Mutagenetix > Incidental Mutation

Incidental Mutation 'R7748:Arhgap45'

597020

Institutional Source

Beutler Lab

Gene Symbol

Arhgap45

Ensembl Gene

ENSMUSG00000035697

Gene Name

Rho GTPase activating protein 45

Synonyms

6330406L22Rik, Hmha1

MMRRC Submission

045804-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R7748 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

80016653-80031472 bp(+) (GRCm38)

Type of Mutation

unclassified

DNA Base Change (assembly)

A to T at 80016932 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000128121 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000043311] [ENSMUST00000043866] [ENSMUST00000099501] [ENSMUST00000105373] [ENSMUST00000132517] [ENSMUST00000171637]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000043311

SMART Domains

Protein: ENSMUSP00000041019
Gene: ENSMUSG00000035697

Domain	Start	End	E-Value	Type
low complexity region	142	153	N/A	INTRINSIC
FCH	157	244	4.14e-17	SMART
low complexity region	255	269	N/A	INTRINSIC
low complexity region	309	324	N/A	INTRINSIC
low complexity region	330	345	N/A	INTRINSIC
low complexity region	527	536	N/A	INTRINSIC
C1	582	628	3.15e-8	SMART
RhoGAP	653	852	2.73e-73	SMART
low complexity region	856	869	N/A	INTRINSIC
Blast:RhoGAP	876	999	1e-21	BLAST

Predicted Effect

probably benign
Transcript: ENSMUST00000043866

SMART Domains

Protein: ENSMUSP00000043090
Gene: ENSMUSG00000035722

Domain	Start	End	E-Value	Type
transmembrane domain	23	42	N/A	INTRINSIC
Pfam:ABC2_membrane_3	515	747	1.1e-17	PFAM
AAA	830	1011	4.97e-12	SMART
low complexity region	1136	1147	N/A	INTRINSIC
transmembrane domain	1241	1263	N/A	INTRINSIC
low complexity region	1299	1309	N/A	INTRINSIC
low complexity region	1374	1390	N/A	INTRINSIC
Pfam:ABC2_membrane_3	1427	1764	9e-43	PFAM
AAA	1833	2018	7.2e-9	SMART
low complexity region	2120	2135	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000099501

SMART Domains

Protein: ENSMUSP00000097100
Gene: ENSMUSG00000035697

Domain	Start	End	E-Value	Type
low complexity region	258	269	N/A	INTRINSIC
FCH	273	360	4.14e-17	SMART
low complexity region	371	385	N/A	INTRINSIC
low complexity region	425	440	N/A	INTRINSIC
low complexity region	446	461	N/A	INTRINSIC
low complexity region	643	652	N/A	INTRINSIC
C1	698	744	3.15e-8	SMART
RhoGAP	769	968	2.73e-73	SMART
low complexity region	972	985	N/A	INTRINSIC
Blast:RhoGAP	992	1115	1e-21	BLAST

Predicted Effect

probably benign
Transcript: ENSMUST00000105373

SMART Domains

Protein: ENSMUSP00000101012
Gene: ENSMUSG00000035697

Domain	Start	End	E-Value	Type
low complexity region	269	280	N/A	INTRINSIC
FCH	284	371	4.14e-17	SMART
low complexity region	382	396	N/A	INTRINSIC
low complexity region	436	451	N/A	INTRINSIC
low complexity region	457	472	N/A	INTRINSIC
low complexity region	654	663	N/A	INTRINSIC
C1	709	755	3.15e-8	SMART
RhoGAP	780	979	2.73e-73	SMART
low complexity region	983	996	N/A	INTRINSIC
Blast:RhoGAP	1003	1126	1e-21	BLAST

Predicted Effect

probably benign
Transcript: ENSMUST00000132517

SMART Domains

Protein: ENSMUSP00000115111
Gene: ENSMUSG00000035722

Domain	Start	End	E-Value	Type
transmembrane domain	23	42	N/A	INTRINSIC
Pfam:ABC2_membrane_3	515	747	1.1e-17	PFAM
AAA	830	1011	4.97e-12	SMART
low complexity region	1136	1147	N/A	INTRINSIC
transmembrane domain	1241	1263	N/A	INTRINSIC
low complexity region	1299	1309	N/A	INTRINSIC
low complexity region	1374	1390	N/A	INTRINSIC
Pfam:ABC2_membrane_3	1427	1764	9e-43	PFAM
AAA	1833	2018	7.2e-9	SMART
low complexity region	2120	2135	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000171637

