Mutagenetix > Incidental Mutation

Incidental Mutation 'R7748:Vps13c'

597014

Institutional Source

Beutler Lab

Gene Symbol

Vps13c

Ensembl Gene

ENSMUSG00000035284

Gene Name

vacuolar protein sorting 13C

Synonyms

C230055H22Rik

MMRRC Submission

045804-MU

Accession Numbers

Genbank: NM_177184; MGI: 2444207

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R7748 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

67840396-67995638 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 67963089 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Asparagine at position 3170 (I3170N)

Ref Sequence

ENSEMBL: ENSMUSP00000077040 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000077879]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000077879
AA Change: I3170N

PolyPhen 2 Score 0.028 (Sensitivity: 0.95; Specificity: 0.81)

SMART Domains

Protein: ENSMUSP00000077040
Gene: ENSMUSG00000035284
AA Change: I3170N

Domain	Start	End	E-Value	Type
Pfam:Chorein_N	3	117	1.3e-39	PFAM
low complexity region	151	165	N/A	INTRINSIC
Pfam:VPS13	182	414	7.9e-70	PFAM
coiled coil region	422	443	N/A	INTRINSIC
low complexity region	479	490	N/A	INTRINSIC
Pfam:VPS13_mid_rpt	611	832	7.8e-71	PFAM
low complexity region	867	885	N/A	INTRINSIC
low complexity region	1020	1036	N/A	INTRINSIC
low complexity region	1112	1123	N/A	INTRINSIC
Pfam:VPS13_mid_rpt	1172	1369	2.1e-14	PFAM
low complexity region	1552	1573	N/A	INTRINSIC
Pfam:VPS13_mid_rpt	1685	1883	2.8e-13	PFAM
Blast:INB	2128	2403	2e-48	BLAST
Pfam:SHR-BD	2759	3013	9.9e-32	PFAM
Pfam:VPS13_C	3317	3495	5.7e-65	PFAM
Pfam:ATG_C	3498	3588	7.9e-12	PFAM

Predicted Effect

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.8%
20x: 99.2%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the vacuolar protein sorting-associated 13 gene family. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2010]

Allele List at MGI

All alleles(13) : Targeted, other(2) Gene trapped(11)

