Mutagenetix > Incidental Mutation

Incidental Mutation 'R7750:Muc5ac'

597154

Institutional Source

Beutler Lab

Gene Symbol

Muc5ac

Ensembl Gene

ENSMUSG00000037974

Gene Name

mucin 5, subtypes A and C, tracheobronchial/gastric

Synonyms

MGM, 2210005L13Rik

MMRRC Submission

045806-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R7750 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

141788972-141819231 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

G to C at 141809303 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Glycine to Alanine at position 2117 (G2117A)

Ref Sequence

ENSEMBL: ENSMUSP00000122353 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000041924] [ENSMUST00000155534] [ENSMUST00000163321]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000041924

SMART Domains

Protein: ENSMUSP00000039699
Gene: ENSMUSG00000037974

Domain	Start	End	E-Value	Type
signal peptide	1	27	N/A	INTRINSIC
VWD	69	226	4.19e-30	SMART
C8	258	334	1.34e-11	SMART
Pfam:TIL	337	393	1.6e-14	PFAM
VWC	395	462	8.6e-18	SMART
VWD	421	585	1.55e-33	SMART
C8	622	696	8.42e-36	SMART
Pfam:TIL	702	759	6.1e-9	PFAM
VWC	761	825	6.75e-1	SMART
VWC	863	905	4.06e-1	SMART
VWD	890	1050	1.51e-45	SMART
C8	1086	1160	2.78e-36	SMART
low complexity region	1315	1330	N/A	INTRINSIC
low complexity region	1333	1366	N/A	INTRINSIC
low complexity region	1371	1387	N/A	INTRINSIC
Pfam:Mucin2_WxxW	1394	1482	2.3e-25	PFAM
low complexity region	1521	1532	N/A	INTRINSIC
low complexity region	1536	1563	N/A	INTRINSIC
low complexity region	1578	1595	N/A	INTRINSIC
Pfam:Mucin2_WxxW	1604	1692	2.2e-27	PFAM
Pfam:Mucin2_WxxW	1765	1857	8.6e-27	PFAM
low complexity region	1875	1895	N/A	INTRINSIC
low complexity region	1949	1968	N/A	INTRINSIC
VWD	2030	2199	4.17e-48	SMART
C8	2242	2311	3.95e-9	SMART
VWC	2376	2439	1.04e-11	SMART
VWC	2479	2543	9.31e-5	SMART
CT	2625	2711	3.43e-32	SMART
low complexity region	2720	2733	N/A	INTRINSIC

Predicted Effect

unknown
Transcript: ENSMUST00000155534
AA Change: G2117A

SMART Domains

Protein: ENSMUSP00000122353
Gene: ENSMUSG00000037974
AA Change: G2117A

Domain	Start	End	E-Value	Type
signal peptide	1	27	N/A	INTRINSIC
VWD	69	226	4.19e-30	SMART
C8	258	334	1.34e-11	SMART
Pfam:TIL	337	393	9.6e-15	PFAM
VWC	395	437	3.54e-1	SMART
VWD	422	586	2.35e-33	SMART
C8	623	697	8.42e-36	SMART
Pfam:TIL	703	760	3.6e-9	PFAM
VWC	762	826	6.75e-1	SMART
VWC	864	906	4.06e-1	SMART
VWD	891	1051	1.51e-45	SMART
C8	1087	1161	2.78e-36	SMART
low complexity region	1316	1331	N/A	INTRINSIC
low complexity region	1334	1367	N/A	INTRINSIC
low complexity region	1372	1388	N/A	INTRINSIC
Pfam:Mucin2_WxxW	1395	1483	1.3e-25	PFAM
low complexity region	1522	1533	N/A	INTRINSIC
low complexity region	1537	1564	N/A	INTRINSIC
low complexity region	1579	1596	N/A	INTRINSIC
Pfam:Mucin2_WxxW	1605	1693	1.3e-27	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000163321