SMART Domains

Protein: ENSMUSP00000128121
Gene: ENSMUSG00000035722

Domain	Start	End	E-Value	Type
transmembrane domain	23	42	N/A	INTRINSIC
Pfam:ABC2_membrane_3	517	747	2.8e-19	PFAM
AAA	830	1011	4.97e-12	SMART
low complexity region	1136	1147	N/A	INTRINSIC
transmembrane domain	1249	1271	N/A	INTRINSIC
low complexity region	1307	1317	N/A	INTRINSIC
low complexity region	1382	1398	N/A	INTRINSIC
Pfam:ABC2_membrane_3	1426	1772	3.9e-47	PFAM
AAA	1841	2026	7.2e-9	SMART
low complexity region	2128	2143	N/A	INTRINSIC

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.8%
20x: 99.2%

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 111 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2310057M21Rik	T	A	7: 131,361,792 (GRCm38)	L103F	probably benign	Het
4932438A13Rik	A	G	3: 36,959,335 (GRCm38)		probably null	Het
5330417H12Rik	A	G	7: 107,624,558 (GRCm38)	L103P	unknown	Het
Actb	T	C	5: 142,904,695 (GRCm38)	I151V	probably benign	Het
Adcy6	T	A	15: 98,604,556 (GRCm38)	H59L	probably benign	Het
Adss	G	C	1: 177,772,202 (GRCm38)	S272*	probably null	Het
Aga	A	T	8: 53,511,805 (GRCm38)	M1L	possibly damaging	Het
Anxa5	G	A	3: 36,465,331 (GRCm38)	T3M	probably damaging	Het
Atp6v0a2	A	T	5: 124,716,496 (GRCm38)	H639L	probably benign	Het
BC005537	C	T	13: 24,803,399 (GRCm38)	R7W	possibly damaging	Het
Bcl2l2	C	T	14: 54,884,379 (GRCm38)		probably benign	Het
Bod1l	A	C	5: 41,832,340 (GRCm38)	S347A	probably damaging	Het
Calcoco1	T	C	15: 102,719,561 (GRCm38)	D46G	probably damaging	Het
Camk1	T	C	6: 113,340,328 (GRCm38)	E60G	probably damaging	Het
Capza1	A	T	3: 104,825,405 (GRCm38)		probably null	Het
Ccdc18	T	A	5: 108,149,041 (GRCm38)		probably null	Het
Cdh20	G	A	1: 104,941,299 (GRCm38)	A172T	probably damaging	Het
Cdk4	C	T	10: 127,064,429 (GRCm38)	A65V	possibly damaging	Het
Cftr	T	C	6: 18,277,889 (GRCm38)		probably null	Het
Chd3	T	C	11: 69,355,633 (GRCm38)	M1092V	probably benign	Het
Chd6	A	T	2: 160,966,619 (GRCm38)	H1558Q	probably benign	Het
Chil1	A	G	1: 134,189,228 (GRCm38)	H318R	probably benign	Het
Cps1	A	G	1: 67,139,806 (GRCm38)	Y59C	probably damaging	Het
Cyb5r4	T	C	9: 87,032,381 (GRCm38)	V111A	probably damaging	Het
D430042O09Rik	A	T	7: 125,829,801 (GRCm38)	M558L	probably benign	Het
Ddx39b	G	A	17: 35,252,750 (GRCm38)	V291M	probably damaging	Het
Dhx57	A	G	17: 80,265,117 (GRCm38)	F709S	probably damaging	Het
Eef1b2	A	T	1: 63,177,865 (GRCm38)	K64N	probably damaging	Het
Fam135a	A	G	1: 24,028,969 (GRCm38)	S940P	probably benign	Het
Fam234b	T	A	6: 135,209,351 (GRCm38)	V119E	probably damaging	Het