Other mutations in this stock

Total: 111 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2310057M21Rik	T	A	7: 131,361,792 (GRCm38)	L103F	probably benign	Het
4932438A13Rik	A	G	3: 36,959,335 (GRCm38)		probably null	Het
5330417H12Rik	A	G	7: 107,624,558 (GRCm38)	L103P	unknown	Het
Actb	T	C	5: 142,904,695 (GRCm38)	I151V	probably benign	Het
Adcy6	T	A	15: 98,604,556 (GRCm38)	H59L	probably benign	Het
Adss	G	C	1: 177,772,202 (GRCm38)	S272*	probably null	Het
Aga	A	T	8: 53,511,805 (GRCm38)	M1L	possibly damaging	Het
Anxa5	G	A	3: 36,465,331 (GRCm38)	T3M	probably damaging	Het
Arhgap45	A	T	10: 80,016,932 (GRCm38)		probably benign	Het
Atp6v0a2	A	T	5: 124,716,496 (GRCm38)	H639L	probably benign	Het
BC005537	C	T	13: 24,803,399 (GRCm38)	R7W	possibly damaging	Het
Bcl2l2	C	T	14: 54,884,379 (GRCm38)		probably benign	Het
Bod1l	A	C	5: 41,832,340 (GRCm38)	S347A	probably damaging	Het
Calcoco1	T	C	15: 102,719,561 (GRCm38)	D46G	probably damaging	Het
Camk1	T	C	6: 113,340,328 (GRCm38)	E60G	probably damaging	Het
Capza1	A	T	3: 104,825,405 (GRCm38)		probably null	Het
Ccdc18	T	A	5: 108,149,041 (GRCm38)		probably null	Het
Cdh20	G	A	1: 104,941,299 (GRCm38)	A172T	probably damaging	Het
Cdk4	C	T	10: 127,064,429 (GRCm38)	A65V	possibly damaging	Het
Cftr	T	C	6: 18,277,889 (GRCm38)		probably null	Het
Chd3	T	C	11: 69,355,633 (GRCm38)	M1092V	probably benign	Het
Chd6	A	T	2: 160,966,619 (GRCm38)	H1558Q	probably benign	Het
Chil1	A	G	1: 134,189,228 (GRCm38)	H318R	probably benign	Het
Cps1	A	G	1: 67,139,806 (GRCm38)	Y59C	probably damaging	Het
Cyb5r4	T	C	9: 87,032,381 (GRCm38)	V111A	probably damaging	Het
D430042O09Rik	A	T	7: 125,829,801 (GRCm38)	M558L	probably benign	Het
Ddx39b	G	A	17: 35,252,750 (GRCm38)	V291M	probably damaging	Het
Dhx57	A	G	17: 80,265,117 (GRCm38)	F709S	probably damaging	Het
Eef1b2	A	T	1: 63,177,865 (GRCm38)	K64N	probably damaging	Het
Fam135a	A	G	1: 24,028,969 (GRCm38)	S940P	probably benign	Het
Fam234b	T	A	6: 135,209,351 (GRCm38)	V119E	probably damaging	Het
Fbxo46	G	C	7: 19,136,533 (GRCm38)	C359S	probably damaging	Het
Fkbp14	C	A	6: 54,595,520 (GRCm38)		probably benign	Het
Fmn2	T	A	1: 174,666,649 (GRCm38)	V1243E	probably damaging	Het
Fsbp	C	A	4: 11,579,924 (GRCm38)	T64K	probably damaging	Het
Fscb	A	T	12: 64,474,407 (GRCm38)	M95K	probably benign	Het
Fyb	T	G	15: 6,638,826 (GRCm38)	V500G	probably damaging	Het
G2e3	A	G	12: 51,371,667 (GRCm38)	N615S	probably benign	Het
Gart	T	C	16: 91,630,652 (GRCm38)	D486G	possibly damaging	Het
Gas2l2	T	A	11: 83,422,398 (GRCm38)	D696V	probably benign	Het
Glmn	C	T	5: 107,562,244 (GRCm38)		probably null	Het
Gm47985	A	T	1: 151,182,974 (GRCm38)	D122V	probably damaging	Het
Gm49333	A	T	16: 20,633,084 (GRCm38)	D407V	probably damaging	Het
Gm7168	A	G	17: 13,948,652 (GRCm38)	K94E	probably benign	Het
Gm996	T	A	2: 25,578,959 (GRCm38)	E313D	possibly damaging	Het
Gnai2	T	C	9: 107,615,735 (GRCm38)	H323R		Het
Helz2	C	T	2: 181,234,531 (GRCm38)	R1390H	probably damaging	Het
Igf2bp1	T	C	11: 95,967,587 (GRCm38)	M453V	probably benign	Het
Ighv3-1	C	T	12: 113,964,650 (GRCm38)	V30M	probably damaging	Het
Inpp5a	A	T	7: 139,574,995 (GRCm38)	R343S	probably damaging	Het
Itga8	T	A	2: 12,230,239 (GRCm38)	I403F	possibly damaging	Het
Krt33a	C	T	11: 100,011,602 (GRCm38)	R404H	probably benign	Het
Krt34	T	A	11: 100,038,938 (GRCm38)	E244V	probably damaging	Het
Krt42	T	C	11: 100,266,966 (GRCm38)	E224G	probably damaging	Het
