,837 (GRCm39)	missense	probably damaging	1.00
IGL01610:Tenm3	APN	8	48,707,512 (GRCm39)	missense	probably damaging	1.00
IGL01874:Tenm3	APN	8	48,689,793 (GRCm39)	nonsense	probably null
IGL01892:Tenm3	APN	8	48,729,431 (GRCm39)	missense	probably benign	0.09
IGL02098:Tenm3	APN	8	48,729,611 (GRCm39)	missense	possibly damaging	0.94
IGL02382:Tenm3	APN	8	48,688,511 (GRCm39)	missense	probably damaging	1.00
IGL02397:Tenm3	APN	8	48,689,729 (GRCm39)	missense	possibly damaging	0.94
IGL02475:Tenm3	APN	8	48,732,233 (GRCm39)	splice site	probably benign
IGL02502:Tenm3	APN	8	48,741,051 (GRCm39)	missense	probably damaging	1.00
IGL02508:Tenm3	APN	8	48,752,674 (GRCm39)	missense	probably benign	0.30
IGL02543:Tenm3	APN	8	48,751,991 (GRCm39)	missense	probably damaging	1.00
IGL02723:Tenm3	APN	8	48,729,938 (GRCm39)	missense	probably benign	0.02
IGL03037:Tenm3	APN	8	48,751,913 (GRCm39)	missense	possibly damaging	0.90
IGL03160:Tenm3	APN	8	49,099,453 (GRCm39)	missense	probably benign	0.05
IGL03268:Tenm3	APN	8	48,688,558 (GRCm39)	missense	probably damaging	1.00
IGL02988:Tenm3	UTSW	8	48,688,381 (GRCm39)	missense	probably damaging	0.99
PIT4431001:Tenm3	UTSW	8	48,688,642 (GRCm39)	missense	probably damaging	1.00
PIT4504001:Tenm3	UTSW	8	48,746,692 (GRCm39)	missense	probably damaging	1.00
R0079:Tenm3	UTSW	8	48,796,380 (GRCm39)	missense	possibly damaging	0.90
R0121:Tenm3	UTSW	8	48,795,694 (GRCm39)	missense	probably damaging	0.99
R0123:Tenm3	UTSW	8	49,127,507 (GRCm39)	missense	probably damaging	1.00
R0134:Tenm3	UTSW	8	49,127,507 (GRCm39)	missense	probably damaging	1.00
R0147:Tenm3	UTSW	8	48,689,755 (GRCm39)	missense	probably damaging	1.00
R0148:Tenm3	UTSW	8	48,689,755 (GRCm39)	missense	probably damaging	1.00
R0309:Tenm3	UTSW	8	48,794,069 (GRCm39)	missense	probably damaging	1.00
R0322:Tenm3	UTSW	8	48,689,947 (GRCm39)	splice site	probably benign
R0335:Tenm3	UTSW	8	48,685,140 (GRCm39)	missense	probably damaging	1.00
R0355:Tenm3	UTSW	8	48,682,010 (GRCm39)	missense	probably damaging	1.00
R0411:Tenm3	UTSW	8	48,740,826 (GRCm39)	missense	possibly damaging	0.61
R0505:Tenm3	UTSW	8	48,794,195 (GRCm39)	splice site	probably benign
R0573:Tenm3	UTSW	8	49,127,434 (GRCm39)	splice site	probably benign
R0599:Tenm3	UTSW	8	48,730,745 (GRCm39)	missense	probably damaging	1.00
R0616:Tenm3	UTSW	8	48,729,191 (GRCm39)	missense	possibly damaging	0.76
R0637:Tenm3	UTSW	8	48,689,560 (GRCm39)	missense	probably damaging	1.00
R0726:Tenm3	UTSW	8	48,689,629 (GRCm39)	missense	probably damaging	1.00
R0840:Tenm3	UTSW	8	48,788,777 (GRCm39)	missense	probably damaging	0.99
R0981:Tenm3	UTSW	8	48,752,000 (GRCm39)	missense	probably damaging	1.00