Fbxo46	G	C	7: 19,136,533 (GRCm38)	C359S	probably damaging	Het
Fkbp14	C	A	6: 54,595,520 (GRCm38)		probably benign	Het
Fmn2	T	A	1: 174,666,649 (GRCm38)	V1243E	probably damaging	Het
Fsbp	C	A	4: 11,579,924 (GRCm38)	T64K	probably damaging	Het
Fscb	A	T	12: 64,474,407 (GRCm38)	M95K	probably benign	Het
Fyb	T	G	15: 6,638,826 (GRCm38)	V500G	probably damaging	Het
G2e3	A	G	12: 51,371,667 (GRCm38)	N615S	probably benign	Het
Gart	T	C	16: 91,630,652 (GRCm38)	D486G	possibly damaging	Het
Gas2l2	T	A	11: 83,422,398 (GRCm38)	D696V	probably benign	Het
Glmn	C	T	5: 107,562,244 (GRCm38)		probably null	Het
Gm47985	A	T	1: 151,182,974 (GRCm38)	D122V	probably damaging	Het
Gm49333	A	T	16: 20,633,084 (GRCm38)	D407V	probably damaging	Het
Gm7168	A	G	17: 13,948,652 (GRCm38)	K94E	probably benign	Het
Gm996	T	A	2: 25,578,959 (GRCm38)	E313D	possibly damaging	Het
Gnai2	T	C	9: 107,615,735 (GRCm38)	H323R		Het
Helz2	C	T	2: 181,234,531 (GRCm38)	R1390H	probably damaging	Het
Igf2bp1	T	C	11: 95,967,587 (GRCm38)	M453V	probably benign	Het
Ighv3-1	C	T	12: 113,964,650 (GRCm38)	V30M	probably damaging	Het
Inpp5a	A	T	7: 139,574,995 (GRCm38)	R343S	probably damaging	Het
Itga8	T	A	2: 12,230,239 (GRCm38)	I403F	possibly damaging	Het
Krt33a	C	T	11: 100,011,602 (GRCm38)	R404H	probably benign	Het
Krt34	T	A	11: 100,038,938 (GRCm38)	E244V	probably damaging	Het
Krt42	T	C	11: 100,266,966 (GRCm38)	E224G	probably damaging	Het
Krtap5-2	TCCACAGGAACTACAGCCTCCCTTGCAGCCCCCACAGGAACCACAGCCCCCACAGGAACTACA	TCCACAGGAACTACA	7: 142,175,108 (GRCm38)		probably benign	Het
Lama1	T	C	17: 67,750,590 (GRCm38)	L553P		Het
Lcn9	T	A	2: 25,824,914 (GRCm38)	*179K	probably null	Het
Lrrc2	T	G	9: 110,980,931 (GRCm38)	M345R	possibly damaging	Het
March11	T	C	15: 26,387,830 (GRCm38)	V257A	probably damaging	Het
Masp2	T	C	4: 148,605,706 (GRCm38)	I224T	probably benign	Het
Mpz	A	T	1: 171,159,940 (GRCm38)		probably null	Het
Mtr	C	T	13: 12,227,839 (GRCm38)	A442T	probably benign	Het
Muc5b	A	G	7: 141,847,805 (GRCm38)	K596R	unknown	Het
Myo15	T	G	11: 60,504,901 (GRCm38)	F1397C		Het
Ncor2	T	C	5: 125,109,967 (GRCm38)	I173V	unknown	Het
Ngly1	T	A	14: 16,290,820 (GRCm38)	I434K	possibly damaging	Het
Notch2	A	G	3: 98,138,484 (GRCm38)	H1655R	possibly damaging	Het
Notum	C	T	11: 120,654,801 (GRCm38)	A390T	probably damaging	Het
Olfr381	T	G	11: 73,486,168 (GRCm38)	I219L	probably benign	Het
Olfr519	T	C	7: 108,894,078 (GRCm38)	T115A	probably benign	Het
Pds5a	T	A	5: 65,619,666 (GRCm38)	I51F	possibly damaging	Het
