Incidental Mutation 'R7748:Chd6'
| ID |
596967 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Chd6
|
| Ensembl Gene |
ENSMUSG00000057133 |
| Gene Name |
chromodomain helicase DNA binding protein 6 |
| Synonyms |
5430439G14Rik, 6330406J24Rik |
| MMRRC Submission |
045804-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.745)
|
| Stock # |
R7748 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
160788898-160950995 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 160808539 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Histidine to Glutamine
at position 1558
(H1558Q)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000042291
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000039782]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000039782
AA Change: H1558Q
PolyPhen 2
Score 0.366 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000042291
Gene: ENSMUSG00000057133
AA Change: H1558Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
86 |
106 |
N/A |
INTRINSIC |
|
low complexity region
|
113 |
143 |
N/A |
INTRINSIC |
|
low complexity region
|
214 |
229 |
N/A |
INTRINSIC |
|
CHROMO
|
289 |
355 |
1.35e-4 |
SMART |
|
CHROMO
|
372 |
430 |
3.48e-7 |
SMART |
|
DEXDc
|
456 |
658 |
1.73e-39 |
SMART |
|
HELICc
|
812 |
896 |
3.84e-23 |
SMART |
|
low complexity region
|
1080 |
1094 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
1108 |
1153 |
4e-23 |
BLAST |
|
SANT
|
1445 |
1504 |
1.51e0 |
SMART |
|
low complexity region
|
1866 |
1875 |
N/A |
INTRINSIC |
|
low complexity region
|
2048 |
2057 |
N/A |
INTRINSIC |
|
low complexity region
|
2130 |
2140 |
N/A |
INTRINSIC |
|
low complexity region
|
2277 |
2290 |
N/A |
INTRINSIC |
|
low complexity region
|
2333 |
2349 |
N/A |
INTRINSIC |
|
low complexity region
|
2437 |
2446 |
N/A |
INTRINSIC |
|
low complexity region
|
2539 |
2563 |
N/A |
INTRINSIC |
|
low complexity region
|
2652 |
2659 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.2%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: This gene encodes a member of the chromodomain/helicase/DNA-binding domain family of chromatin remodeling enzymes. This protein has been found to be specifically involved in transcription initiation and elongation. Homozygous knockout mice exhibit impaired motor coordination. A pseudogene has been identified on chromosome 8. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Nov 2014]
PHENOTYPE: Homozygous null mice display impaired coordination that is not due to muscle weakness or bradykinesia. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 111 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2310057M21Rik |
T |
A |
7: 130,963,521 (GRCm39) |
L103F |
probably benign |
Het |
| 5330417H12Rik |
A |
G |
7: 107,223,765 (GRCm39) |
L103P |
unknown |
Het |
| Actb |
T |
C |
5: 142,890,450 (GRCm39) |
I151V |
probably benign |
Het |
| Adcy6 |
T |
A |
15: 98,502,437 (GRCm39) |
H59L |
probably benign |
Het |
| Adss2 |
G |
C |
1: 177,599,768 (GRCm39) |
S272* |
probably null |
Het |
| Aga |
A |
T |
8: 53,964,840 (GRCm39) |
M1L |
possibly damaging |
Het |
| Ajm1 |
T |
A |
2: 25,468,971 (GRCm39) |
E313D |
possibly damaging |
Het |
| Anxa5 |
G |
A |
3: 36,519,480 (GRCm39) |
T3M |
probably damaging |
Het |
| Arhgap45 |
A |
T |
10: 79,852,766 (GRCm39) |
|
probably benign |
Het |
| Atp6v0a2 |
A |
T |
5: 124,793,560 (GRCm39) |
H639L |
probably benign |
Het |
| BC005537 |
C |
T |
13: 24,987,382 (GRCm39) |
R7W |
possibly damaging |
Het |
| Bcl2l2 |
C |