R1006:Tenm3	UTSW	8	48,681,577 (GRCm39)	missense	probably damaging	1.00
R1199:Tenm3	UTSW	8	48,688,617 (GRCm39)	missense	probably damaging	0.99
R1223:Tenm3	UTSW	8	48,693,431 (GRCm39)	missense	possibly damaging	0.72
R1240:Tenm3	UTSW	8	48,740,928 (GRCm39)	missense	possibly damaging	0.74
R1394:Tenm3	UTSW	8	48,729,435 (GRCm39)	missense	probably benign
R1455:Tenm3	UTSW	8	48,732,083 (GRCm39)	missense	possibly damaging	0.87
R1459:Tenm3	UTSW	8	48,689,006 (GRCm39)	missense	probably damaging	1.00
R1473:Tenm3	UTSW	8	48,763,660 (GRCm39)	missense	probably damaging	1.00
R1501:Tenm3	UTSW	8	48,796,351 (GRCm39)	missense	probably damaging	0.99
R1507:Tenm3	UTSW	8	48,740,857 (GRCm39)	missense	probably benign	0.01
R1522:Tenm3	UTSW	8	48,848,611 (GRCm39)	missense	probably damaging	1.00
R1524:Tenm3	UTSW	8	48,682,016 (GRCm39)	missense	possibly damaging	0.92
R1553:Tenm3	UTSW	8	48,689,456 (GRCm39)	missense	probably damaging	1.00
R1572:Tenm3	UTSW	8	48,682,028 (GRCm39)	missense	possibly damaging	0.94
R1583:Tenm3	UTSW	8	48,732,109 (GRCm39)	missense	probably benign	0.09
R1676:Tenm3	UTSW	8	48,870,154 (GRCm39)	missense	possibly damaging	0.83
R1732:Tenm3	UTSW	8	48,763,669 (GRCm39)	missense	probably damaging	1.00
R1768:Tenm3	UTSW	8	48,685,139 (GRCm39)	missense	probably damaging	1.00
R1777:Tenm3	UTSW	8	48,870,214 (GRCm39)	missense	probably benign	0.05
R1793:Tenm3	UTSW	8	49,127,579 (GRCm39)	missense	probably damaging	0.98
R1801:Tenm3	UTSW	8	48,729,291 (GRCm39)	missense	probably benign	0.39
R1863:Tenm3	UTSW	8	48,729,381 (GRCm39)	missense	probably benign	0.20
R1898:Tenm3	UTSW	8	48,763,796 (GRCm39)	missense	probably damaging	1.00
R1971:Tenm3	UTSW	8	48,689,348 (GRCm39)	missense	probably damaging	1.00
R1972:Tenm3	UTSW	8	48,681,626 (GRCm39)	missense	probably damaging	1.00
R1996:Tenm3	UTSW	8	48,681,703 (GRCm39)	missense	probably damaging	1.00
R2061:Tenm3	UTSW	8	48,795,291 (GRCm39)	critical splice donor site	probably null
R2109:Tenm3	UTSW	8	48,796,384 (GRCm39)	missense	possibly damaging	0.94
R2124:Tenm3	UTSW	8	48,870,041 (GRCm39)	critical splice donor site	probably null
R2190:Tenm3	UTSW	8	48,848,579 (GRCm39)	missense	probably damaging	1.00
R2204:Tenm3	UTSW	8	49,127,585 (GRCm39)	missense	probably benign	0.17
R2233:Tenm3	UTSW	8	48,729,204 (GRCm39)	missense	probably benign	0.04
R2234:Tenm3	UTSW	8	48,729,204 (GRCm39)	missense	probably benign	0.04
R2235:Tenm3	UTSW	8	48,729,204 (GRCm39)	missense	probably benign	0.04
R2237:Tenm3	UTSW	8	48,795,372 (GRCm39)	missense	probably damaging	1.00
R2418:Tenm3	UTSW	8	48,729,693 (GRCm39)	missense	possibly damaging	0.87