SMART Domains

Protein: ENSMUSP00000131681
Gene: ENSMUSG00000037974

Domain	Start	End	E-Value	Type
signal peptide	1	27	N/A	INTRINSIC
VWD	69	226	4.19e-30	SMART
C8	258	334	1.34e-11	SMART
Pfam:TIL	337	393	7.9e-15	PFAM
VWC	395	462	8.6e-18	SMART
VWD	421	585	1.55e-33	SMART
C8	622	696	8.42e-36	SMART
Pfam:TIL	702	759	1.9e-9	PFAM
VWC	761	825	6.75e-1	SMART
VWC	863	905	4.06e-1	SMART
VWD	890	1050	1.51e-45	SMART
C8	1086	1160	2.78e-36	SMART
low complexity region	1315	1330	N/A	INTRINSIC
low complexity region	1333	1366	N/A	INTRINSIC
low complexity region	1371	1387	N/A	INTRINSIC
Pfam:Mucin2_WxxW	1394	1481	1.1e-23	PFAM
low complexity region	1521	1532	N/A	INTRINSIC
low complexity region	1536	1563	N/A	INTRINSIC
low complexity region	1578	1595	N/A	INTRINSIC
Pfam:Mucin2_WxxW	1604	1691	1.1e-25	PFAM
Pfam:Mucin2_WxxW	1765	1856	6.3e-24	PFAM
low complexity region	1875	1895	N/A	INTRINSIC
low complexity region	1949	1968	N/A	INTRINSIC
VWD	2030	2199	4.17e-48	SMART
C8	2242	2311	3.95e-9	SMART
VWC	2376	2439	1.04e-11	SMART
VWC	2479	2543	9.31e-5	SMART
CT	2625	2711	3.43e-32	SMART
low complexity region	2720	2733	N/A	INTRINSIC

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.8%
20x: 99.2%

Validation Efficiency

100% (56/56)