Pdzd2	C	A	15: 12,385,786 (GRCm38)	R966L	possibly damaging	Het
Plk3	T	C	4: 117,131,728 (GRCm38)	Y278C	probably damaging	Het
Plxna1	T	A	6: 89,337,353 (GRCm38)		probably null	Het
Plxna1	C	G	6: 89,337,352 (GRCm38)		probably null	Het
Ppp4r4	G	A	12: 103,605,061 (GRCm38)		probably null	Het
Pramel6	T	A	2: 87,508,699 (GRCm38)	V81E	probably damaging	Het
Prdm2	T	C	4: 143,135,889 (GRCm38)	E277G	possibly damaging	Het
Prkg1	T	A	19: 30,993,091 (GRCm38)	I222F	possibly damaging	Het
Proser3	A	T	7: 30,540,072 (GRCm38)	S536T	possibly damaging	Het
Prrt4	C	A	6: 29,177,191 (GRCm38)	G193V	probably damaging	Het
Ptpn21	A	T	12: 98,688,772 (GRCm38)	H645Q	probably benign	Het
Ptprd	T	C	4: 76,099,504 (GRCm38)	I744V	probably null	Het
Rad54l2	A	G	9: 106,719,034 (GRCm38)	V235A	possibly damaging	Het
Repin1	G	T	6: 48,597,345 (GRCm38)	E403*	probably null	Het
Rgs22	C	T	15: 36,122,269 (GRCm38)		probably null	Het
Rtcb	A	T	10: 85,941,968 (GRCm38)	D447E	probably benign	Het
Rtn1	C	T	12: 72,216,926 (GRCm38)	V744I	possibly damaging	Het
Scfd1	T	G	12: 51,389,357 (GRCm38)	I96M	probably benign	Het
Serpina3b	T	C	12: 104,130,463 (GRCm38)	M1T	probably null	Het
Slc1a4	T	C	11: 20,332,252 (GRCm38)	Y74C	probably damaging	Het
Slc9b2	A	T	3: 135,326,179 (GRCm38)	I267F	possibly damaging	Het
Sorcs2	A	T	5: 36,229,175 (GRCm38)	M173K	possibly damaging	Het
Sparc	T	C	11: 55,398,600 (GRCm38)	I226V	probably benign	Het
Spata22	T	G	11: 73,336,254 (GRCm38)	I98S	probably null	Het
Spef2	C	T	15: 9,652,945 (GRCm38)	V917M	probably damaging	Het
Sspo	C	A	6: 48,449,465 (GRCm38)	C139*	probably null	Het
Tenm4	A	G	7: 96,894,702 (GRCm38)	D2012G	probably damaging	Het
Tgm5	G	A	2: 121,052,808 (GRCm38)	R351C	probably damaging	Het
Tmem145	G	A	7: 25,307,328 (GRCm38)	W82*	probably null	Het
Tmem159	A	T	7: 120,115,479 (GRCm38)	I64F	possibly damaging	Het
Topors	T	A	4: 40,262,654 (GRCm38)	D210V	probably damaging	Het
Tssk4	A	T	14: 55,651,112 (GRCm38)	H146L	probably damaging	Het
Unc93b1	T	A	19: 3,935,250 (GRCm38)	D19E	unknown	Het
Usp17lc	A	G	7: 103,418,481 (GRCm38)	T328A	probably damaging	Het
Utrn	A	G	10: 12,614,508 (GRCm38)	Y43H	probably benign	Het
Vmn1r25	T	A	6: 57,978,564 (GRCm38)	I247F	probably damaging	Het
Vmn2r78	A	T	7: 86,921,135 (GRCm38)	Q287L	probably benign	Het
Vps13c	T	A	9: 67,963,089 (GRCm38)	I3170N	probably benign	Het
Zfc3h1	T	A	10: 115,400,815 (GRCm38)	M398K	probably benign	Het
Zfp354c	TCACACTCGGCACA	TCACA	11: 50,815,240 (GRCm38)		probably benign	Het
Zfp773	T	C	7: 7,132,908 (GRCm38)	R230G	probably benign	Het