Krtap5-2	TCCACAGGAACTACAGCCTCCCTTGCAGCCCCCACAGGAACCACAGCCCCCACAGGAACTACA	TCCACAGGAACTACA	7: 142,175,108 (GRCm38)		probably benign	Het
Lama1	T	C	17: 67,750,590 (GRCm38)	L553P		Het
Lcn9	T	A	2: 25,824,914 (GRCm38)	*179K	probably null	Het
Lrrc2	T	G	9: 110,980,931 (GRCm38)	M345R	possibly damaging	Het
March11	T	C	15: 26,387,830 (GRCm38)	V257A	probably damaging	Het
Masp2	T	C	4: 148,605,706 (GRCm38)	I224T	probably benign	Het
Mpz	A	T	1: 171,159,940 (GRCm38)		probably null	Het
Mtr	C	T	13: 12,227,839 (GRCm38)	A442T	probably benign	Het
Muc5b	A	G	7: 141,847,805 (GRCm38)	K596R	unknown	Het
Myo15	T	G	11: 60,504,901 (GRCm38)	F1397C		Het
Ncor2	T	C	5: 125,109,967 (GRCm38)	I173V	unknown	Het
Ngly1	T	A	14: 16,290,820 (GRCm38)	I434K	possibly damaging	Het
Notch2	A	G	3: 98,138,484 (GRCm38)	H1655R	possibly damaging	Het
Notum	C	T	11: 120,654,801 (GRCm38)	A390T	probably damaging	Het
Olfr381	T	G	11: 73,486,168 (GRCm38)	I219L	probably benign	Het
Olfr519	T	C	7: 108,894,078 (GRCm38)	T115A	probably benign	Het
Pds5a	T	A	5: 65,619,666 (GRCm38)	I51F	possibly damaging	Het
Pdzd2	C	A	15: 12,385,786 (GRCm38)	R966L	possibly damaging	Het
Plk3	T	C	4: 117,131,728 (GRCm38)	Y278C	probably damaging	Het
Plxna1	T	A	6: 89,337,353 (GRCm38)		probably null	Het
Plxna1	C	G	6: 89,337,352 (GRCm38)		probably null	Het
Ppp4r4	G	A	12: 103,605,061 (GRCm38)		probably null	Het
Pramel6	T	A	2: 87,508,699 (GRCm38)	V81E	probably damaging	Het
Prdm2	T	C	4: 143,135,889 (GRCm38)	E277G	possibly damaging	Het
Prkg1	T	A	19: 30,993,091 (GRCm38)	I222F	possibly damaging	Het
Proser3	A	T	7: 30,540,072 (GRCm38)	S536T	possibly damaging	Het
Prrt4	C	A	6: 29,177,191 (GRCm38)	G193V	probably damaging	Het
Ptpn21	A	T	12: 98,688,772 (GRCm38)	H645Q	probably benign	Het
Ptprd	T	C	4: 76,099,504 (GRCm38)	I744V	probably null	Het
Rad54l2	A	G	9: 106,719,034 (GRCm38)	V235A	possibly damaging	Het
Repin1	G	T	6: 48,597,345 (GRCm38)	E403*	probably null	Het
Rgs22	C	T	15: 36,122,269 (GRCm38)		probably null	Het
Rtcb	A	T	10: 85,941,968 (GRCm38)	D447E	probably benign	Het
Rtn1	C	T	12: 72,216,926 (GRCm38)	V744I	possibly damaging	Het
Scfd1	T	G	12: 51,389,357 (GRCm38)	I96M	probably benign	Het
Serpina3b	T	C	12: 104,130,463 (GRCm38)	M1T	probably null	Het
Slc1a4	T	C	11: 20,332,252 (GRCm38)	Y74C	probably damaging	Het
Slc9b2	A	T	3: 135,326,179 (GRCm38)	I267F	possibly damaging	Het
Sorcs2	A	T	5: 36,229,175 (GRCm38)	M173K	possibly damaging	Het
Sparc	T	C	11: 55,398,600 (GRCm38)	I226V	probably benign	Het
Spata22	T	G	11: 73,336,254 (GRCm38)	I98S	probably null	Het
Spef2	C	T	15: 9,652,945 (GRCm38)	V917M	probably damaging	Het
Sspo	C	A	6: 48,449,465 (GRCm38)	C139*	probably null	Het
Tenm4	A	G	7: 96,894,702 (GRCm38)	D2012G	probably damaging	Het
Tgm5	G	A	2: 121,052,808 (GRCm38)	R351C	probably damaging	Het
Tmem145	G	A	7: 25,307,328 (GRCm38)	W82*	probably null	Het
Tmem159	A	T	7: 120,115,479 (GRCm38)	I64F	possibly damaging	Het
Topors	T	A	4: 40,262,654 (GRCm38)	D210V	probably damaging	Het
Tssk4	A	T	14: 55,651,112 (GRCm38)	H146L	probably damaging	Het
Unc93b1	T	A	19: 3,935,250 (GRCm38)	D19E	unknown	Het
Usp17lc	A	G	7: 103,418,481 (GRCm38)	T328A	probably damaging	Het
Utrn	A	G	10: 12,614,508 (GRCm38)	Y43H	probably benign	Het
Vmn1r25	T	A	6: 57,978,564 (GRCm38)	I247F	probably damaging	Het
Vmn2r78	A	T	7: 86,921,135 (GRCm38)	Q287L	probably benign	Het
Zfc3h1	T	A	10: 115,400,815 (GRCm38)	M398K	probably benign	Het
Zfp354c	TCACACTCGGCACA	TCACA	11: 50,815,240 (GRCm38)		probably benign	Het
Zfp773	T	C	7: 7,132,908 (GRCm38)	R230G	probably benign	Het