MGI Phenotype

PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased susceptibility to T. muris infection with persistent worm burden, goblet cell hyperplasia, and increased serum IFN-gamma despite a normal TH2-type immune response. A portion of mice show corneal opacity and poor tear quality. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 59 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aass	T	A	6: 23,075,200 (GRCm38)	D816V	possibly damaging	Het
Abca16	A	T	7: 120,514,705 (GRCm38)	N933I	probably benign	Het
Acly	A	T	11: 100,478,013 (GRCm38)		probably null	Het
Acox1	C	T	11: 116,183,580 (GRCm38)	G105D	possibly damaging	Het
Ankrd24	A	G	10: 81,646,794 (GRCm38)	E939G	possibly damaging	Het
Bard1	T	A	1: 71,066,942 (GRCm38)		probably null	Het
Brd4	G	T	17: 32,213,547 (GRCm38)	N579K	unknown	Het
C1qc	T	C	4: 136,890,281 (GRCm38)	Y168C	probably damaging	Het
Casp6	A	G	3: 129,912,209 (GRCm38)	D175G	probably damaging	Het
Ccdc83	A	T	7: 90,223,982 (GRCm38)	Y388*	probably null	Het
Clasrp	A	T	7: 19,584,591 (GRCm38)	*628R	probably null	Het
Cox4i1	A	G	8: 120,673,310 (GRCm38)	I111V	probably benign	Het
Cpvl	T	A	6: 53,926,901 (GRCm38)	D293V	probably damaging	Het
Epb41l4b	C	T	4: 57,076,913 (GRCm38)		probably null	Het
Frem2	C	A	3: 53,523,682 (GRCm38)	L2743F	possibly damaging	Het
Frmd4a	A	T	2: 4,601,349 (GRCm38)	H628L	probably benign	Het
Fyb	A	G	15: 6,660,703 (GRCm38)	D809G	probably damaging	Het
Gm19410	T	A	8: 35,807,498 (GRCm38)	M1491K	possibly damaging	Het
Gm3604	G	A	13: 62,369,996 (GRCm38)	H183Y	possibly damaging	Het
H1fnt	A	G	15: 98,256,684 (GRCm38)	S195P	unknown	Het
Lama2	T	C	10: 26,990,924 (GRCm38)	Y2858C	probably damaging	Het
Methig1	T	C	15: 100,353,531 (GRCm38)	F108L	probably benign	Het
Mfsd4b5	A	G	10: 39,970,255 (GRCm38)	V443A	probably damaging	Het
Myh9	C	T	15: 77,783,410 (GRCm38)	V608I	probably benign	Het
Myo1g	T	C	11: 6,514,849 (GRCm38)	D475G	probably damaging	Het
Neb	A	C	2: 52,280,716 (GRCm38)		probably null	Het
Nlrp1b	T	A	11: 71,168,839 (GRCm38)	I769F	probably benign	Het
Nol8	G	T	13: 49,662,266 (GRCm38)	V617F	possibly damaging	Het
Olfr715b	A	T	7: 107,106,533 (GRCm38)	C109*	probably null	Het
Pik3r2	A	G	8: 70,770,901 (GRCm38)	F346S	probably damaging	Het
Pou3f3	T	A	1: 42,698,148 (GRCm38)	F335I	probably damaging	Het
Ppp1r3e	T	C	14: 54,876,627 (GRCm38)	D196G	probably damaging	Het
Prpf40a	T	C	2: 53,151,745 (GRCm38)	T545A	probably damaging	Het
Rictor	C	T	15: 6,772,154 (GRCm38)	S441L	probably benign	Het
Rprd1a	T	A	18: 24,508,254 (GRCm38)	K102*	probably null	Het
Sim1	A	G	10: 50,896,035 (GRCm38)	T47A	possibly damaging	Het
Slc45a1	C	T	4: 150,644,041 (GRCm38)	A102T	probably damaging	Het
Slc6a11	C	T	6: 114,230,137 (GRCm38)	P361S	possibly damaging	Het
Slc9b2	T	C	3: 135,326,237 (GRCm38)	F286S	probably damaging	Het
Slco4a1	T	C	2: 180,471,237 (GRCm38)	S421P	probably benign	Het
Snap91	A	C	9: 86,798,709 (GRCm38)		probably null	Het
Sppl2a	A	G	2: 126,919,705 (GRCm38)	L293P	probably damaging	Het
Sval3	T	A	6: 41,972,426 (GRCm38)	I66K	possibly damaging	Het
Synj2bp	T	C	12: 81,504,537 (GRCm38)	I85V	probably benign	Het
Thop1	G	T	10: 81,080,191 (GRCm38)	A403S	probably benign	Het
Timd4	T	A	11: 46,815,527 (GRCm38)	M52K	probably damaging	Het
Tmco5b	A	G	2: 113,288,264 (GRCm38)	N111D	probably damaging	Het
Trip10	G	A	17: 57,261,667 (GRCm38)	V419I	possibly damaging	Het
Trpv3	T	C	11: 73,286,021 (GRCm38)	Y409H	probably damaging	Het
Tulp4	A	G	17: 6,233,124 (GRCm38)	T1143A	probably damaging	Het
Ugt2b5	A	T	5: 87,140,249 (GRCm38)	S20T	probably benign	Het
Unc5b	A	G	10: 60,775,044 (GRCm38)	F406L	probably benign	Het
Usf3	A	G	16: 44,220,521 (GRCm38)	E1788G	probably benign	Het
Usp45	A	G	4: 21,780,430 (GRCm38)	D27G	probably damaging	Het
Vmn2r100	G	A	17: 19,522,464 (GRCm38)	V367I	probably benign	Het
Vmn2r49	T	A	7: 9,976,258 (GRCm38)	K849I	probably damaging	Het
Zfp119b	A	T	17: 55,938,682 (GRCm38)	H501Q	probably damaging	Het
Zfp462	C	A	4: 55,016,958 (GRCm38)	H893N	probably benign	Het
Zkscan4	A	G	13: 21,479,355 (GRCm38)	E88G	probably damaging	Het