Other mutations in Arhgap45

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01360:Arhgap45	APN	10	80,028,648 (GRCm38)	splice site	probably benign
IGL01414:Arhgap45	APN	10	80,027,104 (GRCm38)	missense	probably damaging	1.00
IGL01505:Arhgap45	APN	10	80,026,542 (GRCm38)	missense	probably benign	0.10
IGL02203:Arhgap45	APN	10	80,027,553 (GRCm38)	nonsense	probably null
IGL02557:Arhgap45	APN	10	80,021,638 (GRCm38)	missense	probably damaging	1.00
IGL02858:Arhgap45	APN	10	80,017,934 (GRCm38)	missense	probably benign	0.20
IGL03292:Arhgap45	APN	10	80,020,969 (GRCm38)	missense	probably benign	0.04
IGL03352:Arhgap45	APN	10	80,030,751 (GRCm38)	missense	probably damaging	0.96
Celt	UTSW	10	80,020,818 (GRCm38)	missense	probably damaging	1.00
celtic	UTSW	10	80,027,589 (GRCm38)	nonsense	probably null
druid	UTSW	10	80,026,347 (GRCm38)	critical splice donor site	probably null
Mistletoe	UTSW	10	80,027,102 (GRCm38)	nonsense	probably null
Roman	UTSW	10	80,027,597 (GRCm38)	missense	probably damaging	1.00
stonehenge	UTSW	10	80,025,482 (GRCm38)	missense	possibly damaging	0.81
IGL03048:Arhgap45	UTSW	10	80,017,017 (GRCm38)	missense	probably damaging	0.99
PIT4677001:Arhgap45	UTSW	10	80,020,749 (GRCm38)	missense	probably benign
R0532:Arhgap45	UTSW	10	80,022,083 (GRCm38)	missense	possibly damaging	0.92
R1233:Arhgap45	UTSW	10	80,027,582 (GRCm38)	missense	probably damaging	1.00
R1579:Arhgap45	UTSW	10	80,028,977 (GRCm38)	missense	probably damaging	1.00
R1666:Arhgap45	UTSW	10	80,028,750 (GRCm38)	missense	possibly damaging	0.82
R1668:Arhgap45	UTSW	10	80,028,750 (GRCm38)	missense	possibly damaging	0.82
R1688:Arhgap45	UTSW	10	80,029,095 (GRCm38)	missense	probably damaging	1.00
R1710:Arhgap45	UTSW	10	80,018,098 (GRCm38)	nonsense	probably null
R1902:Arhgap45	UTSW	10	80,025,466 (GRCm38)	missense	probably damaging	0.99
R1912:Arhgap45	UTSW	10	80,020,690 (GRCm38)	missense	probably benign	0.08
R1935:Arhgap45	UTSW	10	80,030,954 (GRCm38)	missense	probably damaging	1.00
R1936:Arhgap45	UTSW	10	80,030,954 (GRCm38)	missense	probably damaging	1.00
R1955:Arhgap45	UTSW	10	80,026,492 (GRCm38)	missense	probably benign	0.15
R1968:Arhgap45	UTSW	10	80,027,702 (GRCm38)	missense	probably damaging	1.00
R1977:Arhgap45	UTSW	10	80,020,818 (GRCm38)	missense	probably damaging	1.00
R1986:Arhgap45	UTSW	10	80,020,696 (GRCm38)	missense	probably damaging	1.00
R2074:Arhgap45	UTSW	10	80,027,180 (GRCm38)	missense	probably damaging	1.00
R2081:Arhgap45	UTSW	10	80,027,674 (GRCm38)	missense	probably damaging	1.00
R2162:Arhgap45	UTSW	10	80,016,979 (GRCm38)	start codon destroyed	probably null	0.02
R2937:Arhgap45	UTSW	10	80,029,002 (GRCm38)	missense	probably damaging	1.00
R2938:Arhgap45	UTSW	10	80,029,002 (GRCm38)	missense	probably damaging	1.00
R3081:Arhgap45	UTSW	10	80,026,447 (GRCm38)	missense	probably damaging	1.00
R4695:Arhgap45	UTSW	10	80,025,530 (GRCm38)	missense	probably damaging	1.00
R4736:Arhgap45	UTSW	10	80,026,172 (GRCm38)	missense	probably damaging	1.00
R4758:Arhgap45	UTSW	10	80,030,293 (GRCm38)	missense	probably benign	0.00
R4860:Arhgap45	UTSW	10	80,027,066 (GRCm38)	missense	probably damaging	1.00
R4860:Arhgap45	UTSW	10	80,027,066 (GRCm38)	missense	probably damaging	1.00
R4934:Arhgap45	UTSW	10	80,020,957 (GRCm38)	missense	probably damaging	1.00