T |
14: 55,121,836 (GRCm39) |
|
probably benign |
Het |
| Bltp1 |
A |
G |
3: 37,013,484 (GRCm39) |
|
probably null |
Het |
| Bod1l |
A |
C |
5: 41,989,683 (GRCm39) |
S347A |
probably damaging |
Het |
| Calcoco1 |
T |
C |
15: 102,627,996 (GRCm39) |
D46G |
probably damaging |
Het |
| Camk1 |
T |
C |
6: 113,317,289 (GRCm39) |
E60G |
probably damaging |
Het |
| Capza1 |
A |
T |
3: 104,732,721 (GRCm39) |
|
probably null |
Het |
| Ccdc18 |
T |
A |
5: 108,296,907 (GRCm39) |
|
probably null |
Het |
| Cdh20 |
G |
A |
1: 104,869,024 (GRCm39) |
A172T |
probably damaging |
Het |
| Cdk4 |
C |
T |
10: 126,900,298 (GRCm39) |
A65V |
possibly damaging |
Het |
| Cftr |
T |
C |
6: 18,277,888 (GRCm39) |
|
probably null |
Het |
| Chd3 |
T |
C |
11: 69,246,459 (GRCm39) |
M1092V |
probably benign |
Het |
| Chi3l1 |
A |
G |
1: 134,116,966 (GRCm39) |
H318R |
probably benign |
Het |
| Cps1 |
A |
G |
1: 67,178,965 (GRCm39) |
Y59C |
probably damaging |
Het |
| Cyb5r4 |
T |
C |
9: 86,914,434 (GRCm39) |
V111A |
probably damaging |
Het |
| Ddx39b |
G |
A |
17: 35,471,726 (GRCm39) |
V291M |
probably damaging |
Het |
| Dhx57 |
A |
G |
17: 80,572,546 (GRCm39) |
F709S |
probably damaging |
Het |
| Eef1b2 |
A |
T |
1: 63,217,024 (GRCm39) |
K64N |
probably damaging |
Het |
| Eef1ece2 |
A |
T |
16: 20,451,834 (GRCm39) |
D407V |
probably damaging |
Het |
| Fam135a |
A |
G |
1: 24,068,050 (GRCm39) |
S940P |
probably benign |
Het |
| Fam234b |
T |
A |
6: 135,186,349 (GRCm39) |
V119E |
probably damaging |
Het |
| Fbxo46 |
G |
C |
7: 18,870,458 (GRCm39) |
C359S |
probably damaging |
Het |
| Fkbp14 |
C |
A |
6: 54,572,505 (GRCm39) |
|
probably benign |
Het |
| Fmn2 |
T |
A |
1: 174,494,215 (GRCm39) |
V1243E |
probably damaging |
Het |
| Fsbp |
C |
A |
4: 11,579,924 (GRCm39) |
T64K |
probably damaging |
Het |
| Fscb |
A |
T |
12: 64,521,181 (GRCm39) |
M95K |
probably benign |
Het |
| Fyb1 |
T |
G |
15: 6,668,307 (GRCm39) |
V500G |
probably damaging |
Het |
| G2e3 |
A |
G |
12: 51,418,450 (GRCm39) |
N615S |
probably benign |
Het |
| Gart |
T |
C |
16: 91,427,540 (GRCm39) |
D486G |
possibly damaging |
Het |
| Gas2l2 |
T |
A |
11: 83,313,224 (GRCm39) |
D696V |
probably benign |
Het |
| Glmn |
C |
T |
5: 107,710,110 (GRCm39) |
|
probably null |
Het |
| Gm47985 |
A |
T |
1: 151,058,725 (GRCm39) |
D122V |
probably damaging |
Het |
| Gm7168 |
A |
G |
17: 14,168,914 (GRCm39) |
K94E |
probably benign |
Het |
| Gnai2 |
T |
C |
9: 107,492,934 (GRCm39) |
H323R |
|
Het |
| Helz2 |
C |
T |
2: 180,876,324 (GRCm39) |
R1390H |
probably damaging |
Het |
| Igf2bp1 |
T |
C |
11: 95,858,413 (GRCm39) |
M453V |
probably benign |
Het |
| Ighv3-1 |
C |
T |
12: 113,928,270 (GRCm39) |
V30M |
probably damaging |
Het |
| Inpp5a |
A |
T |
7: 139,154,911 (GRCm39) |
R343S |
probably damaging |
Het |
| Itga8 |
T |
A |
2: 12,235,050 (GRCm39) |
I403F |
possibly damaging |
Het |
| Katnip |
A |
T |
7: 125,428,973 (GRCm39) |
M558L |
probably benign |
Het |
| Krt33a |
C |
T |
11: 99,902,428 (GRCm39) |
R404H |
probably benign |
Het |
| Krt34 |
T |
A |
11: 99,929,764 (GRCm39) |
E244V |
probably damaging |
Het |
| Krt42 |
T |
C |
11: 100,157,792 (GRCm39) |
E224G |
probably damaging |
Het |
| Krtap5-2 |
TCCACAGGAACTACAGCCTCCCTTGCAGCCCCCACAGGAACCACAGCCCCCACAGGAACTACA |
TCCACAGGAACTACA |
7: 141,728,845 (GRCm39) |
|
probably benign |
Het |
| Lama1 |
T |
C |
17: 68,057,585 (GRCm39) |
L553P |
|
Het |
| Lcn9 |
T |
A |
2: 25,714,926 (GRCm39) |
*179K |
probably null |
Het |
| Ldaf1 |
A |
T |
7: 119,714,702 (GRCm39) |