Other mutations in Muc5ac

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00899:Muc5ac	APN	7	141,812,703 (GRCm38)	missense	possibly damaging	0.93
IGL01064:Muc5ac	APN	7	141,807,473 (GRCm38)	missense	probably benign	0.12
IGL01155:Muc5ac	APN	7	141,806,943 (GRCm38)	splice site	probably benign
IGL01452:Muc5ac	APN	7	141,817,555 (GRCm38)	missense	probably benign	0.00
IGL01590:Muc5ac	APN	7	141,798,893 (GRCm38)	missense	probably benign	0.02
IGL02104:Muc5ac	APN	7	141,811,078 (GRCm38)	missense	probably damaging	0.98
IGL02152:Muc5ac	APN	7	141,800,177 (GRCm38)	missense	possibly damaging	0.86
IGL02153:Muc5ac	APN	7	141,818,800 (GRCm38)	nonsense	probably null
IGL02178:Muc5ac	APN	7	141,805,447 (GRCm38)	splice site	probably benign
IGL02403:Muc5ac	APN	7	141,803,450 (GRCm38)	missense	possibly damaging	0.71
IGL02576:Muc5ac	APN	7	141,817,044 (GRCm38)	missense	probably benign	0.01
IGL02665:Muc5ac	APN	7	141,791,086 (GRCm38)	missense	possibly damaging	0.71
IGL02704:Muc5ac	APN	7	141,795,263 (GRCm38)	missense	possibly damaging	0.71
IGL02808:Muc5ac	APN	7	141,805,775 (GRCm38)	missense	possibly damaging	0.72
IGL03283:Muc5ac	APN	7	141,813,781 (GRCm38)	missense	probably benign	0.34
IGL03384:Muc5ac	APN	7	141,812,403 (GRCm38)	missense	possibly damaging	0.71
IGL03046:Muc5ac	UTSW	7	141,795,213 (GRCm38)	missense	probably benign	0.27
PIT4515001:Muc5ac	UTSW	7	141,807,416 (GRCm38)	missense	probably damaging	0.99
R0092:Muc5ac	UTSW	7	141,818,630 (GRCm38)	missense	possibly damaging	0.72
R0145:Muc5ac	UTSW	7	141,795,275 (GRCm38)	missense	possibly damaging	0.71
R0147:Muc5ac	UTSW	7	141,811,039 (GRCm38)	missense	probably benign	0.08
R0363:Muc5ac	UTSW	7	141,800,960 (GRCm38)	missense	probably benign	0.01
R0384:Muc5ac	UTSW	7	141,812,251 (GRCm38)	missense	possibly damaging	0.71
R0440:Muc5ac	UTSW	7	141,792,034 (GRCm38)	nonsense	probably null
R0583:Muc5ac	UTSW	7	141,807,608 (GRCm38)	missense	probably damaging	0.99
R0616:Muc5ac	UTSW	7	141,796,244 (GRCm38)	missense	probably benign	0.02
R0682:Muc5ac	UTSW	7	141,805,669 (GRCm38)	missense	possibly damaging	0.53
R0685:Muc5ac	UTSW	7	141,807,709 (GRCm38)	missense	probably benign	0.03
R0883:Muc5ac	UTSW	7	141,796,265 (GRCm38)	missense	possibly damaging	0.71
R0924:Muc5ac	UTSW	7	141,807,515 (GRCm38)	missense	possibly damaging	0.68
R1300:Muc5ac	UTSW	7	141,816,929 (GRCm38)	missense	possibly damaging	0.73
R1315:Muc5ac	UTSW	7	141,807,323 (GRCm38)	missense	probably damaging	0.99
R1354:Muc5ac	UTSW	7	141,807,377 (GRCm38)	missense	probably damaging	0.99
R1484:Muc5ac	UTSW	7	141,813,892 (GRCm38)	splice site	probably null
R1599:Muc5ac	UTSW	7	141,798,903 (GRCm38)	missense	possibly damaging	0.52
R1758:Muc5ac	UTSW	7	141,801,531 (GRCm38)	missense	possibly damaging	0.86