R4943:Arhgap45	UTSW	10	80,026,503 (GRCm38)	missense	probably benign	0.00
R5102:Arhgap45	UTSW	10	80,021,428 (GRCm38)	missense	probably benign	0.01
R5128:Arhgap45	UTSW	10	80,030,959 (GRCm38)	missense	probably benign	0.16
R5667:Arhgap45	UTSW	10	80,025,476 (GRCm38)	missense	probably damaging	1.00
R5671:Arhgap45	UTSW	10	80,025,476 (GRCm38)	missense	probably damaging	1.00
R5920:Arhgap45	UTSW	10	80,029,131 (GRCm38)	missense	possibly damaging	0.87
R5998:Arhgap45	UTSW	10	80,030,950 (GRCm38)	missense	probably damaging	0.99
R6276:Arhgap45	UTSW	10	80,026,234 (GRCm38)	missense	probably benign	0.25
R6675:Arhgap45	UTSW	10	80,018,104 (GRCm38)	missense	probably null	0.98
R6738:Arhgap45	UTSW	10	80,027,597 (GRCm38)	missense	probably damaging	1.00
R6783:Arhgap45	UTSW	10	80,017,864 (GRCm38)	missense	possibly damaging	0.92
R6863:Arhgap45	UTSW	10	80,017,782 (GRCm38)	missense	probably benign	0.03
R6978:Arhgap45	UTSW	10	80,021,848 (GRCm38)	missense	probably benign	0.00
R7089:Arhgap45	UTSW	10	80,026,347 (GRCm38)	critical splice donor site	probably null
R7215:Arhgap45	UTSW	10	80,025,482 (GRCm38)	missense	possibly damaging	0.81
R7307:Arhgap45	UTSW	10	80,029,182 (GRCm38)	missense	probably benign	0.14
R7308:Arhgap45	UTSW	10	80,026,558 (GRCm38)	critical splice donor site	probably null
R7480:Arhgap45	UTSW	10	80,027,102 (GRCm38)	nonsense	probably null
R7481:Arhgap45	UTSW	10	80,022,300 (GRCm38)	missense	possibly damaging	0.80
R7649:Arhgap45	UTSW	10	80,031,001 (GRCm38)	missense	probably benign	0.00
R7652:Arhgap45	UTSW	10	80,028,838 (GRCm38)	missense	probably benign	0.01
R7883:Arhgap45	UTSW	10	80,027,589 (GRCm38)	nonsense	probably null
R8121:Arhgap45	UTSW	10	80,018,075 (GRCm38)	missense	probably damaging	0.99
R8169:Arhgap45	UTSW	10	80,027,872 (GRCm38)	missense	probably damaging	1.00
R8170:Arhgap45	UTSW	10	80,027,872 (GRCm38)	missense	probably damaging	1.00
R8175:Arhgap45	UTSW	10	80,027,872 (GRCm38)	missense	probably damaging	1.00
R8178:Arhgap45	UTSW	10	80,027,872 (GRCm38)	missense	probably damaging	1.00
R8186:Arhgap45	UTSW	10	80,027,872 (GRCm38)	missense	probably damaging	1.00
R8187:Arhgap45	UTSW	10	80,027,872 (GRCm38)	missense	probably damaging	1.00
R8687:Arhgap45	UTSW	10	80,016,787 (GRCm38)	unclassified	probably benign
R8866:Arhgap45	UTSW	10	80,017,916 (GRCm38)	missense	probably damaging	1.00
R8905:Arhgap45	UTSW	10	80,019,736 (GRCm38)	missense	probably benign	0.00
R9299:Arhgap45	UTSW	10	80,026,731 (GRCm38)	missense	possibly damaging	0.82
R9412:Arhgap45	UTSW	10	80,019,730 (GRCm38)	start codon destroyed	probably null	0.66
R9579:Arhgap45	UTSW	10	80,018,009 (GRCm38)	missense	probably benign
R9629:Arhgap45	UTSW	10	80,027,860 (GRCm38)	missense	probably damaging	1.00
R9710:Arhgap45	UTSW	10	80,021,801 (GRCm38)	missense	probably damaging	0.99
X0023:Arhgap45	UTSW	10	80,030,800 (GRCm38)	missense	probably damaging	0.98
X0063:Arhgap45	UTSW	10	80,030,356 (GRCm38)	missense	possibly damaging	0.51
Z1176:Arhgap45	UTSW	10	80,029,052 (GRCm38)	missense	probably damaging	0.99
Z1176:Arhgap45	UTSW	10	80,025,536 (GRCm38)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- TGAGCAATGTGGTCCAGAG -3'
(R):5'- TCCCTACCTACCGTAATGCG -3'

Sequencing Primer
(F):5'- CAATGTGGTCCAGAGACAGCC -3'
(R):5'- TAATGCGGCCTCCTAGGTTCAG -3'

Posted On

2019-11-26