I64F |
possibly damaging |
Het |
| Lrrc2 |
T |
G |
9: 110,809,999 (GRCm39) |
M345R |
possibly damaging |
Het |
| Marchf11 |
T |
C |
15: 26,387,916 (GRCm39) |
V257A |
probably damaging |
Het |
| Masp2 |
T |
C |
4: 148,690,163 (GRCm39) |
I224T |
probably benign |
Het |
| Mpz |
A |
T |
1: 170,987,509 (GRCm39) |
|
probably null |
Het |
| Mtr |
C |
T |
13: 12,242,725 (GRCm39) |
A442T |
probably benign |
Het |
| Muc5b |
A |
G |
7: 141,401,542 (GRCm39) |
K596R |
unknown |
Het |
| Myo15a |
T |
G |
11: 60,395,727 (GRCm39) |
F1397C |
|
Het |
| Ncor2 |
T |
C |
5: 125,187,031 (GRCm39) |
I173V |
unknown |
Het |
| Ngly1 |
T |
A |
14: 16,290,820 (GRCm38) |
I434K |
possibly damaging |
Het |
| Notch2 |
A |
G |
3: 98,045,800 (GRCm39) |
H1655R |
possibly damaging |
Het |
| Notum |
C |
T |
11: 120,545,627 (GRCm39) |
A390T |
probably damaging |
Het |
| Or10a3n |
T |
C |
7: 108,493,285 (GRCm39) |
T115A |
probably benign |
Het |
| Or1e22 |
T |
G |
11: 73,376,994 (GRCm39) |
I219L |
probably benign |
Het |
| Pds5a |
T |
A |
5: 65,777,009 (GRCm39) |
I51F |
possibly damaging |
Het |
| Pdzd2 |
C |
A |
15: 12,385,872 (GRCm39) |
R966L |
possibly damaging |
Het |
| Plk3 |
T |
C |
4: 116,988,925 (GRCm39) |
Y278C |
probably damaging |
Het |
| Plxna1 |
C |
G |
6: 89,314,334 (GRCm39) |
|
probably null |
Het |
| Plxna1 |
T |
A |
6: 89,314,335 (GRCm39) |
|
probably null |
Het |
| Ppp4r4 |
G |
A |
12: 103,571,320 (GRCm39) |
|
probably null |
Het |
| Pramel6 |
T |
A |
2: 87,339,043 (GRCm39) |
V81E |
probably damaging |
Het |
| Prdm2 |
T |
C |
4: 142,862,459 (GRCm39) |
E277G |
possibly damaging |
Het |
| Prkg1 |
T |
A |
19: 30,970,491 (GRCm39) |
I222F |
possibly damaging |
Het |
| Proser3 |
A |
T |
7: 30,239,497 (GRCm39) |
S536T |
possibly damaging |
Het |
| Prrt4 |
C |
A |
6: 29,177,190 (GRCm39) |
G193V |
probably damaging |
Het |
| Ptpn21 |
A |
T |
12: 98,655,031 (GRCm39) |
H645Q |
probably benign |
Het |
| Ptprd |
T |
C |
4: 76,017,741 (GRCm39) |
I744V |
probably null |
Het |
| Rad54l2 |
A |
G |
9: 106,596,233 (GRCm39) |
V235A |
possibly damaging |
Het |
| Repin1 |
G |
T |
6: 48,574,279 (GRCm39) |
E403* |
probably null |
Het |
| Rgs22 |
C |
T |
15: 36,122,415 (GRCm39) |
|
probably null |
Het |
| Rtcb |
A |
T |
10: 85,777,832 (GRCm39) |
D447E |
probably benign |
Het |
| Rtn1 |
C |
T |
12: 72,263,700 (GRCm39) |
V744I |
possibly damaging |
Het |
| Scfd1 |
T |
G |
12: 51,436,140 (GRCm39) |
I96M |
probably benign |
Het |
| Serpina3b |
T |
C |
12: 104,096,722 (GRCm39) |
M1T |
probably null |
Het |
| Slc1a4 |
T |
C |
11: 20,282,252 (GRCm39) |
Y74C |
probably damaging |
Het |
| Slc9b2 |
A |
T |
3: 135,031,940 (GRCm39) |
I267F |
possibly damaging |
Het |
| Sorcs2 |
A |
T |
5: 36,386,519 (GRCm39) |
M173K |
possibly damaging |
Het |
| Sparc |
T |
C |
11: 55,289,426 (GRCm39) |
I226V |
probably benign |
Het |
| Spata22 |
T |
G |
11: 73,227,080 (GRCm39) |
I98S |
probably null |
Het |
| Spef2 |
C |
T |
15: 9,653,031 (GRCm39) |
V917M |
probably damaging |
Het |
| Sspo |
C |
A |
6: 48,426,399 (GRCm39) |
C139* |
probably null |
Het |
| Tenm4 |
A |
G |
7: 96,543,909 (GRCm39) |
D2012G |
probably damaging |
Het |
| Tgm5 |
G |
A |
2: 120,883,289 (GRCm39) |
R351C |
probably damaging |
Het |
| Tmem145 |
G |
A |
7: 25,006,753 (GRCm39) |
W82* |
probably null |
Het |
| Topors |
T |
A |
4: 40,262,654 (GRCm39) |
D210V |
probably damaging |
Het |
| Tssk4 |
A |
T |
14: 55,888,569 (GRCm39) |
H146L |
probably damaging |
Het |
| Unc93b1 |
T |
A |
19: 3,985,250 (GRCm39) |