R1837:Muc5ac	UTSW	7	141,807,086 (GRCm38)	missense	probably benign	0.00
R1911:Muc5ac	UTSW	7	141,796,304 (GRCm38)	missense	probably benign	0.18
R1922:Muc5ac	UTSW	7	141,793,689 (GRCm38)	missense	probably benign	0.03
R1966:Muc5ac	UTSW	7	141,803,376 (GRCm38)	missense	possibly damaging	0.92
R1994:Muc5ac	UTSW	7	141,813,152 (GRCm38)	missense	possibly damaging	0.93
R2056:Muc5ac	UTSW	7	141,792,035 (GRCm38)	missense	probably benign	0.01
R2126:Muc5ac	UTSW	7	141,810,742 (GRCm38)	missense	possibly damaging	0.84
R2170:Muc5ac	UTSW	7	141,812,347 (GRCm38)	missense	possibly damaging	0.93
R2258:Muc5ac	UTSW	7	141,791,008 (GRCm38)	missense	probably benign	0.41
R2259:Muc5ac	UTSW	7	141,791,008 (GRCm38)	missense	probably benign	0.41
R2293:Muc5ac	UTSW	7	141,807,199 (GRCm38)	missense	probably damaging	0.99
R2435:Muc5ac	UTSW	7	141,818,104 (GRCm38)	missense	possibly damaging	0.53
R2895:Muc5ac	UTSW	7	141,791,140 (GRCm38)	missense	possibly damaging	0.92
R2910:Muc5ac	UTSW	7	141,807,641 (GRCm38)	missense	probably damaging	0.99
R3154:Muc5ac	UTSW	7	141,792,736 (GRCm38)	splice site	probably null
R3762:Muc5ac	UTSW	7	141,807,475 (GRCm38)	missense	possibly damaging	0.53
R3791:Muc5ac	UTSW	7	141,798,501 (GRCm38)	missense	probably benign	0.32
R3806:Muc5ac	UTSW	7	141,813,734 (GRCm38)	missense	possibly damaging	0.91
R3825:Muc5ac	UTSW	7	141,814,723 (GRCm38)	missense	possibly damaging	0.92
R3888:Muc5ac	UTSW	7	141,791,224 (GRCm38)	missense	possibly damaging	0.51
R3929:Muc5ac	UTSW	7	141,802,892 (GRCm38)	missense	probably benign
R3981:Muc5ac	UTSW	7	141,813,775 (GRCm38)	missense	possibly damaging	0.86
R4034:Muc5ac	UTSW	7	141,799,844 (GRCm38)	critical splice donor site	probably null
R4043:Muc5ac	UTSW	7	141,807,478 (GRCm38)	missense	possibly damaging	0.53
R4061:Muc5ac	UTSW	7	141,811,130 (GRCm38)	missense	possibly damaging	0.85
R4106:Muc5ac	UTSW	7	141,802,835 (GRCm38)	missense	possibly damaging	0.86
R4206:Muc5ac	UTSW	7	141,817,110 (GRCm38)	missense	possibly damaging	0.73
R4613:Muc5ac	UTSW	7	141,791,103 (GRCm38)	missense	possibly damaging	0.93
R4719:Muc5ac	UTSW	7	141,789,763 (GRCm38)	missense	possibly damaging	0.83
R4751:Muc5ac	UTSW	7	141,817,601 (GRCm38)	missense	probably benign	0.00
R4789:Muc5ac	UTSW	7	141,798,882 (GRCm38)	missense	possibly damaging	0.86
R4928:Muc5ac	UTSW	7	141,817,902 (GRCm38)	nonsense	probably null
R4971:Muc5ac	UTSW	7	141,816,278 (GRCm38)	missense	possibly damaging	0.68
R4982:Muc5ac	UTSW	7	141,809,456 (GRCm38)	intron	probably benign
R5088:Muc5ac	UTSW	7	141,796,319 (GRCm38)	missense	possibly damaging	0.53
R5141:Muc5ac	UTSW	7	141,814,742 (GRCm38)	missense	possibly damaging	0.72
R5224:Muc5ac	UTSW	7	141,793,971 (GRCm38)	missense	probably benign	0.32
R5366:Muc5ac	UTSW	7	141,807,550 (GRCm38)	missense	probably benign	0.01