R2419:Tenm3	UTSW	8	48,729,693 (GRCm39)	missense	possibly damaging	0.87
R2435:Tenm3	UTSW	8	48,740,988 (GRCm39)	missense	probably damaging	1.00
R2483:Tenm3	UTSW	8	48,693,305 (GRCm39)	missense	probably damaging	0.99
R3406:Tenm3	UTSW	8	48,681,590 (GRCm39)	missense	probably damaging	1.00
R3724:Tenm3	UTSW	8	48,730,781 (GRCm39)	missense	probably damaging	0.97
R4009:Tenm3	UTSW	8	48,802,258 (GRCm39)	missense	probably damaging	1.00
R4210:Tenm3	UTSW	8	48,802,439 (GRCm39)	missense	probably damaging	1.00
R4293:Tenm3	UTSW	8	48,848,693 (GRCm39)	missense	probably damaging	1.00
R4656:Tenm3	UTSW	8	48,746,761 (GRCm39)	missense	probably damaging	1.00
R4663:Tenm3	UTSW	8	48,689,005 (GRCm39)	missense	probably damaging	1.00
R4835:Tenm3	UTSW	8	48,766,271 (GRCm39)	critical splice donor site	probably null
R4851:Tenm3	UTSW	8	48,763,656 (GRCm39)	critical splice donor site	probably null
R4867:Tenm3	UTSW	8	48,688,856 (GRCm39)	missense	probably damaging	1.00
R4892:Tenm3	UTSW	8	48,729,896 (GRCm39)	missense	probably damaging	0.99
R4895:Tenm3	UTSW	8	48,754,006 (GRCm39)	missense	probably damaging	1.00
R4962:Tenm3	UTSW	8	48,731,996 (GRCm39)	nonsense	probably null
R4995:Tenm3	UTSW	8	48,682,172 (GRCm39)	missense	possibly damaging	0.87
R4996:Tenm3	UTSW	8	48,688,861 (GRCm39)	missense	probably damaging	0.97
R5091:Tenm3	UTSW	8	48,795,343 (GRCm39)	missense	probably benign	0.14
R5228:Tenm3	UTSW	8	48,689,390 (GRCm39)	missense	probably damaging	1.00
R5253:Tenm3	UTSW	8	48,682,233 (GRCm39)	missense	possibly damaging	0.92
R5260:Tenm3	UTSW	8	48,689,890 (GRCm39)	missense	probably damaging	1.00
R5363:Tenm3	UTSW	8	48,740,866 (GRCm39)	missense	possibly damaging	0.55
R5414:Tenm3	UTSW	8	48,689,390 (GRCm39)	missense	probably damaging	1.00
R5427:Tenm3	UTSW	8	48,689,599 (GRCm39)	missense	probably damaging	1.00
R5431:Tenm3	UTSW	8	48,820,412 (GRCm39)	nonsense	probably null
R5566:Tenm3	UTSW	8	48,732,041 (GRCm39)	missense	probably damaging	1.00
R5579:Tenm3	UTSW	8	48,689,799 (GRCm39)	missense	probably damaging	1.00
R5656:Tenm3	UTSW	8	48,681,797 (GRCm39)	missense	probably damaging	1.00
R5931:Tenm3	UTSW	8	49,099,533 (GRCm39)	missense	probably benign	0.00
R5959:Tenm3	UTSW	8	49,099,482 (GRCm39)	nonsense	probably null
R5965:Tenm3	UTSW	8	48,681,543 (GRCm39)	nonsense	probably null
R6062:Tenm3	UTSW	8	48,796,441 (GRCm39)	missense	possibly damaging	0.46
R6151:Tenm3	UTSW	8	48,848,608 (GRCm39)	missense	probably damaging	1.00
R6157:Tenm3	UTSW	8	48,751,843 (GRCm39)	missense	probably damaging	0.96
R6167:Tenm3	UTSW	8	48,707,657 (GRCm39)	missense	possibly damaging	0.46