D19E |
unknown |
Het |
| Usp17lc |
A |
G |
7: 103,067,688 (GRCm39) |
T328A |
probably damaging |
Het |
| Utrn |
A |
G |
10: 12,490,252 (GRCm39) |
Y43H |
probably benign |
Het |
| Vmn1r25 |
T |
A |
6: 57,955,549 (GRCm39) |
I247F |
probably damaging |
Het |
| Vmn2r78 |
A |
T |
7: 86,570,343 (GRCm39) |
Q287L |
probably benign |
Het |
| Vps13c |
T |
A |
9: 67,870,371 (GRCm39) |
I3170N |
probably benign |
Het |
| Zfc3h1 |
T |
A |
10: 115,236,720 (GRCm39) |
M398K |
probably benign |
Het |
| Zfp354c |
TCACACTCGGCACA |
TCACA |
11: 50,706,067 (GRCm39) |
|
probably benign |
Het |
| Zfp773 |
T |
C |
7: 7,135,907 (GRCm39) |
R230G |
probably benign |
Het |
|
| Other mutations in Chd6 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00837:Chd6
|
APN |
2 |
160,883,999 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL00899:Chd6
|
APN |
2 |
160,871,218 (GRCm39) |
splice site |
probably benign |
|
|
IGL01104:Chd6
|
APN |
2 |
160,803,847 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01295:Chd6
|
APN |
2 |
160,830,290 (GRCm39) |
splice site |
probably benign |
|
|
IGL01717:Chd6
|
APN |
2 |
160,807,179 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
IGL01795:Chd6
|
APN |
2 |
160,803,294 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01814:Chd6
|
APN |
2 |
160,901,849 (GRCm39) |
missense |
probably benign |
0.25 |
|
IGL02016:Chd6
|
APN |
2 |
160,825,598 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02104:Chd6
|
APN |
2 |
160,819,432 (GRCm39) |
missense |
probably benign |
|
|
IGL02158:Chd6
|
APN |
2 |
160,868,212 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
IGL02313:Chd6
|
APN |
2 |
160,807,595 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02472:Chd6
|
APN |
2 |
160,826,372 (GRCm39) |
splice site |
probably benign |
|
|
IGL02522:Chd6
|
APN |
2 |
160,807,716 (GRCm39) |
missense |
probably benign |
0.30 |
|
IGL02626:Chd6
|
APN |
2 |
160,881,270 (GRCm39) |
splice site |
probably benign |
|
|
IGL02727:Chd6
|
APN |
2 |
160,811,383 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02738:Chd6
|
APN |
2 |
160,807,618 (GRCm39) |
missense |
probably benign |
0.45 |
|
IGL02743:Chd6
|
APN |
2 |
160,802,183 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02800:Chd6
|
APN |
2 |
160,826,552 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02811:Chd6
|
APN |
2 |
160,832,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02850:Chd6
|
APN |
2 |
160,861,536 (GRCm39) |
nonsense |
probably null |
|
|
IGL02979:Chd6
|
APN |
2 |
160,808,090 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
IGL02993:Chd6
|
APN |
2 |
160,894,304 (GRCm39) |
splice site |
probably benign |
|
|
IGL03277:Chd6
|
APN |
2 |
160,824,981 (GRCm39) |
missense |
probably null |
1.00 |
|
IGL03346:Chd6
|
APN |
2 |
160,802,282 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03357:Chd6
|
APN |
2 |
160,859,936 (GRCm39) |
splice site |
probably benign |
|
|
IGL03134:Chd6
|
UTSW |
2 |
160,807,403 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R0106:Chd6
|
UTSW |
2 |
160,809,822 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0106:Chd6
|
UTSW |
2 |
160,809,822 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0212:Chd6
|
UTSW |
2 |
160,894,767 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0363:Chd6
|
UTSW |
2 |
160,856,244 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0399:Chd6
|
UTSW |
2 |
160,894,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0511:Chd6
|
UTSW |
2 |