Other mutations in Vps13c

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00159:Vps13c	APN	9	67,945,999 (GRCm38)	missense	probably benign	0.20
IGL00336:Vps13c	APN	9	67,945,942 (GRCm38)	missense	probably benign	0.01
IGL00418:Vps13c	APN	9	67,876,262 (GRCm38)	missense	probably damaging	1.00
IGL00481:Vps13c	APN	9	67,860,865 (GRCm38)	missense	probably damaging	1.00
IGL00491:Vps13c	APN	9	67,893,136 (GRCm38)	missense	probably damaging	1.00
IGL00558:Vps13c	APN	9	67,937,857 (GRCm38)	missense	possibly damaging	0.52
IGL00811:Vps13c	APN	9	67,948,181 (GRCm38)	missense	probably damaging	0.99
IGL01011:Vps13c	APN	9	67,926,955 (GRCm38)	missense	probably damaging	0.98
IGL01094:Vps13c	APN	9	67,886,284 (GRCm38)	missense	probably damaging	1.00
IGL01330:Vps13c	APN	9	67,964,108 (GRCm38)	missense	probably damaging	1.00
IGL01402:Vps13c	APN	9	67,913,204 (GRCm38)	critical splice acceptor site	probably null
IGL01404:Vps13c	APN	9	67,913,204 (GRCm38)	critical splice acceptor site	probably null
IGL01470:Vps13c	APN	9	67,912,927 (GRCm38)	splice site	probably benign
IGL01615:Vps13c	APN	9	67,955,781 (GRCm38)	missense	probably benign	0.01
IGL01694:Vps13c	APN	9	67,895,349 (GRCm38)	missense	probably damaging	1.00
IGL01752:Vps13c	APN	9	67,948,228 (GRCm38)	missense	probably damaging	1.00
IGL01810:Vps13c	APN	9	67,955,780 (GRCm38)	missense	probably benign
IGL01954:Vps13c	APN	9	67,969,298 (GRCm38)	missense	probably damaging	0.98
IGL01978:Vps13c	APN	9	67,930,643 (GRCm38)	missense	probably benign	0.03
IGL01998:Vps13c	APN	9	67,955,068 (GRCm38)	splice site	probably null
IGL02201:Vps13c	APN	9	67,967,136 (GRCm38)	missense	probably damaging	1.00
IGL02205:Vps13c	APN	9	67,883,454 (GRCm38)	missense	probably damaging	1.00
IGL02303:Vps13c	APN	9	67,945,481 (GRCm38)	splice site	probably benign
IGL02322:Vps13c	APN	9	67,937,901 (GRCm38)	missense	probably benign	0.02
IGL02456:Vps13c	APN	9	67,952,976 (GRCm38)	missense	probably damaging	1.00
IGL02474:Vps13c	APN	9	67,937,876 (GRCm38)	missense	probably benign	0.00
IGL02547:Vps13c	APN	9	67,908,019 (GRCm38)	missense	possibly damaging	0.83
IGL02640:Vps13c	APN	9	67,886,248 (GRCm38)	splice site	probably benign
IGL02673:Vps13c	APN	9	67,878,098 (GRCm38)	missense	probably damaging	1.00
IGL02721:Vps13c	APN	9	67,964,149 (GRCm38)	splice site	probably benign
IGL02834:Vps13c	APN	9	67,937,855 (GRCm38)	missense	probably benign
IGL02838:Vps13c	APN	9	67,975,851 (GRCm38)	missense	probably damaging	1.00
IGL03136:Vps13c	APN	9	67,950,310 (GRCm38)	missense	probably damaging	1.00
IGL03137:Vps13c	APN	9	67,890,380 (GRCm38)	missense	probably damaging	1.00
IGL03214:Vps13c	APN	9	67,897,195 (GRCm38)	missense	probably null	0.81
IGL03240:Vps13c	APN	9	67,955,047 (GRCm38)	missense	probably benign
IGL03303:Vps13c	APN	9	67,934,504 (GRCm38)	missense	probably benign	0.27
IGL03336:Vps13c	APN	9	67,951,642 (GRCm38)	missense	possibly damaging	0.76
IGL03366:Vps13c	APN	9	67,946,026 (GRCm38)	missense	probably benign	0.00
Derivative	UTSW	9	67,930,622 (GRCm38)	missense	possibly damaging	0.79