R5497:Muc5ac	UTSW	7	141,807,643 (GRCm38)	missense	probably damaging	0.99
R5507:Muc5ac	UTSW	7	141,807,832 (GRCm38)	missense	possibly damaging	0.72
R5643:Muc5ac	UTSW	7	141,793,715 (GRCm38)	critical splice donor site	probably null
R5811:Muc5ac	UTSW	7	141,798,984 (GRCm38)	missense	possibly damaging	0.51
R5946:Muc5ac	UTSW	7	141,817,907 (GRCm38)	missense	possibly damaging	0.73
R5970:Muc5ac	UTSW	7	141,790,669 (GRCm38)	nonsense	probably null
R5977:Muc5ac	UTSW	7	141,796,367 (GRCm38)	missense	possibly damaging	0.73
R6051:Muc5ac	UTSW	7	141,811,857 (GRCm38)	missense	possibly damaging	0.53
R6126:Muc5ac	UTSW	7	141,801,232 (GRCm38)	missense	possibly damaging	0.71
R6159:Muc5ac	UTSW	7	141,815,586 (GRCm38)	missense	possibly damaging	0.53
R6256:Muc5ac	UTSW	7	141,789,795 (GRCm38)	missense	possibly damaging	0.53
R6283:Muc5ac	UTSW	7	141,816,864 (GRCm38)	nonsense	probably null
R6341:Muc5ac	UTSW	7	141,801,492 (GRCm38)	missense	probably damaging	0.99
R6356:Muc5ac	UTSW	7	141,812,679 (GRCm38)	missense	probably benign	0.05
R6481:Muc5ac	UTSW	7	141,809,071 (GRCm38)	intron	probably benign
R6483:Muc5ac	UTSW	7	141,802,854 (GRCm38)	missense	probably benign	0.18
R6627:Muc5ac	UTSW	7	141,808,690 (GRCm38)	intron	probably benign
R6636:Muc5ac	UTSW	7	141,818,605 (GRCm38)	missense	possibly damaging	0.86
R6637:Muc5ac	UTSW	7	141,818,605 (GRCm38)	missense	possibly damaging	0.86
R6656:Muc5ac	UTSW	7	141,803,328 (GRCm38)	missense	probably damaging	0.98
R6721:Muc5ac	UTSW	7	141,798,992 (GRCm38)	missense	possibly damaging	0.71
R6794:Muc5ac	UTSW	7	141,809,552 (GRCm38)	intron	probably benign
R6844:Muc5ac	UTSW	7	141,809,744 (GRCm38)	intron	probably benign
R6847:Muc5ac	UTSW	7	141,809,744 (GRCm38)	intron	probably benign
R6852:Muc5ac	UTSW	7	141,816,907 (GRCm38)	missense	probably benign	0.03
R6862:Muc5ac	UTSW	7	141,809,744 (GRCm38)	intron	probably benign
R6863:Muc5ac	UTSW	7	141,809,744 (GRCm38)	intron	probably benign
R6864:Muc5ac	UTSW	7	141,809,744 (GRCm38)	intron	probably benign
R6865:Muc5ac	UTSW	7	141,809,744 (GRCm38)	intron	probably benign
R6874:Muc5ac	UTSW	7	141,809,744 (GRCm38)	intron	probably benign
R6875:Muc5ac	UTSW	7	141,809,744 (GRCm38)	intron	probably benign
R6876:Muc5ac	UTSW	7	141,809,744 (GRCm38)	intron	probably benign
R6877:Muc5ac	UTSW	7	141,809,744 (GRCm38)	intron	probably benign
R6889:Muc5ac	UTSW	7	141,809,744 (GRCm38)	intron	probably benign
R6920:Muc5ac	UTSW	7	141,793,298 (GRCm38)	missense	possibly damaging	0.86
R6998:Muc5ac	UTSW	7	141,818,714 (GRCm38)	missense	possibly damaging	0.92
R7017:Muc5ac	UTSW	7	141,809,687 (GRCm38)	intron	probably benign
R7091:Muc5ac	UTSW	7	141,809,687 (GRCm38)	intron	probably benign
R7092:Muc5ac	UTSW	7	141,809,687 (GRCm38)	intron	probably benign
R7092:Muc5ac	UTSW	7	141,809,648 (GRCm38)	intron	probably benign