160,834,111 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0771:Chd6
|
UTSW |
2 |
160,861,500 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1147:Chd6
|
UTSW |
2 |
160,832,191 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1147:Chd6
|
UTSW |
2 |
160,832,191 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1184:Chd6
|
UTSW |
2 |
160,872,722 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1277:Chd6
|
UTSW |
2 |
160,809,735 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1396:Chd6
|
UTSW |
2 |
160,825,023 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1647:Chd6
|
UTSW |
2 |
160,883,978 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1648:Chd6
|
UTSW |
2 |
160,883,978 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1745:Chd6
|
UTSW |
2 |
160,823,587 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1766:Chd6
|
UTSW |
2 |
160,808,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1871:Chd6
|
UTSW |
2 |
160,832,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1928:Chd6
|
UTSW |
2 |
160,809,920 (GRCm39) |
splice site |
probably benign |
|
|
R1973:Chd6
|
UTSW |
2 |
160,808,307 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2200:Chd6
|
UTSW |
2 |
160,825,673 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2340:Chd6
|
UTSW |
2 |
160,807,679 (GRCm39) |
frame shift |
probably null |
|
|
R2341:Chd6
|
UTSW |
2 |
160,807,679 (GRCm39) |
frame shift |
probably null |
|
|
R2519:Chd6
|
UTSW |
2 |
160,871,796 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R2919:Chd6
|
UTSW |
2 |
160,809,800 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R3025:Chd6
|
UTSW |
2 |
160,808,472 (GRCm39) |
small deletion |
probably benign |
|
|
R3426:Chd6
|
UTSW |
2 |
160,832,175 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3427:Chd6
|
UTSW |
2 |
160,832,175 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4042:Chd6
|
UTSW |
2 |
160,830,253 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4273:Chd6
|
UTSW |
2 |
160,803,211 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4360:Chd6
|
UTSW |
2 |
160,791,776 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R4399:Chd6
|
UTSW |
2 |
160,807,238 (GRCm39) |
missense |
probably benign |
|
|
R4458:Chd6
|
UTSW |
2 |
160,871,796 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R4583:Chd6
|
UTSW |
2 |
160,856,114 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4625:Chd6
|
UTSW |
2 |
160,811,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4740:Chd6
|
UTSW |
2 |
160,812,103 (GRCm39) |
missense |
probably benign |
|
|
R4765:Chd6
|
UTSW |
2 |
160,808,164 (GRCm39) |
nonsense |
probably null |
|
|
R4779:Chd6
|
UTSW |
2 |
160,791,477 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4877:Chd6
|
UTSW |
2 |
160,871,219 (GRCm39) |
splice site |
probably benign |
|
|
R5068:Chd6
|
UTSW |
2 |
160,808,289 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R5215:Chd6
|
UTSW |
2 |
160,791,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5275:Chd6
|
UTSW |
2 |
160,811,283 (GRCm39) |
missense |
probably benign |
|
|
R5405:Chd6
|
UTSW |
2 |
160,807,310 (GRCm39) |
missense |
probably benign |
|
|
R5598:Chd6
|
UTSW |
2 |
160,856,032 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5693:Chd6
|
UTSW |
2 |
160,807,185 (GRCm39) |
missense |
probably benign |
|
|
R5697:Chd6
|
UTSW |
2 |
160,859,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5715:Chd6
|
UTSW |
2 |
160,791,798 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5759:Chd6