diversion	UTSW	9	67,910,233 (GRCm38)	missense	possibly damaging	0.93
introversion	UTSW	9	67,944,046 (GRCm38)	missense	probably damaging	0.98
Inversion	UTSW	9	67,902,839 (GRCm38)	critical splice acceptor site	probably null
subversion	UTSW	9	67,908,052 (GRCm38)	missense	probably damaging	1.00
Transversion	UTSW	9	67,934,501 (GRCm38)	missense	probably damaging	0.98
3-1:Vps13c	UTSW	9	67,936,373 (GRCm38)	missense	probably benign	0.00
IGL02991:Vps13c	UTSW	9	67,913,877 (GRCm38)	missense	probably damaging	1.00
PIT4802001:Vps13c	UTSW	9	67,937,786 (GRCm38)	missense	probably damaging	1.00
R0008:Vps13c	UTSW	9	67,919,262 (GRCm38)	missense	probably benign
R0206:Vps13c	UTSW	9	67,939,162 (GRCm38)	splice site	probably benign
R0288:Vps13c	UTSW	9	67,927,366 (GRCm38)	missense	probably damaging	0.99
R0324:Vps13c	UTSW	9	67,964,309 (GRCm38)	missense	possibly damaging	0.95
R0347:Vps13c	UTSW	9	67,910,233 (GRCm38)	missense	possibly damaging	0.93
R0374:Vps13c	UTSW	9	67,886,246 (GRCm38)	splice site	probably benign
R0388:Vps13c	UTSW	9	67,922,915 (GRCm38)	splice site	probably benign
R0409:Vps13c	UTSW	9	67,951,644 (GRCm38)	missense	probably benign	0.00
R0440:Vps13c	UTSW	9	67,972,861 (GRCm38)	missense	probably damaging	1.00
R0513:Vps13c	UTSW	9	67,930,735 (GRCm38)	missense	probably benign	0.02
R0520:Vps13c	UTSW	9	67,945,851 (GRCm38)	missense	possibly damaging	0.88
R0569:Vps13c	UTSW	9	67,973,719 (GRCm38)	missense	probably damaging	0.98
R0601:Vps13c	UTSW	9	67,927,472 (GRCm38)	missense	probably benign	0.12
R0659:Vps13c	UTSW	9	67,920,935 (GRCm38)	missense	probably benign	0.11
R0667:Vps13c	UTSW	9	67,951,573 (GRCm38)	nonsense	probably null
R0670:Vps13c	UTSW	9	67,925,857 (GRCm38)	missense	probably benign	0.35
R0698:Vps13c	UTSW	9	67,889,723 (GRCm38)	missense	probably benign	0.45
R0729:Vps13c	UTSW	9	67,961,649 (GRCm38)	missense	probably damaging	1.00
R0781:Vps13c	UTSW	9	67,972,003 (GRCm38)	missense	probably damaging	1.00
R0811:Vps13c	UTSW	9	67,934,476 (GRCm38)	missense	probably benign	0.06
R0812:Vps13c	UTSW	9	67,934,476 (GRCm38)	missense	probably benign	0.06
R0839:Vps13c	UTSW	9	67,898,738 (GRCm38)	missense	probably benign
R1373:Vps13c	UTSW	9	67,927,511 (GRCm38)	missense	probably damaging	0.99
R1396:Vps13c	UTSW	9	67,955,022 (GRCm38)	missense	probably benign	0.00
R1499:Vps13c	UTSW	9	67,957,505 (GRCm38)	missense	probably benign	0.00
R1556:Vps13c	UTSW	9	67,930,711 (GRCm38)	missense	probably damaging	0.98
R1560:Vps13c	UTSW	9	67,936,463 (GRCm38)	critical splice donor site	probably null
R1584:Vps13c	UTSW	9	67,893,112 (GRCm38)	missense	possibly damaging	0.74
R1654:Vps13c	UTSW	9	67,951,687 (GRCm38)	missense	probably damaging	1.00
R1674:Vps13c	UTSW	9	67,853,703 (GRCm38)	nonsense	probably null
R1676:Vps13c	UTSW	9	67,926,962 (GRCm38)	missense	probably benign	0.20
R1695:Vps13c	UTSW	9	67,972,075 (GRCm38)	nonsense	probably null
R1710:Vps13c	UTSW	9	67,911,529 (GRCm38)	missense	probably benign	0.00