R6217:Tenm3	UTSW	8	48,746,700 (GRCm39)	missense	probably damaging	0.99
R6233:Tenm3	UTSW	8	48,870,094 (GRCm39)	missense	probably damaging	1.00
R6270:Tenm3	UTSW	8	48,820,429 (GRCm39)	missense	probably damaging	0.98
R6329:Tenm3	UTSW	8	48,729,884 (GRCm39)	missense	probably damaging	0.99
R6466:Tenm3	UTSW	8	48,689,098 (GRCm39)	missense	probably damaging	0.97
R6515:Tenm3	UTSW	8	48,870,257 (GRCm39)	missense	probably benign
R6516:Tenm3	UTSW	8	48,870,257 (GRCm39)	missense	probably benign
R6747:Tenm3	UTSW	8	48,796,278 (GRCm39)	missense	probably damaging	1.00
R6782:Tenm3	UTSW	8	49,099,291 (GRCm39)	critical splice donor site	probably null
R6788:Tenm3	UTSW	8	49,127,528 (GRCm39)	missense	probably damaging	1.00
R6823:Tenm3	UTSW	8	48,709,872 (GRCm39)	missense	probably damaging	0.99
R6846:Tenm3	UTSW	8	48,729,773 (GRCm39)	missense	probably benign	0.39
R6913:Tenm3	UTSW	8	48,751,972 (GRCm39)	missense	probably damaging	0.99
R6941:Tenm3	UTSW	8	49,127,451 (GRCm39)	missense	probably damaging	0.99
R6950:Tenm3	UTSW	8	48,693,514 (GRCm39)	nonsense	probably null
R6968:Tenm3	UTSW	8	48,689,474 (GRCm39)	missense	probably damaging	1.00
R6970:Tenm3	UTSW	8	48,689,474 (GRCm39)	missense	probably damaging	1.00
R6993:Tenm3	UTSW	8	48,689,474 (GRCm39)	missense	probably damaging	1.00
R7003:Tenm3	UTSW	8	48,693,479 (GRCm39)	missense	probably damaging	1.00
R7125:Tenm3	UTSW	8	49,127,588 (GRCm39)	missense	probably benign	0.00
R7140:Tenm3	UTSW	8	48,745,271 (GRCm39)	missense	probably damaging	1.00
R7222:Tenm3	UTSW	8	48,754,004 (GRCm39)	missense	probably damaging	1.00
R7232:Tenm3	UTSW	8	48,688,970 (GRCm39)	missense	probably damaging	1.00
R7336:Tenm3	UTSW	8	48,689,212 (GRCm39)	missense	possibly damaging	0.93
R7417:Tenm3	UTSW	8	48,689,218 (GRCm39)	missense	probably damaging	1.00
R7526:Tenm3	UTSW	8	48,740,847 (GRCm39)	missense	probably damaging	0.96
R7527:Tenm3	UTSW	8	48,729,635 (GRCm39)	missense	possibly damaging	0.60
R7616:Tenm3	UTSW	8	48,794,084 (GRCm39)	missense	possibly damaging	0.56
R7662:Tenm3	UTSW	8	48,788,762 (GRCm39)	missense	probably benign	0.27
R7802:Tenm3	UTSW	8	48,689,500 (GRCm39)	missense	probably damaging	1.00
R7812:Tenm3	UTSW	8	48,729,335 (GRCm39)	missense	probably benign	0.01
R7843:Tenm3	UTSW	8	48,682,146 (GRCm39)	nonsense	probably null
R7951:Tenm3	UTSW	8	48,763,738 (GRCm39)	missense	possibly damaging	0.86
R8293:Tenm3	UTSW	8	48,820,457 (GRCm39)	missense	possibly damaging	0.91
R8336:Tenm3	UTSW	8	48,746,808 (GRCm39)	missense	probably damaging	1.00
R8351:Tenm3	UTSW	8	48,740,907 (GRCm39)	missense	probably damaging	0.96
R8387:Tenm3	UTSW	8	48,740,883 (GRCm39)	missense	probably damaging	0.98