|
UTSW |
2 |
160,825,682 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R5761:Chd6
|
UTSW |
2 |
160,798,999 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5761:Chd6
|
UTSW |
2 |
160,798,998 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5954:Chd6
|
UTSW |
2 |
160,807,747 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6025:Chd6
|
UTSW |
2 |
160,807,502 (GRCm39) |
missense |
probably benign |
|
|
R6104:Chd6
|
UTSW |
2 |
160,856,052 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6247:Chd6
|
UTSW |
2 |
160,791,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6393:Chd6
|
UTSW |
2 |
160,821,407 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6452:Chd6
|
UTSW |
2 |
160,807,418 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R6468:Chd6
|
UTSW |
2 |
160,854,987 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6784:Chd6
|
UTSW |
2 |
160,808,174 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6803:Chd6
|
UTSW |
2 |
160,802,279 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R6869:Chd6
|
UTSW |
2 |
160,807,650 (GRCm39) |
missense |
probably benign |
|
|
R6895:Chd6
|
UTSW |
2 |
160,830,260 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6925:Chd6
|
UTSW |
2 |
160,855,047 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7061:Chd6
|
UTSW |
2 |
160,867,885 (GRCm39) |
nonsense |
probably null |
|
|
R7064:Chd6
|
UTSW |
2 |
160,791,983 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7248:Chd6
|
UTSW |
2 |
160,803,199 (GRCm39) |
nonsense |
probably null |
|
|
R7287:Chd6
|
UTSW |
2 |
160,850,312 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7431:Chd6
|
UTSW |
2 |
160,868,248 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7486:Chd6
|
UTSW |
2 |
160,791,923 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7509:Chd6
|
UTSW |
2 |
160,855,074 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7699:Chd6
|
UTSW |
2 |
160,867,863 (GRCm39) |
missense |
probably benign |
0.13 |
|
R7785:Chd6
|
UTSW |
2 |
160,812,095 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R8002:Chd6
|
UTSW |
2 |
160,832,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8261:Chd6
|
UTSW |
2 |
160,799,002 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8317:Chd6
|
UTSW |
2 |
160,832,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8388:Chd6
|
UTSW |
2 |
160,861,571 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8865:Chd6
|
UTSW |
2 |
160,862,989 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8867:Chd6
|
UTSW |
2 |
160,862,989 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8996:Chd6
|
UTSW |
2 |
160,823,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9091:Chd6
|
UTSW |
2 |
160,871,793 (GRCm39) |
nonsense |
probably null |
|
|
R9270:Chd6
|
UTSW |
2 |
160,871,793 (GRCm39) |
nonsense |
probably null |
|
|
R9310:Chd6
|
UTSW |
2 |
160,881,181 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9367:Chd6
|
UTSW |
2 |
160,871,784 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9438:Chd6
|
UTSW |
2 |
160,799,078 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9756:Chd6
|
UTSW |
2 |
160,802,259 (GRCm39) |
missense |
probably benign |
|
|
Z1088:Chd6
|
UTSW |
2 |
160,808,408 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGGCAACAGAGACTTCCAGG -3'
(R):5'- CACAGCATTGGTTTAAGTGGGAAC -3'
Sequencing Primer
(F):5'- AACAGAGACTTCCAGGTGCCTG -3'
(R):5'- GGAACCATGGCTTGTTTCTATTTTAC -3'
|
| Posted On |
2019-11-26 |
Incidental Mutation