R1769:Vps13c	UTSW	9	67,965,721 (GRCm38)	missense	probably benign	0.00
R1775:Vps13c	UTSW	9	67,881,447 (GRCm38)	missense	probably damaging	1.00
R1795:Vps13c	UTSW	9	67,893,985 (GRCm38)	nonsense	probably null
R1799:Vps13c	UTSW	9	67,944,117 (GRCm38)	missense	probably damaging	0.98
R1835:Vps13c	UTSW	9	67,993,013 (GRCm38)	missense	probably benign	0.08
R1848:Vps13c	UTSW	9	67,936,340 (GRCm38)	missense	probably benign
R1903:Vps13c	UTSW	9	67,894,052 (GRCm38)	missense	probably damaging	1.00
R1944:Vps13c	UTSW	9	67,886,276 (GRCm38)	missense	probably damaging	1.00
R1945:Vps13c	UTSW	9	67,886,276 (GRCm38)	missense	probably damaging	1.00
R1951:Vps13c	UTSW	9	67,973,759 (GRCm38)	critical splice donor site	probably null
R1993:Vps13c	UTSW	9	67,975,856 (GRCm38)	missense	probably damaging	1.00
R2023:Vps13c	UTSW	9	67,936,285 (GRCm38)	splice site	probably benign
R2059:Vps13c	UTSW	9	67,860,833 (GRCm38)	missense	probably damaging	1.00
R2086:Vps13c	UTSW	9	67,950,289 (GRCm38)	missense	probably benign	0.29
R2120:Vps13c	UTSW	9	67,919,334 (GRCm38)	missense	possibly damaging	0.92
R2249:Vps13c	UTSW	9	67,988,053 (GRCm38)	critical splice donor site	probably null
R2257:Vps13c	UTSW	9	67,952,946 (GRCm38)	missense	possibly damaging	0.87
R2258:Vps13c	UTSW	9	67,953,860 (GRCm38)	missense	probably benign	0.01
R2259:Vps13c	UTSW	9	67,953,860 (GRCm38)	missense	probably benign	0.01
R2260:Vps13c	UTSW	9	67,953,860 (GRCm38)	missense	probably benign	0.01
R2265:Vps13c	UTSW	9	67,920,947 (GRCm38)	missense	possibly damaging	0.82
R2266:Vps13c	UTSW	9	67,920,947 (GRCm38)	missense	possibly damaging	0.82
R2269:Vps13c	UTSW	9	67,920,947 (GRCm38)	missense	possibly damaging	0.82
R2278:Vps13c	UTSW	9	67,939,072 (GRCm38)	missense	probably benign
R2306:Vps13c	UTSW	9	67,987,993 (GRCm38)	missense	probably damaging	0.99
R2327:Vps13c	UTSW	9	67,913,820 (GRCm38)	missense	probably damaging	0.98
R2349:Vps13c	UTSW	9	67,957,526 (GRCm38)	missense	possibly damaging	0.89
R2483:Vps13c	UTSW	9	67,975,907 (GRCm38)	critical splice donor site	probably null
R3031:Vps13c	UTSW	9	67,923,770 (GRCm38)	missense	probably benign	0.00
R3623:Vps13c	UTSW	9	67,975,907 (GRCm38)	critical splice donor site	probably null
R3870:Vps13c	UTSW	9	67,884,726 (GRCm38)	missense	probably benign	0.00
R4173:Vps13c	UTSW	9	67,936,313 (GRCm38)	missense	probably benign	0.00
R4445:Vps13c	UTSW	9	67,982,495 (GRCm38)	splice site	probably null
R4491:Vps13c	UTSW	9	67,910,193 (GRCm38)	missense	probably benign
R4505:Vps13c	UTSW	9	67,939,034 (GRCm38)	missense	probably benign	0.02
R4574:Vps13c	UTSW	9	67,951,683 (GRCm38)	missense	probably damaging	1.00
R4691:Vps13c	UTSW	9	67,952,935 (GRCm38)	missense	possibly damaging	0.95
R4766:Vps13c	UTSW	9	67,878,224 (GRCm38)	splice site	probably null
R4771:Vps13c	UTSW	9	67,929,539 (GRCm38)	missense	probably benign
R4801:Vps13c	UTSW	9	67,964,282 (GRCm38)	missense	probably damaging	1.00
R4802:Vps13c	UTSW	9	67,964,282 (GRCm38)	missense	probably damaging	1.00
R4962:Vps13c	UTSW	9	67,873,891 (GRCm38)	missense	probably damaging	1.00