R8414:Tenm3	UTSW	8	48,746,544 (GRCm39)	missense	probably damaging	1.00
R8451:Tenm3	UTSW	8	48,740,907 (GRCm39)	missense	probably damaging	0.96
R8465:Tenm3	UTSW	8	48,682,216 (GRCm39)	missense	probably damaging	1.00
R8528:Tenm3	UTSW	8	48,795,668 (GRCm39)	missense	probably damaging	1.00
R8717:Tenm3	UTSW	8	48,752,680 (GRCm39)	missense	possibly damaging	0.77
R8734:Tenm3	UTSW	8	48,802,391 (GRCm39)	missense	probably benign	0.16
R8781:Tenm3	UTSW	8	48,795,484 (GRCm39)	frame shift	probably null
R8820:Tenm3	UTSW	8	48,763,759 (GRCm39)	missense	probably damaging	0.96
R8821:Tenm3	UTSW	8	48,729,417 (GRCm39)	missense
R8831:Tenm3	UTSW	8	48,729,417 (GRCm39)	missense
R8853:Tenm3	UTSW	8	48,795,382 (GRCm39)	missense	probably damaging	1.00
R8900:Tenm3	UTSW	8	48,689,437 (GRCm39)	missense	probably damaging	1.00
R8931:Tenm3	UTSW	8	48,688,637 (GRCm39)	missense	probably damaging	1.00
R8933:Tenm3	UTSW	8	48,732,095 (GRCm39)	missense	possibly damaging	0.53
R8989:Tenm3	UTSW	8	48,688,383 (GRCm39)	nonsense	probably null
R8998:Tenm3	UTSW	8	48,729,722 (GRCm39)	missense	probably damaging	1.00
R9008:Tenm3	UTSW	8	48,795,688 (GRCm39)	missense	probably damaging	0.98
R9017:Tenm3	UTSW	8	48,707,668 (GRCm39)	missense	probably damaging	0.99
R9101:Tenm3	UTSW	8	48,745,186 (GRCm39)	missense	probably damaging	1.00
R9108:Tenm3	UTSW	8	48,766,271 (GRCm39)	critical splice donor site	probably null
R9142:Tenm3	UTSW	8	48,788,548 (GRCm39)	missense	unknown
R9231:Tenm3	UTSW	8	48,689,231 (GRCm39)	missense	probably damaging	1.00
R9309:Tenm3	UTSW	8	48,751,972 (GRCm39)	missense	probably damaging	0.99
R9310:Tenm3	UTSW	8	49,008,935 (GRCm39)	unclassified	probably benign
R9336:Tenm3	UTSW	8	48,870,115 (GRCm39)	missense	probably damaging	1.00
R9373:Tenm3	UTSW	8	48,752,690 (GRCm39)	missense	probably damaging	1.00
R9393:Tenm3	UTSW	8	49,127,559 (GRCm39)	missense	probably damaging	0.99
R9509:Tenm3	UTSW	8	48,766,292 (GRCm39)	nonsense	probably null
R9575:Tenm3	UTSW	8	48,688,796 (GRCm39)	missense	possibly damaging	0.94
R9698:Tenm3	UTSW	8	48,689,246 (GRCm39)	missense	probably damaging	1.00
R9722:Tenm3	UTSW	8	48,753,849 (GRCm39)	missense	probably benign	0.00
R9788:Tenm3	UTSW	8	48,788,596 (GRCm39)	missense	probably benign	0.02
X0010:Tenm3	UTSW	8	48,740,864 (GRCm39)	missense	probably damaging	0.98
X0025:Tenm3	UTSW	8	48,689,512 (GRCm39)	missense	probably damaging	1.00
Z1177:Tenm3	UTSW	8	48,729,815 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- GCGGGAAAATCACCATACTATTC -3'
(R):5'- TGTGAATCCGCAACTCGAAG -3'

Sequencing Primer
(F):5'- ACAAGTATTTTCTTGGGCTCTACTAC -3'
(R):5'- TCGAAGAGGAGTGGCATTCTG -3'

Posted On

2019-11-12