R7110:Muc5ac	UTSW	7	141,799,822 (GRCm38)	missense	possibly damaging	0.95
R7117:Muc5ac	UTSW	7	141,813,822 (GRCm38)	nonsense	probably null
R7238:Muc5ac	UTSW	7	141,809,687 (GRCm38)	intron	probably benign
R7238:Muc5ac	UTSW	7	141,809,517 (GRCm38)	missense	unknown
R7396:Muc5ac	UTSW	7	141,808,415 (GRCm38)	missense	unknown
R7456:Muc5ac	UTSW	7	141,793,167 (GRCm38)	missense	probably benign	0.32
R7477:Muc5ac	UTSW	7	141,816,282 (GRCm38)	missense	possibly damaging	0.72
R7530:Muc5ac	UTSW	7	141,813,799 (GRCm38)	missense	possibly damaging	0.51
R7545:Muc5ac	UTSW	7	141,808,668 (GRCm38)	missense	unknown
R7604:Muc5ac	UTSW	7	141,809,709 (GRCm38)	missense	unknown
R7635:Muc5ac	UTSW	7	141,805,676 (GRCm38)	missense	probably damaging	0.98
R7635:Muc5ac	UTSW	7	141,805,753 (GRCm38)	missense	possibly damaging	0.53
R7650:Muc5ac	UTSW	7	141,809,422 (GRCm38)	missense	unknown
R7651:Muc5ac	UTSW	7	141,796,254 (GRCm38)	missense	possibly damaging	0.92
R7685:Muc5ac	UTSW	7	141,809,383 (GRCm38)	missense	unknown
R7720:Muc5ac	UTSW	7	141,809,303 (GRCm38)	missense	unknown
R7749:Muc5ac	UTSW	7	141,809,303 (GRCm38)	missense	unknown
R7751:Muc5ac	UTSW	7	141,809,303 (GRCm38)	missense	unknown
R7754:Muc5ac	UTSW	7	141,809,303 (GRCm38)	missense	unknown
R7798:Muc5ac	UTSW	7	141,794,041 (GRCm38)	critical splice donor site	probably null
R7835:Muc5ac	UTSW	7	141,809,303 (GRCm38)	missense	unknown
R7837:Muc5ac	UTSW	7	141,815,963 (GRCm38)	missense	possibly damaging	0.53
R7858:Muc5ac	UTSW	7	141,803,429 (GRCm38)	missense	possibly damaging	0.51
R7866:Muc5ac	UTSW	7	141,795,852 (GRCm38)	missense	probably benign	0.00
R7874:Muc5ac	UTSW	7	141,809,303 (GRCm38)	missense	unknown
R7876:Muc5ac	UTSW	7	141,809,303 (GRCm38)	missense	unknown
R7877:Muc5ac	UTSW	7	141,809,303 (GRCm38)	missense	unknown
R7881:Muc5ac	UTSW	7	141,809,303 (GRCm38)	missense	unknown
R7884:Muc5ac	UTSW	7	141,809,303 (GRCm38)	missense	unknown
R7921:Muc5ac	UTSW	7	141,809,687 (GRCm38)	intron	probably benign
R7976:Muc5ac	UTSW	7	141,809,791 (GRCm38)	missense	unknown
R8104:Muc5ac	UTSW	7	141,804,783 (GRCm38)	missense	possibly damaging	0.96
R8177:Muc5ac	UTSW	7	141,807,331 (GRCm38)	missense	probably damaging	1.00
R8214:Muc5ac	UTSW	7	141,802,948 (GRCm38)	missense	possibly damaging	0.53
R8292:Muc5ac	UTSW	7	141,809,263 (GRCm38)	missense	unknown
R8386:Muc5ac	UTSW	7	141,807,634 (GRCm38)	missense	possibly damaging	0.93
R8400:Muc5ac	UTSW	7	141,810,476 (GRCm38)	missense	probably damaging	0.99
R8504:Muc5ac	UTSW	7	141,807,155 (GRCm38)	missense	probably damaging	1.00
R8709:Muc5ac	UTSW	7	141,816,926 (GRCm38)	missense	possibly damaging	0.96
R8725:Muc5ac	UTSW	7	141,809,744 (GRCm38)	intron	probably benign
R8727:Muc5ac	UTSW	7	141,809,744 (GRCm38)	intron	probably benign