R4995:Vps13c	UTSW	9	67,919,321 (GRCm38)	missense	probably benign	0.00
R5010:Vps13c	UTSW	9	67,916,379 (GRCm38)	missense	probably benign	0.19
R5183:Vps13c	UTSW	9	67,908,052 (GRCm38)	missense	probably damaging	1.00
R5226:Vps13c	UTSW	9	67,945,553 (GRCm38)	missense	probably benign	0.17
R5297:Vps13c	UTSW	9	67,878,131 (GRCm38)	missense	probably damaging	1.00
R5456:Vps13c	UTSW	9	67,927,447 (GRCm38)	missense	possibly damaging	0.53
R5494:Vps13c	UTSW	9	67,948,146 (GRCm38)	missense	probably benign	0.00
R5521:Vps13c	UTSW	9	67,951,439 (GRCm38)	missense	probably benign	0.08
R5524:Vps13c	UTSW	9	67,957,556 (GRCm38)	missense	probably damaging	1.00
R5685:Vps13c	UTSW	9	67,963,173 (GRCm38)	missense	possibly damaging	0.64
R5731:Vps13c	UTSW	9	67,895,379 (GRCm38)	missense	probably damaging	1.00
R5812:Vps13c	UTSW	9	67,982,495 (GRCm38)	splice site	probably benign
R5867:Vps13c	UTSW	9	67,982,622 (GRCm38)	splice site	probably null
R5893:Vps13c	UTSW	9	67,902,839 (GRCm38)	critical splice acceptor site	probably null
R5902:Vps13c	UTSW	9	67,934,447 (GRCm38)	missense	probably benign	0.00
R5957:Vps13c	UTSW	9	67,954,971 (GRCm38)	missense	probably damaging	1.00
R6076:Vps13c	UTSW	9	67,911,602 (GRCm38)	missense	probably damaging	1.00
R6187:Vps13c	UTSW	9	67,915,657 (GRCm38)	missense	probably damaging	1.00
R6268:Vps13c	UTSW	9	67,951,449 (GRCm38)	missense	probably benign	0.10
R6547:Vps13c	UTSW	9	67,973,365 (GRCm38)	missense	probably damaging	1.00
R6716:Vps13c	UTSW	9	67,951,467 (GRCm38)	missense	probably benign	0.00
R6837:Vps13c	UTSW	9	67,910,222 (GRCm38)	missense	probably benign
R6919:Vps13c	UTSW	9	67,927,452 (GRCm38)	missense	probably damaging	0.97
R7039:Vps13c	UTSW	9	67,937,763 (GRCm38)	missense	probably damaging	1.00
R7058:Vps13c	UTSW	9	67,923,828 (GRCm38)	missense	probably benign	0.39
R7082:Vps13c	UTSW	9	67,883,453 (GRCm38)	missense	probably damaging	1.00
R7195:Vps13c	UTSW	9	67,945,825 (GRCm38)	missense	possibly damaging	0.95
R7244:Vps13c	UTSW	9	67,889,804 (GRCm38)	missense	probably benign	0.00
R7300:Vps13c	UTSW	9	67,940,544 (GRCm38)	missense	probably benign	0.20
R7314:Vps13c	UTSW	9	67,943,340 (GRCm38)	splice site	probably null
R7352:Vps13c	UTSW	9	67,840,446 (GRCm38)	missense	possibly damaging	0.94
R7368:Vps13c	UTSW	9	67,914,073 (GRCm38)	missense	probably benign	0.23
R7411:Vps13c	UTSW	9	67,972,001 (GRCm38)	missense	probably damaging	0.98
R7497:Vps13c	UTSW	9	67,840,479 (GRCm38)	missense	probably damaging	1.00
R7516:Vps13c	UTSW	9	67,955,007 (GRCm38)	missense	possibly damaging	0.89
R7638:Vps13c	UTSW	9	67,945,509 (GRCm38)	missense	probably damaging	1.00
R7732:Vps13c	UTSW	9	67,940,516 (GRCm38)	missense	probably damaging	0.97
R7779:Vps13c	UTSW	9	67,881,422 (GRCm38)	missense	probably damaging	1.00
R7788:Vps13c	UTSW	9	67,940,483 (GRCm38)	missense	probably benign	0.01
R7894:Vps13c	UTSW	9	67,926,983 (GRCm38)	missense	probably damaging	0.99
R8163:Vps13c	UTSW	9	67,950,438 (GRCm38)	missense	probably benign	0.08
R8165:Vps13c	UTSW	9	67,858,790 (GRCm38)	missense	probably benign	0.00
R8202:Vps13c	UTSW	9	67,944,046 (GRCm38)	missense	probably damaging	0.98
R8235:Vps13c	UTSW	9	67,955,781 (GRCm38)	missense	probably benign	0.01
R8235:Vps13c	UTSW	9	67,927,396 (GRCm38)	missense	probably damaging	1.00
R8253:Vps13c	UTSW	9	67,943,488 (GRCm38)	nonsense	probably null
R8261:Vps13c	UTSW	9	67,954,980 (GRCm38)	missense	probably damaging	1.00
R8348:Vps13c	UTSW	9	67,879,103 (GRCm38)	missense	possibly damaging	0.79
R8547:Vps13c	UTSW	9	67,945,566 (GRCm38)	missense	probably damaging	1.00
R8734:Vps13c	UTSW	9	67,973,403 (GRCm38)	missense	probably damaging	1.00
R8806:Vps13c	UTSW	9	67,945,828 (GRCm38)	missense	probably damaging	1.00
R8807:Vps13c	UTSW	9	67,858,840 (GRCm38)	missense	probably damaging	0.99
R8813:Vps13c	UTSW	9	67,871,284 (GRCm38)	missense	probably damaging	1.00
R8883:Vps13c	UTSW	9	67,948,197 (GRCm38)	missense	probably benign	0.10
R8885:Vps13c	UTSW	9	67,943,454 (GRCm38)	missense	probably benign
R8899:Vps13c	UTSW	9	67,934,501 (GRCm38)	missense	probably damaging	0.98
R8970:Vps13c	UTSW	9	67,945,521 (GRCm38)	missense	probably benign	0.11
R9007:Vps13c	UTSW	9	67,937,724 (GRCm38)	missense	probably benign	0.00
R9026:Vps13c	UTSW	9	67,954,581 (GRCm38)	missense	probably damaging	1.00
R9029:Vps13c	UTSW	9	67,948,147 (GRCm38)	missense	probably damaging	0.98
R9057:Vps13c	UTSW	9	67,920,927 (GRCm38)	missense	probably benign	0.00
R9105:Vps13c	UTSW	9	67,870,799 (GRCm38)	intron	probably benign
R9130:Vps13c	UTSW	9	67,929,523 (GRCm38)	missense	probably damaging	1.00
R9286:Vps13c	UTSW	9	67,972,921 (GRCm38)	missense	probably benign	0.00
R9338:Vps13c	UTSW	9	67,951,695 (GRCm38)	missense	probably damaging	1.00
R9432:Vps13c	UTSW	9	67,922,855 (GRCm38)	missense	probably benign	0.02
R9460:Vps13c	UTSW	9	67,930,622 (GRCm38)	missense	possibly damaging	0.79
R9464:Vps13c	UTSW	9	67,951,392 (GRCm38)	missense	probably damaging	1.00
R9561:Vps13c	UTSW	9	67,965,512 (GRCm38)	missense	probably damaging	1.00
R9609:Vps13c	UTSW	9	67,934,549 (GRCm38)	missense	probably damaging	1.00
R9622:Vps13c	UTSW	9	67,949,433 (GRCm38)	missense	probably damaging	1.00
R9665:Vps13c	UTSW	9	67,955,743 (GRCm38)	nonsense	probably null
R9731:Vps13c	UTSW	9	67,919,244 (GRCm38)	missense	probably benign
R9763:Vps13c	UTSW	9	67,911,578 (GRCm38)	missense	probably benign	0.00
R9774:Vps13c	UTSW	9	67,884,591 (GRCm38)	missense	possibly damaging	0.85
R9798:Vps13c	UTSW	9	67,919,364 (GRCm38)	missense	probably damaging	1.00
U24488:Vps13c	UTSW	9	67,905,916 (GRCm38)	missense	probably benign	0.13
X0021:Vps13c	UTSW	9	67,937,781 (GRCm38)	missense	probably damaging	0.99
X0058:Vps13c	UTSW	9	67,927,419 (GRCm38)	missense	probably damaging	1.00
X0065:Vps13c	UTSW	9	67,873,863 (GRCm38)	missense	probably damaging	1.00
Z1088:Vps13c	UTSW	9	67,913,975 (GRCm38)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- AGTGGCCTTCATGAGACAGG -3'
(R):5'- AGGCCTTATGCACACTACAC -3'

Sequencing Primer
(F):5'- CTTCATGAGACAGGGACATGACC -3'
(R):5'- TTTTCAAGCTGCACCCCAGAG -3'

Posted On

2019-11-26