R8754:Muc5ac	UTSW	7	141,800,271 (GRCm38)	missense	possibly damaging	0.85
R8769:Muc5ac	UTSW	7	141,818,872 (GRCm38)	missense	probably damaging	1.00
R8933:Muc5ac	UTSW	7	141,789,756 (GRCm38)	missense	possibly damaging	0.59
R8939:Muc5ac	UTSW	7	141,793,354 (GRCm38)	missense	probably damaging	0.98
R9049:Muc5ac	UTSW	7	141,808,975 (GRCm38)	missense	unknown
R9124:Muc5ac	UTSW	7	141,809,792 (GRCm38)	missense	unknown
R9131:Muc5ac	UTSW	7	141,809,792 (GRCm38)	missense	unknown
R9132:Muc5ac	UTSW	7	141,809,792 (GRCm38)	missense	unknown
R9135:Muc5ac	UTSW	7	141,798,481 (GRCm38)	missense	probably damaging	0.99
R9156:Muc5ac	UTSW	7	141,809,792 (GRCm38)	missense	unknown
R9157:Muc5ac	UTSW	7	141,809,792 (GRCm38)	missense	unknown
R9159:Muc5ac	UTSW	7	141,809,792 (GRCm38)	missense	unknown
R9160:Muc5ac	UTSW	7	141,809,792 (GRCm38)	missense	unknown
R9161:Muc5ac	UTSW	7	141,799,289 (GRCm38)	missense	possibly damaging	0.53
R9175:Muc5ac	UTSW	7	141,812,356 (GRCm38)	missense	possibly damaging	0.92
R9183:Muc5ac	UTSW	7	141,798,900 (GRCm38)	missense	possibly damaging	0.71
R9218:Muc5ac	UTSW	7	141,807,361 (GRCm38)	missense	probably damaging	0.99
R9219:Muc5ac	UTSW	7	141,817,063 (GRCm38)	nonsense	probably null
R9239:Muc5ac	UTSW	7	141,800,217 (GRCm38)	missense	probably damaging	0.99
R9246:Muc5ac	UTSW	7	141,810,478 (GRCm38)	missense	probably benign	0.11
R9287:Muc5ac	UTSW	7	141,807,889 (GRCm38)	missense	probably damaging	0.99
R9320:Muc5ac	UTSW	7	141,815,518 (GRCm38)	missense	probably benign	0.01
R9327:Muc5ac	UTSW	7	141,811,692 (GRCm38)	missense	possibly damaging	0.86
R9428:Muc5ac	UTSW	7	141,808,822 (GRCm38)	missense	unknown
R9430:Muc5ac	UTSW	7	141,808,832 (GRCm38)	missense	unknown
R9454:Muc5ac	UTSW	7	141,808,694 (GRCm38)	missense	unknown
R9483:Muc5ac	UTSW	7	141,811,728 (GRCm38)	nonsense	probably null
R9581:Muc5ac	UTSW	7	141,810,062 (GRCm38)	missense	unknown
R9610:Muc5ac	UTSW	7	141,796,341 (GRCm38)	missense	possibly damaging	0.86
R9642:Muc5ac	UTSW	7	141,795,864 (GRCm38)	missense	possibly damaging	0.71
R9684:Muc5ac	UTSW	7	141,811,061 (GRCm38)	missense	probably benign	0.41
R9760:Muc5ac	UTSW	7	141,807,248 (GRCm38)	missense	probably benign	0.05
R9778:Muc5ac	UTSW	7	141,795,284 (GRCm38)	nonsense	probably null
X0060:Muc5ac	UTSW	7	141,803,333 (GRCm38)	missense	possibly damaging	0.71
Z1088:Muc5ac	UTSW	7	141,811,692 (GRCm38)	missense	possibly damaging	0.86
Z1088:Muc5ac	UTSW	7	141,809,744 (GRCm38)	intron	probably benign
Z1177:Muc5ac	UTSW	7	141,818,040 (GRCm38)	missense	probably benign	0.33
Z1177:Muc5ac	UTSW	7	141,809,224 (GRCm38)	missense	unknown

Predicted Primers

PCR Primer
(F):5'- TCACCCAATACAGGAAAGGC -3'
(R):5'- GGTGCTGGCCTTTCCTGTA -3'

Sequencing Primer
(F):5'- TACAGGAAAGGCCAGCACC -3'
(R):5'- CCTTTCCTGTATTGGGTGAGC -3'

Posted On

2019-11-26